MOCHIDA Joji 持田讓治

… Alternative Names

持田譲治モチダジョウジ

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Researcher Number	30129697
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2014: Tokai University, 医学部, 教授
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 安全性 / 凍結保存法 / 活性化髄核細胞 / 椎間板変性 / 変性抑制 / 椎間板移植 / 凍結保存 / 骨髄間葉系幹細胞 / 髄核細胞 Except Principal Investigator 線維輪細胞 … More / 再生医学 / 線維輪 / 幹細胞 / 再生医療 / 椎間板 Less

Analysis of appropriate cell source for efficient annulus fibrosis regeneration
- Principal Investigator
  
  SAKAI Daisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University
Disc repair with transplantation of activated nucleus pulposus cells-how to preserve the cells and its safety-Principal Investigator
- Principal Investigator
  
  MOCHIDA Joji, 持田譲治
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University

All 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study2015
- Author(s)
  Sakai D, Nishimura K, Tanaka M, Nakajima D, Grad S, Alini M, Kawada H, Ando K, Mochida J
- Journal Title
  
  Spine Journal
  
  Volume: 15 Issue: 6 Pages: 1356-1365
- DOI
  10.1016/j.spinee.2013.07.491
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] CCL5/RANTES is a key chemoattractant released by degenerative intervertebral discs in organ culture2014
- Author(s)
  Pattappa G, Peroglio M, Sakai D, Mochida J, Benneker LM, Alini M, Grad S
- Journal Title
  
  European Cells and Materials
  
  Volume: 27 Pages: 124-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] 運動器再生医療研究の最先端椎間板再生の今2014
- Author(s)
  酒井大輔、持田讓治
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 88 Pages: 216-223
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] 【脊椎脊髄の科学-基礎と臨床の進歩Review 2014】 (第1章)基礎科学　椎間板再生の現況と問題点2014
- Author(s)
  酒井大輔、持田讓治
- Journal Title
  
  脊椎脊髄ジャーナル
  
  Volume: 27 Pages: 239-246
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] Cell Signaling Pathways Related to Pain Receptors in the Degenerated Disk2013
- Author(s)
  Hiyama A, Sakai D, Mochida J
- Journal Title
  
  Global Spine Journal
  
  Volume: 3 Pages: 165-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] C-Fos Regulation by the MAPK and PKC Pathways in Intervertebral Disc Cells2013
- Author(s)
  Yokoyama K1, Hiyama A, Arai F, Nukaga T, Sakai D, Mochida J
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 9 Pages: e73210-e73210
- DOI
  10.1371/journal.pone.0073210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] A Cre Knock-in Mouse Line on the Sickle Tail Locus Induces Recombination in the Notochord and Intervertebral Discs.2012
- Author(s)
  Abe, K. et al.
- Journal Title
  
  Genesis
  
  Volume: 50 Issue: 10 Pages: 758-765
- DOI
  10.1002/dvg.22035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-22500392, KAKENHI-PROJECT-22791388, KAKENHI-PROJECT-23300159, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-24592213, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-24115712
[Journal Article] The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells.2012
- Author(s)
  Hiyama A, Arai F, Sakai D, Yokoyama K, Mochida J.
- Journal Title
  
  Arthritis Research and Therapy
  
  Volume: 14 Issue: 3
- DOI
  10.1186/ar3830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592213
[Journal Article] Homing of mesenchymal stem cells in induced degenerative intervertebral discs in a whole organ culture system2012
- Author(s)
  Illien-Junger S, Sakai D, et al
- Journal Title
  
  Spine
  
  Volume: 37(In press) Issue: 22 Pages: 1865-1873
- DOI
  10.1097/brs.0b013e3182544a8a
- NAID
  10031169857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791406, KAKENHI-PROJECT-24592213
[Journal Article] The expression and role of non-canonical(PKC) signaling in nucleus pulposus cell metabolism2012
- Author(s)
  Arai F, Hiyama A, Sakai D, Yokoyama K, Mochida J
- Journal Title
  
  J Orthop Res
  
  Volume: 30(In press) Issue: 9 Pages: 1478-85
- DOI
  10.1002/jor.22095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791406, KAKENHI-PROJECT-24592213
[Journal Article] Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc.2012
- Author(s)
  Sakai, D. et al.
- Journal Title
  
  Nature Comm.
  
  Volume: 3 Issue: 1 Pages: 1264-1264
- DOI
  10.1038/ncomms2226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390248, KAKENHI-PROJECT-24592212, KAKENHI-PROJECT-24592213
[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells2010
- Author(s)
  Watanabe T, Sakai D, Yamamoto Y, Iwashina T, Serigano K, Tamura F, Mochida J
- Journal Title
  
  Journal of Orthopaedic Research
  
  Volume: Vol.28 Pages: 623-630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells.2010
- Author(s)
  Watanabe T, Sakai D, Yamamoto Y, Iwashina T, Serigano K, Tamura F, Mochida J.
- Journal Title
  
  Journal of Orthopaedic Research Vol 28
  
  Pages: 623-630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells2009
- Author(s)
  Watanabe T, Sakai D, YamamotoY, Iwashina T, Serigano K, Tamura F, Mochida J
- Journal Title
  
  J Orthop Res. 28
  
  Pages: 623-630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Journal Article] 細胞レベルからの椎間板再生 -細胞移植療法のその先に-2009
- Author(s)
  酒井大輔、持田譲治
- Journal Title
  
  日本腰痛学会雑誌第15巻
  
  Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Journal Article] Differential phenotype of intervertebral disc cells : microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus2009
- Author(s)
  Sakai D, Nakai T, Mochida J, Alini M, Grad S
- Journal Title
  
  Spine 34
  
  Pages: 1448-1456
- NAID
  10027244193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Journal Article] stem cell applications in intervertebral discrepair2008
- Author(s)
  檜山明彦, 持田譲治, 酒井大輔
- Journal Title
  
  Cell and Molecular Biology 54
  
  Pages: 24-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] Non-notochordal origin in chondrocyte-like cells of the nucleus pulposus appearing in early stage disc degeneration in the mouse model2012
- Author(s)
  田中真弘、酒井大輔、檜山明彦、田村太、新井文征、中島大輔、中井知子、持田讓治
- Organizer
  2012 Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  San Francisco CA, USA
- Year and Date
  2012-02-05
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 活性化髄核細胞の凍結保存方法についての基礎的検討22011
- Author(s)
  田中真弘、酒井大輔、檜山明彦、田村太、新井文征、中島大輔、中井知子、持田讓治
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  ベイシア文化ホール、前橋
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] Basic research on cryopreservation of activated human nucleus pulposus cells2011
- Author(s)
  田中真弘、酒井大輔、檜山明彦、田村太、新井文征、中島大輔、中井知子、持田讓治
- Organizer
  2011 Annual Meeting of International Society for the Study of the Lumbar Spine
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 活性化髄核細胞の凍結保存方法についての基礎的検討(第2報)2011
- Author(s)
  田中真弘, 酒井大輔, 檜山明彦, 新井文征, 中島大輔, 中井知子, 持田讓治
- Organizer
  日本整形外科学会雑誌
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] Basic research on cryopreservation of aqctivated human nucleus pulposus cells2011
- Author(s)
  Tanaka M, Sakai D, Mochida J
- Organizer
  ISSLS meeting at Gotenburg
- Place of Presentation
  Sweden
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板再生のための細胞移植療法臨床研究の進捗および幹細胞研究による新展開2010
- Author(s)
  酒井大輔、田中真弘、新井文征、持田讓治
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板再生のための細胞移植療法臨床研究の進捗および幹細胞研究による新展開2010
- Author(s)
  酒井大輔、田中真弘、新井文征、持田讓治
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 活性化髄核細胞の凍結保存法についての基礎的検討2010
- Author(s)
  田中真弘、酒井大輔、新井文征、持田讓治
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板再生のための細胞移植療法臨床研究の進捗および幹細胞研究による新展開2010
- Author(s)
  酒井大輔、田中真弘、新井文征、持田讓治
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 活性化髄核細胞の凍結保存法についての基礎的検討2010
- Author(s)
  田中真弘、酒井大輔、新井文征、持田讓治
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] シンポジウム自家骨髄間葉系幹細胞により活性化された椎間板髄核細胞を用いた椎間板再生実現過程での問題点と対処2009
- Author(s)
  持田譲治, 酒井大輔
- Organizer
  第8回日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板ヘルニアに対する最新医療-橋渡し研究の経過-2009
- Author(s)
  持田譲治
- Organizer
  第112回中部日本整形外科災害外科学会・学術集会
- Place of Presentation
  京都
- Year and Date
  2009-04-09
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板再生のための細胞移植療法2009
- Author(s)
  持田譲治
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] シンウポジム骨髄間葉系幹細胞により活性化された髄細胞を用いた椎間板再生医療2009
- Author(s)
  持田譲治
- Organizer
  第31回日本バイオマテリアル学会大会
- Place of Presentation
  京都
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 細胞移植による椎間板再生医療2008
- Author(s)
  持田譲治
- Organizer
  日本腰痛学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 椎間板再生臨床応用への橋渡し研究の現況2008
- Author(s)
  持田譲治
- Organizer
  第37回日本脊椎脊髄病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] Trends of spinal basic research in Japan Activation of nucleus pulposus cells by bone marrow-derived Mesenchymal stem cell2008
- Author(s)
  持田譲治
- Organizer
  The 7th combined comgress of the spine and pediatric sections of Asia Pacific Orthopaedic Associatio
- Place of Presentation
  済州島、韓国
- Data Source
  KAKENHI-PROJECT-20390405
[Presentation] 再生医療の最先端椎間板再生　ES細胞による細胞移植の可能性と線維輪再生に向けた新展開
- Author(s)
  酒井大輔, 中井知子, 額賀唯至, 持田讓治
- Organizer
  第87回日本整形外科学会学術総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2014-05-23 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24592213

1. SAKAI Daisuke (10408007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
2. IWASHINA Tooru (10433913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. HIYAMA Akihiko (00514382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. NAKAI Tomoko (20624589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 持田譲治 (50174347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MOCHIDA Joji 持田 讓治

持田 譲治 モチダ ジョウジ

Research Projects

Research Products

Co-Researchers

Analysis of appropriate cell source for efficient annulus fibrosis regeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Disc repair with transplantation of activated nucleus pulposus cells-how to preserve the cells and its safety-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCL5/RANTES is a key chemoattractant released by degenerative intervertebral discs in organ culture2014

Author(s)

Journal Title

Data Source

[Journal Article] 運動器再生医療研究の最先端 椎間板再生の今2014

Author(s)

Journal Title

Data Source

[Journal Article] 【脊椎脊髄の科学-基礎と臨床の進歩Review 2014】 (第1章)基礎科学 椎間板再生の現況と問題点2014

Author(s)

Journal Title

Data Source

[Journal Article] Cell Signaling Pathways Related to Pain Receptors in the Degenerated Disk2013

Author(s)

Journal Title

Data Source

[Journal Article] C-Fos Regulation by the MAPK and PKC Pathways in Intervertebral Disc Cells2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Cre Knock-in Mouse Line on the Sickle Tail Locus Induces Recombination in the Notochord and Intervertebral Discs.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Homing of mesenchymal stem cells in induced degenerative intervertebral discs in a whole organ culture system2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The expression and role of non-canonical(PKC) signaling in nucleus pulposus cell metabolism2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells2010

Author(s)

Journal Title

Data Source

[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell-to-cell contact with autologous mesenchymal stem cells2009

Author(s)

Journal Title

MOCHIDA Joji 持田讓治

持田譲治モチダジョウジ

[Journal Article] 運動器再生医療研究の最先端椎間板再生の今2014

[Journal Article] 【脊椎脊髄の科学-基礎と臨床の進歩Review 2014】 (第1章)基礎科学　椎間板再生の現況と問題点2014

[Presentation] 椎間板再生のための細胞移植療法臨床研究の進捗および幹細胞研究による新展開2010

[Presentation] 椎間板再生のための細胞移植療法臨床研究の進捗および幹細胞研究による新展開2010