FUJII Masahiro 藤井雅寛

… Alternative Names

藤井雅見フジイマサヒロ

藤井雅寛フジイマサヒロ

Less

Researcher Number	30183099
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2023 – 2025: 新潟大学, 医歯学総合研究科, 客員研究員 2005 – 2022: 新潟大学, 医歯学系, 教授 2003 – 2004: 新潟大学, 大学院・医歯学総合研究科, 教授 2001: 新潟大学, 大学医院・医歯学総合研究科, 教授 2001: Graduate School of Medical and Dental Sciences, Niigata University, Professor, 大学院・医歯学総合研究科, 教授 … More 2000: 新潟大学, 医学部, 教授 1998: 新潟大学, 医学部, 教授 1996 – 1997: 東京医科歯科大学, 医学系研究科, 助教授 1996: 東京医科歯科大学, 医学部, 助教授 1995: 東京医科歯科大学, 助教授 1994: 金沢大, がん研, 助手 1990 – 1993: 金沢大学, がん研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Hematology / Basic Section 49010:Pathological biochemistry-related / Virology / Pathological medical chemistry / Virology / General medical chemistry Except Principal Investigator Virology / Basic Section 52050:Embryonic medicine and pediatrics-related / Hematology
Keywords	Principal Investigator HTLV-1 / Tax / ATL / ウイルス / アポトーシス / USP10 / ストレス顆粒 / NF-kB / G3BP1 / G3BP2 … More / AP-1 / PDZ / アルツハイマー病 / シヌクレイン / パーキンソン病 / 活性酸素 / アグリソーム / Virus / IL-2 / 白血病 / 発ガン / 免疫不全 / 細胞死 / 凝集体 / レビー小体 / タウ / TDP-43 / 癌 / NFAT / CD45RO / stress granules / ROS / 感染症 / 微生物 / NF-kB2 / HTLV-2 / Dlg / トランスフォメーション / 感染 / 成人T細胞白血病 / HTLV / Fas / HIV / エイズ / 神経細胞 / aggresome / リン酸化 / p62 / Keap1 / Nrf2 / α-シヌクレイン / 神経毒性 / オリゴマー / ユビキチン / αシヌクレイン / ｐ６２ / NRF2 / ドーパミン / ALS / アルツハイマー / 蛋白質凝集体 / 脳神経疾患 / オートファジー / 老化 / 脳・神経 / 神経科学 / ストレス / SCF / 造血幹細胞 / leukemia / サイトカイン / NF-AT / Oncogenesis / Leukemia / Apoptosis / 発がん / T-cell / oncogenesis / adult T-cell leukemia / CD45 / 潜伏感染 / T細胞 / 亜ヒ酸 / ＡＴＬ / 亜砒酸 / 免疫学的シナプス / Ezrin / 癌抑制遺伝子 / Scribble / 染色体転座 / 遺伝子変異 / Rel / WNK1 / CD4 / NF-Kb / NIK / 分子生物学 / サイクリン / SDF-1 / CD8 / 自己免疫 / HAM / HTLV-I / プロモーター / c-Fos / v-Src / c-jun / fra-1 / CArG box / SRF / cーjun / APー1 / 癌遺伝子 / cーfos / HTLVー1 / 転写因子 … More Except Principal Investigator サーベイランス / 遺伝子解析 / 分子疫学 / 薬剤耐性 / ミャンマー / インフルエンザ / ATL / Tax / HTLV-1 / 感染動物モデル / ウイルス受容体ノックインマウス / 重症ヒトパレコウイルス3型感染症 / ヒトパレコウイルス / 血液腫瘍抑制因子 / 細胞増殖抑制 / 血球細胞系 / 新規RasGAP / 血液系腫瘍 / 血液細胞 / RasGAP / 遺伝子プロファイル / 腫瘍抑制因子 / 骨髄系細胞 / B細胞 / 血液腫瘍 / RASAL3 / 地理的伝播 / 地理伝播 / 国際研究者交流 / ノイラミニダーゼ阻害剤耐性 / 流行疫学 / ベトナム / マレーシア / レバノン / インフルエンザウイルス / オセルタミビル / NA遺伝子 / HA遺伝子 / 感染症疫学 / 日本 / 国際研究 / 新型インフルエンザ / ウイルス進化 / ウイルス遺伝子解析 / 流行時期 / SCIDマウス / トランスジェニックラット / トランスフォーメイション / 転写活性化因子 / HAM / HTLV-I / 転写活性化 / 成人T細胞白血病 / SRF / c-fos / 細胞性初期遺伝子 / AMF / ras / TIMP / メタロプロテア-ゼ / 浸潤 / 転移 Less

アルツハイマー病の進行期におけるUSP10を介した神経細胞死の制御機構の解明Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Niigata University
Establishment of a mouse model of human parechovirus A3 infection and elucidation of the mechanism of severe infection
- Principal Investigator
  
  渡邉香奈子
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Niigata University
神経病原性蛋白質オリゴマーの神経毒性を抑制する分子メカニズムPrincipal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Niigata University
Mechanism of inactivation of neuropathogenic protein toxicity by aggresomesPrincipal Investigator
- Principal Investigator
  
  FUJII MASAHIRO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Niigata University
Regulation mechanism of Ras signal by novel RasGAP specific to blood cells
- Principal Investigator
  
  Kousuke Saito
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
ROS production regulation by stress granulePrincipal Investigator
- Principal Investigator
  
  FUJII MASAHIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Niigata University
Crosstalk between stress granules and autophagy in protein degradationPrincipal Investigator
- Principal Investigator
  
  Fujii Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Niigata University
Regulation of antivirus innate immunity by stress granulesPrincipal Investigator
- Principal Investigator
  
  Fujii Masahiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Niigata University
Influenza virus transmission, evolution and appearance of drug resistant viruses in Asia.
- Principal Investigator
  
  SAITO Reiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Niigata University
Molecular mechanism of arsenite therapy against adult T-cell leukemiaPrincipal Investigator
- Principal Investigator
  
  FUJII Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
Influenza surveillance in Myanmar: investigations on emergence of drug resistant strains and clinical pictures of H1N1pdm09
- Principal Investigator
  
  SAITO Reiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Niigata University
サイトカイン非依存性細胞増殖のHTLV-1発がんにおける意義Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Activation of NF-kB2 in adult T-cell leukemiaPrincipal Investigator
- Principal Investigator
  
  FUJII Masahiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
PDZドメイン蛋白を介したHTLV-1発がんの悪性化機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
PDZドメイン蛋白を介したHTLV-1発がんの悪性化機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Molecular mechanism of aberrant activation of cytokine expressions and immunodeficiency by HTLV-1 infectionPrincipal Investigator
- Principal Investigator
  
  MASAHIRO Fujii
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
HTLV-1とHTLV-2の白血病発症能の違いを決める分子機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Isolation of genes encoding NF-kB activator in adult T-cell leukemiaPrincipal Investigator
- Principal Investigator
  
  FUJII Masahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
HTLV-1 TaxによるT細胞のトランスフォメーションの分子機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Molecular mechanism of the persistent infection of human T-cell leukemia virus type 1Principal Investigator
- Principal Investigator
  
  FUJII Masahiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Niigata University
ケモカインSDF-1のエイズウイルス感染抑制因子としての意義Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
HAM(HTLV-I associated myelophathy)発症の分子機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
エイズウイルスによる細胞傷害性に関与する細胞因子の同定Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
成人T細胞白血病発症に関与するウイルス感染以外の発ガン因子の同定Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
HTLV-1による細胞がん化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
細胞性初期遺伝子群の転写制御因子p67^<SRF>のHTLV-1Taxによる活性化機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
c-jun遺伝子の抑制的発現制御機構の解析Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
HTLV-1 Taxによる細胞性初期遺伝子の発現誘導機講とウイルス複製への役割
- Principal Investigator
  
  清木元治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kanazawa University
HTLVー1 Tax蛋白によるcーfos発現誘導の分子機構Principal Investigator
- Principal Investigator
  
  藤井雅寛
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University
癌遺伝子rasによる高転移性獲得過程の分子生物学的解析
- Principal Investigator
  
  清木元治
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kanazawa University

[Book] HTLV-1と疾患 (HTLV-2)2007
- Author(s)
  藤井雅寛
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18012016
[Book] ヒトT細胞白血病ウイルス(HTLV-1の分子生物学)2007
- Author(s)
  藤井雅寛
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-18012016
[Book] ヒトT細胞白血病ウイルス(HTLV-1の分子生物学)2007
- Author(s)
  藤井雅寛
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-19591099
[Book] ヒトT細胞白血病ウイルス2007
- Author(s)
  藤井雅寛
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-19591099
[Book] HTLV-1と疾患(HTLV-2)2007
- Author(s)
  藤井雅寛
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19591099
[Book] HTLV-1と疾患2007
- Author(s)
  藤井雅寛
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] USP10 Inhibits Aberrant Cytoplasmic Aggregation of TDP-43 by Promoting Stress Granule Clearance2022
- Author(s)
  Takahashi Masahiko、Kitaura Hiroki、Kakita Akiyoshi、Kakihana Taichi、Katsuragi Yoshinori、Onodera Osamu、Iwakura Yuriko、Nawa Hiroyuki、Komatsu Masaaki、Fujii Masahiro
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 42 Issue: 3
- DOI
  10.1128/mcb.00393-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K07291, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K07757, KAKENHI-PROJECT-19H03542
[Journal Article] USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity2022
- Author(s)
  Sango Junya、Kakihana Taichi、Takahashi Masahiko、Katsuragi Yoshinori、Anisimov Sergei、Komatsu Masaaki、Fujii Masahiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 1 Pages: 101448-101448
- DOI
  10.1016/j.jbc.2021.101448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16142, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-20K07757, KAKENHI-PROJECT-21K07291, KAKENHI-PROJECT-23K24091
[Journal Article] The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-432021
- Author(s)
  Kakihana Taichi、Takahashi Masahiko、Katsuragi Yoshinori、Yamashita Shun-Ichi、Sango Junya、Kanki Tomotake、Onodera Osamu、Fujii Masahiro
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 7 Pages: 102733-102733
- DOI
  10.1016/j.isci.2021.102733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-20K07757, KAKENHI-PROJECT-21K07291
[Journal Article] Novel FMRP interaction networks linked to cellular stress2020
- Author(s)
  Taha MS, Haghighi F, Stefanski A, Nakhaei-Rad S, Kazemein Jasemi NS, Al Kabbani MA, Gorg B, Fujii M, Lang PA, Haussinger D, Piekorz RP, Stuhler K, Ahmadian MR.
- Journal Title
  
  FEBS J
  
  Volume: 288(3) Issue: 3 Pages: 837-860
- DOI
  10.1111/febs.15443
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03432
[Journal Article] Antitumor effect of sugar-modified cytosine nucleosides on growth of adult T-cell leukemia cells in mice2020
- Author(s)
  Maeda N, Matsuda A, Otsuguro S, Takahashi M, Fujii M, Maenaka K.
- Journal Title
  
  Vaccines
  
  Volume: 8 Issue: 4 Pages: 658-658
- DOI
  10.3390/vaccines8040658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07523, KAKENHI-PROJECT-19H03432
[Journal Article] The regulation of NDRG2 expression during ATLL development after HTLV-1 infection.2019
- Author(s)
  Ichikawa T, Nakahata S, Fujii M, Iha H, Shimoda K, Morishita K.
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis
  
  Volume: 1865 Issue: 10 Pages: 2633-2646
- DOI
  10.1016/j.bbadis.2019.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K09931
[Journal Article] USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells2019
- Author(s)
  Piatnitskaia S, Takahashi M, Kitaura H, Katsuragi Y, Kakihana T, Zhang L, Kakita A, Iwakura Y, Nawa H, Miura T, Ikeuchi T, Hara T, Fujii M
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10591-10591
- DOI
  10.1038/s41598-019-47033-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07698, KAKENHI-PROJECT-19K17822, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-19H03542, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K07380, KAKENHI-PROJECT-17K09918
[Journal Article] Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.2019
- Author(s)
  Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 3491-3491
- DOI
  10.1038/s41598-019-39424-7
- NAID
  120006825908
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07238, KAKENHI-PROJECT-16K07120, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600
[Journal Article] G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP102019
- Author(s)
  Anisimov S, Takahashi M, Kakihana T, Katsuragi Y, Kitaura H, Zhang L, Kakita A, Fujii M.
- Journal Title
  
  Sci Rep
  
  Volume: 9(1) Issue: 1 Pages: 12896-12896
- DOI
  10.1038/s41598-019-46237-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17822, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-19H03542, KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K07380, KAKENHI-PROJECT-17K09918
[Journal Article] MAGI-1 expression is decreased in several types of human T-cell leukemia cell lines, including adult T-cell leukemia.2018
- Author(s)
  Kozakai T, Takahashi M, Higuchi M, Hara T, Saito K, Tanaka Y, Masuko M, Takizawa J, Sone H, Fujii M
- Journal Title
  
  International Journal of Hematology
  
  Volume: 107(3) Issue: 3 Pages: 337-344
- DOI
  10.1007/s12185-017-2359-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09918, KAKENHI-PROJECT-16K15502, KAKENHI-PROJECT-17K14989, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-15K09469, KAKENHI-PROJECT-16K09822
[Journal Article] Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP.2018
- Author(s)
  Naito T, Yasunaga JI, Mitobe Y, Shirai K, Sejima H, Ushirogawa H, Tanaka Y, Nakamura T, Hanada K, Fujii M, Matsuoka M, Saito M.
- Journal Title
  
  Retrovirology
  
  Volume: 15 Issue: 1 Pages: 72-72
- DOI
  10.1186/s12977-018-0454-x
- NAID
  120006847301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K07166, KAKENHI-PROJECT-17K09170, KAKENHI-PROJECT-18K07541, KAKENHI-PROJECT-18H02420
[Journal Article] USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.2018
- Author(s)
  Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.
- Journal Title
  
  iScience
  
  Volume: 30 Pages: 433-450
- DOI
  10.1016/j.isci.2018.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09822, KAKENHI-PROJECT-17K07380, KAKENHI-PROJECT-17K09918, KAKENHI-PROJECT-16K15502, KAKENHI-PROJECT-16H06276
[Journal Article] Sox2-dependent inhibition of p21 is associated with poor prognosis of endometrial cancer2017
- Author(s)
  Yamawaki K, Ishiguro T, Mori Y, Yoshihara K, Suda K, Tamura R, Yamaguchi M, Sekine M, Kashima K, Higuchi M, Fujii M, Okamoto K, Enomoto T
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 4 Pages: 632
- DOI
  10.1111/cas.13196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01581, KAKENHI-PROJECT-26293073, KAKENHI-PROJECT-15K14390, KAKENHI-PROJECT-15K20132, KAKENHI-PROJECT-16K15502, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-17H04336, KAKENHI-PROJECT-16H06267, KAKENHI-PROJECT-15K09469, KAKENHI-PROJECT-15K10707
[Journal Article] Induction of Cell Death by Human T-cell Leukemia Virus Type 1 Tax in a Cell Cycle-Dependent Manner.2016
- Author(s)
  Mizuguchi M, Sasaki Y, Hara T, Higuchi M, Tanaka Y, Funato N, Tanaka N, Fujii M, Nakamura M.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 2 Pages: 0148217-0148217
- DOI
  10.1371/journal.pone.0148217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11004, KAKENHI-PROJECT-15K21003, KAKENHI-PROJECT-25670774, KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15502
[Journal Article] USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells.2016
- Author(s)
  Higuchi M, Kawamura H, Matsuki H, Hara T, Takahashi M, Saito S, Saito K, Jiang S, Naito M, Kiyonari H, Fujii M.
- Journal Title
  
  Stem Cell Reports
  
  Volume: ７ Issue: 6 Pages: 1116-1129
- DOI
  10.1016/j.stemcr.2016.11.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-15K21003, KAKENHI-PROJECT-15K09469, KAKENHI-PROJECT-16K15502
[Journal Article] Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB.2016
- Author(s)
  Motai Y, Takahashi M, Takachi T, Higuchi M, Hara T, Mizuguchi M, Aoyagi Y, Terai S, Tanaka Y, Fujii M.
- Journal Title
  
  Virus Genes.
  
  Volume: 52 Issue: 1 Pages: 4-13
- DOI
  10.1007/s11262-015-1277-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-15K21003, KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-16K15502
[Journal Article] RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells.2015
- Author(s)
  Saito S, Kawamura T, Higuchi M, Kobayashi T, Yoshita-Takahashi M, Yamazaki M, Abe M, Sakimura K, Kanda Y, Kawamura H, Jiang S, Naito M, Yoshizaki T, Takahashi M, Fujii M.
- Journal Title
  
  Eur J Immunol.
  
  Volume: in press Issue: 5 Pages: 1512-1523
- DOI
  10.1002/eji.201444977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-26460990, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-15H04704
[Journal Article] Kruppel-like factor 2 represses transcription of the telomerase catalytic subunit hTERT in human T cells.2015
- Author(s)
  Hara T, Mizuguchi M, Fujii M, Nakamura M.
- Journal Title
  
  J Biol Chem
  
  Volume: 290(14) Issue: 14 Pages: 8758-8763
- DOI
  10.1074/jbc.m114.610386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21003, KAKENHI-PROJECT-15H04704
[Journal Article] Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development.2015
- Author(s)
  Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 12841-12841
- DOI
  10.1038/srep12841
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08310, KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25430113, KAKENHI-PROJECT-25293081
[Journal Article] Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype.2015
- Author(s)
  Shigemura T, Shiohara M, Kato M, Furuta S, Kaneda K, Morishita K, Hasegawa H, Fujii M, Gorlach A, Koike K, Kamata T.
- Journal Title
  
  J Virol.
  
  Volume: 89 Issue: 17 Pages: 9080-9
- DOI
  10.1128/jvi.00983-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15087, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25293081, KAKENHI-PROJECT-15K21133
[Journal Article] Osteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia.2015
- Author(s)
  1.Maeda N, Ohashi T, Chagan-Yasutan, H, Hattori T, Takahashi Y, Harigae, H, Hasegawa H, Yamada Y, Fujii M, Maenaka K, and Uede T.
- Journal Title
  
  Retrovirology
  
  Volume: 12 Issue: 1 Pages: 99-99
- DOI
  10.1186/s12977-015-0225-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08490, KAKENHI-PROJECT-15H02384, KAKENHI-PROJECT-15H04704
[Journal Article] Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells2015
- Author(s)
  Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green PL, Fujii M.
- Journal Title
  
  Cance Science
  
  Volume: 106(4) Issue: 4 Pages: 461-465
- DOI
  10.1111/cas.12618
- NAID
  120006844098
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-15H04704, KAKENHI-PROJECT-25340027, KAKENHI-PROJECT-26242088
[Journal Article] Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax.2014
- Author(s)
  Higuchi M, Takahashi M, Tanaka Y, Fujii M.
- Journal Title
  
  Cancer Med.
  
  Volume: 3 Issue: 6 Pages: 1605-1614
- DOI
  10.1002/cam4.329
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461417, KAKENHI-PROJECT-26670222, KAKENHI-PROJECT-221S0001
[Journal Article] Stress granules inhibit apoptosis by reducing reactive oxygen species production.2013
- Author(s)
  Masahiko Takahashi
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33 Issue: 4 Pages: 815-829
- DOI
  10.1128/mcb.00763-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590537, KAKENHI-PROJECT-23591376, KAKENHI-PROJECT-23790498
[Journal Article] Stress granules inhibit apoptosis by reducing reactive oxygen species production2013
- Author(s)
  Takahashi M, Higuchi M, Matsuki H, Yoshita M, Ohsawa T, Oie M, Fujii M
- Journal Title
  
  Mol. Cell Biol
  
  Volume: 33(4) Pages: 815-829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T-cells by interacting with USP102013
- Author(s)
  Takahashi M, Higuchi M, Makokha GN, Matsuki H, Yoshita M, Tanaka Y, Fujii M
- Journal Title
  
  Blood
  
  Volume: 122(5) Pages: 715-725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T-cells by interacting with USP102013
- Author(s)
  Takahashi M, Higuchi M, Makokha GN, Matsuki H, Yoshita M, Tanaka Y, Fujii M.
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 5 Pages: 715-725
- DOI
  10.1182/blood-2013-03-493718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376, KAKENHI-PROJECT-221S0001
[Journal Article] Both G3BP1 and G3BP2 contribute to stress granule formation2013
- Author(s)
  Matsuki H, Takahashi M, Higuchi M, Makokha GN, Oie M, Fujii M
- Journal Title
  
  Genes Cells
  
  Volume: 18(2) Pages: 135-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells.2013
- Author(s)
  Michitaka Imai
- Journal Title
  
  Virus Genes
  
  Volume: 46 Issue: 1 Pages: 39-46
- DOI
  10.1007/s11262-012-0831-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590537, KAKENHI-PROJECT-23591376, KAKENHI-PROJECT-23659395, KAKENHI-PROJECT-23790436, KAKENHI-PROJECT-23790498, KAKENHI-PROJECT-221S0001
[Journal Article] Failure in activation of the NF-kB canonical pathway by human T-cell leukemia virus type 1 Tax in non-hematopoietic cell lines2013
- Author(s)
  Mizukoshi T, Komori H, Mizuguchi M, Abdelaziz H, Hara T, Higuchi M, Tanaka Y, Ohara Y, Funato N, Fujii M, Nakamura M
- Journal Title
  
  Virology
  
  Volume: 443(2) Pages: 226-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-12013
- Author(s)
  Makokha GN, Takahashi M, Higuchi M, Saito S, Tanaka Y, Fujii M
- Journal Title
  
  Cancer Science
  
  Volume: 104(3) Pages: 313-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Human T-cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI-12013
- Author(s)
  Grace Naswa Makokha
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 3 Pages: 313-320
- DOI
  10.1111/cas.12087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590537, KAKENHI-PROJECT-23591376, KAKENHI-PROJECT-23790498, KAKENHI-PROJECT-221S0001
[Journal Article] Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells2013
- Author(s)
  Imai M, Higuchi M, Kawamura H, Yoshita M, Takahashi M, Oie M, Matsuki H, Tanaka T, Aoyagi Y, Fujii M
- Journal Title
  
  Virus Genes 2013
  
  Volume: 46(1) Pages: 39-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth2012
- Author(s)
  Yoshita M, Higuchi M, Takahashi M, Oie M, Tanaka Y, Fujii M
- Journal Title
  
  Cancer Science
  
  Volume: 103(2) Pages: 69-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth2012
- Author(s)
  Yoshita M, Higuchi M, Takahashi M, Oie M, Tanaka Y, Fujii M. .
- Journal Title
  
  Cancer Science
  
  Volume: 103 Pages: 369-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591376
[Journal Article] Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-{kappa} B2009
- Author(s)
  Zhao T, Yasunaga JI, Satou Y, Nakao M, Takahashi M, Fujii M, Matsuoka M
- Journal Title
  
  Blood 113(12)
  
  Pages: 2755-2764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis2009
- Author(s)
  Higuchi M, Fujii M
- Journal Title
  
  Retrovirology 6
  
  Pages: 117-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20012014
[Journal Article] Knockdown of synapse-associated protein D1g1 reduces syncytium formation induced by human T-cell leukemia virus type 12008
- Author(s)
  Yoshida S, Higuchi M, Shoji T, Yoshita M, Ishioko K, Takahashi M, Oie M, Tanaka Y, Uchiyama M, Fujii M
- Journal Title
  
  Virus Genes 37(1)
  
  Pages: 9-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] Rearranged NF-kappa B2 gene in an adult T-cell leukemia cell line2008
- Author(s)
  Isogawa M, Higuchi M, Takahashi M, Oie M, Mori N, Tanaka Y, Aoyagi Y, Fujii M
- Journal Title
  
  Cancer Science 99(4)
  
  Pages: 792-798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] Human T-cell leukemia virus type 1 Tax induces an aberrant clustering of the tumor suppressor Scribble through the PDZ domain binding motif dependent and independent interaction2008
- Author(s)
  Okajima M, Takahashi M, Masaya Higuchi, Ohsawa T, Yoshida S, Yoshida Y, Oie M, Tanaka T, Gejyo F, Fujii M
- Journal Title
  
  Virus Genes 37(2)
  
  Pages: 231-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia2008
- Author(s)
  Nakayawa T, Hieshima K, Arao T, Jin Z, Nagakubo D, Shirakawa AK, Yamada Y, Fujii M, Oiso N, Kawada A, Nishio K, Yoshie O
- Journal Title
  
  Oncogene 27(23)
  
  Pages: 3221-3232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Journal Article] Cooperation of NF-kB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV) Taxl but not HTLV-2 Tax2 is crucial for interleukin-2 independent growth transformation of a T cell line2007
- Author(s)
  Higuchi M, Tsubata C, Kondo R, Yoshida S, Takahashi M, Oie M, Tanaka Y, Mahieux R, Matsuoka M, Fujii M
- Journal Title
  
  J Virol. 81(21)
  
  Pages: 11900-11907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591099
[Presentation] 神経変性疾患におけるユビキチン化蛋白質の凝集体形成の制御機構2022
- Author(s)
  藤井雅寛
- Organizer
  第62回新潟生化学懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24091
[Presentation] ストレス顆粒によるTDP-43 凝集体形成の制御機構2022
- Author(s)
  藤井雅寛
- Organizer
  第９５回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24091
[Presentation] USP10による蛋白質凝集体病の制御機構2022
- Author(s)
  藤井雅寛
- Organizer
  第２７回日本病態プロテアーゼ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24091
[Presentation] Pathogenic mechanisms in viral and non-viral neurodegenerative diseases2022
- Author(s)
  藤井雅寛
- Organizer
  第12回新潟大学脳研究所共同研究拠点国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10はドーパミンが誘導する活性酸素依存性の神経細胞死をNrf2の活性化によって抑制する,2021
- Author(s)
  山後淳也, 垣花太一, 葛城美徳, 高橋雅彦, アニシモフセルゲイ, 小松雅明, 藤井雅寛,
- Organizer
  第43回神経組織培養研究会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10はドーパミンが誘導する活性酸素依存性の神経細胞死をNrf2の活性化によって抑制する。2021
- Author(s)
  山後淳也, 垣花太一, 葛城美徳, 高橋雅彦, アニシモフセルゲイ, 藤井雅寛,
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] G3BP1およびUSP10はTDP-43との相互作用により異常な細胞質のTDP-43凝集を防ぐ2020
- Author(s)
  高橋雅彦、北浦弘樹、柿田明美、垣花太一、葛城美徳、小山哲秀、小野寺理、岩倉百合子、那波宏之、小松雅明、藤井雅寛
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10 inhibits dopamine-induced ROS-dependent apoptosis of neuronal cells through Nrf2/Keap1/p62 pathway2020
- Author(s)
  Junya Sango1, Taichi Kakihana1, Yoshinori Katsuragi, Masahiko Takahashi, Sergei Anisimov, Masahiro Fujii
- Organizer
  第43回　日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] ウイルス研究は面白い；ウイルス性神経疾患に基づいたパーキンソン病の発症機構の解析2020
- Author(s)
  藤井雅寛
- Organizer
  第34回日本バイオフィルム学会学術集会第57回日本細菌学会中部支部総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] Aberrant cytoplasmic aggregation of TDP-43 is prevented by interaction with G3BP1 and USP102020
- Author(s)
  藤井雅寛
- Organizer
  日本神経学会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] ウイルス性および非ウイルス性神経変性疾患の発症機構2020
- Author(s)
  藤井雅寛
- Organizer
  第42回神経組織培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10 is a critical factor in α-synuclein aggregation, aggresome and Lewy body formations but not GCI2019
- Author(s)
  Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Yuriko Iwakura, Hiroyuki Nawa, Masaya Higuchi, Masaaki Komatsu, Masahiro Fujii
- Organizer
  World Congress of Neurology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10 promotes Tau aggregation through stress granule formation in neuronal cells2019
- Author(s)
  Svetlana Piatnitskaia, Masahiko Takahashi, Hiroki Kitaura,　Yoshinori Katsuragi, Taichi Kakihana, Akiyoshi Kakita, Yuriko Iwakura, Hiroyuki Nawa, Takeshi Miura, Takeshi Ikeuchi, Toshifumi Hara, Masahiro Fujii
- Organizer
  第42回日本神経科学学会大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP102019
- Author(s)
  Anisimov, Masahiko Takahashi, Yoshinori Katsuragi, Taichi Kakihana, Hiroki Kitaura, Akiyoshi Kakita, Masahiro Fujii
- Organizer
  第42回日本神経科学学会大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10 promotes aggresome formation to induce α-synuclein aggregation and Lewy body but not GCI2019
- Author(s)
  Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Yuriko Iwakura, Hiroyuki Nawa, Masaya Higuchi, Masaaki Komatsu, Masahiro Fujii
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] USP10 is a critical factor for aggresome formation to induce α-synuclein aggregation and Lewy body but not GCI2019
- Author(s)
  Masahiko Takahashi, Hiroki Kitaura, Akiyoshi Kakita, Taichi Kakihana, Yoshinori Katsuragi, Yuriko Iwakura, Hiroyuki Nawa, Masaya Higuchi, Masaaki Komatsu, Masahiro Fujii
- Organizer
  第42回日本神経科学学会大会
- Data Source
  KAKENHI-PROJECT-19H03432
[Presentation] Role of ROS in pathogenesis of HTLV-1-associated diseases2018
- Author(s)
  藤井雅寛
- Organizer
  Frontiers in Retrovirology Conference 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15502
[Presentation] Role of ROS in pathogenesis of HTLV-1-associated diseases.2018
- Author(s)
  藤井雅寛
- Organizer
  Frontiers in Retrovirology Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09822
[Presentation] Signal transduction of reactive oxygen species in HAM and ATL2017
- Author(s)
  藤井雅寛、高橋雅彦、樋口雅也
- Organizer
  日本HTLV-1学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15502
[Presentation] ストレス顆粒とオートファジーによる酸化ストレスの制御機構2017
- Author(s)
  藤井雅寛, 原敏文、樋口雅也、高橋雅彦
- Organizer
  日本抗加齢医学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15502
[Presentation] Stress granules and autophagy control degradation of neuropathogenic RNA-binding proteins2017
- Author(s)
  Masahiro Fujii, Toshifumi Hara, Masaya Higuchi, Osamu Onodera, Masahiko Takahashi
- Organizer
  日本神経科学学会
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] ストレス顆粒とオートファジーによる酸化ストレスの制御機構2017
- Author(s)
  藤井雅寛, 原敏文、樋口雅也、高橋雅彦
- Organizer
  日本抗加齢医学会
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] Stress granules and autophagy control degradation of neuropathogenic RNA-binding proteins2017
- Author(s)
  Masahiro Fujii, Toshifumi Hara, Masaya Higuchi, Osamu Onodera, Masahiko Takahashi
- Organizer
  日本神経科学学会
- Data Source
  KAKENHI-PROJECT-16K15502
[Presentation] Signal transduction of reactive oxygen species in HAM and ATL2017
- Author(s)
  藤井雅寛、高橋雅彦、樋口雅也
- Organizer
  日本HTLV-1学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] 脱ユビキチン化酵素USP10はHematopoietic stem cellの恒常性維持に必須である2016
- Author(s)
  川村宏樹、樋口雅也、藤井雅寛
- Organizer
  日本生体防御学会
- Place of Presentation
  九州大学(福岡県福岡市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] 脱ユビキチン化酵素USP10はHematopoietic stem cellの恒常性維持に必須である2016
- Author(s)
  川村宏樹、樋口雅也、藤井雅寛
- Organizer
  第27回日本生体防御学会学術総会
- Place of Presentation
  九州大学（福岡県福岡市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16K15502
[Presentation] HTLV-1 Tax oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB2015
- Author(s)
  Fujii M、Motai Y, Takachi T, Higuchi M, Hara T, Takahashi M
- Organizer
  第63回日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26670222
[Presentation] Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATLL development2015
- Author(s)
  Ichikawa T, Nakahata S, Fujii M, Iha H, Morishita K.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] HTLV-1のTax1はHTLV-2のTax2とは異なる細胞遺伝子の発現をNF-kB2を介して誘導する2015
- Author(s)
  藤井雅寛、罇陽介、原敏文、高橋雅彦
- Organizer
  HTLV-1学会
- Place of Presentation
  東京大学医科学研究所(東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-26670222
[Presentation] HTLV-1 Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB2015
- Author(s)
  Masahiro Fujii, Yosuke Motai, Masaya Higuchi, Toshifumi Hara, Masahiko Takahashi
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場(福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] Ubiquitin Specific Protease 10 is essential for hematopoietic stem cell maintenance2015
- Author(s)
  Masaya Higuchi, Hiroki Kawamura, Toshifumi Hara, Masahiko Takahashi, Masahiro Fujii
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  ホテル日航金沢（石川県金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] HTLV-1のTax1はHTLV-2のTax2とは異なる細胞遺伝子の発現をNF-kB2を介して誘導する2015
- Author(s)
  藤井雅寛、罇陽介、原俊文、高橋雅彦
- Organizer
  第2回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-15H04704
[Presentation] 新規RasGAP蛋白RASAL3の生体内機能解析2014
- Author(s)
  齋藤卓、樋口雅也、藤井雅寛
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26670222
[Presentation] HTLV-1 Taxによる細胞周期依存的な遺伝子発現の解析2014
- Author(s)
  水口真理子、樋口雅也、藤井雅寛、中村正孝
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26670222
[Presentation] HTLV-1のTax蛋白はUSP10を介してROS産生とROS依存性アポトーシスを誘導する2013
- Author(s)
  高橋雅彦、樋口雅也、藤井雅寛
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 TaxはUSP10と結合することによりT細胞におけるROS産生とアポトーシス誘導を活性化する2013
- Author(s)
  高橋雅彦、樋口雅也、藤井雅寛
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 TaxによるNF-kBを介した増殖メカニズムの解析2013
- Author(s)
  水口真理子、樋口雅也、藤井雅寛、中村正孝
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Naswa Makokha Grace PDZ蛋白MAGI-1の不活化はHTLV-1のTaxによるT細胞のトランスフォーメーションに関与する2013
- Author(s)
  藤井雅寛、高橋雅彦、樋口雅也
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Stress granules inhibit apoptosis by reducing ROS production, but this phenomenon is nullified by HTLV-1 Tax2013
- Author(s)
  Takahashi M, Higuchi M, Fujii M
- Organizer
  16^<th> International Conference on Human Retrovirology HTLV and Related Viruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] MAGI-1の不活化はHTLV-1 TaxによるT細胞のトランスフォーメーションに関与する2013
- Author(s)
  Fujii M, Makokha GN, Higuchi M, Takahashi M
- Organizer
  第6回HTLV-1研究会
- Place of Presentation
  東京大学医科学研究所、東京
- Year and Date
  2013-08-25
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Both G3BP1 and G3BP2 contribute to stress granule formation2012
- Author(s)
  Matsuki H, Takahashi M, Higuchi M, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] USP10は亜ヒ酸によるHTLV-1感染細胞のアポトーシス感受性に関与する2012
- Author(s)
  高橋雅彦,樋口雅也、藤井雅寛
- Organizer
  第5回HTLV-1研究会
- Place of Presentation
  東京大学医科学研究所、東京
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Downregulation of the multi-PDZ domain protein MAGI-1 is associated with transformation of Tcells by HTLV-1 Tax12012
- Author(s)
  Makokha GN, Takahashi M, Higuchi M, Saito S, Tanaka Y, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育分化会館, 北海道
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax induces cell death through the NF-kB pathway2012
- Author(s)
  Mizuguchi M, Higuchi M, Fujii M, Nakamura M.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Stress granules inhibit apoptosis by ROS production, and this is nullified by HTLV-1 Tax12012
- Author(s)
  Takahashi M, Higuchi M, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Downregulation of the multi-PDZ domain protein MAGI-1 is associated with transformation of T-cells by HTLV-1 Tax12012
- Author(s)
  Makokha GN, Takahashi M, Higuchi M, Saito S, Tanaka Y, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells2012
- Author(s)
  Higuchi M, Yoshita M, Takahashi M, , Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells2012
- Author(s)
  Higuchi M, Takahashi M, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育分化会館, 北海道
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax induces cell death through the NF-kB pathway2012
- Author(s)
  Mizuguchi M, Higuchi M, Fujii M, Nakamura M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育分化会館, 北海道
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Both G3BP1 and G3BP2 contribute to stress granule formation2012
- Author(s)
  Matsuki H, Takahashi M, Higuchi M, Fujii M
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育分化会館, 北海道
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] ストレス顆粒はROS産生を抑制することによりアポトーシスを阻害するが、これをHTLV-1のTax1は解除する2012
- Author(s)
  高橋雅彦,樋口雅也,藤井雅寛
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市教育分化会館, 北海道
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] USP10は亜ヒ酸によるHTLV-1感染細胞のアポトーシス感受性に関与する2012
- Author(s)
  高橋雅彦、樋口雅也、藤井雅寛
- Organizer
  第5回HTLV-1研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] A novel HTLV-1 Tax-binding protein USP10 inhibits an oxidative stress-induced ROS production and apoptosis2011
- Author(s)
  Fujii M、Takahashi M, Higuchi M
- Organizer
  第15回国際ウイルス学会
- Place of Presentation
  札幌コンベンションセンター, 札幌
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Epidemiological disease association of human parechovirus in Niigata, Japan2011
- Author(s)
  Watanabe K, Fujii M
- Organizer
  第15回国際ウイルス学会
- Place of Presentation
  札幌コンベンションセンター, 札幌
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-2のTax2によるヒトＴ細胞の不死化活性はHTLV-1のTax1よりも強い2011
- Author(s)
  藤井雅寛、今井径卓、樋口雅也
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京大学弥生講堂（東京都）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Activation of mTOR by HTLV-1 Tax is crucial for IL-2 independent growth transformation of a mouse T-cell line2011
- Author(s)
  由田真奈美、樋口雅也、藤井雅寛
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax induces both cell growth and death2011
- Author(s)
  水口真理子、樋口雅也、藤井雅寛、中村正孝
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] A novel HTLV-1 Tax-binding protein USP10 inhibits an oxidative stress-induced ROS production and apoptosis2011
- Author(s)
  Masahiro Fujii, Masahiko Takahashi, Masaya Higuchi
- Organizer
  第１５回国際ウイルス学会
- Place of Presentation
  札幌コンベンションセンター(札幌）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax does not activate the NF-kB canonical pathway in REF52 cells2011
- Author(s)
  水越てるみ、樋口雅也、藤井雅寛、中村正孝
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Ditinct activities of HTLV-1 Tax1 from HTLV-2 Tax2 play key roles in apthogenesis2011
- Author(s)
  Masahiro Fujii
- Organizer
  Frontiers of Retrovirology(招待講演)
- Place of Presentation
  Movenpick Hotel(Amsterdam)
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-2のTax2によるヒトT細胞の不死化活性はHTLV-1のTax1よりも強い2011
- Author(s)
  藤井雅寛、今井径卓、樋口雅也
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京大学弥生講堂、東京
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation2011
- Author(s)
  Masaya Higuchi, Masahiro Fujii
- Organizer
  15th international conference of human retrovirology HTLV and related viruses
- Place of Presentation
  Leuven University(Belgium)
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax1とHTLV-2 Tax2の違いが病原性に寄与する2011
- Author(s)
  樋口雅也,高橋雅彦,藤井雅寛
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax induces both cell growth and death2011
- Author(s)
  水口真理子、樋口雅也、　藤井雅寛、　中村正孝
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Distinct activities of HTLV-1 Tax1 from HTLV-2 Tax2 play key roles in pathogenesis2011
- Author(s)
  Fujii M
- Organizer
  医歯学系Frontiers of Retrovirology
- Place of Presentation
  Movenpick Hotel、Amsterdam、オランダ
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Distinct functions of HTLV-1 Tax1 and HTLV-2 Tax2 contribute to the pathogenesis2011
- Author(s)
  樋口雅也、高橋雅彦、藤井雅寛
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax does not activate the NF-kB canonical pathway in REF52 cells2011
- Author(s)
  水越てるみ、樋口雅也、　藤井雅寛、　中村正孝
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Epidemiologynad disease assocaition of human parechovirus in Niigata, Japan2011
- Author(s)
  Kanako Watanabe, Masahiro Fujii
- Organizer
  第１５回国際ウイルス学会
- Place of Presentation
  札幌コンベンションセンター(札幌）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation2011
- Author(s)
  Higuchi M, Fujii M
- Organizer
  15^<th> International Conference on Human Retrovirology : HTLV and Related Viruses
- Place of Presentation
  Leuven, Belgium
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Activation of mTOR by HTLV-1 Tax is crucial for IL-2 independent growth transformation of a mouse T-cell line2011
- Author(s)
  由田真奈美、樋口雅也、　藤井雅寛、
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Inhibition of cytoplasmic mRNA stress granule formation by HTLV-12009
- Author(s)
  Fujii M, et al
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] HTLV-1によるストレス応答の抑制2009
- Author(s)
  高橋雅彦、樋口雅也、藤井雅寛
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  都市センターホテル(東京).
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] アポトーシス促進因子Bimの発現抑制がHTLV-1 Tax1によるトランスフォメーションに関与する2009
- Author(s)
  藤井雅寛、高橋雅彦、樋口雅也
- Organizer
  第2回HTLV-1研究会
- Place of Presentation
  東京大学医科学研究所(東京)
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] HTLV-1 Tax1によるアポトーシス促進因子Bimの発現抑制2009
- Author(s)
  樋口雅也、高橋雅彦、藤井雅寛
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  都市センターホテル(東京)
- Year and Date
  2009-10-25
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] HTLV-1 Tax1とHTLV-2 Tax2によるIL-2非依存性細胞増殖誘導能の違い2008
- Author(s)
  藤井雅寛
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] Activation of PI3k/Akt substitutes a function of PDZ domain bindina motif of HTLV-1 Tax in its T-cell transformation2008
- Author(s)
  藤井雅寛
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20012014
[Presentation] Activation of PI3k/Akt substitues a function of PDZ domain binding motif of HTLV-1 Tax in its T-cell transformation2008
- Author(s)
  藤井雅寛
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591099
[Presentation] HTLV-1Taxl と HTLV-2Tax2によるIL-2非依存性細胞増殖誘導能の違い2008
- Author(s)
  藤井雅寛
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19591099
[Presentation] Distinct T-cell transformation mechanisms of HTLV-1 Tax1 and HTLV-2 Tax22007
- Author(s)
  藤井雅寛
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19591099
[Presentation] Distinct T-cell transformation mechanisms of HTLV-1 Taxl and HTLV-2 Taxl22007
- Author(s)
  藤井雅寛
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19591099
[Presentation] Distinct T-cell transformation mechanisms of HTLV-1 Tax1 and HTLV-2 Tax22007
- Author(s)
  藤井雅寛
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18012016
[Presentation] PDZ蛋白MAGI-1の不活化はHTLV-1のTaxによるＴ細胞のトランスフォーメーションに関与する
- Author(s)
  藤井雅寛、高橋雅彦、樋口雅也、Makokha Grace Naswa
- Organizer
  日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 TaxによるNF-kBを介した増殖メカニズムの解析
- Author(s)
  水口真理子、樋口雅也、藤井雅寛、中村正孝
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] 成人Ｔ細胞白血病ウイルス癌蛋白TaxとHBZはBCL11B遺伝子発現を抑制する
- Author(s)
  高地貴行、由田真奈美、高橋雅彦、樋口雅也、大家正泰、小幡美貴、三嶋行雄、木南凌、松岡雅雄、藤井雅寛
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1のTax蛋白はUSP10を介してROS産生とROS依存性アポトーシス誘導を誘導する
- Author(s)
  高橋雅彦、樋口雅也,藤井雅寛
- Organizer
  日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] MAGI-1の不活化はHTLV-1のTaxによるＴ細胞のトランスフォーメーションに関与する
- Author(s)
  藤井雅寛、Makokha Grace Naswa, 樋口雅也、高橋雅彦
- Organizer
  HTLV-1研究会
- Place of Presentation
  東京大学医科学研究所（東京）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] HTLV-1 TaxはUSP10と結合することによりＴ細胞におけるROS産生とアポトーシス誘導を活性化する
- Author(s)
  高橋雅彦、樋口雅也、藤井雅寛
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] Stress granules inhibit apoptosis by reducing ROS production, but this phenomenon is nullified by HTLV-1 Tax
- Author(s)
  Masahiko Takahashi, Masaya Higuchi, Masahiro Fujii
- Organizer
  International conference on humna retrovirology: HTLV and related viruses
- Place of Presentation
  Holliday in Motreal Midtown (モントリオール、カナダ）)
- Data Source
  KAKENHI-PROJECT-23591376
[Presentation] USP10はボルテゾミブによるATL細胞のアポトーシスを抑制する
- Author(s)
  藤井雅寛、髙橋真奈美、原敏文、樋口雅也、髙橋雅彦
- Organizer
  第２回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所　講堂
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-26670222

1. 清木元治 (10154634)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 高橋雅彦 (80377192)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
3. SAITO Kosuke (30460356)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 長谷川成人 (10251232)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 柿田明美 (80281012)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. SAITO Reiko (30345524)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HASEGAWA Go (90251800)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SAITOH Akihiko (30531389)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 垣花太一 (60746907)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. HIGUCHI Masaya

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
11. NAITO Makoto (30045786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OOIE Masayasu (70108017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OOHASHI Riuko (20447600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITO Takehiko (00263393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHOBUGAWA Yugo (30621198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Komatsu Masaaki (90356254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 佐藤博 (00115239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 田中淳之 (60019875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 菅村和夫 (20117360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渡邊俊樹 (30182934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 内山卓 (80151900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 藤澤順一 (40181341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 赤城剛 (90184077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 吉木敬 (60220612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 小野寺理 (20303167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 渡邉香奈子 (80626094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. HIBINO Akinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KONDO Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ODAGIRI Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. SUZUKI Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. TAMURA Tsutomu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. Dapat Clyde

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. Yadanar Kyaw

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Yi Yi Myint

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. Nay Lin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. Htay Htay Tin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. Khin Yi OO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Latt Latt Kyaw

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. Rohaizat Mohd Hassan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. Shamsul Azhar Shah

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. Nguyen Le Khanh Hang

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. Nguyen Phuong Anh

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. Le Quynh Mai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. Zaraket Hassan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. Dbaibo Ghassan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. Kageyama Shun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. Hara Toshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
48. Koyama Akihide

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. Katsuragi Yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. NAKAMURA Masataka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. SUGIURA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. MAEDA Naoyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 船戸紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 増子正義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 斎藤孔良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 市川朝永

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
57. アニシモフセルゲイ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 神吉智丈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 森下和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 大橋貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJII Masahiro 藤井 雅寛

藤井 雅見 フジイ マサヒロ

藤井 雅寛 フジイ マサヒロ

Research Projects

Research Products

Co-Researchers

アルツハイマー病の進行期におけるUSP10を介した神経細胞死の制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a mouse model of human parechovirus A3 infection and elucidation of the mechanism of severe infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

神経病原性蛋白質オリゴマーの神経毒性を抑制する分子メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of inactivation of neuropathogenic protein toxicity by aggresomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation mechanism of Ras signal by novel RasGAP specific to blood cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ROS production regulation by stress granulePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Crosstalk between stress granules and autophagy in protein degradationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of antivirus innate immunity by stress granulesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influenza virus transmission, evolution and appearance of drug resistant viruses in Asia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of arsenite therapy against adult T-cell leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influenza surveillance in Myanmar: investigations on emergence of drug resistant strains and clinical pictures of H1N1pdm09

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

サイトカイン非依存性細胞増殖のHTLV-1発がんにおける意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Activation of NF-kB2 in adult T-cell leukemiaPrincipal Investigator

Principal Investigator

FUJII Masahiro 藤井雅寛

藤井雅見フジイマサヒロ

藤井雅寛フジイマサヒロ