ARIMURA Kimiyoshi 有村公良

Researcher Number	30140908
Affiliation (based on the past Project Information) *help	2011: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2009: 鹿児島大学, 医歯学総合研究科, 准教授 2008 – 2009: 鹿児島大学, 大学院・医歯学総合研究科, 准教授
Review Section/Research Field	Except Principal Investigator Neurology
Keywords	Except Principal Investigator SSBR / Tdp1 / 一本鎖DNA修復 / ノックアウトマウス / SCAN1 / 遺伝子治療 / 末梢神経障害 / Desert hedgehog / 一本鎖DNA修 / DNA repair … More / コラーゲンVI / 皮膚線維芽細胞 / Ullrich型先天性筋ジストロティー / collagen VI / ベスレムミオパチー / ウルリッヒ病 / 細胞接着 / 実験的治療 / thrombomodulin / 関節拘縮 / Bethlemミオパチー / Ullrich病 / 6型コラーゲン / 遺伝性末梢神経障害 / マウスモデル / TDP1 / 神経変性 / DNA修復 / ニューロパチー / 脊髄小脳変性症 / 再生医療 / 末梢神経 / desert hedgehog / 遺伝子変異 / シュワン細胞 Less

Desert hedgehog遺伝子変異による神経障害の病態解明と治療法の開発
- Principal Investigator
  
  梅原藤雄
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Study on the development of treatments for collagen VI related myopathy.
- Principal Investigator
  
  HIGUCHI Itsuro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Pathomechanism of spinocereballar ataxia with axonal neuropathy(SCAN1)-DNA single strand break repair and neurodegeneration
- Principal Investigator
  
  TAKASHIMA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Investigation for the pathogenesis of neurological disorders due to Desert hedgehog gene mutation and development of new treatment
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Pathogenesis of SCAN1, analysis of Tdp1 knockout mice
- Principal Investigator
  
  HIROSHI Takashima
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University

All 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] Annual Review 神経 2007 常染色体性劣性遺伝形式の末梢神経障害および小脳失調症を示す疾患2007
- Author(s)
  高嶋博, 有村公良
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy2011
- Author(s)
  Sakiyama Y, Okamoto Y, Higuchi I, Inamori Y, Sangatsuda Y, Michizono K, Watanabe O, Hatakeyama H, Goto YI, Arimura K, Takashima H.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 121(6) Pages: 775-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591095
[Journal Article] A new mitochondria-related disease showing myopathy with episodic hyper-CKemia2011
- Author(s)
  Okamoto Y, Higuchi I, Sakiyama Y, Tokunaga S, Watanabe O, Arimura K, Nakagawa M, Takashima H.
- Journal Title
  
  Ann Neurol
  
  Volume: 70(3) Pages: 486-492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591095
[Journal Article] A new mitochondria-related disease showing myopathy with episodic hyper-creatine kinase-emia2011
- Author(s)
  Okamoto Y, Higuchi I, Sakiyama Y, Tokunaga S, Watanabe O, Arimura K, Nakagawa M, Takashima H.
- Journal Title
  
  Ann Neurol
  
  Volume: 70(3) Pages: 486-492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591094
[Journal Article] A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy2011
- Author(s)
  Sakiyama Y, Okamoto Y, Higuchi I, Inamori Y, Sangatsuda Y, Michizono K, Watanabe O, Hatakeyama H, Goto Y, Arimura K, Takashima H.
- Journal Title
  
  Acta Neuropathol
  
  Volume: 121(6) Pages: 775-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591094
[Journal Article] Clinical and Genetic Characterization of 16q-Linked Autosomal Dominant Spinocerebellar Ataxia in South Kyushu, Japan2009
- Author(s)
  Hirano R, Takashima H, Okubo R, Okamoto R, Maki Y, Ishida S, Suehara M, Hokezu Y, Arimura K.
- Journal Title
  
  J Hum Genet (in press ePub)
  
  Pages: 0-0
- NAID
  10030730887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009
- Author(s)
  Araya N, Arimura H, Kawahara K, Yagishita N, Ishida J, Fujii R, Aratani S, Fujita H, Sato T, Yamano Y, Higuchi I, Osame M, Nishioka K, Fukamizu A, Arimura K, Maruyama I, Nakajima T.
- Journal Title
  
  Int J Mol Med
  
  Volume: 24 Pages: 605-611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591094
[Journal Article] Clinical and genetic characterization of 16q-linked autosomal dominant spinocerebellar ataxia in South Kyushu, Japan2009
- Author(s)
  Hirano R, Takashima H, Okubo R, Hokezu Y, Arimura K, et al
- Journal Title
  
  J Hum Genet
  
  Volume: 54(7) Pages: 377-81
- NAID
  10030730887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591095
[Journal Article] Clinical and genetic characterization of 16q-linked autosomal dominants pinocerebellar ataxia in South Kyushu, Japan2009
- Author(s)
  Hirano R, Takashima H, Okubo R, Hokezu Y, Arimura K.
- Journal Title
  
  Journal of Human Genetics 54
  
  Pages: 377-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591095
[Journal Article] Diagnostic value of serum peptidome analyses for protease activated pathological conditions beyond cancer diagnosis2009
- Author(s)
  Hashiguchi T, Tanaka K, Lee LJ, Sasaki K, Natsugoe S, Kawahara K, Arimura K, Maruyama I.
- Journal Title
  
  Medical Hypotheses 73
  
  Pages: 760-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591095
[Journal Article] Enlarged multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia2008
- Author(s)
  Umehara, F. Hagiwara, T. Yoshimura, M. Higashi, K. Arimura, K.
- Journal Title
  
  J Neurol Sci 266
  
  Pages: 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Genetically confirmed patients with Merosin-deficient congenital Muscular dystrophy in China2008
- Author(s)
  Yuan J, Takashima H, Higuchi I, Arimura K, Li N, Zhao Z, Shen H, Hu J.
- Journal Title
  
  Neuropediatrics 39
  
  Pages: 264-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan.2008
- Author(s)
  Matsuura E, Umehara F*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Enlarged, multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia.2008
- Author(s)
  Umehara F, Hagiwara T, Yoshimura M, Higashi K, Arimura K
- Journal Title
  
  J Neurol Sci 266
  
  Pages: 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Enlarged, multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia.2008
- Author(s)
  Umehara, F^*. Hagiwara, T. Yoshimura, M. Higashi, K. Arimura, K.
- Journal Title
  
  J Neurol Sci 266
  
  Pages: 167-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection: eleven patients from an endemic area in Japan2008
- Author(s)
  Matsuura E, Umehara F*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Inclusion body myositis associated with human T-lymphotropic virus-type I infection : eleven patients from an endemic area in Japan.2008
- Author(s)
  Matsuura E, Umehara F^*, Nose H, Higuchi I, Matsuoka E, Izumi K, Kubota R, Saito M, Izumo S, Arimura K, Osame M.
- Journal Title
  
  J Neuropathol Exp Neurol 67
  
  Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] POEMS 症候群(Crow-Fukase 症候群)2008
- Author(s)
  梅原藤雄、有村公良
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 244-245
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy2008
- Author(s)
  Hayashi D, Kubota R, Takenouchi N, Nakamura T, Umehara F, Arimura K, Izumo S, Osame M.
- Journal Title
  
  J Neurovirol 14
  
  Pages: 459-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] 遺伝性ニューロパチーの進歩2007
- Author(s)
  高嶋博, 有村公良
- Journal Title
  
  Clinical Neuroscience 25(7)
  
  Pages: 752-754
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] Abnormalities of spinal magnetic resonance images implicate clinical variability in human T-cell lymphotropic virus type I-associated myelopathy.2007
- Author(s)
  Umehara F, Nose H, Saito M, Fukuda M, Ogino M, Toyota T, Yuhi T, Arimura K, Osame M.
- Journal Title
  
  J Neurovirol 13
  
  Pages: 260-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Spinocerebellar ataxia with axonal neuropathy : consequence of a Tdp1 recessive neomorphic mutation2007
- Author(s)
  Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF
- Journal Title
  
  EMBO J. 26
  
  Pages: 4732-4743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Abnormalities of spinal magnetic resonance images implicate clinical variability in human T-cell lymphotropic virus type I-associated myelopathy2007
- Author(s)
  Umehara F, Nose H, Saito M, Fukuda M, Ogino M, Toyota T, Yuhi T, Arimura K, Osame M.
- Journal Title
  
  J Neurovirol 13
  
  Pages: 260-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] 末梢神経障害の治療の進歩2007
- Author(s)
  梅原藤雄、有村公良
- Journal Title
  
  神経治療学 24
  
  Pages: 445-448
- Data Source
  KAKENHI-PROJECT-19591000
[Journal Article] Spinocerebellar ataxia with axonal neuropathy : consequence of a Tdp1 recessive neomorphic mutation?2007
- Author(s)
  Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, Takashima H, Boerkoel CF
- Journal Title
  
  EMBO J. 26(22)
  
  Pages: 4732-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591001
[Journal Article] 遺伝性ニューロパチーの進歩2007
- Author(s)
  高嶋博, 有村公良
- Journal Title
  
  Clinical Neuroscience 25
  
  Pages: 752-754
- Data Source
  KAKENHI-PROJECT-19591001
[Presentation] MFN2点変異を有する軸策型Charcot-Marie-Tooth病17例の検討2011
- Author(s)
  橋口昭大、中村友紀、徳永章子、岡本裕嗣、高嶋博、有村公良
- Organizer
  第22回日本末梢神経学会学術集会
- Place of Presentation
  宜野湾
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21591095
[Presentation] MFN2点変異を有する軸策型Charcot-Marie-Tooth病13例の検討2011
- Author(s)
  橋口昭大、中村友紀、徳永章子、岡本裕嗣、高嶋博、有村公良
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21591095
[Presentation] Immunohistochemical studies on HSP47 and vessel related proteins in inclusion body myositis and muscular dystrophies2010
- Author(s)
  Itsuro Higuchi, Yukie Inamori, Keiko Higashi, Eiji Matsuura, Akihiro Hashiguchi, Tadafumi Shiraishi, Noriko Hirata, Kimiyoshi Arimura
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21591094
[Presentation] マイクロアレイDNAチップによるCharcot-Marie-Tooth病の遺伝子診断2010
- Author(s)
  徳永章子、橋口昭大、岡本裕嗣、中村友紀、有村公良、高嶋博
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21591095
[Presentation] Immunohistochemical studies on HSP47 and vessel related proteins in inclusion body myositis and muscular dystrophies.2010
- Author(s)
  Itsuro Higuchi, Yukie Inamori, Keiko Higashi, Eiji Matsuura, Akihiro Hashiguchi, Tadafumi Shiraishi, Noriko Hirata, Kimiyoshi Arimura
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples, Italy
- Data Source
  KAKENHI-PROJECT-21591094
[Presentation] Desert hedgehog遺伝子移入による末梢神経障害治療法の開発2007
- Author(s)
  梅原藤雄、白濱ゆう子、有村公良川原幸一、橋口照人、丸山征郎楯玄秀
- Organizer
  平成19年度厚生労働省難治性ニューロパチーの病態に基づく新規治療法の開発研究班会議
- Place of Presentation
  東京
- Year and Date
  2007-12-06
- Data Source
  KAKENHI-PROJECT-19591000

1. HIROSHI Takashima (80372803)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. UMEHARA Fujio (20271140)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. HASHIGUCHI Teruto (70250917)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. ARIMURA Kimiyoshi (20159510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HIRANO Ryuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. NAKAMURA Tomonori

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. HASHIGUCHI Akihiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. HIGUCHI Itsuro (80183573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. OKAMOTO Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. BOERKOEL Cornelius F.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

ARIMURA Kimiyoshi 有村 公良

Research Projects

Research Products

Co-Researchers

Desert hedgehog遺伝子変異による神経障害の病態解明と治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the development of treatments for collagen VI related myopathy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathomechanism of spinocereballar ataxia with axonal neuropathy(SCAN1)-DNA single strand break repair and neurodegeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for the pathogenesis of neurological disorders due to Desert hedgehog gene mutation and development of new treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of SCAN1, analysis of Tdp1 knockout mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Annual Review 神経 2007 常染色体性劣性遺伝形式の末梢神経障害および小脳失調症を示す疾患2007

Author(s)

Publisher

Data Source

[Journal Article] A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy2011

Author(s)

Journal Title

Data Source

[Journal Article] A new mitochondria-related disease showing myopathy with episodic hyper-CKemia2011

Author(s)

Journal Title

Data Source

[Journal Article] A new mitochondria-related disease showing myopathy with episodic hyper-creatine kinase-emia2011

Author(s)

Journal Title

Data Source

[Journal Article] A new phenotype of mitochondrial disease characterized by familial late-onset predominant axial myopathy and encephalopathy2011

Author(s)

Journal Title

Data Source

[Journal Article] Clinical and Genetic Characterization of 16q-Linked Autosomal Dominant Spinocerebellar Ataxia in South Kyushu, Japan2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009

Author(s)

Journal Title

Data Source

[Journal Article] Clinical and genetic characterization of 16q-linked autosomal dominant spinocerebellar ataxia in South Kyushu, Japan2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Clinical and genetic characterization of 16q-linked autosomal dominants pinocerebellar ataxia in South Kyushu, Japan2009

Author(s)

Journal Title

Data Source

[Journal Article] Diagnostic value of serum peptidome analyses for protease activated pathological conditions beyond cancer diagnosis2009

Author(s)

Journal Title

Data Source

[Journal Article] Enlarged multifocal upper limb neuropathy with HTLV-I associated myelopathy in a patient with chronic adult T-cell leukemia2008

Author(s)

Journal Title

Data Source

ARIMURA Kimiyoshi 有村公良