Masayoshi Kuwahara 桑原正貴

… Alternative Names

KUWAHARA MASAYOSHI 桑原正貴

KUWAHARA Masayoshi 桑原正貴

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Researcher Number	30205273
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京大学, 大学院農学生命科学研究科(農学部), 教授 2016 – 2020: 東京大学, 大学院農学生命科学研究科(農学部), 教授 2014 – 2015: 東京大学, 農学生命科学研究科, 教授 2012: 東京大学, 大学院・農学生命科学研究科, 教授 2012: 東京大学, 農学生命科学研究科, 教授 … More 2010 – 2011: 東京大学, 大学院・農学生命科学研究科, 准教授 2005: 東京大学, 大学院農学生命科学研究科, 助教授 1998 – 2005: 東京大学, 大学院・農学生命科学研究科, 助教授 1996 – 1997: 東京大学, 大学院・農学生命科学研究科, 助手 1992 – 1995: 東京大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator Applied veterinary science / Basic Section 53020:Cardiology-related / Veterinary medical science / Applied veterinary science Except Principal Investigator Applied veterinary science / 環境影響評価(含放射線生物学) / Basic veterinary science/Basic zootechnical science / Medium-sized Section 51:Brain sciences and related fields / Fundamental nursing / Integrative animal science / Laboratory animal science / Clinical veterinary science / Animal production science
Keywords	Principal Investigator 中皮細胞 / アクチン / 細胞骨格 / 細胞内カルシウム / 自律神経系 / 自律神経 / 透過性 / ヒスタミン / トロンビン / 組織幹細胞 … More / 遅発性心毒性 / 遅発性 / 不整脈 / 高血圧 / ドキソルビシン / 心毒性 / 抗がん剤 / 薬剤誘発性QT延長症候群 / ゲノム編集技術 / Kcnq1遺伝子 / ウサギ / 安全性薬理 / Body temperature / Heart rate variability / Chronobiology / Telemetry / Cytokine / Lipopolvsaccaride / Autonomic nervous system / Cardiovascular system / 体温 / 心拍変動解析 / 時間生物学 / テレメトリー / 炎症性サイトカイン / リポポリサッカライド / 心血管系 / 日内変動 / 加齢 / 免疫 / 睡眠 / 伸展刺激 / ブラジキニン / ブラディキニン / 電位依存性カルシウムチャネル / エンドセリン … More Except Principal Investigator MuRF-1 / NSAIDs / ACTH / 5AzC / ENU / chemicals / fetal brain / cell cycle arrest / apoptosis / SHR / DEP / 循環器障害 / 繁殖障害 / 大気汚染 / ディーゼル排気微粒子 / モルモット / ヒスタミン / 抑制性介在性神経細胞 / SIDS / 抑制性介在神経 / 妊娠 / 孤束核 / グリシン / GABA / 副流煙 / 乳幼児突然死 / 慢性疾患患者 / 積極的看護介入 / 副交感神経活動リザーブ / 生理学 / 老化 / 神経科学 / 長期増強 / シナプス / 記憶・学習 / Ca2+ホメオスタシス / 加齢 / シナプス可塑性 / ubiquitin / μ-calpain / cardiac conduction / vacuolar degeneration / purkinje fiber / canine X-linked muscular dystrophy / muscular dystrophy / 心電図異常 / 空砲変性 / ユビキチン / カルパイン / 心刺激伝導系 / 空胞変性 / プルキンエ線維 / 筋ジストロフィー犬 / 筋ジストロフィー / heart rate / blood pressure / opioid / nociception / pain / cortisol / 手術侵襲 / 犬 / VAS / カルプロフェン / オピオイド / 非ステロイド性抗炎症薬 / 疼痛 / 全静脈麻酔 / リドカイン / ケタミン / フェンタニル / 麻薬 / 心拍数 / 血圧 / 麻薬性鎮痛薬 / 侵害刺激 / 痛み / コルチゾール / Growth / Myometrial contractility / Reactive oxygen species / Air pollution / Abortion / Genital organs / Cardiovascular system / Diesel exhaust particle / C57BLマウス / ディーゼル排気ガス / 心筋細胞 / 細胞傷害性 / 成長 / 子宮収縮 / 活性酸素種 / 流産 / 生殖器影響 / 循環器影響 / A ra-C / mechanisms / mistosis / rpL4 / 細胞周期停止 / アポトーシス / ラット胎盤 / ラット胎仔中枢神経 / Ethylnitrosourea / apotosis / 5-azacytidine / ethylnitrosourea / placental toxicity / fetotoxicity / NMDA / Ara-C / mechaism / ACLE / Bronchoionstriction / Vagal nerro / Bradykinin / ACL / Histamine / Guinea pig / Airway hypersensitivity / モデル動物 / 咳反射 / クエン酸 / カルバコール / 気管平滑筋 / アセチルコリンエステラーゼ / 気道収縮 / 迷走神経 / ブラジキニン / アセチルコリン / 気道過敏症 / vole / telemetry system / power spectrum / FFT method / analysis of heart rate variability / noninvasive analytical method / autonomic nervous function / 哺乳動物 / 長時間心電図記録 / パワースペクトラム / ハタネズミ / テレメトリーシステム / パワースペクトル / 高速フーリエ変換法 / 心拍変動解析 / 非侵襲的評価法 / 自律神経機能 / 加速度センサ / エンドトキシン / ノンレム睡眠 / レム睡眠 / ひずみセンサ / 眼瞼 / 脳波 / 睡眠状態 / ラット / 喉頭 / カプサイシン / C線維 / 三叉神経 / 鼻粘膜 Less

Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?
- Principal Investigator
  
  関澤信一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  The University of Tokyo
athogenesis of delayed cardiotoxicity of anticancer drugs focusing on the autonomic nervous system and its stem cellsPrincipal Investigator
- Principal Investigator
  
  Masayoshi Kuwahara
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
Effects of nursing interventions increasing parasympathetic nervous activity in chronic disease patients
- Principal Investigator
  
  Yamamoto Machiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fundamental nursing
- Research Institution
  Ibaraki Christian University
The role of Ca2+ homeostasis in hippocampal synaptic transmission and plasticity
- Principal Investigator
  
  Ito Koichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  The University of Tokyo
Development of animal models for safety assessment of drugs using genome editing technology and its applicationPrincipal Investigator
- Principal Investigator
  
  KUWAHARA MASAYOSHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Veterinary medical science
- Research Institution
  The University of Tokyo
Development of the method for status assesment of cattle by monitoring sleep stage.
- Principal Investigator
  
  Yayou Ken-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  National Agriculture and Food Research Organization
  National Institute of Agrobiological Sciences
Chronobiological study for role of nervous and immune systems in sleep regulationPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Masayoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
THE RELEVANCE OF THE SELECTIVE DAMAGE OF PURKINJE FIBER AND THE ABNORMAL ELECTROCARDIOGRAM IN CANINE X-LINKED MUSCLAR DYSTROPHY
- Principal Investigator
  
  SHIMATSU Yoshiki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (NCNP)
Development of objective criteria of pain in animals.
- Principal Investigator
  
  NISHIMURA Ryohei
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  The University of Tokyo
Mechanisms of chemical-induced fetal brain toxicity
- Principal Investigator
  
  DOI Kunio
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
Effects of diesel exhaust particulate (DEP) on genital organs and cardiovascular system
- Principal Investigator
  
  TSUBONE Hirokazu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  THE UNIVERSITY OF TOKYO
ディーゼル排気ガス粒子(DEP)の循環機能ならびに胎児毒性に関する基礎的研究
- Principal Investigator
  
  局博一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  The University of Tokyo
Chronobiological study on interactions between cardiovascular and neuroimmunological functionPrincipal Investigator
- Principal Investigator
  
  KUWAHARA Masayoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  THE UNIVERSITY OF TOKYO
中皮細胞と内皮細胞のバリアー機能に関する研究Principal Investigator
- Principal Investigator
  
  桑原正貴
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
中皮細胞の機械的伸展に対する細胞応答性に関する研究Principal Investigator
- Principal Investigator
  
  桑原正貴
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
中皮細胞の物質透過性調節に関する研究Principal Investigator
- Principal Investigator
  
  桑原正貴
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
Basic research in pathophysiological mechanisms on airway hypersensitivity
- Principal Investigator
  
  SUGANO Shigeru
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
鼻・喉頭粘膜におけるC線維の感覚受容機構と神経ペプチドの放出に関する研究
- Principal Investigator
  
  TSUBONE Hirokazu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
中皮細胞に対する生理活性物質の影響Principal Investigator
- Principal Investigator
  
  桑原正貴
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
Establishment of noninvasive analytical methods for autonomic nervous function in mammals and their application
- Principal Investigator
  
  SUGANO Shigeru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2017 2016 2015 2011

All Journal Article Presentation

[Journal Article] Effects of environmental enrichment on autonomic nervous activity in NSY mice2020
- Author(s)
  Kentaro Kaneko, Akitoshi Chikamoto, Julia Chu-Ning Hsu, Ryota Tochinai, Shin-ichi Sekizawa, Machiko Yamamoto, Masayoshi Kuwahara
- Journal Title
  
  Exp. Anim.
  
  Volume: 69 Issue: 2 Pages: 161-167
- DOI
  10.1538/expanim.19-0103
- NAID
  130007835091
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12091, KAKENHI-PROJECT-17H05107
[Journal Article] Age-dependency of the serum oxidative level in the senescence-accelerated mouse prone 82016
- Author(s)
  Taniguchi S, Hanafusa M, Tsubone H, Takimoto H, Yamanaka D, Kuwahara M, Ito K
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 78 Issue: 8 Pages: 1369-1371
- DOI
  10.1292/jvms.16-0204
- NAID
  130005261468
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08070
[Journal Article] Nicotine treatment reduces LPS-induced sickness responses in telemetry monitoring rats2011
- Author(s)
  Kojima H, Ito K, Tsubone H, Kuwahara. M.
- Journal Title
  
  J. Neuroimmunol
  
  Volume: 234(1-2) Pages: 55-62
- Data Source
  KAKENHI-PROJECT-22580348
[Presentation] Can slow breathing exercise improve the autonomic nervous imbalance in chronic kidney disease patients?2019
- Author(s)
  Kentaro Kaneko, Shin-ichi Sekizawa, Ryota Tochinai, Machiko Yamamoto, Masayoshi Kuwahara
- Organizer
  International Congress on Electrocardiology 2019, Joint meeting of ISHNE and ISE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12091
[Presentation] Can slow breathing exercise improve the autonomic nervous imbalance in chronic kidney disease patients ?2019
- Author(s)
  Kentaro Kaneko, Shin-ichi Sekizawa, Ryota Tochinai, Machiko Yamamoto, Masayoshi Kuwahara
- Organizer
  International Congress on Electrocardiology 2019, Joint meeting of ISHNE and ISE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12091
[Presentation] 糖尿病モデルマウスにおける病態と自律神経系機能に及ぼす環境エンリッチメントの影響2018
- Author(s)
  金子健太郎、近本明俊、関澤信一、山本真千子、桑原正貴
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17K12091
[Presentation] Evaluation of autonomic nervous functions in chronic kidney disease patients by tone-entropy analysis2017
- Author(s)
  Kentaro Kaneko, Machiko Yamamoto, Masayoshi Kuwahara
- Organizer
  The 44th International Congress on Electrocardiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12091
[Presentation] 極低用量LPS投与後の子ウシの休息行動の評価2016
- Author(s)
  籾田康介・吉田茉純・宗田吉広・石崎宏・桑原正貴・小針大助・矢用健一
- Organizer
  応用動物行動学会・日本家畜管理学会合同　2016年度春季大会
- Place of Presentation
  日本獣医生命科学大学
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-26450396
[Presentation] 海馬CA1シナプス活動に与えるバニリンの効果に関する検討2016
- Author(s)
  谷口紗貴子、山中大介、伊藤公一、桑原正貴
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08070
[Presentation] Resting behaviour of steers after a low dose of lipopolysaccharide.2016
- Author(s)
  Momita K, Yoshida M, Kuwahara M, Kohari D, Ishizaki H, Muneta M, Yayou K
- Organizer
  The 50th Congress of the International Society for Applied Ethology
- Place of Presentation
  the University of Edinburgh（UK・Edinburgh）
- Year and Date
  2016-07-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450396
[Presentation] 群飼育への移行に伴う子牛の生体機能変化に関する研究2016
- Author(s)
  吉田　茉純・石崎　宏・宗田　吉広・矢ヶ部　陽子・桑原　正貴・矢用　健一
- Organizer
  応用動物行動学会・日本家畜管理学会合同　2016年度春季大会
- Place of Presentation
  日本獣医生命科学大学
- Year and Date
  2016-03-30
- Data Source
  KAKENHI-PROJECT-26450396
[Presentation] 自律神経系機能の変化から牛の病態発症を検出する試み2016
- Author(s)
  吉田茉純・籾田康介・宗田　吉広・石崎　宏・桑原　正貴・矢用健一
- Organizer
  第93回日本獣医麻酔外科学会・第105回日本獣医循環器学会2016年秋季合同学会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26450396
[Presentation] Acetyl-L-carnitine improves age-dependent impairment of LTP of the senescence-accelerated mouse prone 82016
- Author(s)
  Taniguchi S, Takimoto H, Hanafusa M, Tsubone H, Yamanaka D, Kuwahara M, Ito K
- Organizer
  46th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08070
[Presentation] Vanillin protects the hippocampal neuronal function from age-related deterioration2016
- Author(s)
  Ito K, Tanicughi S, Hanafusa M, Tsubone H, Yamanaka D, Kuwahara M
- Organizer
  46th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08070
[Presentation] Effects of intranasal administration of arginine vasopressin in Holstein steers2015
- Author(s)
  Yoshida M, Momita K, Kuwahara M, Kasuya E, Sutoh M, Yayou K
- Organizer
  The 49th Congress of the International Society for Applied Ethology
- Place of Presentation
  北海道大学
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450396
[Presentation] 実験的初期感染状態における生体機能評価2015
- Author(s)
  吉田茉純, 宗田吉広, 石崎宏, 籾田康介, 桑原正貴, 矢用健一
- Organizer
  日本畜産学会第120回大会
- Place of Presentation
  酪農学園大学
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26450396

1. TSUBONE Hirokazu (30142095)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. DOI Kunio (70155612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SUGANO Shigeru (70111482)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 石井圭司 (20313083)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 関澤信一 (80760420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 栃内亮太 (90833997)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Yayou Ken-ichi (40343967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. OZAKI Hiroshi (30134505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NISHIHARA Masugi (90145673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ONO Ken-ichiro (50111480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAYAMA Hiroyuki (40155891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NISHIMURA Ryohei (80172708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SASAKI Nobuo (60107414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OHNO Koichi (90294660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MOCHIZUKI Manabu (90261958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SHIMATSU Yoshiki (90373406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. WAKAO Yoshito (20063969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKEDA Shin'ichi (90171644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Ito Koichi (50330874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. Yamamoto Machiko (20295380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石田三佳 (10391369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 金子健太郎 (40714358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. 尾形優 (10824732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 河野かおり (60619625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TANIGUCHI Sakiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. MACHIKO Yamamoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Masayoshi Kuwahara 桑原 正貴

KUWAHARA MASAYOSHI 桑原 正貴

KUWAHARA Masayoshi 桑原 正貴

Research Projects

Research Products

Co-Researchers

Principal Investigator

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athogenesis of delayed cardiotoxicity of anticancer drugs focusing on the autonomic nervous system and its stem cellsPrincipal Investigator

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Development of animal models for safety assessment of drugs using genome editing technology and its applicationPrincipal Investigator

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Research Institution

Principal Investigator

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Research Field

Research Institution

Chronobiological study for role of nervous and immune systems in sleep regulationPrincipal Investigator

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Research Institution

Principal Investigator

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Principal Investigator

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Chronobiological study on interactions between cardiovascular and neuroimmunological functionPrincipal Investigator

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中皮細胞と内皮細胞のバリアー機能に関する研究Principal Investigator

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Masayoshi Kuwahara 桑原正貴

KUWAHARA MASAYOSHI 桑原正貴

KUWAHARA Masayoshi 桑原正貴