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YOSHIMURA Shinichi  吉村 眞一

ORCIDConnect your ORCID iD *help
… Alternative Names

吉村 慎一  ヨシムラ シンイチ

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Researcher Number 30230808
Other IDs
Affiliation (based on the past Project Information) *help 2012: 東海大学, 医学部, 講師
2009: 東海大学, 医学部, 講師
1997 – 2004: 東海大学, 医学部, 講師
1993 – 1995: Assistant Professor Department of Molecular Life Science, 医学部, 講師
1991 – 1992: 東海大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
Except Principal Investigator
Human pathology / Obstetrics and gynecology / Experimental pathology / 広領域 / 体育学 / Applied health science / Human pathology
Keywords
Principal Investigator
Apolipoprotein A1 / Apolipoprotein B100 / Renal failure / Diabetes mellitus / Pre-eclampsia / Lipidperoxide reducing activity / Lipid hydroperoxide / 過酸化脂質還元酵素 / 腎不全 / 糖尿病 … More / 妊娠中毒症 / アポリポプロテインA1 / アポリポプロテインB100 / 過酸化脂質還元活性 / 過酸化脂質 / selenium / plasma type / human / chromosome mapping / gene / glutathione peroxidase / セレニウム / 腎臓 / セレン / 血漿型 / ヒト / 染色体座位 / 遺伝子 / グルタチオン・ペルオキシダーゼ … More
Except Principal Investigator
免疫組織化学 / Immunohistochemistry / ホメオボックス蛋白 / ホメオボックス / Pit-1 / 転写因子 / MHC / 中枢神経系 / c-fos / muscle damage / amino acid uptake / weight-lifting exercise / TSH / GATA2 / Apolipoprotein A1 / Fibronectin / Integrin / Cell adhesion / Homeobox gene / Homeobox protein / プログラム細胞死 / フィブロネクチン / インテグリン / 細胞接着 / ホメオボックス遺伝子 / 抗体 / ヒト / 下垂体 / 脂質過酸化 / キノリン酸 / endotherial cells / non-classical MHC class I / classical MHC class I / Immuno-Histochemistry / Expression analysis / Central Nervous System / H2 molecule / H2遺伝子 / 血管内皮細胞 / 非古典的クラスI分子 / 古典的クラスI分子 / 免疫染色 / 発現解析 / H2分子 / H-Thymidine / serotonin / norepinephrine / fatigue resistance capacity / Muscle Damage / Fatigue Resistance / ^<14>C-Leucine / Creatine Kinase / 筋力トレーニング / 視床下部 / Anabolic steroid / 細胞周期 / 細胞増殖 / 培養細胞 / 筋芽細胞 / 蛋白代謝 / 代償性筋肥大 / ^3H-Thymidine / セロトニン / ノルアドレナリン / fatigue resistance / transcription factors / gonadotropin / immunohistochemistry / pituitary adenomas / pituitary cells / GATA-2 / RT-PCR / ゴナドトロピン / 下垂体腺腫 / 下垂体細胞 / thyroid papillary carcinoma / PAS staining / poly (ADP-ribose) / mouse model / single-stranded DNA / cell death / magntosis / lactating breast / アポトーシス / ポリADPリボース / 実験モデル(ラット) / 離乳 / 甲状腺乳頭癌 / PAS染色 / poly(ADP-ribose) / マウスモデル / 一本鎖DNA / 細胞死 / magentosis / 授乳期乳腺 / Pre-eclampsia / apolipoprotein B100 / lipid peroxide reducing enzyme / Lipidperoxide / アポリポプロテインA1 / 妊娠中毒症 / Apolipoprotein B100 / 過酸化脂質還元酵素 / 過酸化脂質 / Extrathymic T-lymphocyte / B-1 lymphocye / Hemophilus influenae / Labeled antigen method / Immunoelectron microscopy / Intraepithelial lymphocyte / Reticular mucosa / Palatine tonsil / 免疫電顕法 / 酵素抗源法 / 酵素抗体法 / インフルエンザ菌 / ヒト口蓋扁桃 / インフルエンザ杵菌 / 胸腺外分化T細胞 / B-1細胞 / インフルエンザ杆菌 / 酵素抗原法 / 上皮細胞間リンパ球 / 網状粘膜 / 口蓋扁桃 / PCNA / HOX4B / インラグリン / マウス / ホメオドメイン / 免疫組織科学 / Recombinant Protein / Antibody / Homeobox Gene / Mouse / Human / 蛋白精製 / マルト-ス結合蛋白 / 大腸菌発現ベクタ- / リコンビナント / 発生 / 蛋白質 / 抗酸化物質 / 老化 / ノックアウトマウス / 脂質結合たんぱく質 / コエンザイムQ10 / ノッ クアウトマウス / 脂質結合タンパク質 / 脂質 / サポシン / プロサポシン / コエンザイム Q10 / Anterior Pituitar / Cell to cell interaction / NOTCH ligand / Pituitary Adenoma / Translocation / Wnt signaling / NOTCH receptor / Pitutary Adenoma / Anterior Pituitary / Wntシグナル / Notchシグナル / GH3 / PKC / COS細胞 / ルシフェラーゼ / 成長ホルモン / 核移行シグナル / Green Fluorescent Protein / Pit1 / ハンチントン病様病変 / グルタチオン・ペルオキシダーセ / 神経細胞壊死 / 線条体 / グルタチオン・ペルオキシダ-ゼ / グリア細胞 / 神経細胞死 / ハンチントン病 Less
  • Research Projects

    (16 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (23 People)
  •  Biological relevance of Coenzyme Q10 binding protein.-Study with prosaposin knockout animal and cell lines-

    • Principal Investigator
      YAMAMOTO Yorihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Tokyo University of Technology
  •  Molecular pathology for functional differentiation of human pituitary adenomas : New development of NOTCH signaling pathway.

    • Principal Investigator
      OSAMURA Yoshiyuki
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Functional analysis of MHC class I molecules in the neuronal cells of central nervous

    • Principal Investigator
      INOKO Hidetoshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      Tokai University
  •  Molecular Mechanisms for Functional Differentiation of Pituitary Cells and Pituitary Adenomas

    • Principal Investigator
      OSAMURA yoshiyuki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Relationship among anabolic androgenic steroid, weight-lifting exercise and physiological functions.

    • Principal Investigator
      TAMAKI Tetsuro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      体育学
    • Research Institution
      Tokai University
  •  下垂体特異的転写因子の核移行の分子機構とその病理学的意義-蛍光蛋白Green Fluorescent Protein (GFP)との融合遺伝子導入法による解析-

    • Principal Investigator
      OSAMURA Yoshiyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University
  •  Purification of lipid hydroperoxide reducing proteins from blood plasma, and analysis of its clinical rolesPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Shinichi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokai University
  •  The significance of polyADP ribosylation in 'magentosis', a new type of cell death: Molecular pathologic approaches to magentosis in a regressing stage of human lactating breast and other hormone-responsive organs

    • Principal Investigator
      TSUTSUMI Yutaka
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University
  •  Clinical roles of plasma phosphatidylcholine hydroperoxide-reducing activity in the development of pre-eclampsia

    • Principal Investigator
      IWASAKI Katuhiko
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tokai University
  •  Immunologic significance of intraepithelial lymphocytes in human palatine tonsils : Morphofunctional approach using immunoelectron microscopy and labeled antigen method

    • Principal Investigator
      TSUTSUMI Yutaka
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University School of Medicine
  •  Molecular and pathological study on the expression of homeobox genes in mature and immature tissues.

    • Principal Investigator
      MORIUCHI Tetsuya
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Tokai University School of Medicine
  •  Studies on the expression of class I homeobox proteins in fetal tissues and immature cells

    • Principal Investigator
      IWASAKI Katsuhiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tokai University School of Medicine
  •  神経細胞の変性、壊死における脂質過酸化とその防御、修復因子の意義

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  The human plasma glutathione peroxidase gene ; organization, nucleotide sequence and localization to chromosome 5q32.Principal Investigator

    • Principal Investigator
      YOSHIMURA Shinichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokai University School of Medicine
  •  キノリン酸による脂質過酸化亢進とラット線条体神経細胞の変性、壊死:脂質過酸化修復因子(グルタチオン・ペルオキシダ-ゼ)の変動による病変の修飾

    • Principal Investigator
      渡辺 慶一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  A study on cell proliferation and differentiation using antibody against human homeodomain protein.

    • Principal Investigator
      MORIUCHI Tetsuya
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokai University School of Medicine

All 2012 2011 2010 2002 Other

All Journal Article Presentation

  • [Journal Article] A basolateral sorting motif in the MICA cytoplasmic tail.2002

    • Author(s)
      Suemizi H, Radosavljevic M, Kimura M, Sadahiro S, Yoshimura S Bahrain S, Inoko H
    • Journal Title

      Proc Natl Acad Sci USA 99

      Pages: 2971-2976

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14209015
  • [Presentation] ヒト・プロサポシン過剰発現マウスにおけるコエンザイムQとビタミンEの体内動態2012

    • Author(s)
      関学,浅利真司,長尾美好,山本順寛,吉村眞一
    • Organizer
      日本コエンザイムQ協会研究会
    • Place of Presentation
      東京都
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] コエンザイムQ結合蛋白質プロサポシン発現量改変株の酸化ストレスに対する感受性2012

    • Author(s)
      ジョン・チュンユン, 長嶋康平, 大泉美希子, 鈴木優, 森内寛, 加柴美里, 吉村眞一, 山本順寛
    • Organizer
      日本コエンザイムQ協会第9回研究会
    • Place of Presentation
      東京(東京工科大学)
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] コエンザイムQ結合蛋白質プロサポシン発現量改変株の酸化ストレスに対する感受性2012

    • Author(s)
      ジョン・チュンユン,長嶋康平,大泉美希子,鈴木優,森内寛,加柴美里,吉村眞一,山本順寛
    • Organizer
      日本コエンザイムQ協会研究会
    • Place of Presentation
      東京都
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] ヒト・プロサポシン過剰発現マウスにおけるコエンザイムQとビタミンEの体内動態2012

    • Author(s)
      関学, 浅利真司, 長尾美好, 山本順寛, 吉村眞一
    • Organizer
      日本コエンザイムQ協会第9回研究会
    • Place of Presentation
      東京(東京工科大学)
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] プロサポシン遺伝子の改変で細胞内CoQ10の量とその酸化還元状態が変わる2011

    • Author(s)
      加柴美里,大泉美希子,鈴木優,澤村佳美,寺嶋政之,長嶋康平,及川慎吾,ジョン・チュンユン,森内寛,吉村眞一,山本順寛
    • Organizer
      日本酸化ストレス学会関東支部会
    • Place of Presentation
      東京都
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] ヒト・プロサポシン過剰発現マウスにおけるCoQ含量とサポシンBの組織内分布2011

    • Author(s)
      吉村眞一,長尾美好,浅利真司,川合巧真,関学,内野晋也,加柴美里,山本順寛,大塚正人,猪子英俊
    • Organizer
      日本コエンザイムQ協会研究会
    • Place of Presentation
      東京都
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] コエンザイムQ10結合タンパク質プロサポシンファミリーの生理的意義に関する考察2011

    • Author(s)
      山本順寛, 加柴美里, 吉村眞一
    • Organizer
      日本コエンザイムQ協会第8回研究会
    • Place of Presentation
      東京工科大学(東京都)
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] ヒト・プロサポシン過剰発現マウスにおけるCoQ含量とサポシンBの組織内分布2011

    • Author(s)
      吉村眞一, 長尾美好, 浅利真司, 川合巧真, 関学, 内野晋也, 加柴美里, 山本順寛, 大塚正人, 猪子英俊
    • Organizer
      日本コエンザイムQ協会第8回研究会
    • Place of Presentation
      東京工科大学(東京都)
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] コエンザイムQ10結合タンパク質プロサポシンファミリーの生理的意義に関する考察2011

    • Author(s)
      山本順寛,加柴美里,吉村眞一
    • Organizer
      日本コエンザイムQ協会研究会
    • Place of Presentation
      東京都
    • Year and Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] Saposin B and its precursor protein prosaposin play key roles in absorption and transfer of CoQ102010

    • Author(s)
      Yorihiro Yamamoto, Misato Kashiba, Shinichi Yoshimura
    • Organizer
      The 6^<th> Conference of the International Coenzyme 10 Association
    • Place of Presentation
      Bedford Hotel, Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] Saposin B and its precursor protein prosaposin play key roles in absorption and transfer of CoQ102010

    • Author(s)
      Yorihiro Yamamoto, Misato Kashiba, and Shinichi Yoshimura
    • Organizer
      The 6th Conference of the InternationalCoenzyme 10 Association
    • Place of Presentation
      Bedford Hotel, Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] エクソン8含有プロサポシンの脂質結合能

    • Author(s)
      及川慎吾,柿澤祐樹,森内 寛,吉村眞一,山本順寛
    • Organizer
      第10回コエンザイムQ協会研究会
    • Place of Presentation
      東京(東京工科大学)
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] コエンザイムQ10結合タンパク質プロサポシンの血漿レベルとリポたんぱく質との相互作用

    • Author(s)
      宮内優樹,緋田哲也,永瀬 翠,森内 寛,加柴美里,吉村眞一,山本順寛
    • Organizer
      第10回コエンザイムQ協会研究会
    • Place of Presentation
      東京(東京工科大学)
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] CoQ10結合蛋白質プロサポシン発現量改変株の細胞内CoQ10量と活性酸素量の変動

    • Author(s)
      ジョン・チュンユン,長嶋康平,森内 寛,加柴美里,吉村眞一,山本順寛
    • Organizer
      第10回コエンザイムQ協会研究会
    • Place of Presentation
      東京(東京工科大学)
    • Data Source
      KAKENHI-PROJECT-22500681
  • [Presentation] ミクロ2次元電気泳動を用いたCoQ結合タンパク質サポシンBの定量法の開発

    • Author(s)
      野村剛,田中秀幸,加柴美里,森内寛,吉村眞一,山本順寛,藤沢章雄
    • Organizer
      第10回コエンザイムQ協会研究会
    • Place of Presentation
      東京(東京工科大学)
    • Data Source
      KAKENHI-PROJECT-22500681
  • 1.  TAKEKOSHI Susumu (70216878)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  TSUTSUMI Yutaka (80138643)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  OSAMURA Yoshiyuki (10100992)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MORIUCHI Tetsuya (20174394)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TANIGUCHI Yasushi (30207188)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  IWASAKI Katsuhiko (10119646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  UMEMURA Shinobu (20276794)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KAJIWARA Hiroshi (20317754)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KIMURA Minoru (10146706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  渡辺 慶一 (00055865)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  松島 一士 (70209542)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  MATSUNO Akira (00242058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TERAMOTO Akira (60231445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YAMAMOTO Yorihiro (60134475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 15.  KASHIBA Misato (80338186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 16.  YASUDA Masanori (50242508)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  INOUE Kinji (50091963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAMAKI Tetsuro (10217177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  UCHIYAMA Shuichi (80256164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  INOKO Hidetoshi (10101932)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  ANDO Asako (40101935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YAMAMORI Tetsuo (80260206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  山形 哲司 (00338766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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