HATTA MITSUTOKI 八田光世

… Alternative Names

八田光世ハツタミツトキ

HATTA Mitsutoki 八田光世

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Researcher Number	30344518
Other IDs
Affiliation (Current)	2025: 福岡歯科大学, 口腔歯学部, 教授
Affiliation (based on the past Project Information) *help	2024: 福岡歯科大学, 口腔歯学部, 教授 2018 – 2020: 福岡歯科大学, 口腔歯学部, 教授 2016 – 2017: 福岡歯科大学, 口腔歯学部, 准教授 2014 – 2015: 福岡歯科大学, 歯学部, 講師 2013 – 2015: 福岡歯科大学, 口腔歯学部, 講師 … More 2009 – 2011: 熊本大学, 大学院・生命科学研究部, 助教 2004: 北大, 歯学研究科(研究院), 助手 2003: 北海道大学, 大学院・歯学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Basic Section 57020:Oral pathobiological science-related / Orthodontics/Pediatric dentistry / General physiology / Metabolomics
Keywords	Principal Investigator 遺伝子発現 / エンハンサー / エピゲノム / 遺伝子発現制御 / 上皮－間葉転換 / FoxO1 / 骨芽細胞 / 骨形成・再生 / 転写因子 Except Principal Investigator LPS … More / TRPチャネル / 上皮バリア機能 / 歯周病 / 歯周病菌 / バリア機能 / 細胞増殖 / 口腔上皮 / ゲノム / 歯学 / 骨格性下顎前突症 / エクソーム解析 / 基礎ゲノム科学 / 歯科矯正学 / 3次元培養 / 表皮 / ミニジーン / エピジェネティックス / 分化 / クロライドチャネル / 上皮細胞 / スプライシング / 標的遺伝子 / GRP78 / ERストレス / β細胞 / hepatocyte nuclear factor / 転写因子 / 遺伝子 / インスリン / 糖尿病 Less

ケラチノサイトの機能を制御するエンハンサーの解明Principal Investigator
- Principal Investigator
  
  八田光世
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Fukuoka Dental College
Involvement of TRP channels in the development of periodontitis
- Principal Investigator
  
  Uchida Kunitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  University of Shizuoka
  Fukuoka Dental College
Molecular mechanisms of epithelial-mesenchymal transition in keratinocytesPrincipal Investigator
- Principal Investigator
  
  Hatta Mitsutoki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Fukuoka Dental College
Identification for susceptibility genes of mandibular pragmatism from the results of next-generation sequencing
- Principal Investigator
  
  KAJII Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Fukuoka Dental College
Molecular basis of multifunctional expression induced by the mRNA splicing selective in undifferentiated epithelium
- Principal Investigator
  
  Yamazaki Jun
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Fukuoka Dental College
Functional analysis of the pioneer transcription factor FoxO1 in keratinocytesPrincipal Investigator
- Principal Investigator
  
  HATTA MITSUTOKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Fukuoka Dental College
Molecular mechanism of type 2 diabetes based on pancreatic-cell enriched transcription factors
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
転写因子Osterixによる骨形成・再生制御に関する基礎的研究Principal Investigator
- Principal Investigator
  
  八田光世
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hokkaido University

All 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Analysis of the Influence of <i>Porphyromonas gingivalis</i> on the Human Oral Mucosa with a Three-dimensional Construct Model2020
- Author(s)
  笠孝成, 内田邦敏, 岡村和彦, 八田光世, 山﨑純, 坂上竜資
- Journal Title
  
  The Japanese Journal of Conservative Dentistry
  
  Volume: 63 Issue: 2 Pages: 144-155
- DOI
  10.11471/shikahozon.63.144
- NAID
  130007840632
- ISSN
  0387-2343, 2188-0808
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09566
[Journal Article] PLXNA2 identified as a candidate gene by genome-wide association analysis for mandibular prognathism in human chondrocytes2018
- Author(s)
  Kajii TS, Oka A, Hatta M, Yamazaki J, Yamashita J, Iida J
- Journal Title
  
  Biomedical Reports
  
  Volume: 9 Pages: 253-258
- DOI
  10.3892/br.2018.1128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11949
[Journal Article] Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.2018
- Author(s)
  Hatta M, Miyake Y, Uchida K, Yamazaki J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 496(2) Issue: 2 Pages: 381-386
- DOI
  10.1016/j.bbrc.2018.01.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11659, KAKENHI-PROJECT-26670104
[Journal Article] Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats2018
- Author(s)
  Arita S., Hatta M., Uchida K., Kita T., Okamura K., Ryu T., Murakami H., Sakagami R., Yamazaki J.
- Journal Title
  
  J. Periodont. Res.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670104
[Journal Article] TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-β1 in an in vitro wound healing model of rats2018
- Author(s)
  Ishii Taro、Uchida Kunitoshi、Hata Shozaburo、Hatta Mitsutoki、Kita Tomo、Miyake Yuki、Okamura Kazuhiko、Tamaoki Sachio、Ishikawa Hiroyuki、Yamazaki Jun
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 18 Issue: 3 Pages: 30126-30129
- DOI
  10.1016/j.jdermsci.2018.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05928, KAKENHI-PROJECT-15K11358, KAKENHI-PROJECT-26670104, KAKENHI-PROJECT-16K20662
[Journal Article] Mechanistic insight into the aberrant silencing of the keratin 13 gene in oral squamous cell carcinoma cells.2016
- Author(s)
  Hatta M., Arita S., Yamazaki J.
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 58 Issue: 2 Pages: 45-49
- DOI
  10.1016/j.job.2016.01.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670104, KAKENHI-PROJECT-25462906
[Journal Article] 3-Deazaneplanocin A suppresses aggressive phenotype-related gene expression in an oral squamous cell carcinoma cell line.2015
- Author(s)
  Hatta M., Naganuma K., Kato K., Yamazaki J.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 468(1-2) Issue: 1-2 Pages: 269-273
- DOI
  10.1016/j.bbrc.2015.10.115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670104, KAKENHI-PROJECT-25462906
[Journal Article] NF-kappaB-regulated transcriptional control of CLCA in a differentiated mouse keratinocyte line2015
- Author(s)
  Hiromatsu R., Hatta M., Okamura K., Sakagami R., Yamazaki J.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 78 Issue: 3 Pages: 189-196
- DOI
  10.1016/j.jdermsci.2015.03.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670104
[Journal Article] Voltage-gated K^+channel KCNQ1 regulates insulin secretion in MIN6-cell line2011
- Author(s)
  Yamagata K, Senokuchi T, Lu M, Takemoto M, Karim MF, Go C, Sato Y, Hatta M, Yoshizawa T, Araki E, Miyazaki J, Song W-J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 620-625
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Glucose enhances collectrin protein expression in insulin-producing MIN6 cells2009
- Author(s)
  Saisho K, Fukuhara A, Yasuda T, Sato Y, Fukui K, Iwahashi H, Imagawa A, Hatta M, Shimomura I, Yamagata K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 389 Pages: 133-137
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Anks4b, a novel target of HNF4α interacts with GRP78 and regulates endoplasmic reticulum stress-induced apoptosis in pancreaticβ-cells
- Author(s)
  Sato Y, Hatta M, Karim Fazlul, Sawa T, Wei F-W, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, Yamagata K
- Journal Title
  
  J Biol. Chem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] The role of transcription factor SNAI2 in EMT during wound healing2019
- Author(s)
  Yuki Miyake, Mitsutoki Hatta
- Organizer
  2019 TAO 32nd Annual Meeting & 8th Resident Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11659
[Presentation] Suppression of keratin 13 expression by transforming growth factor-β1-induced epithelial-mesenchymal transition in human keratinocyte HaCaT cells2018
- Author(s)
  Mitsutoki Hatta, Yuki Miyake, Kunitoshi Uchida, Jun Yamazaki
- Organizer
  第91回日本薬理学会年会/第18回国際薬理学・臨床薬理学会議 WCP2018-18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11659
[Presentation] 骨格性下顎前突症のゲノムワイド関連解析により得た感受性遺伝子PLXNA2は軟骨内骨化に関与する2018
- Author(s)
  梶井貴史、岡　晃、斉藤文男、八田光世、玉置幸雄、飯田順一郎
- Organizer
  第36回日本頭蓋顎顔面外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11949
[Presentation] 口腔粘膜上皮の構造維持に関与するペプチジルアルギニン脱イミノ化酵素2018
- Author(s)
  有田晴一、八田光世、笠孝成、内田邦敏、坂上竜資、山崎純
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] The function of PLXNA2, which was suggested to be candidate genes by genome-wide association study for mandibular prognathism, on chondrocytes2018
- Author(s)
  Kajii TS, Oka A, Iida J, Hatta M, Yamazaki J, Yamashita J, Tamaoki S
- Organizer
  11th Asian Pacific Orthodontic Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11949
[Presentation] 口腔粘膜のバリア形成に寄与するペプチジルアルギニン脱イミノ化酵素2017
- Author(s)
  有田晴一、笠　孝成、八田光世、内田邦敏、坂上竜資、山﨑　純
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] 皮膚と口腔粘膜におけるフィラグリンの発現様式および分解過程の比較2016
- Author(s)
  有田晴一、村上弘、八田光世、坂上竜資、山﨑　純
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] クロマチン修飾酵素阻害薬の口腔がん細胞の悪性形質に対する抑制効果2016
- Author(s)
  八田光世、永沼香織、有田晴一、加藤健一、大久保つや子、山﨑　純
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] 皮膚と口腔粘膜におけるフィラグリンの発現様式及び分解過程2016
- Author(s)
  有田晴一、八田光世、笠　孝成、坂上竜資、山﨑　純
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] 口腔がん細胞におけるエピジェネティックサイレンシングに対する3-deazaneplanocin Aの効果2015
- Author(s)
  八田光世、永沼香織、山﨑　純
- Organizer
  第68回日本薬理学会西南部会
- Place of Presentation
  下関
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] 3-Deazaneplanocin Aは口腔がん細胞の遺伝子発現パターンを変化させる2015
- Author(s)
  八田光世、永沼香織、有田晴一、石井太郎、大久保つや子、山﨑　純
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] マウスケラチノサイト株におけるCLCA発現のNFkappaBによる転写制御2015
- Author(s)
  廣松　亮、八田光世、坂上竜資、山﨑　純
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] 3-Deazaneplanocin Aは口腔がん細胞の遺伝子発現パターンを変化させる2015
- Author(s)
  八田　光世、永沼　香織、有田　晴一、石井　太郎、大久保　つや子、山﨑　純
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25462906
[Presentation] マウス上皮細胞株におけるClチャネル調節因子のNFkappaBによる転写制御2014
- Author(s)
  廣松　亮、八田光世、田中喜太郎、坂上竜資、山﨑　純
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学（福岡県北九州市）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] マウスケラチノサイトにおけるCLCA遺伝子の発現調節因子2014
- Author(s)
  廣松　亮、八田光世、坂上竜資、山﨑　純
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26670104
[Presentation] Analysis of a novel HNF4 target gene Anks4b in pancreaticβ-cells2011
- Author(s)
  Yoshifumi Sato, Mitsutoki Hatta, Md. Fazlul Karim, Tatsuya Yoshizawa, Kazuya Yamagata
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 膵β細胞における新規HNF-4標的遺伝子Anks4bの機能解析BMB20102010
- Author(s)
  八田光世、MD. Fazlul Karim、佐藤叔史、瀬ノ口隆文、山縣和也
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390281

1. Yamazaki Jun (50230397)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. Uchida Kunitoshi (20581135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. YAMAGATA Kazuya (70324770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. SENOKUCHI Takafumi (00530320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KATO Kenichi (90320332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KAJII Takashi (60322822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 岡村和彦 (00224056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 岡晃 (80384866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 吉住潤子 (40596376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 長岡良礼 (40868204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 武石幸容 (00758055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HATTA MITSUTOKI 八田 光世

八田 光世 ハツタ ミツトキ

HATTA Mitsutoki 八田 光世

Research Projects

Research Products

Co-Researchers

ケラチノサイトの機能を制御するエンハンサーの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of TRP channels in the development of periodontitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of epithelial-mesenchymal transition in keratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification for susceptibility genes of mandibular pragmatism from the results of next-generation sequencing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of multifunctional expression induced by the mRNA splicing selective in undifferentiated epithelium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of the pioneer transcription factor FoxO1 in keratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of type 2 diabetes based on pancreatic-cell enriched transcription factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子Osterixによる骨形成・再生制御に関する基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of the Influence of <i>Porphyromonas gingivalis</i> on the Human Oral Mucosa with a Three-dimensional Construct Model2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] PLXNA2 identified as a candidate gene by genome-wide association analysis for mandibular prognathism in human chondrocytes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Keratin 13 gene is epigenetically suppressed during transforming growth factor-β1-induced epithelial-mesenchymal transition in a human keratinocyte cell line.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats2018

Author(s)

Journal Title

Data Source

[Journal Article] TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-β1 in an in vitro wound healing model of rats2018

Author(s)

Journal Title

DOI

HATTA MITSUTOKI 八田光世

八田光世ハツタミツトキ

HATTA Mitsutoki 八田光世