Teruya Kenta 照屋健太

… Alternative Names

照屋健太テルヤケンタ

TERUYA Kenta 照屋健太

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Researcher Number	30372288
Other IDs	https://orcid.org/0000-0002-0500-986X
Affiliation (Current)	2025: 長崎大学, 研究開発推進機構, 戦略職員
Affiliation (based on the past Project Information) *help	2023: 東北大学, 医学系研究科, 准教授 2019 – 2021: 東北大学, 医学系研究科, 准教授 2017: 東北大学, 医学(系)研究科(研究院), 准教授 2016 – 2017: 東北大学, 医学系研究科, 准教授 2015: 東北大学, 医学(系)研究科(研究院), 准教授 … More 2011 – 2013: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2007 – 2008: Tohoku University, 大学院・医学系研究科, 助教 2006: 東北大学, 大学院医学研究科, 助手 2004 – 2006: 東北大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Chemistry related to living body / Basic Section 38030:Applied biochemistry-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Biomolecular chemistry Except Principal Investigator Neurology / Science and Engineering
Keywords	Principal Investigator プリオン / C末端修飾 / プリオン病 / コレステロール / チオエステル / プリオン蛋白質 / スパイン / シグナル伝達 / グリア成熟因子 β / アクチン … More / グリア / 薬剤感受性 / GMFβ / ミクログリア / マウス系統 / T細胞 / セルロースエーテル / 免疫不全マウス / T-cell / prion / preventive treatment / gmfb / drug / cellulose ether / anti-prion / 多量体 / 異常型プリオン蛋白質 / 増感剤 / 光反応 / クロスリンク / 緑色蛍光蛋白質 / ファチジルエタノール / α-チオエステル / 細胞表面 / 蛋白質 / 縮合 / リポソーム / GFP / セグメント縮合 / 選択的化学修飾 / インテイン / 膜結合型蛋白質 / 蛋白質ライゲーション … More Except Principal Investigator 構造活性相関 / Aβ / プリオン / 病態 / 治療 / アミロイド親和性化合物 / アルツハイマー病 / プリオン病 / 治療学 / 神経病態生化学 / 生体機能分子 / 原子レベル分解能 / X線結晶構造解析 / リガンド / アゴニスト / 天然物 / ダイシハーベイン / グルタミン酸受容体 Less

Molecular Mechanisms of Spine Disruption Developed from Mouse Strain Differences in Antiprion Drug SusceptibilityPrincipal Investigator
- Principal Investigator
  
  照屋健太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Tohoku University
Potency of ingredients?Principal Investigator
- Principal Investigator
  
  TERUYA Kenta
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tohoku University
Investigation of interfaces on protein among aggregate on living cellPrincipal Investigator
- Principal Investigator
  
  Teruya Kenta
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tohoku University
Enhancement by liposome of semi-synthesis of specifically modified protein at the C-terminal and application to living cellPrincipal Investigator
- Principal Investigator
  
  TERUYA Kenta
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyoto Prefectural University of Medicine
Research of therapeutic strategy applying to both prion diseases and Alzheimer's disease
- Principal Investigator
  
  DOH-URA Katsumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Tohoku University
グルタミン酸受容体と新規生体機能分子複合体のX線結晶構造解析
- Principal Investigator
  
  海野昌喜
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
化学修飾によって蛋白質を神経細胞表面の特定の部位に局在化させるPrincipal Investigator
- Principal Investigator
  
  照屋健太
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tohoku University
膜結合型プリオン蛋白質の調製法の開発、及び脂質膜への再構成Principal Investigator
- Principal Investigator
  
  照屋健太
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tohoku University

[Journal Article] Design, Synthesis and Evaluation of Catechol-Based Amyloid Beta Aggregation Inhibitors2023
- Author(s)
  Konno Hiroyuki、Teruya Kenta
- Journal Title
  
  HETEROCYCLES
  
  Volume: 106 Issue: 5 Pages: 797-797
- DOI
  10.3987/rev-22-999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05036
[Journal Article] Design of the peptide C-terminus protecting group and application for the peptide fragment coupling reaction2023
- Author(s)
  Okawara Ayaka、Hada Keigo、Kurotani Reiko、Teruya Kenta、Konno Hiroyuki
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 127 Pages: 154665-154665
- DOI
  10.1016/j.tetlet.2023.154665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05036
[Journal Article] Preventive or promotive effects of PRNP polymorphic heterozygosity on the onset of prion disease2023
- Author(s)
  Kai Hideaki、Teruya Kenta、Takeuchi Atsuko、Nakamura Yoshikazu、Mizusawa Hidehiro、Yamada Masahito、Kitamoto Tetsuyuki
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 3 Pages: e13974-e13974
- DOI
  10.1016/j.heliyon.2023.e13974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07531, KAKENHI-PROJECT-23K05036
[Journal Article] 治療法開発状況2023
- Author(s)
  照屋健太、堂浦克美
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 41 Pages: 1240-1243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05036
[Journal Article] Activities of curcumin-related compounds in two cell lines persistently infected with different prion strains2022
- Author(s)
  Teruya Kenta、Iwabuchi Sara、Watanabe Yuki、Tsuchida Rikiya、Watanabe-Matsui Miki、Konno Hiroyuki、Doh-ura Katsumi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1866 Issue: 4 Pages: 130094-130094
- DOI
  10.1016/j.bbagen.2022.130094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K24239
[Journal Article] Anti-prion activity of cellulose ether is impaired in mice lacking pre T-cell antigen receptor α, T-cell receptor δ, or lytic granule function2022
- Author(s)
  Teruya Kenta、Oguma Ayumi、Takahashi Satoko、Watanabe-Matsui Miki、Tsuji-Kawahara Sachiyo、Miyazawa Masaaki、Doh-ura Katsumi
- Journal Title
  
  International Immunopharmacology
  
  Volume: 107 Pages: 108672-108672
- DOI
  10.1016/j.intimp.2022.108672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03481, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K24120, KAKENHI-PROJECT-23K24239
[Journal Article] Therapeutic development of polymers for prion disease.2022
- Author(s)
  Teruya K, Doh-ura K.
- Journal Title
  
  Cell Tissue Res.
  
  Volume: in press. Issue: 1 Pages: 349-365
- DOI
  10.1007/s00441-022-03604-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435, KAKENHI-PROJECT-23K05036, KAKENHI-PROJECT-23K24239
[Journal Article] The Effects of Side-Chain Configurations of a Retro Inverso-Type Inhibitor on the Human T-Cell Leukemia Virus (HTLV)-1 Protease2022
- Author(s)
  Awahara Chiyuki、Oku Daiki、Furuta Saki、Kobayashi Kazuya、Teruya Kenta、Akaji Kenichi、Hattori Yasunao
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 5 Pages: 1646-1646
- DOI
  10.3390/molecules27051646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22479
[Journal Article] Polymorphisms in glia maturation factor β gene are markers of cellulose ether effectiveness in prion-infected mice2021
- Author(s)
  Teruya Kenta、Oguma Ayumi、Arai Keita、Nishizawa Keikoi、Sakasegawa Yuji、Schatzl Hermann、、Iwabuchi Sara、Watanabe-Matsui MikGilch Sabine、Doh-ura Katsumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 560 Pages: 105-111
- DOI
  10.1016/j.bbrc.2021.04.116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435
[Journal Article] Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics2021
- Author(s)
  Ding Mingxuan、Teruya Kenta、Zhang Weiguanliu、Lee Hae Weon、Yuan Jue、Oguma Ayumi、Foutz Aaron、Camacho Manuel V.、Mitchell Marcus、Greenlee Justin J.、Kong Qingzhong、Doh-ura Katsumi、Cui Li、Zou Wen-Quan
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 58 Issue: 9 Pages: 4280-4292
- DOI
  10.1007/s12035-021-02418-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-19H03570, KAKENHI-PROJECT-21K19435
[Journal Article] Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction2019
- Author(s)
  Teruya Kenta、Nishizawa Keiko、Oguma Ayumi、Sakasegawa Yuji、Kitamoto Tetsuyuki、Doh-ura Katsumi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1863 Issue: 2 Pages: 384-394
- DOI
  10.1016/j.bbagen.2018.11.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07518, KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-18H02738, KAKENHI-PROJECT-19K22479
[Journal Article] Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-infected Cells.2019
- Author(s)
  Nishizawa K, Teruya K, Oguma A, Sakasegawa Y, Schatzl H, Gilch S, Doh-ura K.
- Journal Title
  
  J Pharm Sci.
  
  Volume: － Issue: 8 Pages: 2814-2820
- DOI
  10.1016/j.xphs.2019.03.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-19K22479, KAKENHI-PROJECT-18K07518, KAKENHI-PROJECT-19H03570
[Journal Article] Synthesis and evaluation of phenylisoserine derivatives for the SARS-CoV 3CL protease inhibitor2017
- Author(s)
  Konno Hiroyuki、Onuma Takumi、Nitanai Ikumi、Wakabayashi Masaki、Yano Shigekazu、Teruya Kenta、Akaji Kenichi
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Issue: 12 Pages: 2746-2751
- DOI
  10.1016/j.bmcl.2017.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07709, KAKENHI-PROJECT-16H05104, KAKENHI-PROJECT-15K01804
[Journal Article] Insights from Therapeutic Studies for PrP Prion Disease.2017
- Author(s)
  Teruya K, Doh-ura K.
- Journal Title
  
  Cold Spring Harb Perspect Med.
  
  Volume: 7(3) Issue: 3 Pages: a024430-a024430
- DOI
  10.1101/cshperspect.a024430
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
[Journal Article] Melanin or melanin-like substance interacts with the N-terminal portion of prion protein and inhibits abnormal prion protein formation in prion-infected cells.2017
- Author(s)
  Taichi Hamanaka, Keiko Nishizawa, Yuji Sakasegawa, Ayumi Oguma, Kenta Teruya, Hiroshi Kurahashi, Hideyuki Hara, Suehiro Sakaguchi, Katsumi Doh-ura
- Journal Title
  
  Journal of Virology
  
  Volume: 印刷中 Issue: 6
- DOI
  10.1128/jvi.01862-16
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01560, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-26293212, KAKENHI-PROJECT-15K15380, KAKENHI-PROJECT-15K01804
[Journal Article] Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion activity.2017
- Author(s)
  Teruya K, Oguma A, Nishizawa K, Kamitakahara H, Doh-ura K.
- Journal Title
  
  PLoS One.
  
  Volume: 12(9) Issue: 9 Pages: e0185357-e0185357
- DOI
  10.1371/journal.pone.0185357
- NAID
  120006878530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19540, KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
[Journal Article] A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents.2016
- Author(s)
  Teruya K, Oguma A, Nishizawa K, Kawata M, Sakasegawa Y, Kamitakahara H, Doh-ura K.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 12(12) Issue: 12 Pages: e1006045-e1006045
- DOI
  10.1371/journal.ppat.1006045
- NAID
  120005980891
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05317, KAKENHI-PROJECT-15K01804
[Journal Article] Structure-activity analysis and antiprion mechanism of isoprenoid compounds2015
- Author(s)
  Hamanaka T, Nishizawa K, Sakasegawa Y, Teruya K, Doh-ura K.
- Journal Title
  
  Virology
  
  Volume: 486 Pages: 63-70
- DOI
  10.1016/j.virol.2015.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804
[Journal Article] Divergent Synthesis of 2,6-Disubstituted Piperidine Alkaloid, (+)-Spectaline by Palladium-Catalyzed Cyclization2015
- Author(s)
  Katsuyama M, Furuta M, Kobayashi K, Teruya K, Makabe H, Akaji K, Hattori Y.
- Journal Title
  
  HETEROCYCLES
  
  Volume: 91 Issue: 5 Pages: 959-969
- DOI
  10.3987/com-15-13172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804
[Journal Article] Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors2015
- Author(s)
  Hattori Y, Kobayashi K, Deguchi A, Nohara Y, Akiyama T, Teruya K, Sanjoh A, Nakagawa A, Yamashita E, Akaji K
- Journal Title
  
  Bioorganic and Medicinal Chemistry
  
  Volume: 23 Issue: 17 Pages: 5626-5640
- DOI
  10.1016/j.bmc.2015.07.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804, KAKENHI-PROJECT-25460160
[Journal Article] Anti-prion activity found in beetle grub hemolymph of Trypoxylus dichotomus septentrionalis2015
- Author(s)
  Hamanaka T, Nishizawa K, Sakasegawa Y, Kurahashi H, Oguma A, Teruya K, Doh-ura K.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 3 Pages: 332-337
- DOI
  10.1016/j.bbrep.2015.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804
[Journal Article] Secretin Receptor Involvement in Prion-Infected Cells and Animals2015
- Author(s)
  Kimura T, Nishizawa K, Oguma A., Nishimura Y, Sakasegawa Y, Teruya K, Nishijima I, Doh-ura K.
- Journal Title
  
  FEBS Letters
  
  Volume: 589 Issue: 15 Pages: 2011-2018
- DOI
  10.1016/j.febslet.2015.05.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01804, KAKENHI-PROJECT-15K19000, KAKENHI-PROJECT-24590370
[Journal Article] Synthesis of a pyrrolidine analog of a tetrahydrofuran containing acetogenin, cis-solamin2015
- Author(s)
  Ohnishi K, Sakurai H, Katsuyama M, Kobayashi K, Makabe H, Teruya K, Akaji K, Hattori Y.
- Journal Title
  
  HETEROCYCLES
  
  Volume: 91 Issue: 3 Pages: 573-582
- DOI
  10.3987/com-14-13163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804, KAKENHI-PROJECT-25460160
[Journal Article] Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cells2015
- Author(s)
  Teruya K, Wakao M, Sato M, Hamanaka T, Nishizawa K, Funayama Y, Sakasegawa Y, Suda Y, Doh-ura K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 460 Issue: 4 Pages: 989-995
- DOI
  10.1016/j.bbrc.2015.03.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804
[Journal Article] Fused-ring structure of decahydroisoquinolin as a novel scaffold for SARS 3CL protease inhibitors2015
- Author(s)
  Shimamoto Y, Hattori Y, Kobayashi K, Teruya K, Sanjho A, Nakagawa A, Yamashita E, Akaji K.
- Journal Title
  
  Bioorganic and Medicinal Chemistry
  
  Volume: 23 Issue: 4 Pages: 876-890
- DOI
  10.1016/j.bmc.2014.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01804, KAKENHI-PROJECT-25460160
[Journal Article] The influence of PRNP polymorphisms on human prion disease susceptibility: an update2015
- Author(s)
  Kobayashi A, Teruya K, Matsuura Y, Shirai T, Nakamura Y, Yamada M, Mizusawa H, Mohri S, Kitamoto T.
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 130 Issue: 2 Pages: 159-170
- DOI
  10.1007/s00401-015-1447-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01804, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-26670435, KAKENHI-PROJECT-24370046, KAKENHI-PROJECT-25280109
[Journal Article] Evaluating Prion Models Based on Comprehensive Mutation Data of Mouse PrP.2014
- Author(s)
  Shirai T, Saito M, Kobayashi A, Asano M, Hizume M, Ikeda S, Teruya K, Morita M, Kitamoto T.
- Journal Title
  
  Structure.
  
  Volume: 22 Issue: 4 Pages: 560-571
- DOI
  10.1016/j.str.2013.12.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550195, KAKENHI-PROJECT-24370046, KAKENHI-PROJECT-24650185, KAKENHI-PROJECT-25257506, KAKENHI-PROJECT-25280109, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-26670435
[Journal Article] Efficacy and Mechanism of a Glycoside Compound Inhibiting Abnormal Prion Protein Formation in Prion-Infected Cells: Implications of Interferon and Phosphodiesterase 4D-Interacting Protein.2014
- Author(s)
  Nishizawa K, Oguma A, Kawata M, Sakasegawa Y, Teruya K, Doh-Ura K.
- Journal Title
  
  J Virol.
  
  Volume: 88 Issue: 8 Pages: 4083-4099
- DOI
  10.1128/jvi.03775-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23550195, KAKENHI-PROJECT-24659424
[Journal Article] Amyloid-binding compounds and their anti-prion potency2013
- Author(s)
  Teruya K and Doh-ura K
- Journal Title
  
  Current Topics in Medicinal Chemistry
  
  Volume: 13 Pages: 2522-2532
- URL
  http://www.eurekaselect.com/115698/article
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] A Practical Synthesis of a Hydroxylated Sesquiterpene Coumarin 10’R-acetoxy-11’-hydroxyumbelliprenin by the regioselective dihydroxylation2013
- Author(s)
  Hattori Y, Kinami G, Teruya K, Nosaka K, Kobayashi K, Akaji K.
- Journal Title
  
  HETEROCYCLES
  
  Volume: 87 Issue: 2 Pages: 423-428
- DOI
  10.3987/com-12-12636
- NAID
  40019561792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] Amyloid-binding compounds and their anti-prion potency.2013
- Author(s)
  Teruya K, Doh-ura K.
- Journal Title
  
  Curr Top Med Chem.
  
  Volume: 13 Pages: 2522-2532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] Site-specific isotope labeling of long RNA for structural and mechanistic studies.2012
- Author(s)
  3. Kawahara I, Haruta K, Ashihara Y, Yamanaka D, Kuriyama M, Toki N, Kondo Y, Teruya K, Ishikawa J, Furuta H, Ikawa Y, Kojima C, Tanaka Y.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 40 Issue: 1 Pages: e7-e7
- DOI
  10.1093/nar/gkr951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] Epimerization in Peptide Thioester Condensation.2012
- Author(s)
  Teruya K, Tanaka T, Kawakami T, Akaji K, Aimoto S.
- Journal Title
  
  Journal of PEPTIDE SCIENCE
  
  Volume: 18 Issue: 11 Pages: 669-677
- DOI
  10.1002/psc.2452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] Evaluation of superior BACE1 cleavage sequences containing unnatural amino acids2011
- Author(s)
  T. Kakizawa, A. Sanjoh, A. Kobayashi, Y. Hattori, K. Teruya, and K. Akaji
- Journal Title
  
  Bioorganic and Medicinal Chemistry
  
  Volume: 19 Issue: 9 Pages: 2785-2789
- DOI
  10.1016/j.bmc.2011.03.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790119, KAKENHI-PROJECT-23550195
[Journal Article] Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors2011
- Author(s)
  Kenichi. Akaji, et.al.
- Journal Title
  
  J.Med.Chem.
  
  Volume: 54 Issue: 23 Pages: 7962-7973
- DOI
  10.1021/jm200870n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590017, KAKENHI-PROJECT-21689004, KAKENHI-PROJECT-23550195
[Journal Article] Binding and selectivity of the marine toxins neodysiherbaine A, and its synthetic analogues, to GluK1 and GIuK2 kainate receptors2011
- Author(s)
  M.Unno, M.Shinohara, K.Takayama, H.Tanaka, K.Teruya, K.Doh-ura, R.Sakai, M.Sasaki, M.Ikeda-Saito
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 413 Issue: 3 Pages: 667-683
- DOI
  10.1016/j.jmb.2011.08.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21241050, KAKENHI-PROJECT-21350087, KAKENHI-PROJECT-22390172, KAKENHI-PROJECT-22770096, KAKENHI-PLANNED-23102016, KAKENHI-PUBLICLY-23121504, KAKENHI-PROJECT-23550195
[Journal Article] Evaluation of superior BACE1 cleavage sequences containing unnatural amino acids2011
- Author(s)
  Kakizawa T, Sanjoh A, Kobayashi A, Hattori Y, Teruya K, Akaji K
- Journal Title
  
  Bioorganic Medicinal Chemistry
  
  Volume: 19 Pages: 2785-2789
- Data Source
  KAKENHI-PROJECT-23550195
[Journal Article] Amyloidophilic compounds for prion diseases2009
- Author(s)
  Teruya K, Kawagoe K, Kimura T, Chen CJ, Sakasegawa Y, Doh-ura K
- Journal Title
  
  Infect Disord Drug Targets. 9(1)
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Amyloidophilic compounds for prion diseases2009
- Author(s)
  Teruya K, Kawagoe K, Kimura T, Chen CJ, Sakasegawa Y, Doh-ura K
- Journal Title
  
  Infect Disord Drug Targets 9(1)
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Antiprion activity of functionalized 9-aminoacridines related to quinacrine2008
- Author(s)
  Nguyen TH, Lee CY, Teruya K, Ong WY, Doh-ura K, Go ML
- Journal Title
  
  Bioorg Med Chem 16(14)
  
  Pages: 6737-6746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Antiprion activity of functionalized 9-aminoacridines related to quinacrine2008
- Author(s)
  Nguyen TH, Lee CY, Teruya K, Ong WY, Doh-ura K, Go ML
- Journal Title
  
  Bioorg Med Chem. 16(14)
  
  Pages: 6737-6746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Conformational Changes in Hamster Scrapie Prion Protein (PrP27-30) Associated with Proteinase K Resistance and Prion Infectivity.2008
- Author(s)
  Suzuki SY, Tanaka M, Teruya K, Shinagawa M, Mohri S and Yokoyama T.
- Journal Title
  
  International Journal of Veterinary Medical Science 70
  
  Pages: 159-165
- NAID
  130000447074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Spectroscopic and Theoretical Studies of Biological Macromolecules toward Understanding Molecular Machinaries in Life2007
- Author(s)
  Tanaka Y, Morita EH, Teruya K, Kodama TS and Tanaka T.
- Journal Title
  
  Recent Research Development in Physical Chemistry 9
  
  Pages: 1-59
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Studies on Substrate Specificity at PR/p3 Cleavage Site of HTLV-1 Protease2007
- Author(s)
  Bang JK, Teruya K, Aimoto S, Konno H, Nosaka K, Tatsumi T and Akaji K.
- Journal Title
  
  International Journal of Peptide Research and Therapeutics 13
  
  Pages: 173-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Orally administered amyloidphilic compound is effective in prolonging the incubation periods of cerebrally infected prion disease animals in a prion strain-dependent manner2007
- Author(s)
  Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y and Doh-ura K.
- Journal Title
  
  Journal of Virology 81
  
  Pages: 12889-12898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner.2007
- Author(s)
  Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y, Doh-Ura K
- Journal Title
  
  J. Virol. 81(23)
  
  Pages: 12889-12898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner2007
- Author(s)
  Kawasaki Y, Kawagoe K, Chen CJ, Teruya K, Sakasegawa Y, Doh-Ura K
- Journal Title
  
  J. Virol 81(23)
  
  Pages: 12889-12898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390234
[Journal Article] Evaluations of Substrate Specificity and Inhibition at PR/p3 Cleavage Site of HTLV-1 Protease2006
- Author(s)
  Naka H, Teruya K, Bang JK, Aimoto S, Tatsumi T, Konno H, Nosaka K, Akaji K.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters 16
  
  Pages: 3761-3761
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Recent Progress of Thioester Method2006
- Author(s)
  Aimoto S, Teruya K, Hasegawa K, Sato T, Akaji K, Kawakami T.
- Journal Title
  
  Chemical Research in Chinese University 22
  
  Pages: 253-253
- Data Source
  KAKENHI-PROJECT-18750139
[Journal Article] Solid-Phase Syntheses of Olefin-Containing Inhibitors for HTLV-1 Protease Using the Horner-Emmons Reaction2005
- Author(s)
  Bang JK, Naka H, Teruya K, Aimoto S, Konno H, Nosaka K, Tastumi T, Akaji K
- Journal Title
  
  Journal of Organic Chemistry 70
  
  Pages: 10596-10596
- Data Source
  KAKENHI-PROJECT-16750138
[Patent] コンフォメーション病医薬組成物及びその製造方法2016
- Inventor(s)
  堂浦克美、照屋健太、西澤桂子、小熊歩
- Industrial Property Rights Holder
  国立大学法人東北大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-09
- Data Source
  KAKENHI-PROJECT-15K01804
[Patent] プリオン病治療薬及びそのスクリーニング方法。2007
- Inventor(s)
  堂浦克美、照屋健太、隅田泰生
- Industrial Property Rights Holder
  国立大学法人東北大学、国立大学法人鹿児島大学
- Industrial Property Number
  2007-102005
- Filing Date
  2007-04-09
- Data Source
  KAKENHI-PROJECT-18750139
[Patent] 異常型プリオン蛋白質濃縮方法、および除去方法。2007
- Inventor(s)
  堂浦克美、照屋健太、竹中繁織、大塚圭一
- Industrial Property Rights Holder
  国立大学法人東北大学、国立大学法人九州工業大学
- Acquisition Date
  2007-09-27
- Data Source
  KAKENHI-PROJECT-18750139
[Patent] 電気化学的抗原検出法とそのための装置並びに検出チップ。2007
- Inventor(s)
  竹中繁織、大塚圭一、堂浦克美、照屋健太
- Industrial Property Rights Holder
  国立大学法人九州工業大学、国立大学法人東北大学
- Acquisition Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18750139
[Patent] プリオン病治療薬及びそのスクリーニング方法。2007
- Inventor(s)
  堂浦克美、照屋健太、隅田泰生
- Industrial Property Rights Holder
  東北大学、鹿児島大学
- Industrial Property Number
  2007-102005
- Filing Date
  2007-04-09
- Data Source
  KAKENHI-PROJECT-19390234
[Patent] プリオン治療薬及びそのスクリーニング方法2007
- Inventor(s)
  堂浦克美, 照屋健太, 隅田泰生
- Industrial Property Rights Holder
  東北大学, 鹿児島大学
- Industrial Property Number
  2007-102005
- Filing Date
  2007-04-09
- Data Source
  KAKENHI-PROJECT-19390234
[Patent] 電気化学的抗原検出法とそのための装置並びに検出チップ2006
- Inventor(s)
  竹中繁織, 大塚圭一, 堂浦克美, 照屋健太
- Industrial Property Rights Holder
  九州工業大学, 東北大学
- Industrial Property Number
  2006-065744
- Filing Date
  2006-03-10
- Data Source
  KAKENHI-PROJECT-18750139
[Patent] 異常型プリオン蛋白質濃縮方法、および除去方法2006
- Inventor(s)
  堂浦克美, 照屋健太, 竹中繁織, 大塚圭一
- Industrial Property Rights Holder
  東北大学, 九州工業大学
- Industrial Property Number
  2006-071881
- Filing Date
  2006-03-15
- Data Source
  KAKENHI-PROJECT-18750139
[Presentation] Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on Acquired and Spontaneous Prion Diseases in Humanized Transgenic Mice2023
- Author(s)
  Wang Z, Binyamin O, Martinez MC, Gilliland T, Teruya K, Gerasimenko M, Doh-ura K, Gabizon R, Kong Q, Zou WQ
- Organizer
  PRION 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05036
[Presentation] Prophylactic and Therapeutic Efficacy of a Cellulose Ether Compound TC-5RW on Acquired and Spontaneous Prion Diseases in Humanized Transgenic Mice2023
- Author(s)
  Wang Z, Binyamin O, Martinez MC, Gilliland T, Teruya K, Gerasimenko M, Doh-ura K, Gabizon R, Kong Q, Zou WQ
- Organizer
  Asia Pacific Prion Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05036
[Presentation] Preparation of SAR-CoV-2 3CL protease and investigation of its substrate recognition.2023
- Author(s)
  Endo R, Sano H, Yokomichi M, Makabe K, Yano S, Hattori Y, Teruya K Konno H
- Organizer
  第60回ペプチド討論会(2023)
- Data Source
  KAKENHI-PROJECT-23K05036
[Presentation] Candidate drugs for treatment of prion diseases.2023
- Author(s)
  Kenta Teruya
- Organizer
  Asia Pacific Prion Symposium 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05036
[Presentation] Fragment coupling reaction of protected peptides using ψ-wang and its vinyl handles2021
- Author(s)
  Ayaka Okawara, Mariko Kikuchi, Reiko Kurotani, Kenta Teruya, and Hiroyuki Konno
- Organizer
  第58回ペプチド討論会(2021)
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] プリオン病治療薬開発の現状2021
- Author(s)
  照屋健太
- Organizer
  第62回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Photoreaction-induced SDS-resistant PrPSc/res oligomer formation2021
- Author(s)
  Kenta Teruya, Toshiya Ishikawa, Sara Iwabuchi, Miki Watanabe-Matsui, Katsumi Doh-ura
- Organizer
  第58回ペプチド討論会(2021)
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Characterization of The Effects of Curcumin Related Compounds on Two Prion Strains2020
- Author(s)
  岩渕サラ、照屋健太、松井美樹、今野博之、堂浦克美
- Organizer
  第57回ペプチド討論会(2020)
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Prophylactic Anti-prion Effects of Cellulose Ether Compounds Depend on Host Mouse Strains2020
- Author(s)
  照屋健太、西澤桂子、小熊歩、堂浦克美
- Organizer
  第57回ペプチド討論会(2020)
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Protection to prion infection by cellulose ether compounds depends on host mouse strains.2019
- Author(s)
  Kenta Teruya, Keiko Nishizawa, Ayumi Oguma, Yuji Sakasegawa, Hiroshi Kamitakahara, Katsumi Doh-ura
- Organizer
  Asia Pacific Prion Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Design, Synthesis and Evaluation of SARS 3CL Protease Inhibitors2019
- Author(s)
  大沼拓巳、若林雅貴、矢野成和、照屋健太、赤路健一、今野博行
- Organizer
  第30回記念万有仙台シンポジウム
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Cellulose ether liposomal for the inhibition of prion formation.2019
- Author(s)
  Keiko Nishizawa, Kenta Teruya, Ayumi Oguma, Yuji Sakasegawa, Hiroshi Kamitakahara, Katsumi Doh-ura
- Organizer
  Asia Pacific Prion Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22479
[Presentation] Cellulose ether compounds exert protection to prion infection; a biological parameter related to the effectiveness of compounds2017
- Author(s)
  Katsumi Doh-ura, Kenta Teruya, Keiko Nishizawa, Ayumi Oguma, Yuji Sakasegawa, Hiroshi Kamitakahara
- Organizer
  Asia Pacific Prion Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Anti-prion activities of cellulose ether compounds in prion-infected cells are consistent with long-lasting anti-prion activities in vivo.2017
- Author(s)
  Keiko Nishizawa, Kenta Teruya, Ayumi Oguma, Yuji Sakasegawa, Katsumi Doh-ura
- Organizer
  Asia Pacific Prion Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Pyrene index of hydroxypropyl methylcellulose compounds correlates with the in vivo long-lasting anti-prion activity2017
- Author(s)
  Kenta Teruya, Ayumi Oguma, Keiko Nishizawa, Hiroshi Kamitakahara, Katsumi Doh-ura
- Organizer
  Asia Pacific Prion Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Current Therapeutic Development for Prion Disease2017
- Author(s)
  Kenta Teruya
- Organizer
  第60回神経化学大会サテライトシンポジウム「Protein Misfolding Disease and Therapy 2017」
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] デカヒドロイソキノリン骨格を基盤とする新規縮環構造型SARS 3CL protease阻害の設計と合成2017
- Author(s)
  大西康司、嶋本康広、小林数也、服部恭尚、照屋健太、赤路健一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市(仙台国際センター )
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Current Therapeutic Development for Prion Disease2017
- Author(s)
  照屋健太
- Organizer
  第25回山形分子生物学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] プリオン病治療法開発の現状:わが国と海外2017
- Author(s)
  照屋健太
- Organizer
  2016年度　プリオン病のサーベイランスと対策に関する全国担当者会議
- Place of Presentation
  東京都千代田区(アルカディア市ヶ谷)
- Invited
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] ウイルス感染症の新規治療薬開発を目指した標的蛋白質阻害剤複合体の構造生物学研究2017
- Author(s)
  三城明、照屋健太、赤路健一
- Organizer
  第6回名大シンクロトロン光研究センターシンポジウム
- Place of Presentation
  名古屋市(名古屋大学野依記念学術交流館)
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] SELECTIVE PRPSC CROSSLINKING REACTION DETECTED BY WESTERN BLOTTING2016
- Author(s)
  Kenta Teruya, Katsumi Doh-ura
- Organizer
  第53回ペプチド討論会
- Place of Presentation
  京都市(京都テルサ)
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] SARS 3CL プロテアーゼ阻害剤を目指したイソセリン誘導体の合成と評価2016
- Author(s)
  今野博行、若林雅貴、似内郁美、照屋健太、赤路健一
- Organizer
  農芸化学会東北支部会
- Place of Presentation
  山形市(山形大学農学部（鶴岡キャンパス）)
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] A case study of development of inhibitor to a disease related enzyme based on structural and chemometrical analysis2016
- Author(s)
  Kenta Teruya, Yasunao Hattori, Akira Sanjoh, Eiki Yamashita, Atsushi Nakagawa, Kenichi Akaji
- Organizer
  42nd Naito Conference “In the Vanguard of Structural Biology: Revolutionizing Life Sciences”
- Place of Presentation
  札幌市(シャトレーゼガトーキングダムサッポロ)
- Year and Date
  2016-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Effects of cell growth suppression treatments on PrPSc accumulation in prion-infected cells; Paradoxical phenomena observed in butyric acid treatment2016
- Author(s)
  Takako Hiyoshi, Yuji Sakasegawa, Keiko Nishizawa, Kenta Teruya, Katsumi Doh-ura
- Organizer
  PRION 2016 conjugation with Asian Pacific Prion Symposium 2016
- Place of Presentation
  東京都千代田区(一ツ橋ホール)
- Year and Date
  2016-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Dimer sized PrPSc formation detected by western blotting.2016
- Author(s)
  Kenta Teruya, Katsumi Doh-ura
- Organizer
  PRION 2016 conjugation with Asian Pacific Prion Symposium 2016
- Place of Presentation
  東京都千代田区(一ツ橋ホール)
- Year and Date
  2016-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] デカヒドロイソキノリン骨格を基盤とする新規縮環型SARS 3CLプロテアーゼの設計・合成と複合体構造解析2016
- Author(s)
  大西康司、服部恭尚、小林数也、嶋本康広、照屋健太、三城明、赤路健一
- Organizer
  第４６回　複素環化学討論会
- Place of Presentation
  金沢市(金沢歌劇座)
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] A CHEMOMETRICAL ANALYSIS OF STRUCTURES OF SARS 3CL PROTEASE COMPLEXED WITH INHIBITOR2015
- Author(s)
  照屋健太、服部恭尚、嶋本康広、小林数也、三城明、山下栄樹、中川敦史、赤路健一
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  神奈川県平塚市, 平塚中央公民館
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] Evaluation of Hydroxymethylcarbonyl and Hydroxyethylamine Isosteres in a Superior BACE 1 Cheavage Sequence for BACE1 Inhibitors.2015
- Author(s)
  Kazuya Kobayashi, Yasunao Hattori, Ayaka Deguchi, Yukie Nohara, Tomomi Akiyama, Kenta Teruya, Akira Sanjoh, Atsushi Nakagawa, Eiki Yamashita, Kenichi Akaji
- Organizer
  7th International Peptide Symposium
- Place of Presentation
  Republic of Singapore, Singapore
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01804
[Presentation] アイソザイム選択的なJHDM阻害薬の創製2014
- Author(s)
  澤田英之、伊藤幸裕、照屋健太、水上民夫、鈴木孝禎
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Evaluation of Hydroxymethylcarbonyl- and Hydroxyethylamine-type BACE1 Inhibiors Containing a Superior BACE1 Cleavage Sequence.2013
- Author(s)
  Kazuya Kobayashi, Tomomi Akiyama, Yukie Nohara, Saki Goto, Mami Okabe, Natsumi Sato, Miki Itoh, Kanami Ueno, Yasunao Hattori, Kenta Teruya, Akira Sanjho, Kenichi Akaji.
- Organizer
  4th Asia-Pacific International Peptide Symposium (APIPS)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] ヒドロキシメチルカルボニル型及びヒドロキシエチルアミン型BACE1阻害剤の合成と活性評価2013
- Author(s)
  小林数也、秋山朋美、野原由江、後藤紗希、岡部真実、佐藤夏美、伊藤美紀、上野佳奈美、服部恭尚、照屋健太、三城明、中川敦史、山下栄樹、赤路健一
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] ヒドロキシエチル型BACE1阻害剤の設計と立体選択的合成2013
- Author(s)
  野原由江、秋山明美、佐藤夏美、岡部真美、小林数也、服部恭尚、照屋健太、今野博行、赤路健一
- Organizer
  日本薬学会　第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] ヒドロキシエチル型BACE1阻害剤の設計と立体選択的合成2013
- Author(s)
  野原由江、秋山明美、佐藤夏美、岡部真美、小林数也、服部恭尚、照屋健太、今野博行、赤路健一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] ヒドロキシメチルカルボニル型及びヒドロキシエチルアミン型BACE1阻害剤の合成と活性評価2013
- Author(s)
  小林数也、秋山朋美、野原由江、後藤紗希、岡部真実、佐藤夏美、伊藤美紀、上野佳奈美、服部恭尚、照屋健太、三城明、中川敦史、山下栄樹、赤路健一
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] BACE1高認識切断配列を含むヒドロキシエチル型阻害剤の合成2012
- Author(s)
  秋山朋美,後藤紗希,山口充,小林数也,相馬洋平,服部恭尚,照屋健太,今野博行,赤路健一
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Ti(IV)を用いた還元的アミノ化反応による置換基導入を行ったヒドロキシエチルアミン骨格の合成2012
- Author(s)
  野原由江,岡部真実,小林数也,服部恭尚,照屋健太,今野博行,赤路健一
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] SARS 3CLプロテアーゼ・阻害剤複合体の構造解析2012
- Author(s)
  照屋健太、尾崎健、今野博之、服部恭尚、楠木正巳、三城明、赤路健一
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Interactions of prion protein2012
- Author(s)
  照屋健太
- Organizer
  たんぱく研セミナー「ペプチド・蛋白質合成の未来像」
- Place of Presentation
  吹田市
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Syntheses of Hydroxyethylamine Derivatives Containing Side-Chain Mimetic and Peptide Sequence for BACE1 inhibitor2012
- Author(s)
  Hattori, Y.; Akiyama, T.; Nohara, Y.; Nishizaki, A.; Deguchi, A.; Shimamoto, Y.; Teruya, K.; Konnno, H.; Akaji, K.
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] 複合体構造に基づくペプチド型SARS 3CLプロテアーゼ阻害剤の設計・合成と活性評価2012
- Author(s)
  服部恭尚,今野博行,照屋健太,三城明,尾崎健,楠木正己,赤路健一
- Organizer
  メディシナルケミストリーシンポジウム2012年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] C末端を疎水性化合物で修飾したタンパク質へのリポソームの選択的な結合2011
- Author(s)
  遠藤祐里奈・服部恭尚・赤路健一・照屋健太
- Organizer
  第48回ペプチド討論会(2011)
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] BACE1阻害剤を指向した置換ヒドロキシエチルアミン型プロテアーゼ阻害剤の合成と評価2011
- Author(s)
  服部恭尚,西崎綾,出口綾香,嶋本康弘,照屋健太,三城明,今野博行,赤路健一
- Organizer
  第37回反応と合成の進歩シンポジウム
- Place of Presentation
  徳島市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Characterization of the interaction between prion protein and heparin2008
- Author(s)
  Teruya K, Yamada Y, Nishimura T, Suda Y, Doh-ura K
- Organizer
  Prion2007
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] 抗プリオン活性を有するアミロイド親和性化合物の構造的特徴2008
- Author(s)
  濱中大一, 川越敬一, 陳忠正, 照屋健太, 堂浦克美
- Organizer
  2008年プリオン研究会
- Place of Presentation
  新得(北海道)
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] Binding of mouse prion protein to heparin2008
- Author(s)
  Teruya K, Wakao T, Nishimura T, Kimura Y, Sakasegawa Y, Suda Y, Doh-ura K
- Organizer
  Meeting of 17th Methods in Protein Structure Analysis(MPSA2008)
- Place of Presentation
  Sapporo, August(26-29)
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] Binding of mouse prion protein to heparin2008
- Author(s)
  Teruya K, Wakao T, Nishimura T, Kimura Y, Sakasegawa Y, Suda Y, Doh-ura K
- Organizer
  Meeting of 17th Methods in Protein Structure Analysis (MPSA2008)
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析2007
- Author(s)
  篠原正将, 海野昌喜, 照屋健太, 酒井隆一, 堂浦克美, 佐々木誠, 齋藤正男
- Organizer
  第22回生体機能関連化学シンポジウム「若手フォーラム」
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] 銅イオンにより誘起されるプリオンタンパク質の構造変化2007
- Author(s)
  山口恭史, 三浦隆史, 照屋健太, 堂浦克美, 竹内英夫
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] C 末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合。2007
- Author(s)
  照屋健太、山田有希、西澤桂子、堂浦克美
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション2007
- Author(s)
  照屋健太, 山田有希, 隅田泰生, 堂浦克美
- Organizer
  2007年プリオン研究会
- Place of Presentation
  津南(新潟)
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] Characterization of the interaction between prion protein and heparin.2007
- Author(s)
  Teruya K, Yamada Y, Nishimura T, Suda Y, Doh-ura K
- Organizer
  Prion2007
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヒト由来のグルタミン酸受容体GluR5リガンド結合部位の結晶構造解析。2007
- Author(s)
  篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木誠、齋藤正男
- Organizer
  第22回生体機能関連化学シンポジウム「若手フオーラム」
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション。2007
- Author(s)
  照屋健太、山田有希、隅田泰生、堂浦克美
- Organizer
  2007年プリオン研究会
- Place of Presentation
  津南(新潟)
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] プリオン感染細胞からの迅速なPrPres回収法2007
- Author(s)
  照屋健太
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18750139
[Presentation] プリオン感染細胞からの迅速なPrPres回収法2007
- Author(s)
  照屋健太, 魚本幸, 藤田智司, 堂浦克美
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] 銅イオンにより誘起されるプリオンタンパク質の構造変化。2007
- Author(s)
  山口恭史、三浦隆史、照屋健太、堂浦克美、竹内英夫
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] プリオン感染細胞からの迅速なPrPres回収法。2007
- Author(s)
  照屋健太、魚本幸、藤田智司、堂浦克美
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] C末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合2007
- Author(s)
  照屋健太
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山県富山市
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-18750139
[Presentation] Characterization of the Interaction between Prion Protein and Heparin2007
- Author(s)
  Kenta Teruya
- Organizer
  Neuro Prion 2007
- Place of Presentation
  Edinburgh, Scotland, UK
- Year and Date
  2007-09-27
- Data Source
  KAKENHI-PROJECT-18750139
[Presentation] ヘパリンとプリオン蛋白質相互作用のキャラクタリゼーション2007
- Author(s)
  照屋健太
- Organizer
  プリオン研究会2007
- Place of Presentation
  新潟県魚沼郡
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-18750139
[Presentation] C 末端をコレステロールで修飾した蛋白質の半合成と細胞膜への結合2007
- Author(s)
  照屋健太, 山田有希, 西澤桂子, 堂浦克美
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山市
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析。2007
- Author(s)
  篠原正将、海野昌喜、照屋健太、酒井隆一、堂浦克美、佐々木誠、齋藤正男
- Organizer
  第80回目本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] ヒト由来のグルタミン酸受容体GluR5 リガンド結合部位の結晶構造解析2007
- Author(s)
  篠原正将, 海野昌喜, 照屋健太, 酒井隆一, 堂浦克美, 佐々木誠, 齋藤正男
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390234
[Presentation] Evaluation of Hydroxymethylcarbonyl- and Hydroxyethylamine-type BACE1 Inhibiors Containing a Superior BACE1 Cleavage Sequence
- Author(s)
  Kazuya Kobayashi, Tomomi Akiyama, Yukie Nohara, Saki Goto, Mami Okabe, Natsumi Sato, Miki Itoh, Kanami Ueno, Yasunao Hattori, Kenta Teruya, Akira Sanjho, Kenichi Akaji
- Organizer
  4th Asia-Pacific International Peptide Symposium (APIPS)
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Interactions of prion protein
- Author(s)
  照屋健太
- Organizer
  大阪大学蛋白研セミナーペプチド・蛋白質合成の未来像(招待講演)
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23550195
[Presentation] Selective liposome binding of protein modified with hydrophobic compounds at the C-terminal
- Author(s)
  Endo, Yurina; Hattori, Yasunao; Akaji, Kenichi; Teruya, Kenta
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-23550195

1. SAKASEGAWA Yuji (90418616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. DOH-URA Katsumi (00263012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
3. 海野昌喜 (10359549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 齋藤正男 (70302239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KAKIZAWA Taeko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NISHIZAWA Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. OGUMA Ayumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. TAKEUCHI Atsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 今野博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 赤路健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 坂口末廣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 佐々木誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Teruya Kenta 照屋 健太

照屋 健太 テルヤ ケンタ

TERUYA Kenta 照屋 健太

Research Projects

Research Products

Co-Researchers

Molecular Mechanisms of Spine Disruption Developed from Mouse Strain Differences in Antiprion Drug SusceptibilityPrincipal Investigator

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Potency of ingredients?Principal Investigator

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Investigation of interfaces on protein among aggregate on living cellPrincipal Investigator

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Enhancement by liposome of semi-synthesis of specifically modified protein at the C-terminal and application to living cellPrincipal Investigator

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Research of therapeutic strategy applying to both prion diseases and Alzheimer's disease

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グルタミン酸受容体と新規生体機能分子複合体のX線結晶構造解析

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化学修飾によって蛋白質を神経細胞表面の特定の部位に局在化させるPrincipal Investigator

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膜結合型プリオン蛋白質の調製法の開発、及び脂質膜への再構成Principal Investigator

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[Journal Article] Design, Synthesis and Evaluation of Catechol-Based Amyloid Beta Aggregation Inhibitors2023

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[Journal Article] Design of the peptide C-terminus protecting group and application for the peptide fragment coupling reaction2023

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[Journal Article] Preventive or promotive effects of PRNP polymorphic heterozygosity on the onset of prion disease2023

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[Journal Article] 治療法開発状況2023

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[Journal Article] Activities of curcumin-related compounds in two cell lines persistently infected with different prion strains2022

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[Journal Article] Anti-prion activity of cellulose ether is impaired in mice lacking pre T-cell antigen receptor α, T-cell receptor δ, or lytic granule function2022

Author(s)

Teruya Kenta 照屋健太

照屋健太テルヤケンタ

TERUYA Kenta 照屋健太