• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Chuma Makoto  中馬 誠

ORCIDConnect your ORCID iD *help
… Alternative Names

Makoto Chuma  中馬 誠

CHUMA Makoto  中馬 誠

Less
Researcher Number 30360910
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2022 – 2023: 横浜市立大学, 附属市民総合医療センター, 准教授
2021: 横浜市立大学, 附属市民総合医療センター, 診療教授
2016: 横浜市立大学, 附属市民総合医療センター, 准教授
2015: 横浜市立大学, 付属市民総合医療センター, 准教授
2014: 横浜市立大学, 附属市民総合医療センター, 准教授 … More
2010: 北海道大学, 北海道大学病院, 助教
2010: Hokkaido University, 病院, 助教
2009: Hokkaido University, 大学病院, 助教
2008: Hokkaido University, 病院, 助教 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology
Keywords
Principal Investigator
分子標的治療 / 肝癌 / CD8陽性T細胞 / 免疫 / IKK / β-catenin / CD8+T細胞 / 抗 PD-L1抗体治療 / バイオマーカー / 免疫チェックポイント阻害剤 … More / 肝細胞癌 / 脂肪性肝炎 / 酸化ストレス / ストレス関連遺伝子 / Heat shock factor / HSF1 / 肝癌発生 / 網羅的探索 / マイクロアレイ / RBM5 / RNA結合タンパク / 癌進展 … More
Except Principal Investigator
real-time PCR法 / real-time PCR / ペプチド核酸 / MGBプローブ / 核酸アナログ / 変異株定量 / 変異株 / 薬剤耐性 / 肝炎ウイルス Less
  • Research Projects

    (4 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (12 People)
  •  Examination of immunotherapy improvement through CD8+ T cell induction of refractory hepatocellular carcinoma and, construction of biomarkers.Principal Investigator

    • Principal Investigator
      Chuma Makoto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Yokohama City University
  •  Investigation of the HSF1 signaling pathway as the molecular targeted therapies for hepatocellular carcinoma.Principal Investigator

    • Principal Investigator
      Makoto Chuma
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Yokohama City University
  •  Molecular Screening by Microarray analysis for Hepatocarcinogenesis.Principal Investigator

    • Principal Investigator
      CHUMA Makoto
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Hokkaido University
  •  The development of a quantitative assay of a single-nucleotide mutant of drug-resistant hepatitis virus.

    • Principal Investigator
      HIGE Shuhei
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Hokkaido University

All 2022 2021 2016 2015 2014 2011 2010 2009 2008

All Journal Article Presentation Book

  • [Book] Heat shock factor2015

    • Author(s)
      Chuma M
    • Total Pages
      8
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26460982
  • [Book] HSF supports cancer2015

    • Author(s)
      Chuma M
    • Total Pages
      20
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26460982
  • [Journal Article] Impact of psoas muscle index assessed by a simple measurement method on tolerability and duration of continued treatment with sorafenib in hepatocellular carcinoma patients2022

    • Author(s)
      Ogushi Katsuaki、Chuma Makoto、Numata Kazushi、Nozaki Akito、Moriya Satoshi、Uojima Haruki、Kondo Masaki、Morimoto Manabu、Maeda Shin
    • Journal Title

      European Journal of Gastroenterology & Hepatology

      Volume: Publish Ahead of Print Issue: 7 Pages: 1-1

    • DOI

      10.1097/meg.0000000000002346

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08425, KAKENHI-PROJECT-21K07899
  • [Journal Article] The change rate in serum nitric oxide may affect lenvatinib therapy in hepatocellular carcinoma.2022

    • Author(s)
      Kawamura A, Uojima H, Chuma M, Shao X, Hidaka H, Nakazawa T, Take A, Sakaguchi Y, Numata K, Kako M, Nozaki A, Azuma S, Horio K, Kusano C, Atsuda K
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 912-921

    • DOI

      10.1186/s12885-022-10002-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899, KAKENHI-PROJECT-22K07074
  • [Journal Article] EGFR inhibition reverses resistance to lenvatinib in hepatocellular carcinoma cells2022

    • Author(s)
      He Xiaoping、Hikiba Yohko、Suzuki Yoshimasa、Nakamori Yoshinori、Kanemaru Yushi、Sugimori Makoto、Sato Takeshi、Nozaki Akito、Chuma Makoto、Maeda Shin
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 8007-8007

    • DOI

      10.1038/s41598-022-12076-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08425, KAKENHI-PROJECT-21K07899
  • [Journal Article] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

    • Author(s)
      Makoto Chuma, Hideki Yokoo, Atsushi Hiraoka, Kazuhiko Ueda, et al.
    • Journal Title

      Current Oncology

      Volume: - Issue: 5 Pages: 3259-3271

    • DOI

      10.3390/curroncol29050266

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Journal Article] A prospective observational cohort study of lenvatinib as initial treatment in patients with BCLC-defined stage B hepatocellular carcinoma2022

    • Author(s)
      Kobayashi S, Fukushima T, Ueno M, Moriya S, Chuma M, Numata K, Tsuruya K, Hirose S, Kagawa T, Hattori N, Watanabe T, Matsunaga K, Suzuki M, Uojima H, Hidaka H, Kusano C, Suzuki M, Morimoto M.
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 517-517

    • DOI

      10.1186/s12885-022-09625-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Journal Article] NAFLD exacerbates cholangitis and promotes cholangiocellular carcinoma in mice.2021

    • Author(s)
      Maeda S, Hikiba Y, Fujiwara H, Ikenoue T, Sue S, Sugimori M, Matsubayashi M, Kaneko H, Irie K, Sasaki T, Chuma M
    • Journal Title

      Cancer Sci,

      Volume: 12 Issue: 4 Pages: 1471-1480

    • DOI

      10.1111/cas.14828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07899, KAKENHI-PROJECT-21K07975
  • [Journal Article] Analysis of efficacy of lenvatinib treatment in highly advanced hepatocellular carcinoma with tumor thrombus in the main trunk of the portal vein or tumor with more than 50% liver occupation: A multicenter analysis.2021

    • Author(s)
      1.Chuma M, Uojima H, Hiraoka A, et al.
    • Journal Title

      Hepatology Research

      Volume: 51 Issue: 2 Pages: 201-215

    • DOI

      10.1111/hepr.13592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Journal Article] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis2021

    • Author(s)
      Chuma Makoto、Hattori Nobuhiro、Watanabe Tsunamasa、Maeda Shin
    • Journal Title

      Hepatology Research

      Volume: 52 Issue: 3 Pages: 269-280

    • DOI

      10.1111/hepr.13732

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08451, KAKENHI-PROJECT-21K07899
  • [Journal Article] Anti-adipogenic and antiviral effects of l-carnitine on hepatitis C virus infection.2016

    • Author(s)
      Tsukuda Y, Suda G, Tsunematsu S, Ito J, Sato F, Terashita K, Nakai M, Sho T, Maehara O, Shimazaki T, Kimura M, Morikawa K, Natsuizaka M, Ogawa K, Ohnishi S, Chuma M, Sakamoto N
    • Journal Title

      J Med Virol

      Volume: 89 Issue: 5 Pages: 857-866

    • DOI

      10.1002/jmv.24692

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08943, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16K15420
  • [Journal Article] ZEB1 expression is associated with prognosis of intrahepatic cholangiocarcinoma2016

    • Author(s)
      Terashita K, Chuma M, Hatanaka Y, Hatanaka K, Mitsuhashi T, Yokoo H, Ohmura T, Ishizu H, Muraoka S, Nagasaka A, Tsuji T, Yamamoto Y, Kurauchi N, Shimoyama N, Toyoda H, Kumada T, Kaneoka Y, Maeda A, Ogawa K, Natsuizaka M, Kamachi H, Kakisaka T, Kamiyama T, Taketomi A, Matsuno Y, Sakamoto N
    • Journal Title

      J Clin Pathol

      Volume: in press Issue: 7 Pages: 593-599

    • DOI

      10.1136/jclinpath-2015-203115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-25460449, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-15K08943, KAKENHI-PROJECT-16K08684
  • [Journal Article] Intratumoral artery on contrast-enhanced computed tomography imaging: differentiating intrahepatic cholangiocarcinoma from poorly differentiated hepatocellular carcinoma2015

    • Author(s)
      Tsunematsu S, Chuma M, Kamiyama T, Miyamoto N, Yabusaki S, Hatanaka K, Mitsuhashi T, Kamachi H, Yokoo H, Kakisaka T, Tsuruga Y, Orimo T, Wakayama K, Ito J, Sato F, Terashita K, Nakai M, Tsukuda Y, Sho T, Suda G, Morikawa K, Natsuizaka M, Nakanishi M, Ogawa K, Taketomi A, Matsuno Y, Sakamoto N
    • Journal Title

      Abdom Imaging

      Volume: 40 Issue: 6 Pages: 1492-9

    • DOI

      10.1007/s00261-015-0352-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-26461021
  • [Journal Article] New molecularly targeted therapies against advanced hepatocellular carcinoma: From molecular pathogenesis to clinical trials and future directions.2015

    • Author(s)
      Chuma M, Terashita K, Sakamoto N
    • Journal Title

      Hepatol Res

      Volume: 印刷中 Issue: 10

    • DOI

      10.1111/hepr.12459

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26460982
  • [Journal Article] Heat shock factor 1 accelerates hepatocellular carcinoma development by activating nuclear factor κB/mitogen-activated protein kinase.2014

    • Author(s)
      Chuma M, Sakamoto N, Nakai A, Hige S, Nakanishi M, Natsuizaka M, Suda G, Sho T, Hatakaka K, Matsuno Y, Yokoo H, Kamiyama T, Taketomi A, Fujii G, Tashiro K, Hikiba Y, Fujimoto M, Asaka M, Maeda S
    • Journal Title

      Carcinogenesis

      Volume: Epub ahead of print Issue: 2 Pages: 272-281

    • DOI

      10.1093/carcin/bgt343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25440010, KAKENHI-PROJECT-25860512, KAKENHI-PROJECT-25860513, KAKENHI-PROJECT-26460982
  • [Journal Article] p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5.2011

    • Author(s)
      Kobayashi T, Ishida J, Musashi M, Ota S, Yoshida T, Shimizu Y, Chuma M, Kawakami H, Asaka M, Tanaka J, Imamura M, Kobayashi M, Itoh H, Edamatsu H, Sutherland LC, Brachmann RK.
    • Journal Title

      Int J Cancer. 128(2)

      Pages: 304-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Journal Article] Sensitive Assay for Quantification of Hepatitis B Virus Mutants by Use of a Minor Groove Binder Probe and Peptide Nucleic Acids.2010

    • Author(s)
      Shubei Hige, Yoichi Yamamoto, Shigeru Yoshida, Tomoe Kobayashi, Hiromasa Horimoto, Keiko Yamamoto, Takuya Sho, Mitsuteru Natsuizaka, Mitsuru Nakanishi, Makoto Chuma, Masahiro Asaka
    • Journal Title

      Journal of Clinical Microbiology. 48

      Pages: 4487-4494

    • NAID

      120003043348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590753
  • [Journal Article] The influence of hepatitis B DNA level and antiviral therapy on recurrence after initial curative treatment in patients with hepatocellular carcinoma.2009

    • Author(s)
      Chuma M, Hige S, Kamiyama T, Meguro T, Nagasaka A, Nakanishi K, Yamamoto Y, Nakanishi M, Kohara T, Sho T, Yamamoto K, Horimoto H, Kobayashi T, Yokoo H, Matsushita M, Todo S, Asaka M.
    • Journal Title

      J Gastroenterol. 44(9)

      Pages: 991-999

    • NAID

      10025581551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Journal Article] The influence of hepatitis B DNA level and antiviral therapy on recurrence afterinitial curative treatment in patients with hepatocellular carcinoma.2009

    • Author(s)
      Chuma M
    • Journal Title

      J Gastroenterol. 23

      Pages: 991-999

    • NAID

      10025581551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Journal Article] 8-OHdG is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection2008

    • Author(s)
      Chuma M
    • Journal Title

      J Gastroenterol Hepatol. 23

      Pages: 1431-1436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Journal Article] 8-OHdG is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.2008

    • Author(s)
      Chuma M, Hige S, Nakanishi M, Ogawa K, Natsuizaka M, Yamamoto Y, Asaka M.
    • Journal Title

      J Gastroenterol Hepatol. 23(9)

      Pages: 1431-1436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Presentation] Safety and efficacy of atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma in early clinical practice: A multicenter analysis.2022

    • Author(s)
      Chuma M, Uojima H, Hattori N, Arase Y, Fukushima T, Hirose S, Hidaka H, Morimoto M, Numata K, Kagawa T, Maeda S
    • Organizer
      30th. United European Gastroenterology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 切除不能肝細胞癌におけるAtezolizumab+Bevacizumabの安全性、有効性に関する多施設共同研究2022

    • Author(s)
      中馬誠, 魚嶋晴紀, 福島泰斗
    • Organizer
      第58回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] Circulating microRNA-1246 as a Possible Biomarker for Early Tumor Recurrence of Hepatocellular Carcinoma.2022

    • Author(s)
      Chuma M, Toyoda H, Yokoo H, Nozaki A, Ogushi K, Tada T, Ogawa K, Numata K, Kumada T, Taketomi A, Naoya S, Maeda S
    • Organizer
      Asian Pacific Association for the Study of the Liver (APASL) Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 肝細胞癌の免疫療法+分子標的治療の実臨床における成績と効果関連バイオマーカーの選定2022

    • Author(s)
      中馬誠, 加川建弘, 豊田秀徳
    • Organizer
      第30回日本消化器関連学会週間 (JDDW2022)
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] Identification of CT Values That Could Be Predictive of Necrosis (N-CTav) in Hepatocellular Carcinoma after Lenvatinib Treatment2022

    • Author(s)
      Chuma M, Yokoo H, Hiraoka A, Ueda K, Tsuji K, Shimada N, Uojima H, Kobayashi S, Hattori N, Okubo T, Atsukawa M, Ishikawa T, Toyoda H, Tada T, Saito Y, Hidaka H, Morimoto M, Numata K, Kagawa T, Sakamoto M, Kumada T
    • Organizer
      30th. United European Gastroenterology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 進行肝癌におけるアテゾリズマブ/ベバシズマブの治療効果、安全性に関する多施設共同研究2021

    • Author(s)
      中馬誠, 森本学, 加川建弘
    • Organizer
      第29回日本消化器関連学会週間 (JDDW2021)
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] 進行肝癌に対するAtezolizumab+Bevacizumabの初期治療成績2021

    • Author(s)
      中馬誠, 魚嶋晴紀, 服部伸洋
    • Organizer
      第57回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-21K07899
  • [Presentation] Molecular Pathogenesis for HCC Development: HSF1 Potential Molecular Target for HCC Therapies2016

    • Author(s)
      Chuma M, Sakamoto N, Yokoo H, Kamiyama T, Taketomi A, Maeda S.
    • Organizer
      The 25th Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-02-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460982
  • [Presentation] 肝細胞癌の早期再発予測に関する血清バイオマーカー2014

    • Author(s)
      中馬 誠、坂本 直哉、神山 俊哉
    • Organizer
      第50回肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-05-30
    • Data Source
      KAKENHI-PROJECT-26460982
  • [Presentation] 肝細胞癌根治後の再発に関するHBV-DNA量、抗ウイルス薬の影響2010

    • Author(s)
      中馬誠
    • Organizer
      第38回日本肝臓学会東部会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Presentation] 肝細胞癌根治後の再発に関するHBV-DNA量、抗ウイルス薬の関与2009

    • Author(s)
      中馬誠
    • Organizer
      第45回日本肝臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Presentation] The Influence of Hepatitis B DNA Level and Antiviral Therapy on Recurrence After Initial Curative Treatment in Patients With Hepatocellular Carcinoma.2009

    • Author(s)
      Chuma M.
    • Organizer
      第19回 アジア太平洋肝臓学会
    • Place of Presentation
      香港
    • Year and Date
      2009-02-15
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Presentation] 8-OHdG is a risk factor for development of hepatocellular carcinoma in natients with chronic hepatitis C virus infection2008

    • Author(s)
      Chuma M
    • Organizer
      第43回欧州肝臓学会
    • Place of Presentation
      イタリア・ミラノ
    • Data Source
      KAKENHI-PROJECT-20590752
  • [Presentation] 8-OHdG is a risk factor for development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection.2008

    • Author(s)
      Chuma M.
    • Organizer
      第43回欧州肝臓学会
    • Place of Presentation
      ミラノ
    • Year and Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-20590752
  • 1.  KOBAYASHI Takahiko (80333607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  HIGE Shuhei (70261295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  坂本 直哉 (10334418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  前田 愼 (40415956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  魚嶋 晴紀 (20752869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 6.  WATANABE Tsunamasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  須田 剛生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  小川 浩司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  近藤 正晃
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  中西 満
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  森川 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  大西 俊介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi