Adachi Makoto 足立誠

… Alternative Names

Researcher Number	30335244
Other IDs
Affiliation (Current)	2021: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2020: 京都大学, 医学研究科, 助教 2018: 京都大学, 大学院医学研究科, 助教 2011 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2012: 京都大学, 大学院・医学研究科, 助教 2009: 京都大学, 大学院・医学研究科, 助手 … More
Review Section/Research Field	Principal Investigator General medical chemistry / Cell biology / Cell biology Except Principal Investigator Biological Sciences / Pathological medical chemistry
Keywords	Principal Investigator 細胞内シグナル伝達 / 細胞質分裂 / 極性形成 / 上皮細胞 / タイトジャンクション / 細胞増殖 / aPKC / ホスファターゼ / 極性 / キナーゼ … More Except Principal Investigator タイトジャンクション / クローディン / 上皮細胞 / 細胞間接着 / ZO-1 / 細胞接着 / アドヘレンスジャンクション / ERM / がん / ERM蛋白質 / メルリン / オクルディン / 上皮間バリアー / ノックアウトマウス / ZO-2 / ノックアウト / 血液脳関門 / PDZドメイン / cell-cell adhesion / tight junction / claudin / occludin / epidermal barrier / knockout mouse / 血管内皮細胞 / 腸管バリア / 近位尿細管 / ユビキチン化 / マーリン / アドへレンスジャンクション / トリセルリン / 細胞増殖 / Snail / 上皮間葉転換 / 転移浸潤 / GFP / ドラッグデリバリー / MUPP1 / 大腸癌 / ラディキシン / α-カテニン / β-カテニン / カドヘリン / ERM proteins / cell proliferation / コンパートメント / 内皮細胞 / バリアー / 血管 / Zo-1 / 裏打ち蛋白質 / blood-brain barrier / compartment / 上皮バリア / TJ-アピカル複合体 / アピカル細胞骨格 Less

Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriersOngoing
- Principal Investigator
  
  月田早智子
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Elucidation of novel signaling mechanisms that regulates cell proliferation and divisionPrincipal Investigator
- Principal Investigator
  
  ADACHI Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Analysis of novel signaling pathways that regulate mammalian cell cytokinesisPrincipal Investigator
- Principal Investigator
  
  adachi makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Analysis of a novel signaling network that regulates cell growth and divisionPrincipal Investigator
- Principal Investigator
  
  ADACHI Makoto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Functional analysis of novel components that localize to cell-cell adhesive structures in epithelial cellsPrincipal Investigator
- Principal Investigator
  
  ADACHI Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Molecular mechanisms of cell-cell adhesion in cancer cells
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
  Kyoto University
上皮細胞の極性形成に関与するaPKCの生理的基質の探索Principal Investigator
- Principal Investigator
  
  足立誠
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Claudins in the epithelium/endothelium barrier dysfucrition
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Molecular mechanism for cell-cell adhesion in canceration and metastasis
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY

All 2014 2013 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.2014
- Author(s)
  Makoto Adachi, Asami Kawasaki, Hisashi Nojima, Eisuke Nishida and Sachiko Tsukita
- Journal Title
  
  Genes Cells.
  
  Volume: 19 Pages: 803-20
- DOI
  10.1111/gtc.12179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460362, KAKENHI-PROJECT-25870251, KAKENHI-PLANNED-24113002, KAKENHI-PROJECT-24247037
[Journal Article] Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos2013
- Author(s)
  Hirate Y, Hirahara S, Inoue K-i, Suzuki A, Alarcon VB, Akimoto K, Hirai T, Hara T, Adachi M, Chida K, Ohno S, Marikawa Y, Nakao K, Shimono A, Sasaki H
- Journal Title
  
  Curr Biol.
  
  Volume: 23 Pages: 1181-1194
- DOI
  10.1016/j.cub.2013.05.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21116003, KAKENHI-PLANNED-21116004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23247036, KAKENHI-PROJECT-25440112, KAKENHI-PROJECT-25460362
[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight-Junction Proteins2009
- Author(s)
  Adachi, M., Hamazaki,Y., Kobayashi, Y., Itoh, M., Tsukita, S., Furuse
- Journal Title
  
  Mol. Cell. Biol 29
  
  Pages: 2372-2389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770168
[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight Junction Proteins2009
- Author(s)
  Adachi, et al.
- Journal Title
  
  Mol Cell Biol 29(昨年度報告書で印刷中と記載したもの)
  
  Pages: 2372-2389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Similar and distinct properties of MUPP1 and PaTJ, two homologous PDZ domain-containing tight-junction proteins.2009
- Author(s)
  Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S.
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 2372-2389
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] IAGAP3 regulates cell proliferation through the Ras/ERK signalling cascade2008
- Author(s)
  Nojima, H., Adachi, M., Masui, T., Okawa, K., Tsukita, S., Tsukita, S.
- Journal Title
  
  Nat. Cell Biol. 10
  
  Pages: 971-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770168
[Journal Article] Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning2008
- Author(s)
  Matsuda, M., Kobayash, Y., Masuda, S., Adachi, M., Watanabe, T., Yamashita, J. K., Nishi, E., Tsukita, S., Furuse, M.
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 939-949
- NAID
  120001384679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770168
[Journal Article] IQGAP3 regulates cell proliferation through Ras-ERK signaling cascade2008
- Author(s)
  Nojima, H., Adachi, M., Matsui, T., Okawa, K., Tsukita, S. and Tsukita
- Journal Title
  
  Nat. Cell Biol 10
  
  Pages: 971-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770168
[Journal Article] Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.2008
- Author(s)
  Matsuda M, Kobayashi Y, Masuda S, Adachi M, Watanabe T, Yamashita JK, Nishi E, Tsukita S, Furuse M.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 939-949
- NAID
  120001384679
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/PaTJ and their endogenous properties.2007
- Author(s)
  Sugihara-Mizuno Y, Adachi M, Kobayashi Y, Hamazaki Y, Nishimura M, Imai T, Furuse M, Tsukita S.
- Journal Title
  
  Genes Cells 12
  
  Pages: 473-486
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.2006
- Author(s)
  Adachi, M.
- Journal Title
  
  Mol Cell Biol. 26
  
  Pages: 9003-9015
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.2006
- Author(s)
  Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S.
- Journal Title
  
  Mol Cell Biol 26
  
  Pages: 9003-9015
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight Junction Proteins
- Author(s)
  Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S
- Journal Title
  
  Mol Cell Biol (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Polarity-dependent distribution of angiomotin localizes Hipposignaling in preimplantation embryos
- Author(s)
  Hirate, Y., Hirahara, S., Inoue, K., Suzuki, A., Alarcon, V.B., Akimoto, K., Hirai, T., Hara, T., Adachi, M., Chida, K., Ohno, M., Marikawa, Y.,Nakao, K., Shimono, A. and Sasaki, H
- Journal Title
  
  Curr. Biol
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23790331
[Presentation] 哺乳類細胞における細胞質分裂へのIQGAPファミリー分子の関与2013
- Author(s)
  足立　誠
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場1号館1階
- Data Source
  KAKENHI-PROJECT-25460362
[Presentation] Fluorescence localization-based expression cloning (FL-REX)法によるアドヘレンスジャンクション局在GTPase activating proteinの同定2007
- Author(s)
  小林由佳、松田美穂、増田小百合、足立誠、月田承一郎、古瀬幹夫
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクションに局在する2つの類似したPDZドメイン含有分子MUPPlとPatjの解析2007
- Author(s)
  足立誠
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19770168
[Presentation] タイトジャンクションに局在する2つの類似したPDZドメイン含有分子MUPP1とPatjの解析2007
- Author(s)
  足立誠
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19770168
[Presentation] タイトジャンクションに局在する2つの類似したPDZドメイン含有分子MUPP1とPatjの解析.2007
- Author(s)
  足立誠、浜崎洋子、小林由佳、月田早智子、古瀬幹夫、月田承一郎
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Overlapping and distinct functions of two jomologous, PDZ domain-containing tight junction proteins, MUPP-1 and Patj.2006
- Author(s)
  Adachi, M, Hamazaki Y, Kobayashi Y, Itoh M, Sasaki H, Takai Y, Furuse M, Tsukita S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014044

1. FURUSE Mikio (90281089)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. TSUKITA Sachiko (00188517)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. KUBO Akiharu (70335256)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TAMURA Atsushi (00362525)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SASAKI Hiroyuki (60170693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. TSUKITA Shoichiro (50155347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ODA Yukako (70452498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中尾和貴 (20217657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 伊藤雅彦 (70270486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 米村重信 (60192811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 永渕昭良 (80218023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中村駿 (80882779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 鈴木貴 (40114516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 後藤慎平 (50747219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 矢野智樹 (20546121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 田中啓雄 (70795905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 入江克雅 (20415087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SASAKI Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 佐々木洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 鈴木厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 大野茂男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 平手良和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 河嵜麻実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Adachi Makoto 足立 誠

ADACHI Makoto 足立 誠

Research Projects

Research Products

Co-Researchers

Novel approach focusing on the tight junction-based paracellular barrier combined with the apical barrier toward understanding and manipulating epithelial barriersOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of novel signaling mechanisms that regulates cell proliferation and divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of novel signaling pathways that regulate mammalian cell cytokinesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of a novel signaling network that regulates cell growth and divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of novel components that localize to cell-cell adhesive structures in epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of cell-cell adhesion in cancer cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

上皮細胞の極性形成に関与するaPKCの生理的基質の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Claudins in the epithelium/endothelium barrier dysfucrition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism for cell-cell adhesion in canceration and metastasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight-Junction Proteins2009

Author(s)

Journal Title

Data Source

[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight Junction Proteins2009

Author(s)

Journal Title

Data Source

[Journal Article] Similar and distinct properties of MUPP1 and PaTJ, two homologous PDZ domain-containing tight-junction proteins.2009

Author(s)

Journal Title

Adachi Makoto 足立誠

ADACHI Makoto 足立誠