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TANAKA NAOTAKE  田中 尚武

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田中 尚武  タナカ ナオタケ

TANAKA Naotake  田中 尚武

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Researcher Number 80236611
Affiliation (Current) 2022: 千葉県がんセンター(研究所), 婦人科, 診療部長
Affiliation (based on the past Project Information) *help 2022: 千葉県がんセンター(研究所), その他部局等, その他
2017 – 2021: 千葉県がんセンター(研究所), 婦人科, 部長
2001: CHIBA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, Research Assistant, 大学院・医学研究院, 助手
2000: 千葉大学, 医学部, 助手
1994: Chiba Univ.Sch.Med.Assistant, 医学部・付属病院, 助手 … More
1994: 千葉大学, 医学部附属病院, 助手
1993: 千葉大学, 医学部・附属病院, 助手
1991: 千葉大学, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Except Principal Investigator
Obstetrics and gynecology / Tumor biology and related fields / Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
卵巣癌 / 培養細胞 / 転移 / 無血清培地 / ウロキナーゼ / プロテアーゼインヒビター / 第三染色体 / 遺伝子増幅 / 遺伝子発現 / β-catenin … More / γ-catenin / OVARIAN CANCER / CHROMOSOME 3 / GENE AMPLIFICATION / CULTURED CELL / GRNE EXPRESSION / BETA-CATENIN / GAMMA-CATENIN / 卵巣がん / オルガノイド / 患者由来がんモデル / 薬剤感受性 / 3次元培養 … More
Except Principal Investigator
卵巣癌 / 無血清培養 / Ovarian cancer / オルガノイド / 癌肉腫 / 子宮体がん / 癌 / 培養細胞株 / 無血清培地 / 増殖因子 / 蚕白分解酵素 / 浸潤・転移 / 蛋白分解酵素 / ヒト卵巣癌培養細胞株 / 生理活性物質 / ヒト子宮内膜癌 / Cell lines / Serum-free medium / Growth factors / Cytokines / Proteases / Invasion-metastasis / モノクローナル抗体 / 免疫複合体 / 腹水 / 抗原抗体複合物 / Monoclonal antibody / Immune complex / serum-free culture / Ascites / 子宮がん / 転移 / Kras / Pten / マウス / 子宮内膜がん / 発がん / モデル / がん肉腫 / 子宮 / 遺伝子 / 三次元培養 Less
  • Research Projects

    (8 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (22 People)
  •  卵巣がんオルガノイドを活用した治療抵抗性機構解明と治療効果予測マーカー開発Principal Investigator

    • Principal Investigator
      田中 尚武
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Elucidation of the mechanism underlying tumorigenesis and development of therapeutic strategy for uterine carcinosarcoma using murine and patient-derived organoids

    • Principal Investigator
      鈴鹿 清美
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  卵巣がんの本態解明および治療戦略構築のためのオルガノイド培養を用いた統合的研究Principal Investigator

    • Principal Investigator
      田中 尚武
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  Organoid-based Modeling of Endometrial Carcinogenesis

    • Principal Investigator
      Hippo Yoshitaka
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Chiba Cancer Center (Research Institute)
  •  MOLECULAR MECHANISM INVOLVED IN ONCOGENESIS AND PROGRESSION OF OVARIAN CANCERPrincipal Investigator

    • Principal Investigator
      TANAKA Naotake
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      CHIBA UNIVERSITY
  •  種々の細胞外基質分解抑制酵素による卵巣癌の浸潤・転移抑制作用とその臨床応用Principal Investigator

    • Principal Investigator
      田中 尚武
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba University
  •  Development of an early detection method and specific immunotherapy of ovarian cancers

    • Principal Investigator
      SEKIYA Souei
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba Univ.
  •  Growth regulatory factors of ovarian cancer

    • Principal Investigator
      TAKAMIZAWA Hiroyoshi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Chiba Univ

All 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors2019

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      Gynecologic Oncology

      Volume: 154 Pages: 189-198

    • DOI

      10.1016/j.ygyno.2019.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-18K16823
  • [Journal Article] β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells2019

    • Author(s)
      Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo MM, Waku T, Kobayashi A.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Pages: 3344-3344

    • DOI

      10.3390/ijms20133344

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PROJECT-17K19624
  • [Journal Article] Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinoma2019

    • Author(s)
      Maru Yoshiaki、Tanaka Naotake、Ebisawa Keiko、Odaka Akiko、Sugiyama Takahiro、Itami Makiko、Hippo Yoshitaka
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 2992-3005

    • DOI

      10.1111/cas.14119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09816, KAKENHI-PROJECT-18K16823
  • [Journal Article] Identification of novel mutations in Japanese ovarian clear cell carcinoma patients using optimized targeted NGS for clinical diagnosis.2017

    • Author(s)
      Maru Y, Tanaka N, Ohira M, Itami M, Hippo Y and Nagase H.
    • Journal Title

      Gynecologic Oncology

      Volume: - Issue: 2 Pages: 377-383

    • DOI

      10.1016/j.ygyno.2016.11.045

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-16H06277
  • [Journal Article] Ex vivo model of non-small cell lung cancer using mouse lung epithelial cells2017

    • Author(s)
      Sato T, Morita M, Tanaka R, Inoue Y, Nomura M, Sakamoto Y, Miura K, Ito S, Sato I, Tanaka N, Abe J, Takahashi S, Kawai M, Sato M, Hippo Y, Shima H, Okada Y, Tanuma N
    • Journal Title

      Oncol Lett

      Volume: 14(6) Pages: 6863-6868

    • DOI

      10.3892/ol.2017.7098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-17K10796, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K19624, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-16K19745
  • [Presentation] 患者由来オルガノイドの婦人科正常組織および腫瘍性病変の研究への利用2020

    • Author(s)
      筆宝義隆、丸喜明、田中尚武
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] オルガノイド培養を用いた婦人科腫瘍の統合的研究2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 患者由来卵巣がんからのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第61回日本婦人科腫瘍学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 細胞診検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、小高亜紀子、伊丹真紀子、筆宝義隆
    • Organizer
      第60回日本臨床細胞学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 患者由来婦人科がん検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第37回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] 細胞診検体からのオルガノイド培養2019

    • Author(s)
      丸喜明、田中尚武、小高亜紀子、伊丹真紀子、筆宝義隆
    • Organizer
      第60回日本臨床細胞学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09816
  • [Presentation] Development of three dimensional culture method for ovarian cancer toward clinical application2018

    • Author(s)
      Naotake Tanaka, Yoshiaki Maru,Kiyomi Suzuka, Makiko Itami, Yoshitaka Hippo
    • Organizer
      International Gynecologic Cancer Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍に対する3次元培養法の最適化2018

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立とその臨床応用の検討2018

    • Author(s)
      丸喜明、田中尚武、鈴鹿清美、伊丹真紀子, 筆宝義隆
    • Organizer
      第56回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立とその臨床応用へ向けた検討2018

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子、筆宝義隆
    • Organizer
      第36回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 患者由来卵巣腫瘍からの3次元初代培養とその臨床応用へ向けた検討2018

    • Author(s)
      丸喜明、田中尚武、伊丹真紀子
    • Organizer
      第57回日本臨床細胞学会秋期大会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイド培養を用いた卵巣がん発がんモデルの開発2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第106回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] 卵巣腫瘍からの3次元培養法の確立に向けた組み2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第35回日本ヒト細胞学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • [Presentation] オルガノイド培養を用いた細胞レベルの子宮体がん発がんモデルの開発2017

    • Author(s)
      丸 喜明、田中尚武、筆宝義隆
    • Organizer
      第58回日本臨床細胞学会総会春季大会
    • Data Source
      KAKENHI-PROJECT-17K19624
  • 1.  SEKIYA Souei (00092065)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  Hippo Yoshitaka (30359632)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 18 results
  • 3.  丸 喜明 (30742754)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 17 results
  • 4.  TAKAMIZAWA Hiroyoshi (60009107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  FUJIMURA S (80143270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MITSUHASHI Akira (40302541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  布山 隆史 (90228271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  鈴鹿 清美 (30334189)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  河田 誠
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SEKIYA S
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TANAKA Hideo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  KAWAI Masaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  田中 恵太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  島 礼
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  佐藤 郁郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  三浦 康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  佐藤 雅美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  田沼 延公
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  野村 美有樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  井上 維
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  小林 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  和久 剛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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