shibukawa akimasa 澁川明正

… Alternative Names

SHIBUKAWA Akimasa 澁川明正

渋川明正シブカワアキマサ

澁川明正シブカワアキマサ

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Researcher Number	30170913
Other IDs
Affiliation (Current)	2025: 千葉科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2004: Chiba Institute of Science, Faculty of Pharmaceutical Sciences, 薬学部, 教授 2003: 京都大学, 薬学研究科, 助教授 1997 – 2001: 京都大学, 薬学研究科, 助教授 1999: 京都大学, 大学院・薬学研究科, 助教授 1993 – 1995: 京都大学, 薬学部, 助手 1990: 京都大学, 薬学部, 助手 1986 – 1988: 京都大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical pharmacy Except Principal Investigator Physical pharmacy
Keywords	Principal Investigator キャピラリー電気泳動 / 先端分析 / タンパク結合 / HPLC / LDL / capillary electrophoresis / アルブミン / thyroxine / albumin / protein binding … More / チロキシン / チロキシ / liposome / flvastatin / nilvadipine / frontal analysis / binding analysis / lipoprotein / 低密度リポタンパク質 / 血漿リポタンパク質 / リポタンパク / リポソーム / フルバスタチン / ニルバジピン / 結合分析 / リポタンパク質 / isoelectric focusing / alpha_1-acid glycoprotein / キャピタリー電気泳動 / α_<1->酸性糖タンパク / 等電点電気泳動 / キャピアリー電気泳動 / α_1-酸性糖タンパク / 酵素反応 / o-ニトロフェニル-β-ガラクトシド / β-ガラクトシダーゼ / 高速液体クロマトグラフィー / alpha1-酸性糖タンパク … More Except Principal Investigator apo A-1 / セレノトリスルフィド / セレン / Membrane receptor / Growth hormone receptor / Growth hormone / Size exclusion chromatography / Affinity chromatography / Purification / Membrane protein / 受容体の高速分離精製 / 膜タンパク質の分離精製 / 膜タンパク質 / 架橋剤 / 固定化タンパク質 / グルタルアルデヒドポリマー / グルタルアルデヒド / 膜タンパク質の迅速精製システム / グルタルアルデヒドオリゴマー / 膜受容体 / 成長ホルモン受容体 / 成長ホルモン / サイズ排除クロマトグラフィー / アフィニティークロマトグラフィー / 精製 / 膜タンパク / HPLC / Determination Method / Metabolism / Model Reaction / Selenotrisulfide / Biologically Relevant Thiol / Selenium / 環境試料 / 螢光分析 / NBDF / チオール / ペニシラミンセレノトリスルフィド / 必須元素 / 蛍光検出 / 高速液体クロマトグラフィー / 定量法 / 代謝 / モデル反応 / 生体関連チオール / Monte Carlo-cal / any loid / low density lipo-protein / high performance fromtall Analysis / Highly fine structure / Biosuper molecular Assembly / SPR / シミュレーション / アルツハイマー / レセプター / 血漿アポリポタンパク質 / 脂質2分子層 / 低密度血漿リポタンパク質 / 表面プラスモン共鳴 / apoA-1 / 表面ブラズモン共鳴 / モンテカルロ計算 / アミロイド / 低密度リポタンパク質 / 高性能先端分析法 / 高次微細構造 / 生体超分子集合体 / 表面プラズモン共鳴 / capillary electrophoresis / prion protein / sodium channel inactivation gate peptide / ESI-T0F-MS / high-performance frontal analysis / microheterogeneity / plasma protein binding / glycochain / プリオン蛋白 / Naチャンネル蛋白 / 電子スプレー型飛行時間質量分析 / 高速先端分析法 / 糖鎖ミクロ不均一性 / 薬物・タンパク結合解析 / 糖タンパク質糖鎖 / チオール交換反応 / 混合チオールセレノトリスルフィド / カプトプリル / 潅流速度 / 非平衡拡散モデル / 腸肝循環 / MULTI(FILT) / cefixime / 肝局所動態 / 高速ラプラス逆変換 Less

Bioanalytical study of the effect of protein variants upon biological activity of endogenous compoundsPrincipal Investigator
- Principal Investigator
  
  SHIBUKAWA Akimasa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba Institute of Science
  Kyoto University
医薬品化学領域における生体超分子集合体の高次微細構造と機能に関する研究
- Principal Investigator
  
  TAGA Tooru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Development of fine micro analytical method of drug recognition function of sugar chains
- Principal Investigator
  
  NAKAGAWA Terumichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Change of drug binding ability of plasma lipoproteins due to oxidative modificationPrincipal Investigator
- Principal Investigator
  
  SHIBUKAWA Akimasa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Development of novel system to analyze microheterogeneity of alpha_1-acid glycoproteinPrincipal Investigator
- Principal Investigator
  
  SHIBUKAWA Akimasa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
超微量酵素反応解析法の開発Principal Investigator
- Principal Investigator
  
  澁川明正
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
強タンパク親和性薬物の定量的結合解析法の開発とその応用Principal Investigator
- Principal Investigator
  
  澁川明正
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
キャピラリー電気泳動による生理活性物質と生体成分との相互作用評価法の開発Principal Investigator
- Principal Investigator
  
  渋川明正
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
拡散モデルによる薬物の肝潅流実験デ-タ解析[高速逆ラプラス変換の応用]
- Principal Investigator
  
  山岡清
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
チオール基を有する医薬品と生体内微量元素としてのセレンとの相互作用
- Principal Investigator
  
  TANAKA Hisashi
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of High-Performance Liquid Chromatographic System for the Rapid Purification of Membrane Receptors
- Principal Investigator
  
  NAKAGAWA Terumichi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Analysis of Reaction with Biologically Relevant Thiols as a Model Reaction for Metabolism of Selenium
- Principal Investigator
  
  TANAKA Hisashi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University

All 2005 Other

All Journal Article

[Journal Article] Simultaneous determination of unbound thyroid hormones in human plasma2005
- Author(s)
  T.Kimura, K.Nakanishi, T.Nakagawa, A.Shibukawa, K.Matsuzaki
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis 38
  
  Pages: 204-209
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590041
[Journal Article] High-performance frontal analysis of the binding of thyroxine enantiomers to human serum albumin2005
- Author(s)
  Tomoko Kimura, Keiko Nakanishi, Terumichi Nakagawa, Akimasa Shibukawa, Katsumi Matsuzaki
- Journal Title
  
  Pharmaceutical Research 22
  
  Pages: 667-675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590041
[Journal Article] High-performance frontal analysis of the binding of thyroxine enantiomers to human serum albumin2005
- Author(s)
  T.Kimura, K.Nakanishi, T.Nakagawa, A.Shibukawa, K.Matsuzaki
- Journal Title
  
  Pharmaceutical Research 22
  
  Pages: 667-675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590041
[Journal Article] Simultaneous determination of unbound thyroid hormones in human plasma using high performance frontal analysis with electrochemical detection2005
- Author(s)
  Tomoko Kimura, Keiko Nakanishi, Terumichi Nakagawa, Akimasa Shibukawa, Katsumi Matsuzaki
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis 38
  
  Pages: 204-209
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590041
[Journal Article] Simultaneous determination of unbound thyroid hormones in human plasma
- Author(s)
  T.Kimura, K.Nakanishi, T.Nakagawa, A.Shibukawa, K.Matsuzaki
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis (in press)
- Data Source
  KAKENHI-PROJECT-15590041
[Journal Article] High-performance frontal analysis of the binding of thyroxine enantiomers to human serum albumin
- Author(s)
  T.Kimura, K.Nakanishi, T.Nakagawa, A.Shibukawa, K.Matsuzaki
- Journal Title
  
  Pharmaceutical Research (in press)
- Data Source
  KAKENHI-PROJECT-15590041

1. NAKAGAWA Terumichi (70025708)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. TANAKA Hisashi (50025673)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KURODA Yoshihiro (90093236)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 山岡清 (50109013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KURODA Yukihiro (60314225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAGA Tooru (00025694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HONDA Tetsuro (00025719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUMOTO Osamu (10231599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. CHIKUMA Masahiko (50025699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

shibukawa akimasa 澁川 明正

SHIBUKAWA Akimasa 澁川 明正

渋川 明正 シブカワ アキマサ

澁川 明正 シブカワ アキマサ

Research Projects

Research Products

Co-Researchers

Bioanalytical study of the effect of protein variants upon biological activity of endogenous compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

医薬品化学領域における生体超分子集合体の高次微細構造と機能に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of fine micro analytical method of drug recognition function of sugar chains

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Change of drug binding ability of plasma lipoproteins due to oxidative modificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel system to analyze microheterogeneity of alpha_1-acid glycoproteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

超微量酵素反応解析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

強タンパク親和性薬物の定量的結合解析法の開発とその応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

キャピラリー電気泳動による生理活性物質と生体成分との相互作用評価法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

拡散モデルによる薬物の肝潅流実験デ-タ解析[高速逆ラプラス変換の応用]

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

チオール基を有する医薬品と生体内微量元素としてのセレンとの相互作用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of High-Performance Liquid Chromatographic System for the Rapid Purification of Membrane Receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Reaction with Biologically Relevant Thiols as a Model Reaction for Metabolism of Selenium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Simultaneous determination of unbound thyroid hormones in human plasma2005

shibukawa akimasa 澁川明正

SHIBUKAWA Akimasa 澁川明正

渋川明正シブカワアキマサ

澁川明正シブカワアキマサ