otani kaori 大谷郁

… Alternative Names

OHTANI Kaori 大谷郁

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Researcher Number	30377410
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Affiliation (Current)	2025: 一般財団法人マリンオープンイノベーション機構, 研究所, 研究員
Affiliation (based on the past Project Information) *help	2017 – 2022: 東海大学, 医学部, 准教授 2017: 金沢大学, 医学系, 研究員 2015 – 2016: 金沢大学, 医学系, 協力研究員 2015: 金沢大学, 医学系, 研究員 2012 – 2014: 金沢大学, 医学系, 講師 … More 2008 – 2009: 金沢大学, 医学系, 講師 2006 – 2007: 金沢大学, 医学系研究科, 講師 2004 – 2005: Kanazawa University, Graduate School of Medical Science, Bacteriology, Assistant, 医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Bacteriology (including mycology) / Bacteriology (including Mycology) Except Principal Investigator Applied microbiology / Bacteriology (including Mycology) / Infectious disease medicine / Biological Sciences
Keywords	Principal Investigator ウェルシュ菌 / 芽胞 / 異種細菌間コミュニケーション / 環境感知 / 遺伝子発現 / 調節RNA / 遺伝子発現調節 / 発現調節条件 / 毒素産生調節 / RNA … More / 芽胞形成シグナル / 二成分制御系 / 芽胞形成効率 / 芽胞形成 / 異種間情報伝達 / 国際情報交換　オーストラリア / オーストラリア　国際情報交換 / 遺伝子発現調節機構 / 毒素産生 / 発現調節ネットワーク / 細胞間情報伝達 / マイクロアレイ / 毒素産生調節機構 … More Except Principal Investigator ウェルシュ菌 / アンタゴニスト / グラム陽性細菌 / クオラムセンシング / DNAマイクロアレイ / 遺伝子発現調節 / 病原性 / 遺伝子発現制御 / 感染症 / 急性呼吸窮迫症候群 / サイトカイン / θトキシン / 溶血毒 / 血管内溶血 / 敗血症 / 応用微生物 / Clostridium difficile / 腸内フローラ / バイオテクノロジー / 応用微生物学 / 自己誘導因子 / ペプチド / クロストリジア綱細菌 / 酪酸菌 / クロストリジウム / 自己誘導ペプチド / Clostridiales / クオラムクエンチング / gene regulation / virulence / cell-cell signaling / DNA microarray / Clostridium perfringens / 毒素 / 病原細菌 / 眼内炎 / ゼラチナーゼ / デプシペプチド / 阻害剤スクリーニング / グラム陽性日和見感染菌 / クォルモン / 阻害剤開発 / ペプチドデザイン / 抗感染症剤 / 日和見感染 / 遺伝子発現調 / 調節RNA / 芽胞 / ウェルシュ菌食中毒 / 転写調節RNA / 芽胞(胞子) / 食中毒 / ガス壊疽 / 調節RNA分子 / ストレプトリジンO / エンドサイトーシス / 細胞内寄生性細菌 / 細胞壁 / オートインデューサー / 二成分制御系 / 遺伝子発現解析 / オートファジー / マイクロアレイ / A群レンサ球菌 / トランスクリプトーム / ゲノム解析 / 細菌感染症 Less

ウェルシュ菌の細胞間シグナル伝達による芽胞形成調節と病原性発現機構の解明Principal Investigator
- Principal Investigator
  
  大谷郁
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokai University
Elucidation of lethal intravascular hemolysis mechanism in Clostridium perfringens sepsis
- Principal Investigator
  
  SUZAKI Ai
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nihon University
Analysis of regulatory mechanism of sporulation and its signal in Clostridium perfringensPrincipal Investigator
- Principal Investigator
  
  OHTANI Kaori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokai University
  Kanazawa University
Study on quorum sensing in gut microbial community for health promotion and disease prevention
- Principal Investigator
  
  Nakayama Jiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyushu University
Development of antipathogenic agents targeting quorum sensing of Gram-positive bacteria
- Principal Investigator
  
  NAKAYAMA Jiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyushu University
Comprehensive analysis of pathogenesis targeted sporulation of C. perfringensPrincipal Investigator
- Principal Investigator
  
  OHTANI Kaori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Identification and analysis of regulatory sRNAs involved inthe pathogenicity of gas-gangrene related bacteria
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Analysis in pathogenesis of bacterial lethal soft-tissue infection and application to prevention and therapy.
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ウェルシュ菌における細胞間情報伝達による毒素産生調節機構の解析Principal Investigator
- Principal Investigator
  
  大谷郁
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University
Research on the Regulation of Virulence by Cell-Cell Signaling in Pathogenic Bacteria
- Principal Investigator
  
  SHIMIZU Tohru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kanazawa University

[Journal Article] Pathogenic characterization of Clostridium perfringens strains isolated from patients with sepsis associated with massive intravascular hemolysis2021
- Author(s)
  Ai Suzaki, Kaori Ohtani, Shihoko Komine-Aizawa, Asami Matsumoto, Shigeru Kamiya, Satoshi Hayakawa
- Journal Title
  
  frontiers in Microbiology
  
  Volume: 12
- DOI
  10.3389/fmicb.2021.713509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10034
[Journal Article] Metabolic dependent and independent pH-drop shuts down VirSR quorum sensing in Clostridium perfringens.2018
- Author(s)
  Adachi K, Ohtani K, Kawano M, Singh RP, Yousuf B, Sonomoto K, Shimizu T, Nakayama J.
- Journal Title
  
  J Biosci Bioeng
  
  Volume: 17 Issue: 5 Pages: 30903-30909
- DOI
  10.1016/j.jbiosc.2017.12.019
- NAID
  40021552589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08460, KAKENHI-PROJECT-15H04480, KAKENHI-PROJECT-16F16101
[Journal Article] Clostridium perfringens α-Toxin Impairs Innate Immunity via Inhibition of Neutrophil Differentiation.2016
- Author(s)
  Takehara M, Takagishi T, Seike S, Ohtani K, Kobayashi K, Miyamoto K, Shimizu T, Nagahama M
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 28192-28192
- DOI
  10.1038/srep28192
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19099, KAKENHI-PROJECT-15K08460, KAKENHI-PROJECT-16K08794
[Journal Article] Gene regulation by VirS/VirR system in Clostridium perfringens.2016
- Author(s)
  Ohtani K.
- Journal Title
  
  Anaerobe
  
  Volume: 41 Pages: 5-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08460
[Journal Article] Rationale design of quorum-quenching peptides that target the VirSR system of Clostridium perfringens2015
- Author(s)
  Singh RP, Okubo K, Ohtani K, Adachi K, Sonomoto K, Nakayama
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 362 Issue: 22 Pages: 1-7
- DOI
  10.1093/femsle/fnv188
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04480, KAKENHI-PROJECT-13F03389
[Journal Article] Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria2015
- Author(s)
  Desouky SE, Shojima A, Singh RP, Matsufuji T, Igarashi Y, Suzuki T, Yamagaki T, Okubo K, Ohtani K, Sonomoto K, Nakayama J
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 362 Issue: 14 Pages: 1-9
- DOI
  10.1093/femsle/fnv109
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04480, KAKENHI-PROJECT-13F03389
[Journal Article] Regulation of toxin gene expression in Clostridium perfringens2014
- Author(s)
  Ohtani K., T. Shimizu
- Journal Title
  
  Res. in Microbiol.
  
  Volume: 14 Issue: 4 Pages: 190-199
- DOI
  10.1016/j.resmic.2014.09.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590520, KAKENHI-PROJECT-15K08460
[Journal Article] Identification of a two-component signal transduction system that regulates maltose genes in Clostridium perfringens.2014
- Author(s)
  Hiscox T. J., K. Ohtani, T. Shimizu, JK. Cheung, JI Rood
- Journal Title
  
  Anaerobe
  
  Volume: 30 Pages: 199-204
- DOI
  10.1016/j.anaerobe.2014.08.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590520
[Journal Article] Unique regulatory mechanism of sporulation and enterotoxin production in Clostridium perfringens2013
- Author(s)
  Ohtani, K.
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Unique regulatory mechanism of sporulation and enterotoxin production in Clostridium perfringens2013
- Author(s)
  Kaori Ohtani, Hideki Hirakawa, Daniel Paredes-Sabja, Kosuke Tashiro, Satoru Kuhara, Mahfuzur R. Sarker, and Tohru Shimizu
- Journal Title
  
  Journal of Bacteriology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590520
[Journal Article] Unique regulatory mechanism of sporulation and enterotoxin production in C. perfringens2013
- Author(s)
  Kaori Ohtani, Hideki Hirakawa, Daniel Paredes-Sabja, Kosuke Tashiro, Satoru Kuhara, Mahfuzur R. Sarker, and Tohru Shimizu
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 195 Pages: 2931-2931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590520
[Journal Article] Complex transcriptional regulation of citrate metabolism in Clostridium perfringens2012
- Author(s)
  Yuan, Y., Ohtani, K., Yoshizawa, S., Shimizu, T
- Journal Title
  
  Anaerobe
  
  Volume: 18 Issue: 1 Pages: 48-54
- DOI
  10.1016/j.anaerobe.2011.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Identification of a two-component VirR/VirS regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, K., et al.
- Journal Title
  
  Anaerobe (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Identification of a two-component VirR/VirS regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, et.al.
- Journal Title
  
  Anaerobe
  
  Volume: 16 Pages: 258-264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Genetic and biochemical analysis of a class C nonspecific acid phosphatase (NSAP) of Clostridium perfringens2010
- Author(s)
  Wang, R., Ohtani, K., Wang, Y., Yuan, Y., Hassan, S., Shimizu, T.
- Journal Title
  
  Microbiol 156
  
  Pages: 167-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Identification of a two-component VirR/Vir S regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, K., Hirakawa, H., Tashiro, K., Yoshizawa, S., Kuhara, S., Shimizu, T
- Journal Title
  
  Anaerobe
  
  Volume: 16 Issue: 3 Pages: 258-264
- DOI
  10.1016/j.anaerobe.2009.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Global regulation of gene expression in response to cysteine availability in Clostridium perfringens2010
- Author(s)
  Andre, G., Haudecoeur, E., Monot, M., Ohtani, K., Shimizu, T.,(他)
- Journal Title
  
  BMC Microbiol
  
  Volume: 10 Issue: 1 Pages: 234-234
- DOI
  10.1186/1471-2180-10-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Journal Article] Identification of a two-component VirR/VirS regulon in Clostridium perfringens2010
- Author(s)
  Ohtani, K., Hirakawa, H., Tashiro, K., Yoshizawa, S., Kuhara, S., Shimizu, T.
- Journal Title
  
  Anaerobe (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Contact with enterocyte-like Caco-2 cells induces rapid upregulation of toxin production by Clostridium perfringens type C isolates2009
- Author(s)
  Vidal, J.E., Ohtani, K., Shimizu, T., McClane, B.A.
- Journal Title
  
  Cell. Microbiol. 11
  
  Pages: 1306-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Virulence gene regulation by the agr system in Clostridium perfringens2009
- Author(s)
  Ohtani, K., Yuan, Y., Hassan, S., Wang, R., Wang, Y., Shimizu, T.
- Journal Title
  
  J. Bacteriol. 191
  
  Pages: 3919-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Virulence gene regulation by the agr system in Clostridium perfringens2009
- Author(s)
  Ohtani, K, et al.
- Journal Title
  
  Journal of Bacteriology 191
  
  Pages: 3919-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Virulence gene regulation by the agr system in Clostridium perfringens2009
- Author(s)
  K. Ohtani, et.al.
- Journal Title
  
  J. Bacteriol (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens2008
- Author(s)
  Mendez, M., Huang, I.H., Ohtani, K., Grau, R., Shimizu, T., Sarker, M.R.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Characterization of Genes Regulated Directly by the VirR/VirS System in Clostridium perfringens2008
- Author(s)
  Okumura, K., Ohtani, K., Hayashi, H., Shimizu, T.
- Journal Title
  
  J. Bacteriol. 190(23)
  
  Pages: 7719-7727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Carbon catabolite repression of type IV pilus-dependent gliding motility in the anaerobic pathogen Clostridium perfringens2008
- Author(s)
  Mendez M., Huang IH., Ohtani K., Grau R., Shimizu T. and Sarker, MR.
- Journal Title
  
  J. Bacteriol. 190
  
  Pages: 48-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., and Misawa, N.
- Journal Title
  
  J. Bacteriol. 189
  
  Pages: 1633-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] Detection of a group II intron without an open reading frame in the alpha-toxin gene of Clostridium perfringens isolated from a Broiler chicken2007
- Author(s)
  Menglin Ma, Kaori Ohtani, Tohru Shimizu, Naoaki Misawa
- Journal Title
  
  Journal of Bacteriology 189, No5
  
  Pages: 1633-1640
- Data Source
  KAKENHI-PROJECT-17790284
[Journal Article] Detection of a group II intron without open reading frame in the alpha toxin gene of Clostridium perfringens isolated from a broiler chicken2007
- Author(s)
  Ma, M., Ohtani, K., Shimizu, T., Misawa, N.
- Journal Title
  
  J.Bacteriol. 60
  
  Pages: 1633-1640
- Data Source
  KAKENHI-PROJECT-17019021
[Journal Article] ウェルシュ菌のシグナル伝達機構2004
- Author(s)
  清水徹, 大谷郁, 中村信一
- Journal Title
  
  臨床と微生物 31
  
  Pages: 229-237
- NAID
  80016700496
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] Organization and transcriptional regulation of myo-Inositol operon in Closiridium perfringens2004
- Author(s)
  H.I.Kawsar, K.Ohtani, K.Okurnura, H.Hayashi, T.Shimizu
- Journal Title
  
  FEMS Microbiol.Lett. 235
  
  Pages: 289-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390140
[Journal Article] Unique regulatory mechanism of sporulation and enterotoxin production in Clostridium perfringens
- Author(s)
  Ohtani, K., Hirakawa, H., Paredes-Sabja, D., Tashiro, K., Kuhara, S., Sarker, M., Shimizu, T
- Journal Title
  
  J. Bacteriol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390081
[Patent] クロストリジウム属の菌の毒素産生抑制活性を有するペプチド2015
- Inventor(s)
  清水徹、大谷郁、中山二郎、高橋志達、岡健太郎ら
- Industrial Property Rights Holder
  高橋志達、岡健太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-02-04
- Overseas
- Data Source
  KAKENHI-PROJECT-24380050
[Patent] クロストリジウム属の菌の毒素産生抑制活性を有するペプチド2014
- Inventor(s)
  清水徹、大谷郁、中山二郎、高橋志達、岡健太郎ら
- Industrial Property Rights Holder
  高橋志達、岡健太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] VirY, a small regulatory RNA that regulates toxin production in Clostridium perfringens2019
- Author(s)
  Kaori Ohtani, Jackie Cheung, Hideki Hirakawa, Satoru Kuhara, Julian Rood
- Organizer
  BacPath15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0176
[Presentation] Clostridium perfringens の内在性クオラムクエンチング―代謝同調的pH低下によるクオラムセンシング機構の抑制―2017
- Author(s)
  安達桂香，神川美樹，Ravindra Pal Singh，大谷郁，園元謙二，中山二郎
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] Clostridiales目細菌ゲノムにコードされる agr 様クオラムセンシング系自己誘導ペプチドのLC-MS/MS検出系の確立2017
- Author(s)
  中山二郎，神川美樹，安達桂香，大久保謙一，大谷郁，岡健太郎，園元謙二
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] 細菌間コミュニケーションの視点で考える感染症とその治療2017
- Author(s)
  大谷郁
- Organizer
  第９回　J感染制御ネットワークフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-15K08460
[Presentation] Clostridium perfringensの代謝同調的な内在性クオラムクエンチング機構の実態解明2017
- Author(s)
  安達桂香、Ravindra Pal Singh、大谷郁、園元謙二、中山二郎
- Organizer
  環境微生物系学会合同大会
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] ウェルシュ菌の異種菌間細胞間情報伝達による毒素産生調節機構の解析2016
- Author(s)
  大谷　郁、岡　健太郎、高橋　志達
- Organizer
  第９０日本感染症学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-04-15
- Data Source
  KAKENHI-PROJECT-15K08460
[Presentation] Clostridium perfringens の毒素発現を制御する内在性クオラムクエンチングの実態解明2016
- Author(s)
  安達桂香, Ravindra Pal Singh, 大谷郁, 園元謙二, 中山二郎
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] Toxin gene repression of Clostridium perfringens by signal substance produced by Clostridium butyricum2016
- Author(s)
  Ohtani, K, K. Oka, M. Takahashi, J. Nakayama, T. Shimizu
- Organizer
  ASM Microbe 2016
- Place of Presentation
  ボストン
- Year and Date
  2016-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08460
[Presentation] ウェルシュ菌における毒素産生ならびに芽胞形成調節機構の解析2016
- Author(s)
  大谷郁、岡健太郎、田代康介、久原哲、高橋志達、清水徹
- Organizer
  日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15K08460
[Presentation] 異種菌間細胞間情報伝達によるウェルシュ菌病原性関連遺伝子発現調節機構の解析2016
- Author(s)
  大谷　郁、岡　健太郎、高橋　志達
- Organizer
  第１９回日本臨床腸内微生物学会
- Place of Presentation
  杏林大学
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-15K08460
[Presentation] Clostridium perfringensの毒素生産を制御するクオラムクエンチング機構の解明2016
- Author(s)
  安達桂香、大谷郁、河野道生、ラビンドラパルシン、園元謙二、中山二郎
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] Clostridium 属細菌のagr 様クオラムセンシング系における自己誘導ペプチドの検出2016
- Author(s)
  神川美樹，安達桂香，大久保謙一，大谷郁，岡健太郎，高橋志達，園元謙二，中山二郎
- Organizer
  日本農芸化学会2016 年度西日本支部大会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] Clostridium perfringensの毒素産生を制御するクオラムクエンチングに関する研究2015
- Author(s)
  安達桂香、Ravindra Pal Singh、大谷郁、河野通生、園元謙二、中山二郎
- Organizer
  第22回日本生物工学会九州支部宮崎大会
- Place of Presentation
  宮崎大学農学部講義棟（木花キャンパス：宮崎市学園木花台西1丁目1番地）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] Clostridium butyricum MIYAIRI 588が産生するオートインデューサー様ペプチドの同定2015
- Author(s)
  神川美樹、庄島あかね、大久保謙一、松藤貴久、Ravindra Pal Singh、大谷郁、岡健太郎、高橋志達、園元謙二、中山二郎
- Organizer
  第52回化学関連支部合同九州大会
- Place of Presentation
  ◾北九州国際会議場（北九州市小倉北区浅野3-9-30）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15H04480
[Presentation] ウェルシュ菌における内在性クオラムクエンチング誘導物質の精製2014
- Author(s)
  河野通生、大谷郁、Ravindra Pal Singh、石橋直樹、園元謙二、清水徹、中山二郎
- Organizer
  第21回生物工学会九州支部熊本大会
- Place of Presentation
  熊本大学工学部
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] Gene regulation by inter- and intra- cellular signaling in Clostridium perfringens2014
- Author(s)
  大谷郁、中山二郎、清水徹
- Organizer
  日本細菌学会総会
- Place of Presentation
  東京　船堀タワーホール
- Data Source
  KAKENHI-PROJECT-24590520
[Presentation] 放線菌の生産する環状デプシペプチドによるクオラムセンシング阻害作用機構の解明2014
- Author(s)
  庄島あかね、松藤貴久、Said E. Desouky、大久保謙一、Ravindra Pal Singh、清水徹、大谷郁、五十嵐康弘、園元謙二、中山二郎
- Organizer
  第21回生物工学会九州支部熊本大会
- Place of Presentation
  熊本大学工学部
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] ウェルシュ菌における芽胞形成およびエンテロトキシン産生調節機構の解析2013
- Author(s)
  大谷　郁
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉県千葉市幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] Novel regulatory mechanism for spore formation and enterotoxin production in Clostridium perfringens2013
- Author(s)
  大谷郁, Huyen Hoang, 清水徹
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ国際会議場(千葉県)
- Year and Date
  2013-03-18
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] Novel regulatory mechanism for spore formation and enterotoxin production in Clostridium perfringens2013
- Author(s)
  Kaori Ohtani, Huyen Hoang, Tohru Shimizu
- Organizer
  第８６回　日本細菌学会総会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-24590520
[Presentation] Analysis of newly identified toxin gene regulator in Clostridium2013
- Author(s)
  Kaori Ohtani, Hiroyasu Tsutsuki and Tohru Shimizu
- Organizer
  8th international conference on the Molecular Biology and Pathogenesis of the Clostridia
- Place of Presentation
  Palm Cove, Australia
- Data Source
  KAKENHI-PROJECT-24590520
[Presentation] Nove; regulatory mechanism for sopre formation and enterotoxin production in Clostridium perfringens2011
- Author(s)
  Ohtani, K., Hirakawa, H., Paredes-Sabja, D., Tashiro, K., Kuhara, S., Sarker, M., Shimizu, T
- Organizer
  7th International Conference on the Molecular Biology and Pathogenesis o the Clostridia
- Place of Presentation
  Iowa State Center (Ames, Iowa, USA)
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] Novel regulatory mechanism for spore formation and enterotoxin production in Clostridium perfringens2011
- Author(s)
  Ohtani, K, et al.
- Organizer
  7th International Conference of the Molecular Biology and Pathogenesis of the Clostridia
- Place of Presentation
  アメリカ・アイオワ大学(招待講演)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-22390081
[Presentation] ウェルシュ菌における細胞間情報伝達による毒素産生調節機構の解析2009
- Author(s)
  大谷郁
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-14
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Effect of bacterial and host factors on gene expression in Clostridium perfringens2007
- Author(s)
  Ohtani, K., Isu, A., Ohkubo, J., Shimizu, T.
- Organizer
  107th General Meeting of American Society for Microbiology
- Place of Presentation
  トロント(カナダ)
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Biological signaling to gene expression in Clostridium perfringens2006
- Author(s)
  Ohtani, K
- Organizer
  The 5th Clostpath 2006
- Place of Presentation
  Hugh Stewart Hall, Nottingham Univ., U.K.
- Year and Date
  2006-06-24
- Data Source
  KAKENHI-PROJECT-17019021
[Presentation] Identification of autoinducing peptide of Clostridium perfringens and development of its inhibitors
- Author(s)
  Ravindra Pal Singh, Kaori Ohtani, Ryoji Yokohata, Kenji Sonomoto, Toru Shimizu, Jiro Nakayama
- Organizer
  5th ASM conference on cell-cell communicaion in bacteria
- Place of Presentation
  San Antonio
- Year and Date
  2014-10-18 – 2014-10-21
- Data Source
  KAKENHI-PROJECT-24380050
[Presentation] Gene regulation of Clostridium perfringens toxins
- Author(s)
  Kaori Ohtani, Tohru Shimizu
- Organizer
  Clostpath 2015
- Place of Presentation
  ドイツ、フライブルグ
- Year and Date
  2015-09-07 – 2015-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-24590520

1. SHIMIZU Tohru (80235655)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. NAKAYAMA Jiro (40217930)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. NAKAGAWA Ichiro (70294113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAGATA Koji (30280788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IGARASHI Yasuhiro (20285159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SUZUKI Takashi (70398048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OZAKI Eijirou (40334750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZAKI Ai (90251454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 早川智 (30238084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 相澤志保子 (30513858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TRINH DUYQUANG (90647190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 神谷茂 (10177587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. TAKAHASHI Motomichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. OKA Kentaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. NAGAHAMA Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. KOBAYASHI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 竹原正也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

otani kaori 大谷 郁

OHTANI Kaori 大谷 郁

Research Projects

Research Products

Co-Researchers

ウェルシュ菌の細胞間シグナル伝達による芽胞形成調節と病原性発現機構の解明Principal Investigator

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Elucidation of lethal intravascular hemolysis mechanism in Clostridium perfringens sepsis

Principal Investigator

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Analysis of regulatory mechanism of sporulation and its signal in Clostridium perfringensPrincipal Investigator

Principal Investigator

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Study on quorum sensing in gut microbial community for health promotion and disease prevention

Principal Investigator

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Development of antipathogenic agents targeting quorum sensing of Gram-positive bacteria

Principal Investigator

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Comprehensive analysis of pathogenesis targeted sporulation of C. perfringensPrincipal Investigator

Principal Investigator

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Identification and analysis of regulatory sRNAs involved inthe pathogenicity of gas-gangrene related bacteria

Principal Investigator

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Analysis in pathogenesis of bacterial lethal soft-tissue infection and application to prevention and therapy.

Principal Investigator

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Review Section

Research Institution

ウェルシュ菌における細胞間情報伝達による毒素産生調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Research on the Regulation of Virulence by Cell-Cell Signaling in Pathogenic Bacteria

Principal Investigator

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[Journal Article] Pathogenic characterization of Clostridium perfringens strains isolated from patients with sepsis associated with massive intravascular hemolysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic dependent and independent pH-drop shuts down VirSR quorum sensing in Clostridium perfringens.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Clostridium perfringens α-Toxin Impairs Innate Immunity via Inhibition of Neutrophil Differentiation.2016

Author(s)

Journal Title

DOI

otani kaori 大谷郁

OHTANI Kaori 大谷郁