kasahara kazuo 笠原寿郎

… Alternative Names

KASAHARA Kazuo 笠原寿郎

KASAHARA Toshio 笠原寿郎

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Researcher Number	30272967
Other IDs
External Links
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2023: 金沢大学, 医学系, 准教授 2022: 日本医科大学, 医学部, 教授 2011: 金沢大学, 大学病院, 講師 2003 – 2005: 金沢大学, 医学部附属病院, 講師 2004: 金沢大学, 医学系研究科, 講師 1999: 金沢大学, 医学部・附属病院, 講師 1995 – 1998: 金沢大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Tumor therapeutics / Clinical oncology / Respiratory organ internal medicine Except Principal Investigator Medical systems / Basic Section 52040:Radiological sciences-related / Basic Section 90130:Medical systems-related / Respiratory organ internal medicine / Radiation science / Respiratory organ internal medicine / Tumor therapeutics / Tumor diagnostics
Keywords	Principal Investigator 肺癌 / cMet / ｃMet / Topoisomerase I / アポトーシス / シスプラチン / 細胞障害性抗癌薬 / Kras変異陽性肺癌 / EGFR遺伝子変異陽性肺癌 / HMGB1 … More / カルレティキュリン / パクリタキセル / ペメトレキセド / オートファジー / 細胞老化 / 免疫原性細胞死 / MET / 発現解析 / cMET / Met阻害剤 / HGF / シグナル伝達 / 個別化療法 / 非小細胞肺癌 / Toppisomerase I / MET遺伝子 / Lung cancer / 分子標的治療 / Toposioemrase I / トロンボキサンA_2 / MAPキナーゼ / カスパーゼ / 血小板活性化因子 / トロンポキサンA2 … More Except Principal Investigator TAE / 動物実験 / 癌 / EMC / 癌治療 / 誘導加温 / 脂質メディエーター / 異常検出 / 予後予測 / 胸部X線動画像 / 深層学習 / 肺機能診断 / 低線量X線動画像 / 動的呼吸機能検査 / 呼吸器外科学 / 肺機能検査 / 生体分子 / 脂質 / アレルギー・ぜんそく / 呼気凝縮液 / 病態診断 / 尿 / 血液 / 慢性咳嗽 / 機能イメージング開発 / 画像診断学（含放射線診断学） / 医学物理学 / 生理学 / 情報工学 / 画像 / 動態 / イメージング / X線 / 呼吸 / 画像解析 / 放射線 / 肺機能 / Embolism medical treatment / heating for deep-seated cancer / medical device / high frequency power source / nano bio / induction heating / cancer treatment / VX-2 / ガン治療 / DM / 磁気分離 / 塞栓療法 / 深部加温 / 医用機器 / 高周波電源 / ナノバイオ / One-dimensional heat conduction simulation / Ferrite / Applicator / Ritz wire / Cancer treatment / Induction heating / 共振鋭度 / シミュレーション / 小型化 / 小電力化 / 1次元熱伝導シミュレーション / フェライト / アプリケータ / リッツ線 / Guinea pigs / Lipid mediators / Neuropeptides / Autonomic nerve system / beta-blockers / ultrasonically nebulized distillled water / Alcohol-induced asthma / Specific bronchial hyperresponsiveness / トロンボキサンA2 / ヒスタミン / 血小板活性化因子 / ロイコトリエン / トロンボキサンA_2 / 即時型アレルギー反応 / 蒸留水吸入誘発気管支収縮 / 交感神経遮断薬誘発気管支収縮 / アルコール誘発気道収縮 / モルモット / ニューロペプチド / 自律神経 / 蒸留水 / 交感神経遮断薬 / アルコール誘発喘息 / 特異的気道過敏性 / c-Met遺伝子増幅 / TP53変異 / 次世代シークエンス / エルロチニブ / EGFR遺伝子変異陰性 / 小細胞肺癌 / 循環腫瘍細胞 / 血中DNA / 肺癌 Less

An image-based comprehensive evaluation of pulmonary function using deep learning
- Principal Investigator
  
  田中利恵
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Immunogenic cell death by cytotoxic agentsPrincipal Investigator
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
  Kanazawa University
Development of new method for diagnosing pulmonary function using low-dose X-ray dynamic imaging and its clinical application
- Principal Investigator
  
  Tamura Masaya
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kochi University
  Kanazawa University
Personalized therapy targeting Met gene in lung cancerPrincipal Investigator
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Establishment of diagnostic method, evaluation of pathological conditions and elucidation of refractory factors in chronic cough using exhaled breath condensate
- Principal Investigator
  
  Hara Johsuke
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Development of pulmonary function diagnosis based on low-dose X-ray imaging
- Principal Investigator
  
  Tanaka Rie
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Identification of Novel Treatment Targets and Biomarkers for Small-Cell Lung Cancer by Circulating Tumor Cell Analysis
- Principal Investigator
  
  Kimura Hideharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kanazawa University
Regulation of Topisomerase I activity by cMet in lung cancerPrincipal Investigator
- Principal Investigator
  
  Kasahara Kazuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
Analysis of predictive biomarker of Erlotinib to non-small cell lung cancer without EGFR mutation
- Principal Investigator
  
  Sone Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanazawa University
Relation cMet and Topoisomerase I in lung cancerPrincipal Investigator
- Principal Investigator
  
  KASAHARA Kazuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kanazawa University
Development of Cancer Treatment System by Induction heating
- Principal Investigator
  
  NAGANO Isamu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
Development of Cancer Treatment System by Induction Heating
- Principal Investigator
  
  NAGANO Isamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Kanazawa University
肺癌細胞のアポトーシスにおける脂質メディエーターの役割Principal Investigator
- Principal Investigator
  
  笠原寿郎
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Pathophysiology of specific bronchial hyperresponsiveness
- Principal Investigator
  
  FUJIMURA Masaki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Quantitative analysis of changes in lung density by dynamic chest radiography in association with CT values: a virtual imaging study and initial clinical corroboration2022
- Author(s)
  Sugiura Teruyo、Tanaka Rie、Samei Ehsan、Segars William Paul、Abadi Ehsan、Kasahara Kazuo、Ohkura Noriyuki、Tamura Masaya、Matsumoto Isao
- Journal Title
  
  Radiological Physics and Technology
  
  Volume: 15 Issue: 1 Pages: 45-53
- DOI
  10.1007/s12194-021-00648-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21424
[Journal Article] Two cases of chronic obstructive pulmonary disease evaluated by dynamic-ventilatory digital radiography for pulmonary function and assessment of treatment efficacy.2021
- Author(s)
  Ohkura N, Tanaka R, Hara J, Ogawa N, Abo M, Watanabe S, Tambo Y, Nishikawa S, Sone T, Kimura H, Kasahara K.
- Journal Title
  
  Respir Investig
  
  Volume: 59 Issue: 6 Pages: 871-875
- DOI
  10.1016/j.resinv.2021.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-23K21424
[Journal Article] Paradigm Shift in Respiratory Diagnosis: Current Status and Future Prospects of Dynamic Chest Radiography2021
- Author(s)
  Tanaka Rie、Kasahara Kazuo、Ohkura Noriyuki、Matsumoto Isao、Tamura Masaya、Takata Munehisa、Inoue Dai、Izumozaki Akira、Horii Junsei、Matsuura Yukihiro、Sanada Shigeru
- Journal Title
  
  Japanese Journal of Radiological Technology
  
  Volume: 77 Issue: 11 Pages: 1279-1287
- DOI
  10.6009/jjrt.2021_jsrt_77.11.1279
- NAID
  130008118963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12841
[Journal Article] Chest Dynamic-Ventilatory Digital Radiography in Chronic Obstructive or Restrictive Lung Disease.2021
- Author(s)
  Ohkura N, Tanaka R, Watanabe S, Hara J, Abo M, Nakade Y, Horii J, Matsuura Y, Inoue D, Takata M, Tamura M, Matsumoto I, Sanada S, Kasahara K.
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis.
  
  Volume: 16 Pages: 1393-1399
- DOI
  10.2147/copd.s309960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-19K12841, KAKENHI-PROJECT-20K08129, KAKENHI-PROJECT-23K21424
[Journal Article] Dynamic chest radiography: clinical validation of ventilation and perfusion metrics derived from changes in radiographic lung density compared to nuclear medicine imaging2021
- Author(s)
  Tanaka Rie、Matsumoto Isao、Tamura Masaya、Takata Munehisa、Yoshida Shuhei、Saito Daisuke、Tanaka Yusuke、Inoue Dai、Ohkura Noriyuki、Kasahara Kazuo
- Journal Title
  
  Quantitative Imaging in Medicine and Surgery
  
  Volume: 11 Issue: 9 Pages: 4016-4027
- DOI
  10.21037/qims-20-1217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12841, KAKENHI-PROJECT-20K08129, KAKENHI-PROJECT-23K21424
[Journal Article] Dynamic-ventilatory digital radiography in air flow limitation: change in lung area reflects air trapping2020
- Author(s)
  Noriyuki Ohkura, Kazuo Kasahara, Satoshi Watanabe, Johsuke Hara, Miki Abo, Takashi Sone, Hideharu Kimura, Munehisa Takata, Masaya Tamura, Isao Matsumoto, Yusuke Nakade, Shigeru Sanada, Rie Tanaka
- Journal Title
  
  Respiration
  
  Volume: Online Issue: 5 Pages: 382-388
- DOI
  10.1159/000506881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10271
[Journal Article] Real-World Efficacy of First-Line Pembrolizumab in Patients With Advanced or Recurrent Non?Small-Cell Lung Cancer and High PD-L1 Tumor Expression2020
- Author(s)
  Tambo Yuichi、Sone Takashi、Shibata Kazuhiko、Nishi Kouichi、Shirasaki Hiroki、Yoneda Taro、Araya Tomoyuki、Kase Kazumasa、Nishikawa Shingo、Kimura Hideharu、Kasahara Kazuo
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: XX Issue: 5 Pages: 1-4
- DOI
  10.1016/j.cllc.2020.02.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606, KAKENHI-PROJECT-19K07727
[Journal Article] Histopathological Type of Lung Cancer and Underlying Driver Mutations in Patients with Chronic Obstructive Pulmonary Disease (COPD) versus Patients with Asthma and COPD Overlap: A Single-Center Retrospective Study2020
- Author(s)
  Sakai T、 Hara J、Yamamura K、Abo M、Okazaki A、Ohkura N、Kasahara K
- Journal Title
  
  Turkish Thoracic Journal
  
  Volume: 21 Issue: 2 Pages: 75-79
- DOI
  10.5152/turkthoracj.2019.18100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] KEYNOTE-025: Phase 1b study of pembrolizumab in Japanese patients with previously treated programmed death ligand 1-positive advanced non-small-cell lung cancer2019
- Author(s)
  Nishio Makoto、Takahashi Toshiaki、Yoshioka Hiroshige、Nakagawa Kazuhiko、Fukuhara Tatsuro、Yamada Kazuhiko、Ichiki Masao、Tanaka Hiroshi、Seto Takashi、Sakai Hiroshi、Kasahara Kazuo、Satouchi Miyako、Han Shi Rong、Noguchi Kazuo、Shimamoto Takashi、Kato Terufumi
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 3 Pages: 1012-1020
- DOI
  10.1111/cas.13932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Osimertinib for Japanese patients with T790M‐positive advanced non‐small‐cell lung cancer: A pooled subgroup analysis2019
- Author(s)
  Hirashima Tomonori、Satouchi Miyako、Hida Toyoaki、Nishio Makoto、Kato Terufumi、Sakai Hiroshi、Imamura Fumio、Kiura Katsuyuki、Okamoto Isamu、Kasahara Kazuo、Uchida Hirohiko、Vowler Sarah L.、Mitsudomi Tetsuya
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 9 Pages: 2884-2893
- DOI
  10.1111/cas.14120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Curative thoraco-systemic therapy plus local treatment to the brain for extensive disease-small-cell lung cancer with metastasis only to the brain2019
- Author(s)
  Shibata Kazuhiko、Iwasa Keiichi、Takanaka Tsuyoshi、Yachi Tsuyoshi、Okazaki Akihito、Shiba Yasutaka、Kasahara Kazuo
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 49 Issue: 7 Pages: 687-690
- DOI
  10.1093/jjco/hyz079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Tissue and Plasma EGFR Mutation Analysis in the FLAURA Trial: Osimertinib versus Comparator EGFR Tyrosine Kinase Inhibitor as First-Line Treatment in Patients with EGFR-Mutated Advanced Non?Small Cell Lung Cancer2019
- Author(s)
  Gray J E.、Okamoto I、Sriuranpong V、Vansteenkiste J、Imamura F、Lee J S、Pang YK、Cobo Ml、Kasahara K、Cheng Y、Nogami Ni、Cho E K、Su W C、Zhang Gi、Huang X、Li-Sucholeiki X、Lentrichia B、Dearden S、Jenkins S、Saggese Matilde、Rukazenkov Yuri、Ramalingam Suresh S.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 25 Issue: 22 Pages: 6644-6652
- DOI
  10.1158/1078-0432.ccr-19-1126
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Lung segmentation based on a deep learning approach for dynamic chest radiography2019
- Author(s)
  Yuki Kitahara, Rie Tanaka, Holger R. Roth, Hirohisa Oda, Kensaku Mori, Kazuo Kasahara, Isao Matsumoto
- Journal Title
  
  Proc. SPIE 10950, Medical Imaging 2019: Computer-aided diagnosis
  
  Volume: 109503M Pages: 1-7
- DOI
  10.1117/12.2512711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10271, KAKENHI-PUBLICLY-17H05286
[Journal Article] A case of EGFR mutation-positive lung adenocarcinoma in which the T790M allele fraction was increased by repeated EGFR-TKI treatment.2019
- Author(s)
  Kimura H, Amino Y, Koba H, Tambo Y, Ohkura N, Hara J, Sone T, Kasahara K.
- Journal Title
  
  Cancer Commun (Lond).
  
  Volume: 39 Issue: 1 Pages: 67-67
- DOI
  10.1186/s40880-019-0413-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07727, KAKENHI-PROJECT-17K09606
[Journal Article] Computerized Evaluation of the Rib Kinetics and Pulmonary Function based on the Rib and Diaphragm motion by Dynamic Chest Radiography2019
- Author(s)
  Rie Tanaka, Kazuo Kasahara, Isao Matsumoto, Shigeru Sanada
- Journal Title
  
  Proceedings of the 5th international symposium on the project “Multidisciplinary computational anatomy”
  
  Volume: - Pages: 141-145
- Data Source
  KAKENHI-PROJECT-16K10271
[Journal Article] Real-World Evidence of Safety and Efficacy of Carboplatin plus Nanoparticle Albumin-Bound Paclitaxel in Patients with Advanced Non-Small-Cell Lung Cancer and Preexisting Interstitial Lung Disease: A Retrospective Study.2019
- Author(s)
  Araya T, Kita T, Ueda T, Terada N, Sakai T, Yamamura K, Kurokawa K, Uchida Y, Sone T, Kimura H, Kasahara K
- Journal Title
  
  Canadian Respiratory Journal
  
  Volume: Mar Pages: 1-7
- DOI
  10.1155/2019/5315903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] High ratio of T790M to EGFR activating mutations correlate with the osimertinib response in non-small-cell lung cancer2018
- Author(s)
  Ariyasu Ryo、Nishikawa Shingo、Uchibori Ken、Oh-hara Tomoko、Yoshizawa Takahiro、Dotsu Yosuke、Koyama Junji、Saiki Masafumi、Sonoda Tomoaki、Kitazono Satoru、Yanagitani Noriko、Horiike Atsushi、Inase Naohiko、Kasahara Kazuo、Nishio Makoto、Katayama Ryohei
- Journal Title
  
  Lung Cancer
  
  Volume: 117 Pages: 1-6
- DOI
  10.1016/j.lungcan.2017.12.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606, KAKENHI-PROJECT-16H04715, KAKENHI-PLANNED-17H06327
[Journal Article] Lung cancer in connective tissue disease-associated interstitial lung disease: clinical features and impact on outcomes2018
- Author(s)
  Watanabe Satoshi、Saeki Keigo、Waseda Yuko、Murata Akari、Takato Hazuki、Ichikawa Yukari、Yasui Masahide、Kimura Hideharu、Hamaguchi Yasuhito、Matsushita Takashi、Yamada Kazunori、Kawano Mitsuhiro、Furuichi Kengo、Wada Takashi、Kasahara Kazuo
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 10 Issue: 2 Pages: 799-807
- DOI
  10.21037/jtd.2017.12.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Role of prostaglandin E 2 in bronchoconstriction-triggered cough response in guinea pigs2018
- Author(s)
  Okazaki Akihito、Hara Johsuke、Ohkura Noriyuki、Fujimura Masaki、Sakai Tamami、Abo Miki、Katayama Nobuyuki、Kasahara Kazuo、Nakao Shinji
- Journal Title
  
  Pulm Pharmacol Ther
  
  Volume: 48 Pages: 62-70
- DOI
  10.1016/j.pupt.2017.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606, KAKENHI-PROJECT-17H01886
[Journal Article] Role of prostaglandin I2 in the bronchoconstriction-triggered cough response in guinea pigs2018
- Author(s)
  Sakai Tamami、Hara Johsuke、Yamamura Kenta、Okazaki Akihito、Ohkura Noriyuki、Sone Takashi、Kimura Hideharu、Abo Miki、Yoshimura Kenichi、Fujimura Masaki、Kasahara Kazuo、Nakao Shinji
- Journal Title
  
  Experimental Lung Research
  
  Volume: 44 Issue: 10 Pages: 455-463
- DOI
  10.1080/01902148.2019.1590883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Selective gene amplification to detect the T790M mutation in plasma from patients with advanced non-small cell lung cancer (NSCLC) who have developed epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance2018
- Author(s)
  Shingo Nishikawa, Hideharu Kimura, Hayato Koba, Taro Yoneda, Satoshi Watanabe, Tamami Sakai, Johsuke Hara, Takashi Sone, Kazuo Kasahara, Shinji Nakao
- Journal Title
  
  Journal of Thoracic Disease
  
  Volume: 10 Issue: 3 Pages: 1431-1439
- DOI
  10.21037/jtd.2018.01.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Remission of psoriasis with nintedanib for the treatment of idiopathic pulmonary fibrosis2018
- Author(s)
  Murata Akari、Watanabe Satoshi、Ikawa Yuka、Saeki Keigo、Yamamura Kenta、Matsuoka Hiroki、Tanimura Kota、Tambo Yuichi、Kasahara Kazuo
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 46 Issue: 4
- DOI
  10.1111/1346-8138.14641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09606
[Journal Article] Imatinib ameliorates bronchiolitis obliterans via inhibition of fibrocyte migration and differentiation.2017
- Author(s)
  1.4.Watanabe S, Kasahara K, Waseda Y, Takato H, Nishikawa S, Yoneda T, Hara J, Sone T, Abo M, Kimura H, Nakao S.
- Journal Title
  
  J Heart Lung Transplant.
  
  Volume: 36 Issue: 2 Pages: 138-147
- DOI
  10.1016/j.healun.2016.06.001
- NAID
  120005983030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Severe pneumonitis after nivolumab treatment in a patient with melanoma.2016
- Author(s)
  1.5.Watanabe S, Kimura H, Takato H, Waseda Y, Hara J, Sone T, Abo M, Maeda S, Matsushita T,Kasahara K.
- Journal Title
  
  Allergol Int.
  
  Volume: 65 Issue: 4 Pages: 487-489
- DOI
  10.1016/j.alit.2016.04.009
- NAID
  130005431308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Paradoxical reaction to antituberculosis therapy after 6 months of treatment for pulmonary tuberculosis: A case report.2016
- Author(s)
  Okazaki A, Watanabe S, Yoneda T, Hara J, Nishitsuji M, Nishi K, Kasahara K.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 22 Issue: 11 Pages: 748-751
- DOI
  10.1016/j.jiac.2016.03.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] A case of gingival cancer with pulmonary metastases that developed complete atrioventricular block and ventricular fibrillation as a result of myocardial metastases.2016
- Author(s)
  Yoneda T, Kase K2, Amino Y, Ogawa N, Watanabe S, Hara J, Abo M, Sone T, Kimura H, Kasahara K
- Journal Title
  
  Clin Case Rep.
  
  Volume: 10 Issue: 12 Pages: 1075-1081
- DOI
  10.1002/ccr3.695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] Phase II study of erlotinib plus tivantinib (ARQ 197) in patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer just after progression on EGFR-TKI, gefitinib or erlotinib.2016
- Author(s)
  Azuma K, Hirashima T, Yamamoto N, Okamoto I, Takahashi T, Nishio M, Hirata T, Kubota K, Kasahara K, Hida T, Yoshioka H, Nakanishi K, Akinaga S, Nishio K, Mitsudomi T, Nakagawa K.
- Journal Title
  
  ESMO Open.
  
  Volume: 1 Issue: 4 Pages: 1-6
- DOI
  10.1136/esmoopen-2016-000063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] 1.1.A Rapid and Sensitive Method for Detection of the T790M Mutation of EGFR in Plasma DNA.2016
- Author(s)
  Kimura H, Nishikawa S, Koba H, Yoneda T, Sone T, Kasahara K.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 924 Pages: 171-174
- DOI
  10.1007/978-3-319-42044-8_31
- ISBN
  9783319420424, 9783319420448
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142, KAKENHI-PROJECT-26430159
[Journal Article] Postoperative Recurrence of Invasive Thymoma with Cold Agglutinin Disease and Autoimmune Hemolytic Anemia2016
- Author(s)
  1.3.Yoneda T, Koba H, Tanimura K, Ogawa N, Watanabe S, Hara J, Abo M, Sone T, Kimura H, Kasahara K.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 18 Pages: 2685-2689
- DOI
  10.2169/internalmedicine.55.6654
- NAID
  130005414857
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430142
[Journal Article] Imatinib for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  1.1.Watanabe S, Waseda Y, Kimura H, Takato H, Ohata K, Kondo Y, Kasahara K, Nakao S.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 50 Issue: 9 Pages: 1250-1252
- DOI
  10.1038/bmt.2015.120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142, KAKENHI-PROJECT-26430159
[Journal Article] Pleuroparenchymal fibroelastosis: Distinct pulmonary physiological features in nine patients2015
- Author(s)
  Watanabe, S. Waseda, Y. Takato, H. Matsunuma, R. Johkoh, T. Egashira, R. Kawabata, Y. Ikeda, H. Yasui, M. Fujimura, M. Kasahara, K.
- Journal Title
  
  Respir Investig
  
  Volume: 53 Issue: 4 Pages: 149-155
- DOI
  10.1016/j.resinv.2015.02.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] (18)F-Fdg Uptake Predicts Diagnostic Yield of Transbronchial Biopsy in Peripheral Lung Cancer.2014
- Author(s)
  6.Umeda, Y., Y. Demura, M. Anzai, H. Matsuoka, T. Araya, M. Nishitsuji, K. Nishi, T. Tsuchida, Y. Sumida, M. Morikawa, S. Ameshima, T. Ishizaki, K. Kasahara, and T. Ishizuka.
- Journal Title
  
  Lung Cancer
  
  Volume: 85 Issue: 1 Pages: 47-52
- DOI
  10.1016/j.lungcan.2014.03.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] Efficacy and Safety of Weekly Nab-Paclitaxel Plus Carboplatin in Patients with Advanced Non-Small Cell Lung Cancer."2014
- Author(s)
  5.Satouchi, M., I. Okamoto, H. Sakai, N. Yamamoto, Y. Ichinose, H. Ohmatsu, N. Nogami, K. Takeda, T. Mitsudomi, K. Kasahara, and S. Negoro.
- Journal Title
  
  Lung Cancer
  
  Volume: 81 Issue: 2 Pages: 97-101
- DOI
  10.1089/jpm.2013.0448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430159
[Journal Article] Detection of EGFR T790M Mutation in Pericardial Effusion from a Non-Small Cell Lung Cancer Patient with Erlotinib Therapy.2013
- Author(s)
  Sakai A, Kasahara K, Sone T.
- Journal Title
  
  Case Report in Oncology
  
  Volume: 6 Issue: 1 Pages: 15-20
- DOI
  10.1159/000345947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501306
[Journal Article] Transformation to small-cell lung cancer following treatment with EGFR tyrosine kinase inhibitors in a patient with lung adenocarcinoma2013
- Author(s)
  Watanabe S, Sone T, Matsui T, Yamamura K, Tani M, Okazaki A, Kurokawa K, Tambo Y, Takato H, Ohkura N, Waseda Y, Katayama N, Kasahara K
- Journal Title
  
  Lung Cancer
  
  Volume: 82, 2 Issue: 2 Pages: 370-372
- DOI
  10.1016/j.lungcan.2013.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501306
[Journal Article] Antitumor effects of inductive hyperthermia using magnetic ferucarbotran nanoparticles on human lung cancer xenografts in nude mice.2013
- Author(s)
  Araya T, Kasahara K, Nishikawa S, Kimura H, Sone T, Nagae H, Ikehata Y, Nagano I, Fujimura M.
- Journal Title
  
  Onco Targets and Therapy
  
  Volume: 6 Pages: 237-242
- DOI
  10.2147/ott.s42815
- NAID
  120005821070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501306
[Journal Article] MET increases the sensitivity of gefitinib-resistant cells to SN-38, an active metabolite of irinotecan, by up-regulating the topoisomerase I activity2012
- Author(s)
  Asao Sakai、Kazuo Kasahara、Takashi Sone
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501306
[Journal Article] MET increases the sensitivity of gefitinib-resistant cells to SN-38, an active metabolite of irinotecan, by up-regulating the topoisomerase I activity.2012
- Author(s)
  Sakai A, Kasahara K, Ohmori T, Kimura H, Sone T, Fujimura M, Nakao S.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Issue: 9 Pages: 1337-1344
- DOI
  10.1097/jto.0b013e31825cca4c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501306
[Patent] 放射線画像解析装置及び放射線画像解析システム2018
- Inventor(s)
  村岡慎太郎，笠原寿郎，松本勲，田中利恵，他3名
- Industrial Property Rights Holder
  コニカミノルタ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-084693
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Respiratory Phase Analysis of Dynamic Chest Radiographs for Facilitating Image-based Pulmonary Function Diagnosis2022
- Author(s)
  Rentaro Tanimoto，Rie Tanaka，Hiroyuki Okamoto, Junsei Horii, Yukihiro Matsuura , Noriyuki Ohkura, Kazuo Kasahara, Masaya Tamura, Munehisa Takata, Isao Matsumoto
- Organizer
  1st International conference of radiological physics and technology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21424
[Presentation] 胸部X線動態撮影のCOPD診療における可能性2021
- Author(s)
  田中利恵，笠原寿郎，大倉徳幸
- Organizer
  第61回日本呼吸器学会学術講演会（東京国際フォーラム）
- Invited
- Data Source
  KAKENHI-PROJECT-23K21424
[Presentation] 画像診断の常識を変えるX線動態画像　X線動態画像技術の概要2020
- Author(s)
  田中利恵，笠原寿郎，松本勲，田村昌也，大倉徳幸，谷徹，新田哲久，田畑貴久，真田茂
- Organizer
  第30回日本心血管画像動態学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] 胸部X線動画像を対象とした肺野濃度計測による肺機能評価の初期検討2019
- Author(s)
  前川真里奈，田中利恵，笠原寿郎，大倉徳幸，松本勲，田村昌也，Holger Roth , 小田鉱久 , 森健策
- Organizer
  （公社）日本放射線技術学会　第12回中部放射線医療技術学術大会（CCRT）
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] 画像診断の常識を変えるX線動態画像　X線動態画像技術の概要2019
- Author(s)
  田中利恵，笠原寿郎，松本勲，田村昌也，大倉徳幸，谷徹，新田哲久，田畑貴久，真田茂
- Organizer
  第52回日本整形外科学会　骨・軟部腫瘍学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] 心胸郭比の呼吸性変化にもとづく慢性閉塞肺疾患の重症度評価：初期検討2019
- Author(s)
  藤井優妃，田中利恵，笠原寿郎，大倉徳幸，松本勲，田村昌也
- Organizer
  第12回中部放射線医療技術学術大会（CCRT）
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Assessment of health status in COPD using dynamic chest radiographs: the change ratio in lung area due to respiratory motion reflects CAT score2019
- Author(s)
  Noriyuki Ohkura, Kazuo Kasahara, Masaya Tamura, Isao Matsumoto, Shigeru Sanada, Rie Tanaka
- Organizer
  American Thoracic Society (ATS2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] 胸部X線動画像を対象とした肺野面積計測による肺機能評価の初期検討2019
- Author(s)
  和田美奈子，田中利恵，笠原寿郎，大倉徳幸，松本勲，田村昌也，Holger Roth , 小田鉱久 , 森健策
- Organizer
  （公社）日本放射線技術学会　第12回中部放射線医療技術学術大会（CCRT）
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] FPDによる新しい胸部動態検査法2019
- Author(s)
  田中利恵，笠原寿郎，松本勲，田村昌也，大倉徳幸，谷徹，新田哲久，田畑貴久，真田茂
- Organizer
  第11回呼吸機能イメージング研究会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Pulmonary Function Diagnosis with Dynamic Chest Radiography: a Computer-based Virtual Clinical Study2019
- Author(s)
  Rie Tanaka, Ehsan Samei, William Paul Segars, Ehsan Abadi, Kazuo Kasahara, Isao Matsumoto, Masaya Tamura, Noriyuki Ohkura, Junsei Horii, Yukihiro Matsuura
- Organizer
  第75回日本放射線技術学会総会学術大会
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Lung segmentation based on a deep learning approach for dynamic chest radiography2019
- Author(s)
  Yuki Kitahara, Rie Tanaka, Holger R. Roth, Hirohisa Oda, Kensaku Mori, Kazuo Kasahara, Isao Matsumoto
- Organizer
  International society for optics and photonics (SPIE), Medical imaging 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] 胸部X線動画像を対象とした深層学習による肺野セグメンテーション2018
- Author(s)
  北原侑季，田中利恵，Roth Holger，小田紘久，森健作，笠原寿朗，松本勲
- Organizer
  放射線技術科学教育系　第8回全国大学交流夏季研修会
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Next-generation sequencing analysis identifies genomic alterations in pathological morphologies  a case report of pulmonary carcinosarcoma harboring EGFR mutations.2016
- Author(s)
  Hayato Koba, Hideharu Kimura, Shingo Nishikawa, Yuichi Tambo, Takashi Sone, Atsushi Tajima,  Kazuo Kasahara
- Organizer
  ESMO ASIA 2016
- Place of Presentation
  シンガポール
- Year and Date
  2016-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142
[Presentation] MET過剰発現細胞ではtopoisomerase-I 蛋白発現が亢進する2016
- Author(s)
  米田太郎　木場隼人　西川晋吾　曽根　崇　木村英晴　笠原寿郎
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-26430159
[Presentation] Fundamentals of dynamic chest radiography: Low-cost and high performance functional imaging2016
- Author(s)
  Rie Tanaka, Shigeru Sanada, Kazuo Kasahara, Isao Matsumoto, Keita Sakuta, Yasushi Kishitani
- Organizer
  RSNA 102nd Scientific Assembly and Annual Meeting
- Place of Presentation
  McCormik Place, Chicago, IL, USA
- Year and Date
  2016-11-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10271
[Presentation] Non-invasive analysis for T790M mutations of EGFR using a selective amplification method2015
- Author(s)
  Shingo Nishikawa, Hideharu Kimura, Hayato Koba, Taro Yoneda, Takashi Sone, Chris Booth, Andrew Webb, Kazuo Kasahara
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430142
[Presentation] Prognostic impact of cMet/phosphor-Met and Topoisomerase I in small cell lung cancer2012
- Author(s)
  Hideko Ikeda、Kazuo Kasahara, Koji Kurokawa, et al
- Organizer
  5^<th> Asia Pacific Lung Cancer Conference
- Place of Presentation
  ヒルトン福岡シーホーク(福岡県)
- Data Source
  KAKENHI-PROJECT-23501306
[Presentation] Prognostic impact　of c-Met/phospho-Met and　Topoisomerase I in small cell lung cancer2012
- Author(s)
  Hideko Ikeda, Kazuo Kasahara, Koji Kurokawa, Asao Sakai, Shingo Nishikawa, Yuichi Tanbo, Tomoyuki Araya, Takashi Sone, Jyunya Fukuoka
- Organizer
  5th Asia Pacific Lung Cancer Conference
- Place of Presentation
  ヒルトン福岡シーホークホテル(福岡県）
- Data Source
  KAKENHI-PROJECT-23501306
[Presentation] Prognostic impact of cMet/phosphor-Met and Topoisomerase I in small cell lung cancer2012
- Author(s)
  池田栄子、笠原寿郎、黒川浩二、ほか
- Organizer
  第50回日本癌治療学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-23501306
[Presentation] Prognostic impact　of c-Met/phospho-Met and　Topoisomerase I in small cell lung cancer2012
- Author(s)
  池田栄子　笠原寿郎　黒川浩二　酒井麻夫　西川晋吾　丹保祐一　新屋智之　曽根崇　福岡順也　藤村政樹　中尾眞二
- Organizer
  日本癌治療学会
- Place of Presentation
  パシフィコ横浜（神奈川県)
- Data Source
  KAKENHI-PROJECT-23501306
[Presentation] Phase II study of erlotinib plus tivantinib in patients with EGFR-mutation–positive NSCLC who failed in immediately previous EGFR-TKI therapy
- Author(s)
  Tomonori Hirashima, Koichi Azuma, Nobuyuki Yamamoto, Toshiaki Takahashi, Makoto Nishio, Taizo Hirata, Kaoru Kubota, Kazuo Kasahara, Toyoaki Hida, Hiroshige Yoshioka, Kohei Suzuki, Shiro Akinaga, Kazuto Nishio, Tetsuya Mitsudomi, Kazuhiko Nakagawa
- Organizer
  2014 ASCO Annual Meeting
- Place of Presentation
  Mccormick Place Chicago,USA
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26430159
[Presentation] Retrospective analysis of prognostic factors in non-small cell lung cancer with EGFR mutations.
- Author(s)
  Shingo Nishikawa, Takashi Sone, Taro Yoneda, Kazuhiko Shibata, Koji Kurokawa, Toshiyuki Kita, Hiroki Shirasaki, Kazuyoshi Watanabe, Hideharu Kimura, Kazuo Kasahara
- Organizer
  2014 ASCO Annual Meeting
- Place of Presentation
  Mccormick Place Chicago,USA
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26430159

1. Kimura Hideharu (40444202)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. Sone Takashi (30420334)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
3. Tanaka Rie (40361985)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
4. 松本勲 (80361989)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
5. FUJIMURA Masaki (90190066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAGANO Isamu (50019775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAGITANI Satoshi (30251937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAZAWA Kenji (80018887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 大倉徳幸 (80397215)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. YASUI Masahide (60239746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ODA Makoto (50224241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUI Osamu (10019961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWAKAMI Kazuyuki (00293358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KATAYAMA Kanji (30204431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. WADA Shigehito (50303219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Hara Johsuke (30710199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. Tamura Masaya (10397185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 石浦嘉久 (60293338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 和泉自泰 (70622166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 阿保未来 (70733864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 竹村博文 (20242521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 真田茂 (50020029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 井上大 (00645129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

kasahara kazuo 笠原 寿郎

KASAHARA Kazuo 笠原 寿郎

KASAHARA Toshio 笠原 寿郎

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Immunogenic cell death by cytotoxic agentsPrincipal Investigator

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Personalized therapy targeting Met gene in lung cancerPrincipal Investigator

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Regulation of Topisomerase I activity by cMet in lung cancerPrincipal Investigator

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Relation cMet and Topoisomerase I in lung cancerPrincipal Investigator

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肺癌細胞のアポトーシスにおける脂質メディエーターの役割Principal Investigator

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kasahara kazuo 笠原寿郎

KASAHARA Kazuo 笠原寿郎

KASAHARA Toshio 笠原寿郎