Aizawa Shihoko 相澤志保子

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AIZAWA Shihoko 相澤志保子

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Researcher Number	30513858
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 日本大学, 医学部, 教授 2014 – 2024: 日本大学, 医学部, 准教授 2012 – 2014: 日本大学, 医学部, 助教 2008 – 2011: 日本大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Obstetrics and gynecology / Infectious disease medicine Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 54030:Infectious disease medicine-related / Infectious disease medicine / Digestive surgery
Keywords	Principal Investigator ワクチン / 非結核性抗酸菌 / BCG / 組換えBCG / 細胞性免疫 / 非結核性抗酸菌症 / 抗酸菌 / 感染免疫 / 感染防御 / 抗原提示 … More / CD8エピトープ / ヘルパーT細胞 / 細胞傷害性T細胞 / 結核 / マウスモデル / 制御性B細胞 / 自然リンパ球 / 母児免疫寛容 / NK細胞 / 制御性T細胞 / 生殖免疫 / 寄生虫 / 流産 / 不育症 / 徴生物 / インフルエンザウイルス / 胎盤 / 微生物 … More Except Principal Investigator 垂直感染 / 胎盤関門 / 絨毛細胞 / 風疹ウイルス / 母子感染 / サイトカイン / 歯周病 / HIV / 小胞体ストレス / TGF-β1 / ジカウイルス / 新型コロナウイルス / TGF-β / ワクチン / 経胎盤感染 / 感染症 / NK細胞 / インフルエンザ / 異常妊娠 / 妊娠維持 / 女性生殖器 / 常在微生物叢 / ヒト胎盤栄養膜細胞 / 酸化ストレス / グルコースストレス / 副反応 / 新型コロナウイルス感染症 / 妊婦 / COVID-19 / 栄養膜細胞 / 感受性 / ヒト不死化絨毛細胞HTR-8 / SVneo細胞 / A549 / trophoblast / 低グルコース / ヒト不死化絨毛細胞 / 上皮間葉転換 / トランスフォーミング増殖因子ベータ1 / 低グルコースストレス / 感染性 / 先天性風疹症候群 / 妊娠 / TORCH症候群 / 胎盤マイクロバイオーム / 口腔細菌 / ウイルス垂直感染 / 子宮内フローラ / マイクロバイオーム / 子宮内細菌叢 / 慢性炎症 / 血管内皮 / 絨毛羊膜炎 / ジカ熱 / 感染免疫 / CTL / 組換えBCG / 抗酸菌 / 細胞性免疫 / BCG / 結核 / 急性呼吸窮迫症候群 / θトキシン / 溶血毒 / 血管内溶血 / 敗血症 / ウェルシュ菌 / 細菌性腟症 / 婦人科学 / T 細胞 / 免疫応答 / 細菌 / 共培養 / 菌体成分 / 不活化細菌菌体 / HIV 複製 / 再上皮化 / Lactobacillus crispatus / HMGB1 / T細胞 / HIV複製 / 抗微生物ペプチド / 腟上皮細胞 / マクロライド系抗菌薬 / 妊娠高血圧症候群 / マイクロビオーム / VPｘ / 上皮間葉移行 / 風疹 / マウスモデル / 衛生仮説 / 免疫調節 / 寄生虫 / Th17 / 寄生虫抗原 / 免疫機序 / 習慣流産 / 脂肪代謝 / 脂質代謝 / 免疫学 / オステオポンテイン / 炎症性腸疾患 / クローン病 / 潰瘍性大腸炎 / アロマテラピー / IDO / 転写因子 / 大顆粒リンパ球 / NKT細胞 / CD56 / アポトーシス / TLR / 脱落膜リンパ球 / IL-16 / リザーバー Less

Total microbiota of human female reproductive tract
- Principal Investigator
  
  早川智
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nihon University
組換えBCGとDNAワクチンのプライムブースト接種法による新たなワクチン開発の試みPrincipal Investigator
- Principal Investigator
  
  相澤志保子
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nihon University
Study on mechanisms of transplacental infection of Zika virus, SARS-CoV-2, rubella virus, and possible factors affecting these virus infections in pregnancy
- Principal Investigator
  
  TRINH DUYQUANG
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nihon University
Placental barrier of SARS-CoV-2
- Principal Investigator
  
  早川智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nihon University
Study on mechanisms of rubella virus infection to the fetus, possible alternative cellular receptors and factors affecting the virus infection
- Principal Investigator
  
  TRINH DuyQuang
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nihon University
Study on cellular immunity against Mycobacterium and development of new vaccinePrincipal Investigator
- Principal Investigator
  
  AIZAWA Shihoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Nihon University
Elucidation of lethal intravascular hemolysis mechanism in Clostridium perfringens sepsis
- Principal Investigator
  
  SUZAKI Ai
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nihon University
Development of novel recombinant BCG vaccine and its immunological analysis
- Principal Investigator
  
  HONDA Mitsuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nihon University
Molecular backgrounds of transplacental Zika fever infection.
- Principal Investigator
  
  HAYAKAWA Satoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
Development of novel recombinant BCG vaccine and its immunological analysisPrincipal Investigator
- Principal Investigator
  
  AIZAWA Shihoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nihon University
Influence of the mucosal immune response to the vaginal bacterial flora on HIV infection
- Principal Investigator
  
  TRINH DuyQuang
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
Analysis of placental barrier functions for intra uterine viral infections
- Principal Investigator
  
  HAYAKAWA Satoshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
Immunological analysis of immune-mediated pregnancy loss.Principal Investigator
- Principal Investigator
  
  AIZAWA Shihoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
Therapeutic potentials of parasitic antigens on a murine recurrent spontaneous abortion
- Principal Investigator
  
  HAYAKAWA Satoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
Placenta as a target of influenza virus infectionPrincipal Investigator
- Principal Investigator
  
  AIZAWA Shihoko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University
T cell function in ulcerative colitis, particularly relationship between osteopontin and ulcerative colitis
- Principal Investigator
  
  MASUDA Hideki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nihon University
Role of local decidual large granular luphocytes and local immune responses on materno-fetal HIV transmission
- Principal Investigator
  
  HAYAKAWA Satoshi
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nihon University

[Book] 妊娠と感染症, HIV (鈴木光明吉村泰典編産婦人科専門医に聞く最新の臨床)2007
- Author(s)
  早川智, 相澤志保子
- Total Pages
  41
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17390454
[Book] 妊娠と感染症 HIV 産婦人科専門医に聞く最新の臨床(鈴木光明吉村泰典編)2007
- Author(s)
  早川智・相澤(小峯)志保子
- Total Pages
  442
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] Roles of TGF-β1 in Viral Infection during Pregnancy: Research Update and Perspectives2023
- Author(s)
  Trinh Quang Duy、Pham Ngan Thi Kim、Takada Kazuhide、Ushijima Hiroshi、Komine-Aizawa Shihoko、Hayakawa Satoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 7 Pages: 6489-6489
- DOI
  10.3390/ijms24076489
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08829
[Journal Article] Outbreak of human astroviruses 1 and Melbourne 2 in acute gastroenteritis pediatric patients in Japan during the COVID-19 pandemic, 20212023
- Author(s)
  Ushijima Hiroshi、Nishimura Shuichi、Shimizu-Onda Yuko、Thi Kim Pham Ngan、Trinh Quang Duy、Okitsu Shoko、Takano Chika、Kumthip Kattareeya、Hoque Sheikh Ariful、Komine-Aizawa Shihoko、Maneekarn Niwat、Hayakawa Satoshi、Khamrin Pattara
- Journal Title
  
  Journal of Infection and Public Health
  
  Volume: 16 Issue: 8 Pages: 1301-1305
- DOI
  10.1016/j.jiph.2023.05.034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07929
[Journal Article] Genetic diversity and declining norovirus prevalence in infants and children during Japan's COVID-19 pandemic: a three-year molecular surveillance2023
- Author(s)
  Pham Ngan Thi Kim、Khamrin Pattara、Shimizu-Onda Yuko、Hoque Sheikh Ariful、Trinh Quang Duy、Komine-Aizawa Shihoko、Okitsu Shoko、Maneekarn Niwat、Hayakawa Satoshi、Yoshimune Kazuaki、Ushijima Hiroshi
- Journal Title
  
  Archives of Virology
  
  Volume: 168 Issue: 9 Pages: 231-231
- DOI
  10.1007/s00705-023-05856-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07929
[Journal Article] Enhancement of Rubella Virus Infection in Immortalized Human First-Trimester Trophoblasts Under Low-Glucose Stress Conditions2022
- Author(s)
  Trinh Quang Duy、Takada Kazuhide、Pham Ngan Thi Kim、Takano Chika、Namiki Takahiro、Ikuta Ryo、Hayashida Shingo、Okitsu Shoko、Ushijima Hiroshi、Komine-Aizawa Shihoko、Hayakawa Satoshi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 13 Pages: 904189-904189
- DOI
  10.3389/fmicb.2022.904189
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08829
[Journal Article] TGF-β1 Promotes Zika Virus Infection in Immortalized Human First-Trimester Trophoblasts via the Smad Pathway2022
- Author(s)
  Trinh QD, Pham NTK, Takada K, Takano C, Komine-Aizawa S, Hayakawa S.
- Journal Title
  
  Cells
  
  Volume: 27 Issue: 19 Pages: 3026-3026
- DOI
  10.3390/cells11193026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04341, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-23K24488
[Journal Article] Emerging norovirus GII.4 Sydney[P31] causing acute gastroenteritis outbreak in children in Japan, during COVID-19, 20212022
- Author(s)
  Pham Ngan Thi Kim、Nishimura Shuichi、Shimizu-Onda Yuko、Trinh Quang Duy、Komine-Aizawa Shihoko、Khamrin Pattara、Okitsu Shoko、Sato Shintaro、Kobayashi Takeshi、Maneekarn Niwat、Hayakawa Satoshi、Ushijima Hiroshi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 28 Issue: 9 Pages: 1347-1351
- DOI
  10.1016/j.jiac.2022.05.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-21K19379
[Journal Article] Low Susceptibility of Rubella Virus in First-Trimester Trophoblast Cell Lines2022
- Author(s)
  Pham Ngan Thi Kim、Trinh Quang Duy、Takada Kazuhide、Komine-Aizawa Shihoko、Hayakawa Satoshi
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 6 Pages: 1169-1169
- DOI
  10.3390/v14061169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08829
[Journal Article] Restriction of SARS-CoV-2 replication in the human placenta.2022
- Author(s)
  Takada K, Shimodai-Yamada S, Suzuki M, Quang Duy Trinh, Takano C, Kawakami K, Asai-Sato M, Komatsu A, Okahashi A, Nagano N, Misawa T, Yamaguchi K, Kawana K, Morioka I, Yamada H, Hayakawa S. Hao H, Komine-Aizawa S
- Journal Title
  
  Placenta.
  
  Volume: 127 Pages: 73-76
- DOI
  10.1016/j.placenta.2022.07.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09642, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-23K24488
[Journal Article] Adverse events after BNT162b2 mRNA COVID-19 vaccination in health care workers and medical students in Japan2022
- Author(s)
  Namiki Takahiro、Komine-Aizawa Shihoko、Takada Kazuhide、Takano Chika、Trinh Quang Duy、Hayakawa Satoshi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 28 Issue: 8 Pages: 1220-1224
- DOI
  10.1016/j.jiac.2022.05.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08829
[Journal Article] Inhibition of Epithelial-Mesenchymal Transition Maintains Stemness in Human Amniotic Epithelial Cells2022
- Author(s)
  Takano Chika、Horie Masafumi、Taiko Isamu、Trinh Quang Duy、Kanemaru Kazunori、Komine-Aizawa Shihoko、Hayakawa Satoshi、Miki Toshio
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 18 Issue: 8 Pages: 3083-3091
- DOI
  10.1007/s12015-022-10420-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19574, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-20K17522, KAKENHI-PROJECT-23K24398
[Journal Article] The association of three doses of the BNT162b2 mRNA vaccine with abnormal bleeding and an irregular menstrual cycle among premenopausal females: A single institute observation study2022
- Author(s)
  Namiki Takahiro、Komine‐Aizawa Shihoko、Takada Kazuhide、Takano Chika、Trinh Quang Duy、Hayakawa Satoshi
- Journal Title
  
  Journal of Obstetrics and Gynaecology Research
  
  Volume: 48 Issue: 11 Pages: 2903-2910
- DOI
  10.1111/jog.15400
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-23K24488
[Journal Article] The Epithelial-to-Mesenchymal Transition-Like Process Induced by TGF-β1 Enhances Rubella Virus Binding and Infection in A549 Cells via the Smad Pathway2021
- Author(s)
  Pham Thi Kim Ngan、Trinh Duy Quang、Takada Kazuhide、Takano Chika、Sasano Mari、Okitsu Shoko、Ushijima Hiroshi、Komine-Aizawa Shihoko、Hayakawa Satoshi
- Journal Title
  
  Microorganisms
  
  Volume: 9 Issue: 3 Pages: 662-662
- DOI
  10.3390/microorganisms9030662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08829, KAKENHI-PROJECT-17H04341
[Journal Article] Genetic diversity of Parechovirus A in infants and children with acute gastroenteritis in Japan during 2016-20182021
- Author(s)
  Pham Thi Kim Ngan、Thongprachum Aksara、Shimizu Yuko、Shiota Itoe、Hoque Sheikh Ariful、Khamrin Pattara、Takano Chika、Trinh Duy Quang、Okitsu Shoko、Komine-Aizawa Shihoko、Shimizu Hiroyuki、Maneekarn Niwat、Hayakawa Satoshi、Ushijima Hiroshi
- Journal Title
  
  Infection, Genetics and Evolution
  
  Volume: 90 Pages: 104776-104776
- DOI
  10.1016/j.meegid.2021.104776
- Data Source
  KAKENHI-PROJECT-20K08829
[Journal Article] Recombinant BCG-Prime and DNA-Boost Immunization Confers Mice with Enhanced Protection against Mycobacterium kansasii2021
- Author(s)
  Komine-Aizawa Shihoko、Mizuno Satoru、Matsuo Kazuhiro、Namiki Takahiro、Hayakawa Satoshi、Honda Mitsuo
- Journal Title
  
  Vaccines
  
  Volume: 9 Issue: 11 Pages: 1260-1260
- DOI
  10.3390/vaccines9111260
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08939
[Journal Article] Anti-SARS-CoV-2 vaccination strategy for pregnant women in Japan.2021
- Author(s)
  Hayakawa S, Komine-Aizawa S, Takada K, Kimura T, Yamada H.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 47 Issue: 6 Pages: 14748-14748
- DOI
  10.1111/jog.14748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Pathogenic characterization of Clostridium perfringens strains isolated from patients with sepsis associated with massive intravascular hemolysis2021
- Author(s)
  Ai Suzaki, Kaori Ohtani, Shihoko Komine-Aizawa, Asami Matsumoto, Shigeru Kamiya, Satoshi Hayakawa
- Journal Title
  
  frontiers in Microbiology
  
  Volume: 12
- DOI
  10.3389/fmicb.2021.713509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10034
[Journal Article] Covid-19 pandemic and pregnancy.2020
- Author(s)
  Hayakawa S, Komine-Aizawa S, Mor GG.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 46 Issue: 10 Pages: 1958-1966
- DOI
  10.1111/jog.14384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Cow milk exosomes activate NK cells and γδT cells in human PBMCs in?vitro2020
- Author(s)
  Shihoko Komine-Aizawa、Shun Ito、Shu Aizawa、Takahiro Namiki、Satoshi Hayakawa
- Journal Title
  
  Immunological Medicine
  
  Volume: 43 Issue: 4 Pages: 161-170
- DOI
  10.1080/25785826.2020.1791400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06375, KAKENHI-PROJECT-17H04341
[Journal Article] Placental barrier against COVID-19.2020
- Author(s)
  Komine-Aizawa S, Takada K, Hayakawa S.
- Journal Title
  
  Placenta. Sep 15;99:45-49. doi:
  
  Volume: 99 Pages: 45-49
- DOI
  10.1016/j.placenta.2020.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] MHC-restricted Ag85B-specific CD8+ T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice2019
- Author(s)
  Komine-Aizawa S, Jiang J, Mizuno S, Hayakawa S, Matsuo K, Boyd LF, Margulies DH, Honda M.
- Journal Title
  
  .Eur J Immunol.
  
  Volume: 49 Issue: 9 Pages: 1399-1414
- DOI
  10.1002/eji.201847988
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04341, KAKENHI-PROJECT-17K10035
[Journal Article] Relationship Between the Fecal Microbiota and Depression and Anxiety in Pediatric Patients With Orthostatic Intolerance.2019
- Author(s)
  Ishii W, Komine-Aizawa S, Takano C, Fujita Y, Morioka I, Hayakawa S.
- Journal Title
  
  Prim Care Companion CNS Disord.
  
  Volume: 21 Issue: 2
- DOI
  10.4088/pcc.18m02401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Periodontal diseases and adverse pregnancy outcomes.2019
- Author(s)
  Komine-Aizawa S, Aizawa S, Hayakawa S
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 45 Issue: 1 Pages: 5-12
- DOI
  10.1111/jog.13782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Diversity of human parechovirus in infants and children with acute gastroenteritis in Japan during 2014?20162019
- Author(s)
  Pham Ngan Thi Kim、Thongprachum Aksara、Shimizu Yuko、Trinh Quang Duy、Okitsu Shoko、Komine-Aizawa Shihoko、Shimizu Hiroyuki、Hayakawa Satoshi、Ushijima Hiroshi
- Journal Title
  
  Infection, Genetics and Evolution
  
  Volume: 75 Pages: 104001-104001
- DOI
  10.1016/j.meegid.2019.104001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05360, KAKENHI-PROJECT-17H04341
[Journal Article] Synergistic induction of interferon-γ by interleukin-2, interleukin-12 and poly(I:C) in a human natural killer cell line2018
- Author(s)
  Majima-Horiuchi H, Komine-Aizawa S, Karasaki-Suzuki M, Izumi Y, Aizawa S, Hayakawa S. .
- Journal Title
  
  Immunol Med.
  
  Volume: 41 Issue: 3 Pages: 136-141
- DOI
  10.1080/25785826.2018.1531193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Lactobacillus crispatus accelerates re-epithelialization in vaginal epithelial cell line MS74.2018
- Author(s)
  Takada K, Komine-Aizawa S, Kuramochi T, Ito S, Trinh QD, Pham NTK, Sasano M, Hayakawa S.
- Journal Title
  
  Am J Reprod Immunol.
  
  Volume: 80 Issue: 3
- DOI
  10.1111/aji.13027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04341, KAKENHI-PROJECT-16K11160
[Journal Article] Detection and genetic characterization of enterovirus strains circulating among children with acute gastroenteritis in Japan during 2014?20162018
- Author(s)
  Ngan Thi Kim Pham、Aksara Thongprachum、Quang Duy Trinh、Shoko Okitsu、Shihoko Komine-Aizawa、Hiroyuki Shimizu、Satoshi Hayakawa、Hiroshi Ushijima
- Journal Title
  
  Infection, Genetics and Evolution
  
  Volume: 61 Pages: 16-19
- DOI
  10.1016/j.meegid.2018.03.009
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11160, KAKENHI-PROJECT-16H05200, KAKENHI-PROJECT-16H05360
[Journal Article] Frequent isolation of extended-spectrum beta-lactamase-producing bacteria from fecal samples of individuals with severe motor and intellectual disabilities.2018
- Author(s)
  Takano C, Seki M, Shiihara H, Komine-Aizawa S, Kuroda K, Takahashi S, Ushijima H, Hayakawa S.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 24 Issue: 3 Pages: 182-187
- DOI
  10.1016/j.jiac.2017.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Myelin oligodendrocyte glycoprotein-independent rubella infection of keratinocytes and resistance of first-trimester trophoblast cells to rubella virus in vitro2018
- Author(s)
  Quang Duy Trinh、Ngan Thi Kim Pham、Kazuhide Takada、Shihoko Komine-Aizawa、Satoshi Hayakawa
- Journal Title
  
  Viruses
  
  Volume: 10 Issue: 1 Pages: 23-23
- DOI
  10.3390/v10010023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11160, KAKENHI-PROJECT-17H04341
[Journal Article] Poly I:C induces collective migration of HaCaT keratinocytes via IL-8.2017
- Author(s)
  Takada K, Komine-Aizawa S, Hirohata N, Trinh QD, Nishina A, Kimura H, Hayakawa S.
- Journal Title
  
  BMC Immunol.
  
  Volume: 18 Issue: 1 Pages: 19-19
- DOI
  10.1186/s12865-017-0202-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04341
[Journal Article] Porphyromonas gingivalis Suppresses Trophoblast Invasion by Soluble Factors.2017
- Author(s)
  Hirohata N, Komine-Aizawa S, Tamura M, Ochiai K, Sugitani M, Hayakawa S. .
- Journal Title
  
  J Periodontol
  
  Volume: 88 Issue: 12 Pages: 1366-1373
- DOI
  10.1902/jop.2017.170193
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04341, KAKENHI-PROJECT-15K11456
[Journal Article] Multiplex PCR for the detection of 10 viruses causing encephalitis/encephalopathy and its application to clinical samples collected from Japanese children with suspected viral encephalitis/encephalopathy.2017
- Author(s)
  Pham NT, Ushijima H, Thongprachum A, Trinh QD, Khamrin P, Arakawa C, Ishii W, Okitsu S, Komine-Aizawa S, Hayakawa S
- Journal Title
  
  Clin Lab
  
  Volume: 63 Issue: 01/2017 Pages: 91-100
- DOI
  10.7754/clin.lab.2016.160630
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05360, KAKENHI-PROJECT-16K11160
[Journal Article] High Mobility Group Box 1 protein enhances HIV replication in newly infected primary T cells2016
- Author(s)
  Quang Duy Trinh, Ngan Thi Kim Pham, Kazumasa Fuwa, Kazuhide Takada, Shihoko Komine-Aizawa, Mitsuo Honda, Hiroshi Ushijima, Satoshi Hayakawa
- Journal Title
  
  Clinical Laboratory
  
  Volume: 62 Issue: 12/2016 Pages: 2305-2311
- DOI
  10.7754/clin.lab.2016.150928
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K11160
[Journal Article] Porphyromonas gingivalis lipopolysaccharide inhibits trophoblast invasion in the presence of nicotine.2015
- Author(s)
  Komine-Aizawa S, Hirohata N, Aizawa S, Abiko Y, Hayakawa S.
- Journal Title
  
  Placenta
  
  Volume: 36 Issue: 1 Pages: 27-33
- DOI
  10.1016/j.placenta.2014.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390382
[Journal Article] 女性と三大感染症　HIV/AIDS、結核、マラリア2015
- Author(s)
  相澤志保子，本多三男, トリン・ズイ・クアン , 早川智
- Journal Title
  
  産婦人科の実際
  
  Volume: 64 Pages: 1837-43
- Data Source
  KAKENHI-PROJECT-24390382
[Journal Article] Suppression of osteoblast toll-like receptor 2 signaling by endothelin-1.2014
- Author(s)
  Suzaki A, Komine-Aizawa S, Hayakawa S
- Journal Title
  
  J Orthop Res.
  
  Volume: 33 Issue: 7 Pages: 910-914
- DOI
  10.1002/jor.22627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390382
[Journal Article] The virucidal effect against murine norovirus and feline calicivirus as surrogates for human norovirus by ethanol-based sanitilizers2013
- Author(s)
  Shimizu-Onda Y
- Journal Title
  
  J Infect Chemother
  
  Volume: - Issue: 4 Pages: 779-781
- DOI
  10.1007/s10156-012-0516-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406036, KAKENHI-PROJECT-24390266, KAKENHI-PROJECT-24390382
[Journal Article] Short communication : Drug resistance mutations in the HIV type 1 protease and reverse transcriptase genes in antiretroviral-naive Vietnamese children.2013
- Author(s)
  Trinh QD, Pham NT, Le Nguyen NT, Lam BQ, Le Phan KT, Truong KH, Izumi Y, Komine-Aizawa S, Mizuguchi M, Ushijima H, Hayakawa S.
- Journal Title
  
  AIDS Res Hum Retroviruses.
  
  Volume: 28 Pages: 1305-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390382
[Journal Article] Seroprevalence of chlamydophila pneumoniae in HIV-infected children in Vietnam2013
- Author(s)
  Trinh QD, Pham NT, Le Nguyen NT, Lam BQ, Le Phan KT, Troonq KH, Le TQ, Nguyen HT, Tang TC, Izumi Y, Komine-Aizawa S, Ushijima H, Hayakawa S
- Journal Title
  
  J Infect Chemother
  
  Volume: 19(3) Issue: 3 Pages: 538-541
- DOI
  10.1007/s10156-012-0483-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406036, KAKENHI-PROJECT-24390266, KAKENHI-PROJECT-24390382
[Journal Article] H1N1/09 Influenza A Virus Infection of Immortalized First Trimester Human Trophoblast Cell Lines2012
- Author(s)
  Shihoko Komine-Aizawa, Ai Suzaki, Quang D. Trinh, Yasuyuki Izumi, Toshikatsu Shibata, Kazumichi Kuroda, Satoshi Hayakawa
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 68 Issue: 3 Pages: 226-232
- DOI
  10.1111/j.1600-0897.2012.01172.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791574, KAKENHI-PROJECT-24390382
[Journal Article] CBA/J×DBA/2J流産マウスモデルにおける"当帰芍薬散""柴苓湯"の効果2012
- Author(s)
  相澤(小峯)志保子, 早川智
- Journal Title
  
  産婦人科漢方研究の歩み
  
  Volume: 29
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] 【不育症最前線】感染症と不育症2011
- Author(s)
  相澤志保子, 早川智
- Journal Title
  
  産婦人科の実際
  
  Volume: 60巻10号 Pages: 1497-1501
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] The therapeutic potential of the recombinant antigen from Dirofilaria immitis (rDiAg) for immune-mediated pregnancy loss2011
- Author(s)
  Komine-Aizawa S, Izumi Y, Imai S, Fujita K, Hayakawa S
- Journal Title
  
  J Reprod Immunol
  
  Volume: 92 Pages: 21-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] 【母体感染症Up to Date】総説妊婦における免疫の変化2011
- Author(s)
  早川智, 相澤志保子
- Journal Title
  
  周産期医学
  
  Volume: 41 Pages: 154160-154160
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] The therapeutic potential of the recombinant antigen from Dirofilaria immitis(rDiAg) for immune-mediated pregnancy loss2011
- Author(s)
  Komine-Aizawa S, Izumi Y, Imai S, Fujita K, Hayakawa S
- Journal Title
  
  J Reprod Immunol
  
  Volume: 92(1-2) Pages: 21-6
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] Influence of advanced age on Mycobacterium bovis BCG vaccination in guinea pigs aerogenically infected with Mycobacterium tuberculosis2010
- Author(s)
  Komine-Aizawa S, Yamazaki T, Hattori S, Miyamoto Y, Yamamoto N, Haga S, Sugitani M, Honda M, Hayakawa S, Yamamoto S
- Journal Title
  
  Clin Vaccine Immunol vol.17
  
  Pages: 1500-1506
- Data Source
  KAKENHI-PROJECT-20591595
[Journal Article] Influence of advanced age on Mycobacterium bovis BCG vaccination in guinea pigs aerogenically infected with Mycobacterium tuberculosis2010
- Author(s)
  Komine-Aizawa S, Yamazaki T, Yamazaki T, Hattori S, Miyamoto Y, Yamamoto N, Haga S, Sugitani M, Honda M, Hayakawa S, Yamamoto S
- Journal Title
  
  Clin Vaccine Immunol
  
  Volume: 17(10) Pages: 1500-6
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] Influence of advanced age on Mycobacterium bovis BCG vaccination in guinea pigs aerogenically infected with Mycobacterium tuberculosis.2010
- Author(s)
  Komine-Aizawa S, Yamazaki T, Yamazaki T, Hattori S, Miyamoto Y, Yamamoto N, Haga S, Sugitani M, Honda M, Hayakawa S, Yamamoto S
- Journal Title
  
  Clin Vaccine Immunol.
  
  Volume: 17 Pages: 1500-1506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] 【妊娠免疫Update子宮内膜局所免疫と妊娠】Toll-like receptorの胎盤における機能2010
- Author(s)
  相澤志保子, 早川智
- Journal Title
  
  医学のあゆみ
  
  Volume: 233 Pages: 147-150
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] H3N2 influenza A virus replicates in immortalized human first trimester trophoblast cell lines and induces their rapid apoptosis2009
- Author(s)
  Trinh QD, Izumi Y, Komine-Aizawa S, Shibata T,Shimotai Y, Kuroda K, Mizuguchi M, Ushijima H, Mor G, Hayakawa S
- Journal Title
  
  Am J Reprod Immunol 62(3)
  
  Pages: 139-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] H3N2 influenza A virus replicates in immortalized human first trimester trophoblast cell lines and induces their rapid apoptosis2009
- Author(s)
  Trinh QD, Izumi Y, Komine-Aizawa S, Shibata T, Shimotai Y, Kuroda K, Mizuguchi M, Ushijima H, Mor G, Hayakawa S.
- Journal Title
  
  American Journal of Reproductive Immunology 62
  
  Pages: 139-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592114
[Journal Article] H3N2 influenza A virus replicates in immortalized human first trimester trophoblast cell lines and induces their rapid apoptosis.2009
- Author(s)
  Trinh QD, Izumi Y, Komine-Aizawa S, Shibata T, Shimotai Y, Kuroda K, Mizuguchi M, Ushijima H, Mor G, Hayakawa S.
- Journal Title
  
  Am J Reprod Immunol 62(3)
  
  Pages: 139-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791574
[Journal Article] H3N2 influenza A virus replicates in immortalized human first trimester trophoblast cell lines and induces their rapid apoptosis2009
- Author(s)
  Trinh QD, Izumi Y, Komine-Aizawa S, Shibata T, Shimotai Y, Kuroda K, Mizuguchi M, Ushijima H, Mor G, Hayakawa S
- Journal Title
  
  Am J Reprod Immunol 62(3)
  
  Pages: 139-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791574
[Journal Article] Stimuli through Toll-like receptor(TLR)3 and 9 affect human chorionic gonadotropin(hCG)production in a choriocarcinoma cell line2008
- Author(s)
  Komine-Aizawa S, Majima H, Yoshida-Noro C Hayakawa S
- Journal Title
  
  J. Obstet. Gynecol. Res (in press)
- NAID
  10021250641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 産婦人科感染症診療マニュアル胎児・新生児の免疫機構2008
- Author(s)
  真島洋子, 早川智, 相澤志保子, 泉泰之, TrinhDuy Quang, 太田邦明, 須崎愛
- Journal Title
  
  産科と婦人科 75(11)
  
  Pages: 1361-68
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] Stimuli through Toll-like receptor (TLR) 3 and 9 affect human chorionic gonadotropin (hCG) production in a choriocarcinoma cell line2008
- Author(s)
  Komine-Aizawa S, Majima H, Yoshida- Noro C, Hayakawa S
- Journal Title
  
  J Obstet Gynaecol Res 34(2)
  
  Pages: 144-51
- NAID
  10021250641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 【妊婦感染症を考える】女性生殖器・脱落膜の免疫と母子感染2008
- Author(s)
  早川智, 真島洋子, 泉泰之, Tirnh Duan Quang, NbandithViengvansay, 相澤志保子
- Journal Title
  
  産婦人科の実際 57
  
  Pages: 773-780
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 女性生殖器・脱落膜の免疫と母子感染2008
- Author(s)
  早川智, 真島洋子, 泉泰之, Tireh Duy Quang, Nbandith Viengvansay, 相澤志保子
- Journal Title
  
  産婦人科の実際 57巻5号
  
  Pages: 773-780
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 当帰芍薬散は内在性レトロウイルスenv遺伝子産物syncytinを介して絨毛癌細胞株BeWoの分化とhCG産生を促進する2008
- Author(s)
  相澤志保子, 真島洋子, 早川智
- Journal Title
  
  産婦人科漢方研究のあゆみ 25
  
  Pages: 95-98
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] Rembrandt's Maria Bockenolle has a butterfly rash and digital deformities : Overlapping syndrome of rheumatoid arthritis and systemic lupus erythematosus.2007
- Author(s)
  Hayakawa S, Komine-Aizawa S, Osaka S, Iida T, Hayakawa J, Nishinarita S, Nemoto N
- Journal Title
  
  Med Hypotheses. 68
  
  Pages: 906-909
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 生殖器の感染症女性生殖器における免疫機構2007
- Author(s)
  早川智, 真島洋子, 相澤志保子
- Journal Title
  
  実験医学 25
  
  Pages: 3254-3261
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 結核菌感染防御システム CD1 による脂質抗原提示2007
- Author(s)
  相澤志保子, 早川智, 本多三男
- Journal Title
  
  日大医学雑誌 66
  
  Pages: 375-376
- NAID
  10019856146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] ベルガモットはHIV複製を抑制する2007
- Author(s)
  相澤志保子, 長縄聰, 真島洋子, 北村勝彦, 本多三男, 早川智
- Journal Title
  
  産婦人科漢方研究のあゆみ 24
  
  Pages: 123-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 鄭瑞巣アロマテラピーに用いられる芳香物質のHIV感染に及ぼす影響MAGIC-5細胞を用いた in vitro での検討2006
- Author(s)
  長縄聰, 早川智, 相澤志保子, 清水一史, 北村勝彦, 本多三男, 陳旺全
- Journal Title
  
  アロマテラピー学雑誌 (1346-3748) 6巻1号
  
  Pages: 19-25
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] HIV垂直感染と胎盤関門2006
- Author(s)
  相澤 (小峯) 志保子, 早川智, 長縄聰, 永石 (石井) 真木, 本多三男, 砂川恵伸, 根本則道
- Journal Title
  
  炎症と免疫 15巻1号
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] HIV垂直感染と胎盤関門2006
- Author(s)
  相澤志保子, 早川智, 長縄聰, 永石真木[石井], 本多三男, 砂川恵伸, 根本則道
- Journal Title
  
  炎症と免疫 15
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] The death of Izanami, an ancient Japanese goddess : an early report of a case of puerperal fever2006
- Author(s)
  Hayakawa S, Komine-Aizawa S, Naganawa S, Shimuzu K, Nemoto N
- Journal Title
  
  Medical Hypotheses 67
  
  Pages: 965-968
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] アロマセラピーに用いられる芳香物質のHIV感染におよぼす影響 -MAGIC-5細胞を用いたin vitroでの検討2006
- Author(s)
  長縄聰, 早川智, 相澤志保子, 清水一史, 北村勝彦, 本多三男, 陳旺全, 鄭瑞棠
- Journal Title
  
  アロマテラピー学雑誌 (印刷中)
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] 産科母子感染のスクリーニングHIV2006
- Author(s)
  有相澤志保子, 早川智
- Journal Title
  
  産婦人科の実際 55巻11号
  
  Pages: 1706-1711
- Data Source
  KAKENHI-PROJECT-17390454
[Journal Article] HIV感染症/AIDS2005
- Author(s)
  早川純子, 早川智, 相澤志保子, 西成田進, 本多三男
- Journal Title
  
  産科と婦人科【特集性感染症の診断・治療と予防】 72(7)
  
  Pages: 884-889
- Data Source
  KAKENHI-PROJECT-17390454
[Patent] ペプチド及びその使用2016
- Inventor(s)
  相澤志保子、本多三男、早川　智
- Industrial Property Rights Holder
  日本大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-24
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 子宮内細菌叢がmaternal-fetal interfaceにおける免疫寛容機序に与える影響の研究2023
- Author(s)
  髙田和秀, Jonghyun Bae, Quang Duy Trinh, 相澤(小峯) 志保子, 早川智
- Organizer
  第31回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07929
[Presentation] TGF-β1はSmad経路を介して不死化絨毛細胞におけるジカウイルス感染を促進する2023
- Author(s)
  トリンズイクアン;パムテイキムニアン;髙田和秀;髙野智圭;相澤(小峯) 志保子; 早川智
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07929
[Presentation] Evaluation of protein expression and phosphorylation of SARS-CoV-2-infected placental tissue in the second trimester by tandem mass tag system.2023
- Author(s)
  Kazuhide Takada、 Quang Duy Trinh、 Shihoko Komine-Aizawa、 Daisuke Tominaga、 Noriko M Tsuji、 Hideto Yamada、 Satoshi Hayakawa
- Organizer
  The 1st Asian Congress for Reproductive Immunology
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Tandem mass tag system によるSARS-CoV-2感染胎盤のプロテオミクス解析2023
- Author(s)
  髙田和秀, Quang Duy Trinh, 相澤(小峯)志保子, 富永大介, 辻典子, 山田秀人, 早川智
- Organizer
  第39回日本産婦人科感染症学会
- Data Source
  KAKENHI-PROJECT-23K07929
[Presentation] 低グルコースストレスはヒト不死化絨毛細胞の風疹ウイルス感染を上昇させる2022
- Author(s)
  Trinh Duy Quang、髙田和秀、 Pham Thi Kim Ngan、髙野智圭、相澤(小峯)志保子、早川智
- Organizer
  第30回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Lactobacillus acidophilus死菌体はCaco-2細胞におけるSARS-CoV-2感染を抑制する2022
- Author(s)
  高田和秀、Trinh Duy Quang、生田稜、相澤(小峯)志保子、辻典子、早川智
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] SARS-CoV-2 に対する胎盤バリアメカニズムの検討2022
- Author(s)
  髙田和秀、山田清香、鈴木真由美、 Trinh Duy Quang、高野智圭、川上香織、佐藤美紀子、小松篤史、岡橋彩、長野伸彦、三澤俊哉、山口恭平、川名敬、森岡一朗、山田秀人、早川智、羽尾裕之、相澤志保子
- Organizer
  第38回日本産婦人科感染症学会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] SARS-CoV-2と胎盤関門2021
- Author(s)
  相澤(小峯)志保子、髙田和秀、Trinh Duy Quang、早川智
- Organizer
  第36回日本生殖免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Recombinant BCG over-expressed Mycobacterium antigens enhanced Ag85B-specific CD8+ T cells.2021
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Matsuo, Mitsuo Honda
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08939
[Presentation] SARS-CoV-2 陽性妊婦における胎盤の免疫・病理学的検討2021
- Author(s)
  髙田和秀, Trinh Duy Quang, 生田稜, 相澤 (小峯)志保子, 羽尾裕之, 加藤紀子, 平田善康, 大森さゆ, 佐藤美紀子, 小松篤史, 長野伸彦, 岡橋彩, 高野智圭, 馬詰武, 下屋浩一郎,川名敬, 森岡一朗, 山田秀人, 早川智
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] 小胞体ストレスは不死化絨毛細胞株の風疹ウイルス感受性を誘導する2021
- Author(s)
  Trinh Duy Quang、髙田和秀、Pham Thi Kim Ngan、高野智圭、相澤(小峯)志保子、早川智
- Organizer
  第36回日本生殖免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] ヒト不死化腸管上皮細胞株を用いたSARS-CoV-2複製に対するLactobacillusの影響の検討2021
- Author(s)
  髙田和秀、Trinh Duy Quang、生田稜、相澤(小峯)志保子、辻典子、早川智
- Organizer
  日本食品免疫学会第17回学術大会
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Recombinant BCG over-expressed Mycobacterium antigens enhanced Ag85B-specific CD8+ T cells2020
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Matsuo, Mitsuo Honda
- Organizer
  The U.S.-Japan Cooperative Medical Sciences Program: The 54th Mycobacteria Panel Meeting（日米医学協力計画抗酸菌症専門部会第54 回日米合同会議）（新型コロナウイルス感染蔓延のため中止）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08939
[Presentation] 小胞体ストレスはヒト不死化絨毛細胞HTR-8 / SVneo細胞を風疹ウイルス感受性にする2020
- Author(s)
  Trinh Duy Quang, 髙田和秀, Pham Thi Kim Ngan, 髙野智圭, 相澤(小峯) 志保子, 早川智
- Organizer
  第28回日本胎盤学会学術集会 2020年10月30日
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Recombinant BCG over-expressed Mycobacterium antigens enhanced Ag85B-specific CD8+ T cells2020
- Author(s)
  Shihoko Komine-Aizawa
- Organizer
  令和元年度日本大学学部連携研究推進シンポジウム　免疫と生殖の共進化　大野　乾　没後20年記念シンポジウム（新型コロナウイルス感染蔓延のため中止。誌上発表）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08939
[Presentation] TGF-β1-induced epithelial-to-mesenchymal transition-like process enhances rubella virus infection to human lung epithelial A549 cells2020
- Author(s)
  Trinh Duy Quang, Pham Thi Kim Ngan, Takada Kazuhide, Okitsu Shoko, Ushijima Hiroshi, Komine-Aizawa Shihoko, Hayakawa Satoshi
- Organizer
  The 94th Annual Meeting of the Japanese Association for Infectious Diseases 2020年8月20日
- Data Source
  KAKENHI-PROJECT-20K08829
[Presentation] Recombinant BCG over-expressed Mycobacterium antigens enhanced Ag85B-specific CD8+ T cells.2019
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Matsuo, Mitsuo Honda
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10035
[Presentation] Recombinant BCG over-expressed Mycobacterium antigens enhanced Ag85B-specific CD8+ T cells.2019
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Matsuo, Mitsuo Honda
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08939
[Presentation] 組換えBCGワクチンによる抗酸菌特異的免疫効果誘導2018
- Author(s)
  相澤（小峯）志保子、早川　智、本多三男
- Organizer
  第3回抗酸菌研究会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 組換えBCGワクチンによる抗酸菌特異的免疫の誘導と結核防御効果2018
- Author(s)
  相澤（小峯）志保子、Jiansheng Jiang、松尾和浩、Lisa F. Boyd、David H. Margulies、本多三男
- Organizer
  第88回実験結核研究会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 組換えBCGワクチンによる抗酸菌特異的免疫効果誘導2018
- Author(s)
  相澤（小峯）志保子、早川　智、本多三男
- Organizer
  第3回抗酸菌研究会
- Data Source
  KAKENHI-PROJECT-17K10035
[Presentation] Induction of antigen 85B-specific CD8+ T cells by recombinant BCG protects against mycobacterial infection2018
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Mizuno, Mitsuo Honda
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] Induction of antigen 85B-specific CD8+ T cells by recombinant BCG protects against mycobacterial infection2018
- Author(s)
  Shihoko Komine-Aizawa, Satoru Mizuno, Satoshi Hayakawa, Kazuhiro Mizuno, Mitsuo Honda
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K10035
[Presentation] Lactobacillus crispatusは腟上皮細胞の再上皮化の促進する2018
- Author(s)
  髙田　和秀、相澤（小峯）志保子、トリン　ズイ　クアン、早川　智
- Organizer
  第35回日本産婦人科感染症学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11160
[Presentation] 組換えBCGワクチンによる抗酸菌特異的免疫の誘導と結核防御効果2018
- Author(s)
  相澤（小峯）志保子、Jiansheng Jiang、松尾和浩、Lisa F. Boyd、David H. Margulies、本多三男
- Organizer
  第88回実験結核研究会
- Data Source
  KAKENHI-PROJECT-17K10035
[Presentation] 非結核性抗酸菌防御能に優れた組換えBCGワクチンの開発2017
- Author(s)
  相澤（小峯）志保子、本多三男、早川　智
- Organizer
  第91回日本感染症学会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 抗酸菌由来Ag85Bの抗原提示における免疫学的解析2017
- Author(s)
  相澤（小峯）志保子、本多三男、早川　智
- Organizer
  第87回実験結核研究会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] Induction of CD8+- H2-Kd-restricted, antigen 85B-specific T cells by recombinant BCG protects against mycobacterial infection2017
- Author(s)
  Shihoko Komine-Aizawa, Jiansheng Jiang, Satoshi Hayakawa, Kazuhiro Matsuo, Lisa F. Boyd, David H. Margulies, Mitsuo Honda
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017) 第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] Induction of CD8+- MHC-I-restricted, antigen-specific T cells by recombinant BCG protects against mycobacterial infection2017
- Author(s)
  Shihoko Komine-Aizawa, Jiansheng Jiang, Satoshi Hayakawa, Kazuhiro Matsuo, Lisa F. Boyd, David H. Margulies, Mitsuo Honda
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 炎症誘導蛋白High Mobility Group Box 1 はヒト初代T細胞でHIVの複製を促進する2017
- Author(s)
  トリン　ズイ　クアン、髙田　和秀、相澤（小峯）志保子、早川　智
- Organizer
  第32回日本生殖免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K11160
[Presentation] デーデルライン桿菌は腟上皮細胞のre-epithelializationを促進する2017
- Author(s)
  髙田　和秀、相澤（小峯）志保子、トリン　ズイ　クアン、早川　智
- Organizer
  第32回日本生殖免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K11160
[Presentation] MHC Class I presentation by highly functional epitope peptide of M. tuberculosis shared among mycobacterial antigen 85 complex2016
- Author(s)
  相澤志保子、早川　智、本多三男
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 抗結核CD8T細胞エピトープ分子の特性と組換えワクチン開発の試み2016
- Author(s)
  相澤志保子、早川　智、本多三男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 細胞傷害性T細胞を誘導可能な新規組換えBCGワクチンの開発2016
- Author(s)
  相澤志保子、早川　智、本多三男
- Organizer
  第44回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-16K09946
[Presentation] 性ホルモンとToll-like receptorリガンドのHaCaT細胞における遊走及びEpithelial-Mesenchymal Transitionに対する影響(2015
- Author(s)
  高田和秀、廣畑直子, Trinh Quang, 相澤志保子, 早川智
- Organizer
  第43回日本臨床免疫学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24390382
[Presentation] 生殖免疫学領域における動物モデル2014
- Author(s)
  相澤志保子
- Organizer
  日本臨床免疫学会
- Place of Presentation
  京王プラザホテル（東京・新宿区）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24592485
[Presentation] 2009年に発生した新型インフルエンザウイルス(A/H1N1)の胎盤傷害性について2013
- Author(s)
  相澤志保子、早川　智
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24390382
[Presentation] CBA/J×DBA/2J反復流産マウスモデルに対する新たな治療戦略と免疫学的解析2012
- Author(s)
  相澤(小峯)志保子, 早川智
- Organizer
  第64回日本産科婦人科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21592114
[Presentation] アロ免疫による流産マウスモデルに対する新たな治療戦略と免疫学的解析2012
- Author(s)
  相澤志保子、早川　智
- Organizer
  第40回日本臨床免疫学会総会
- Place of Presentation
  東京（新宿）
- Data Source
  KAKENHI-PROJECT-24592485
[Presentation] CBA/J×DBA/2J流産マウスモデルにおける"当帰芍薬散""柴苓湯"の効果2011
- Author(s)
  相澤(小峯)志保子, 早川智
- Organizer
  第29回産婦人科漢方研究会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21592114
[Presentation] 流産マウスモデルにおける新しい流産予防治療の開発2011
- Author(s)
  相澤(小峯)志保子, 早川智
- Organizer
  第26回日本生殖免疫学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21592114
[Presentation] ブタ由来新型インフルエンザウイルス(H1N1)が初期胎盤絨毛に与える影響2011
- Author(s)
  相澤志保子、早川智
- Organizer
  第63回日本産科婦人科学会総会・学術集会(東日本大震災の影響で2011 年8 月29 日に延期となった)
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-04-15
- Data Source
  KAKENHI-PROJECT-21791574
[Presentation] The therapeutic potential of the recombinant antigen from Dirofilaria immitis(rDiAg) for immune mediated pregnancy loss2010
- Author(s)
  Shihoko Komine-Aizawa, Yasuyuki Izumi, and Satoshi Hayakawa
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21592114
[Presentation] The therapeutic potential of the recombinant antigen from Dirofilaria immitis (rDiAg) for immune mediated pregnancy loss2010
- Author(s)
  Shihoko Komine-Aizawa, Yasuyuki Izumi, Satoshi Hayakawa
- Organizer
  14th International Congress of Immunology. Workshop
- Place of Presentation
  Kobe
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21592114
[Presentation] グラム陽性球菌成分は臍帯血リンパ球のThl応答を増強する2008
- Author(s)
  真島洋子, 相澤志保子, 木根淵猛, 唐崎美喜, 千島史尚, 山本樹生, 早川智
- Organizer
  第23回日本生殖免疫学会
- Place of Presentation
  富山
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] HIVの母子感染HIV垂直感染における胎盤関門の解析2008
- Author(s)
  相澤志保子, 泉泰之, 長縄総, 本多三男, 木村勝彦, 稲葉憲之, 山本直樹, 早川智
- Organizer
  第82日本感染症学会
- Place of Presentation
  島根
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] ヒト絨毛癌細胞株BeWoに歯周病原菌由来LPSが与える影響(2008
- Author(s)
  相澤志保子, 真島洋子, 早川智
- Organizer
  第60回日本産科婦人科学会
- Place of Presentation
  横浜
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] HIVの母子感染HIV垂直感染における胎盤関門の解析2008
- Author(s)
  相澤志保子, 泉泰之, 長縄聡, 本多三男, 北村勝彦, 稲葉憲之, 山本直樹, 早川智
- Organizer
  第82回日本感染症学会
- Place of Presentation
  島根
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] TLRを介した刺激はCD56陽性大穎粒NK, NKT細胞株のIFN-γ産生を調節する2008
- Author(s)
  真島洋子, 鈴木美喜, 木根渕猛, 千島史尚, 相澤志保子, 泉泰之, 早川智
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] 当帰芍薬散は内在性レトロウイルスenv遺伝子産物syncytinを介して絨毛細胞株BeWoの分化とhCG産生を促進する2007
- Author(s)
  相澤(小峯)志保子, 真島洋子、野呂知加子、早川智
- Organizer
  第27回産婦人科漢方研究会
- Place of Presentation
  大阪
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] Stimuli through Toll like receptor(TLR)3 and 9 affect human chorionic gonadotropin(hCG)production by a choriocarcinoma cell line.2007
- Author(s)
  Shihoko Komine-Aizawa, Hiroko Majima and Satoshi Hayakawa
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] ヒト絨毛細胞株BeWoに歯周病原菌由来LPSが与える影響2007
- Author(s)
  相澤志保子、真島洋子、早川智、安孫子宣光
- Organizer
  第22回日本生殖免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] TLRを介した刺激はCD56陽性大顆粒NK,NKT細胞株のIFN-γ産生を調節する2007
- Author(s)
  真島洋子, 鈴木美喜, 木根渕猛, 千島史尚, 相澤志保子, 泉泰之, 早川智
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] 甘遂 (カンツィ) 由来の新規テルペノイド誘導体の抗HIV活性の検討2006
- Author(s)
  長縄聰, 菱山和義, 松崎圭一, 相澤志保子, 真島洋子, 北村勝彦, 北中進, 早川智
- Organizer
  第20回日本エイズ学会
- Place of Presentation
  東京
- Year and Date
  2006-11-30
- Data Source
  KAKENHI-PROJECT-17390454
[Presentation] 女性の各ライフステージでの感染症の実態と対策 HIVと抗酸菌感染症
- Author(s)
  相澤志保子, 本多三男, Trinh Duy Quang, 早川智
- Organizer
  第29回日本女性医学会
- Place of Presentation
  東京都　千代田区　都市センターホテル
- Year and Date
  2014-11-01 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-24390382
[Presentation] 未病と自然炎症粘膜における免疫応答と漢方　メタゲノムの視点から
- Author(s)
  早川智, 相澤志保子, 伊田英恵, 陳旺全, 鄭瑞棠
- Organizer
  第65回日本東洋医学会シンポジウム
- Place of Presentation
  東京都　千代田区　東京フォーラム
- Year and Date
  2014-06-27 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-24390382

1. HAYAKAWA Satoshi (30238084)

# of Collaborated Projects: 15 results

# of Collaborated Products: 108 results
2. TRINH DuyQuang (90647190)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
3. HONDA Mitsuo (20117378)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
4. IZUMI Yasuyuki (50459872)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. 川名敬 (60311627)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 高田和秀 (60848711)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. NAGANAWA Satoshi (40445747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
8. NEMOTO Norimichi (80096875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. KITAMURA Katsuhiko (30195284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. SAITOH Shigeru (30175351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YAMAMOTO Naoki (00094053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. INABA Noriyuki (70114238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MASUDA Hideki (40173752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKAHASHI Yasuo (30339329)

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15. USHIJIMA Hiroshi (10091068)

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16. SUZAKI Ai (90251454)

# of Collaborated Projects: 1 results

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17. 神谷茂 (10177587)

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18. 大谷郁 (30377410)

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19. 森岡一朗 (80437467)

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20. 舛廣善和 (00336083)

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21. 権寧博 (80339316)

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22. 樽本憲人 (00746993)

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23. 山田秀人 (40220397)

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24. 木村正 (90240845)

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25. 相澤修 (10645899)

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26. 竹田善紀 (50825239)

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27. 高野智圭 (50845310)

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28. 荒木慶彦 (70250933)

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29. 小林剛

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30. 牛島広治

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# of Collaborated Products: 4 results
31. 太向勇

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32. 堀江真史

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33. 三木敏生

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Aizawa Shihoko 相澤 志保子

AIZAWA Shihoko 相澤 志保子

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組換えBCGとDNAワクチンのプライムブースト接種法による新たなワクチン開発の試みPrincipal Investigator

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Study on cellular immunity against Mycobacterium and development of new vaccinePrincipal Investigator

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Development of novel recombinant BCG vaccine and its immunological analysisPrincipal Investigator

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Immunological analysis of immune-mediated pregnancy loss.Principal Investigator

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Placenta as a target of influenza virus infectionPrincipal Investigator

Aizawa Shihoko 相澤志保子

AIZAWA Shihoko 相澤志保子

[Book] 妊娠と感染症, HIV (鈴木光明吉村泰典編産婦人科専門医に聞く最新の臨床)2007

[Book] 妊娠と感染症 HIV 産婦人科専門医に聞く最新の臨床(鈴木光明吉村泰典編)2007