Mihara Hisakazu 三原久和

… Alternative Names

MIHARA Hisakazu 三原久和

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Researcher Number	30183966
Other IDs
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Affiliation (based on the past Project Information) *help	2019 – 2023: 東京工業大学, 生命理工学院, 教授 2015 – 2017: 東京工業大学, 生命理工学院, 教授 2011 – 2013: 東京工業大学, 生命理工学研究科, 教授 2010 – 2011: 東京工業大学, 大学院・生命理工学研究科, 教授 2007 – 2008: Tokyo Institute of Technology, 大学院・生命理工学研究科, 教授 … More 2005 – 2008: 東京工業大学, 生命理工学研究科, 教授 2005 – 2006: 東京工業大学, 大学院生命理工学研究科, 教授 2005: 東京工業大学, 大学院・生命理工学研究科, 教授 1999 – 2004: Tokyo Institute of Technology, Graduate School of Bioscience and Biotechnology, Associate professor, 大学院・生命理工学研究科, 助教授 2001 – 2003: 東京工業大学, 生命理工学部, 助教授 1995 – 1999: 東京工業大学, 生命理工学部, 助教授 1993: 長崎大学, 工学部, 助教授 1989 – 1992: 九州工業大学, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Science and Engineering / Nanomaterials/Nanobioscience / Medium-sized Section 37:Biomolecular chemistry and related fields / Biofunction/Bioprocess / 生物・生体工学 / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biomolecular chemistry / Bioorganic chemistry / Inorganic chemistry / Science and Engineering / Biological Sciences / Living organism molecular science / 高分子合成 … More Except Principal Investigator … More 物理学一般 / 工業物理化学 / 高分子合成 / 高分子合成 / Science and Engineering Less
Keywords	Principal Investigator ペプチド / βシート / アミロイド / タンパク質 / 立体構造 / α-ヘリックス / バイオチップ / ポルフィリン / ライブラリ / プロテインチップ … More / マイクロアレイ / peptide / αヘリックス / 合成 / 超構造 / ナノ粒子 / リガンド / 蛍光 / protein / CDR / alpha-helix / バイオナノ / アルツハイマー病 / チップ / 自己組織化 / β-シート / 超分子 / 次世代医薬品 / クラスター効果 / ファージ提示法 / タンパク質相互作用 / 薬剤複合体 / ファージ提示 / イメージング / ガン細胞 / 細胞相互作用 / 生体分子科学 / loop / beta-sheet / microarray / protein chip / ループ / 2D structure / library / molecular recognition / antibody / 計算機化学 / 分子認識 / 抗体 / Fe-porphyrin / metal ion / artificial metalloprotein / de novo design / 設計 / 分子複合体 / 鉄-ポルフィリン / 金属イオン / デノボ設計 / 人工金属タンパク質 / ポリペプチド / 細胞 / ナノファイバー / 融合マテリアル / ナノフファイバー / 非標識 / 反射法 / 金基板 / 捕捉剤 / 化合物ライブラリ / ペプチドアレイ / ナノバイオ / アルツハイマー / 構造転移 / 線維形成 / RNA / 立体構造転移 / ミニ抗体 / 分子集合体 / チオールサブチリシン / 人工リガーゼ / 酵素触媒 / 人工ヘムタンパク質 / β-構造 / ピレン / 構造評価法 / 超2次構造 / モデルタンパク質 / 電子移動 / 電気化学 / ポリペプチド合成 / ポリペプチド設計 / 酸化還元機能 / フラビン / 人工タンパク質 … More Except Principal Investigator 立体構造構築 / fluorescence / cyclodextrin / ダンシル / 蛍光 / シクロデキストリン / 分子認識 / エネルギー移動 / Molecular structure / Electronic structure / Synthesis and AFM observation / D.L alternating amino acids rings / Ab initio molecular orbitals theory / Mathematical molecular desigining / Protein nanoring / Protein nanotube / 分子構造と電子構造 / 骨格構造の数理 / ワイドバンドギャップ半導体 / AFM観察 / Fmoc固相合成 / 環状ペプチド / 第一原理電子論 / 蛋白質ナノチューブ / ペプチドナノリング / 高分子合成 / 電子状態 / 生体高分子 / 分子構造 / 電子構造 / L体アミノ酸5残基リング / D, L交互アミノ酸リング / 非経験的分子軌道理論 / 数理構造解析 / タンパク質ナノリング / タンパク質ナノチューブ / sensor / host-guest / inclusion complex / dansyl / シクロファン / (7)ホスト・ゲスト / (6)分子包接 / (5)光ファイバー / (4)ガラス / (3)β-シクロデキストリン / (2)蛍光 / (1)ダンシル / ホスト・ゲスト / 分子包接 / センサー / β-シンクロデキストリン / ant nn / energy transfer / naphthalene / rotaxane / polymer / ホスドゲスト / ポリロタクサン / α-シクロテキストリン / ロタクカン / ナフタレン / 高分子 / 超分子 / ロタクサン / Growth Hormone Releasing Factor / Biologically Active peptide / Trypsin / Serratia Protease / Protease Catalysis / Peptide Synthesis / ヒト成長ホルモン放出因子 / セラチア56Kプロテア-ゼ / 生理活性ポリペプチド / 成長ホルモン放出因子 / 生理活性ペプチド / トリプシン / セラチアプロテア-ゼ / プロテア-ゼ触媒 / ペプチド合成 / 量子ドット / 機能性タンパク質 / 化学センサー / 化合物ライブラリー / ペプチドアレイ / 分子クラウディング / DNA構造変化 / バイオセンサー / ピレン・インドール・ダンシル / 人工アミノ酸 / 4α-ヘリックスバンドル構造 / 人工タンパク質 / 機能性ポリペプチド / ビオロ-ゲン / アントラキノン / ルテニウム・トリスビピリジル錯体 / 光誘起電子移動素子 / αーヘリックス / 機能性ポリペプチドの設計合成 / ビピリジルーペプチド / 二分子膜埋設 / ピケットフェンス型ポルフィリン / ポリペプチドの設計合成 Less

Target-directed phage display method and functional nanoparticles for next generation peptide medicinesPrincipal Investigator
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tokyo Institute of Technology
Analysis of biomolecular dynamics on the cell surface using multifunctional nanoparticle probesPrincipal Investigator
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Tokyo Institute of Technology
Construction of a Peptide Drug Discovery Platform Using Chemically Modified Peptide Phage LibrariesPrincipal Investigator
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tokyo Institute of Technology
Development of various functional peptides for biochips analyzing cancer cellsPrincipal Investigator
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo Institute of Technology
Construction of a cell-analyzing biochipPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo Institute of Technology
自己組織化ペプチドを用いるナノファイバーの構築と融合マテリアル展開Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Construction of functional peptide ligands toward peptide biochipsPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo Institute of Technology
Construction of label-free biochips using anomalous reflection of goldPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Tokyo Institute of Technology
ペプチドを用いるタンパク質アミロイドの形成機構解析と制御Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Construction of Protein detection Chips Using Peptide ArraysPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Tokyo Institute of Technology
Development of Novel Chemical Tools, Materials and Devices for Precise and Digital Analysis of Single Cell
- Principal Investigator
  
  HAMACHI Itaru
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
アルツハイマー病アミロイド高感度検出のためのチップテクノロジー創製Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Tokyo Institute of Technology
ゲノム情報を利用する新規プロテインチップの開発Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
ペプチドを用いるタンパク質アミロイドの形成機構解析と制御Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
ナノチップテクノロジーを指向したペプチドマイクロアレイの構築Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo Institute of Technology
疎水性相互作用を利用したペプチドアミロイド組織化構造体の動的制御Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Construction of a protein detection system for development of a protein chipPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY
疎水性相互作用を利用したペプチドアミロイド組織化構造体の動的制御Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
First-principles theory of the protein nanotubes
- Principal Investigator
  
  TAKEDA Kyozaburo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  物理学一般
- Research Institution
  Waseda University
Construction of Functional Peptide Libraries based on Antibody CDRPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo Institute of Technology
蛋白質のα-β構造転移とアミロイド形成のモデル化Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Institute of Technology
Construction and Function of Supramolecular polvmers
- Principal Investigator
  
  UENO Akihiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  高分子合成
- Research Institution
  Tokyo Institute of Technology
Construction of Molecule Sensing Systems and Evaluation of Their Abilities
- Principal Investigator
  
  UENO Akihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  工業物理化学
- Research Institution
  Tokyo Institute of Technology
機能性原子団を複合化したポリペプチド系超構造の構築と新機能創成Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
Construction of Protein 2D-/3D Structures by Complexation with Metal Ion or Fe-PorphyrinPrincipal Investigator
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Inorganic chemistry
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY
ポリペプチド高次構造の人工組織化による機能性原子団-ペプチド系超構造の構築Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
タンパク質合成用高効率リガーゼシステムの開発Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Tokyo Institute of Technology
ポリペプチド高次構造の人工組織化によるポルフィリン-ペプチド系超構造の構築Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
設計モデル蛋白質の化学合成と立体構造形成機構の解明Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
フラビンを機能団として有する酸化還元機能性人工タンパク質の設計合成Principal Investigator
- Principal Investigator
  
  三原久和
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  高分子合成
- Research Institution
  Nagasaki University
光電子機能を有するポリペプチド性情報変換分子モジュールの組立と機能性御
- Principal Investigator
  
  西野憲和
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu Institute of Technology
光電子機能を有するポリペプチド性情報変換分子モデュ-ルの組立と機能制御
- Principal Investigator
  
  西野憲和
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu Institute of Technology
光電子機能を有するポリペプチド性情報変換分子モデュ-ルの組立と機能制御
- Principal Investigator
  
  NISHINO Norikazu
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu Institute of Technology
Synthesis of Biologically Active Polypeptides Mediated by Highly Specific Serratia 56K Protease
- Principal Investigator
  
  NISHINO Norikazu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  高分子合成
- Research Institution
  Kyushu Institute of Technology

[Book] 医療・診断をささえるペプチド科学－再生医療・DDS・診断への応用2017
- Author(s)
  堤浩、三原久和
- Total Pages
  315
- Publisher
  シーエムシー出版
- ISBN
  9784781312675
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017
- Author(s)
  堤浩、三原久和
- Total Pages
  557
- Publisher
  技術情報協会
- ISBN
  9784861046872
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] Peptide Microarrays-Method and Protocols2016
- Author(s)
  Kenji Usui, Kinya Tomizaki, Hisakazu Mihara
- Total Pages
  296
- Publisher
  Springer
- ISBN
  9781493930371
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] バイオチップの基礎と応用－原理から最新の研究・開発動向まで－2015
- Author(s)
  臼井健二、堤　浩、三原久和
- Total Pages
  275
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] デザインペプチドを用いたプロテインアレイと細胞アレイ化学フロンティア22,生命現象を理解する分子ツール2010
- Author(s)
  臼井健二,富崎欣也,三原久和
- Total Pages
  181
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-22360341
[Book] Designed Peptide Chip : Protein Fingerprinting Technology with a Dry Peptide Array and Statistical Data Mining, Peptide Microarrays2009
- Author(s)
  K. Usui, K.-Y. Tomizaki, H. Mihara A
- Publisher
  Methods in Molecular Biology, Humana Press
- Data Source
  KAKENHI-PROJECT-18310087
[Book] Array Based Techniques Wiley Encyclopedia of Chemical Biology2009
- Author(s)
  K.-Y. Tomizaki, K. Usui, H. Mihara Proteins(Ed. Begley, T. P.)
- Publisher
  John Wiley & Sons, Inc
- Data Source
  KAKENHI-PROJECT-18310087
[Book] バイオ研究のフロンティア2、酵素・タンパク質をはかる・とらえる・利用する2009
- Author(s)
  岡畑恵雄・三原久和
- Total Pages
  188
- Publisher
  工学図書
- Data Source
  KAKENHI-PROJECT-17066005
[Book] バイオ研究のフロンティア2、酵素・タンパク質をはかる・とらえる・利用する2009
- Author(s)
  岡畑恵雄、三原久和
- Total Pages
  188
- Publisher
  工学図書
- Data Source
  KAKENHI-PROJECT-18310087
[Book] とことんやさしいタンパク質の本、プロテインチップでタンパク質を検出2007
- Author(s)
  三原久和、高橋剛、富崎欣也
- Publisher
  日本工業新聞社
- Data Source
  KAKENHI-PROJECT-18310087
[Book] 「新しいDNAチップの科学と応用」プロテインチップの開発2007
- Author(s)
  富崎欣也、三原久和
- Total Pages
  13
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-17066005
[Book] ナノバイオ計測の実際2007
- Author(s)
  三原久和、小畠英理、馬場嘉信
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-17066005
[Book] 新しいDNAチップの科学と応用(関根光雄編)2007
- Author(s)
  富崎欣也、三原久和
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-18310087
[Book] ナノバイオ計測の実際2007
- Author(s)
  三原久和、小畠英理、馬場嘉信
- Total Pages
  224
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-18310087
[Book] 「マイクロアレイ・バイオチップの最新技術」ペプチドチップ2007
- Author(s)
  富崎欣也、三原久和
- Total Pages
  13
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-17066005
[Book] とことんやさしいタンパク質の本2007
- Author(s)
  三原久和、高橋剛、富崎欣也
- Total Pages
  8
- Publisher
  日本工業新聞社
- Data Source
  KAKENHI-PROJECT-17066005
[Book] ペプチドチップマイクロアレイ・バイオチップの最新技術2007
- Author(s)
  富崎欣也、三原久和
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-18310087
[Book] 一細胞定量解析の最前線-ライフサーベイヤ構築に向けて- 第2章生体シグナル解析用分子材料群の創製、4.ペプチドチップテクノロジーによるシグナル解析2006
- Author(s)
  富崎欣也, 三原久和
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-17066005
[Book] 図解高分子新素材のすべて,ペプチド工学2005
- Author(s)
  三原久和
- Publisher
  工業調査会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides2021
- Author(s)
  Hashimoto Masahiro、Miki Takayuki、Chang Iou Ven、Tsutsumi Hiroshi、Mihara Hisakazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 37 Pages: 127835-127835
- DOI
  10.1016/j.bmcl.2021.127835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15696, KAKENHI-PROJECT-19H02838
[Journal Article] hDM2 protein-binding peptides screened from stapled α-helical peptide phage display libraries with different types of staple linkers2020
- Author(s)
  Anananuchatkul Teerapat、Tsutsumi Hiroshi、Miki Takayuki、Mihara Hisakazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 23 Pages: 127605-127605
- DOI
  10.1016/j.bmcl.2020.127605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02838
[Journal Article] Construction of a Stapled α-Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands2020
- Author(s)
  Anananuchatkul Teerapat、Chang Iou Ven、Miki Takayuki、Tsutsumi Hiroshi、Mihara Hisakazu
- Journal Title
  
  ACS Omega
  
  Volume: 5 Issue: 11 Pages: 5666-5674
- DOI
  10.1021/acsomega.9b03461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05351, KAKENHI-PROJECT-19K22249, KAKENHI-PROJECT-19K15696, KAKENHI-PROJECT-19H02838
[Journal Article] Gold Nanoparticles Conjugated with Glycopeptides for Lectin Detection and Imaging on Cell Surface2018
- Author(s)
  Hiroshi Tsutsumi, Tomoko Shirai, Hiroyuki Ohkusa, Hisakazu Mihara
- Journal Title
  
  Protein Peptide Letter
  
  Volume: 25 Issue: 1 Pages: 84-89
- DOI
  10.2174/0929866525666171218124434
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] Screening for Concanavalin A Binders from a Mannose-modified alpha-Helix Peptide Phage Library2017
- Author(s)
  Iou Ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Journal Title
  
  Molecular BioSystems
  
  Volume: 13 Issue: 11 Pages: 2222-2225
- DOI
  10.1039/c7mb00495h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Designed β-Loop Peptide Library Displayed on Phage2015
- Author(s)
  Hiroshi Tsutsumi, Kazuhiro Nakano, Hisakazu Mihara
- Journal Title
  
  Molecular BioSystems
  
  Volume: 11 Issue: 10 Pages: 2713-2716
- DOI
  10.1039/c5mb00316d
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] A Monosaccharide-modified Peptide Phage Library for Screening of Ligands to Carbohydrate-binding Proteins2013
- Author(s)
  K. Arai, H. Tsutsumi, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Pages: 4940-4943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] Cell Penetration and Cell-selective Drug Delivery Using α-Helix Peptides Conjugated with Gold Nanoparticles2013
- Author(s)
  H.J. Park, H. Tsutsumi, H. Mihara
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 20 Pages: 4872-4879
- DOI
  10.1016/j.biomaterials.2013.03.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] A Peptide Release System using a Photo-cleavable Linker in a Cell Array Format for Cell-toxicity Analysis2013
- Author(s)
  Takashi Kakiyama, Kenji Usui, Kinya Tomizaki, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara
- Journal Title
  
  Polymer J.
  
  Volume: 45 Issue: 5 Pages: 535-539
- DOI
  10.1038/pj.2013.20
- NAID
  10031166681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] Systematic Screening of the Cellular Uptake of Designed alpha-Helix Peptides Bioorg2013
- Author(s)
  K. Usui, T. Kikuchi, M. Mie, E. Kobatake, H. Mihara
- Journal Title
  
  Med. Chem.
  
  Volume: 21 Pages: 2560-2567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] A Novel Array Format for Monitoring Cellular Uptake Using a Photo-Cleavable Linker for Peptide Release2013
- Author(s)
  K. Usui, T. Kikuchi, K. Tomizaki, T. Kakiyama, H. Mihara
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Issue: 57 Pages: 6394-6396
- DOI
  10.1039/c3cc41632a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] A Novel Array Format for Monitoring Cellular Uptake Using a Photo-Cleavable Linker for Peptide Release2013
- Author(s)
  K. Usui, T. Kikuchi, K. Tomizaki, T. Kakiyama, H. Mihara
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Pages: 6394-6396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] Systematic Screening of the Cellular Uptake of Designed alpha-Helix Peptides2013
- Author(s)
  Kenji Usui, Takuya Kikuchi, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Pages: 2560-2567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] A Peptide Release System using a Photo-cleavable Linker in a Cell Array Format for Cell-toxicity Analysis2013
- Author(s)
  T. Kakiyama, K. Usui, K. Tomizaki, M. Mie, E. Kobatake, H. Mihara
- Journal Title
  
  Polymer J.
  
  Volume: 45 Pages: 535-539
- NAID
  10031166681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] Cell Penetration and Cell-selective Drug Delivery Usingα-Helix Peptides Conjugated with Gold Nanoparticles2013
- Author(s)
  H.J. Park, H. Tsutsumi, H. Mihara
- Journal Title
  
  Biomaterials
  
  Volume: 34 Pages: 4872-4879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24656500
[Journal Article] Sensitive Detection of Small Molecule-Protein Interactions on a Metal-Insulator-Metal Label-Free Biosensing Platform2012
- Author(s)
  A. Syahir, K. Kajikawa, H. Mihara
- Journal Title
  
  Chem. Asia. J.
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22651047
[Journal Article] Gold Nanoparticles Conjugated with Monosaccharide-modified Peptide for Lectin Detection2012
- Author(s)
  H. Tsutsumi, H. Ohkusa, H. Park, T.Takahashi, H. Yuasa, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Pages: 6825-6827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] A Novelβ-Loop Scaffold of Phage-Displayed Peptides for Highly Specific Affinities2011
- Author(s)
  T. Sawada, K. Ishiguro, T. Takahashi, H. Mihara
- Journal Title
  
  Mol. BioSyst.
  
  Volume: 7 Pages: 2558-2562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] A Novel β-Loop Scaffold of Phage-Displayed Peptides for Highly Specific Affinities2011
- Author(s)
  T.Sawada, K.Ishiguro, T.Takahashi, H.Mihara
- Journal Title
  
  Molecular BioSystems
  
  Volume: 7 Issue: 9 Pages: 2558-2562
- DOI
  10.1039/c1mb05085k
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107512
[Journal Article] A Novel Peptide Array Using a Phage Display System for Protein Detection2011
- Author(s)
  T. Sawada, K. Ishiguro, T. Takahashi, H. Mihara
- Journal Title
  
  Chem. Lett.
  
  Volume: 40 Pages: 508-509
- NAID
  10028242940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] Cell Fingerprint Patterns Using Designedα-Helical Peptides to Screen for Cell-specific Toxicity2011
- Author(s)
  K. Usui, T. Kakiyama, K.-Y. Tomizaki, M. Mie, E. Kobatake, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 21 Pages: 6281-6284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] デザインペプチドを用いたプロテインアレイと細胞アレイ2010
- Author(s)
  臼井健二、富崎欣也、三原久和
- Journal Title
  
  化学フロンティア22,生命現象を理解する分子ツール
  
  Pages: 79-87
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] A New Optical Label-Free Biosensing Platform Based on a Metal-Insulator-Metal Structure2010
- Author(s)
  Amir Syahir, Hisakazu Mihara, Kotaro Kajikawa
- Journal Title
  
  Langmuir
  
  Volume: 26 Pages: 6053-6057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651047
[Journal Article] A New Optical Label-Free Biosensing Platform Based on a Metal. Insulator. Metal Structure2010
- Author(s)
  A. Syahir, H. Mihara, K. Kajikawa
- Journal Title
  
  Langmuir
  
  Volume: 26 Pages: 6053-6057
- Data Source
  KAKENHI-PROJECT-22651047
[Journal Article] Protein-Protein Interaction and Screening : Array-based Techniques for Screening Disease-Associated Biomarkers in Predictive/Early Diagnostics2010
- Author(s)
  K.-Y. Tomizaki, K. Usui, H. Mihara
- Journal Title
  
  FEBS Journal
  
  Volume: 277 Pages: 1996-2005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] Poly(amidoamine)dendrimermodified gold surfaces for anomalous reflection of gold (AR) method to detect biomolecular interactions.2009
- Author(s)
  Syahir A, Tomizaki K -Y, Kajikawa K, Mihara H.
- Journal Title
  
  Langmuir 25
  
  Pages: 3667-3674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Selection and structural analysis of de novo proteins from an alpha3beta3 genetic library2009
- Author(s)
  M. T. Jumawid, T. Takahashi, T. Yamazaki, H. Ashigai, H. Mihara
- Journal Title
  
  Protein Science 18
  
  Pages: 384-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Poly(amidoamine)dendrimer modified gold surfaces for anomalous reflection of gold(AR)method to detect biomolecular interactions2009
- Author(s)
  A. Syahir, K-Y. Tomizaki, K. Kajikawa, H. Mihara
- Journal Title
  
  Langmuir 25
  
  Pages: 3667-3674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Poly(amidoamine)dendrimer-modified gold surfaces for anomalous reflection of gold (AR) method to detect biomolecular interactions2009
- Author(s)
  A. Syahir, K. Tomizaki, K. Kajikawa, H. Mihara
- Journal Title
  
  Langmuir 25
  
  Pages: 3667-3674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Peptide and Protein Mimetics Inhibiting the Amyloid beta-Peptide Aggregation2008
- Author(s)
  T. Takahashi, H. Mihara
- Journal Title
  
  Accounts of Chemical Research 41(10)
  
  Pages: 1309-1318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Construction of Multi-functional Extracellular Matrix Proteins that Promote Tube Formation of Endothelial Cells2008
- Author(s)
  M. Nakamura, M. Mie, H. Mihara, M. Nakamura, E. Kobatake
- Journal Title
  
  Biomaterials 29
  
  Pages: 2977-2986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Screening of α-Helical Peptide Ligands Controlling a Calcineurin Phosphatase Activity Bioorg2007
- Author(s)
  K. Usui, K.-Y. Tomizaki, H. Mihara
- Journal Title
  
  Med. Chem. Lett 17
  
  Pages: 167-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] ペプチドライブラリを用いるタンパク質相互作用検出チップ2007
- Author(s)
  富崎欣也、臼井健二、三原久和
- Journal Title
  
  電気化学および工業物理化学 75
  
  Pages: 981-986
- NAID
  10019676065
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Phosphate-Mediated Molecular Memory Driven by Two Different Protein Kinases as Information Input Elements.2007
- Author(s)
  Tomizaki K -Y, Mihara H.
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 8345-8352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Embedding the Amyloid β-Peptide Sequence in Green Fluorescent Protein Inhibits A β 0ligomerization2007
- Author(s)
  Takahashi T, Ohta K, Mihara H
- Journal Title
  
  ChemBioChem 8
  
  Pages: 985-988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Interactions Between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. cerevisiae Proteins2007
- Author(s)
  S. Watanabe, K.-Y. Tomizaki, T. Takahashi, K. Usui, K. Kajikawa, H. Mihara
- Journal Title
  
  Biopolymers(Peptide Science) 88
  
  Pages: 131-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Phosphate-Mediated Molecular Memory Driven by Two Different Protein・Kinases as Information Input Elements2007
- Author(s)
  Tomizaki K-Y, Mihara H
- Journal Title
  
  J. Am. Chem. Soc. 129
  
  Pages: 8345-8352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] タンパク質検出チップ2007
- Author(s)
  富崎欣也、三原久和
- Journal Title
  
  未来材料 7
  
  Pages: 28-38
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] タンパク質分析用バイオチップ2007
- Author(s)
  三原久和
- Journal Title
  
  ケミカルエンジニアリング 52
  
  Pages: 421-427
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Interactions Between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. cerevisiae Proteins2007
- Author(s)
  Watanabe S, Tomizaki K-Y, Takahashi T, UsuiK, Kajikawa K, Mihara H
- Journal Title
  
  Biopolymer 88
  
  Pages: 131-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Screening of α-Helical Peptide Ligands Controlling a Calcineurin-Phosphatase Activity2007
- Author(s)
  Usui K, Tomizaki K-Y, Mihara H
- Journal Title
  
  Bioorg. Med. Chem. Lett. 17
  
  Pages: 167-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Design of Peptides That Form Amyloid-like Fibrils Capturing Amyloid a β1-42 Peptides2007
- Author(s)
  Sato J, Takahashi T, 0shima H, Matsumura S, Mihara H
- Journal Title
  
  Chem. Eur. J. 13
  
  Pages: 7745-7752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System.2006
- Author(s)
  Usui K, Tomizaki K -Y, Ohyama T, Nokihara K, Mihara H.
- Journal Title
  
  Mol. BioSyst. 2
  
  Pages: 113-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Rational design of homogenous protein kinase assay platforms that allow both fluorometric and colorimetric signal readouts2006
- Author(s)
  Kin-ya Tomizaki, Hisakazu Mihara
- Journal Title
  
  Mol.BioSyst. 2
  
  Pages: 580-589
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Rational design of homogenous protein kinase assay platforms that allow both fluorometric and colorimetric signal readouts2006
- Author(s)
  K.-Y. Tomizaki, H. Mihara
- Journal Title
  
  Mol. BioSyst 2
  
  Pages: 580-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Protein-fingerprint data mining of a designed a-helical peptide array2006
- Author(s)
  Usui K, Tomizaki K -Y, Mihara H.
- Journal Title
  
  Mol. BioSyst. 2
  
  Pages: 417-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] A PNA-DNA hybridization chip approach for the detection of β-secretase activity2006
- Author(s)
  S. Sano, K.-Y. Tomizaki, K. Usui, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett 16
  
  Pages: 503-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] Protein-fingerprint data mining of a designed α-helical peptide array2006
- Author(s)
  Kenji Usui, Hisakazu Mihara
- Journal Title
  
  Mol.BioSyst. 2
  
  Pages: 417-420
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] A PNA-DNA Hybridization Chip Approach for the Detection of b-Secretase Activity2006
- Author(s)
  Shusuke Sano, Hisakazu Mihara
- Journal Title
  
  Bioorg.Med.Chem.Lett. 16
  
  Pages: 503-506
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System2006
- Author(s)
  Kenji Usui, Hisakazu Mihara
- Journal Title
  
  Mol.BioSyst. 2
  
  Pages: 113-121
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Protein fingerprint data mining of a designed α-helical peptide array2006
- Author(s)
  K. Usui, K.-Y. Tomizaki, H. Mihara
- Journal Title
  
  Mol. BioSyst 2
  
  Pages: 417-420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] A Novel Peptide Microarray for Protein Detection and Analysis Utilizing a Dry Peptide Array System2006
- Author(s)
  K. Usui, K.-Y. Tomizaki, T. Ohyama, K. Nokihara, H. Mihara
- Journal Title
  
  Mol. BioSyst 2
  
  Pages: 113-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310087
[Journal Article] A Designed Glycopeptide Array for Characterization of Sugar-Binding Proteins Toward a Glycopeptide Chip Technology2005
- Author(s)
  Kenji Usui, Hisakazu.Mihara
- Journal Title
  
  NanoBiotechnology 1
  
  Pages: 191-200
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Anomalous Reflection of Gold Applicable for a Practical Protein-detecting Chip Platform2005
- Author(s)
  Shinya Watanabe, Hisakazu.Mihara
- Journal Title
  
  Molecular BioSystems 1
  
  Pages: 363-365
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] Protein-Detecting Microarrays : Current Accomplishments and Requirements2005
- Author(s)
  K.-Y.Tomizaki, K.Usui, H.Mihara
- Journal Title
  
  Chem Bio Chem 6
  
  Pages: 782-799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Protein-Detecting Microarrays : Current Accomplishments and Requirements.2005
- Author(s)
  Tomizaki K -Y, Usui K, Mihara H.
- Journal Title
  
  ChemBioChem 6
  
  Pages: 782-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17066005
[Journal Article] A Novel Fluorescence Sensing System Using Photochromism-Based Assay (P-CHROBA) Technique for Detection of Target Proteins2005
- Author(s)
  K.-Y.Tomizaki, H.Mihara
- Journal Title
  
  J.Mater.Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Construction and Control of Self-Assembly of Amyloid and Fibrous Peptides2005
- Author(s)
  Hisakazu Mihara
- Journal Title
  
  Bull.Chem.Soc.Jpn 78
  
  Pages: 572-590
- NAID
  10015463114
- Data Source
  KAKENHI-PROJECT-16041211
[Journal Article] A Chromism-Based Assay (CHROBA) Technique for in situ Detection of Protein Kinase Activity2005
- Author(s)
  K.-Y.Tomizaki, J.Xu, H.Mihara
- Journal Title
  
  Bioorg.Med.Chem.Lett. 15
  
  Pages: 1731-1735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Peptide Arrays with Designed Secondary Structure for Protein Characterization Using Fluorescent Fingerprint Patterns2004
- Author(s)
  K.Usui, T.Ojima, M.Takahashi, K.Nokihara, H.Mihara
- Journal Title
  
  Biopolymer 76
  
  Pages: 129-139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Peptide Arrays with Designed α-Helical Structure for Characterization of Proteins from FRET Fingerprint Patterns2004
- Author(s)
  K.Usui, M.Takahashi, K.Nokihara, H.Mihara
- Journal Title
  
  Molecular Diversity 8
  
  Pages: 209-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] Construction of a Protein-Detection System Using a Loop Peptide Library with a Fluorescence Label2003
- Author(s)
  M.Takahashi, K.Nokihara, H.Mihara
- Journal Title
  
  Chem.Biol. 10
  
  Pages: 53-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Journal Article] オミクス研究に向けた設計ペプチドアレイの構築
- Author(s)
  臼井健二、富崎欣也、三原久和
- Journal Title
  
  分析化学
  
  Volume: (印刷中)
- NAID
  10030436925
- Data Source
  KAKENHI-PROJECT-22651047
[Journal Article] "オミクズ"研究に向けた設計ペプチドアレイの構築
- Author(s)
  臼井健二, 富崎欣也, 三原久和
- Journal Title
  
  分析化学
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651047
[Patent] バイオセンシング用基板2008
- Inventor(s)
  梶川浩太郎、三原久和、アミルシャヒルビンハムザー
- Industrial Property Rights Holder
  東京工業大学
- Filing Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-18310087
[Patent] センサ基板及びバイオセンサ2007
- Inventor(s)
  梶川浩太郎、三原久和、アミルシャヒルビンハムザー
- Industrial Property Rights Holder
  東京工業大学
- Filing Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-18310087
[Patent] 特許権2004
- Inventor(s)
  三原久和, 富崎欣也
- Industrial Property Rights Holder
  財団法人理工学振興会
- Industrial Property Number
  2004-045588
- Filing Date
  2004-02-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14350432
[Presentation] Construction of a galactose-modified peptide phage library and screening of peptide ligands binding to galectin-32023
- Author(s)
  Yue Qiu・Hisakazu Mihara・Hiroshi Tsutsumi
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-22K19102
[Presentation] ガラクトース結合タンパク質の解析を指向したリガンド修飾蛍光シリカナノ粒子の創製2023
- Author(s)
  松浦　右京・三原　久和・堤　浩
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-22K19102
[Presentation] 蛍光修飾αヘリックス設計ペプチドを提示したファージライブラリによるgalectin-3検出蛍光バイオセンサーの探索2021
- Author(s)
  橋本匡浩、三木卓幸、Iou Ven Chang、堤　浩、三原久和
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] Construction of photoreactive group-modified phage libraries and selection against hDM22021
- Author(s)
  Keigo Namii、Takayuki Miki、Hisakazu Mihara
- Organizer
  The 58th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 蛍光修飾ファージライブラリを用いたスクリーニングによるgalectin-3検出蛍光バイオセンサーの開発2021
- Author(s)
  橋本匡浩、三木卓幸、Chang Iou Ven、堤　浩、三原久和
- Organizer
  第31回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] ベンゼンスルホンアミド修飾環状ペプチドファージライブラリの構築2020
- Author(s)
  滝聞宏基, Anananuchatku Teerapat, 梶原圭悟, 三木卓幸, 三原久和, 堤浩
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 修飾ファージライブラリによるGalectin-3応答蛍光バイオセンサーの探索2020
- Author(s)
  橋本匡浩, 三木卓幸, Iou Ven Chang, 堤浩, 三原久和
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] Cell-penetrating activity analysis of amphiphilic alpha-helix peptides from designed peptide library2019
- Author(s)
  Mimi Tian, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K22249
[Presentation] Screening of peptide ligands for Galectin-3 using a designed stapled alpha-helix peptide phage library2019
- Author(s)
  Teerapat Anananuchatkul, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K22249
[Presentation] Screening of peptide ligands for Galectin-3 using a designed stapled α-helix peptide phage library2019
- Author(s)
  Teerapat Anananuchatkul, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] Monosaccharide-modified alpha-helix peptide phage libraries for carbohydrate-binding proteins2018
- Author(s)
  Iou Ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] Semisynthetic approach for ligand screening using chemically modified peptide phage libraries2017
- Author(s)
  Hiroshi Tsutsumi, Iou Ven Chang, Teerapat Anananuchatkul, Hisakazu Mihara
- Organizer
  第54回ペプチド討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 両親媒性αヘリックスペプチドの細胞導入特性の解析2017
- Author(s)
  澁谷圭祐、陶欣然、堤浩、三原久和
- Organizer
  日本化学会第97春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 二次構造設計糖ペプチドファージライブラリの構築とレクチン結合性糖ペプチドリガンド探索への応用2017
- Author(s)
  堤浩、Chang IouVen、廣原庸平、三原久和
- Organizer
  日本化学会第97春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 単糖導入ペプチド修飾金ナノ粒子の合成とレクチンタンパク質との相互作用2016
- Author(s)
  白井智子、堤　浩、湯浅英哉、三原久和
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 細胞識別に向けた種々の両親媒性α-ヘリックスペプチドの細胞膜透過活性解析2016
- Author(s)
  堤浩、陶欣然、三原久和
- Organizer
  第10回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] Screening for concanavalin A binders from a mannose-conjugated alpha-helix peptide phage library2016
- Author(s)
  IouVen Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第53回ペプチド討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] A mannose-conjugated α-helix designed peptide phage-library as a tool for the screening of Concanavalin A binding ligands2015
- Author(s)
  IouVen Chang、Yohei Hirohara、Hiroshi Tsutsumi、Hisakazu Mihara
- Organizer
  The 7th International Peptide Symposium
- Place of Presentation
  Singapore
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 単糖修飾β-ループペプチドファージライブラリの構築と糖結合タンパク質結合性ペプチドの探索2015
- Author(s)
  廣原庸平、新井佳菜子、堤　浩、三原久和
- Organizer
  第25回バイオ・高分子シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 細胞選択的な膜透過性を有する設計α-ヘリックスペプチドの機能解析2015
- Author(s)
  堤　浩、陶欣然、三原久和
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] Designed Peptide Libraries for Cell Analyzing Microarrays2013
- Author(s)
  Hisakazu Mihara, Kenji Usui, Hiroshi Tsutsumi, Kiyoshi Nokihara
- Organizer
  6^<th> International Peptide Symposium
- Place of Presentation
  Hawaii
- Invited
- Data Source
  KAKENHI-PROJECT-24656500
[Presentation] Designed Peptide Libraries for Cell Analyzing Microarrays2013
- Author(s)
  H. Mihara, K. Usui, H.Tsutsumi, K. Nokihara
- Organizer
  6th International Peptide Symposium
- Place of Presentation
  Hawaii
- Invited
- Data Source
  KAKENHI-PROJECT-24656500
[Presentation] CONSTRUCTION OF A PHAGE LIBRARY DISPLAYING MANNOSE-MODIFIED PEPTIDES AND SCREENING OF BINDING PEPTIDES TO CONCANAVALIN A2012
- Author(s)
  Kanako Arai, Hiromichi Okura, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第49回日本ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] マンノース修飾ペプチドを提示したファージライブラリの構築とコンカナバリンA結合性ペプチドの探索2012
- Author(s)
  新井佳菜子,大倉裕通,堤浩,三原久和
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] 細胞透過性ペプチド結合金ナノ粒子の細胞との相互作用評価2012
- Author(s)
  西村仁孝, Hyejin Park,堤浩,三原久和
- Organizer
  第61回高分子討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24656500
[Presentation] Peptide Nanofibers toward Cell Engineering Biomaterials2012
- Author(s)
  Hisakazu Mihara
- Organizer
  The 14th Akabori Conference
- Place of Presentation
  Niseko（北海道）
- Year and Date
  2012-09-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107512
[Presentation] Self-Assembling Peptide Materials for Cell Scaffolds2012
- Author(s)
  Hisakazu Mihara
- Organizer
  The 6th Peptide Engineering Meeting
- Place of Presentation
  Atlanta (USA)
- Year and Date
  2012-10-02
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107512
[Presentation] Designed peptide libraries for cell analyses2012
- Author(s)
  Hisakazu Mihara
- Organizer
  2012 International Symposium on Advanced Biological Engineering
- Place of Presentation
  中国
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] αヘリックスペプチド結合金ナノ粒子を用いた細胞導入と細胞選択的ドラッグデリバリ2012
- Author(s)
  Park Hyejin,堤浩,三原久和
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24656500
[Presentation] Designed Peptide Libraries for Cell Analyses2012
- Author(s)
  Hisakazu Mihara
- Organizer
  2012 International Symposium on Advanced Biological Engineering
- Place of Presentation
  Guilin, China
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] αへリックスペプチドを結合した金ナノ粒子の細胞導入活性とガン細胞応用2011
- Author(s)
  Park Hyejin,高橋剛,堤浩,三原久和
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] Construction of fusion materials using self-asssembling peptide nanofibers2011
- Author(s)
  Hisakazu Mihara
- Organizer
  1^<ST> International Symposium on Fusion Materials
- Place of Presentation
  鳥羽
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PUBLICLY-23107512
[Presentation] レクチンに対する結合多様性を有する単糖導入ペプチド修飾金ナノ粒子の創製2011
- Author(s)
  大草寛之,朴恵珍,高橋剛,堤浩,湯浅英哉,三原久和
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] 金の異常反射を利用したプロテアーゼ反応の検出2011
- Author(s)
  田島健一、Amir Syahir、梶川浩太郎、三原久和
- Organizer
  第91日本化学会春季年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22651047
[Presentation] 金の異常反射法による金基板上でのプロテアーゼ反応の検出2011
- Author(s)
  田島健一、アミルシャヒル、梶川浩太郎、三原久和
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22651047
[Presentation] A designed peptide library for protein analyses2010
- Author(s)
  Hisakazu Mihara
- Organizer
  14^<th> Korean Peptide and Protein Symposium
- Place of Presentation
  ソウル
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22651047
[Presentation] Designed peptide libraries for protein and cell analyses2010
- Author(s)
  Hisakazu Mihara
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] Designed peptide libraries for protein and cell analyses2010
- Author(s)
  Hisakazu Mihara
- Organizer
  5thInternational Peptide Symposium/47thJapanese Peptide Symposium
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22651047
[Presentation] Designed peptide chips for protein analyses2008
- Author(s)
  Hisakazu Mihara
- Organizer
  Korean Biochio Conference
- Place of Presentation
  Daejon, Korea
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] Designed peptide chips for protein analyses2008
- Author(s)
  H. Mihara
- Organizer
  Korean Biochip Conference
- Place of Presentation
  Daejon, Korea
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-18310087
[Presentation] Peptide microarrays for protein and cell analyses2007
- Author(s)
  Mihara H
- Organizer
  HITS Bionanotechnology Symposium
- Place of Presentation
  Hanyang University, Ansan, Korea
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] Control of Amyloid Formation by designed Peptides and Proteins2007
- Author(s)
  Takahashi T, Mihara H
- Organizer
  Japanese-Swiss Symposium on Chemical Biology(ISCB2007)
- Place of Presentation
  Lausanne, Swiss (invited)
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] 光切断型ペプチドアレイと細胞アッセイ2007
- Author(s)
  柿山喬、富崎欣也、臼井健二、小畠英理、三原久和
- Organizer
  第56回高分子討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] ペプチドの設計とバイオチップ応用2007
- Author(s)
  三原久和
- Organizer
  第20回生物無機化学夏季セミナー
- Place of Presentation
  湯河原
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] 金の異常反射(AR)を利用したタンパク質検出の感度向上2007
- Author(s)
  Amir Syahir、富崎欣也、梶川浩太郎、三原久和
- Organizer
  日本ケミカルバイオロジー研究会第2回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] Desiged pepttide for protein and cell analyess using peptide libraries2007
- Author(s)
  Mihara
- Organizer
  Modern Soid Phase Peptide synthesis&it's a pplication
- Place of Presentation
  Port Douglas Australia (invited)
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] 設計ペプチドを利用したタンパク質分析チップ2007
- Author(s)
  三原久和
- Organizer
  第4回コンビナトリアル・バイオエンジニアリング会議
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] Highly sensitive anomalous reflection of gold applicable for protein detection2007
- Author(s)
  Amir S, Tomizaki K-Y, Kajikawa K, Mihara H
- Organizer
  4th International Peptide Symposium, Cairns
- Place of Presentation
  Australia
- Data Source
  KAKENHI-PROJECT-17066005
[Presentation] 設計ペプチドを利用したタンパク質分析チップ2007
- Author(s)
  三原久和
- Organizer
  第4回コンビナトリアル・バイオエンジニアリング会議
- Place of Presentation
  大阪
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-18310087
[Presentation] Designed Peptide Microarray for a Protein Chip Technology2006
- Author(s)
  H. Mihara
- Organizer
  Systemic Innovation for Microbial Biotechnology
- Place of Presentation
  Busan. Korea
- Year and Date
  2006-06-19
- Data Source
  KAKENHI-PROJECT-18310087

1. NISHINO Norikazu (40145165)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 高橋剛 (90345380)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TSUTSUMI Hiroshi (70398105)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TOMIZAKI Kinya (90397026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. UENO Akihiko (50091658)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IKEDA Hiroshi (70201910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HAMACHI Itaru (90202259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGIMOTO Naoki (60206430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOHDA Masafumi (50250105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KINBARA Kazushi (30282578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKEDA Kyozaburo (40277851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIRAISHI Kenji (20334039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三木卓幸 (20823991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
14. FUJITA Tomio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKANO Jyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 堤浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 29 results

Mihara Hisakazu 三原 久和

MIHARA Hisakazu 三原 久和

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Co-Researchers

Target-directed phage display method and functional nanoparticles for next generation peptide medicinesPrincipal Investigator

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Analysis of biomolecular dynamics on the cell surface using multifunctional nanoparticle probesPrincipal Investigator

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Construction of a Peptide Drug Discovery Platform Using Chemically Modified Peptide Phage LibrariesPrincipal Investigator

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Development of various functional peptides for biochips analyzing cancer cellsPrincipal Investigator

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Construction of a cell-analyzing biochipPrincipal Investigator

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自己組織化ペプチドを用いるナノファイバーの構築と融合マテリアル展開Principal Investigator

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Construction of functional peptide ligands toward peptide biochipsPrincipal Investigator

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Construction of label-free biochips using anomalous reflection of goldPrincipal Investigator

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ペプチドを用いるタンパク質アミロイドの形成機構解析と制御Principal Investigator

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Construction of Protein detection Chips Using Peptide ArraysPrincipal Investigator

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Development of Novel Chemical Tools, Materials and Devices for Precise and Digital Analysis of Single Cell

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アルツハイマー病アミロイド高感度検出のためのチップテクノロジー創製Principal Investigator

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ゲノム情報を利用する新規プロテインチップの開発Principal Investigator

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Mihara Hisakazu 三原久和

MIHARA Hisakazu 三原久和