Yajima Hiroaki 矢島孔明

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YAJIMA Hiroaki 矢島孔明

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Researcher Number	30376412
Other IDs
Affiliation (Current)	2022: 人間総合科学大学, 人間科学部, 教授
Affiliation (based on the past Project Information) *help	2015: 東京大学, 大学院医学系研究科, 特任研究員 2010: 東京大学, 大学院・医学系研究科, 特任研究員
Review Section/Research Field	Except Principal Investigator Biological Sciences
Keywords	Except Principal Investigator 分子モーター / キネシン / 細胞内輸送 / 微小管 / 細胞内物質輸送 / モーター蛋白 / 分子細胞生物学 / 分子遺伝学 / 構造生物学 / キネシンモーター分子群 … More / 統合生物学 / リン酸化 / KIF16B / KIF3 / KIF2A / MAP1A / KIFs / クライオ電子顕微鏡 / 高脂血症 / 癲癇 / 不安神経症 / 線毛 Less

Integrative biological research on function and regulation of Kinesin superfamily molecular motors
- Principal Investigator
  
  HIROKAWA Nobutaka
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The Mechanism of Intracellular Transport and Kinesin Motors, KIFs : Structure, Function, Dynamics and Regulation
- Principal Investigator
  
  HIROKAWA Nobutaka
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.2015
- Author(s)
  Morikawa, M., H. Yajima, R. Nitta, S. Inoue, T. Ogura, C. Sato, and N. Hirokawa
- Journal Title
  
  Neuron
  
  Volume: 34 Pages: 1022-1035
- DOI
  10.15252/embj.201490588
- Description
  (in press)
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J05975, KAKENHI-PROJECT-23000013, KAKENHI-PROJECT-15K08168, KAKENHI-PROJECT-15K14499, KAKENHI-PROJECT-15H04365, KAKENHI-PROJECT-25650057
[Journal Article] New simulated annealing approach considering helix bending applied to determine the 8.8 A structure of 15-protofilament microtubules2015
- Author(s)
  T.Ogura, H. Yajima, R.Nitta, N.Hirokawa, C.Sato
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 188 Pages: 165-176
- DOI
  10.1016/j.jsb.2014.08.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22121004, KAKENHI-PROJECT-23000013, KAKENHI-PROJECT-24370070
[Journal Article] Mutual conformational changes of kinesin and GTP-microtubule upon their binding.2014
- Author(s)
  Morikawa M., H. Yajima, R. Nitta, S. Inoue, T. Ogura, C. Saito and N. Hirokawa
- Journal Title
  
  Develomental Cell
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000013
[Journal Article] Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy.2012
- Author(s)
  Yajima, H., T. Ogura, R. Nitta, Y. Okada, C. Sato, and N. Hirokawa.
- Journal Title
  
  J. Cell. Biol.
  
  Volume: 198 Pages: 315-322
- DOI
  10.1083/jcb.201201161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000013, KAKENHI-PLANNED-22121004
[Presentation] キネシンーGTP型微小管複合体の構造解析2015
- Author(s)
  森川真夏、矢島孔明、仁田亮、井上茂之、小椋俊彦、佐藤主税、廣川信隆
- Organizer
  日本顕微鏡学会第71回学術講演会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Mutual conformational changes of kinesin and GTP microtubule upon their binding2014
- Author(s)
  Morikawa M., Yajima H., Nitta R., Inoue S., Ogura T., Sato C., & Hirokawa N.
- Organizer
  ASCB/ISCB Annual Meeting 2014
- Place of Presentation
  Philadelphia convention center, Philadelphia, USA
- Year and Date
  2014-12-09
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] クライオ電顕を用いたGTP型/GDP-taxol型微小管におけるtubulinの構造変化2013
- Author(s)
  矢島孔明, 小椋俊彦, 仁田亮, 岡田康志, 佐藤主税, 廣川信隆
- Organizer
  第１１８回日本解剖学会・全国学術集会
- Place of Presentation
  香川県高松市
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Conformational Changes in Tubulin in GMPCPP and GDP-taxol Microtubules Observed by Cryo Electron Microscopy2013
- Author(s)
  Hiroaki Yajima, Toshihiko Ogura, Ryo Nitta, Yasushi Okada, Chikara Sato, Nobutaka Hirokawa
- Organizer
  Nagoya Symposium, Frontiers in Structural Physiology
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] ＧＴＰ結合状態とＧＤＰ結合状態の微小管分子構造における大きな構造変化2012
- Author(s)
  矢島孔明, 小椋俊彦, 仁田亮, 岡田康志, 佐藤主税, 廣川信隆
- Organizer
  第５０回日本生物物理学会
- Place of Presentation
  名古屋大学（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-23000013
[Presentation] Conformational Changes in Tubulin in GMPCPP and GDP-taxol Microtubules Observed by Cryo Electron Microscopy2012
- Author(s)
  Hiroaki Yajima, Toshihiko Ogura, Ryo Nitta, Yasushi Okada, Chikara Sato, Nobutaka Hirokawa
- Organizer
  2012 Annual Meeting of The American Society for Cell Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23000013

1. KANAI Yoshimitsu (80214427)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. TAKEI Yosuke (20272487)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. OKADA Yasushi (50272430)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. HIROKAWA Nobutaka (20010085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKATA Takao (50218004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NODA Yasuko (50262019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANAKA Yosuke (90302661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NITTA Ryo (40345038)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. HOMMA Noriko (50345039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MIKI Harukata (10361461)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. OGAWA Tadayuki (40436572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. OGURA Toshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 広川信隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
14. 佐藤主税

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yajima Hiroaki 矢島 孔明

YAJIMA Hiroaki 矢島 孔明

Research Projects

Research Products

Co-Researchers

Integrative biological research on function and regulation of Kinesin superfamily molecular motors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Mechanism of Intracellular Transport and Kinesin Motors, KIFs : Structure, Function, Dynamics and Regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding.2015

Author(s)

Journal Title

DOI

Description

Data Source

[Journal Article] New simulated annealing approach considering helix bending applied to determine the 8.8 A structure of 15-protofilament microtubules2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutual conformational changes of kinesin and GTP-microtubule upon their binding.2014

Author(s)

Journal Title

Data Source

[Journal Article] Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] キネシンーGTP型微小管複合体の構造解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Mutual conformational changes of kinesin and GTP microtubule upon their binding2014

Author(s)

Organizer

Place of Presentation

Year and Date

Description

Data Source

[Presentation] クライオ電顕を用いたGTP型/GDP-taxol型微小管におけるtubulinの構造変化2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Conformational Changes in Tubulin in GMPCPP and GDP-taxol Microtubules Observed by Cryo Electron Microscopy2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ＧＴＰ結合状態とＧＤＰ結合状態の微小管分子構造における大きな構造変化2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Conformational Changes in Tubulin in GMPCPP and GDP-taxol Microtubules Observed by Cryo Electron Microscopy2012

Author(s)

Organizer

Place of Presentation

Data Source

Yajima Hiroaki 矢島孔明

YAJIMA Hiroaki 矢島孔明