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HIPPO YOSHITAKA  筆宝 義隆

… Alternative Names

Hippo Yoshitaka  筆宝 義隆

筆宝 義隆  ヒッポウ ヨシタカ

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Researcher Number 30359632
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4975-1812
Affiliation (Current) 2023: 千葉県がんセンター(研究所), 発がん制御研究部, 研究所長
2023: 国立研究開発法人国立がん研究センター, 研究所, 客員研究員
Affiliation (based on the past Project Information) *help 2014 – 2022: 千葉県がんセンター(研究所), 発がん制御研究部, 部長
2016 – 2017: 国立研究開発法人国立がん研究センター, 研究所, 客員研究員
2015: 国立研究開発法人国立がん研究センター, その他部局等, その他
2015: 国立研究開発法人国立がん研究センター, 研究所動物実験部門, 客員研究員
2014: 独立行政法人国立がん研究センター, その他部局等, 客員研究員
2005: 東大, 助手
2003 – 2004: 東京大学, 国際・産学共同研究センター, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Tumor biology / Tumor biology and related fields / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Basic Section 53010:Gastroenterology-related / Tumor biology / Applied genomics / Medical genome science / Gastroenterology … More / Human pathology / Basic Section 49030:Experimental pathology-related / Basic Section 56010:Neurosurgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related Less
Keywords
Principal Investigator
発がん / オルガノイド / モデル / 3次元培養 / 癌 / 幹細胞 / Kras / マウス / 胃癌 / ムチン … More / マイクロアレイ / モノクローナル抗体 / 腫瘍マーカー / MUC13 / WWOX / 癌抑制遺伝子 / 大腸がん / 大腸 / 膵臓癌 / 膵癌 / 子宮がん / 癌肉腫 / 転移 / Pten / 子宮体がん / 子宮内膜がん / がん肉腫 / 子宮 / 遺伝子 / 胃がん … More
Except Principal Investigator
オルガノイド / 薬剤感受性 / 癌 / 三次元培養 / 膵臓 / 3次元培養 / IPMN / 発がん / 膵がん / 卵巣がん / 患者由来がんモデル / NCYM / MYCN / 子宮体がん / 癌肉腫 / 正常肺3D培養 / in vitro肺発がんモデル / ゲノム / 転写 / コピー数多型 / タイリングアレイ / DNAメチル化 / クロマチン免疫沈降 / マイクロアレイ / ゲノムコピー数 / 染色体変異 / メチル化 / クロマチン修飾 / インスレータ / 発現プロファィル解析 / アレル別コピー数 / ChIP on Chip解析 / 臨床ゲノム学 / genome / transcription / copy number variation / tiling array / DNA methylation / Chromatin immunoprecipitation / がんゲノム / 一細胞シークエンス / 腫瘍内多様性 / 腫瘍内不均質性 / がん細胞進化 / バイオインフォマティクス / がん不均質性 / 膵癌 / 化学療法 / 粘液性腫瘍 / 膵液 / 前癌病変 / 粘液 / 膵臓粘液腫瘍 / 膵管内乳頭粘液性腫瘍 / 細胞診 / 早期診断マーカー / オルガノイドモデル / PanIN / 腺房細胞癌 / 膵腺房細胞癌 / 3次元培養 / 大腸癌 / 遺伝子変異 / monensin / glioblastoma / モネンシン / 膠芽腫 / Caspase2 / MYC / Glioblastoma / 子宮頸がん / 治療抵抗性 / 腫瘍不均一性 / 腫瘍浸潤リンパ球 / 治療標的 / 発がんモデル / 薬剤スクリーニング / がん遺伝子 / がん抑制遺伝子 / 神経芽腫 / Myc-nick / SNP / VUVCD / 分裂期チェックポイント / 分裂期崩壊 / Caspase-2 / グルカゴン遺伝子欠損マウス / 膵内分泌腫瘍 / α細胞 / グルカゴン / 遺伝子改変マウス / アミノ酸代謝 / 脂質代謝 Less
  • Research Projects

    (23 results)
  • Research Products

    (126 results)
  • Co-Researchers

    (51 People)
  •  Elucidation of the mechanisms underlying drug-resistance and development of therapeutic strategy of refractory cervical cancer using patient-derived organoids

    • Principal Investigator
      海老沢 桂子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Elucidation of the mechanisms underlying drug-resistance and development of predictive biomarker using patient-derived ovarian cancer organoids

    • Principal Investigator
      田中 尚武
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Exploration of a novel therapeutic strategy of pancreatic cancers using organoid-based carcinogenesis model

    • Principal Investigator
      泉谷 昌志
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokyo
  •  Organoid-based modeling of gastric carcinogenesis and elucidation of its mechanismPrincipal Investigator

    • Principal Investigator
      筆宝 義隆
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  NCYMによる分裂期制御機構とその神経芽腫発がんへの寄与の解明

    • Principal Investigator
      末永 雄介
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  膵内分泌腫瘍モデルマウスを用いたアミノ酸代謝異常を介した発がん機構の解明

    • Principal Investigator
      堀 美香
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Elucidation of the mechanism underlying tumorigenesis and development of therapeutic strategy for uterine carcinosarcoma using murine and patient-derived organoids

    • Principal Investigator
      鈴鹿 清美
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Elucidation of genetic interactions underlying tumor development and metastasis using murine endometrial organoids

    • Principal Investigator
      丸 喜明
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  マウスオルガノイド発癌モデルを用いた大腸癌遺伝子変異と薬剤感受性の関連性の探索

    • Principal Investigator
      落合 頼業
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Okinaka Memorial Institute for Medical Research
  •  Development of innovative treatment for glioblastoma targeting MYC family genes

    • Principal Investigator
      瀬戸口 大毅
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Research on carcinogenesis and cell differentiation using established human pancreatic acinar cell carcinoma cell line

    • Principal Investigator
      Kita Emiri
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  An integrated study using patient-derived organoids toward elucidation of biological feature and development of therapeutic strategy of ovarian cancer

    • Principal Investigator
      Tanaka Naotake
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  膵発がん早期病変を標的とした診断マーカーの新規オルガノイドモデルを用いた探索

    • Principal Investigator
      泉谷 昌志
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      The University of Tokyo
  •  Integrative research on IPMN using organoids obtained from patients' pancreatic juice.

    • Principal Investigator
      Taketo Yamaguchi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Organoid-based Modeling of Endometrial CarcinogenesisPrincipal Investigator

    • Principal Investigator
      Hippo Yoshitaka
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  New Approach for Organoid Culture in Patients with Pancreatic Tumor

    • Principal Investigator
      Kita Emiri
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Revealing cancer-cell evolution and intra-tumor heterogeneity by single-cell genome and transcriptome analysis

    • Principal Investigator
      Kato Mamoru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical genome science
    • Research Institution
      National Cancer Center Japan
  •  Elucidation of molecular mechanisms underlying colon carcinogenesis and discovery of therapeutic targets by using a novel in vitro modelPrincipal Investigator

    • Principal Investigator
      Hippo Yoshitaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Lung carcinogenesis by genetic reconstitution using organoids derived from normal lung in mice

    • Principal Investigator
      Ochiai Masako
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      National Cancer Center Japan
  •  Genetic reconstitution of pancreatic ductal carcinogenesis with murine primary cellsPrincipal Investigator

    • Principal Investigator
      Hippo Yoshitaka
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  SNPアレイを用いたスキルス胃癌細胞株のゲノムコピー数解析Principal Investigator

    • Principal Investigator
      筆宝 義隆
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Systemic Analysis of transcriptional network in cancer

    • Principal Investigator
      ABURATANI Hiroyuki
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Applied genomics
    • Research Institution
      The University of Tokyo
  •  胃癌の分子標的に対する系統的モノクローナル抗体作成とその診断・治療への応用Principal Investigator

    • Principal Investigator
      筆宝 義隆
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 進化するがん創薬2019

    • Author(s)
      清宮 啓之編(筆宝義隆 分担執筆)
    • Total Pages
      344
    • Publisher
      化学同人
    • ISBN
      9784759817331
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Book] 患者由来がんモデルを用いたがん研究実践ガイド2019

    • Author(s)
      佐々木 博己編(筆宝義隆 分担執筆)
    • Total Pages
      294
    • Publisher
      羊土社
    • ISBN
      9784758122429
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Book] 患者由来がんモデルを用いたがん研究実践ガイド2019

    • Author(s)
      佐々木 博己編(筆宝義隆 分担執筆)
    • Total Pages
      294
    • Publisher
      羊土社
    • ISBN
      9784758122429
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Book] 患者由来がんモデルを用いたがん研究実践ガイド2019

    • Author(s)
      佐々木博己編集(丸喜明、筆宝義隆分担執筆)
    • Total Pages
      294
    • Publisher
      羊土社
    • ISBN
      9784758122429
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Book] 進化するがん創薬2019

    • Author(s)
      清宮 啓之編(筆宝義隆 分担執筆)
    • Total Pages
      344
    • Publisher
      化学同人
    • ISBN
      9784759817331
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Journal Article] Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives2021

    • Author(s)
      Maru Yoshiaki、Hippo Yoshitaka
    • Journal Title

      Frontiers in Genetics

      Volume: 12 Pages: 798628-798628

    • DOI

      10.3389/fgene.2021.798628

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-21K08019, KAKENHI-PROJECT-21K09483, KAKENHI-PROJECT-21K09506
  • [Journal Article] Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model2021

    • Author(s)
      Ono H, Arai Y, Furukawa E, Narushima D, Matsuura T, Nakamura H, Shiokawa D, Nagai M, Imai T, Mimori K, Okamoto K, Hippo Y, Shibata T, Kato M.
    • Journal Title

      BMC Biology

      Volume: 19(1) Pages: 207-207

    • DOI

      10.1186/s12915-021-01147-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H05039, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-21K08019
  • [Journal Article] Probing the tumorigenic potential of genetic interactions reconstituted in murine fallopian tube organoids2021

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Tatsumi Yasutoshi、Nakamura Yuki、Yao Ryoji、Noda Tetsuo、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      The Journal of Pathology

      Volume: 255 Pages: 177-189

    • DOI

      10.1002/path.5752

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-21H02770, KAKENHI-PROJECT-20K08199, KAKENHI-PROJECT-21K08019, KAKENHI-PROJECT-21K09483, KAKENHI-PROJECT-21K09506
  • [Journal Article] Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition2021

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Tatsumi Yasutoshi、Nakamura Yuki、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      Oncogenesis

      Volume: 10 Pages: 46-46

    • DOI

      10.1038/s41389-021-00337-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-20K08199, KAKENHI-PROJECT-21K08019, KAKENHI-PROJECT-21K09483, KAKENHI-PROJECT-21K09506
  • [Journal Article] Precision modeling of gall bladder cancer patients in mice based on orthotopic implantation of organoid-derived tumor buds.2021

    • Author(s)
      Kato Shingo、Fushimi Kentaro、Yabuki Yuichiro、Maru Yoshiaki、Hasegawa Sho、Matsuura Tetsuya、Kurotaki Daisuke、Suzuki Akihiro、Kobayashi Noritoshi、Yoneda Masato、Higurashi Takuma、Enaka Makiko、Tamura Tomohiko、Hippo Yoshitaka、Nakajima Atsushi
    • Journal Title

      Oncogenesis

      Volume: 10 Pages: 1-13

    • DOI

      10.1038/s41389-021-00322-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0412, KAKENHI-PROJECT-18K07950, KAKENHI-PROJECT-19K16840, KAKENHI-PROJECT-19K07518, KAKENHI-PROJECT-21K08019
  • [Journal Article] Recent Advances in Implantation-Based Genetic Modeling of Biliary Carcinogenesis in Mice2021

    • Author(s)
      Izumiya Masashi、Kato Shingo、Hippo Yoshitaka
    • Journal Title

      Cancers

      Volume: 13 Pages: 2292-2292

    • DOI

      10.3390/cancers13102292

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16840, KAKENHI-PROJECT-19K07518, KAKENHI-PROJECT-21K08019
  • [Journal Article] Twists and turns in Kras-driven tumor initiation2021

    • Author(s)
      Maru Yoshiaki、Hippo Yoshitaka
    • Journal Title

      Aging

      Volume: 13 Pages: 24477-24479

    • DOI

      10.18632/aging.203726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-21K08019, KAKENHI-PROJECT-21K09483, KAKENHI-PROJECT-21K09506
  • [Journal Article] Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix.2020

    • Author(s)
      Maru Y, Kawata A, Taguchi A, Ishii Y, Baba S, Mori M, Nagamatsu T, Oda K, Kukimoto I, Osuga Y, Fujii T, Hippo Y.
    • Journal Title

      Cancers

      Volume: 12 Pages: 1-15

    • DOI

      10.3390/cancers12030694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-18K09249, KAKENHI-PROJECT-19K07636, KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] Organoid-based Ex Vivo Reconstitution of Kras-driven Pancreatic Ductal Carcinogenesis2020

    • Author(s)
      Matsuura Tetsuya、Maru Yoshiaki、Izumiya Masashi、Hoshi Daisuke、Kato Shingo、Ochiai Masako、Hori Mika、Yamamoto Shogo、Tatsuno Kenji、Imai Toshio、Aburatani Hiroyuki、Nakajima Atsushi、Hippo Yoshitaka
    • Journal Title

      Carcinogenesis

      Volume: - Pages: 1-12

    • DOI

      10.1093/carcin/bgz122

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07195, KAKENHI-PROJECT-18K07932, KAKENHI-PROJECT-19K16840, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-17K08755, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823, KAKENHI-ORGANIZER-19H05739
  • [Journal Article] An organoid-based carcinogenesis model induced by in vitro chemical treatment2020

    • Author(s)
      Naruse Mie、Masui Ryoichi、Ochiai Masako、Maru Yoshiaki、Hippo Yoshitaka、Imai Toshio
    • Journal Title

      Carcinogenesis

      Volume: -

    • DOI

      10.1093/carcin/bgaa011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08755, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] Kras-driven heterotopic tumor development from hepatobiliary organoids2019

    • Author(s)
      Masako Ochiai, Yasunori Yoshihara, Yoshiaki Maru, Tetsuya Matsuura, et al.
    • Journal Title

      Carcinogenesis

      Volume: 印刷中 Pages: 1142-1152

    • DOI

      10.1093/carcin/bgz024

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08755, KAKENHI-PROJECT-18K07932, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823, KAKENHI-PROJECT-26430134
  • [Journal Article] Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors2019

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      Gynecologic Oncology

      Volume: 154 Pages: 189-198

    • DOI

      10.1016/j.ygyno.2019.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] Current Status of Patient-Derived Ovarian Cancer Models2019

    • Author(s)
      Maru Yoshiaki、Hippo Yoshitaka
    • Journal Title

      Cells

      Volume: 8 Pages: 505-505

    • DOI

      10.3390/cells8050505

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells2019

    • Author(s)
      Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo MM, Waku T, Kobayashi A.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Pages: 3344-3344

    • DOI

      10.3390/ijms20133344

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PROJECT-17K19624
  • [Journal Article] Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinoma2019

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Ebisawa Keiko、Odaka Akiko、Sugiyama Takahiro、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 2992-3005

    • DOI

      10.1111/cas.14119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-18K16823
  • [Journal Article] Shortcuts to intestinal carcinogenesis by genetic engineering in organoids2019

    • Author(s)
      Maru Yoshiaki、Onuma Kunishige、Ochiai Masako、Imai Toshio、Hippo Yoshitaka
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 858-866

    • DOI

      10.1111/cas.13938

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08755, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] SET/PP2A/E2F1 Axis Enhances Gastric Cancer Cell Stemness2018

    • Author(s)
      Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek M, Matsuura T, Hippo Y, Usui T, Ohama T, and Sato K.
    • Journal Title

      Mol. Cancer. Res

      Volume: 16 Pages: 554-563

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Journal Article] Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis.2018

    • Author(s)
      Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T*, Sato K
    • Journal Title

      Mol Cancer Res

      Volume: 16 Issue: 3 Pages: 554-563

    • DOI

      10.1158/1541-7786.mcr-17-0393

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-17H03915, KAKENHI-PROJECT-15J07273, KAKENHI-PROJECT-16J01893, KAKENHI-PROJECT-16H06276
  • [Journal Article] Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.2017

    • Author(s)
      Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y, Nagase H. Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.
    • Journal Title

      Gynecol Oncol.

      Volume: 144(2) Pages: 377-383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Journal Article] Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells2017

    • Author(s)
      Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y, Tanuma N
    • Journal Title

      Oncol Lett

      Volume: 14(6) Pages: 6863-6868

    • DOI

      10.3892/ol.2017.7098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-17K10796, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-16K19745
  • [Journal Article] Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.2017

    • Author(s)
      Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y and Nagase H.
    • Journal Title

      Gynecologic Oncology

      Volume: - Issue: 2 Pages: 377-383

    • DOI

      10.1016/j.ygyno.2016.11.045

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-16H06277
  • [Journal Article] Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation2017

    • Author(s)
      Kangawa Yumi、Yoshida Toshinori、Maruyama Kiyoshi、Okamoto Minako、Kihara Tohru、Nakamura Michi、Ochiai Masako、Hippo Yoshitaka、Hayashi Shim-mo、Shibutani Makoto
    • Journal Title

      Food and Chemical Toxicology

      Volume: 100 Pages: 103-114

    • DOI

      10.1016/j.fct.2016.12.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Journal Article] Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis2017

    • Author(s)
      Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y, Nagase H
    • Journal Title

      Gynecol Oncol

      Volume: 144 Pages: 377-383

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Journal Article] Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells.2017

    • Author(s)
      Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y and Tanuma N.
    • Journal Title

      Oncology Lett.

      Volume: 14 Pages: 6863-6868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Journal Article] Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation.2017

    • Author(s)
      Kangawa Y, Yoshida T, Maruyama K, Okamoto M, Kihara T, Nakamura M, Ochiai M, Hippo Y, Hayashi SM, Shibutani M.
    • Journal Title

      Food Chem Toxicol

      Volume: 100 Pages: 103-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Journal Article] Lentivirus-based stable gene delivery into intestinal organoids2016

    • Author(s)
      Maru Y, Orihashi K, Hippo Y
    • Journal Title

      Methods Mol Biol

      Volume: 1422 Pages: 13-21

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Journal Article] Lentivirus-based stable gene delivery into intestinal organoids.2016

    • Author(s)
      Maru Y, Orihashi K, Hippo Y. Lentivirus-based stable gene delivery into intestinal organoids.
    • Journal Title

      Methods Mol Biol,

      Volume: 1422 Pages: 13-21

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Journal Article] Overexpression of MUC13 is associated with intestinal type gastric cancer2005

    • Author(s)
      Shimamura T, Hippo Y et al.
    • Journal Title

      Cancer Science 5(In press)

    • Data Source
      KAKENHI-PROJECT-15790339
  • [Journal Article] Identification of Soluble Amino Terminal Fragment of Glypican-3 as a Serological Marker for Early Stage Hepatocellular Carcinoma.2004

    • Author(s)
      Hippo Y, Midorikawa Y, Aburatani H
    • Journal Title

      Cancer Research 64

      Pages: 2418-2423

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16101006
  • [Journal Article] Identification of Soluble Amino Terminal Fragment of Glypican-3 as a Serological Marker for Early Stage Hepatocellular Carcinoma2004

    • Author(s)
      Hippo Y, et al.
    • Journal Title

      Cancer Research 64(7)

      Pages: 2418-2423

    • Data Source
      KAKENHI-PROJECT-16101006
  • [Presentation] ヒト膵液由来オルガノイドを用いたIPMN モデルの構築と分化に関する検討2022

    • Author(s)
      喜多絵美里,筆宝義隆
    • Organizer
      第108回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-19K07518
  • [Presentation] Banking of patient-derived gynecologic cancer organoids toward implementation of precision medicine.2021

    • Author(s)
      Yoshiaki Maru, Yoshitaka Hippo
    • Organizer
      1ST JCA-AACR PRECISION CANCER MEDICINE INTERNATIONAL CONFERENCE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08019
  • [Presentation] Banking of patient-derived gynecologic cancer organoids toward implementation of precision medicine2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      1ST JCA-AACR PRECISION CANCER MEDICINE INTERNATIONAL CONFERENCE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] がん特異的遺伝子異常を再構成したマウスオルガノイドによる発がん協調作用の検出2021

    • Author(s)
      筆宝義隆
    • Organizer
      第39回ヒト細胞学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08019
  • [Presentation] CRISPR-dCas9-based transcription factor blockage at the MYCN locus induces caspase 2-mediated neuroblastoma cell death2021

    • Author(s)
      K. Nakatani, T. Sakuma, T. Yamamoto, Y. Hippo, Y. Suenaga
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08610
  • [Presentation] Banking of patient-derived gynecologic cancer organoids toward implementation of precision medicine2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      1ST JCA-AACR PRECISION CANCER MEDICINE INTERNATIONAL CONFERENCE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09506
  • [Presentation] 進行胆膵癌における胆汁検体由来オルガノイドの有用性に関する検討2021

    • Author(s)
      喜多絵美里、筆宝義隆
    • Organizer
      第101回日本消化器内視鏡学会総会
    • Data Source
      KAKENHI-PROJECT-19K07518
  • [Presentation] Probing pro-tumorigenic genetic interactions using murine fallopian tube organoids2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K09506
  • [Presentation] 子宮癌肉腫の発症機構解明と治療戦略構築に向けたマウスおよび患者由来オルガノイドの活用2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第17回日本病理学会カンファレンス
    • Data Source
      KAKENHI-PROJECT-21K09483
  • [Presentation] Proof of concept for therapeutic targeting of the MYCN/NCYM positive feedback regulation in the neuroblastoma2021

    • Author(s)
      K. Nakatani, T. Matsuo, K. Matsuo, T. Tamada, T. Sakuma, T. Yamamoto, Y. Hippo, Y. Suenaga
    • Organizer
      先端モデル動物支援プラットフォーム(AdAMS)、2021年度若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-21K08610
  • [Presentation] Banking of patient-derived gynecologic cancer organoids toward implementation of precision medicine2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      1ST JCA-AACR PRECISION CANCER MEDICINE INTERNATIONAL CONFERENCE
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09483
  • [Presentation] Probing pro-tumorigenic genetic interactions using murine fallopian tube organoids2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 子宮癌肉腫の発症機構解明と治療戦略構築に向けたマウスおよび患者由来オルガノイドの活用2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第17回日本病理学会カンファレンス
    • Data Source
      KAKENHI-PROJECT-21K09506
  • [Presentation] 子宮癌肉腫の発症機構解明と治療戦略構築に向けたマウスおよび患者由来オルガノイドの活用2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第17回日本病理学会カンファレンス
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] Probing pro-tumorigenic genetic interactions using murine fallopian tube organoids2021

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K09483
  • [Presentation] オルガノイド培養技術の婦人科がん領域への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      第21回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] マウスおよび患者由来のがんオルガノイドモデル確立と創薬への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      日本学術会議シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07518
  • [Presentation] 3次元オルガノイド培養を用いたがんの本態解明と個別化医療・創薬への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      (株)情報機構 細胞培養セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 婦人科領域における患者由来オルガノイド研究の新展開2020

    • Author(s)
      筆宝義隆
    • Organizer
      第4回患者由来がんモデル講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイドを用いたex vivo発がんモデルの確立とがん予防への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      第27回日本がん予防学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] マウスおよび患者由来のがんオルガノイドモデル確立と創薬への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      日本学術会議シンポジウム「創薬を加速させる革新的な細胞・臓器・個体モデル」
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 患者由来オルガノイドの婦人科正常組織および腫瘍性病変の研究への利用2020

    • Author(s)
      筆宝義隆、丸喜明、田中尚武
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイド発がんモデルが明らかにする子宮内膜の発がんおよび転移促進的な遺伝学的相互作用2020

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイドを用いたex vivo発がんモデルの確立とがん予防への応用2020

    • Author(s)
      筆宝義隆
    • Organizer
      第27回日本がん予防学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07518
  • [Presentation] 婦人科がん研究における患者由来オルガノイドの活用2020

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第24回日本がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイド培養を用いた婦人科腫瘍の統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイド培養を用いた婦人科腫瘍の統合的研究2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 患者由来卵巣がんからのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第61回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 細胞診検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、小高亜紀子、伊丹真紀子、筆宝義隆
    • Organizer
      第60回日本臨床細胞学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 膵腺房細胞癌のオルガノイド培養2019

    • Author(s)
      星大輔、喜多絵美里、丸喜明、筆宝義隆
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] オルガノイドを用いた婦人科がんの統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイドを用いた婦人科がんの統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第1回日本癌学会若手の会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] マウスオルガノイドを用いた臓器横断的ex vivo発がんモデルの確立2019

    • Author(s)
      筆宝義隆
    • Organizer
      第32回モロシヌス研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 3次元オルガノイド培養法を用いた膵液検体由来IPMNモデルの樹立2019

    • Author(s)
      喜多絵美里、筆宝義隆、辻本彰子、須藤研太郎、中村和貴、石井浩、山口武人、高山亘
    • Organizer
      第50回日本膵臓学会大会
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] オルガノイドを用いた婦人科がんの統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 患者由来婦人科がん検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第37回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 細胞診検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、小高亜紀子、伊丹真紀子、筆宝義隆
    • Organizer
      第60回日本臨床細胞学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイドを用いた婦人科がんの統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第1回日本癌学会若手の会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 膵・胆道癌における胆汁検体を用いたオルガノイド培養法の樹立2019

    • Author(s)
      喜多絵美里、筆宝義隆、山口武人
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] Development of new organoid model in patients with advanced biliary cancer2019

    • Author(s)
      Emiri Kita, Yoshitaka Hippo, Taketo Yamaguchi
    • Organizer
      第27回日本消化器関連学会週間
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] 正常子宮内膜オルガノイドへの遺伝子導入による高転移性がん細胞の直接誘導2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第28回日本がん転移学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 患者由来婦人科がん検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第37回日本ヒト細胞学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] マウスおよび患者由来オルガノイドを用いた婦人科がんの統合的研究2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第7回細胞凝集研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 患者由来卵巣がんからのオルガノイド培養2019

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第61回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 子宮内膜オルガノイドへのin vitro遺伝子導入による癌肉腫の誘導2018

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] Development of three dimensional culture method for ovarian cancer toward clinical application2018

    • Author(s)
      Naotake Tanaka, Yoshiaki Maru,Kiyomi Suzuka, Makiko Itami, Yoshitaka Hippo
    • Organizer
      International Gynecologic Cancer Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立とその臨床応用へ向けた検討2018

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第36回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] マウス卵管由来オルガノイドを用いた高異型度漿液性卵巣癌に対する包括的な疾患モデル作製2018

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍に対する3次元培養法の最適化2018

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] Per-oral pancreatoscopy provides novel technology -New methods for 3D culture of human-derived IPMN cells-2018

    • Author(s)
      Emiri Kita, Kentaro Sudo, Taro Hara, Yoshiaki Maru, Taketo Yamaguchi, Yoshitaka Hippo
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立とその臨床応用の検討2018

    • Author(s)
      丸喜明、田中尚武、鈴鹿清美、伊丹真紀子, 筆宝義隆
    • Organizer
      第56回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 変異遺伝子のin vitro再構成による胆管細胞発がんの誘導2018

    • Author(s)
      泉谷昌志,吉原靖典,丸喜明,落合雅子,松浦哲也,今井俊夫,筆宝義隆
    • Organizer
      第77回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07932
  • [Presentation] New approach for organoid culture in patients with advanced biliary tumor2018

    • Author(s)
      Emiri Kita、Yoshitaka Hippo、 Yoshiaki Maru、Taketo Yamaguchi、 Kazuyoshi Nakamura
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08755
  • [Presentation] オルガノイドへの遺伝子導入による子宮内膜発がん2017

    • Author(s)
      丸 喜明、筆宝 義隆
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] マウスオルガノイドを用いた子宮内膜発がん過程の再現2017

    • Author(s)
      丸喜明、筆宝義隆
    • Organizer
      第32回発癌病理研究会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイド培養を用いた卵巣がん発がんモデルの開発2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立に向けた組み2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第35回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 3次元オルガノイド培養のがん研究への応用2017

    • Author(s)
      筆宝 義隆
    • Organizer
      第26回日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] オルガノイド培養を用いた細胞レベルの子宮体がん発がんモデルの開発2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第58回日本臨床細胞学会総会春季大会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 3次元オルガノイド培養のがん研究への応用2017

    • Author(s)
      筆宝義隆
    • Organizer
      第26回日本癌病態治療研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイドを用いた発がん過程のin vitro再構成2017

    • Author(s)
      筆宝義隆
    • Organizer
      第58回日本臨床細胞学会総会春季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイド移植モデルおよびPDXによる胆道・膵管発がん再構成2017

    • Author(s)
      筆宝 義隆
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] オルガノイド移植モデルおよびPDXによる胆道・膵管発がん再構成2017

    • Author(s)
      筆宝義隆
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイドを用いた発がん過程のin vitro再構成2017

    • Author(s)
      筆宝 義隆
    • Organizer
      第58回日本臨床細胞学会総会春季大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] in vitroモデルが明らかにするマウス膵管発がんにおけるKras遺伝子材の重要性2016

    • Author(s)
      松浦哲也、落合雅子、中島淳、今井俊夫、筆宝義隆
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] レンチウイルスを用いたマウス胃細胞からの発がん誘導2016

    • Author(s)
      丸 喜明、松浦 哲也、落合 雅子、筆宝 義隆
    • Organizer
      第20回日本がん分子標的治療学会学術集会
    • Place of Presentation
      別府国際コンベンションセンター(大分県・別府市)
    • Year and Date
      2016-05-30
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] オルガノイドを用いた胆嚢発がんモデルの確立2016

    • Author(s)
      筆宝義隆、丸喜明、落合雅子、松浦哲也、今井俊夫
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発―化学発がん・予防研究への応用に向けて2016

    • Author(s)
      落合雅子、松浦哲也、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2016
    • Place of Presentation
      名古屋
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] Induction of Pancreatic Ductal Adenocarcinoma from Primary Murine Pancreatic Cells2016

    • Author(s)
      Tetsuya Matsuura, Masako Ochiai, Toshio Imai, Yoshitaka Hippo
    • Organizer
      「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      大津
    • Year and Date
      2016-02-03
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発2016

    • Author(s)
      落合雅子、松浦哲也、中釜斉、筆宝義隆、今井俊夫.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] オルガノイドを用いた卵巣がんモデルの開発2016

    • Author(s)
      丸喜明、落合雅子、今井俊夫、筆宝義隆
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] オルガノイドを用いた胆嚢発がんモデルの確立2016

    • Author(s)
      筆宝義隆、丸喜明、落合雅子、松浦哲也、今井俊夫
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] in vitroモデルが明らかにするマウス膵管発がんにおけるKras遺伝子材の重要性2016

    • Author(s)
      松浦哲也、落合雅子、中島淳、今井俊夫、筆宝義隆
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K06916
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発―化学発がん・予防研究への応用に向けて2016

    • Author(s)
      落合雅子、松浦哲也、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2016名古屋
    • Place of Presentation
      愛知県・名古屋市
    • Year and Date
      2016-07-01
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] マウス正常大腸上皮細胞の3次元培養によるin vitro発がんモデルの開発2016

    • Author(s)
      落合雅子、松浦哲也、中釜斉、筆宝義隆、今井俊夫
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      神奈川県・横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] マウス正常腸管上皮の3次元培養法を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第30回発癌病理研究会
    • Place of Presentation
      香川県小豆郡土庄町
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] ウス正常腸管上皮の3次元培養法を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第30回発がん病理研究会
    • Place of Presentation
      小豆島
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス正常腸管上皮細胞の3次元培養系を用いる発がん再構成系に対するPhIPの修飾作用2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、今井俊夫、筆宝義隆
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] 正常上皮細胞の3次元培養によるin vitro発がんモデルの開発 -化学発がん・予防研究への応用に向けて2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      がん予防学術大会2015さいたま
    • Place of Presentation
      埼玉県さいたま市
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] 正常上皮細胞の3次元培養によるin vitro発がんモデルの開発-化学発がん・予防研究への応用に向けて2015

    • Author(s)
      落合雅子、松浦哲也、中釜 斉、筆宝義隆、今井俊夫
    • Organizer
      第22回日本がん予防学会
    • Place of Presentation
      さいたま
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス初代培養細胞による膵管がん発がん過程の再現2015

    • Author(s)
      松浦哲也、筆宝義隆
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] Induction of Pancreatic Ductal Adenocarcinoma from Primary Murine Pancreatic Cells2015

    • Author(s)
      Tetsuya Matsuura, Kaoru Orihashi, Masako Ochiai, Hitoshi Nakagama, Toshio Imai, Yoshitaka Hippo
    • Organizer
      第74回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] 3次元初代培養を用いた膵管・胆道発がんモデルの確立2015

    • Author(s)
      筆宝義隆、松浦哲也、落合雅子、今井俊夫、折橋郁、丸喜明
    • Organizer
      第30回発がん病理研究会
    • Place of Presentation
      小豆島
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] マウス初代培養細胞を用いた発がんのin vitro再構成2014

    • Author(s)
      筆宝義隆
    • Organizer
      第2回細胞凝集研究会
    • Place of Presentation
      福岡
    • Year and Date
      2014-12-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス初代培養細胞による膵管がん発がん過程の再現

    • Author(s)
      松浦哲也、筆宝義隆
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] Three-dimensional Cell Culture for Cancer Research

    • Author(s)
      Yoshitaka Hippo
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] Induction of Pancreatic Ductal Adenocarcinoma from Primary Murine Pancreatic Cells

    • Author(s)
      Tetsuya Matsuura, Kaoru Orihashi, Masako Ochiai, Toshio Imai, Hitoshi Nakagama and Yoshitaka Hippo
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26670391
  • [Presentation] マウス肝臓初代培養細胞を用いた新規肝内胆管がんモデルの確立

    • Author(s)
      落合雅子,折橋 郁,松浦哲也,今井俊夫,中釜 斉,筆宝義隆
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430134
  • [Presentation] In vitro reconstitution of Kras-dependent tumorigenesis in the intestine and the stomach

    • Author(s)
      Kaoru Orihashi, Tetsuya Matsuura, Masako Ochiai, Toshio Imai, Hitoshi Nakagama, Yoshitaka Hippo
    • Organizer
      第73回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス初代培養細胞での遺伝子異常再構成による多段階発がん過程の再現

    • Author(s)
      筆宝義隆
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-26290044
  • [Presentation] マウス肝臓初代培養細胞を用いた新規肝内胆管がんモデルの確立

    • Author(s)
      落合雅子,折橋 郁,松浦哲也,今井俊夫,中釜 斉,筆宝義隆
    • Organizer
      第29回発癌病理研究会
    • Place of Presentation
      福島県いわき市
    • Year and Date
      2014-09-01 – 2014-09-03
    • Data Source
      KAKENHI-PROJECT-26430134
  • 1.  丸 喜明 (30742754)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 57 results
  • 2.  Tanaka Naotake (80236611)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 3.  Kita Emiri (20773980)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 4.  泉谷 昌志 (90532739)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 5.  Ochiai Masako (90150200)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 6.  末永 雄介 (80581793)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  ABURATANI Hiroyuki (10202657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  TSUTSUMI Shuichi (30345152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ISHIKAWA Shumpei (50418638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MLDORIKAWA Yutaka (10292905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  Kato Mamoru (40391916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SHIBATA Tatsuhiro (90311414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Taketo Yamaguchi (00241969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 14.  金城 聖文 (50401302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  砂河 孝行 (40418637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  新井 康仁 (80222727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  落合 頼業 (90816026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  井下 尚子 (20300741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  瀬戸口 大毅 (90869926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  井内 俊彦 (80370881)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  海老沢 桂子 (10933210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  安藤 清宏 (10455389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  堀 美香 (60598043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  鈴鹿 清美 (30334189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  ODA Katsutoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  MORI Mayuyo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  TATSUMI Yasutoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  KAWAI Masaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  TANAKA Yukichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  TANAKA Hideo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  OHAMA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  OSHIMA Masanobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  ABE Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  柊元 巌
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  田口 歩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  三森 功士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  八尾 良司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  日暮 琢磨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  加藤 真吾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 40.  島 礼
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  佐藤 郁郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  三浦 康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  佐藤 雅美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  田沼 延公
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  野村 美有樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  井上 維
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  辰野 健二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  小林 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  和久 剛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  田中 恵太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  松浦 正明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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