Kubo Akiharu 久保亮治

… Alternative Names

KUBO Akiharu 久保亮治

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Researcher Number	70335256
Other IDs	https://orcid.org/0000-0003-0902-3586
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 神戸大学, 医学研究科, 教授 2016 – 2023: 慶應義塾大学, 医学部(信濃町), 准教授 2016: 慶應義塾大学, 医学部, 准教授 2015 – 2016: 慶應義塾大学, 医学部, 専任講師 2012 – 2015: 慶應義塾大学, 医学部, 講師 … More 2010 – 2012: 慶應義塾大学, 医学部, 特任講師 2008 – 2010: Keio University, 医学部, 講師 2009: 京都大学, 大学院・医学研究科, 助手 2007: Keio University, 医学部, 助教 2006: 慶応義塾大学, 医学部, 助手 2006: 慶應義塾大学, 医学部, 助手 2002 – 2005: KYOTO UNIVERSITY, FACULTY OF MEDICINE ASSISTANT, 医学研究科, 助手 2004: Kyoto University, Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / General medical chemistry / Transformative Research Areas, Section (III) / General medical chemistry Except Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / Respiratory organ internal medicine / Pathological medical chemistry / Biological Sciences
Keywords	Principal Investigator 皮膚バリア / アトピー性皮膚炎 / タイトジャンクション / 角質バリア / 中心体 / 細胞競合 / 微小管 / クローン性増殖 / 汗孔角化症 / アレルギー … More / 角質 / ランゲルハンス細胞 / 繊毛形成 / 基底小体 / エピゲノム変異 / モザイク疾患 / コレステロール生合成 / 原因遺伝子 / セカンドヒット変異 / 苔癬型免疫反応 / コレステロール / メバロン酸経路 / 前癌状態 / 皮膚炎 / クローディン1 / クローディン１ / かゆみ / 単層上皮細胞 / 重層上皮細胞 / 表皮角化 / 上皮組織 / ターンオーバー / 各層 / 発生・分化 / 免疫学 / 遺伝子 / 表皮恒常性 / ケルビン１４面体 / 表皮 / 形と機能 / 組織恒常性 / 皮膚バリア機能 / 角層バリア / バリア破綻 / セラミド / 飛行時間型質量分析顕微鏡 / 質量分析 / イメージング / 皮膚生理・生物学 / 皮膚病退学 / 経皮免疫 / 抗原感作 / 皮膚バリア解析 / 皮膚バリア機構 / タイトジャンクションバリア / aurora A kinase / Aurora A kinase / Bowen病 / 扁平上皮癌 / 繊毛 / 細胞生物学 / Centriolar satellites / PCM-1 … More Except Principal Investigator ZO-1 / クローディン / タイトジャンクション / occludin / claudin / tight junction / 血液脳関門 / ノックアウトマウス / オクルディン / 免疫寛容 / 細胞間接着 / 上皮細胞 / NSDHL / コレステロール合成 / CHILD症候群 / ケブネル現象 / blood-brain barrier / 皮膚 / 血管 / バリアー / knockout mouse / epidermal barrier / cell-cell adhesion / PDZドメイン / ノックアウト / ドラッグデリバリー / ZO-2 / 上皮間バリアー / 皮膚バリア / ゲノム解析 / ゲノムシーケンシング / 遺伝性角化症 / 皮膚遺伝学 / アトピー性皮膚炎 / デスモグレイン / 樹状細胞 / モデルマウス / 自己免疫 / メルリン / ERM蛋白質 / がん / ERM / アドヘレンスジャンクション / 細胞接着 / 悪性黒色種 / 脂漏性角化症 / 表皮 / 表皮母斑 / 汗孔角化症 / 細胞競合 / ケラチノサイト / CD1a / 乾癬様皮膚炎 / コレステロール代謝物 / CHILD症候群モデルマウス / 乾癬様皮疹 / 皮膚炎 / 菌叢解析 / Th17 / 動物モデル / 好酸球 / 気道過敏性 / 気管支喘息 / IL-23 / 経皮感作 / 免疫寛容の誘導 / コレステロール代謝 / compartment / 裏打ち蛋白質 / Zo-1 / 内皮細胞 / コンパートメント / drug delivery / peptide / barrier / CNS / 脳腫瘍 / クローディアン / ペプチド / cell proliferation / ERM proteins / カドヘリン / β-カテニン / α-カテニン / ラディキシン / 大腸癌 / MUPP1 / GFP / 転移浸潤 / 上皮間葉転換 / Snail / 細胞増殖 / フィラグリン / 細胞・組織 / ヒト毛包再生 / 再生医学 / 上皮―間葉系相互作用 / 上皮ー間葉系相互作用 / 分化誘導 / ヒトiPS細胞 / 毛包再生 / ターゲットリシーケンシング / エキソーム / エクソーム / 経皮免疫 / ランゲルハンス細胞 / 皮膚免疫 / 免役寛容 / 気管支炎 / 乾癬 / Interface Dermatitis / 天疱瘡 / 皮膚免疫学 / 自己免疫性疾患 / 皮膚診断学 / 皮膚科学 / トリセルリン / アドへレンスジャンクション / マーリン / ユビキチン化 / 近位尿細管 / 腸管バリア / 血管内皮細胞 Less

一次繊毛のエピゲノム制御に着目した悪性黒色腫のBRAF阻害剤耐性獲得機序の解明
- Principal Investigator
  
  福本毅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kobe University
Establishment of a novel disease concept for cell competitive mosaicism in humanPrincipal Investigator
- Principal Investigator
  
  久保亮治
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kobe University
Understanding the mechanism of cell competition and clonal expansion in porokeratosis to develop novel therapeuticsPrincipal Investigator
- Principal Investigator
  
  久保亮治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kobe University
Pathophysiology of porokeratosis and cell competition in humanPrincipal Investigator
- Principal Investigator
  
  Kubo Akiharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kobe University
  Keio University
細胞競合の概念に基づいた皮膚モザイク疾患の病態形成メカニズムの理解
- Principal Investigator
  
  藤田春美
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Keio University
Mechanism of lipid antigen presentation via CD1a and induction of skin inflammation
- Principal Investigator
  
  Arao Noriko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tokyo Women's Medical University
  Keio University
To Establish a treatment method for the Nagashima-type palmoplantar keratosis based on the fine analysis of genome variation and skin microbiota
- Principal Investigator
  
  SHIOHAMA Aiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Mechanism of Koebner phenomenon in CHILD syndrome
- Principal Investigator
  
  Umegaki Noriko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Molecular mechanisms of the itch sensation and skin inflammation induced by epidermal tight junction barrier deficiencyPrincipal Investigator
- Principal Investigator
  
  Kubo Akiharu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Molecular mechanisms for the epidermal barrier homeostasisPrincipal Investigator
- Principal Investigator
  
  Kubo Akiharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
The elucidation of the Nagashima-type palmoplantar keratosis caused by SERPINB7 protease inhibitor deficiency
- Principal Investigator
  
  SHIOHAMA Aiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Clarification of the pathogenesis of atopic disease by using filaggrin deficient mice in dry environment
- Principal Investigator
  
  Kawasaki Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Induction of tolerance in the airways by extracellular ATP
- Principal Investigator
  
  Suzuki Yusuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kitasato University
  Keio University
Elucidation of the role of IL-23 in bronchial asthma caused by skin barrier dysfunction and drug discovery application
- Principal Investigator
  
  Kagawa Shizuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University
Attempt to regenerate hair follicles using human iPS cell-derived epithelial and mesenchymal cells optimized for trichogenicity
- Principal Investigator
  
  Ohyama Manabu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Kyorin University
  Keio University
Evaluation of the tight junction barrier impairment in the pathogenesis of atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  KUBO Akiharu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
ランゲルハンス細胞が誘導する経皮液性免応答の制御機構
- Principal Investigator
  
  永尾圭介
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Identification of novel atopic dermatitis candidate genes with sequencing analysis against skin barrier associated 200 genes.
- Principal Investigator
  
  SASAKI Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of the visualization method of the stratum corneum barrier function by Time-of-Flight Secondary Ion Mass Spectroscopy (TOF-SIMS)Principal Investigator
- Principal Investigator
  
  KUBO Akiharu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Analysis of the dynamic skin immune and physical barrier system by tight junctions and Langerhans cellsPrincipal Investigator
- Principal Investigator
  
  KUBO Akiharu
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Clarification of the molecular and cellular mechanisms of central and peripheral tolerance to pemphigus autoantigen
- Principal Investigator
  
  AMAGAI Masayuki
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Development of new objective methods to assess disease activity in pemphigus using monoclonal single-chain- variable-fragment antibodies
- Principal Investigator
  
  ISHII Ken
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
The analysis of centrosome replication cycle in Bowen's diseasePrincipal Investigator
- Principal Investigator
  
  KUBO Akiharu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
繊毛形成における中心子複製機構および繊毛形成機構の解析Principal Investigator
- Principal Investigator
  
  久保亮治
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Keio University
Molecular mechanisms of cell-cell adhesion in cancer cells
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
  Kyoto University
新規非膜系オルガネラcentriolar satellitesの構造・機能解析Principal Investigator
- Principal Investigator
  
  久保亮治
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
新規非膜系オルガネラcentriolar satellitesの構造・機能解析Principal Investigator
- Principal Investigator
  
  久保亮治
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Claudins in the epithelium/endothelium barrier dysfucrition
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Regulation of the tight junction barrier by synthetic peptides: Towards the development of a new drug delivery method
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Molecular mechanism for cell-cell adhesion in canceration and metastasis
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY

[Book] "Molecular Dermatology : Methods and Protocols", 3D visualization of epidermal Langerhans cells. Methods Mol Biol (961) (doi:10.1007/978-1-62703-227-8_5)2013
- Author(s)
  Kubo A, Nagao K, Amagai M
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] 角化症の遺伝学的モザイク2024
- Author(s)
  久保亮治
- Journal Title
  
  皮膚科
  
  Volume: 4 Pages: 138-145
- Data Source
  KAKENHI-PROJECT-23K27622
[Journal Article] Gene-specific somatic epigenetic mosaicism of FDFT1 underlies a non-hereditary localized form of porokeratosis2024
- Author(s)
  Saito S, Saito Y, Sato S, Aoki S, Fujita H, Ito Y, Ono N, Funakoshi T, Kawai T, Suzuki H, Sasaki T, Tanaka T, Inoie M, Hata K, Kataoka K, Kosaki K, Amagai M, Nakabayashi K, Kubo A
- Journal Title
  
  American Journal of Human Genetics
  
  Volume: 111 Issue: 5 Pages: 896-912
- DOI
  10.1016/j.ajhg.2024.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27622
[Journal Article] こどもによくみられる遺伝性皮膚疾患2023
- Author(s)
  小野紀子，久保亮治
- Journal Title
  
  MB Derma
  
  Volume: 334 Pages: 93-103
- Data Source
  KAKENHI-PROJECT-23K27622
[Journal Article] Superimposition of checkerboard distribution of ephelides and neurofibromas in a patient with segmental neurofibromatosis2022
- Author(s)
  Iriki Hisato、Umegaki-Arao Noriko、Kakuta Risa、Fujita Harumi、Aoki Satomi、Amagai Masayuki、Sasaki Takashi、Hamamoto Yasuo、Nakayama Robert、Kubo Akiharu
- Journal Title
  
  JAAD Case Reports
  
  Volume: 25 Pages: 89-92
- DOI
  10.1016/j.jdcr.2022.05.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08310
[Journal Article] Palmar whitish change after water exposure in a familial mild case of loricrin keratoderma (loricrin ichthyosis)2022
- Author(s)
  Saito Sonoko、Tanaka Ryo、Ono Noriko、Umegaki‐Arao Noriko、Sasaki Takashi、Aoki Satomi、Amagai Masayuki、Kubo Akiharu
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 49 Issue: 11
- DOI
  10.1111/1346-8138.16481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08310
[Journal Article] Linear and disseminated porokeratosis in one family showing identical and independent second hits in <i>MVD</i> among skin lesions, respectively: a proof‐of‐concept study2021
- Author(s)
  Shiiya C.、Aoki S.、Nakabayashi K.、Hata K.、Amagai M.、Kubo A.
- Journal Title
  
  British Journal of Dermatology
  
  Volume: 184 Issue: 6 Pages: 1209-1212
- DOI
  10.1111/bjd.19824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03704
[Journal Article] Eosinophilic pustular folliculitis with palmoplantar lesions and nail deformity2020
- Author(s)
  Umegaki‐Arao Noriko、Tanemoto Sae、Tanese Keiji、Kubo Akiharu、Takahashi Hayato、Kurihara Yuichi、Yanagisawa Erika、Kameyama Kaori、Amagai Masayuki、Saito Masataka
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Issue: 10
- DOI
  10.1111/1346-8138.15503
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08310
[Journal Article] Successful treatment with secukinumab of three psoriatic patients undergoing dialysis2019
- Author(s)
  Mukai Miho、Kurihara Yuichi、Ito Yoshihiro、Shintani Yuka、Takahashi Hayato、Kubo Akiharu、Amagai Masayuki、Umegaki‐Arao Noriko
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 47 Issue: 1
- DOI
  10.1111/1346-8138.15132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08310
[Journal Article] A nonepidermolytic keratinocytic epidermal naevus associated with a postzygotic mutation in the gene encoding epidermal growth factor receptor2019
- Author(s)
  Umegaki‐Arao N.、Ono N.、Tanaka R.、Sasaki T.、Fujita H.、Shiohama A.、Aoki S.、Amagai M.、Kubo A.
- Journal Title
  
  British Journal of Dermatology
  
  Volume: - Issue: 5 Pages: 1303-1305
- DOI
  10.1111/bjd.18729
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10252, KAKENHI-PROJECT-18K08310
[Journal Article] Clonal Expansion of Second-Hit Cells with Somatic Recombinations or C>T Transitions Form Porokeratosis in MVD or MVK Mutant Heterozygotes2019
- Author(s)
  Kubo Akiharu、Sasaki Takashi、Suzuki Hisato、Shiohama Aiko、Aoki Satomi、Sato Showbu、Fujita Harumi、Ono Noriko、Umegaki-Arao Noriko、Kawai Tomoko、Nakabayashi Kazuhiko、Hata Kenichiro、Yamada Daisuke、Matsubara Yoichi、Kosaki Kenjiro、Amagai Masayuki
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 139 Issue: 12 Pages: 2458-2466.e9
- DOI
  10.1016/j.jid.2019.05.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08310, KAKENHI-PROJECT-17K10252
[Journal Article] Unique clinical and serological features of bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitors2018
- Author(s)
  Horikawa H.、Kurihara Y.、Funakoshi T.、Umegaki-Arao N.、Takahashi H.、Kubo A.、Tanikawa A.、Kodani N.、Minami Y.、Meguro S.、Itoh H.、Izumi K.、Nishie W.、Shimizu H.、Amagai M.、Yamagami J.
- Journal Title
  
  British Journal of Dermatology
  
  Volume: * Issue: 6 Pages: 1462-1463
- DOI
  10.1111/bjd.16479
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] A familial case of nail patella syndrome with a heterozygous in-frame indel mutation in the LIM domain of LMX1B2018
- Author(s)
  Mukai Miho、Fujita Harumi、Umegaki-Arao Noriko、Sasaki Takashi、Yasuda-Sekiguchi Fumiyo、Isojima Tsuyoshi、Kitanaka Sachiko、Amagai Masayuki、Kubo Akiharu
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 90 Issue: 1 Pages: 90-93
- DOI
  10.1016/j.jdermsci.2017.12.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07887, KAKENHI-PROJECT-16K09985, KAKENHI-PROJECT-15K09782
[Journal Article] Three cases of Nagashima-type palmoplantar keratosis associated with atopic dermatitis: A diagnostic pitfall2017
- Author(s)
  Yamauchi Aiko、Kubo Akiharu、Ono Noriko、Shiohama Aiko、Tsuruta Daisuke、Fukai Kazuyoshi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 45 Issue: 5
- DOI
  10.1111/1346-8138.14152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10252
[Journal Article] Distinct phenotype of epidermolysis bullosa simplex with infantile migratory circinate erythema due to frameshift mutations in the V2 domain of KRT5.2017
- Author(s)
  Kumagai Y, Umegaki-Arao N, Sasaki T, Nakamura Y, Takahashi H, Ashida A, Tsunemi Y, Kawashima M, Shimizu A, Ishiko A, Nakamura K, Tsuchihashi H, Amagai M, Kubo A.
- Journal Title
  
  J Eur Acad Dermatol Venereol.
  
  Volume: May;31(5) Issue: 5
- DOI
  10.1111/jdv.14005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Somatic HRAS p.G12S mosaic mutation causes unilaterally distributed epidermal nevi, woolly hair and palmoplantar keratosis2017
- Author(s)
  Honda Aki、Umegaki-Arao Noriko、Sasaki Takashi、Nakabayashi Kazuhiko、Hata Kenichiro、Matsubara Yoichi、Tanikawa Akiko、Amagai Masayuki、Kubo Akiharu
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 44 Issue: 6
- DOI
  10.1111/1346-8138.13801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Inflammatory Linear Verrucous Epidermal Nevus with a Postzygotic GJA1 Mutation Is a?Mosaic Erythrokeratodermia Variabilis et?Progressiva2017
- Author(s)
  Umegaki-Arao Noriko、Sasaki Takashi、Fujita Harumi、Aoki Satomi、Kameyama Kaori、Amagai Masayuki、Seishima Mariko、Kubo Akiharu
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 137 Issue: 4 Pages: 967-970
- DOI
  10.1016/j.jid.2016.11.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Novel nonsense mutation in SERPINB7 and the treatment of foot odor in a patient with Nagashima-type palmoplantar keratosis.2017
- Author(s)
  Katsuno M, Shiohama A, Aoki S, Kitamura H, Sasaki T, Amagai M, Kubo A.
- Journal Title
  
  J Dermatol.
  
  Volume: - Issue: 7
- DOI
  10.1111/1346-8138.13880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461701
[Journal Article] Multiple Primary Acral Lentiginous Melanoma on the Feet Developing in Lesions of Nagashima-type Palmoplantar Keratoderma.2017
- Author(s)
  Adachi A, Komine M, Maekawa T, Murata S, Shiohama A, Kubo A, Ohtsuki M.
- Journal Title
  
  Acta Derm Venereol.
  
  Volume: - Issue: 6 Pages: 756-758
- DOI
  10.2340/00015555-2640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461701
[Journal Article] Inflammatory Linear Verrucous Epidermal Nevus with a Postzygotic GJA1 Mutation Is a Mosaic Erythrokeratodermia Variabilis et Progressiva.2017
- Author(s)
  Umegaki-Arao N, Sasaki T, Fujita H, Aoki S, Kameyama K, Amagai M, Seishima M, Kubo A.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: Apr;137(4) Pages: 967-970
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Case of dominant dystrophic epidermolysis bullosa with amniotic band syndrome.2017
- Author(s)
  Sakiyama T, Umegaki-Arao N, Sasaki T, Kosaki K, Amagai M, Kubo A.
- Journal Title
  
  J Dermatol
  
  Volume: Jan;44(1) Issue: 1 Pages: 102-103
- DOI
  10.1111/1346-8138.13449
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Identification of factors contributing to phenotypic divergence via quantitative image analyses of autosomal recessive woolly hair/hypotrichosis with homozygous c.736T>A LIPH mutation.2017
- Author(s)
  Kinoshita-Ise M, Kubo A, Sasaki T, Umegaki-Arao N, Amagai M, Ohyama M.
- Journal Title
  
  Br J Dermatol.
  
  Volume: Jan;176(1) Issue: 1 Pages: 138-144
- DOI
  10.1111/bjd.14836
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Identification and Characterization of a Recessive Missense Mutation p.P277L in SERPINB7 in Nagashima-Type Palmoplantar Keratosis2016
- Author(s)
  A.Shiohama, T.Sasaki, S.Sato, J.Sakabe, T.Ito, H.Isoda, Y.Zenke, T.Nakano, T.Maeda, A.Ishiko, K.Kabashima, Y.Tokura, Y.Mitsuhashi, M.Amagai, A.Kubo
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 136 Issue: 1 Pages: 325-328
- DOI
  10.1038/jid.2015.347
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461701
[Journal Article] Novel frame-shift mutation in SERPINB7 in a Japanese patient with Nagashima-type palmoplantar keratosis.2016
- Author(s)
  Nakajima K, Ishiguro M, Shiohama A, Kubo A, Sano S.
- Journal Title
  
  J Dermatol.
  
  Volume: - Issue: 7 Pages: 841-843
- DOI
  10.1111/1346-8138.13556
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461701, KAKENHI-PROJECT-15K09769
[Journal Article] Case of lymphoplasmacytic plaque in children: Analysis of the distribution of infiltrating immune cells.2016
- Author(s)
  Mukai M, Tanese K, Umegaki-Arao N, Kubo A, Takahashi H, Amagai M.
- Journal Title
  
  J Dermatol.
  
  Volume: Nov;43(11) Issue: 11 Pages: 1368-1370
- DOI
  10.1111/1346-8138.13413
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Journal Article] Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape2016
- Author(s)
  Yokouchi M, Atsugi T, Logtestijn MV, Tanaka RJ, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A
- Journal Title
  
  Elife
  
  Volume: 5
- DOI
  10.7554/elife.19593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043, KAKENHI-PROJECT-26293259, KAKENHI-PROJECT-15K15422, KAKENHI-PROJECT-16K07066
[Journal Article] Epidermal tight junction barrier function is altered by skin inflammation, but not by filaggrin-deficient stratum corneum.2015
- Author(s)
  Yokouchi M, Kubo A, Kawasaki H, Yoshida K, Ishii K, Furuse M, Amagai M.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 77 Issue: 1 Pages: 28-36
- DOI
  10.1016/j.jdermsci.2014.11.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670507, KAKENHI-PROJECT-26293259
[Journal Article] Distinct behavior of human Langerhans cells and inflammatory dendritic epidermal cells at tight junctions in patients with atopic dermatitis2014
- Author(s)
  Yoshida K, Kubo A, Fujita H, Yokouchi M, Ishii K, Kawasaki H, Nomura T, Shimizu H, Kouyama K, Ebihara T, Nagao K, Amagai M.
- Journal Title
  
  The Journal of Allergy and Clinical Immunology
  
  Volume: 134(4) Issue: 4 Pages: 856-864
- DOI
  10.1016/j.jaci.2014.08.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-25670507, KAKENHI-PROJECT-26293259, KAKENHI-PROJECT-26893260
[Journal Article] Mutations in SERPINB7, Encoding a Member of the Serine Protease Inhibitor Superfamily, Cause Nagashima-type Palmoplantar Keratosis2013
- Author(s)
  Kubo A, Shiohama A, Sasaki T, Nakabayashi K, Kawasaki H, Atsugi T, Sato S, Shimizu A, Mikami S, Tanizaki H, Uchiyama M, Maeda T, Ito T, Sakabe J, Heike T, Okuyama T, Kosaki R, Kosaki K, Kudoh J, Hata K, Umezawa A, Tokura Y, Ishiko A, Niizeki H, Kabashima K, Mitsuhashi Y, Amagai M
- Journal Title
  
  Am J Hum Genet
  
  Volume: 93 Issue: 5 Pages: 945-956
- DOI
  10.1016/j.ajhg.2013.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044, KAKENHI-PUBLICLY-25129706
[Journal Article] The stratum corneum comprises three layers with distinct metal-ion barrier properties2013
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Nagao K, Ohashi Y, Amagai M
- Journal Title
  
  Sci. Rep
  
  Volume: 3 Issue: 1 Pages: 1731-1731
- DOI
  10.1038/srep01731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-23659555, KAKENHI-PROJECT-25670507
[Journal Article] The stratum corneum comprises three layers with distinct metal-ion barrier properties2013
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Nagao K, Ohashi Y, and Amagai M
- Journal Title
  
  Sci Rep
  
  Volume: 3 Pages: 1731-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659555
[Journal Article] Functional tight junction barrier localizes in the second layer of the stratum granulosum of human epidermis2013
- Author(s)
  Yoshida K, Yokouchi M, Nagao K, Ishii K, Amagai M, Kubo A
- Journal Title
  
  J Dermatol Sci
  
  Volume: 71 Issue: 2 Pages: 89-99
- DOI
  10.1016/j.jdermsci.2013.04.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-23591628, KAKENHI-PROJECT-25670507
[Journal Article] A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis2013
- Author(s)
  Sasaki T, Shiohama A, Kubo A, Kawasaki H, Ishida-Yamamoto A, Yamada T, Hachiya T, Shimizu A, Okano H, Kudoh J, Amagai M
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 132 Issue: 5 Pages: 1111-1120
- DOI
  10.1016/j.jaci.2013.08.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-24591620
[Journal Article] 3D visualization of epidermal langerhans cells2013
- Author(s)
  Kubo, A.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 961 Pages: 119-127
- DOI
  10.1007/978-1-62703-227-8_5
- ISBN
  9781627032261, 9781627032278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-25670507
[Journal Article] Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma2013
- Author(s)
  Kubo A, Oura Y, Hirano T, Aoyama Y, Sato S, Nakamura K, Takae Y, and Amagai M
- Journal Title
  
  J Dermatol
  
  Volume: 40 Issue: 7 Pages: 553-557
- DOI
  10.1111/1346-8138.12185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin2012
- Author(s)
  Nagao K, Kobayashi T, Moro K, Ohyama M, Adachi T, Kitashima DY, Ueha S, Horiuchi K, Tanizaki H, Kabashima K, Kubo A, Cho YH, Clausen BE, Matsushima K, Suematsu M, Furtado GC, Lira SA, Farber JM, Udey MC, Amagai M
- Journal Title
  
  Nat Immunol
  
  Volume: 13(8) Pages: 744-752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014
[Journal Article] Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases2012
- Author(s)
  Kubo A, Nagao K, Amagai M
- Journal Title
  
  J Clin Invest
  
  Volume: 122(2) Issue: 2 Pages: 440-447
- DOI
  10.1172/jci57416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044
[Journal Article] Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin2012
- Author(s)
  Sandilands A,Brown SJ, Goh CS, Pohler E, Wilson NJ, Campbell LE, Miyamoto K, Kubo A, Irvine AD, Thawer-Esmail F, Munro CS, McLean WH, Kudoh J, Amagai M, Matsui T
- Journal Title
  
  J. Invest. Dermatol
  
  Volume: 132 Issue: 5 Pages: 1507-10
- DOI
  10.1038/jid.2011.479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790267, KAKENHI-PROJECT-22249044
[Journal Article] Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.2012
- Author(s)
  Keisuke Nagao
- Journal Title
  
  Nature Immunology
  
  Volume: 13(8) Issue: 8 Pages: 744-752
- DOI
  10.1038/ni.2353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08120, KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-22390095, KAKENHI-PROJECT-23790432, KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-24659373, KAKENHI-PUBLICLY-23118526
[Journal Article] Skin barrier disruption : a requirement for allergen sensitization?2012
- Author(s)
  De Benedetto A, Kubo A, Beck LA
- Journal Title
  
  J Invest Dermatol
  
  Volume: 132 Issue: 3 Pages: 949-963
- DOI
  10.1038/jid.2011.435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice2012
- Author(s)
  Kawasaki H
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: (Epub) Issue: 6 Pages: 1538-1546
- DOI
  10.1016/j.jaci.2012.01.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-23390086
[Journal Article] Dynamic cooperation between epidermal barriers and Langerhans cells2011
- Author(s)
  Kubo A
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 34 Issue: 2 Pages: 76-84
- DOI
  10.2177/jsci.34.76
- NAID
  10029431898
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome2011
- Author(s)
  Ouchi T
- Journal Title
  
  J Exp Med
  
  Volume: 208 Issue: 13 Pages: 2607-2613
- DOI
  10.1084/jem.20111718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-22590437
[Journal Article] SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing2011
- Author(s)
  Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Tanahashi S, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M
- Journal Title
  
  EMBO Mol. Med
  
  Volume: 3 Issue: 6 Pages: 320-333
- DOI
  10.1002/emmm.201100140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790267, KAKENHI-PROJECT-22249044, KAKENHI-PROJECT-23390325
[Journal Article] 未来皮膚科学:Molecular Barriology of the Skin2010
- Author(s)
  久保亮治
- Journal Title
  
  日本皮膚科学会雑誌
  
  Volume: 120 Pages: 2521-2523
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] ランゲルハンス細胞による外来抗原捕捉機構2010
- Author(s)
  久保亮治
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 40 Pages: 267-270
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] 皮膚バリア研究の新展開2010
- Author(s)
  久保亮治
- Journal Title
  
  フレグランスジャーナル
  
  Volume: 5 Pages: 14-18
- Data Source
  KAKENHI-PROJECT-22249044
[Journal Article] External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers.2009
- Author(s)
  Kubo A, et al.
- Journal Title
  
  J Exp.Med. 206
  
  Pages: 2937-2946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] Periungual squamous cell carcinoma induced by human papillomavirus type 59 in an immunosuppressed patient2009
- Author(s)
  Tanese K, Akiyoshi A, Saito M, Kubo A, Takanashi M, Ishiko A
- Journal Title
  
  J. Am. Acad. Dermatol 61
  
  Pages: 167-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers2009
- Author(s)
  Kubo A, Nagao K, Yokouchi M, Sasaki H, Amagai M
- Journal Title
  
  J. Exp. Med 206
  
  Pages: 2937-2946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers2009
- Author(s)
  Kubo A, Nagao K, Yokouchi M, Sasaki H, Amagai M
- Journal Title
  
  J Exp Med
  
  Volume: 206(13) Issue: 13 Pages: 2937-2946
- DOI
  10.1084/jem.20091527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229014
[Journal Article] Sentan: a novel specific component of the apical structure of vertebrate motile cilia2008
- Author(s)
  Kubo A, Yuba-Kubo A, Tsukita S, Tsukita S, Amagai M
- Journal Title
  
  Mol. Biol. Cell 19
  
  Pages: 5338-5346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] PCM1 is recruited to the centrosome by the cooperativeaction of DISC1 and BBS4 and is a candidate for psychiatricillness2008
- Author(s)
  Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, Tsukita S, et al.
- Journal Title
  
  Archivos of General Psychiatry 65
  
  Pages: 996-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] Sentan : a novel specific component of the apical structure of vertebrate motile cilia2008
- Author(s)
  Kubo A, Yuba-Kubo A, Tsukita S, Tsukita S, Amagai M
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 5338-5349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591330
[Journal Article] Odf2/cenexin-deficient mother centrioles lack the distal/subdistal appendages and the ability to generate primary cilia.2005
- Author(s)
  Hiroaki Ishikawa, Akiharu Kubo, Shoichiro Tsukita, Sachiko Tsukita
- Journal Title
  
  Nature Cell Biology (in press)
- Data Source
  KAKENHI-PROJECT-16790165
[Journal Article] Gene-knockout analysis of two γ-tubulin isoforms in mice.2005
- Author(s)
  Akiko Yuba-Kubo, Akiharu Kubo, Masaki Hata, Shoichiro Tsukita
- Journal Title
  
  Developmental Biology (in press)
- Data Source
  KAKENHI-PROJECT-16790165
[Journal Article] Gene-knockout analysis of two γ-tubulin isoforms in mice.2005
- Author(s)
  Akiko Yuba-Kubo, Akiharu Kubo, Masaki Hata, Shoichiro Tsukita
- Journal Title
  
  Developmental Biology 282
  
  Pages: 361-373
- Data Source
  KAKENHI-PROJECT-16790165
[Journal Article] Gene knockout analysis of two γ-tubulin isoforms in mice.2005
- Author(s)
  Yuba-Kubo et al.
- Journal Title
  
  Dev.Biol. 282
  
  Pages: 361-373
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Odf2/cenexin-deficient mother centrioles lack the distal/subdistal appendages and the ability to generate primary cilia.2005
- Author(s)
  Hiroaki Ishikawa, Akiharu Kubo, Shoichiro Tsukita, Sachiko Tsukita
- Journal Title
  
  Nature Cell Biology 7
  
  Pages: 517-524
- Data Source
  KAKENHI-PROJECT-16790165
[Presentation] 皮膚モザイク疾患から迫る多細胞生命自律性2023
- Author(s)
  久保亮治
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] スキンタッグはなぜできる？　身近な症状に潜む遺伝学的モザイク2023
- Author(s)
  久保亮治
- Organizer
  日本皮膚科学会東京支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] 遺伝子から眺める皮膚科学　~身近な疾患から稀少疾患まで~2023
- Author(s)
  久保亮治
- Organizer
  日本小児皮膚科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] 遺伝学的モザイクから考えるクローン性増殖疾患の皮膚科学2023
- Author(s)
  久保亮治
- Organizer
  日本皮膚悪性腫瘍学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] Genetic Mosaicism in the Pathogenesis of Common and Rare Skin Diseases2023
- Author(s)
  Akiharu Kubo
- Organizer
  Annual Autumn Meeting of the Korean Dermatology Association
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] 皮膚疾患・症状に見られるモザイクの考え方2023
- Author(s)
  久保亮治
- Organizer
  日本臨床皮膚科医会総会・臨床学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27622
[Presentation] A non-epidermolytic epidermal nevus associated with a postzygotic EGFR mutation.2023
- Author(s)
  Umegaki-Arao N, Ono N, Tanaka R, Sasaki T, Fujita H, Shiohama A, Amagai M, Kubo A.
- Organizer
  1st. International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08310
[Presentation] Genetic mosaicism in skin disorders2022
- Author(s)
  Akiharu Kubo
- Organizer
  The 48th Annual Meeting of the Taiwanese Dermatological Association
- Invited
- Data Source
  KAKENHI-PROJECT-20H03704
[Presentation] The genetic landscape of porokeratosis in Japan2022
- Author(s)
  Akiharu Kubo, Sonoko Saito, Satomi Aoki, Kazuhiko Nakabayashi, Hisato Suzuki, Takashi Sasaki5, Kenichiro Hata3, Kenjiro Kosaki, Masayuki Amagai
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-20H03704
[Presentation] Postnatal somatic recombinations and C>T transition mutations are two major triggers of disseminated superficial actinic porokeratosis in MVD or MVK mutant heterozygotes.2019
- Author(s)
  Kubo A, Sasaki T, Suzuki H, Shiohama A, Aoki S, Kawai T, Nakabayashi K, Hata K, Kosaki K, Amagai M.
- Organizer
  49th Annual ESDR Meeting, Bordeaux, FRANCE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10252
[Presentation] Tmem79 deficient mice sequentially develop dermatitis associated with S.aureus non-dominant and dominant dysbioses.2018
- Author(s)
  Takashi Sasaki, Aiko Shiohama, Keigo Matsuda, Takuji Yamada, Hiroshi Kawasaki, Akiharu Kubo, Masayuki Amagai
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10252
[Presentation] Three genetic variants in TLR1, TIRAP and PSAPL1 are enriched in a specific subgroup of adult atopic dermatitis showing persistent skin manifestation on the face and neck area.2018
- Author(s)
  Fumiyo Yasuda-Sekiguchi, Aiko Shiohama, Hiroshi Kawasaki, Tamotsu Ebihara, Akiharu Kubo, Masayuki Amagai, Takashi Sasaki
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10252
[Presentation] GJA1モザイク変異を同定したInflammatory linear verrucous epidermal nevusの世界第１例2017
- Author(s)
  梅垣知子、佐々木貴史、藤田春美、青木里美、亀山香織、天谷雅行、清島真理子、久保亮治
- Organizer
  第116回　日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-15K09782
[Presentation] Azathioprine-induced anagen effluvium and leukopenia associated with NUDT15 polymorphisms2017
- Author(s)
  Hisashi Nomura, Yuichi Kurihara, Masataka Saito, Jun Yamagami Takeru Funakoshi, Masayuki Amagai, Noriko Umegaki-Arao, Akiharu Kubo
- Organizer
  第10回　国際毛髪科学研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Presentation] LMX1B with an inframe indel mutation in a familial case of nail patella syndrome shows loss of its transcriptional activity2017
- Author(s)
  Miho Mukai, Harumi Fujita, Noriko Umegaki-Arao, Takashi Sasaki, Fumiyo Yasuda, Hayato Takahashi, Tsuyoshi Isojima, Sachiko Kitanaka, Masayuki Amagai, Akiharu Kubo,
- Organizer
  第42回　日本研究皮膚科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Presentation] The identification of a postzygotic GJA1 mutation in a patient with an inflammatory linear verrucous epidermal nevus suggests that the disease is a mosaic of erythrokeratodermia variabilis et progressiva2017
- Author(s)
  Noriko Umegaki-Arao, Takashi Sasaki, Harumi Fujita, Satomi Aoki, Masayuki Amagai, Mariko Seishima, Akiharu Kubo
- Organizer
  ESDR 2017 in Salzburg
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09782
[Presentation] Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  14th Meeting of the European Epidermal Barrier Research Network
- Place of Presentation
  Munchen, Germany
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Homeostasis and Dysfunction of the Epidermal Barriers2016
- Author(s)
  Kubo A
- Organizer
  12th Meeting of the German-Japanese Society of Dermatology
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県軽井沢市）
- Year and Date
  2016-10-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Cell shape determines the regulatory mechanisms for maintaining tight junction barrier homeostasis in epidermal turnover2016
- Author(s)
  Yokouchi M, Atsugi T, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A
- Organizer
  76th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Kierland, Arizona, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] claudin-1欠損マウスを用いた脂腺タイトジャンクションバリアの解析2016
- Author(s)
  厚木徹, 横内麻里子, 平林愛, 大山学, 天谷雅行, 久保亮治
- Organizer
  第23回分子皮膚フォーラム
- Place of Presentation
  ホテルグランヴィア大阪（大阪府大阪市北区）
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Spatiotemporal orchestration of epidermal cell turnover based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  CDB International Symposium “Body Surface Tactics”
- Place of Presentation
  理化学研究所多細胞システム形成研究センター（兵庫県神戸市中央区）
- Year and Date
  2016-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Spatiotemporal orchestration of epidermal cell turnover based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  CDB International Symposium “Body Surface Tactics”
- Place of Presentation
  理化学研究所多細胞システム形成研究センター（兵庫県神戸市中央区）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  14th Meeting of the European Epidermal Barrier Research Network
- Place of Presentation
  Munchen, Germany
- Year and Date
  2016-09-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Epidermal barrier homeostasis and its breakage in skin diseases2016
- Author(s)
  Kubo A
- Organizer
  10th Annual Symposium in Institute of Human-Environment Interface Biology
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2016-02-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  2nd International Symposium on ‘Autoinflammation breaks Barriers’
- Place of Presentation
  Munster, Germany
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Kubo A
- Organizer
  2nd International Symposium on ‘Autoinflammation breaks Barriers’
- Place of Presentation
  Munster, Germany
- Year and Date
  2016-11-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Epidermal barrier homeostasis and its breakage in skin diseases2016
- Author(s)
  Kubo A
- Organizer
  The 41st Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  仙台国際センター（宮城県仙台市青葉区）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Homeostasis and Dysfunction of the Epidermal Barriers2016
- Author(s)
  Kubo A
- Organizer
  12th Meeting of the German-Japanese Society of Dermatology
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県軽井沢市）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Cell shape determines the regulatory mechanisms for maintaining tight junction barrier homeostasis in epidermal turnover2016
- Author(s)
  Yokouchi M, Atsugi T, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A
- Organizer
  76th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Kierland, Arizona, USA
- Year and Date
  2016-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] 多発性子宮筋腫と皮膚平滑筋腫症を認めた Hereditary Leiomyomatosis and Renal Cell Cancerの2例2016
- Author(s)
  梅垣知子、木島俊英、小峰佑奈、伊勢美咲、舩越建、進伸幸、常深祐一郎、林伸和、白石英馨、天谷雅行、久保亮治
- Organizer
  日本皮膚科学会総会2016
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-06-03
- Data Source
  KAKENHI-PROJECT-15K09782
[Presentation] Epidermis-specific ablation of claudin-1 in adult mice demonstrates a key role of tight junction barrier in the development of atopic dermatitis2015
- Author(s)
  Kubo A, Hirano T, Kawasaki H, Yokouchi M, Atsugi T, Amagai M
- Organizer
  The 64th Meeting of Japanese Society of Allergology
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Year and Date
  2015-05-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Tight junctions, the skin barrier and atopic dermatitis2015
- Author(s)
  Kubo A
- Organizer
  23rd World Congress of Dermatology
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2015-06-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Vicious Cycle in Atopic Dermatitis: Epidermal Barriers, Allergic Sensitization and Inflammation2015
- Author(s)
  Kubo A
- Organizer
  The 44th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市白石区）
- Year and Date
  2015-11-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Functional tight junction barriers in sebaceous glands: defects in holocrine secretion in claudin-1 deficient mice.2015
- Author(s)
  Atsugi T, Yokouchi M, Hirabayashi A, Ohyama M, Amagai M, and Kubo A
- Organizer
  The 40 th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Classical cadherins control polarized organization of junctions and cytoskeleton in stratified epithelia2015
- Author(s)
  Rubsam M, Kubo A, Mertz A, Boggetti B, Goranci G, Dufresne E, Horsley V, Amagai M, and Niessen C
- Organizer
  The 40 th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Homeostatic cell turnover mechanisms that maintain tight junction barrier integrity in the epidermis2015
- Author(s)
  Yokouchi M, Kajimura M, Suematsu M, Furuse M, Amagai M, and Kubo A
- Organizer
  The 40 th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Homeostatic cell turnover mechanisms that maintain tight junction barrier integrity in the epidermis.2015
- Author(s)
  Yokouchi M, Kajimura M, Suematsu M, Furuse M, Amagai M, and Kubo A
- Organizer
  The 6th Annual Congress of Pan AsianPacific Skin Barrier Research Society PAPSBRS
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Functional tight junction barriers in sebaceous glands: defects in holocrine secretion in claudin-1 deficient mice2015
- Author(s)
  Atsugi T, Yokouchi M, Hirabayashi A, Ohyama M, Amagai M, Kubo A
- Organizer
  The 40 th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Tight junction barrier dysfunction induced by epidermis-specific claudin-1 ablation is sufficient to cause dermatitis in mice2015
- Author(s)
  Kubo A, Hirano T, Yokouchi M, Kawasaki H, Atsugi T, Amagai M
- Organizer
  75th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  アトランタ（USA）
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15422
[Presentation] Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis2014
- Author(s)
  Hirano T, Yokouchi M, Atsugi T, Amagai M, and Kubo A
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Year and Date
  2014-12-13
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Ishizaki I, Miyayama T, Sanada N, Kubo A, and Setou M2014
- Author(s)
  Ishizaki I, Miyayama T, Sanada N, Kubo A, and Setou M
- Organizer
  SISS-16 (The Scientific International Symposium on SIMS and Related Techniques Based on Ion-Solid Interactions)
- Place of Presentation
  Sapporo
- Year and Date
  2014-05-16
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis.2014
- Author(s)
  Hirano T, Yokouchi M, Atsugi T, Amagai M, and Kubo A.
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology,
- Place of Presentation
  京都
- Year and Date
  2014-12-13
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] アトピー性皮膚炎と皮膚バリア2014
- Author(s)
  久保亮治
- Organizer
  第77回日本皮膚科学会東京支部学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Tight junction barriers in the skin and skin diseases2014
- Author(s)
  Kubo A.
- Organizer
  5th Pan Asian Pacific Skin Barrier Research Annual Symposium
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Tight junction barriers in the skin and skin diseases.2014
- Author(s)
  Kubo A.
- Organizer
  5th Pan Asian Pacific Skin Barrier Research Annual Symposium
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] アトピー性皮膚炎と皮膚バリア2014
- Author(s)
  久保亮治
- Organizer
  第77回日本皮膚科学会東京支部
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 進化と疾患が教えてくれる皮膚バリア構造の「かたち」と機能2014
- Author(s)
  久保亮治
- Organizer
  第41回皮膚かたち研究学会
- Place of Presentation
  東京
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Tight junction barriers are functionally organized in hair follicles and sebaceous glands2014
- Author(s)
  Atsugi T, Yokouchi M, Ohyama M, Amagai M, Kubo A.
- Organizer
  74th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  New Mexico, USA
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 経皮感作とアレルギー疾患2014
- Author(s)
  久保亮治
- Organizer
  第16回日本褥瘡学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] Tight junction barriers are functionally organized in hair follicles and sebaceous glands.2014
- Author(s)
  Atsugi T, Yokouchi M, Ohyama M, Amagai M, and Kubo A
- Organizer
  74th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  New Mexico, USA
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] 皮膚バリアの構造と機能を可視化する～バリア破綻疾患の病態解明へのアプローチ～2014
- Author(s)
  久保亮治
- Organizer
  第14回医学生物学電子顕微鏡シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] フィラグリン欠損マウスの角層バリア機能破綻に対する乾燥環境因子の関与2014
- Author(s)
  川崎洋, 久保亮治, 平野尚茂, 山田健人, 天谷雅行
- Organizer
  第42回臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26461702
[Presentation] 進化と疾患が教えてくれる皮膚バリア構造の「かたち」と機能2014
- Author(s)
  久保亮治
- Organizer
  第41回皮膚かたち研究学会
- Place of Presentation
  東京
- Year and Date
  2014-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 角層の形成機構と先天性角層バリア破綻疾患2014
- Author(s)
  久保亮治
- Organizer
  第113回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] 角層の形成機構と先天性角層バリア破綻疾患2014
- Author(s)
  久保亮治
- Organizer
  第113回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2014-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 経皮感作とアレルギー疾患2014
- Author(s)
  久保亮治
- Organizer
  第16回日本褥瘡学会学術集会,
- Place of Presentation
  名古屋
- Year and Date
  2014-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 皮膚バリアの構造と機能を可視化する～バリア破綻疾患の病態解明へのアプローチ～2014
- Author(s)
  久保亮治
- Organizer
  第14回医学生物学電子顕微鏡シンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293259
[Presentation] The Three Musketeers of the Epidermal Barrier2013
- Author(s)
  Kubo A
- Organizer
  4th Pan Asian Pacific Skin Barrier Research Annual Symposium
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 角質層バリアと皮膚免疫2013
- Author(s)
  久保亮治
- Organizer
  第29回日本皮膚悪性腫瘍学会学術大会
- Place of Presentation
  甲府
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 皮膚タイトジャンクションバリアから見た皮膚疾患の病態と病理2013
- Author(s)
  久保亮治
- Organizer
  第１０２回日本病理学会総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Molecular Barriology of the Stratum Corneum and Epidermal Tight Junctions2013
- Author(s)
  Kubo A
- Organizer
  Molecular Mechanisms Regulating Skin Homeostasis 2013
- Place of Presentation
  Koln, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] バリア異常からみたアトピー性皮膚炎の病態と治療2013
- Author(s)
  久保亮治
- Organizer
  第１１２回日本皮膚科学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] The Three Musketeers of the Epidermal Barrier2013
- Author(s)
  Kubo A
- Organizer
  4th Pan Asian Pacific Skin Barrier Research Annual Symposium
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] バリア異常からみたアトピー性皮膚炎の病態と治療2013
- Author(s)
  久保亮治
- Organizer
  第１１２回日本皮膚科学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Molecular Barriology of the Stratum Corneum and Epidermal Tight Junctions2013
- Author(s)
  Kubo A
- Organizer
  Molecular Mechanisms Regulating Skin Homeostasis 2013
- Place of Presentation
  Koln, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 角質層バリアと皮膚免疫2013
- Author(s)
  久保亮治
- Organizer
  第29回日本皮膚悪性腫瘍学会学術大会
- Place of Presentation
  甲府
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚タイトジャンクションバリアから見た皮膚疾患の病態と病理.2013
- Author(s)
  久保亮治
- Organizer
  第１０２回日本病理学会総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] The stratum corneum comprises three layers with distinct barrier properties to metal ions.2013
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Nagao K, Ohashi Y, and Amagai M
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] The stratum corneum comprises three layers with distinct barrier properties to metal ions2013
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Nagao K, Ohashi Y, Amagai M
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] The stratum corneum comprises three layers with distinct barrier properties to metal ions2013
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Nagao K, Ohashi Y, and Amagai M
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-25670507
[Presentation] 皮膚の角化重層上皮によるバリア機構と疾患2012
- Author(s)
  久保亮治
- Organizer
  第85回日本細菌学会
- Place of Presentation
  長崎:長崎国際会議場
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Dendritic cells penetrate epidermal tight junction barriers to uptake external antigens : a possible involvement in atopic dermatitis2012
- Author(s)
  Kubo A, Yoshida K, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Nagao K, Amagai M
- Organizer
  Molecular Structure and Function of the Apical Junctional Complex in Epithelia and Endothelia 2012
- Place of Presentation
  Melida, Mexico
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Surface barrier and immunology of the skin.2012
- Author(s)
  Kubo A
- Organizer
  Surface Barrier Immunology Study Group (SBARIS) The 4th stage, 3rd meeting(招待講演)
- Place of Presentation
  大阪：千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] The stratum corneum comprises three layers with distinct barrier properties, as revealed by TOF-SIMS imaging.2012
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M
- Organizer
  62nd Montagna Symposium on the Biology of Skin 2012
- Place of Presentation
  Portland, Oregon,USA
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] 三次元イメージングで出会う皮膚銀河の天の川2012
- Author(s)
  久保亮治
- Organizer
  第111回日本皮膚科学会総会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] The stratum corneum comprises three layers with distinct barrier properties, as revealed by TOF- SIMS imaging2012
- Author(s)
  Kubo A
- Organizer
  62nd Montagna Symposium on the Biology of Skin 2012
- Place of Presentation
  Portland, Oregon
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] 3D Imaging of the Mammalian Epidermis2012
- Author(s)
  Kubo A
- Organizer
  37th Annual Meeting of the Japanese society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS Imaging reveals Multi-layered Barrier Structure of the Stratum Corneum of Skin.2012
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] The stratum corneum comprises three layers with distinct barrier properties, as revealed by TOF-SIMS imaging2012
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, Amagai M
- Organizer
  62nd Montagna Symposium on the Biology of Skin 2012
- Place of Presentation
  Portland, Oregon
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS Imaging reveals Multi-layered Barrier Structure of the Stratum Corneum of Skin2012
- Author(s)
  Kubo A
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] Dendritic cells penetrate epidermal tight junction barriers to uptake external antigens: a possible involvement in atopic dermatitis2012
- Author(s)
  Kubo A
- Organizer
  Molecular Structure and Function of the Apical Junctional Complex in Epithelia and Endothelia 2012
- Place of Presentation
  Melida, Mexico
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Surface barrier and immunology of the skin2012
- Author(s)
  Kubo A
- Organizer
  Surface Barrier Immunology Study Group (SBARIS) The 4^<th> stage, 3^<rd> meeting
- Place of Presentation
  大阪:千里阪急ホテル(招待講演)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Pros and Cons:バリア障害か炎症か：バリア障害か炎症か～バリア障害について2012
- Author(s)
  久保亮治
- Organizer
  第49回小児アレルギー学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS Imaging reveals Multi-layered Barrier Structure of the Stratum Corneum of Skin2012
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, Amagai M
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 3D Imaging of the Mammalian Epidermis2012
- Author(s)
  Kubo A
- Organizer
  37th Annual Meeting of the Japanese society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] 3D Imaging of the Mammalian Epidermis2012
- Author(s)
  Kubo A
- Organizer
  37th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] アレルギー疾患発症因子としての皮膚バリア障害2012
- Author(s)
  久保亮治
- Organizer
  第49回小児アレルギー学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] タイトジャンクションバリアと疾患2012
- Author(s)
  久保亮治
- Organizer
  第111回日本皮膚科学会総会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution time-of-flight secondary ion mass spectrometry imaging and sequential immunofluorescent analysis of multi-layered barrier structure of the mouse skin stratum corneum2011
- Author(s)
  久保亮治, 石崎逸子, 久保亜紀子, 川崎洋, 大橋善治, 天谷雅行
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道:北海道大学
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Langerhans cell dendrites penetrate through epidermal tight junction barrier during foreign antigen uptake2011
- Author(s)
  Kubo A
- Organizer
  The 70th Annual Meeting of Society for Investigative Dermatology
- Place of Presentation
  Arizona, USA
- Data Source
  KAKENHI-PROJECT-21229014
[Presentation] Investigation of the tight junction barrier in hair follicles and sebaceous glands2011
- Author(s)
  Kubo A, Yokouchi M, Atsugi T, Ohyama M, Amagai M
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚バリア機能とタイトジャンクション2011
- Author(s)
  久保亮治
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京:グランドプリンスホテル新高輪国際館パミール(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Human epidermal tight junctions are functional and allow penetration of activated Langerhans cell dendrites2011
- Author(s)
  Yoshida K, Kubo A, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Ohyama M, Nagao K, Amagai M
- Organizer
  71th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Phoenix, Arizona
- Year and Date
  2011-05-05
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Physiological and immunological barriers in the epidermis2011
- Author(s)
  Kubo A
- Organizer
  The 59th Annual Meeting of Japanese Association for Dental Research
- Place of Presentation
  広島:広島国際会議場(招待講演)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS imaging and sequential immunofluore scent analysis of multi-layered barrier structure of the mouse skin stratum corneum2011
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, Amagai M
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Denver, Colorado, USA : Denver Convention Center
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Surface barrier and immunology of the skin2011
- Author(s)
  Kubo A
- Organizer
  Keio Kanrinmaru/G-COE winter symposium 2011
- Place of Presentation
  東京:慶應義塾大学
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] TOF-SIMSによるマウス皮膚組織の深さ方向分析2011
- Author(s)
  石崎逸子, Hammond J S, Bryan S R, 久保亮治, 山本公
- Organizer
  第59回日本質量分析学会
- Place of Presentation
  大阪:ホテル阪急エキスポパーク
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Investigation of the tight junction barrier in hair follicles and sebaceous glands2011
- Author(s)
  Kubo A
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  京都:国立京都国際会館
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Investigation of the tight junction barrier in hair follicles and sebaceous glands2011
- Author(s)
  Kubo A
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-21229014
[Presentation] Impaired stratum corneum barrier and enhanced percutaneous immune responses in filaggrin knockout mice2011
- Author(s)
  Kawasaki H, Nagao K, Kubo A, Hata T, Mizuno H, Yamada T, Amagai M
- Organizer
  71th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Phoenix, Arizona, USA : JW Marriott Desert Ridge Resort & Spa
- Year and Date
  2011-05-05
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Impaired stratum corneum barrier and enhanced percutaneous immune responses in filaggrin knockout mice2011
- Author(s)
  Kawasaki H, Nagao K, Kubo A, Hata T, Mizuno H, Yamada T, Amagai M
- Organizer
  71th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Phoenix, Arizona
- Year and Date
  2011-05-05
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] TOF-SIMS Characterization of In Vivo and Transdermally Treated Mouse Skin2011
- Author(s)
  Ishizaki I, Hammond J, Bryan S, Kubo A, Yamamoto A
- Organizer
  18th International Conference on Secondary Ion Mass Spectrometry
- Place of Presentation
  Riva del Garda, Trentino, Italy : Riva del Garda Fierecongressi SpA
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS imaging and sequential immunofluorescent analysis of multi-layered barrier structure of the mouse skin stratum corneum2011
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, and Amagai M
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Denver, Colorado, USA: Denver Convention Center
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] Langerhans cells but not Langerin-negative inflammatory dendritic epidermal cells gain access to the environment outside the tight junction barrier in atopic dermatitis skin2011
- Author(s)
  Yoshida K, Kubo A, Kawasaki H, Nagao K, Amagai M
- Organizer
  2011 The annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] TOF-SIMS Characterization of In Vivo and Transdermally Treated Mouse Skin2011
- Author(s)
  Ishizaki I, Hammond J, Bryan S, Kubo A, and Yamamoto A
- Organizer
  18th International Conference on Secondary Ion Mass Spectrometry
- Place of Presentation
  Riva del Garda, Trentino, Italy: Riva del Garda Fierecongressi SpA
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] Langerin-positive Langerhans cells but not Langerin-negative inflammatory dendritic epidermal cells penetrate epidermal tight junction barriers in atopic dermatitis2011
- Author(s)
  Kubo A, Yoshida K, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Nagao K, Amagai M
- Organizer
  12th International Workshop on Langerhans Cells
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Langerin-positive Langerhans cells but not Langerin-negative inflammatory dendritic epidermal cells penetrate epidermal tight junction barriers in atopic dermatitis2011
- Author(s)
  Yoshida K, Kubo A, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Nagao K, Amagai M
- Organizer
  41st Annual Meeting of European Society for Dermatological Research
- Place of Presentation
  Barcelona, Spain : Barcelona International Convention Centre
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Physiological and immunological barriers in the epidermis2011
- Author(s)
  Kubo A
- Organizer
  The 59th Annual Meeting of Japanese Association for Dental Research(招待講演)
- Place of Presentation
  広島：広島国際会議場
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] High Resolution TOF-SIMS Imaging of the Multi-Layered Barrier Structure of Mouse Skin2011
- Author(s)
  Ishizaki I, Kubo A, Ohashi Y, Yamamoto A, Hammond J, Fisher G, Bryan S
- Organizer
  American Vaccume Society 58th International Symposimu & Exhibition
- Place of Presentation
  Nashville, Tennessee, USA: Nashville Convention Center
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] 皮膚(重層上皮)におけるタイトジャンクションバリア恒常性維持機構の解析2011
- Author(s)
  横内麻里子, 古瀬幹夫, 天谷雅行, 久保亮治
- Organizer
  第23回高遠シンポジウム
- Place of Presentation
  長野:高遠さくらホテル
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution time-of-flight secondary ion mass spectrometry imaging and sequential immunofluorescent analysis of multi-layered barrier structure of the mouse skin stratum corneum2011
- Author(s)
  久保亮治, 石崎逸子, 久保亜紀子, 川崎洋, 大橋善治, 天谷雅行
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道：北海道大学
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] Epidermal barrier dysfunction and percutaneous sensitization as an initial trigger of atopic dermatitis2011
- Author(s)
  Kubo A
- Organizer
  Asia Pacific Association of Pediatric Allergy, Respirology & Immunology 2011
- Place of Presentation
  福岡:福岡国際会議場(招待講演)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 哺乳類皮膚バリア構造の解析～物理的バリアと免疫細胞の相互作用を中心に～2011
- Author(s)
  久保亮治
- Organizer
  アトピー性皮膚炎治療研究会第16回シンポジウム
- Place of Presentation
  北九州:北九州国際会議場(招待講演)
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Langerin-positive Langerhans cells but not Langerin-negative inflammatory dendritic epidermal cells penetrate epidermal tight junction barriers in atopic dermatitis2011
- Author(s)
  Yoshida K, Kubo A, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Nagao K, Amagai M
- Organizer
  41st Annual Meeting of European Society for Dermatological Research
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High-resolution TOF-SIMS imaging and sequential immunofluorescent analysis of multi-layered barrier structure of the mouse skin stratum corneum2011
- Author(s)
  Kubo A, Ishizaki I, Kubo A, Kawasaki H, Ohashi Y, Amagai M
- Organizer
  59th ASMS Conference on Mass Spectrometry and Allied Topics
- Place of Presentation
  Denver, Colorado
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] High Resolution TOF-SIMS Imaging of the Multi-Layered Barrier Structure of Mouse Skin2011
- Author(s)
  Ishizaki I, Kubo A, Ohashi Y, Yamamoto A, Hammond J, Fisher G, Bryan S
- Organizer
  American Vaccume Society 58th International Symposimu & Exhibition
- Place of Presentation
  Nashville, Tennessee, USA : Nashville Convention Center
- Year and Date
  2011-11-01
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] TOF-SIMSによるマウス皮膚組織の深さ方向分析2011
- Author(s)
  石崎逸子, Hammond J S, Bryan S R, 久保亮治, 山本公
- Organizer
  第59回日本質量分析学会
- Place of Presentation
  大阪：ホテル阪急エキスポパーク
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] Langerin-positive Langerhans cells but not Langerin-negative inflammatory dendritic epidermal cells penetrate epidermal tight junction barriers in atopic dermatitis2011
- Author(s)
  Kubo A, Yoshida K, Yokouchi M, Ishii K, Kawasaki H, Ebihara T, Nagao K, Amagai M
- Organizer
  Langerhans Cell Meeting 2011
- Place of Presentation
  Innsbruck, Austria : Ursulinensale am Marktplatz
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Physiological and immunological barriers in the epidermis2011
- Author(s)
  Kubo A
- Organizer
  Asia Pacific Association of Pediatric Allergy, Respirology & Immunology 2011(招待講演)
- Place of Presentation
  福岡：福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23659555
[Presentation] 表皮タイトジャンクションバリア研究の現状と将来展望2011
- Author(s)
  久保亮治
- Organizer
  第150回フレグランスジャーナルセミナー
- Place of Presentation
  東京:アルカディア市ケ谷(招待講演)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers2010
- Author(s)
  久保亮治
- Organizer
  第109回日本皮膚科学会総会皆見省吾記念賞受賞記念講演
- Place of Presentation
  大阪:大阪国際会議場(招待講演)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Langerhans cell dendrites penetrate through epidermal tight junction barrier during foreign antigen uptake2010
- Author(s)
  Kubo A
- Organizer
  70th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Hilton Atlanta, Atlanta, Georgia、USA
- Year and Date
  2010-05-06
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Maintenance of intact epidermal tight junction barriers in filaggrin-deficient mouse models2010
- Author(s)
  Yokouchi M, Kubo A, Kawasaki H, Amagai M
- Organizer
  The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Wakayama, Japan
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚が隔てる外と内:皮膚バリア構造と免疫の視点から2010
- Author(s)
  久保亮治
- Organizer
  第22回高遠シンホ〓シ〓ウム
- Place of Presentation
  高遠:高遠さくらホテル(招待講演)
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚バリア研究の新展開:タイトジャンクションバリアとランゲルハンス細胞の視点から2010
- Author(s)
  久保亮治
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸:神戸国際展示場(招待講演)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Langerhans cell dendrites penetrate through epidermal tight junction barrier during foreign antigen uptake2010
- Author(s)
  Kubo A, Nagao K, Yokouchi M, Yoshida K, Sasaki H, Amagai M
- Organizer
  70th Annual Meeting Society for Investigative Dermatology
- Place of Presentation
  Atlanta, Georgia, USA
- Year and Date
  2010-05-06
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Epidermial tight junction barriers and trans-tight junction antigen uptake activity of Langerhans cells2010
- Author(s)
  Kubo A
- Organizer
  The 25th Annual Meeting of the Japanese Society for Psoriasis Research
- Place of Presentation
  山口県宇部市:宇部全日空ホテル(招待講演)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚バリア機構の新しい捉え方2010
- Author(s)
  久保亮治
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京:東京国際フォーラム(招待講演)
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Molecular Barriology of the Skin2010
- Author(s)
  久保亮治
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪:大阪国際会議場(招待講演)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] 皮膚が隔てる外と内:皮膚バリア構造2010
- Author(s)
  久保亮治
- Organizer
  奈良先端技術大学GCOEセミナー
- Place of Presentation
  奈良:奈良先端技術大学(招待講演)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22249044
[Presentation] Bowen病における中心体制御異常の検討2009
- Author(s)
  久保亮治
- Organizer
  第108回日本皮膚科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591330
[Presentation] Identification of novel ciliary proteins using microarray analyses of in vitro ciliogenesis2008
- Author(s)
  A. Kubo, A. Yuba-Kubo, Sa. Tsukita, Sh Tsukita, M. Amagai
- Organizer
  68th Annual meeting of International Investigative Dermatology 2008
- Place of Presentation
  Kyoto
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20591330
[Presentation] Sentan : A novel specific component of the apical structure of vertebrate motile cilia2008
- Author(s)
  A. Kubo, A. Yuba-Kubo, Sa. Tsukita, Sh Tsukita, M. Amagai
- Organizer
  48th annual meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco
- Year and Date
  2008-12-16
- Data Source
  KAKENHI-PROJECT-20591330
[Presentation] 細胞生物学におけるかたちへのこだわり2007
- Author(s)
  久保亮治
- Organizer
  日本皮膚科学会東部支部総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2007-09-23
- Data Source
  KAKENHI-PROJECT-18790198

1. AMAGAI Masayuki (90212563)

# of Collaborated Projects: 8 results

# of Collaborated Products: 42 results
2. FURUSE Mikio (90281089)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. SASAKI Takashi (70306843)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. 久保亜紀子 (50455573)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
5. ADACHI Makoto (30335244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. NAGAO Keisuke (40286521)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
7. SHIOHAMA Aiko (40383731)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
8. TSUKITA Shoichiro (50155347)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 福本毅 (80778770)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. Umegaki Noriko (80397629)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
11. OOYAMA Manabu (10255424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. TSUKITA Sachiko (00188517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SASAKI Hiroyuki (60170693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ISHII Ken (50296670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. Kawasaki Hiroshi (70445344)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
16. Suzuki Yusuke (80306696)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 藤田春美 (30736971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. TAMURA Atsushi (00362525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ODA Yukako (70452498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HIDEYUKI OKANO (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MATSUI Takeshi (10452442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. KUBO Akiharu (50452272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
23. Kagawa Shizuko (80645507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Fukunaga Koichi (60327517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中尾和貴 (20217657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 山上淳 (80327618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 舩越建 (80365353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 伊藤雅彦 (70270486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 米村重信 (60192811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 永渕昭良 (80218023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 高橋勇人 (40398615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 藤原進 (40645389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. Kabata Hiroki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Masaki Katsunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. Mochimaru Takao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. Matsusaka Masako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. ISOJIMA Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. NOMURA Toshifumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 清水宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Akiharu 久保 亮治

KUBO Akiharu 久保 亮治

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Establishment of a novel disease concept for cell competitive mosaicism in humanPrincipal Investigator

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Understanding the mechanism of cell competition and clonal expansion in porokeratosis to develop novel therapeuticsPrincipal Investigator

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Pathophysiology of porokeratosis and cell competition in humanPrincipal Investigator

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Molecular mechanisms of the itch sensation and skin inflammation induced by epidermal tight junction barrier deficiencyPrincipal Investigator

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Molecular mechanisms for the epidermal barrier homeostasisPrincipal Investigator

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Kubo Akiharu 久保亮治

KUBO Akiharu 久保亮治