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Ozawa Keiya  小澤 敬也

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… Alternative Names

OZAWA Keiya  小澤 敬也

小沢 敬也  オザワ ケイヤ

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Researcher Number 30137707
Other IDs
External Links
Affiliation (Current) 2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2014: 自治医科大学, 医学部, 客員教授
1994 – 2013: 自治医科大学, 医学部, 教授
2006: 自治医科大学, 医学部内科学講座, 教授
2006: Jichi Medical University, Department of Medicine, Professor, 医学部内科講座, 教授
2003 – 2004: 自治医科大学, 遺伝子治療部, 教授 … More
2002: 自治大学, 遺伝子治療部, 教授
1998 – 2000: 自治医科大学, 教授
1994: 東京大学, 医学科学研究所, 助教授
1990 – 1993: Imsut, Associate Professor., 医科学研究所, 助教授
1990: 東京大学医科学研究所, 助教授
1988 – 1989: 東京大学, 医科学研究所, 講師 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology / Biological Sciences
Except Principal Investigator
Hematology / Biological Sciences / Pediatrics / Obstetrics and gynecology / Cerebral neurosurgery / Obstetrics and gynecology / Pediatrics … More / Circulatory organs internal medicine / Orthopaedic surgery / Virology / General medical chemistry Less
Keywords
Principal Investigator
遺伝子治療 / 遺伝子導入 / ITR / Rep / AAVベクター / 造血幹細胞 / Gene transfer / AAVS1領域 / 遺伝子組込み / 選択的増幅遺伝子 … More / TVI法 / AAV / エストロゲン受容体 / 組織特異性 / AAV vector / TVI method / Gene therapy / パッケージング細胞株 / G-CSF受容体 / 自殺遺伝子 / レトロウイルスベクター / Msx1 / ex vivo expansion / in vivo expansion / Selective amplifier gene / Hematopoietic stem cell / 体外増幅 / 体内増幅 / CD34 / C3H10T1 / 幹細胞 / 間葉系幹細胞 / 癌 / バキュロウイルス / がん遺伝子治療 / サイトカイン / アポトーシス / GーCSF / Stem cell / Hematopoietic system / Skeletal muscle / Plasticity / Transdifferentiation / Dedifferentiation / AVVベクター / 造血系 / 骨格筋 / 可塑性 / 分化転換 / 脱分化 / adaptor molecule / adenoviral vector / targeted vector integration / protein-supplement gene therapy / tissue specificity / 血清型 / 免疫反応 / 凝固因子 / エリスロポエチン / アダプター分子 / アデノウイルスベクター / 染色体部位特異的遺伝子組込み / 蛋白質補充遺伝子療法 / AAVS1 locus / packaging cell line / differentiation-regulatory gene / 分化制御遺伝子 / AAVSI locus / Integration / Gene theray / Estrogen receptor / G-CSF receptor / 対外増幅 / AVVS1 locus / integration / AAVS1 / Hematopoiesis-supporting ability / Differentiation induction / 2 cell / Preadipocyte / Stromal cell / 造血支持能 / 分化誘導 / 2細胞 / 前脂肪細胞 / ストローマ細胞 / 血液腫瘍学 / 造血器腫瘍 / Tリンパ球 / キメラ抗原受容体 / 細胞療法 / 免疫療法 / iPS細胞 / 再生医療 / ゲノム / 移植再生医療 / 可溶型TRAIL / 細胞治療 / 抗腫瘍性サイトカイン / 腫瘍集積性 / 悪性リンパ腫 / 担癌ヌードマウス / ヒストン脱アセチル化酵素阻害剤 / リンパ行性転移抑制 / 抗腫瘍血管遺伝子療法 / VEGF-C / sFlt-4 / sFlt-1 / リンパ管新生 / 血管新生 / バイオテクノロジー / ウイルス / 遺伝子 / NK4 / IL-10 / 可溶型Flt-1 / 卵巣癌 / クローン優位性 / ケモカイン / ジーンターゲティング / 発作性夜間血色素尿症(PNH) / V-J組換え / コンディショナルターゲティング / トランスポゾンシステム / サイトカインレセプター / 突然変異マウス / コモンマーモセット / ヘルパープラスミド / 分化シグナル / 増殖シグナル / 細胞制御 / G-CSF / Fas / ストロース細胞 / RTーPCR法 / エピト-プ・マッピング / 抗GーCSF抗体 / GーCSFレセプタ- / レセプタ-結合ドメイン / 顆粒球コロニ-刺激因子 / 細胞接着 / 遺伝子発現調節 / ILー6 / ストロ-マ細胞 / 細胞障害作用 / JK-1細胞 / ウイルス非構造蛋白 / 造血障害 / B19パルボウイルス … More
Except Principal Investigator
遺伝子治療 / レトロウイルスベクター / 造血幹細胞 / gene therapy / IL-10 / chronic granulomatous disease / 慢性肉芽腫症 / アデノ随伴ウイルス / アデノウイルスベクター / 遺伝子導入 / hematopoietic stem cells / 選択的増幅遺伝子 / ovarian cancer / 腹膜播種 / bikunin / PTEN / NK4 / 卵巣癌 / green fluorescent protein / 血管新生 / 細胞移植 / ストロ-マ細胞 / 骨髄移植 / 白血病 / translational research / 移植・再生医療 / トランスレーショナルリサーチ / peritoneal dissemination / soluble Flt-1 / TGF-β / LacZ / TS / UTI / ES細胞 / アルカリフォスファターゼ / Evi-1 / GIG-1 / Hematopoietic Stem Cell / 幹細胞 / アデノウイルス / ウイルスベクター / サイトカイン / Fyn / SH3 / v-Crk / Src / 骨髄性白血病 / loxP / Cre / パーキンソン病 / 神経細胞死 / 細胞ターゲッティング / 双特異性抗体 / 単クローン抗体 / 抗腫瘍免疫 / がん / SCF / 造血因子 / CD34 / GーCSF / 02Receptor for granulocyte colony-stimulating factor, / Intracellular signal transduction / Acute Myelogenous leukemia, / Granulocyte colony-stimulating factor, / 受容体 / 成熟停止 / コロニー刺激因子 / 顆粒球 / アルカリフォスファタ-ゼ / ミエロペルオキシタ-ゼ / 細胞内情報伝達 / 細胞内シグナル伝達系 / 顆粒球コロニ-刺激因子受容体 / 顆粒球コロニ-刺激因子 / basic Research / adeno-associated virus / molecular targeted thera / 基礎研究 / 分子標的治療 / gene expression profiling / DNA microarray / acute mveloid leukemia / 網羅的遺伝子発現解析 / 網羅的清伝子発現解析 / DNAチップ / マイクロRNA / 急性骨髄性白血病 / リシークエンス / CD133 / DNAマイクロアレイ / biotechnology / neuronal diseases / virus / gene / 動脈硬化症 / 脳血管障害 / 脳腫瘍 / アデノ随判ウイルス / バイオテクノロジー / 脳神経疾患 / ウイルス / 遺伝子 / cell and tissue / transplantation / エリスロポエチン受容体 / 浩血幹細胞 / 選択的増幅潰伝子 / 浩血微小環境 / 慢性肉弾腫症 / 顆粒球コロニー増殖因子受容体 / エリスロポチエン受容体 / 骨髄腔内注入法 / 造血微小環境 / 細胞・組織 / phagocytes / innate immunity / retroviral vector / selecvtive amplifier gene / 活性酸素 / 食細胞 / 自然免疫 / Pre-clinical studies / Gene therapy / Cardiac failure / rAAVベクター / サルゴグリカン / 拡張型心筋症 / ジストロフィン / 細胞膜の透過性 / 前臨床試験 / 心不全 / molecular biology / angiogenesis / TPI / TP / AAV / 血管新生抑制 / 可溶型Flt-1 / インターロイキン-10 / ビクニン / 分子生物学 / AAV vector / cartilage repair / periosteal cell / アデノ随伴ウイルスベクター / TGF-B / アデノ髄伴ウイルスベクター / 軟骨修復 / 骨膜細胞 / in utero transplantation / cynomolgus monkeys / embryonic stem cells / 霊長類モデル / 造血斡細胞 / ヒツジ / テラトーマ / カニクイザル / SIVベクター / 胎仔移植 / selective amplifier gene / thymidylate synthase / AAVベクター / 緑色蛍光蛋白質 / Clover yellow vein virus / protease / Rep protein / nuclear proteins / packaging cells / adeno-associated virus vector / クローバーイエローベインウイルス / プロテアーゼ / Rep蛋白質 / 核蛋白質 / パッケージング細胞 / Home page / Abstract / Gene transfer / Transcriptional regulation / Signal transductiom / Cell differentiation / Stemness / 遺伝子操作 / 転写調節 / シグナル伝達 / 分化決定 / 多能性造血幹細胞 / 幹細胞システム / Evi-1転写制御因子 / 負のシグナル伝達機構 / STAT3 / gp130 / 造血システム / HIVベクター / クロストーク / 転写 / シグナル / 多分化能 / 間葉系幹細胞 / 相互変換 / 細胞接着 / 再生医学研究 / 自己複製 / ホームページ作成 / 冊子作成 / 転写制御 / シグナル制御 / 分化制御 / 未分化性維持機構 / hematopoietic stem cell / retrovirus vector / green flnogescent protein / PEBP2 beta / PEBP2 alpha / NK cell / neutrophil / maturation arrest / transcriptional factor / 転写活性因子 / ABL遺伝子 / BCR / 好中球系細胞 / GIG-1蛋白 / 骨髄細胞分化マーカー / IFN-α抵抗性 / TF-1細胞 / 慢性骨髄性白血病細胞 / ETS遺伝子 / GATA遺伝子 / Evi-1遺伝子 / GIG-1タンパク / PEBP2β / PEBP2α / NK細胞 / 好中球 / 分化停止機構 / 転写制御因子 / cDNA Cloning / SCID mouse / Mast cell / Cytokine / Hematopoietic Factor / MB-1 / Undifferentiated Leukemia Cell Line / 細胞相互作用 / 造血前駆細胞 / 骨髄芽球 / ヌ-ドマウス / 慢性骨髄性白血病 / ストローマ細胞 / 白血病細胞株 / ヌードマウス / 精製 / cDNAライブラリー / cDNAクローニング / SCIDマウス / 肥満細胞 / HB-1 / 未分化白血病細胞株 / 染色体遺伝子組込み / c-Kit / CAR / AAVS1 / Rep / 染色体部位特異的遺伝子組込み / リボザイム / アデノウィルス / 遺伝子置換 / ウィルスベクター / 発現制御 / 遺伝子置換反応 / FRT / FLP / 部位特異的組換え酵素 / guttedベクター / 癌遺伝子 / レトロウィルス / ベクター開発 / 神経栄耀因子 / 環境因子 / 黒質神経毒 / 遺伝的素因 / 家族性パーキンソン病 / SHZ / チロシンキナーゼ / p-130^<cas> / SH2 / インテグリン / Fak / P130^<cas> / タ-グティング療法 / トキシン / G-CSF / 細胞標的化 / GM-CSF遺伝子導入腎癌細胞 / 免疫遺伝子治療法 / 細胞障害性Tリンパ球(CTL)活性 / リンパ球輸注療法 / パーキンソン病診断 / ドーパミントランスポーター / 抗パーキンソン病薬 / 発症物質 / β-カルボリニウム イオン / TIQ / パーキンソン病発症物質 / CALLA抗体 / 白血病細胞 / 遺伝子診断 / 温度勾配電気泳動 / PCR / TCR(T細胞抗原受容体) / リポソーム法 / トランス再構成 / 染色体異常 / 免疫不全 / 抗原受容体遺伝子 / ACK-2 / 骨髄幹細胞 / bispecific抗体 / トランスジェニックマウス / 顆粒球コロニ-刺激因子(GーCSF) / ガンシクロビル / ヘルペスウルスキミジンキナ-ゼ遺伝子 / 未梢血幹細胞移植 / 自家骨髄移植 / Ku812 / JK1 / 赤芽球細胞 / p53 / ヘルパ-細胞 / レトロウィルスベクタ- / ヒトL型ピルビン酸キナ-ゼ / 末梢血単核細胞移植 / ILー6 / cーkit / 遺伝子発現コントロ-ル / hG-CSF高発現細胞株 / 拡散チャンバ- / BMGNeoプラスミド / ヒト顆粒球コロニ-刺激因子(hG-CSF) Less
  • Research Projects

    (66 results)
  • Research Products

    (169 results)
  • Co-Researchers

    (93 People)
  •  Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptorPrincipal Investigator

    • Principal Investigator
      OZAWA keiya
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of a site-specific gene insertion technology for regenerative medicine:Basic study using developmental engineeringPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of gene therapy using bone-marrow-derived mesenchymal stem cellsPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of gene therapy for malignant lymphoma using mesenchymal stem cells with tumor-accumulating capacityPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of AAV (adeno-associated virus) vectors and their application to cancer therapyPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Jichi Medical University
  •  Molecular targeted therapy of hematological malignancies based on the genomic information

    • Principal Investigator
      MANO Hiroyuki
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Jichi Medical University
  •  Molecular targeted and gene therapy using adeno-associated virus vector to suppress the peritoneal dissemination in ovarian cancer

    • Principal Investigator
      OHWADA Michitaka
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Jichi Medical University
  •  DEDIFFERENTIATION OF NON-HEMATOPOIETIC TISSUE BY GENETIC MANIPULATION AND ITS ACQUISITION OF PLASTICITY AND HEMATOPOIETIC TRANSDIFFERENTIATIONPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      JICHI MEDICAL UNIVERSITY
  •  Gene therapy for chronic granulomatous disease in combination with selective cell amplification and utilizing hematopoietic microenvironment

    • Principal Investigator
      KUME Akihiro
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      JICHI MEDICAL UNIVERSITY
  •  Gene therapy for neuronal diseases using rAAV

    • Principal Investigator
      OKADA Takashi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      National Institute of Neuroscience, National Center of Neurology and Psychiatry
      Jichi Medical University
  •  アデノ随伴ウイルス(AAV)ベクターの開発とその癌遺伝子治療への応用Principal Investigator

    • Principal Investigator
      小澤 敬也 (小沢 敬也)
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Jichi Medical University
  •  神経幹細胞への染色体部位特異的遺伝子組込み法の開発

    • Principal Investigator
      OKADA Takashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Jichi Medical University
  •  Preclinical tests for gene therapy of advanced heart failure

    • Principal Investigator
      TOYO-OKA Teruhiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Development of basic technologies for gene therapy using adeno-associated virus (AAV)Principal Investigator

    • Principal Investigator
      OZAWA Kaiya
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Gene therapy for chronic granulomatous disease combined with in vivo expansion of transduced hematopoietic cells.

    • Principal Investigator
      KUME Akihiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Jichi Medical School
  •  A basic study on gene therapy for ovarian cancer to inhibition peritoneal dissemination

    • Principal Investigator
      SUZUKI Mitsuaki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Jichi Medical University
  •  がん治療をめざしたアデノウイルスベクターを用いた発現制御法の開発

    • Principal Investigator
      斎藤 泉
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  AAVベクターによる抗腫瘍血管療法と新規アデノ-AAVハイブリッドベクターの開発

    • Principal Investigator
      久米 晃啓
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Jichi Medical University
  •  Development of the gene therapy technologies using adeno-associated virus (AAV)Principal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  In utero transplantation of stem cells in cynomolgus monkeys

    • Principal Investigator
      HANAZONO Yutaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Gene transfer to periosteum-derived cells for cartilage repair

    • Principal Investigator
      KAWAI Kosei, 河合 孝誠
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Department of Orthpaedic Surgery, Yokohama city university
  •  がん遺伝子治療ベクターの基礎研究

    • Principal Investigator
      斎藤 泉
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  新しい発現クローニング法を用いた慢性骨髄性白血病急性転化責任遺伝子の単離

    • Principal Investigator
      宮里 彰
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development and application of the technologies for manipulationg hematopoietic stem cells using cell-regulatory genesPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Gene therapy of chronic granulomatous disease with GFP-tagged retrovirus vectors

    • Principal Investigator
      KUME Akihiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Jichi Medical University
  •  A basic study of gene therapy for ovarian cancer : inhibition of angiogenesis and metastasis/invasion

    • Principal Investigator
      OHWADA Michitaka
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Jichi Medical School
  •  Gene transfer into hematopoietic stem cells and gene therapy for chronic granulomatous disease

    • Principal Investigator
      KUME Akihiro
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  造血細胞の遺伝子操作Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Jichi Medical University
  •  Self Renew and Cell Differentiation in Hemopoietic System

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
      Kumamoto University
  •  Development of the method for chromosomal site-specific integration of transgenes using AAV and its application to hematopoietic cellsPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Establishment of a producer cell line for adeno-associated virus vector using a novel system regulating nuclear protein

    • Principal Investigator
      URABE Masashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical School
  •  造血幹細胞を標的とした遺伝子治療のための新規選択的増幅遺伝子の開発Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  がん遺伝子治療への応用を目指したアデノ随伴ウイルスペクターシステムの開発Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  遺伝的素因と環境因子の相互作用による神経細胞死

    • Principal Investigator
      水野 美邦
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Juntendo University
  •  Development of a novel regulatory gene for in vivo & in vitro expansion of transduced hematopoietic stem cellssPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Development of GFP-tagged retrovirus vectors for gene therapy

    • Principal Investigator
      KUME Akihiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Jichi Medical School
  •  外因による脳神経細胞死のモデルとその応用

    • Principal Investigator
      太田 茂
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  遺伝子導入造血幹細胞を体内で選択的に増幅させるための新しい制御遺伝子の開発Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  アデノ随伴ウイルスベクター系の開発と新規自殺遺伝子を用いた細胞制御法への応用Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  Development of a novel gene therapy technology for site-specific integration of large-sized genesPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  造血幹細胞への遺伝子導入のためのレトロウイルスベクター産生システムの改良Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  細胞接着・転移におけるCas/Fakの相互作用

    • Principal Investigator
      堺 隆一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  サイトカイン補充遺伝子療法のための自殺遺伝子を介した細胞レベルでの調節法の開発Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Jichi Medical University
  •  細胞がん化におけるP130^<cas>の役割

    • Principal Investigator
      堺 隆一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Jichi Medical University
  •  がんに対する細胞移植/遺伝子治療の基礎的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  毒素結合コロニー刺激因子の骨髄性白血病治療への応用に関する基礎的研究

    • Principal Investigator
      東絛 有伸
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Molecular Analysis of Maturation Arrest Mechanism of Myeloid Leukemogenesis

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Molecular study of hematopoiesis-supporting ability of C3H10T1/2 mouse embryo fibroblastsPrincipal Investigator

    • Principal Investigator
      OZAWA Keiya
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  がんに対する細胞移植/遺伝子治療の基礎的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  骨髄移植後に出現するT細胞分画のPCRと温度勾配ゲル電気泳動法によるクローン解析

    • Principal Investigator
      小林 幸夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  レトロウイルスベクター系を用いた腫瘍細胞ターゲッティング法の開発:癌・白血病の遺伝子治療にむけたレトロウイルスベクターへの悪性リンパ腫特定細胞親和性の賦与

    • Principal Investigator
      谷 憲三朗
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  がんに対する細胞移植/遺伝子治療の基礎的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  レトロウイルスベクター系を用いた造血幹細胞ターゲッティング法の開発:血液疾患における遺伝子治療にむけたレトロウイルスへの特定細胞親和性の賦与

    • Principal Investigator
      谷 憲三朗
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  種々の変異体を用いたSCFの構造と機能の解析

    • Principal Investigator
      東條 有伸
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  抗原受容体遺伝子のトランス再構成に対する免疫不全状態の影響とその病態生理学的意義

    • Principal Investigator
      小林 幸夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  自己造血幹細胞移植におけるがん治療の基礎的臨床的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  顆粒球コロニ-刺激因子(GーCSF)のレセプタ-結合ドメインの検索とその意義Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  HSV_1ーTK遺伝子を用いた細胞機能抑制法の応用:GーCSFの生体内作用の研究ならびに遺伝子治療法への応用

    • Principal Investigator
      谷 憲三朗
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Novel Hematopoietic Factors Produced by Human Undifferentiated Leukemia Cell Lines. and Their Biological Significance

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  ヒトピルビン酸キナ-ゼcDNAを用いた遺伝子治療法の基礎的研究

    • Principal Investigator
      谷 憲三朗
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  赤芽球系細胞の増殖分化におけるp53がん抑制遺伝子の機能の解析

    • Principal Investigator
      東篠 有伸
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  骨髄ストロ-マ細胞による造血因子産生とその発現調節機構に関する研究Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  B19パルボウイルス(ヒトDNAウイルス)による造血障害の遺伝子解析Principal Investigator

    • Principal Investigator
      小澤 敬也
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  ヒト顆粒玉コロニ-刺激因子相補性DNA発現線維芽細胞を用いた遺伝子治療法の研究

    • Principal Investigator
      TANI Kenzaboro
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  自己造血幹細胞移植によるがん治療の基礎的臨床的研究

    • Principal Investigator
      浅野 茂隆
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Molecular Analysis of Acute Myelogenous Leukemia Cells Using G-CSF

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The Institute of Medical Science, The University of Tokyo (IMSUT)

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent Other

  • [Journal Article] Long-term outcome of patients with acquired chronic pure red cell aplasia (PRCA) following immunosuppressive therapy: a final report of the nationwide cohort study in 2004/2006 by the Japan PRCA collaborative study group.2015

    • Author(s)
      Hirokawa M, Sawada K, Fujishima N, Teramura M, Bessho M, Dan K, Tsurumi H, Nakao S, Urabe A, Fujisawa S, Yonemura Y, Kawano F, Oshimi K, Sugimoto K, Matsuda A, Karasawa M, Arai A, Komatsu N, Harigae H, Omine M, Ozawa K, Kurokawa M; PRCA Collaborative Study Group.
    • Journal Title

      Br J Haematol.

      Volume: in press Issue: 6 Pages: 879-886

    • DOI

      10.1111/bjh.13376

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-15K09468
  • [Journal Article] Distribution of serum erythropoietin levels in Japanese patients with myelodysplastic syndromes.2015

    • Author(s)
      Suzuki T, Oh I, Ohmine K, Meguro A, Mori M, Fujiwara S, Yamamoto C, Nagai T, Ozawa K.
    • Journal Title

      Int J Hematol.

      Volume: 101 Issue: 1 Pages: 32-36

    • DOI

      10.1007/s12185-014-1699-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-25461459
  • [Journal Article] Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex.2015

    • Author(s)
      Watakabe A, Ohtsuka M, Kinoshita M, Takaji M, Isa K, Mizukami H, Ozawa K, Isa T, and Yamamori T.
    • Journal Title

      Neurosci. Res.

      Volume: 93 Pages: 144-157

    • DOI

      10.1016/j.neures.2014.09.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430018, KAKENHI-PLANNED-26112008, KAKENHI-PROJECT-26221003
  • [Journal Article] The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies2015

    • Author(s)
      Tsukahara, T., Iwase, N., Kawakami, K., Iwasaki, M., Yamamoto, C., Ohmine, K., Uchibori, R., Teruya, T., Ido, H., Saga, Y., Urabe, M., Mizukami, H., Kume, A., Nakamura, M., Brentjens, R., and Ozawa, K.
    • Journal Title

      Gene Therapy

      Volume: 22 Issue: 2 Pages: 209-215

    • DOI

      10.1038/gt.2014.104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23241063, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
  • [Journal Article] Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance.2014

    • Author(s)
      Cui W, Mizukami H, Yanagisawa M, Aida T, Nomura M, Isomura Y, Takayanagi R, Ozawa K, Tanaka K, and Aizawa H.
    • Journal Title

      J. Neurosci.

      Volume: 34 Issue: 49 Pages: 16273-16285

    • DOI

      10.1523/jneurosci.1465-14.2014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26430008
  • [Journal Article] Leukemia cells directly phagocytose blood cells in AML-associated hemophagocytic lymphohistiocytosis: A case report and review of the literature.2014

    • Author(s)
      Hatano K, Nagai T, Matsuyama T, Sakaguchi , Fujiwara S.I, Oh I, Muroi K, and Ozawa K.
    • Journal Title

      Acta Haematol.

      Volume: 133 Issue: 1 Pages: 98-100

    • DOI

      10.1159/000360840

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25461435, KAKENHI-PROJECT-25461459
  • [Journal Article] The bone marrow hematopoietic microenvironment is impaired in iron-overloaded mice.2014

    • Author(s)
      Okabe H, Suzuki T, Uehara E, Ueda M, Nagai T, Ozawa K.
    • Journal Title

      Eur J Haematol.

      Volume: in Press Issue: 2 Pages: 118-128

    • DOI

      10.1111/ejh.12309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Journal Article] IL-21 is not necessary for anti-lymphoma effects of T cells expressing second-generation CD19-specific chimeric antigen receptors in a xenograft mouse model.2014

    • Author(s)
      Yamamoto C, Tsukahara T, Omine K, Teruya T, Ido H, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
    • Journal Title

      Jichi Medical University Journal

      Volume: 36 Pages: 23-31

    • NAID

      120006408261

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Journal Article] Intrathecal administration of high-titer cytomegalovirus immunoglobulin for cytomegalovirus meningitis.2014

    • Author(s)
      Fujiwara S, Muroi K, Tatara R, Ohmine K, Matsuyama T, Mori M, Nagai T, Ozawa K.
    • Journal Title

      Case Rep Hematol.

      Volume: 2014 Pages: 1-3

    • DOI

      10.1155/2014/272458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-26430168
  • [Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014

    • Author(s)
      Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey T, Suzuki M, Ichimura K, Ozawa K
    • Journal Title

      Cancer Science

      Volume: 105 Issue: 1 Pages: 72-80

    • DOI

      10.1111/cas.12315

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24592594, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-25461460
  • [Journal Article] Cancer gene therapy using mesenchymal stem cells.2014

    • Author(s)
      Uchibori R, Tsukahara T, Ohmine K, Ozawa K.
    • Journal Title

      Int J Hematol.

      Volume: 99 Issue: 4 Pages: 377-82

    • DOI

      10.1007/s12185-014-1537-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
  • [Journal Article] Production of functional coagulation factor VIII from iPSCs using a lentiviral vector2014

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y.
    • Journal Title

      Haemophilia

      Volume: 20 Issue: 1

    • DOI

      10.1111/hae.12311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Mechanisms of resistance to azacitidine in human leukemia cell lines.2014

    • Author(s)
      Sripayap P, Nagai T, Uesawa M, Kobayashi H, Tsukahara T, Ohmine K, Muroi K, Ozawa K.
    • Journal Title

      Exp Hematol.

      Volume: 42 Issue: 4 Pages: 294-306

    • DOI

      10.1016/j.exphem.2013.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25461435, KAKENHI-PROJECT-26430168
  • [Journal Article] The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals.2014

    • Author(s)
      Mimuro J, Mizukami H, Shima M, Matsushita T, Taki M, Muto S, Higasa S, Sakai M, Ohmori T, Madoiwa S, Ozawa K, and Sakata Y.
    • Journal Title

      J. Med. Virol.

      Volume: 86 Issue: 11 Pages: 1990-1997

    • DOI

      10.1002/jmv.23818

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430, KAKENHI-PROJECT-25461460
  • [Journal Article] Minimizing the inhibitory effect of neutralizing antibody for efficient gene expression in the liver with adeno-associated virus 8 vectors.2013

    • Author(s)
      Mimuro J, Mizukami H, Hishikawa S, Ikemoto T, Ishiwata A, Sakata A, Ohmori T, Madoiwa S, Ono F, Ozawa K, and Sakata Y
    • Journal Title

      Mol Ther

      Volume: 21 Issue: 2 Pages: 318-323

    • DOI

      10.1038/mt.2012.258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study.2013

    • Author(s)
      Muroi K, Miyamura K, Ohashi K, Murata M, Eto T, Kobayashi N, Taniguchi S, Imamura M, Ando K, Kato S, Mori T, Teshima T, Mori M, Ozawa K.
    • Journal Title

      Int J Hematol.

      Volume: 98 Issue: 2 Pages: 206-213

    • DOI

      10.1007/s12185-013-1399-4

    • NAID

      10031194736

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590686, KAKENHI-PROJECT-23591415, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25670443
  • [Journal Article] Suppression of lymph node and lung metastases of endometrial cancer by muscle-mediated expression of soluble VEGF receptor-32013

    • Author(s)
      Takahashi K, Mizukami H, Saga Y, Takei Y, Urabe M, Kume A, Machida S, Fujiwara H, Suzuki M, Ozawa K
    • Journal Title

      Cancer Science

      Volume: 104 Issue: 8 Pages: 1107-1111

    • DOI

      10.1111/cas.12184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25462606
  • [Journal Article] Overexpression of factor VII ameliorates bleeding diathesis of factor VIII-deficient mice with inhibitors.2013

    • Author(s)
      Yasumoto A, Madoiwa S, Kashiwakura Y, Ishiwata A, Ohmori T, Mizukami H. Ozawa K, Sakata Y, and Mimuro J.
    • Journal Title

      Thromb. Res.

      Volume: 131 Issue: 5 Pages: 444-449

    • DOI

      10.1016/j.thromres.2013.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013

    • Author(s)
      Tsukahara T, Ohmine K, Yamamoto C, Uchibori R, Ido H, Teruya T, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 438 Issue: 1 Pages: 84-89

    • DOI

      10.1016/j.bbrc.2013.07.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
  • [Journal Article] NF-κB activity regulates mesenchymal stem cell accumulation at tumor sites.2013

    • Author(s)
      Uchibori R, Tsukahara T, Mizuguchi H, Saga Y, Urabe M, Mizukami H, Kume A, Ozawa K
    • Journal Title

      Cancer Research

      Volume: 73 Issue: 1 Pages: 364-372

    • DOI

      10.1158/0008-5472.can-12-0088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
  • [Journal Article] Downregulation of indoleamine-2, 3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation.2012

    • Author(s)
      Sato N, Saga Y, Mizukami H, Wang D, Takahashi S, Nonaka H, Fujiwara H, Takei Y, Machida S, Takikawa O, Ozawa K, Suzuki M.
    • Journal Title

      Oncol Rep.

      Volume: 28 Pages: 1574-1578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659493
  • [Journal Article] Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy2012

    • Author(s)
      Yagi, H., Sanechika, S., Ichinose, H., Sumi-Ichinose, C., Mizukami, H., Urabe, M., Ozawa, K., and Kume, A.
    • Journal Title

      Neuroreport

      Volume: 23 Issue: 1 Pages: 30-34

    • DOI

      10.1097/wnr.0b013e32834e3a87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500305, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247
  • [Journal Article] Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats2012

    • Author(s)
      Ogura M, Urabe M, Akimoto T, Onishi A, Ito C, Ito T, Tsukahara T, Mizukami H, Kume A, Muto S, Kusano E, and Ozawa K.
    • Journal Title

      Gene Ther

      Volume: 19巻 Issue: 5 Pages: 476-82

    • DOI

      10.1038/gt.2011.183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-21591248, KAKENHI-PROJECT-22700923, KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247
  • [Journal Article] Intra-articular injection of mesenchymal stem cells expressing coagulation factorameliorates hemophilic arthropathy in factor VIII-deficient mice.2012

    • Author(s)
      Kashiwakura, Y
    • Journal Title

      J Thromb Haemost.

      Volume: 10(9) Issue: 9 Pages: 1802-1813

    • DOI

      10.1111/j.1538-7836.2012.04851.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy2012

    • Author(s)
      Wang, D.
    • Journal Title

      Int J Oncol

      Volume: 40 Issue: 4 Pages: 929-34

    • DOI

      10.3892/ijo.2011.1295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-21590353, KAKENHI-PROJECT-23659493
  • [Journal Article] Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.2012

    • Author(s)
      Sato, N.
    • Journal Title

      Oncol Rep.

      Volume: 27 Pages: 1336-1340

    • DOI

      10.3892/or.2012.1626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247
  • [Journal Article] Morphologic analysis in myelodysplastic syndromes with del(5q) treated with lenalidomide. A Japanese multiinstitutional study2012

    • Author(s)
      Matsuda A, Taniwaki M, Jinnai I, Harada H, Watanabe M, Suzuki K, Yanagita S, Suzuki T, Yoshida Y, Kimura A, Tsudo M, Tohyama K, Takatoku M, Ozawa K
    • Journal Title

      Leuk Res

      Volume: (in press) Issue: 5 Pages: 575-580

    • DOI

      10.1016/j.leukres.2011.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PUBLICLY-23118518, KAKENHI-PROJECT-23590696, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24591398
  • [Journal Article] Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy2012

    • Author(s)
      Yagi H, Sanechika S, Ichinose H, Sumi-Ichinose C, Mizukami H, Urabe M, Ozawa K, Kume A
    • Journal Title

      Neuroreport

      Volume: 4巻 Pages: 30-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Vincristine potentiates the anti- proliferative effect of an aurora kinase inhibitor, VE-465, in myeloid leukemia cells2011

    • Author(s)
      Yoshida K, Nagai T, Ohmine K, Uesawa M, Sripayap P, Ishida Y, and Ozawa K.
    • Journal Title

      Biochem Pharmacol

      Volume: 82 Issue: 12 Pages: 1884-1890

    • DOI

      10.1016/j.bcp.2011.09.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659493
  • [Journal Article] Selective optical control of synaptic transmission in the subcorticalvisual pathway by activation of viral vector-expressed halorhodopsin2011

    • Author(s)
      Kaneda K, Kasahara H, Matsui R, Katoh T, Mizukami H, Ozawa K, Watanabe D, Isa T
    • Journal Title

      PLoSONE

      Volume: 6 Issue: 4 Pages: 18452-18452

    • DOI

      10.1371/journal.pone.0018452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650064, KAKENHI-PROJECT-22700419, KAKENHI-PROJECT-23659493
  • [Journal Article] Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation2011

    • Author(s)
      Tatara R, Ozak K., Kikuchi Y, Hatanaka K, Oh I, Meguro A, Matsu H, Sato K, and Ozawa K
    • Journal Title

      Cytotherapy

      Volume: 13巻 Pages: 686-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Lack of IL-21 signal attenuates graft-versus-leukemia effect in the absence of CD8 T-cells2011

    • Author(s)
      Meguro A, Ozaki K, Hatanaka K, Oh I, Sudo K, Ohmori T, Matsu H, Tatara., Sato K, Sakata Y, Nakae S, Leonard W J, and Ozawa K
    • Journal Title

      Bone Marrow Transplant

      Volume: 46巻 Issue: 12 Pages: 1557-1565

    • DOI

      10.1038/bmt.2010.342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-21591247, KAKENHI-PROJECT-22790918, KAKENHI-PROJECT-23659493
  • [Journal Article] Development of a mouse model for lymph node metastasis with endometrial cancer2011

    • Author(s)
      Takahashi K, Saga Y, Mizukami H, Takei Y, Urabe M, Kume A, Suzuki M, and Ozawa K
    • Journal Title

      Cancer Sci

      Volume: 102巻 Issue: 12 Pages: 2272-7

    • DOI

      10.1111/j.1349-7006.2011.02099.x

    • NAID

      10030246395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-23659493
  • [Journal Article] Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation2011

    • Author(s)
      Tatara R, Ozaki K, Kikuchi Y, Hatanaka K, Oh I, Meguro A, Matsu H, Sato K, Ozawa K.
    • Journal Title

      Cytotherapy

      Volume: 13 Issue: 6 Pages: 686-694

    • DOI

      10.3109/14653249.2010.542456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790918, KAKENHI-PROJECT-23659493
  • [Journal Article] Complete restoration of phenylalanine oxidation in phenylketonuria mouse by a self-complementary adeno-associated virus vector2011

    • Author(s)
      Yagi H, Ogura T, Mizukami H, Urabe M, Hamada H, Yoshikawa H, Ozawa K and Kume A
    • Journal Title

      J. Gene Med

      Volume: 13巻 Issue: 2 Pages: 114-122

    • DOI

      10.1002/jgm.1543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296, KAKENHI-PROJECT-22390309, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-23659770
  • [Journal Article] A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease2010

    • Author(s)
      Muramatsu S, Fujimoto K, Kato S, Mizukami H, Asari S, Ikeguchi K, Kawakami T, Urabe M, Kume A, Sato T, Watanabe E, Ozawa K, Nakano I
    • Journal Title

      Mol Ther

      Volume: 18巻 Pages: 1731-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Altered effector CD4+T cell function in IL-21R-/-CD4+T cell-mediated graft-versus-host disease2010

    • Author(s)
      Oh I, Ozaki K, Meguro A, Hatanaka K, Kadowaki M, Matsu H, Tatara R, Sato K, Iwakura Y, Nakae S, Sudo K, Teshima T, Leonard W J and Ozawa K
    • Journal Title

      J. Immunol

      Volume: 185巻 Pages: 1920-1926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines2010

    • Author(s)
      Kobayashi M, Murakami T, Uchibori R, Chun NA, Kobayashi E, Morita T, Ozawa K.
    • Journal Title

      J Urol

      Volume: 183巻 Pages: 2029-2035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] IL-21 is critical for GVHD in a mouse model2010

    • Author(s)
      Meguro A, Ozaki K, Oh I, Hatanaka K, Matsu H, Tatara R, Sato. K, Leonard W J and Ozawa K
    • Journal Title

      Bone Marrow Transplant

      Volume: 45巻 Pages: 723-729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Mutant Macaque Factor IX T262A : A Tool for Hemophilia B Gene Therapy Studies in Macaques2010

    • Author(s)
      Ishiwata A, Mimuro J, Mizukami H, Kashiwakura Y, Yasumoto A, Sakata A, Ohmori T, Madoiwa S, Ono F, Shima M, Yoshioka A, Ozawa K, Sakata Y
    • Journal Title

      Thromb Res

      Volume: 125巻 Pages: 533-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Gene therapy for Parkinson's disease. Strategies for the local production of dopamine2010

    • Author(s)
      Muramatsu S, Asari S, Fujimoto K, Ozawa K and Nakamo I.
    • Journal Title

      Gene Therapy & Regulation

      Volume: 5巻 Pages: 57-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Scalable purification of adeno-associated virus serotype 1(AAV1) and AAV8 vectors, using dual ion-exchange adsorptive membranes2009

    • Author(s)
      Okada T, Nonaka-Sarukawa M, Uchibori R, Kinoshita K, Hayashita-Kinoh H, Nitahara-Kasahara Y, Takeda S, and Ozawa K
    • Journal Title

      Hum. Gene Ther

      Volume: 20巻 Pages: 1013-1021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Generation of adeno-associated virus vector enabling functional expression of oxytocin receptor and fluorescence marker genes using the human eIF4G internal ribosome entry site element2009

    • Author(s)
      Sato K, Date S, Aoyagi Y, Kasahara Y, Nawa A, Mizukami H, Hidema S, Ozawa K, Nishimori K
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 73巻 Pages: 2145-2148

    • NAID

      10027546295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] A convenient enzyme-linked immunosorbent assay for rapid screeningof anti-adeno-associated virus neutralizing antibodies2009

    • Author(s)
      Ito T, Yamamoto S, Hayashi T, Kodera M, Mizukami H, Ozawa K, Muramatsu S.
    • Journal Title

      Ann. Clin. Biochem

      Volume: 46巻 Pages: 508-510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.2009

    • Author(s)
      Uchibori, R., Okada, T., Ito, T., Urabe, M., Mizukami, H., Kume, A., Ozawa, K.
    • Journal Title

      J. Gene Med. 11

      Pages: 373-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.2009

    • Author(s)
      Uchibori, R., Okada, T., Ito, T., Urabe, M., Mizukami, H., Kume, A., and Ozawa, K.
    • Journal Title

      J. Gene Med. 11

      Pages: 373-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma.2009

    • Author(s)
      Hatano, K., Kikuchi, J., Takatoku, M., Shimizu, R., Wada, T., Ueda, M., Nobuyoshi, M., Oh, I., Sato, K., Suzuki, T., Ozaki, K., Mori, M., Nagai, T., Muroi, K., Kano, Y,. Furukawa, Y., and Ozawa, K.
    • Journal Title

      Oncogene 28(2)

      Pages: 231-242

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Scalable purification of adeno-associated virus serotype 1 (AAV1) and AAV8 vectors, using dual ion-exchange adsorptive membranes.2009

    • Author(s)
      Okada, T., Nonaka-Sarukawa, M., Uchibori, R., Kinoshita, K., Hayashita-Kinoh, H., Nitahara-Kasahara, Y., Takeda, S., Ozawa, K.
    • Journal Title

      Hum. Gene Ther. 20(9)

      Pages: 1013-1021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Generation of adeno-associated virus vector enabling functional expression of oxytocin receptor and fluorescence marker genes using the human eIF4G internal ribosome entry site element.2009

    • Author(s)
      Sato, K., Date, S., Aoyagi, Y., Kasahara, Y., Nawa, A., Mizukami, H., Hidema, S., Ozawa, K., Nishimori, K.
    • Journal Title

      Biosci. Biotechnol. Biochem. 73(9)

      Pages: 2145-2148

    • NAID

      10027546295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Systemic delivery of IL-10 by an AAV vector prevents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat2009

    • Author(s)
      Nomoto T, Okada T, Shimazaki K, Yoshioka T, Nonaka-Sarukawa M, Ito T, Takeuchi K, Katsura K I, Mizukami H, Kume A, Ookawara S, Ikeda U, Katayama Y, and Ozawa K
    • Journal Title

      Gene Ther

      Volume: 16巻 Pages: 383-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies.2009

    • Author(s)
      Ito, T., Yamamoto, S., Hayashi, T., Kodera, M., Mizukami, H., Ozawa, K., Muramatsu, S.
    • Journal Title

      Ann. Clin. Biochem. 46(Pt6)

      Pages: 508-510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Systemic delivery of IL-10 by an AAV vector prevents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat.2009

    • Author(s)
      Kume, A., Ookawara, S., Ikeda, U., Katayama, Y., Ozawa, K.
    • Journal Title

      Gene Ther. 16(3)

      Pages: 383-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice2009

    • Author(s)
      Ishiwata A, Mimuro J, Mizukami H, Kashiwakura Y, Takano K, Ohmori T, Madoiwa S, Ozawa K and Sakata Y
    • Journal Title

      J. Gene Med

      Volume: 11巻 Pages: 1020-1029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Cotransplantation with MSCs improves engraftment of HSCs after autologous intra-bone marrow transplantation in nonhuman primates2009

    • Author(s)
      Masuda S, Ageyama N, Shibata H, Obara Y, Ikeda T, Takeuchi K, Ueda Y, Ozawa K., Hanazono Y
    • Journal Title

      Exp. Hematol

      Volume: 37巻 Pages: 1250-1257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy2009

    • Author(s)
      Uchibori R, Okada T, Ito T, Mizukami H, Kume A and Ozawa, K
    • Journal Title

      J. Gene Med

      Volume: 11巻 Pages: 373-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390296
  • [Journal Article] Vector-producing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy. Front.2008

    • Author(s)
      Okada, T. and Ozawa, K.
    • Journal Title

      Biosci. 13

      Pages: 1887-1891

    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species.2008

    • Author(s)
      Yoshida, K., Kirito, K., Yongzhen, H., Ozawa, K., Kaushansky, K., and Komatsu, N.
    • Journal Title

      Int J Hematol. 88(1)

      Pages: 43-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Protection against aminoglycoside-induced ototoxicity by regulated AAV vector-mediated GDNF gene transfer into the cochlea.2008

    • Author(s)
      Liu, Y., Okada, T., Shimazaki, K., Sheykholeslami, K., Nomoto, T., Muramatsu, S., Mizukami, H., Kume, A., Xiao, S., Ichimura, K., Ozawa, K.
    • Journal Title

      Mol. Ther. 16(3)

      Pages: 474-480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] High-resolution analysis of chromosome copy number alterations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, unspecified, with single nucleotide polymorphism-typing microarrays2008

    • Author(s)
      Fujiwara SI, Yamashita Y, Nakamura N, Choi YL, Ueno T, Watanabe H, Kurashina K, Soda M, Enomoto M, Hatanaka H, Takada S, Abe M, Ozawa K, Mano H.
    • Journal Title

      Leukemia 22

      Pages: 1891-1898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019060
  • [Journal Article] High-resolution analysis of chromosome copy number alterations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma, unspecified, with single nucleotide polymorphism-typing microarrays.2008

    • Author(s)
      Fujiwara, S., Yamashita, Y., Nakamura, N., Choi, Y.L., Ueno, T., Watanabe, H., Kurashina, K., Soda, M., Enomoto, M., Hatanaka, H., Takada, S., Abe, M., Ozawa, K., and Mano, H.
    • Journal Title

      Leukemia 22(10)

      Pages: 1891-1898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Hemin reduces cellular sensitivity to imatinib and anthracyclins via Nrf2. J. Cell.2008

    • Author(s)
      Nagai, T., Kikuchi, S., Ohmine, K., Miyoshi, T., Nakamura, M., Kondo, T., Furuyama, K., Komatsu, N., and Ozawa, K.
    • Journal Title

      Biochem. 104(2)

      Pages: 680-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

    • Author(s)
      Ozawa, K., Sato, K., Oh, I., Ozaki, K., Uchibori, R., Obara, Y., Kikuchi, Y., Ito, T., Okada, T., Urabe, M., Mizukami, H., and Kume, A.
    • Journal Title

      J. Autoimmun. 30(3)

      Pages: 121-127

    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Vectorproducing tumor-tracking multipotent mesenchymal stromal cells for suicide cancer gene therapy.2008

    • Author(s)
      Okada, T. and Ozawa, K.
    • Journal Title

      Front. Biosci. 13

      Pages: 1887-1891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Overexpression of PTEN in ovarian cancer cells suppresses i. p. dissemination and extends survival in mice.2008

    • Author(s)
      Takei, Y., Saga, Y., Mizukami, H., Takayama, T., Ohwada, M., Ozawa, K., Suzuki, M.
    • Journal Title

      Mol. Cancer. Ther. 7(3)

      Pages: 704-711

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Adeno-associated virus vector-mediated systemic interleukin-10 expression ameliorates hypertensive organ damage in Dahl salt-sensitive rats.2008

    • Author(s)
      Nonaka-Sarukawa, M., Okada, T., Ito, T., Yamamoto, K., Yoshioka, T., Nomoto, T., Hojo, Y., Shimpo, M., Urabe, M., Mizukami, H., Kume, A., Ikeda, U., Shimada, K., Ozawa, K.
    • Journal Title

      J Gene Med. 10(4)

      Pages: 368-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

    • Author(s)
      Ozawa, K., Sato, K., Oh, I., Ozaki, K,. Uchibori, R., Obara, Y., Kikuchi, Y., Ito, T.,Okada, T., Urabe, M., Mizukami, H., and Kume, A.
    • Journal Title

      J. Autoimmun. 30(3)

      Pages: 121-127

    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Adeno-associated virus vector-mediated systemic interleukin-10 expression ameliorates hypertensive organ damage in Dahl salt-sensitive rats.2008

    • Author(s)
      Nonaka-Sarukawa, M., Okada, T., Ito, T., Yamamoto, K., Yoshioka, T., Nomoto, T., Hojo, Y., Shimpo, M., Urabe, M., Mizukami, H., Kume, A., Ikeda, U., Shimada, K., and Ozawa, K.
    • Journal Title

      J Gene Med. 10(4)

      Pages: 368-374

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Cell and gene therapy using mesenchymal stem cells (MSCs).2008

    • Author(s)
      Ozawa, K.
    • Journal Title

      J. Autoimmun. 30

      Pages: 121-127

    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Cell and gene therapy using mesenchymal stem cells(MSCs).2008

    • Author(s)
      Ozawa, K.
    • Journal Title

      J.Autoimmun. 30

      Pages: 121-127

    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Prevention of diabetic retinopathy by intraocular soluble Flt-1 gene transfer in a spontaneously diabetic rat model.2007

    • Author(s)
      Ideno, J., Mizukami, H., Kakehashi, A., Saito, Y., Okada, T., Urabe, M., Kume, A., Kuroki, M., Kawakami, M., Ishibashi, S., Ozawa, K.
    • Journal Title

      Int. J. Mol. Med. 19

      Pages: 75-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Cloning and characterization of a human BCR/ABL-positive cell line, K562/RR, resistant to the farnesyltransferase nhibition by tipifarnib.2007

    • Author(s)
      Miyoshi, T., Nagai, T., Kikuchi, S., Ohmine, K., Nakamura, M., Hanafusa, T., Komatsu, N., and Ozawa, K.
    • Journal Title

      Exp. Hematol. 35

      Pages: 1358-1365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] E2F-6 suppresses growth-associated apoptosis of human hematopoieticprogenitor cells by counteracting proapoptotic activity of E2F-1.2007

    • Author(s)
      Kikuchi, J., Shimizu, R., Wada, T., Ando, H., Nakamura, M., Ozawa, K., and Furukawa, Y.
    • Journal Title

      Stem Cells 25

      Pages: 2439-2447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Adeno-associated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.2007

    • Author(s)
      Ito, T., Okada, T., Mimuro, J., Miyashita, H., Uchibori, R., Urabe, M., Mizukami, H., Kume, A., Takahashi, M., Ikeda, U., Sakata, Y., Shimada, K., Ozawa, K.
    • Journal Title

      Hypertension 50

      Pages: 531-536

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Active FKHRL1 overcomes imatinib resistance in chronic myelogenous leukemia-derived cell lines via the production of tumor necrosis factor-related apoptosisinducing ligand.2007

    • Author(s)
      Kikuchi, S., Nagai, T., Kunitama, M., Kirito, K., Ozawa, K., and Komatsu, N.
    • Journal Title

      Cancer Sci. 98

      Pages: 1949-1958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Transforming activity of purinergic receptor P2Y, G protein coupled, revealed by retroviral expression screening.2007

    • Author(s)
      Fujiwara, S., Yamashita, Y., Choi, Y.L., Watanabe, H., Kurashina, K., Soda, M., Enomoto, M., Hatanaka, H., Takada, S., Ozawa, K., Mano, H.
    • Journal Title

      Leuk. Lymphoma. 48

      Pages: 978-986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Nitric oxide plays a critical role in suppression of T cell proliferation by mesenchymal stem cells.2007

    • Author(s)
      Sato, K., Ozaki, K., Oh, I., Meguro, A., Hatanaka, K., Nagai, T., Muroi, K., Ozawa, K.
    • Journal Title

      Blood 109

      Pages: 228-234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Mechanisms of immunomodulation by mesenchymal stem cells.2007

    • Author(s)
      Ozaki, K., Sato, K., Oh, I., Meguro, A., Tatara, R., Muroi, K., and Ozawa, K.
    • Journal Title

      Int. J. Hematol. 86

      Pages: 5-7

    • NAID

      10018515331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Screening of genes responsible for differentiation of mouse mesenchymal stromal cells by DNA microarray analysis of C3H10T1/2 and C3H10T1/2 -derived cell lines.2007

    • Author(s)
      Oh, I., Ozaki, K., Miyazato, A., Sato, K., Meguro, A., Muroi, K., N agai, T., Mano, H., and Ozawa, K.
    • Journal Title

      Cytotherapy 9

      Pages: 80-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Interferon-gamma and NF-kappaB mediate nitric oxide production by mesenchymal stromal cells.2007

    • Author(s)
      Oh, T., Ozaki, K., Sato, K., Meguro, A., Tatara, R., Hatanaka, K., Nagai, T., Muroi, K., Ozawa, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 355

      Pages: 956-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Journal Article] Interferon-gamma and NF-kappaB mediate nitric oxide production by mesenchymal stromal cells.2007

    • Author(s)
      Oh, I., Ozaki, K., Sato, K., Meguro, A., Tatara, R., Hatanaka, K., Nagai, T., Muroi, K., Ozawa, K.
    • Journal Title

      Biochem. Biophys. Res. Commun. 355

      Pages: 956-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening2007

    • Author(s)
      Fujiwara S, Yamashita Y, Choi YL, Watanabe H, Kurashina K, Soda M, Enomoto M, Hatanaka H, Takada S, Ozawa K, Mano H.
    • Journal Title

      Leuk Lymphoma 48

      Pages: 978-986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019060
  • [Journal Article] Interleukin-10 expression mediated by an adeno-associated virus vector prevents monocrotaline-induced pulmonary arterial hypertension in rats.2007

    • Author(s)
      Ito, T., Okada, T., Miyashita, H., Nomoto, T., Nonaka-Sarukawa, M., Uchibori, R., Maeda, Y., Urabe, M., Mizukami, H., Kume, A., Takahashi, M., Ikeda, U., Shimada, K., Ozawa, K.
    • Journal Title

      Circ. Res. 101

      Pages: 734-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.2006

    • Author(s)
      Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., Urabe, M., Kume, A., Hamada, H., Yoshikawa, H., Sakata, Y., Ozawa, K.
    • Journal Title

      Gene Med. 8

      Pages: 990-997

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.2006

    • Author(s)
      Okada, T., Uchibori, R., Iwata-Okada, M., Takahashi, M., Nomoto, T., Nonaka-Sarukawa, M., Ito, T., Liu, Y., Mizukami, H., Kume, A., Kobayashi, E., Ozawa, K.
    • Journal Title

      Mol. Ther. 13

      Pages: 738-746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Adipose Tissue as a Novel Target for In Vivo Gene Transfer by Using Adeno-Associated Virus Vectors.2006

    • Author(s)
      Mizukami H, Mimuro J, Ogura T, Okada T, Urabe M, Kume A, Sakata Y, Ozawa K
    • Journal Title

      Hum Gene Ther 17(9)

      Pages: 921-928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] Suppression of ovarian cancer by muscle-mediated expression of soluble VEGFR-1/Flt-1 using adeno-associated virus serotype 1-derived vector.2006

    • Author(s)
      Takei, Y., Mizukami, H., Saga, Y., Yoshimura, I., Hasumi, Y., Takayama, T., Kohno, T., Matsushita, T., Okada, T., Kume, A., Suzuki, M., Ozawa, K.
    • Journal Title

      Int. J. Cancer 120

      Pages: 278-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression.2006

    • Author(s)
      Urabe, M., Xin, K.Q., Obara, Y., Nakakura, T., Mizukami, H., Kume, A., Okuda, K., Ozawa, K.
    • Journal Title

      Mol. Ther. 13

      Pages: 823-828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.2006

    • Author(s)
      Urabe M, Nakakura T, Xin KQ, Obara Y, Mizukami H, Kume A, Kotin RM, Ozawa K.
    • Journal Title

      J.Virol. 80

      Pages: 1874-1885

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.2006

    • Author(s)
      Okada, T., Uchibori, R., Iwata-Okada, M., Takahashi, M., Nomoto, T., Nonaka-Sarukawa, M., Ito, T., Liu, Y., Mizukami, H., Kume, A., Kobayashi, E., Ozawa, K.
    • Journal Title

      Mol.Ther. 13

      Pages: 738-746

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease.2006

    • Author(s)
      Li, X.G., Okada, T., Kodera, M., Nara, Y., Takino, N., Muramatsu, C., Ikeguchi, K., Urano, F., Ichinose, H., Metzger, D., Chambon, P., Nakano, I., Ozawa, K., Muramatsu, S.
    • Journal Title

      Mol. Ther. 13

      Pages: 160-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease2006

    • Author(s)
      Li, X.G., Okada, T., Kodera, M., Nara, Y., Takino, N., Muramatsu, C., Ikeguchi, K., Urano, F., Ichinose, H., Metzger, D., Chambon, P., Nakano, I., Ozawa, K., Muramatsu, S.
    • Journal Title

      Mol.Ther. 13

      Pages: 160-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] rAAV-mediated shRNA ameliorated 6 neuropathology in Huntington disease model mouse. Biochem.2006

    • Author(s)
      Machida, Y., Okada, T., Kurosawa, M., Oyama, F., Ozawa, K., Nukina, N.
    • Journal Title

      Biophys. Res. Commun. 343

      Pages: 190-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.2006

    • Author(s)
      Urabe, M., Nakakura, T., Xin, K.Q., Obara, Y., Mizukami, H., Kume, A., Kotin, R.M., Ozawa, K.
    • Journal Title

      J. Virol. 80

      Pages: 1874-1885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.2006

    • Author(s)
      Ogura T, Mizukami H, Mimuro J, Okada T, Matsushita T, Urabe M, Kume A, Hamada H, Yoshikawa H, Sakata Y, Ozawa K
    • Journal Title

      J Gene Med 8(8)

      Pages: 990-997

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors.2006

    • Author(s)
      Mizukami, H., Mimuro, J., Ogura, T., Okada, T., Urabe, M., Kume, A., Sakata, Y., Ozawa, K.
    • Journal Title

      Hum. Gene Ther. 17

      Pages: 921-928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression.2006

    • Author(s)
      Urabe, M., Xin, K.Q., Obara, Y., Nakakura, T., Mizukami, H., Kume, A., Okuda, K., Ozawa, K.
    • Journal Title

      Mol.Ther. 13

      Pages: 823-828

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse.2006

    • Author(s)
      Machida, Y., Okada, T., Kurosawa, M., Oyama, F., Ozawa, K., Nukina, N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 343

      Pages: 190-197

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Phenotype correction of hemophilia A mice with adeno-associated virus vectors carrying the B domain-deleted canine factor VIII gene.2006

    • Author(s)
      Ishiwata, A., Mimuro, J., Kashiwakura, Y., Niimura, M., Takano, K., Ohmori, T., Madoiwa, S., Mizukami, H., Okada, T., Naka, H., Yoshioka, A., Ozawa, K., Sakata, Y.
    • Journal Title

      Thromb. Res. 118

      Pages: 627-635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved.2005

    • Author(s)
      Sasaki, K., Inoue, M., Shibata, H., Ueda, Y., Muramatsu, S., Okada, T., Hasegawa, M., Ozawa, K., Hanazono, Y.
    • Journal Title

      Gene Ther. 12

      Pages: 203-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Development of new inbred transgenic strains of rats with LacZ or GFP.2005

    • Author(s)
      Inoue, H., Ohsawa, I., Murakami, T., Kimura, A., Hakamata, Y., Sato, Y., Kaneko, T., Takahashi, M., Okada, T., Ozawa, K., Francis, J., Leone, P., Kobayashi, E.
    • Journal Title

      Biochem.Biophys.Res.Commun. 329

      Pages: 288-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Repair of infarcted myocardium mediated by transplanted bone marrow-derived CD34^+ stem cells in a nonhuman primate model.2005

    • Author(s)
      Yoshioka, T., Ageyama, N., Shibata, H., Yasu, T., Misawa, Y., Takeuchi, K., Matsui, K., Yamamoto, K., Terao, K., Shimada, K., Ikeda, U., Ozawa, K., Hanazono, Y.
    • Journal Title

      Stem Cells 23

      Pages: 355-364

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] TEF, an anti-apoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down regulating expression of the common b chain of cytokine receptors.2005

    • Author(s)
      Inukai, T., Inaba, T., Dang, J., Kuribara, R., Ozawa, K., Miyajima, A., Wu, W., Look, A.T., Arinobu, Y., Iwasaki, H., Akashi, K., Kagami, K., Goi, K., Sugita, K., Nakazawa, S.
    • Journal Title

      Blood 105

      Pages: 4437-4444

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.2005

    • Author(s)
      Okada, T., Nomoto, T., Yoshioka, T., Nonaka-Sarukawa, M., Ito, T., Ogura, T., Iwata-Okada, M., Uchibori, R., Shimazaki, K., Mizukami, H., Kume, A., Ozawa, K.
    • Journal Title

      Hum.Gene Ther. 16

      Pages: 1212-1218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Transforming activity of the lymphotoxin-beta receptor revealed by expression screening.2005

    • Author(s)
      Fujiwara, S., Yamashita, Y., Choin Y.L., Wada, T., Kaneda, R., Takada, S., Maruyama, Y., Ozawa, K., Mano, H.
    • Journal Title

      Biochem.Biophys.Res.Commun. 338

      Pages: 1256-1262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector.2005

    • Author(s)
      Yokoo, N., Saito, T., Uesugi, M., Kobayashi, N., Xin, K.Q., Okuda, K., Mizukami, H., Ozawa, K., Koshino, T.
    • Journal Title

      Arthritis Rheum. 52

      Pages: 164-170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.2005

    • Author(s)
      Okada, T., Nomoto, T., Yoshioka, T., Nonaka-Sarukawa, M., Ito, T., Ogura, T., Iwata-Okada, M., Uchibori, R., Shimazaki, K., Mizukami, H., Kume, A., Ozawa, K.
    • Journal Title

      Hum. Gene Ther. 16

      Pages: 1212-1218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector.2005

    • Author(s)
      Liu, Y., Okada, T., Sheykholeslami, K., Shimazaki, K., Nomoto, T., Muramatsu, S., Kanazawa, T., Takeuchi, K., Ajalli, R., Mizukami, H., Kume, A., Ichimura, K., Ozawa, K.
    • Journal Title

      Mol. Ther. 12

      Pages: 725-733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector.2005

    • Author(s)
      Yokoo, N., Saito, T., Uesugi, M., Kobayashi, N., Xin, K.Q., Okuda, K., Mizukami, H., Ozawa, K., Koshino, T.
    • Journal Title

      Arthritis Rheum. 52

      Pages: 164-170

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Safe and efficient collection of cytokine-mobilized peripheral blood cells from cynomolgus monkeys (Macaca fascicularis) with human newborn-equivalent body weights.2005

    • Author(s)
      Ageyama, N., Hanazono, Y., Shibata, H., Ono, F., Ogawa, H., Nagashima, N., Ueda, Y., Yoshikawa, Y., Hasegawa, M., Ozawa, K., Terao, K.
    • Journal Title

      Exp.Anim. 54

      Pages: 421-428

    • NAID

      10016785510

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector.2005

    • Author(s)
      Liu, Y., Okada, T., Sheykholeslami, K., Shimazaki, K., Nomoto, T., Muramatsu, S., Kanazawa, T., Takeuchi, K., Ajalli, R., Mizukami, H., Kume, A., Ichimura, K., Ozawa, K.
    • Journal Title

      Mol.Ther. 12

      Pages: 725-733

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved.2005

    • Author(s)
      Sasaki, K., Inoue, M., Shibata, H., Ueda, Y., Muramatsu, S., Okada, T., Hasegawa, M., Ozawa, K., Hanazono, Y.
    • Journal Title

      Gene Ther. 12

      Pages: 203-210

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector.2005

    • Author(s)
      Hiraide, A., Yokoo, N., Xin, K.Q., Okuda, K., Mizukami, H., Ozawa, K., Saito, T.
    • Journal Title

      Hum.Gene Ther. 16

      Pages: 1413-1421

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Transforming activity of the lymphotoxin-beta receptor revealed by expression screening.2005

    • Author(s)
      Fujiwara, S., Yamashita, Y., Choin Y.L., Wada, T., Kaneda, R., Takada, S., Maruyama, Y., Ozawa, K., Mano, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 338

      Pages: 1256-1262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Journal Article] Hematopoietic microchimerism in sheep after in utero transplantation of cultured cynomolgus embryonic stem cells.2005

    • Author(s)
      Sasaki, K., Nagao, Y., Kitano, Y., Hasegawa, H., Shibata, H., Takatoku, M., Hayashi, H., Ozawa, K., Hanazono, Y.
    • Journal Title

      Transplantation 79

      Pages: 32-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis.2005

    • Author(s)
      Ishii, H., Inageta, T., Mimori, K., Saito, T., Sasaki, H., Isobe, M., Mori, M., Croce, C.M., Huebner, K., Ozawa, K., Furukawa, Y.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 102

      Pages: 9655-9660

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Topoisomerase inhibitors enhance the cytocidal effect of AAV-HSVtk/ganciclovir on head and neck cancer cells.2004

    • Author(s)
      Kanazawa, T., Mizukami, H., Nishino, H., Okada, T., Hanazono, Y., Kume, A., Kitamura, K., Ichimura, K., Ozawa, K.
    • Journal Title

      Int.J.Oncol. 25

      Pages: 729-735

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene.2004

    • Author(s)
      Hara T, Kume A, Hanazono Y, Mizukami H, Okada T, Tsurumi H, Moriwaki H, Ueda Y, Hasegawa M, Ozawa K
    • Journal Title

      Gene Ther 11(18)

      Pages: 1370-1377

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004

    • Author(s)
      Matsushita, T., Okada, T., Inaba, T., Mizukami, H., Ozawa, K., Colosi, P.
    • Journal Title

      J.Gen.Virol. 85

      Pages: 2209-2214

    • NAID

      110006452410

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Successful gene transfer using adeno-associated virus vectors into the kidney : comparison among adeno-associated virus serotype 1 to 5 vectors in vitro and in vivo.2004

    • Author(s)
      Takeda, S., Takahashi, M., Mizukami, H., Kobayashi, E., Takeuchi, K., Hakamata, Y., Kaneko, T., Yamamoto, H., Ito, C., Ozawa, K., Ishibashi, K., Matsuzaki, T., Takata, K., Asano, Y., Kusano, E.
    • Journal Title

      Nephron Exp.Nephrol. 96

      Pages: 119-126

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice.2004

    • Author(s)
      Mochizuki, S., Mizukami, H., Ogura, T., Kure, S., Ichinohe, A., Kojima, K., Matsubara, Y., Kobayashi, E., Okada, T., Hoshika, A., Ozawa, K., Kume, A.
    • Journal Title

      Gene Ther. 11

      Pages: 1081-1086

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.2004

    • Author(s)
      Ueda, K., Hanazono, Y., Shibata, H., Ageyama, N., Ueda, Y., Ogata, S., Tabata, T., Nagashima, T., Takatoku, M., Kume, A., Ikehara, S., Taniwaki, M., Terao, K., Hasegawa, M., Ozawa, K.
    • Journal Title

      Mol.Ther. 10

      Pages: 469-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Sustained transgene expression by human cord blood derived CD34(+) cells transduced with simian immunodeficiency virus agmTYO1-based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice.2004

    • Author(s)
      Kikuchi, J., Mimuro, J., Ogata, K., Tabata, T., Ueda, Y., Ishiwata, A., Kimura, K., Takano, K., Madoiwa, S., Mizukami, H., Hanazono, Y., Kume, A., Hasegawa, M., Ozawa, K., Sakata, Y.
    • Journal Title

      J Gene Med. 6

      Pages: 1049-1060

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice.2004

    • Author(s)
      Mochizuki S, Mizukami H, Ogura T, Kure S, Ichinohe A, Kojima K, Matsubara Y, Kobayashi E, Okada T, Hoshika A, Ozawa K, Kume A
    • Journal Title

      Gene Ther 11(13)

      Pages: 1081-1086

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] Adeno-associated virus vector-mediated interleukin-1O gene transfer inhibits atherosclerosis in apoprotein E-deficient mice.2004

    • Author(s)
      Yoshioka T, Okada T, Maeda Y, Ikeda U, Shimpo M, Nomoto T, Takeuchi K, Nonaska-Sarukawa M, Ito T, Takahashi T, Mizukami H, Hanazono Y, Kume A, Ookawara S, Kawano M, Ishibashi S, Shimada K, Ozawa K
    • Journal Title

      Gene Ther 11(24)

      Pages: 1772-1779

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene.2004

    • Author(s)
      Hara, T., Kume, A., Hanazono, Y., Mizukami, H., Okada, T., Tsurumi, H., Moriwaki, H., Ueda, Y., Hasegawa, M., Ozawa, K.
    • Journal Title

      Gene Ther. 11

      Pages: 1370-1377

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure : a scheme for the progression of cardiac dysfunction.2004

    • Author(s)
      Toyo-Oka, T., Kawada, T., Nakata, J., Xie, H., Urabe, M., Masui, F., Ebisawa, T., Tezuka, A., Iwasawa, K., Nakajima, T., Uehara, Y., Kumagai, H., Kostin, S., Schaper, J., Nakazawa, M., Ozawa, K.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 101

      Pages: 7381-7385

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.2004

    • Author(s)
      Kuribara, R., Honda, H., Matsui, H., Shinjyo, T., Inukai, T., Sugita, K., Nakazawa, S., Hirai, H., Ozawa.K., Inaba, T.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 6172-6183

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Method - Intra-bone marrow transplantation of hematopoietic stem cells in non-human primates : long-term engraftment without conditioning.2004

    • Author(s)
      Ueda, K., Hanazono, Y., Ageyama, N., Shibata, H., Ogata, S., Ueda, Y., Tabata, T., Ikehara, S., Taniwaki, M., Hasegawa, M., Terao, K., Ozawa, K.
    • Journal Title

      Gene Ther.Reg. 2

      Pages: 207-218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Adeno-associated virus (AAV) vector-mediated liver- and muscle-directed transgene expression using various kinds of promoters and serotypes.2004

    • Author(s)
      Mochizuki, S., Mizukami, H., Kume, A., Muramatsu, S., Takeuchi, K., Matsushita, T., Okada, T., Kobayashi, E., Hoshika, A., Ozawa K.
    • Journal Title

      Gene Ther.Mol.Biol. 8

      Pages: 9-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.2004

    • Author(s)
      Yoshioka, T., Okada, T., Maeda, Y., Ikeda, U., Shimpo, M., Nomoto, T., Takeuchi, K., Nonaka-Sarukawa, M., Ito, T., Takahashi, M., Matsushita, T., Mizukami, H., Hanazono, Y., Kume, A., Ookawara, S., Kawano, M., Ishibashi, S., Shimada, K., Ozawa, K.
    • Journal Title

      Gene Ther. 11

      Pages: 1772-1779

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] High-level in vivo gene marking after gene-modified autologous hematopoietic stem cell transplantation without marrow conditioning in nonhuman primates.2004

    • Author(s)
      Ueda K, Hanazono Y, Shibata H, Ageyama N, Ueda Y, Ogata S, Tabata T, Nagashima T, Takatoku M, Kume A, Ikehara S, Taniwaki M, Terao K, Hasegawa M, Ozawa K
    • Journal Title

      Mol Ther 10(3)

      Pages: 469-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390306
  • [Journal Article] In vivo expansion of gene-modified hematopoietic cells by a novel selective amplifier gene utilizing the erythropoietin receptor as a molecular switch.2004

    • Author(s)
      Nagashima, T., Ueda, Y., Hanazono, Y., Kume, A., Shibata, H., Ageyama, N., Terao, K., Ozawa, K., Hasegawa, M.
    • Journal Title

      J.Gene Med. 6

      Pages: 22-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Expression of human coagulation factor VIII in adipocytes transduced with the simian immunodeficiency virus agmTYO1-based vector for hemophilia A gene therapy.2004

    • Author(s)
      Ogata, K., Mimuro, J., Kikuchi, J., Tabata, T., Ueda, Y., Naito, M., Madoiwa, S., Takano, K., Hasegawa, M., Ozawa, K., Sakata, Y.
    • Journal Title

      Gene Ther. 11

      Pages: 253-259

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Separate control of Rep and Cap expression utilizing mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.2004

    • Author(s)
      Mizukami, H., Okada, T., Ogasawara, Y., Matsushita, T., Urabe, M., Kume, A., Ozawa, K.
    • Journal Title

      Mol.Biotechnol. 27

      Pages: 7-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-b peptide in mouse brain.2004

    • Author(s)
      Iwata, N., Mizukami, H., Shirotani, K., Takaki, Y., Muramatsu, S., Lu, B., Gerard, N.P., Gerard, C., Ozawa, K.Saido, T.C.
    • Journal Title

      J.Neurosci. 24

      Pages: 991-998

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.2004

    • Author(s)
      Okada, T., Caplen, N.J., Ramsey, W.J., Onodera, M., Shimazaki, K., Nomoto, T., Ajalli, R., Wildner, O., Morris, J., Kume, A., Hamada, H., Blaese, R.M., Ozawa, K.
    • Journal Title

      J.Gene Med. 6

      Pages: 288-289

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.

    • Author(s)
      Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., Urabe, M., Kume, A., Hamada, H., Yoshikawa, H., Sakata, Y., Ozawa, K.
    • Journal Title

      J.Gene Med. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390281
  • [Patent] ベクター産生型腫瘍標的細胞2007

    • Inventor(s)
      岡田尚巳, 小澤敬也
    • Industrial Property Rights Holder
      自治医大
    • Industrial Property Number
      2006-116504
    • Filing Date
      2007-01-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390418
  • [Patent] 遺伝子導入効率増強剤2005

    • Inventor(s)
      岡田尚巳, 小澤敬也
    • Industrial Property Rights Holder
      日本ウェイトマネージメント, 岡田尚巳
    • Filing Date
      2005-10-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390418
  • [Patent] 遺伝子導入効率増強剤2005

    • Inventor(s)
      岡田 尚巳, 小澤 敬也
    • Industrial Property Rights Holder
      日本ウェイトマネージメント, 岡田 尚巳
    • Filing Date
      2005-10-24
    • Data Source
      KAKENHI-PROJECT-16390418
  • [Patent] ウイルス中空粒子の迅速除去および精製方法2005

    • Inventor(s)
      岡田 尚巳, 小澤 敬也
    • Industrial Property Rights Holder
      Pall Life Science
    • Industrial Property Number
      2005-314476
    • Filing Date
      2005-10-28
    • Data Source
      KAKENHI-PROJECT-16390418
  • [Patent] ウイルス中空粒子の迅速除去および精製方法2005

    • Inventor(s)
      岡田尚巳, 小澤敬也
    • Industrial Property Rights Holder
      Pall Life Science
    • Industrial Property Number
      2005-314476
    • Filing Date
      2005-10-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390418
  • [Presentation] The NFAT response elements in the IL-2 gene promoter permit visualization and quantification of activation status in CAR-expressing PBMCs.2014

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
    • Organizer
      第20回日本遺伝子治療学会
    • Place of Presentation
      東京
    • Year and Date
      2014-08-08
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Activation signals from CAR permit NFAT-controlled inducible expression of transgenes in PBMCs.2014

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-02
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Tol2 transposon-based gene transfer of CD19-specific chimeric antigen receptors into human T-cells.2014

    • Author(s)
      Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Teruya T, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R, Kawakami K and Ozawa K.
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-02
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Activation signals from chimeric antigen receptors permit NFAT-controlled inducible expression of transgene in PBMCs.2014

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Analysis of function and response specificity of a switch promoter driven by activation signals from a CD19-targeted chimeric antigen receptor.2014

    • Author(s)
      Uchibori R, Takeshi T, Tsukahara T, Ohmine K, Riviere I, Brentjens RJ, Sadelain M, Mineno J, Takesako K, Ozawa K.
    • Organizer
      The 5th Meeting of Asian Cellular Therapy Organization.
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] フィラデルフィア染色体陽性急性白血病に対するPSL併用Dasatinib療法の効果と安全性に関する報告2014

    • Author(s)
      翁 家国, 多々良 礼音, 藤原 慎一郎, 大嶺 謙, 鈴木 隆浩, 永井 正, 室井 一男, 小澤 敬也
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] B細胞リンパ腫に合併した腫瘍随伴性天疱瘡と考えた1例2014

    • Author(s)
      坂口 優, 宮本 有希子, 佐藤 篤子, 藤田 有理香, 小宮根 真弓, 村田 哲, 大槻 マミ太郎, 佐藤 一也, 大嶺 謙, 小澤 敬也
    • Organizer
      第113回 日本皮膚科学会総会
    • Place of Presentation
      京都
    • Year and Date
      2014-05-30
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Generation of T-cells expressing a CD19-specific CAR by the Tol2 transposon system.2014

    • Author(s)
      Tsukahara T, Ohmine K, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Development of switch promoters that is activated to induce exogenous gene expression upon the recognition of CD19 by chimeric antigen receptors.2014

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
    • Organizer
      17th Annual Meeting of the American Society of Gene & Cell Therapy.
    • Place of Presentation
      Washington, D.C.
    • Year and Date
      2014-05-22
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Tol2 transposon-mediated gene transfer of CD19-CAR to primary human T-cells for the treatment of B-cell malignancies.2014

    • Author(s)
      Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Takeshi T, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R J, Kawakami K, Ozawa K.
    • Organizer
      第20回日本遺伝子治療学会
    • Place of Presentation
      東京
    • Year and Date
      2014-08-08
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] キメラ抗原受容体からの抗原刺激特異的な遺伝子発現誘導系の開発.2014

    • Author(s)
      内堀 亮介, 二宮 空暢, 照屋 武志, 塚原 智典, 大嶺 謙, 峰野 純一, 竹迫 一任, 小澤 敬也.
    • Organizer
      第6回血液疾患免疫療法研究会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-06
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Molecular Mechanisms of Immunosuppressive Activity of MSCs(Mesenchymal Stem Cells)2008

    • Author(s)
      Ozawa, K.
    • Organizer
      第30回日本造血細胞移植学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-29
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Presentation] 骨髄間葉系幹細胞を用いた細胞治療/遺伝子治療の開発2008

    • Author(s)
      小澤 敬也
    • Organizer
      第7回日本再生医療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-03-14
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Presentation] AAV Vectors for Gene Therapy of Parkinson's Disease2008

    • Author(s)
      Ozawa, K
    • Organizer
      The 11^<th> Annual Meeting of American Society of Gene Therapy
    • Place of Presentation
      Boston
    • Year and Date
      2008-05-28
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Presentation] Molecular Mechanisms of Immunosuppressive Activity of MSCs (Mesenchymal Stem Cells)2008

    • Author(s)
      Ozawa, K.
    • Organizer
      第30回日本造血細胞移植学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-29
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Presentation] MSC (mesenchymal stem cell)-based cell and gene therapy.2007

    • Author(s)
      Ozawa, K. et al.
    • Organizer
      13th ISCT (International Society for Cellular Therapy) Annual Meeting
    • Place of Presentation
      Sydney
    • Year and Date
      2007-06-26
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Presentation] Application of AAV(Adeno-Associated virus)to gene therapy2007

    • Author(s)
      Ozawa, K.
    • Organizer
      The 13th Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-06-28
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Presentation] MSC(mesenchymal stem cell)-based cell and gene therapy2007

    • Author(s)
      Ozawa, K.
    • Organizer
      13^<th> ISCT(lnternational Society for Cellular Therapy)Annual Meeting
    • Place of Presentation
      Sydney
    • Year and Date
      2007-06-26
    • Data Source
      KAKENHI-PROJECT-19390267
  • [Presentation] 遺伝子治療の方法と可能性2007

    • Author(s)
      小澤 敬也
    • Organizer
      日本病院薬剤師会関東ブロック第37回学術大会
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-08-26
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Presentation] AAV(Adeno-Associated virus)ベクターを用いた神経系疾患の遺伝子治療2007

    • Author(s)
      Ozawa, K.
    • Organizer
      第23回日本DDS学会学術集会
    • Place of Presentation
      熊本
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-17016067
  • [Presentation] Development of switch promoters driven by activation signals from the chimeric antigen receptors.

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Anti-tumor activity of CD19-specific chimeric antigen receptor-modified T-cells for B cell lymphoma.

    • Author(s)
      Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Tumor targeting using T-lymphocytes with an anti-CD19 chimeric antigen receptor for B cell lymphoma.

    • Author(s)
      Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] DEVELOPMENT OF SIN RETROVIRAL VECTORS EQUIPPED WITH SWITCH PROMOTERS DRIVEN BY ACTIVATION SIGNALS FROM THE CHIMERIC ANTIGEN RECEPTORS.

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
    • Organizer
      第18回日本遺伝子治療学会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Development of switch promoters that would respond to activation signals from the chimeric antigen receptors.

    • Author(s)
      Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-24390247
  • [Presentation] Tumor targeting and anti-tumor activity mediated by T-lymphocytes with an anti-CD19 CAR in human B-cell lymphoma models.

    • Author(s)
      Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
    • Organizer
      第18回日本遺伝子治療学会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24390247
  • []

  • 1.  ASANO Shigetaka (50134614)
    # of Collaborated Projects: 19 results
    # of Collaborated Products: 0 results
  • 2.  URABE Masashi (40213516)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 14 results
  • 3.  KUME Akihiro (10264293)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 26 results
  • 4.  TANI Kenzaboro (00183864)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 5.  TOJO Arinobo (00211681)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  MANO Hiroyuki (90240704)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 2 results
  • 7.  MIZUKAMI Horoaki (20311938)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 37 results
  • 8.  SAKAI Ryuichi (40215603)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 9.  OKADA Takashi (00326828)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 17 results
  • 10.  HONDA Hiroaki (40245064)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  SUDA Toshio (60118453)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  MATSUSHITA Takashi (20343444)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 13.  SATO Noriharu (90162461)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  OHWADA Michitaka (40203955)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  SUZUKI Mitsuaki (50110870)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  新津 洋司郎 (10045502)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  斉藤 英彦 (20153819)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  小林 幸夫 (50240734)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  HASEGAWA Mamoru
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  TSUKAHARA Tomonri (10362120)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 21.  UCHIBORI Ryosuke (20458285)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 22.  KOBAYASHI Hiroshi (40178330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  HANAZONO Yutaka (70251246)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  小倉 浩美 (90211135)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  中畑 龍俊 (20110744)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  帯刀 益夫 (10099971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  小川 一誠 (70124245)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  渡部 好彦 (90109075)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  内山 卓 (80151900)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  岡本 真一郎 (50160718)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  太田 茂 (60160503)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 32.  水野 美邦 (30049043)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 33.  斎藤 泉 (70158913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 34.  OZAKI Katsutoshi (10286453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 35.  OHMINE Ken (90316521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 36.  IKEBUCHI Kenji (20175194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  TAKAHASHI Satoshi (60226834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  MORISHITA Kazuhiro (80260321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  MIYAJIMA Atsushi (50135232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  NAKANO Toru (00172370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  KITAMURA Yukihiko (70028520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  NISHIKAWA Sinichi (60127115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  KAWAI Kosei (20305452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  XIN Ke-qin (40301452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  SAITO Tomoyuki (30170517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  TOYO-OKA Teruhiko (00146151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  KURACHI Kotoku (70344223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  TOBKUNAGA Katsushi (40163977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  UEHARA Yoshio (40184965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  YAMASHITA Yoshihiro (10326861)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 51.  SAGA Yasushi (70360071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  勝木 元也 (20051732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  八木田 秀雄 (30182306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  木村 淳 (10204976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  太田 成男 (00125832)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  永津 俊治 (40064802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  桐野 高明 (10161605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  吉田 充男 (70048966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  小林 一三 (30126057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  直井 信 (50022786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  清水 信義 (50162706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  小川 紀雄 (90033208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  柳原 武彦 (70243201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  永津 郁子 (80084573)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  金田 安史 (10177537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  島田 隆 (20125074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  吉田 輝彦 (10191602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  杉本 芳一 (10179161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  吉田 進昭 (10250341)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 70.  北村 俊雄 (20282527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 71.  竹田 潤二 (50163407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 72.  生田 宏一 (90193177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  宮里 彰 (10306152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  鐘ヶ江 裕美 (80251453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  多比良 和誠 (10261778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  伊庭 英夫 (60111449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 77.  河合 孝誠 (00264656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 78.  幸道 秀樹 (80161876)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 79.  白藤 尚毅 (00206301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 80.  山本 雅 (40134621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 81.  渋谷 正史 (10107427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 82.  SAKATA Tsuneaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 83.  TAKAHASHI Tohru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 84.  MADOIWA Seiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 85.  OHMORI Tsukasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 86.  TATARA Raine
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 87.  HARADA Yuka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 88.  一瀬 宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 89.  室井 一男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 90.  渡辺 大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 91.  三室 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 92.  原田 浩徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 93.  川上 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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