Takakura Yoshinobu 高倉喜信

… Alternative Names

TAKAKURA Yoshinobu 高倉喜信

高倉善信タカクラヨシノブ

高倉喜信

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Researcher Number	30171432
Other IDs
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Affiliation (Current)	2025: 京都大学, 薬学研究科, 特任教授 2025: 京都大学, 白眉センター, 特定職員
Affiliation (based on the past Project Information) *help	2023: 京都大学, 薬学研究科, 特任教授 2016 – 2022: 京都大学, 薬学研究科, 教授 2011 – 2016: 京都大学, 薬学研究科(研究院), 教授 2015: 京都大学, 大学院薬学研究科, 教授 2014: 京都大学, 薬学研究科, 教授 … More 2013: 京都大学, 大学院薬学研究科, 教授 2011 – 2013: 京都大学, 大学院・薬学研究科, 教授 1997 – 2012: Kyoto University Graduate Sch.Pharm.Sci.Professor, 薬学研究科, 教授 1999: 京都大学, 大学院・薬学研究科, 教授 1993 – 1996: 京都大学, 薬学部, 助教授 1991: Kyoto University, Faculty of Pharmaceutical Sciences, Instructor, 薬学部, 助手 1988 – 1989: 京都大学, 薬学部, 助手 1986: 京都大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Medical pharmacy / 応用薬理学・医療系薬学 / Biological Sciences / Biological pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 90:Biomedical engineering and related fields Except Principal Investigator Applied pharmacology / Physical pharmacy / Physical pharmacy … More / 応用薬理学・医療系薬学 / Basic Section 90120:Biomaterials-related / Biological pharmacy / 医薬分子機能学 Less
Keywords	Principal Investigator プラスミドDNA / 遺伝子治療 / DNAワクチン / 抗原提示細胞 / サイトカイン / CpGモチーフ / 樹状細胞 / インターフェロン / ドラッグデリバリー / RNA干渉 … More / 肝臓 / 局所投与 / plasmid DNA / DNA vaccination / Intracellular trafficking / デリバリー / 細胞内動態 / エクソソーム / 細胞外小胞 / Hsp70 / Cytotoxic T cell / Delivery / Plasmid DNA / Dendritic cell / 細胞障害性T細胞 / 抗体産生 / local administration / CpG motif / macrophage / gene therapy / 細胞取り込み / マクロファージ / poly (L-lysine) / 抗原特異的免疫応答 / 物理刺激 / 転写因子 / 遺伝子発現 / 融合タンパク質 / 熱ショックタンパク質 / ルシフェラーゼ / siRNA発現ベクター / 遺伝子ノックダウン / ハイドロダイナミクス法 / 体内動態 / アンチセンスDNA / デリバリーシステム / 内因性 / 免疫 / 免疫療法 / エキソソーム / エレクトロポレーション / MHC class I / プラスミド / Intradermal injection / Electroporation / 免疫応答 / DNAキャリアー / 皮内投与 / エレクトロポーレション / antibody production / cationic carrier / dendritic cell / DNA vaccine / カチオン性高分子 / カチオン性キャリアー / antisense oligonucleotide / drug delivery system / solid tumors / 単離腫瘍灌流実験系 / ヒト腫瘍細胞 / アンチセンスオリゴヌクレオチド / ドラッグデリバリーシステム / 固形腫瘍 / tumor necrosis factor / scavenger receptor / cellular uptake / 活性化 / ポリアニオン / インターロイキン-6 / 腫瘍壊死因子 / スカベンジャー受容体 / secretion polarity / interferon / LLC-PK_1 cells / MDCK cells / Pam-T cells / Caco-2 cells / epithelial cells / gene transfer / カチオン性リポソーム / 分泌タンパク / Caco-2 / 分泌方向性 / LLC-PK_1細胞 / MDCK細胞 / Pam-T細胞 / Caco-2細胞 / 消化管上皮細胞 / 遺伝子導入 / Sugar-recognition system / Dclivery systems / Liver / Pharmacokinetics / In vivo disposition / Antisense oligonucleotide / phosphorothioate / c-myc / クリアランス / poly(L-lysine) / 糖鎖認識機構 / ファーマコキネティクス / 細胞内トラフィッキング / TLR3 / ワクチン / アジュバント / 腫瘍組織関連マクロファージ / IDO-1 / 非ウィルスベクター / 非ウイルスベクター / ベクター開発 / 薬動学解析 / 膜透過ペプチド / DNA ワクチン / 抗原デリバリー / T細胞活性化 / CD86 / CD80 / shRNA発現ベクター / p-糖タンパク / in vitro / in vivo / siRNA / P-Glycoprotein / トランスポーター / マイクロスフェアー / がん治療 / マウスモデル / 肝転移 / スカベンジャーレセプター / リポソーム … More Except Principal Investigator DDS / プロドラッグ / エキソソーム / ターゲティング / 細胞治療 / ドラッグデリバリー / 高分子化プロドラッグ / 化学修飾 / acyclovir / ドラッグデリバリーシステム / 吸収促進剤 / 経皮吸収 / モーメント解析 / 抗癌剤 / イメージング / 核酸 / 体内動態 / ハイドロゲル / 活性酵素 / 活性酸素 / 遺伝子治療 / 臓器潅流実験 / 血中滞留性 / ホスファチジルセリン / 細胞外小胞 / Antibody Conjugate / Macromolecular Prodrug / Lipophilic Prodrug / Moment Analysis / Isolated Tumor Preparation / Organ Perfusion Experiment / Tissue Transport / Chemotherapy / 癌病巣モデル / 薬物組織移行性 / 抗体結合体 / 脂溶性プロドラッグ / モ-メント解析 / 単離腫瘍標本 / 臓器灌流実験 / 組織移行性 / 化学療法 / Superoxide Dismutase / Receptor-mediated Transport / Dextran / Polyethyleneglycol / Macromolecular Modification / Electric Charge / Chemical Modification / Peptide Drug / 体内挙動 / ウリカーゼ / 大豆トリプシンインヒビター / ス-パ-オキサイドジスムタ-ゼ / レセプタ-仲介エンドサイトシス / デキストラン / ポリエチレングリコ-ル / 高分子化修飾 / 電荷 / ペプチド性医薬品 / membrane-fusogenic peptides / glycosylated macromolecules / glycosylated liposomes / liver targeting / plasmid DNA / non-viral vectors / gene therapy / エンドサイトーシス / ガラクトース受容体 / カオチン性リポソーム / コレステロール / ポリカチオン / カチオン性リポソーム / DNAプラスミド / 動態発現相関 / 膜融合ペプチド / 糖修飾高分子 / 糖修飾リポソーム / 肝臓ターゲティング / プラスミドDNA / 非ウィルス性ベクター / tacrolimus / macromolecular prodrug / superoxide disumutase / reactive oxygen species / tissue damage / chemical modification / immunosuppressant / organ transplantation / マクロファージ / 細胞傷害 / タクロリムス / SOD / 細胞障害 / 免疫抑制剤 / 臓器移植 / physicochemical properties / skin permeability / skin diffusion model / prodrug / penetration enhancer / transdermal therapeutic / percutaneous absorption / 物理化学的特性 / 皮膚透過性 / 皮膚拡散モデル / 経皮治療システム / Cultured cells / Organ perfusion experiment / Organ clearance / Micropaticulate carrier system / Macromolecular carrier system / Targeting / Drug delivery system / 製剤特性 / 培養細胞 / 臓器潅流実験系 / 臓器クリアランス / 微粒子性運搬体システム / 高分子運搬体システム / Drug Delivery System / In vitro diffusion experiments / Drug lipophilicity / Skin penetration / Absorption enhancer / Fast inverse Laplace transformation / Diffusion theory / Skin model / Percutaneous absorption / in vitro拡散実験 / 脂溶性 / 皮膚透過 / 高速ラプラス逆変換 / 拡散理論 / 皮膚モデル / マイトマイシンC / 腫癌組織灌流 / 腫瘍移行性 / 癌化学療法 / SELEX法 / ラジオアイソトープ / 抗原 / DNA / 移植 / 幹細胞 / スフェロイド / ルシフェラーゼ / PEG修飾 / 細胞スフェロイド / 細胞個性 / 体内分布 / siRNA / CpG / ナノ粒子 / 酸化ストレス / ステルス化 / デリバリー / デイバリー / 高血糖 / 癌転移 / カタラーゼ / 腫瘍抗原 / 細胞障害性T細胞 / 腫瘍免疫 / 細胞ワクチン / 遺伝子導入 / インターヘェロン-γ / 薬物送達システム / 糖鎖認識機構 / モノクロ-ナル抗体 / 高分子運搬体 / 微粒子性運搬体 / 細胞培養 / タ-ゲティング Less

Development of vaccines based on the maximization of immune function and control of pharmacokinetics of extracellular vesicles derived from dendritic cellsPrincipal Investigator
- Principal Investigator
  
  Takakura Yoshinobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
Development of nose to brain delivery method using extracellular vesicles.Principal Investigator
- Principal Investigator
  
  Takakura Yoshinobu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University
Analysis of naturally stealth exosome and its application as drug delivery carrier
- Principal Investigator
  
  Takahashi Yuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kyoto University
Development of in vivo gene therapy using exosomes loading immunomodulatory moleculesPrincipal Investigator
- Principal Investigator
  
  Takakura Yoshinobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
Development of cytokine gene therapy with high therapeutic index by systemic regulation of transgene expression and biological response.Principal Investigator
- Principal Investigator
  
  Takakura Yoshinobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of therapeutic systems based on three-dimensional DNA nanostructures
- Principal Investigator
  
  Nishikawa Makiya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of DDS applicable for immune therapy by using self-assembling RNA sponge particlePrincipal Investigator
- Principal Investigator
  
  Takakura Yoshinobu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Efficient induction of in vivo RNA interference by designing exosome-tropic siRNA derivatives
- Principal Investigator
  
  Takahashi Yuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Development of microtissue therapeutic system based on mixed multicellular spheroids
- Principal Investigator
  
  NISHIKAWA Makiya
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Optimization of cytokine gene therapy based on the regulation of transcription/translation, pharmacokinetics, and cellular response.Principal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of target-specific multifunctional exosomes loaded with RNA drugs
- Principal Investigator
  
  TAKAHASHI Yuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Development of nano-sized DDS for nucleic acid drugs based on polypod-like structured nucleic acids
- Principal Investigator
  
  NISHIKAWA Makiya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of targeted cell therapeutic systems based on cell characteristics
- Principal Investigator
  
  NISHIKAWA Makiya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
一回の投与で繰り返しタンパク質を供給可能なオンデマンド型遺伝子治療システムの開発Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Design and delivery of plasmid vector for spatiotemporal control of the expression of therapeutic protein and siRNAPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
遺伝子発現再活性化現象を利用したリピータブルタンパク質発現システムの開発Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
次世代細胞治療に向けた細胞製剤のステルス化・標的指向化
- Principal Investigator
  
  西川元也
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
インターフェロン遺伝子発現の増強・持続化による新規癌治療戦略Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
DEVELOPMENT OF CANCER CHEMO-IMMUNOTHERAPEUTIC SYSTEM USING REDOX CONTROLLABLE DDS
- Principal Investigator
  
  NISHIKAWA Makiya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of all inclusive anti tumor immunotherapy based on engineered protein and nucleic acidPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
抗原投与を全く必要としない細胞内抗原トラップ型新規腫瘍ワクチンの開発Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
RNAiによる遺伝子ノックダウンと抗原デリバリーを組み合せた新規免疫療法の確立Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Design and delivery of nucleic acid drugs for optimization of DNA vaccinationPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
プラスミド水溶液投与による高効率遺伝子導入法を利用したがんのサイトカイン療法Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
In vivo RNAiによる遺伝子ノックダウンマウス作出と薬物動態研究への応用Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Establishment of novel delivery strategies to dendritic cells and optimization of DNA vaccinationPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
プラスミド水溶液投与による高効率遺伝子導入法を利用したがんのサイトカイン療法Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of plasmid DNA delivery methods to antigen presenting cells for optimized DNA vaccinationPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
Development of local drug disposition analysis and delivery methods in human solid tumorsPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYOTO UNIVERSITY
遺伝子医薬品の体内動態および細胞取り込み機構の解明に基づくデリバリー戦略の確立Principal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
動態-発現相関の解析に基づくin vivo遺伝子導入キャリアーシステムの分子設計
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
Development of Gene Delivery Systems to Intestinal Epithelial Cells as a TargetPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
Systematic development of targeting systams for prevention of tissue damages in organ transplantation
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
IFN-γ遺伝子導入による抗腫瘍機構の解析と遺伝子治療へ向けての基礎的研究
- Principal Investigator
  
  渡辺好彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Establishment of the theory based on a skin diffusion model for the optimal design of a new approach to enhanced trandermal drug delivery
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Development of Delivery Systems for the Control of Pharmacokinetics and Intracellular Trafficking of Antisense DrugsPrincipal Investigator
- Principal Investigator
  
  TAKAKURA Yoshinobu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYOTO UNIVERSITY
遺伝子治療を目的とした核酸医薬品のデリバリーシステムの確立Principal Investigator
- Principal Investigator
  
  高倉喜信
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Establishment of Evaluation Method for Function of Drug Targeting Systems and Systematization of their Physicochemical Character-Function Relationship
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYOTO UNIVERSITY
タ-ゲティング型製剤の製剤特性ー機能相関の体系化
- Principal Investigator
  
  SEZAKI Hitoshi
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Pharmacokinetic modeling and penetration enhancement of the percutaneous drug absorption based on diffusion theory
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Control of biopharmaceutical properties of peptide drugs by chemical modification employing carbohydrates
- Principal Investigator
  
  SEZAKI Hitoshi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYOTO UNIVERSITY
Establishment of a new theory for assessment of drug disposition
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KYOTO UNIVERSITY
薬物の腫瘍移行性評価システムの開発とそれを利用したターゲティング型抗癌剤設計
- Principal Investigator
  
  瀬崎仁
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University

[Book] ナノバイオ技術と最新創薬応用研究(第5章2.核酸ナノデバイスの開発とDDS応用)2012
- Author(s)
  西川元也, 毛利浩太, 高橋有己, 高倉喜信
- Total Pages
  215
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23390010
[Book] ドラッグデリバリーシステムの新展開II(第2章2立体化によるDNAアジュバントの高機能化)2012
- Author(s)
  西川元也, 毛利浩太, 高橋有己, 高倉喜信
- Total Pages
  278
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23390010
[Book] アジュバント開発研究の新展開(4.3 CpG DNAの立体化によるアジュバント効果の増強)2011
- Author(s)
  西川元也, 高倉喜信
- Total Pages
  249
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23390010
[Journal Article] Development of enzymatic depletion methods for preparation of small extracellular vesicles with long blood-circulation half-life.2022
- Author(s)
  Kobayashi Y, Kitamura S, Takahashi Y, Takakura Y.
- Journal Title
  
  Pharm Res
  
  Volume: - Issue: 4 Pages: 855-861
- DOI
  10.1007/s11095-022-03405-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04533
[Journal Article] Development of allergic rhinitis immunotherapy using antigen-loaded small extracellular vesicles2022
- Author(s)
  Liu Wen、Ota Maki、Tabushi Mayu、Takahashi Yuki、Takakura Yoshinobu
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 345 Pages: 433-442
- DOI
  10.1016/j.jconrel.2022.03.016
- Data Source
  KAKENHI-PROJECT-21H02616
[Journal Article] Phosphatidylserine-deficient small extracellular vesicle is a major somatic cell-derived sEV subpopulation in blood2021
- Author(s)
  Matsumoto Akihiro、Takahashi Yuki、Ogata Kosuke、Kitamura Shimpei、Nakagawa Naoki、Yamamoto Aki、Ishihama Yasushi、Takakura Yoshinobu
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 8 Pages: 102839-102839
- DOI
  10.1016/j.isci.2021.102839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04533, KAKENHI-PROJECT-21H02616
[Journal Article] Development of CD40L-modified tumor small extracellular vesicles for the effective induction of anti-tumor immune response.2020
- Author(s)
  Liu W, Takahashi Y, Morishita M, Nishikawa M, Takakura Y.
- Journal Title
  
  Nanomedicine (Lond).
  
  Volume: 15 Issue: 17 Pages: 1641-1652
- DOI
  10.2217/nnm-2020-0071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02562
[Journal Article] Intracellular delivery of NF-κB inhibitor peptide utilizing small extracellular vesicles for the application of anti-inflammatory therapy.2020
- Author(s)
  Takenaka M, Takahashi Y, Takakura Y.
- Journal Title
  
  J Control Release.
  
  Volume: 328 Pages: 435-443
- DOI
  10.1016/j.jconrel.2020.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02562
[Journal Article] Antitumor immunity by small extracellular vesicles collected from activated dendritic cells through effective induction of cellular and humoral immune responses2020
- Author(s)
  Matsumoto Akihiro、Asuka Maho、Takahashi Yuki、Takakura Yoshinobu
- Journal Title
  
  Biomaterials
  
  Volume: 252 Pages: 120112-120112
- DOI
  10.1016/j.biomaterials.2020.120112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02562
[Journal Article] Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance.2019
- Author(s)
  Matsumoto A, Takahashi Y, Chang HY, Wu YW, Yamamoto A, Ishihama Y, Takakura Y.
- Journal Title
  
  J Extracell Vesicles
  
  Volume: 9 Issue: 1 Pages: 1696517-1696517
- DOI
  10.1080/20013078.2019.1696517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02562, KAKENHI-PROJECT-17J06240
[Journal Article] Preservation of exosomes at room temperature using lyophilization.2018
- Author(s)
  Charoenviriyakul C, Takahashi Y, Nishikawa M, Takakura Y.
- Journal Title
  
  Int J Pharm.
  
  Volume: 553 Issue: 1-2 Pages: 1-7
- DOI
  10.1016/j.ijpharm.2018.10.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02562
[Journal Article] Safe and effective interferon-beta gene therapy for the treatment of multiple sclerosis by regulating biological activity through the design of interferon-beta-galectin-9 fusion proteins.2018
- Author(s)
  Hamana A, Takahashi Y, Tanioka A, Nishikawa M, Takakura Y.
- Journal Title
  
  Int J Pharm
  
  Volume: 536 Issue: 1 Pages: 310-317
- DOI
  10.1016/j.ijpharm.2017.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04638
[Journal Article] In vitro and in vivo stimulation of Toll-like receptor 9 by CpG oligodeoxynucleotides incorporated into polypod-like DNA nanostructures2017
- Author(s)
  Takahashi Y, Maezawa T, Araie Y, Takahashi Y, Takakura Y, Nishikawa M
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 印刷中 Issue: 9 Pages: 2457-2462
- DOI
  10.1016/j.xphs.2017.03.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293008
[Journal Article] Amelioration of Experimental Autoimmune Encephalomyelitis in Mice by Interferon-Beta Gene Therapy, Using a Long-Term Expression Plasmid Vector.2017
- Author(s)
  Hamana A, Takahashi Y, Tanioka A, Nishikawa M, Takakura Y.
- Journal Title
  
  Mol Pharm
  
  Volume: 14 Issue: 4 Pages: 1212-1217
- DOI
  10.1021/acs.molpharmaceut.6b01093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04638
[Journal Article] Interferon-Inducible Mx Promoter-Driven, Long-Term Transgene Expression System of Interferon-β for Cancer Gene Therapy.2016
- Author(s)
  Hamana A, Takahashi Y, Nishikawa M, Takakura Y.
- Journal Title
  
  Human Gene Therapy
  
  Volume: 27 Issue: 11 Pages: 936-945
- DOI
  10.1089/hum.2016.023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04638
[Journal Article] Polypod-shaped DNAs: small angle x-ray scattering and immunostimulatory activity.2016
- Author(s)
  Sanada Y, Shiomi T, Okobira T, Tan M, Nishikawa M, Akiba I, Takakura Y, Sakurai K.
- Journal Title
  
  Langmuir
  
  Volume: 印刷中 Issue: 15 Pages: 3760-3765
- DOI
  10.1021/acs.langmuir.6b00398
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293008
[Journal Article] Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells.2016
- Author(s)
  Nishida Y, Ohtsuki S, Araie Y, Umeki Y, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M.
- Journal Title
  
  Nanomedicine: Nanotechnology, Biology and Medicine
  
  Volume: 12 Issue: 1 Pages: 123-130
- DOI
  10.1016/j.nano.2015.08.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293008, KAKENHI-PLANNED-24104002, KAKENHI-PROJECT-15H03837, KAKENHI-PROJECT-16K14033
[Journal Article] Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation.2016
- Author(s)
  Yamashita T, Takahashi Y, Nishikawa M, Takakura Y.
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics
  
  Volume: 98 Pages: 1-8
- DOI
  10.1016/j.ejpb.2015.10.017
- NAID
  120005697969
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670266
[Journal Article] Application of magnesium pyrophosphate-based sponge-like microparticles to enhance the delivery efficiency and adjuvant effects of polyriboinosinic-polyribocytidylic acid in immune cells.2016
- Author(s)
  Takagi S, Takahashi Y, Sugimura K, Nishikawa M, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 105 Issue: 2 Pages: 766-772
- DOI
  10.1016/j.xphs.2015.11.020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670013
[Journal Article] Ishii-Mizuno Y, Umeki Y, Takahashi Y, Kato Y, Takabayashi T, Fujieda S, Takakura Y, Nishikawa M. Nasal delivery of Japanese cedar pollen Cryj1 by using self-gelling immunostimulatory DNA for effective induction of immune responses in mice2015
- Author(s)
  Ishii-Mizuno Y, Umeki Y, Takahashi Y, Kato Y, Takabayashi T, Fujieda S, Takakura Y, Nishikawa M
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 200 Pages: 52-59
- DOI
  10.1016/j.jconrel.2014.12.040
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25114706, KAKENHI-PROJECT-26293008, KAKENHI-PROJECT-26293368, KAKENHI-PROJECT-15K20193, KAKENHI-PROJECT-25462660
[Journal Article] Self-assembling DNA dendrimer for effective delivery of immunostimulatory CpG DNA to immune cells2015
- Author(s)
  Kohta Mohri, Eri Kusuki, Shozo Ohtsuki, Natsuki Takahashi, Masayuki Endo, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa.
- Journal Title
  
  Biomacromolecules
  
  Volume: 16 Issue: 4 Pages: 1095-1101
- DOI
  10.1021/bm501731f
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860021, KAKENHI-PROJECT-15H03837, KAKENHI-PROJECT-26620133, KAKENHI-PROJECT-26293008, KAKENHI-PLANNED-24104002
[Journal Article] Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion2015
- Author(s)
  T. Yata, Y. Takahashi, K. Hidaka, H. Sugiyama, M. Endo, Y. Takakura, M. Nishikawa
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 14979-14979
- DOI
  10.1038/srep14979
- NAID
  120005689202
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03837, KAKENHI-PROJECT-26620133, KAKENHI-PROJECT-26293008, KAKENHI-PLANNED-24104002
[Journal Article] Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice.2015
- Author(s)
  Imai T, Takahashi Y, Nishikawa M, Kato K, Morishita M, Yamashita T, Matsumoto A, Charoenviriyakul C, Takakura Y.
- Journal Title
  
  J Extracell Vesicles.
  
  Volume: 4 Issue: 1
- DOI
  10.3402/jev.v4.26238
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670266
[Journal Article] Atomic force microscopy analysis of orientation and bending of oligodeoxynucleotides in polypod-like structured DNA.2015
- Author(s)
  Shiomi T, Tan M, Takahashi N, Endo M, Emura T, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y, Nishikawa M.
- Journal Title
  
  Nano Research
  
  Volume: 8 Issue: 12 Pages: 3764-3771
- DOI
  10.1007/s12274-015-0875-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293008, KAKENHI-PLANNED-24104002
[Journal Article] Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice.2015
- Author(s)
  Morishita M, Takahashi Y, Nishikawa M, Sano K, Kato K, Yamashita T, Imai T, Saji H, Takakura Y.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 104 Issue: 2 Pages: 705-713
- DOI
  10.1002/jps.24251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670266
[Journal Article] Optimal Arrangement of Four Short DNA Strands for Delivery of Immunostimulatory Nucleic Acids to Immune Cells2015
- Author(s)
  Shozo Ohtsuki, Noriyuki Matsuzaki, Kohta Mohri, Masayuki Endo, Tomoko Emura, Kumi Hidaka, Hiroshi Sugiyama, Yuki Takahashi, Kenichi Ishiyama, Norimitsu Kadowaki, Yoshinobu Takakura, Makiya Nishikawa.
- Journal Title
  
  Nucleic Acid Therapeutics
  
  Volume: 25 Issue: 5 Pages: 245-253
- DOI
  10.1089/nat.2014.0524
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860021, KAKENHI-PROJECT-15H03837, KAKENHI-PROJECT-26620133, KAKENHI-PROJECT-26293008, KAKENHI-PLANNED-24104002
[Journal Article] Induction of Potent Antitumor Immunity by Sustained Release of Cationic Antigen from a DNA-Based Hydrogel with Adjuvant Activity2015
- Author(s)
  Yuka Umeki, Kohta Mohri, Yohji Kawasaki, Hiroshi Watanabe, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 25 Issue: 36 Pages: 5758-5767
- DOI
  10.1002/adfm.201502139
- NAID
  120005678189
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08411, KAKENHI-PROJECT-26293008
[Journal Article] Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice2014
- Author(s)
  Kusamori K, Nishikawa M, Mizuno N, Nishikawa T, Masuzawa A, Shimizu K, Konishi S, Takahashi Y, Takakura Y
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 173 Pages: 119-124
- DOI
  10.1016/j.jconrel.2013.10.024
- NAID
  120005353503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670257
[Journal Article] Enhancement of Anticancer Effect of Interferon-y Gene Transfer against Interferon-γ-Resistant Tumor by Depletion of Tumor-Associated acrophages.2014
- Author(s)
  T. Kiyota, et al.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: (in press)(掲載確定) Issue: 5 Pages: 1542-1549
- DOI
  10.1021/mp4007216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02931, KAKENHI-PROJECT-24390008
[Journal Article] Efficient delivery of immunostimulatory DNA to mouse and human immune cells through the construction of polypod-like structured DNA2014
- Author(s)
  Uno S, Nishikawa M, Mohri K, Umeki Y, Matsuzaki N, Takahashi Y, Fujita H, Kadowaki N, Takakura Y
- Journal Title
  
  Nanomedicine
  
  Volume: 10 Issue: 4 Pages: 765-74
- DOI
  10.1016/j.nano.2013.11.017
- NAID
  120005439540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010, KAKENHI-PUBLICLY-25114706
[Journal Article] DNA nanotechnology-based development of delivery systems for bioactive compounds2014
- Author(s)
  Mohri K, Nishikawa M, Takahashi Y, Takakura Y
- Journal Title
  
  European Journal of Pharmaceutical Sciences
  
  Volume: 58 Pages: 26-33
- DOI
  10.1016/j.ejps.2014.03.002
- NAID
  120005439159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010, KAKENHI-PUBLICLY-25114706
[Journal Article] Removal of transgene-expressing cells by a specific immune response induced by sustained transgene expression.2014
- Author(s)
  Yin Y, Takahashi Y, Ebisuura N, Nishikawa M, Takakura Y.
- Journal Title
  
  J Gene Med.
  
  Volume: 16 Issue: 3-4 Pages: 97-106
- DOI
  10.1002/jgm.2763
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390008
[Journal Article] Injectable, self-geling, biodegradable, and immunomodulatory DNA hydrogel for antigell dellvery2014
- Author(s)
  Makiya Nishikawa, Kohei Ogawa, Yaka Umeki, KohtaMohri, Yohji Kawashaki, Hiroshi Watanabe, Natsuki Takahashi, Eri Kusuki, Rei Takahashi, Yuki Takahashi, Yoshinobu Takakura
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 180 Pages: 25-32
- DOI
  10.1016/j.jconrel.2014.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04049, KAKENHI-PROJECT-23390010, KAKENHI-PROJECT-24245045, KAKENHI-PUBLICLY-25114706
[Journal Article] 細胞スフェロイド化技術の開発と細胞治療への応用2013
- Author(s)
  草森浩輔、西川元也、高橋有己、高倉喜信
- Journal Title
  
  Drug Delivery System
  
  Volume: 28 Pages: 45-53
- NAID
  130003368335
- Data Source
  KAKENHI-PROJECT-23659283
[Journal Article] Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection2013
- Author(s)
  Takahashi Y, Nishikawa M, Shinotsuka H, Matsui Y, Ohara S, Imai T, Takakura Y.
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 165 Pages: 77-84
- Data Source
  KAKENHI-PROJECT-24659260
[Journal Article] Expression profile-dependent improvement of insulin sensitivity by gene delivery of interleukin-6 in a mouse model of type II diabetes.2013
- Author(s)
  H. Mukumoto, et al.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 10 Issue: 10 Pages: 3812-3821
- DOI
  10.1021/mp400288e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02931, KAKENHI-PROJECT-24390008
[Journal Article] Poly(N-isopropylacrylamide)-coatedmicrowell arrays for construction and recovery of multicellular spheroids2013
- Author(s)
  Kazunori Shimizu
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 印刷中 Issue: 6 Pages: 695-699
- DOI
  10.1016/j.jbiosc.2012.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659283, KAKENHI-PROJECT-25670257
[Journal Article] Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection.2013
- Author(s)
  Takahashi Y, Nishikawa M, Shinotsuka H, Matsui Y, Ohara S, Imai T, Takakura Y.
- Journal Title
  
  Journal of Biotechnology
  
  Volume: 165 Issue: 2 Pages: 77-84
- DOI
  10.1016/j.jbiotec.2013.03.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659260
[Journal Article] Small-molecule-induced clustering of heparan sulfate promotes cell adhesion2013
- Author(s)
  Takemoto N, Suehara T, Frisco HL, Sato S, Sezaki T, Kusamori K, Kawazoe Y, Park SM, Yamazoe S, Mizuhata Y, Inoue R, Miller GJ, Hansen SU, Jayson GC, Gardiner JM, Kanaya T, Tokitoh N, Ueda K, Takakura Y, Kioka N, Nishikawa M, Uesugi M.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 135 Issue: 30 Pages: 11032-11039
- DOI
  10.1021/ja4018682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510277, KAKENHI-PROJECT-24245046, KAKENHI-PROJECT-24510316, KAKENHI-PROJECT-25670257
[Journal Article] Design and development of nanosized DNA assemblies in polypod-like structures as efficient vehicles for immunostimulatory CpG motifs to immune cells2012
- Author(s)
  Mohri K, Nishikawa M, Takahashi N, Shiomi T, Matsuoka N, Ogawa K, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y
- Journal Title
  
  ACS Nano
  
  Volume: 6 Issue: 7 Pages: 5931-5940
- DOI
  10.1021/nn300727j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010, KAKENHI-PLANNED-24104002, KAKENHI-PROJECT-24310097
[Journal Article] Constant and steady transgene expression of interferon-γby optimization of plasmid construct for safe and effective interferon-γgene therapy2012
- Author(s)
  Ando M, Takahashi Y, Nishikawa M, Watanabe Y, Takakura Y.
- Journal Title
  
  J Gene Med
  
  Volume: 14 Issue: 4 Pages: 288-295
- DOI
  10.1002/jgm.2616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009, KAKENHI-PROJECT-24390008
[Journal Article] Controlling thekinetics of interferon transgene expression lor improved gene therapy.2012
- Author(s)
  Watcharanurak K, Nishikawa M, Takahashi Y, Takakura Y.
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 20 Issue: 9 Pages: 764-769
- DOI
  10.3109/1061186x.2012.716848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390008
[Journal Article] Self-assembling CpG DNA nanoparticles for efficient antigen delivery and immunostimulation2012
- Author(s)
  Rattanakiat S, Nishikawa M, Takakura Y
- Journal Title
  
  European Journal of Pharmaceutical Sciences
  
  Volume: 47 Issue: 2 Pages: 352-358
- DOI
  10.1016/j.ejps.2012.06.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010
[Journal Article] Increased immunostimulatory activity of polypod-like structured DNA by ligation of the terminal loop structures2012
- Author(s)
  Mohri K, Takahashi N, Nishikawa M, Kusuki E, Shiomi T, Takahashi Y, Takakura Y
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 163 Issue: 3 Pages: 285-292
- DOI
  10.1016/j.jconrel.2012.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010
[Journal Article] Fibronectin inhibits cytokine production induced by CpG DNA in macrophages without direct binding to DNA2012
- Author(s)
  Yoshida H, Nishikawa M, Yasuda S, Toyota H, Kiyota T, Takahashi Y, Takakura Y
- Journal Title
  
  Cytokine
  
  Volume: 60 Issue: 1 Pages: 162-170
- DOI
  10.1016/j.cyto.2012.06.237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390010
[Journal Article] Control of Spatiotemporal Distribution of Interferon γ by Genetically Fusing Functional Peptides2012
- Author(s)
  M. Ando, et al.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Issue: 12 Pages: 1399-1406
- DOI
  10.1248/yakushi.12-00235-4
- NAID
  130002489537
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2012-12-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02931, KAKENHI-PROJECT-24390008
[Journal Article] Saturation of transgene protein synthesis from mRNA in cells producing a large number of transgene mRNA2011
- Author(s)
  Takahashi Y, Nishikawa M, Takiguchi N, Suehara T, Takakura Y.
- Journal Title
  
  Biotechnol Bioeng
  
  Volume: 108 Issue: 10 Pages: 2380-2389
- DOI
  10.1002/bit.23179
- NAID
  120005593565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] 5'-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages.2011
- Author(s)
  Yoshida H., Nishikawa M., Takakura Y., et al.
- Journal Title
  
  European Journal of Immunology
  
  Volume: 41 Pages: 425-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] 5'-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages2011
- Author(s)
  Yoshida H, Nishikawa M, Kiyota T, Uno S, Toyota H, Takahashi R, Narita M, Takakura Y.
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Issue: 2 Pages: 425-436
- DOI
  10.1002/eji.201040396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009, KAKENHI-PROJECT-21590438
[Journal Article] Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice2011
- Author(s)
  Yoshida H, Nishikawa M, Kiyota T, Toyota H, Takakura Y.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 51 Issue: 2 Pages: 424-431
- DOI
  10.1016/j.freeradbiomed.2011.04.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009, KAKENHI-PROJECT-23390010
[Journal Article] Positive correlation between the generation of reactive oxygen species and activation/reactivation of transgene expression after hydrodynamic injections into mice.2011
- Author(s)
  Takiguchi N., Takahashi Y., Nishikawa M., Takakura Y., et al.
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 28 Pages: 702-711
- NAID
  120004754348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659009
[Journal Article] Prolonged circulation half-life of interferonγactivity by gene delivery of interferonγ-serum albumin fusion protein in mice2011
- Author(s)
  Miyakawa N, Nishikawa M, Takahashi Y, Ando M, Misaka M, Watanabe Y, Takakura Y.
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Issue: 6 Pages: 2350-2357
- DOI
  10.1002/jps.22473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Inhibition of nuclear delivery of plasmid DNA and transcription by interferonγ: hurdles to be overcome for sustained gene therapy2011
- Author(s)
  Zang L, Nishikawa M, Machida K, AndoM, Takahashi Y, Watanabe Y, Takakura Y.
- Journal Title
  
  Gene Ther
  
  Volume: 18 Issue: 9 Pages: 891-897
- DOI
  10.1038/gt.2011.35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Induction of Tumor-specific Immune Response by Gene Transfer of Hsp70-cell-penetrating Peptide Fusion Protein to Tumors in Mice2010
- Author(s)
  Nishikawa M, Otsuki T, Ota A, Guan X, Takemoto S, Takahashi Y, Takakura Y.
- Journal Title
  
  Mol Ther
  
  Volume: 18 Issue: 2 Pages: 421-428
- DOI
  10.1038/mt.2009.203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Injection site-dependent induction of immune response by DNA vaccine : comparison of skin and spleen as a target for vaccination.2010
- Author(s)
  Guan X., Nishikawa M., Takakura Y., et al.
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: 12 Pages: 301-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors.2010
- Author(s)
  Takahashi Y.Nishikawa M., Takakura Y., et al.
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: 12 Pages: 739-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Persistent interferon transgene expression by RNA interference-mediated silencing of interferon receptors2010
- Author(s)
  Takahashi Y, Vikman E, Nishikawa M, Ando M, Watanabe Y, Takakura Y.
- Journal Title
  
  J Gene Med
  
  Volume: 12 Issue: 9 Pages: 739-746
- DOI
  10.1002/jgm.1493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Sustained exogenous expression of therapeutic levels of IFN-γ ameliorates atopic dermatitis in NC/Nga mice via Th1 polarization.2010
- Author(s)
  Hattori K., Nishikawa M., Takahashi Y., Takakura Y., et al.
- Journal Title
  
  Journal of Immunology
  
  Volume: 184 Pages: 2729-2735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Sustained exogenous expression of therapeutic levels of IFN-gamma ameliorates atopic dermatitis in NC/Nga mice via Th1 polarization2010
- Author(s)
  Hattori K, Nishikawa M, Watcharanurak K, Ikoma A, Kabashima K, Toyota H, Takahashi Y, Takahashi R, Watanabe Y, Takakura Y.
- Journal Title
  
  J Immunol
  
  Volume: 184 Issue: 5 Pages: 2729-2735
- DOI
  10.4049/jimmunol.0900215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009, KAKENHI-PROJECT-21590438
[Journal Article] Development of a novel Hsp70-based DNA vaccine as a multifunctional antigen delivery system2010
- Author(s)
  Yamaoka A, Guan X, Takemoto S, Nishikawa M, Takakura Y.
- Journal Title
  
  J Control Release
  
  Volume: 142 Issue: 3 Pages: 411-415
- DOI
  10.1016/j.jconrel.2009.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Injection site-dependent induction of immune response by DNA vaccine : comparison of skin and spleen as a target for vaccination2010
- Author(s)
  Guan X, Nishikawa M, Takemoto S, Ohno Y, Yata T, Takakura Y.
- Journal Title
  
  J Gene Med
  
  Volume: 12 Issue: 3 Pages: 301-309
- DOI
  10.1002/jgm.1432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Enhanced generation of cytotoxic T lymphocytes by increased cytosolic delivery of MHC class I epitope fused to mouse heat shock protein 70 via polyhistidine conjugation2009
- Author(s)
  Takemoto S, Nishikawa M, Otsuki T, Yamaoka A, Maeda K, Ota A, Takakura Y.
- Journal Title
  
  J Control Release
  
  Volume: 135 Issue: 1 Pages: 11-18
- DOI
  10.1016/j.jconrel.2008.11.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase.2009
- Author(s)
  Yata T, Nishikawa M, Nishizaki C, Oku M, Yurimoto H, Sakai Y, Takakura Y.
- Journal Title
  
  Free Radic Biol Med 47(12)
  
  Pages: 1772-1778
- NAID
  120001815090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390010
[Journal Article] Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis.2009
- Author(s)
  Nishikawa M, Hashida M, Takakura Y.
- Journal Title
  
  Adv Drug Delivery Rev 61(4)
  
  Pages: 319-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390010
[Journal Article] Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination2009
- Author(s)
  Isaji K, Kawase A, Matono M, Guan X, Nishikawa M, Takakura Y.
- Journal Title
  
  Journal of Controlled Release 135
  
  Pages: 227-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Nonviral vector-mediated RNA interference : its gene silencing characteristics and important factors to achieve RNAi-based gene therapy Adv Drug Deliv Rev2009
- Author(s)
  Takahashi Y, Nishikawa M, Takakura Y.
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 61 Issue: 9 Pages: 760-766
- DOI
  10.1016/j.addr.2009.04.006
- ISSN
  0169-409X
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors2009
- Author(s)
  Takahashi Y, Yamaoka K, Nishikawa M, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences 98
  
  Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors2009
- Author(s)
  Takahashi Y, Yamaoka K, Nishikawa M, Takakura Y.
- Journal Title
  
  J Pharm Sci
  
  Volume: 98 Issue: 1 Pages: 74-80
- DOI
  10.1002/jps.21398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Enhanced CTL response by controlled intracellular trafficking of antigen in dendritic cells following DNA vaccination2009
- Author(s)
  Isaji K, Kawase A, Matono M, Guan X, Nishikawa M, Takakura Y.
- Journal Title
  
  J Control Release
  
  Volume: 135 Issue: 3 Pages: 227-233
- DOI
  10.1016/j.jconrel.2009.01.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390009
[Journal Article] Heat shock protein derivatives for delivery of antigens to antigen presenting cells.2008
- Author(s)
  Nishikawa M, Takemoto S, Takakura Y.
- Journal Title
  
  International Journal of Pharmaceutics 354
  
  Pages: 23-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Gene silencing of ss-catenin in melanoma cells retards their growth but promotes the formation of pulmonary metastasis in mice2008
- Author(s)
  Takahashi Y, Nishikawa M, Suehara T, Takiguchi N, Takakura Y.
- Journal Title
  
  International Journal of Cancer 123
  
  Pages: 2315-2320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Inhibition of tumor cell growth in the liver by RNA interference mediated suppression of HIF-1α expression in tumor cells and hepatocytes2008
- Author(s)
  Takahashi Y, Nishikawa M, Takakura Y.
- Journal Title
  
  Gene Therapy 15
  
  Pages: 572-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice.2008
- Author(s)
  Kako K, Nishikawa M, Yoshida H, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation2008
- Author(s)
  Nishikawa M, Matono M, Rattanakiat S, Matsuoka N, Takakura Y.
- Journal Title
  
  Immunology 124
  
  Pages: 247-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Heat shock protein derivatives for delivery of antigens to antigen presenting cells2008
- Author(s)
  Nishikawa M, Takemoto S, Takakura Y.
- Journal Title
  
  International Journal of Pharmaceutics 354
  
  Pages: 23-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice2008
- Author(s)
  Kako K, Nishikawa M, Yoshida H, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences 97
  
  Pages: 3074-3083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Cellular activation by plasmid DNA in various macrophages in primary culture2008
- Author(s)
  Yoshida H, Nishikawa M, Yasuda S, Mizuno Y, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences 97
  
  Pages: 4575-4585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Heat shock protein derivatives for delivery of antigens to antigen presenting cells.2008
- Author(s)
  Nishikawa M, Takemoto S, Takakura Y.
- Journal Title
  
  International Journal of Pharmaceutics 354
  
  Pages: 23-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659039
[Journal Article] Unique cytokine production profile following stimulation with DNA in macrophages from NZB/W F1 mice2008
- Author(s)
  Ogawa Y, Yoshinaga T, Nishikawa M, Takakura Y.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 31
  
  Pages: 1244-1249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Cellular activation by plasmid DNA in various macrophages in primary culture.2008
- Author(s)
  Yoshida H, Nishikawa M, Yasuda S, Mizuno Y, Takakura Y.
- Journal Title
  
  Journal of Pharmaceutical Sciences
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Hsp-based tumor vaccines: state-of-the-art and future directions.2007
- Author(s)
  Takakura Y, Takemoto S, Nishikawa M.
- Journal Title
  
  Current Opinion in Molecular Therapeutics 9
  
  Pages: 385-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Induction of antigen specific cytotoxic T lymphocytes by immunization with negatively charged soluble antigen through scavenger receptor mediated delivery2007
- Author(s)
  Yamasaki Y, Ikenaga T, Ohtsuki T, Nishikawa M, Takakura Y.
- Journal Title
  
  Vaccine 25
  
  Pages: 85-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] DNA and its cationic lipid complexes induce CpG motif-dependent activation of murine dendritic cells.2007
- Author(s)
  Takaharu Yoshinaga, Key Yasuda, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura
- Journal Title
  
  Immunology 120
  
  Pages: 295-302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390041
[Journal Article] Hsp-based tumor vaccines: state-of-the-art and futuredirections.2007
- Author(s)
  Takakura Y, Takemoto S, Nishikawa M.
- Journal Title
  
  Current Opinion in Molecular Therapeutics 9
  
  Pages: 385-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659039
[Journal Article] Hsp-based tumor vaccines : state-of-the-art and future directions2007
- Author(s)
  Takakura Y, Takemoto S, Nishikawa M.
- Journal Title
  
  Current Opinion in Molecular Therapeutics 9
  
  Pages: 385-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Induction of antigen-specific cytotoxic T lymphocytes by immunization with negatively-charged soluble antigen through scavengreceptor-mediated delivery2007
- Author(s)
  Yamasaki Y, Ikenaga T, Ohtsuki T, Nishikawa M, Takakura Y.
- Journal Title
  
  Vaccine 25
  
  Pages: 85-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Plasmid DNA uptake and subsequent cellular activation characteristics in human monocyte-derived cells in primary culture.2007
- Author(s)
  Yuga Fukuhara, Tomoyuki Naoi, Yoshiyuki Ogawa, Makiya Nishikawa, Yoshinobu Takakura.
- Journal Title
  
  Journal of Pharmaceutical Sciences 96
  
  Pages: 1576-1584
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390041
[Journal Article] Enhanced antigen-specific antibody production following polyplex-based DNA vaccination via the intradermal route in mice.2006
- Author(s)
  Atsushi Kawase, Keiko Isaji, Ayumi Yamaoka, Naoki Kobayashi, Makiya Nishikawa, Yoshinobu Takakura
- Journal Title
  
  Vaccine 24
  
  Pages: 5535-5545
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390041
[Journal Article] Manipulation of local disposition and gene expression characteristics of plasmid DNA following intramuscular administration by complexation with cationic macromolecule2005
- Author(s)
  Atsushi Kawase, Naoki Kobayashi, Keiko Isaji, Makiya Nishikawa, Yoshinobu Takakura
- Journal Title
  
  Int.J.Pharm. 293
  
  Pages: 291-301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390048
[Journal Article] Nonviral vector-mediated RNA interference: its gene silencing characteristics and important factors to achieve RNAi-based gene therapy
- Author(s)
  Takahashi Y, Nishikawa M, Takakura Y
- Journal Title
  
  Advanced Drug Delivery Reviews in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] TLR9-depdendent systemic interferon-ss production by intravenous injection of plasmid DNA/cationic liposome complex in mice
- Author(s)
  Yoshida H, Nishikawa M, Yasuda S, Mizuno Y,Toyota H, Kiyota T, Takahashi R, Takakura Y.
- Journal Title
  
  Journal of Gene Medicine (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390041
[Journal Article] Inhibition of surgical trauma-enhanced peritoneal dissemination of tumor cells by human catalase derivatives in mice.
- Author(s)
  Nishizaki C, Nishikawa M, Yata T, Yamada T, Takahashi Y, Oku M, Yurimoto H, Sakai Y, Nakanishi K, Takakura Y.
- Journal Title
  
  Free Radic Biol Med (印刷中)
  
  Pages: 2011-2011
- NAID
  120003255726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390010
[Presentation] CpG DNA修飾した細胞外小胞を徐放可能なゼラチン微粒子の開発2023
- Author(s)
  安江和佳奈、塩野光希、高橋有己、高倉喜信
- Organizer
  日本DDS学会第39回学術集会
- Data Source
  KAKENHI-PROJECT-21H02616
[Presentation] 細胞外小胞エクソソーム：新たなDDS開発のプラットフォームとなり得るか？2022
- Author(s)
  高倉喜信
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19908
[Presentation] 持続的な細胞外小胞放出を可能とするメタクリル酸修飾ゼラチン微粒子の開発2022
- Author(s)
  高橋有己、塩野光希、高倉喜信
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21H02616
[Presentation] Investigation of in vivo behavior of extracellular vesicles with different sizes after intraduodenal administration2022
- Author(s)
  Yuki Kobayashi, Momoko Naiki, Ayane Yabuta Yuki Takahashi, Yoshinobu Takakura.
- Organizer
  Globalization of Pharmaceutics Education Network 2022 (GPEN2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04533
[Presentation] マウス血漿中において長期血中滞留性を示す細胞外小胞の発見とその体内動態解析2021
- Author(s)
  高橋有己、松本明宏、北村慎平、高倉喜信
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H04533
[Presentation] 抗炎症治療を目的とした細胞外小胞によるマクロファージへのIL4デリバリー2020
- Author(s)
  竹中美佐子、高橋有己、薮田文寧、高倉喜信
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] がんワクチン療法への適用を目的としたInterferon-γ搭載がん細胞由来exosome の開発2019
- Author(s)
  仲川直輝, 高橋有己, 高倉喜信
- Organizer
  に翻訳学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] 血液中の内因性エキソソームの挙動解析のための標識法開発と薬物速度論的解析に基づく内因性エキソソーム濃度維持機構の解明2019
- Author(s)
  松本明宏、高橋有己、山本晶、高倉喜信
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] Development of Interferon γ-loaded tumor cell-derived extracellular vesicles applicable to cancer vaccine therapy.2019
- Author(s)
  Nakagawa N, Takahashi Y, Takakura Y.
- Organizer
  International Society for Extracellular Vesicles 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] 免疫活性化能を有する抗原搭載樹状細胞由来エキソソームを利用した効果的ながんワクチン療法の開発2019
- Author(s)
  飛鳥真帆、松本明宏、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] エクソソームの標識技術とドラッグデリバリー応用の最前線2018
- Author(s)
  高倉喜信
- Organizer
  第36回物性物理化学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] Development of Exosome Assembly Formed by Utilization of DNA Hybridization and its Application for Cancer Vaccine.2018
- Author(s)
  Matsumoto A, Takahashi Y, Ariizumi R, Nishikawa M, Takakura Y.
- Organizer
  Globalization of Pharmaceutics Education Network 2018 (GPEN2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02562
[Presentation] 抗原内包免疫刺激性DNAハイドロゲルへの免疫細胞の組み込みによる抗腫瘍免疫の増強2017
- Author(s)
  梅木佑夏、高橋有己、高倉喜信、西川元也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 青色光受容体VIVIDを利用したインターフェロンβの活性制御2017
- Author(s)
  谷岡あかね、高橋有己、濵名温志、西川元也、高倉喜信
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-15H04638
[Presentation] Sustained expression system of interferon-beta by using interferon-inducible Mx promoter for interferon-beta gene therapy.2016
- Author(s)
  Atsushi Hamana, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura
- Organizer
  Globalization of Pharmaceutics Education Network 2016
- Place of Presentation
  Lawrence, KS, USA
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04638
[Presentation] 光熱免疫療法のための複合材料型DNAハイドロゲルの開発2016
- Author(s)
  譚萌萌、矢田智也、村上達也、中辻博貴、高橋有己、高倉喜信、西川元也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 三次元構造化DNAの免疫細胞および非免疫細胞との相互作用解析2016
- Author(s)
  大槻昇三，高橋有己，井上貴雄，高倉喜信，西川元也
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川・横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] ヒトMSR-1導入HEK-Blue hTLR9細胞を用いた核酸医薬の免疫活性評価2016
- Author(s)
  大槻昇三、高橋有己、梅村圭祐、井上貴雄、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第2年会
- Place of Presentation
  東京
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] インターフェロン-β持続発現ベクターの開発とがん遺伝子治療への適用2016
- Author(s)
  濵名温志、高橋有己、西川元也、高倉喜信
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（横浜県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04638
[Presentation] Elucidation of factors determining the cell distribution in artificially fabricated mixed multicellular spheroids for improved insulin secretion2016
- Author(s)
  Yuya Mizukami, Makiya Nishikawa, Yuki Takahashi, Kazunori Shimizu, Satoshi Konishi, Yoshinobu Takakura
- Organizer
  Globalization of Pharmaceutics Education Network 2016 (GPEN2016)
- Place of Presentation
  Lawrence, KS, USA
- Year and Date
  2016-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 免疫刺激性DNAハイドロゲルからのカチオン化抗原の徐放化による抗腫瘍免疫の増強2016
- Author(s)
  梅木佑夏、高橋有己、高倉喜信、西川元也
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] ナノ構造化核酸を基盤とする核酸医薬のデリバリー戦略2016
- Author(s)
  西川元也、高倉喜信
- Organizer
  日本核酸医薬学会第2年会
- Place of Presentation
  東京
- Year and Date
  2016-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] アジュバント活性を有するDNAハイドロゲルからの抗原徐放化による抗腫瘍免疫の効率的誘導2016
- Author(s)
  西川元也、高橋有己、高倉喜信
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] Enhanced Activity of Immunosuppressive Oligodeoxynucleotides by Incorporating into Hexapod-like Nanostructured DNA2016
- Author(s)
  Yuki Araie, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa
- Organizer
  The 1st Workshop for Japan-Korea Young Scientists on Pharmaceutics
- Place of Presentation
  京都
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 生体内安定性の向上を目的としたGカルテット構造を組み込んだDNAハイドロゲルの開発と機能評価2015
- Author(s)
  梅木佑夏、高橋有己、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都・京都）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] インターフェロンβ持続発現プラスミドベクターの構築とがん遺伝子治療への適用2015
- Author(s)
  濵名温志、高橋有己、西川元也、高倉喜信
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都府　京都市）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15H04638
[Presentation] 免疫刺激性DNAで構成したDNAハイドロゲルからの抗原徐放化による抗腫瘍免疫誘導の増強．2015
- Author(s)
  梅木佑夏、西川元也、毛利浩太、高橋有己、高倉喜信
- Organizer
  遺伝子・デリバリー研究会第15回シンポジウム
- Place of Presentation
  京都薬科大学（京都・京都）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 核酸医薬のDDSへの応用を目的とした体内動態制御型核酸搭載exosomeの開発2015
- Author(s)
  高橋有己、西川元也、高倉喜信
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] 原子間力顕微鏡観察によるpolypodna中のDNA配向性の解明2015
- Author(s)
  譚　萌萌、塩見朋紀、高橋夏樹、遠藤政幸、江村智子、日高久美、杉山　弘、高橋有己、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都・京都）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] ナノ構造体化を利用した免疫刺激性DNAによるヒト細胞からのサイトカイン産生の増強2015
- Author(s)
  大槻昇三、高橋有己、井上貴雄、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都・京都）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] ピロリン酸マグネシウム微粒子を用いた免疫アジュバントのデリバリー2015
- Author(s)
  高木翔一、高橋有己、杉村佳那子、西川元也、高倉喜信
- Organizer
  第65回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪大谷大学（大阪府富田林市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26670013
[Presentation] 免疫細胞への選択的デリバリーを目的としたナノ構造化DNAの開発2015
- Author(s)
  大槻昇三、西川元也、Tatu Lajunen、毛利浩太、井上貴雄、高橋有己、高倉喜信
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 抗腫瘍免疫の増強を目的としたCpG DNA修飾癌細胞由来exosomeの開発2015
- Author(s)
  森下将輝、高橋有己、西川元也、高倉喜信
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県　長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] インターフェロン応答性Mxプロモーターを利用したインターフェロンβ持続発現プラスミドベクターの開発2015
- Author(s)
  濵名温志、高橋有己、西川元也、高倉喜信
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15H04638
[Presentation] RCA法および酵素消化の組み合わせによる自己ゲル化多足型DNA構造体の効率的増幅2015
- Author(s)
  矢田智也、高橋有己、譚　萌萌、日高久美、遠藤政幸、杉山　弘、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都・京都）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] DNAハイドロゲルを利用したCpG DNAの経膣投与による膣粘膜免疫の持続的活性化．2015
- Author(s)
  野村大貴、高橋有己、高倉喜信、西川元也
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ（京都・京都）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] Exosome回収方法がexosomeの特性に及ぼす影響の評価2015
- Author(s)
  山下拓真、高橋有己、西川元也、高倉喜信
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県　長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] Streptavidin-biotin結合を利用したexosomeの放射標識によるexosome体内動態定量的解析法の開発2014
- Author(s)
  森下将輝、高橋有己、佐野紘平、西川元也、佐治英郎、高倉喜信
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学工学部2号館（熊本市）
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Streptavidin-biotin結合を利用したexosomeの放射標識によるexosome体内動態定量的解析法の開発2014
- Author(s)
  森下将輝、高橋有己、佐野紘平、西川元也、佐治英郎、高倉喜信
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] DNAナノテクノロジーを基盤とする免疫アジュバント・抗原徐放システムの開発2014
- Author(s)
  西川元也、高倉喜信
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 核酸搭載ピロリン酸マイクロスポンジを利用した免疫アジュバントの開発2014
- Author(s)
  高木翔一、高橋有己、杉村佳那子、西川元也、高倉喜信
- Organizer
  日本バイオマテリアル学会第9回関西若手研究発表会
- Place of Presentation
  京都大学船井哲良記念講堂（京都）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PROJECT-26670013
[Presentation] DNA ナノテクノロジーを基盤とする免疫アジュバント・抗原徐放システムの開発2014
- Author(s)
  西川元也, 高倉喜信
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] xosomeを基盤とするDDS開発を指向した体内動態評価システムの開発2013
- Author(s)
  高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] 静電的相互作用を利用した免疫刺激性DNA ハイドロゲルからの抗原徐放化による抗腫瘍免疫の効率的誘導2013
- Author(s)
  梅木佑夏, 西川元也, 毛利浩太, 高橋有己, 高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 高速原子間力顕微鏡観察によるpolypodna中のDNA配向性の解明2013
- Author(s)
  塩見朋紀、西川元也、高橋夏樹、遠藤政幸、日高久美、杉山　弘、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Upregulation of indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer and its effects on tumor growth in mice.2013
- Author(s)
  Kanitta Watcharanurak, Lei Zang, Makiya Nishikawa, Kayo Yoshinaga, Yuki Takahashi, Yasuko Yamamoto, Kuniaki Saito, Yuki Murakami, Yoshinobu Takakura
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市南区）
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] 核酸ナノ構造体を利用した免疫細胞への免疫抑制性オリゴヌクレオチドデリバリー2013
- Author(s)
  西田　優、西川元也、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 免疫刺激性核酸の免疫細胞への効率的デリバリーを目的とした自己会合型DNAナノ構造体の構造活性相関2013
- Author(s)
  大槻昇三、西川元也、毛利浩太、松崎憲幸、高橋有己、高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] DNA ハイドロゲルを基盤とした抗原デリバリーシステムの開発2013
- Author(s)
  梅木佑夏, 西川元也, 小川耕平, 毛利浩太, 高橋有己, 高倉喜信
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 細胞スフェロイドサイズの制御に基づく肝細胞および癌細胞機能制御2013
- Author(s)
  西川智子、草森浩輔、西川元也、水野成美、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] 免疫刺激性核酸の免疫細胞への効率的デリバリーを目的とした自己会合型DNA ナノ構造体の構造活性相関2013
- Author(s)
  大槻昇三, 西川元也, 毛利浩太, 松崎憲幸, 高橋有己, 高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 核酸ナノ構造体を利用した免疫細胞への免疫抑制性オリゴヌクレオチドデリバリー2013
- Author(s)
  西田優, 西川元也, 高橋有己, 高倉喜信
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 混合型細胞スフェロイドの構築によるインスリン産生細胞からのインスリン放出性の増強2013
- Author(s)
  水野成美、草森浩輔、西川元也、西川智子、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] 血管内皮細胞との混合型細胞スフェロイドの開発によるインスリン産生細胞からのインスリン放出性の増強2013
- Author(s)
  水野成美、草森浩輔、西川元也、西川智子、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] exosomeを基盤とするDDS開発を指向した体内動態評価システムの開発2013
- Author(s)
  高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市南区）
- Invited
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] 蛍光標識exosomeを利用した細胞とexosomeとの相互作用解析2013
- Author(s)
  加藤佳奈、大原早織、高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Takumi 型核酸ナノ構造体を利用した免疫細胞への免疫抑制性オリゴ核酸のデリバリー2013
- Author(s)
  西田優, 西川元也, 遠藤政幸, 杉山弘, 高橋有己, 高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] DNAハイドロゲルを基盤とした抗原デリバリーシステムの開発2013
- Author(s)
  梅木佑夏、西川元也、小川耕平、毛利浩太、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Takumi 型核酸ナノ構造体の開発と免疫抑制性オリゴヌクレオチドデリバリーへの応用2013
- Author(s)
  西田優, 西川元也, 高橋有己, 高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 今井貴文、高橋有己、西川元也、高倉喜信Gaussia Luciferase-Lactadherin 融合タンパク質を利用したexosomeの体内動態評価法の開発2013
- Author(s)
  今井貴文、高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市南区）
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Gaussia Luciferaseを利用したエクソソーム標識法の開発によるエクソソーム体内動態解析2013
- Author(s)
  今井貴文、高橋有己、西川元也、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（名古屋市中村区）
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Gaussia Luciferaseを利用したエクソソーム標識法の開発によるエクソソーム体内動態解析2013
- Author(s)
  今井貴文、高橋有己、西川元也、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Takumi型核酸ナノ構造体を利用した免疫細胞への免疫抑制性オリゴ核酸のデリバリー2013
- Author(s)
  西田　優、西川元也、遠藤政幸、杉山　弘、高橋有己、高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 自己組織化デンドリマー型DNAを基盤とする免疫細胞指向性核酸DDSの開発2013
- Author(s)
  楠木絵理、西川元也、毛利浩太、高橋夏樹、遠藤政幸、日高久美、杉山　弘、高橋有己、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 核酸医薬の効率的な免疫細胞へのターゲティングを目的とした自己組織化デンドリマー型DNAの開発2013
- Author(s)
  楠木絵理、西川元也、毛利浩太、高橋夏樹、遠藤政幸、日高久美、杉山　弘、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 自己組織化デンドリマー型DNA を基盤とする免疫細胞指向性核酸DDS の開発2013
- Author(s)
  楠木絵理, 西川元也, 毛利浩太, 高橋夏樹, 遠藤政幸, 日高久美, 杉山弘, 高橋有己, 高倉喜信
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 蛍光標識exosomeを利用した細胞とexosomeとの相互作用解析2013
- Author(s)
  加藤佳奈、大原早織、高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市南区）
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Gaussia Luciferase-Lactadherin融合タンパク質を利用したexosomeの体内動態評価法の開発2013
- Author(s)
  今井貴文、高橋有己、西川元也、高倉喜信
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] 核酸医薬の効率的な免疫細胞へのターゲティングを目的とした自己組織化デンドリマー型DNA の開発2013
- Author(s)
  楠木絵理, 西川元也, 毛利浩太, 高橋夏樹, 遠藤政幸, 日高久美, 杉山弘, 高橋有己, 高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Takumi型核酸ナノ構造体の開発と免疫抑制性オリゴヌクレオチドデリバリーへの応用2013
- Author(s)
  西田　優、西川元也、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 静電的相互作用を利用した免疫刺激性DNAハイドロゲルからの抗原徐放化による抗腫瘍免疫の効率的誘導2013
- Author(s)
  梅木佑夏、西川元也、毛利浩太、高橋有己、高倉喜信
- Organizer
  第23回アンチセンスシンポジウム
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Removal of transgene-expressing cells by transgene-specific immune response induced by sustained transgene expression.2013
- Author(s)
  Yalei Yin, Norifumi Ebisuura, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市南区）
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] 高速原子間力顕微鏡観察によるpolypodna 中のDNA 配向性の解明2013
- Author(s)
  塩見朋紀, 西川元也, 高橋夏樹, 遠藤政幸, 日高久美, 杉山弘, 高橋有己, 高倉喜信
- Organizer
  第29回日本DDS 学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Micromolding技術を利用した細胞スフェロイドのサイズ制御と細胞機能に及ぼすサイズの影響の解明2013
- Author(s)
  西川智子、草森浩輔、西川元也、水野成美、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] Development of self-assembling and immunostimulatory dendrimer-like DNA for stimulation of immune cells2013
- Author(s)
  Nishikawa M, Kusuki E, Mohri K, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y
- Organizer
  9th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Naples, Italy
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 注射投与可能なDNAハイドロゲルのレオロジー解析と抗原デリバリー2012
- Author(s)
  梅木佑夏, 西川元也, 小川耕平, 毛利浩太, 高橋夏樹, 川崎洋志, 渡辺宏, 高橋有己, 高倉喜信
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Effects of highly upregulated indoleamine 2,3-dioxygenase 1 on anti-tumor activity of interferonγ gene transfer in tumor-bearing mice.2012
- Author(s)
  Watcharanurak K, Takakura Y, et al.
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] Visualization of polypod-like structured DNA, polypodna, and its application as nano-sized immunomodulator and building block for versatile DNA hydrogel2012
- Author(s)
  Nishikawa M, Endo M, Sugiyama H, Takahashi Y, Takakura Y
- Organizer
  OTS Meeting 2012
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 遺伝子・核酸医薬のデザインとデリバリーの最適化2012
- Author(s)
  高倉喜信、高橋有己、西川元也
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台市民会館(宮城県)(招待講演)
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] 多足型核酸構造体-ポリポドナ-の設計と構造・機能解析2012
- Author(s)
  西川元也, 毛利浩太, 高橋夏樹, 楠木絵理, 塩見朋紀, 小川耕平, 梅木佑夏, 遠藤政幸, 杉山弘, 渡辺宏, 高橋有己, 高倉喜信
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2012
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 細胞表面接着型インターフェロンを利用した標的特異的作用型遺伝子治療システムの開発2012
- Author(s)
  高橋有己、安藤満、西川元也、渡部好彦、高倉喜信
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  武庫川女子大学(兵庫県)(招待講演)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] ヘパラン硫酸結合ドメインの融合による細胞表面付着型インターフェロンγの開発と遺伝子デリバリーによる疾患治療2012
- Author(s)
  安藤満、高橋有己、西川元也、渡部好彦、高倉喜信
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都大学薬学部(京都府)
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] 細胞接着を促進する合成低分子化合物 adhesamine 誘導体の利用による細胞治療効果の増強2012
- Author(s)
  草森浩輔、西川元也、高橋有己、山添紗有美、上杉志成、高倉喜信
- Organizer
  第34回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都大学薬学部、京都府
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] マウスにおけるRNA干渉効果の定量的解析法の開発2012
- Author(s)
  高橋有己、松井由梨子、西川元也、高倉喜信
- Organizer
  日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] ポリジメチルシロキサン製マイクロポケットを利用した細胞スフェロイドの作製2012
- Author(s)
  草森浩輔、西川元也、水野成美、清水一憲、小西　聡、豊田健太郎、稲垣暢也、高橋有己、高倉喜信
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] ポリ-N-イソプロピルアクリルアミド被覆ポリジメチルシロキサン基板を用いた細胞スフェロイドの作製2012
- Author(s)
  舛澤暁、西川元也、草森浩輔、水野成美、清水一憲、小西聡、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第27 年会
- Place of Presentation
  神戸国際会議場、兵庫県
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] 体内動態と生体応答の制御に基づくインターフェロン癌遺伝子治療法の開発2012
- Author(s)
  高橋有己、西川元也.高倉喜信
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場(兵庫県)(招待講演)
- Year and Date
  2012-05-26
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] ポリジメチルシロキサン製マイクロポケットを利用した細胞スフェロイドの作製2012
- Author(s)
  草森浩輔、西川元也、水野成美、清水一憲、小西聡、豊田健太郎、稲垣暢也、高橋有己、高倉喜信
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  北海道大学、北海道
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] Development of Uniformly Sized Insulin-Producing Multicellular Spheroids for the Treatment of Type 1 Diabetes2012
- Author(s)
  Kosuke Kusamori, Makiya Nishikawa, Narumi Mizuno, Tomoko Nishikawa, Kazunori Shimizu, Satoshi Konishi, Yuki Takahashi, Yoshinobu Takakura
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都大学薬学部、京都府
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] 注射投与可能なDNA ハイドロゲルを利用した抗原デリバリーシステムの開発2012
- Author(s)
  高橋夏樹, 西川元也, 毛利浩太, 小川耕平, 梅木佑夏, 楠木絵理, 高橋有己, 高倉喜信
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 多足型構造DNA によるマウスおよびヒト免疫細胞の活性化2012
- Author(s)
  松崎憲幸, 西川元也, 宇野翔大, 毛利浩太, 日高久美, 遠藤政幸, 杉山弘, 高橋有己, 高倉喜信
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Self-assembling nano-sized dendrimer-like DNA for efficient delivery of immunostimulatory CpG DNA to immune cells2012
- Author(s)
  Kusuki E, Nishikawa M, Mohri K, Takahashi N, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Cellular Uptake Mechanism of Fluorescently Labeled Exosomes.2012
- Author(s)
  Saori Ohara, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura.
- Organizer
  第６回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都大学薬学部（京都府）
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] Cellular Uptake Mechanism of Fluorescently Labeled Exosomes2012
- Author(s)
  Saori Ohara, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura.
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659260
[Presentation] 1 型糖尿病治療を目的とした・細胞スフェロイドの作製2012
- Author(s)
  草森浩輔、西川元也、水野成美、清水一憲、小西聡、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第27 年会
- Place of Presentation
  神戸国際会議場、兵庫県
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] 注射可能なDNA ハイドロゲルを利用した抗原デリバリーシステムの開発2011
- Author(s)
  小川耕平, 西川元也, 毛利浩太, 楠木絵里, 高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 安定性改善を目的としたloop構造を含む多足型DNA-polypodna-の開発2011
- Author(s)
  高橋夏樹, 西川元也, 毛利浩太, 楠木絵里, 高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター(大阪府)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 免疫活性型核酸の立体化による活性増強とDDS開発2011
- Author(s)
  西川元也、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀(東京都)(招待講演)
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 酵素反応を必要としないDNAハイドロゲルの開発2011
- Author(s)
  毛利浩太, 西川元也, 小川耕平, 高橋夏樹, 楠木絵里, 高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター(大阪府)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 安定性改善を目的としたloop 構造を含む多足型DNA -polypodna-の開発2011
- Author(s)
  高橋夏樹, 西川元也, 毛利浩太, 楠木絵里, 高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Kinetic comparison of gene silencing profile of siRNA and shRNA-expressing plasmid DNA in vivo2011
- Author(s)
  Takahashi Y, Matsui Y, Nishikawa M, Takakura Y
- Organizer
  7th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  The Royal Library (Copenhagen, Denmark)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] 酵素反応を必要としないDNA ハイドロゲルの開発2011
- Author(s)
  毛利浩太, 西川元也, 小川耕平, 高橋夏樹, 楠木絵里, 高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Development of anticancer DNA nanopods as immunostimulatory delivery systems for anticancer agents2011
- Author(s)
  Nishikawa M, Takahashi Y, Takakura Y
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 注射可能なDNAハイドロゲルを利用した抗原デリバリーシステムの開発2011
- Author(s)
  小川耕平, 西川元也, 毛利浩太, 楠木絵里高橋有己, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター(大阪府)
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 細胞機能促進化合物の利用による骨髄由来細胞の皮膚損傷治療効果の増強2011
- Author(s)
  草森浩輔、西川元也、高橋有己、山添紗有美、上杉志成、高倉喜信
- Organizer
  日本薬剤学会第26 年会
- Place of Presentation
  タワーホール船堀、東京都
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] Kinetic comparison of gene silencing profile of siRNA and shRNA-expressing plasmid DNA in vivo2011
- Author(s)
  Takahashi Y, Matsui Y, Nishikawa M, Takakura Y.
- Organizer
  7th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  The Royal Library(Copenhagen, Denmark)
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] 抗原タンパク質の発現プロファイル依存的な抗原特異的免疫応答の解析2011
- Author(s)
  戎浦規文, 高橋有己, 西川元也, 高倉喜信
- Organizer
  第21アンチセンスシンポジウム+第11回遺伝子・デリバリー研究会シンポジウム合同シンポジウム
- Place of Presentation
  大阪大学コンベンションセンター(大阪府)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] 核酸を基盤としたナノメディシンのデザインとデリバリー2011
- Author(s)
  高倉喜信
- Organizer
  第20回DDSカンファランス
- Place of Presentation
  静岡県コンベンションアーツセンター(静岡県)(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] 核酸を基盤としたナノメディシンのデザインとデリバリー2011
- Author(s)
  高倉喜信
- Organizer
  第20回DDSカンファランス
- Place of Presentation
  静岡県コンベンションアーツセンター(静岡県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] Development of DNA nanogels and hydrogels as injectable delivery systems for CpG DNA and other nucleic acid-based drugs2011
- Author(s)
  Nishikawa M, Mohri K, Ogawa K, Takahashi N, Takahashi Y, Takakura Y
- Organizer
  7th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 免疫活性型核酸の立体化による活性増強とDDS 開発2011
- Author(s)
  西川元也, 高橋有己, 高倉喜信
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] 細胞機能促進化合物の利用による骨髄由来細胞の皮膚創傷治療効果の増強2011
- Author(s)
  草森浩輔、西川元也、高橋有己、山添紗有美、上杉志成、高倉喜信
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23659283
[Presentation] Development of anticancer DNA nanopods as immunostimulatory delivery systems for anticancer agents2011
- Author(s)
  Nishikawa M, Takahashi Y, Takakura Y
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知芸術文化センター(愛知県)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23390010
[Presentation] Interferonγ-mediated inhibition of nuclear entry of plasmid vector and mRNA transcription from the vector : an obstacle for repeated injections of interferonγ-expressing plasmid vector2010
- Author(s)
  Zang L, Nishikawa M, Machida K, Ando M, Takahashi Y, Takakura Y.
- Organizer
  Pharmaceutical Sciences World Congress
- Place of Presentation
  Morial convention center(New Orleans, USA)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] Design and gene delivery of mouse interferonγgenetically fused with mouse serum albumin2010
- Author(s)
  Miyakawa N, Nishikawa M, Takahashi Y, Watanabe Y, Takakura Y.
- Organizer
  Pharmaceutical Sciences World Congress
- Place of Presentation
  Morial convention center(New Orleans, USA)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] Development of DNA Nano Assemblies with Enhanced Immunostimulatory Activity2009
- Author(s)
  Rattanakiat S, Nishikawa M, Takakura Y.
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Contradictory effects of gene silencing of b-catenin in melanoma cells on proliferation and metastasis2009
- Author(s)
  高橋有己, 西川元也, 高倉喜信
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390009
[Presentation] CpGモチーフを含まないプラスミドDNA/リポソーム複合体によるマクロファージからのサイトカイン産生機構の解析2008
- Author(s)
  豊田敬康、安田幸代、西川元也、吉田寛幸、高倉喜信
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Optimization of Design and Delivery of Plasmid Vector for Interferon GeneTherapy2008
- Author(s)
  Takakura Y
- Organizer
  2008 KCRS Annual Conference: Research Networking for FutureTherapy
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-20015022
[Presentation] Interferon Gene Therapy against Metastatic Cancer2008
- Author(s)
  Takakura Y, Nishikawa M
- Organizer
  Ehrlich II -2nd World Conference on Magic Bullets
- Place of Presentation
  Nurnberg, Germany
- Data Source
  KAKENHI-PROJECT-20015022
[Presentation] ホスホロチオエートDNAの組み込みによるY型DNAの免疫賦活化能の増強2008
- Author(s)
  松岡奈穂、西川元也、Sakulrat Rattanakiat、高倉喜信
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] 免疫・化学療法に向けた短鎖DNA を基盤とするDNAナノ粒子・ハイドロゲル開発2008
- Author(s)
  水野友美子、西川元也、的野光洋、Sakulrat Rattanakiat、Dan Luo、舟橋久景、高倉喜信
- Organizer
  第18回アンチセンスシンポジウム
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] DNA 刺激によるマクロファージ活性化に対するフィブロネクチンの細胞活性化抑制機構の解析2008
- Author(s)
  吉田寛幸、西川元也、豊田敬康、安田幸代、水野友美子、高倉喜信
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] DNA-based Nanoassembly Formation for Enhanced Immunostimulatory Activity of Oligodeoxynucleotides2008
- Author(s)
  Rattanakiat S, Nishikawa M, Takakura Y.
- Organizer
  第24回日本DDS学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Enhanced immunostimulatory activity of oligodeoxynucleotides by cholesterol conjugation2008
- Author(s)
  Rattanakiat S, Nishikawa M, Takakura Y.
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Optimization of Design and Delivery of Plasmid Vector for Interferon Gene Therapy2008
- Author(s)
  Takakura Y.
- Organizer
  2008 KCRS Annual Conference : Research Networking for Future Therapy
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] マウスにおけるDNAに対する免疫応答プロファイルの評価.2008
- Author(s)
  吉田寛幸、西川元也、安田幸代、水野友美子、豊田敬康、高倉喜信
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Enhanced immunostimulatory activity of oligodeoxynucleotides by cholesterol conjugation.2008
- Author(s)
  Rattanakiat S, Nishikawa M, Takakura Y.
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] β-catenin遺伝子発現抑制による癌細胞増殖抑制と肺転移の亢進2008
- Author(s)
  末原徹也、高橋有己、西川元也、滝口直美、高倉喜信
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] DNAを基盤とする抗癌剤デリバリー・免疫活性化システムの開発2008
- Author(s)
  水野友美子、西川元也、直井智幸、高倉喜信
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] DNAを基盤とする抗癌剤デリバリー・免疫活性化システムの開発.2008
- Author(s)
  水野友美子、西川元也、直井智幸、高倉喜信
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Unique Property of IFN-ss Production upon Intravenous Injection of CpG Plasmid DNA/Cationic Liposome Complex2008
- Author(s)
  Yoshida H, Nishikawa M, Yasuda S, Mizuno Y, Toyota H, Takakura Y
- Organizer
  The 4th Seoul Kyoto Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] マウスにおけるDNAに対する免疫応答プロファイルの評価2008
- Author(s)
  吉田寛幸、西川元也、安田幸代、水野友美子、豊田敬康、高倉喜信
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] MHCクラスI・II両エピトープ搭載型Hsp70抗原デリバリーシステムの開発.2007
- Author(s)
  関心、竹本誠二、西川元也、太田淳、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] DNAワクチンの投与部位依存的免疫応答の誘導.2007
- Author(s)
  矢田智也、西川元也、大野祐司、関心、竹本誠二、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation.2007
- Author(s)
  Rattanakiat S, Matono M, Nishikawa M, Takakura Y.
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] MHCクラスI・II両エピトープ搭載型Hsp70抗原デリバリーシステムの開発.2007
- Author(s)
  関心、竹本誠二、西川元也、太田淳、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19659039
[Presentation] DNAワクチンの投与部位依存的免疫応答の誘導.2007
- Author(s)
  矢田智也、西川元也、大野祐司、関心、竹本誠二、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19659039
[Presentation] DNA ワクチンの投与部位依存的免疫応答の誘導2007
- Author(s)
  矢田智也、西川元也、大野祐司、関心、竹本誠二、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] プラスミドDNA に対する炎症応答の評価とその制御2007
- Author(s)
  吉田寛幸、西川元也、安田幸代、水野友美子、光井優、高倉喜信
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  さいたま市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] MHCクラスI・II両エピトープ搭載型Hsp70抗原デリバリーシステムの開発2007
- Author(s)
  関心、竹本誠二、西川元也、太田淳、高倉喜信
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] プラスミドDNAに対する炎症応答の評価とその制御.2007
- Author(s)
  吉田寛幸、西川元也、安田幸代、水野友美子、光井優、高倉喜信
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  さいたま市
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Enhanced immunostimulatory activity of oligodeoxynucleotides by Y-shape formation2007
- Author(s)
  Rattanakiat S, Matono M, Nishikawa M, Takakura Y.
- Organizer
  第23回日本DDS学会学術集会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-19390041
[Presentation] Streaptavidin-biotin結合に基づいたexosome放射標識法によるexosome体内動態の定量的解析
- Author(s)
  森下将輝、高橋有己、佐野紘平、西川元也、佐治英郎、高倉喜信
- Organizer
  日本DDS学会第30年会
- Place of Presentation
  慶應義塾大学（東京）
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] 混合スフェロイドにおける細胞局在化の原因究明
- Author(s)
  水上優哉、西川元也、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎
- Year and Date
  2015-05-21 – 2015-05-23
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] 混合細胞スフェロイドを用いた糖尿病治療効果の増強
- Author(s)
  田中悠太郎、水野成美、水上優哉、西川元也、西川智子、草森浩輔、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] Optimization of DNA nanostructure for delivery of nucleic acid drugs to immune cells
- Author(s)
  Ohtsuki S, Nishikawa M, Matsuzaki N, Mohri K, Endo M, Hidaka K, Sugiyama H, Takahashi Y, Takakura Y
- Organizer
  GPEN 2014
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2014-08-27 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 小角X線散乱による構造解析に基づく多足型DNAの構造活性相関の解明
- Author(s)
  塩見朋紀、西川元也、高橋夏樹、真田雄介、櫻井和朗、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] SELEX法を利用したexosome移行性RNAの探索
- Author(s)
  篠塚春香、高橋有己、加藤佳奈、西川元也、高倉喜信
- Organizer
  日本DDS学会第30年会
- Place of Presentation
  慶應義塾大学（東京）
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] DNAナノテクノロジーを基盤とする核酸医薬のデリバリー
- Author(s)
  西川元也、高倉喜信
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] 多足型DNAのpod数依存的な溶液内立体構造と細胞取り込みとの相関解析
- Author(s)
  塩見朋紀、西川元也、毛利浩太、真田雄介、櫻井和朗、高橋有己、高倉喜信
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2014
- Place of Presentation
  東京
- Year and Date
  2014-09-08 – 2014-09-09
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] ピロリン酸マグネシウム粒子を用いたワクチンシステムの開発
- Author(s)
  高木翔一、高橋有己、杉村佳那子、西川元也、高倉喜信
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（神戸）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670013
[Presentation] DNAハイドロゲルを用いたCryj1の経鼻デリバリーによるスギ花粉症に対する免疫療法の開発
- Author(s)
  水野友美子、梅木佑夏、高橋有己、高倉喜信、西川元也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] マクロファージを用いた細胞スフェロイドの作製
- Author(s)
  田中悠太郎、西川元也、荻野悠加、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] 免疫刺激性DNAの免疫細胞へのデリバリーのためのDNAナノ構造体の設計
- Author(s)
  大槻昇三、西川元也、毛利浩太、松崎憲幸、遠藤政幸、日高久美、杉山　弘、高橋有己、高倉喜信
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26293008
[Presentation] Immunological removal of transgene-expressing cells after in vivo gene transfer.
- Author(s)
  Yalei Yin, Norifumi Ebisuura, Yuki Takahashi, Makiya Nishikawa, Yoshinobu Takakura.
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（さいたま市）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-24390008
[Presentation] 静脈内投与されたB16BL6由来エキソソームのマウスにおけるマクロファージ依存的消失挙動
- Author(s)
  山下拓真、今井貴文、高橋有己、森下将輝、西川元也、高倉喜信
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮ソニックシティビル（さいたま市）
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] 静脈内投与された細胞の肺への集積の定量的評価と制御
- Author(s)
  田中悠太郎、荻野悠加、西川元也、西川智子、高橋有己、高倉喜信
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-02 – 2015-07-03
- Data Source
  KAKENHI-PROJECT-25670257
[Presentation] Quantitative analysis of the distribution and clearance of mouse melanoma B16-BL6-derived exosomes in mice.
- Author(s)
  Takahashi Y, Imai T, Nishikawa M, Kato K, Morishita M, Takakura Y.
- Organizer
  International Society for Extracellular Vesicles 2014
- Place of Presentation
  Rotterdam(オランダ)
- Year and Date
  2014-04-30 – 2014-05-04
- Data Source
  KAKENHI-PROJECT-26670266
[Presentation] 肝細胞スフェロイドのサイズ制御による細胞機能の最適化
- Author(s)
  西川智子、西川元也、草森浩輔、水野成美、清水一憲、小西　聡、高橋有己、高倉喜信
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25670257

1. NISHIKAWA Makiya (40273437)

# of Collaborated Projects: 23 results

# of Collaborated Products: 208 results
2. TAKAHASHI Yuki (00547870)

# of Collaborated Projects: 13 results

# of Collaborated Products: 150 results
3. HASHIDA Mitsuru (20135594)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
4. SEZAKI Hitoshi (50025681)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMAMOTO Akira (00166779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. YAMASHITA Fumiyoshi (30243041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMAOKA Kiyoshi (50109013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YURIMOTO Hiroya (00283648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. ENDO Masayuki (70335389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. WATANABE Hiroshi (90167164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIMURA Norio (00191643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 渡辺好彦 (90109075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小形公亮 (80866781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. SATO Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 毛利浩太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 高橋玲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takakura Yoshinobu 高倉 喜信

TAKAKURA Yoshinobu 高倉 喜信

高倉 善信 タカクラ ヨシノブ

高倉 喜信

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Development of vaccines based on the maximization of immune function and control of pharmacokinetics of extracellular vesicles derived from dendritic cellsPrincipal Investigator

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Development of nose to brain delivery method using extracellular vesicles.Principal Investigator

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Development of in vivo gene therapy using exosomes loading immunomodulatory moleculesPrincipal Investigator

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Development of cytokine gene therapy with high therapeutic index by systemic regulation of transgene expression and biological response.Principal Investigator

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Development of DDS applicable for immune therapy by using self-assembling RNA sponge particlePrincipal Investigator

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Optimization of cytokine gene therapy based on the regulation of transcription/translation, pharmacokinetics, and cellular response.Principal Investigator

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一回の投与で繰り返しタンパク質を供給可能なオンデマンド型遺伝子治療システムの開発Principal Investigator

Principal Investigator

Takakura Yoshinobu 高倉喜信

TAKAKURA Yoshinobu 高倉喜信

高倉善信タカクラヨシノブ

高倉喜信