TAKAHASHI NAOKI 高橋直生

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TAKAHASHI Naoki 高橋直生

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Researcher Number	30377460
Other IDs
Affiliation (Current)	2022: 福井大学, 学術研究院医学系部門(附属病院部), 助教
Affiliation (based on the past Project Information) *help	2016 – 2021: 福井大学, 学術研究院医学系部門(附属病院部), 助教 2007 – 2015: 福井大学, 医学部附属病院, 助教 2011: 福井大学, 医学部・附属病院, 助教 2008: 福井大学, 医学部・附属病院, 助教 2005 – 2006: 福井大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Laboratory medicine / Basic Section 53040:Nephrology-related / Kidney internal medicine
Keywords	Principal Investigator 糖尿病性腎症 / 低酸素 / ポドサイト / IgM / 形質細胞 / 尿細管性アシドーシス / 原発性胆汁性胆管炎 / 尿細管間質性腎炎 / ファンコニー症候群 / 糖尿病 … More / 睡眠時無呼吸症候群 / 糖尿病モデルマウス / ob/ob / BTBR / 腎病理 / Fancnoni症候群 … More Except Principal Investigator 急性腎障害 / 酸化ストレス / チオレドキシン / バイオマーカー / マクロファージ / 尿中チオレドキシン / PAI-1 / VEGF / MCP-1 / 糖尿病性腎症 / db / dbマウス / 慢性低酸素 / 糸球体硬化 / 結節性硬化 / 微小血管瘤 / メサンギオリーシス / CD34 / 高血糖 / 糖尿病 / 糖尿病性腎症モデルマウス / 進行性腎障害 / 尿細管間質障害 / 血管透過性因子 / 尿細管上皮細胞 / エキソゾーム分画 / 尿中マーカー / 人工心肺手術 / ヘテロマルチマー / ＦＳＰ１ / ＲＡＧＥ / ポドサイト / メサンギウム細胞 / FSP1 / RAGE / 虚血性低酸素 / 進行性腎疾患 / 低酸素飼育マウス / cDNAアレイ / 尿細管障害 / 低気圧性低酸素 / マウス / 培養ヒト近位尿細管細胞 / ケモカイン / 低酸素 / 腎線維化 / 貧血マウス / TGF-β1 / ischemic hypoxia / progressive kidney diseases / hypobaric hypoxic / milieu / cDNA array / renal tubular cells / レドックス破綻 / 細胞周期G2/M期停止 / レドックス / G2/M細胞周期停止 / AKI-to-CKD transition / 慢性腎臓病 / 細胞周期 Less

レドックス制御破綻に着目した急性腎障害の新たな発症修復メカニズムの解明
- Principal Investigator
  
  糟野健司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Fukui
Establishment of disease concept of new systemic disease "IgM-positive plasma cell related disease"Principal Investigator
- Principal Investigator
  
  高橋直生
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Fukui
Elucidation of the Pathogenesis and Repair Mechanism of Acute Kidney Injury by a New Approach from Redox Dysregulation
- Principal Investigator
  
  Kasuno Kenji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Fukui
Establishment and elucidation of the mechanisms of new renal pathological entity "IgM-positive plasma cell tubulointerstitial nephritis''Principal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
Linkage of sleep apnea syndrome and diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  Takahashi Naoki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Development of a redox biological reaction-based diagnostic method at bedside for oxidative stress
- Principal Investigator
  
  KASUNO Kenji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Role of secreted FSP1 in the progression of diabetic nephropathy, especially in podocyte-mesangial crosstalk.
- Principal Investigator
  
  IWANO MASAYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Fukui
新規尿検査としての尿中エキソゾーム分画中腎症マーカー蛋白の検出
- Principal Investigator
  
  吉田治義
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Podocyte injury induced by chronic hypoxia in diabetic db/db micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Naoki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Study on chronic hypoxia-related advancement factor in a mouse model of diabetic nephropathy
- Principal Investigator
  
  YOSHIDA Haruyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui
Studies on the Pathogenesis and the Modulation of Kidney Diseases in Hypoxic Milieu
- Principal Investigator
  
  YOSHIDA Haruyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Fukui

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All Journal Article Presentation Book

[Book] Hospitalist2018
- Author(s)
  高橋直生　岩野正之
- Total Pages
  10
- Publisher
  メディカル・サイエンス・インターナショナル
- ISBN
  9784895929530
- Data Source
  KAKENHI-PROJECT-17K09692
[Journal Article] Development of Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody-positive Necrotizing Crescentic Glomerulonephritis in an Elderly Patient with Immunological Kidney Disease2021
- Author(s)
  Haruyoshi Yoshida, Naoki Takahashi, Takayasu Horiguchi, Hiroki Yasuhara, Tokuharu Tanaka, Yuhao Chen, Toshikazu Takasaki, Hitokazu Tsukao, Michiko Yoshida, Satoshi Kawakami, Makoto Ohta, Hironobu Naiki, Satoshi Konishi, Isao Ito, Masayuki Iwano
- Journal Title
  
  Internal Medicine
  
  Volume: 60 Issue: 24 Pages: 3927-3935
- DOI
  10.2169/internalmedicine.7252-21
- NAID
  130008129501
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-21K06967
[Journal Article] Tubulointerstitial nephritis with IgM-positive plasma cells in an elderly woman diagnosed by a renal biopsy and treated with corticosteroid therapy2021
- Author(s)
  Yuki Miyaguchi, Satomi Kato, Manami Saito, Yohei Inoue, Kento Ieda, Shie Ichihara, Mizuho Kobayashi, Naoki Takahashi, Masayuki Iwano, Norihiro Suga
- Journal Title
  
  Jpn J Geriat
  
  Volume: 58 Issue: 4 Pages: 630-636
- DOI
  10.3143/geriatrics.58.630
- NAID
  130008126324
- ISSN
  0300-9173
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08630
[Journal Article] PPAR-δ activation reduces cisplatin-induced apoptosis via inhibiting p53/Bax/caspase-3 pathway without modulating autophagy in murine renal proximal tubular cells2021
- Author(s)
  Shan J, Kimura H, Yokoi S, Kamiyama K, Imamoto T, Takeda I, Kobayashi M, Mikami D, Takahashi N, Kasuno K, Sugaya T, Iwano M.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 25 Pages: 598-607
- DOI
  10.1007/s10157-021-02039-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07844, KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-20H03696
[Journal Article] Glucocorticoid-dependent Tubulointerstitial Nephritis with IgM-positive Plasma Cells Presenting with Intracellular Crystalline Inclusions within the Rough Endoplasmic Reticulum2021
- Author(s)
  Masanori Minato, Taichi Murakami, Naoki Takahashi, Hiroyuki Ono, Kenji Nishimura , Masanori Tamaki, Kojiro Nagai, Hideharu Abe, Masayuki Iwano, Kensuke Joh, Toshio Doi
- Journal Title
  
  Internal Medicine
  
  Volume: - Issue: 19 Pages: 3129-3136
- DOI
  10.2169/internalmedicine.7118-21
- NAID
  130008095975
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08630
[Journal Article] IgA Vasculitis Developed as an Adverse Effect of Tofacitinib Taken for Rheumatoid Arthritis2020
- Author(s)
  Itoh I, Kasuno K, Yamamoto C, Takahashi N, Shimizu H, Ojima T, Hayashi S, Kimura H, Iwano M.
- Journal Title
  
  Internal Medicine
  
  Volume: 59 Issue: 6 Pages: 817-821
- DOI
  10.2169/internalmedicine.3668-19
- NAID
  130007808723
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-20K08630
[Journal Article] Preemptive HLA Antibody Screening Prior to Episodic Transplant Renal Biopsy Enables Early Diagnosis and Therapeutic Response in Asymptomatic Chronically Active Antibody-Related Rejection: A Case Report2020
- Author(s)
  Kenji Kasuno, Kazuhisa Nishimori, Seiji Yokoi, Yuki Shimamoto, Sayumi Sakashita, Sayu Morita, Sho Nishikawa, Yudai Nishikawa, Mamiko Kobayashi, Sachiko Fukushima, Daisuke Mikami, Naoki Takahashi, Yumiko Oota, Hideki Kimura, Masayuki Iwano
- Journal Title
  
  Transplant Proc
  
  Volume: 52 Pages: 2750-2753
- DOI
  10.1016/j.transproceed.2020.08.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08630
[Journal Article] Tubulointerstitial Nephritis Cases With IgM-Positive Plasma Cells2020
- Author(s)
  Matsuoka-Uchiyama Natsumi、Tsuji Kenji、Fukushima Kazuhiko、Kitamura Shinji、Uchida Haruhito A.、Sugiyama Hitoshi、Takahashi Naoki、Iwano Masayuki、Wada Jun
- Journal Title
  
  Kidney Int Rep
  
  Volume: 5 Pages: 1576-1580
- DOI
  10.1016/j.ekir.2020.06.010
- NAID
  120006890014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08679, KAKENHI-PROJECT-20K08630
[Journal Article] Analytical and clinical validation of rapid chemiluminescence enzyme immunoassay for urinary thioredoxin, an oxidative stress-dependent early biomarker of acute kidney injury2020
- Author(s)
  Yokoi S, Kasuno K, Nishimori K, Nishikawa S, Nishikawa Y, Morita S, Kobayashi M, Fukushima S, Mikami D, Takahashi N, Oota Y, Kimura H, Soya Y, Kimata S, Nishimura K, Ono T, Muso E, Yoshida H, Yodoi J, Iwano M.
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 507 Pages: 271-279
- DOI
  10.1016/j.cca.2020.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-20K07844, KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-20H03696
[Journal Article] Chronic hypoxia exacerbates diabetic glomerulosclerosis through mesangiolysis and podocyte injury in db/db mice2020
- Author(s)
  Naoki Takahashi, Haruyoshi Yoshida, Hideki Kimura, Kazuko Kamiyama, Tomomi Kurose, Hidehiro Sugimoto, Toshio Imura, Seiji Yokoi, Daisuke Mikami, Kenji Kasuno, Hiroyuki Kurosawa, Yoshiaki Hirayama, Hironobu Naiki, Masanori Hara, Masayuki Iwano.
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: - Pages: 1678-1688
- DOI
  10.1093/ndt/gfaa074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-20K07844, KAKENHI-PROJECT-20K08630, KAKENHI-PROJECT-20H03696
[Journal Article] β-Hydroxybutyrate, a ketone body, reduces the cytotoxic effect of cisplatin via activation of HDAC5 in human renal cortical epithelial cells2019
- Author(s)
  Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Morikawa Y, Yokoi S, Takahashi N, Kasuno K, Taniguchi T, Iwano M.
- Journal Title
  
  Life Sciences
  
  Volume: 222 Pages: 125-132
- DOI
  10.1016/j.lfs.2019.03.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-18K06946, KAKENHI-PROJECT-16K19012, KAKENHI-PROJECT-19K09794
[Journal Article] Elevated Levels of Urinary Extracellular Vesicle Fibroblast-Specific Protein 1 in Patients with Active Crescentic Glomerulonephritis2019
- Author(s)
  Morikawa Y, Takahashi N, Kamiyama K, Nishimori K, Nishikawa Y, Morita S, Kobayashi M, Fukushima S, Yokoi S, Mikami D, Kimura H, Kasuno K, Yashiki T, Naiki H, Hara M, Iwano M.
- Journal Title
  
  Nephron
  
  Volume: 141 Pages: 177-187
- DOI
  10.1159/000495217
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-15H04836, KAKENHI-PROJECT-16K08931
[Journal Article] Tubulointerstitial Nephritis with IgM-Positive Plasma Cells2017
- Author(s)
  Takahashi N,　Kimura H et al
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 28 Pages: 3688-3698
- DOI
  10.1681/asn.2016101074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08931, KAKENHI-PROJECT-17K08656, KAKENHI-PROJECT-17K09692, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26293201, KAKENHI-PROJECT-15H04836, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05170, KAKENHI-PROJECT-15K09252
[Journal Article] A heterozygous female with Fabry disease due to a novel alpha-galactosidase A mutation exhibits a unique synaptopodin distribution in vacuolated podocytes2015
- Author(s)
  Takahashi N, Yokoi S, Kasuno K, Kogami A, Tsukimura T, Togawa T, Saito S, Ohno K, Hara M, Kurosawa H, Hirayama Y, Kurose T, Yokoyama Y, Mikami D, Kimura H, Naiki H, Sakuraba H, Iwano M.
- Journal Title
  
  Clin. Nephrol.
  
  Volume: 83 Pages: 301-308
- DOI
  10.5414/cn108317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590686, KAKENHI-PROJECT-25860399, KAKENHI-PROJECT-25293094
[Journal Article] Renal redox dysregulation in AKI: application for oxidative stress marker of AKI.2014
- Author(s)
  Kasuno K, Iwano M, et al.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 307 Pages: 1342-1351
- DOI
  10.1152/ajprenal.00381.2013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390216, KAKENHI-PROJECT-24590686, KAKENHI-PROJECT-24591193, KAKENHI-PROJECT-25460784
[Journal Article] Telmisartan, a possible PPAR-δ agonist, reduces TNF-α-stimulated VEGF-C production by inhibiting the p38MAPK/HSP27 pathway in human proximal renal tubular cells.2014
- Author(s)
  Kimura H, Iwano M, et al
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 454 Pages: 320-327
- DOI
  10.1016/j.bbrc.2014.10.077
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390216, KAKENHI-PROJECT-24590686, KAKENHI-PROJECT-24591193
[Journal Article] Telmisartan activates endogenous peroxisome proliferator- activated receptor-δand may have anti-fibrotic effects in human mesangial cells2014
- Author(s)
  Mikami D, Iwano M, et al.
- Journal Title
  
  Hypertens Res
  
  Volume: 37 Pages: 422-31
- DOI
  10.1038/hr.2013.157
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390216, KAKENHI-PROJECT-24590686, KAKENHI-PROJECT-24591193, KAKENHI-PROJECT-24659415
[Journal Article] Significance of renal biopsy in patients with presumed diabetic nephropathy2013
- Author(s)
  Harada K, Akai Y, Sumida K, Yoshikawa M, Takahashi H, Yamaguchi Y, Kubo A, Iwano M, Saito Y.
- Journal Title
  
  J Diabetes Invest
  
  Volume: 4 Pages: 88-93
- DOI
  10.1111/j.2040-1124.2012.00233.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659415
[Journal Article] Severe intraglomerular detachment of podocytes in a Gitelman syndrome patient.2012
- Author(s)
  Naoki Takahashi, Hideki Kimura, Shinichi Mizuno, Masanori Hara, Yoshiaki Hirayama, Hiroyuki Kurosawa, Shouji Tsutaya, Minoru Yasujima, Seiji Yokoi, Daisuke Mikami, Kenji Kasuno, Hironobu Naiki, Masayuki Iwano and Haruyoshi Yoshida
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: (in press) Pages: 16-16
- DOI
  10.1007/s10157-012-0624-4
- NAID
  10030808799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-24590686
[Journal Article] Smaller LDL size as a possible risk factor for the prevalence of coronary artery diseases in hemodialysis patients-Associations of CETP and the hepatic lipase gene polymorphism with LDL size2011
- Author(s)
  Kimura H, Miyazaki R, Imura T, Masunaga S, Shimada A, Mikami D, Kasuno K, Takahashi N, Hirano T, Yoshida H
- Journal Title
  
  Nephrology
  
  Volume: 16 Pages: 558-566
- DOI
  10.1111/j.1440-1797.2011.01454.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-21591024
[Journal Article] 腎障害をきたす全身疾患-最新の進歩III.パラプロテイン血症2.アミロイドーシス2011
- Author(s)
  高橋直生, 木村秀樹, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 1282-1288
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Smaller LDL size as a possible risk factor for the prevalence of coronary artery diseases in hemodialysis patients-Associations of CETP and the hepatic lipase gene polymorphism with LDL size.2011
- Author(s)
  Kimura H, Miyazaki R, Imura T, Masunaga S, Shimada A, Mikami D, Kasuno K, Takahashi N, Hirano T, Yoshida H.
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] レドックス制御因子チオレドキシン研究の臨床展開2011
- Author(s)
  糟野健司, 木村秀樹, 高橋直生, 三上大輔, 横山由就, 信川泰成, 重見研司, 吉田治義
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 189-195
- NAID
  10029427045
- Data Source
  KAKENHI-PROJECT-22659113
[Journal Article] 腎臓病の扉をひらくキーワードレドックス制御因子チオレドキシン研究の臨床展開2011
- Author(s)
  糟野健司、木村秀樹、高橋直生、三上大輔、横山由就、信川泰成、重見賢治、吉田治義
- Journal Title
  
  臨床病理
  
  Volume: 59 Pages: 189-195
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Glucocorticoid enhances hypoxia- and/or transforming growth factor-ss-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells.2011
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Kasuno K, Takahashi N, Yoshida H.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells2011
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Kasuno K, Takahashi N, Yoshida H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 24-40
- DOI
  10.1007/s10157-010-0351-7
- NAID
  10029004358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 腎障害をきたす全身疾患-最新の進歩III.パラプロテイン血症2011
- Author(s)
  高橋直生、木村秀撒、吉田治義、内木宏延
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 100 Pages: 1282-1288
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Osteoprotegerin(OPG)2010
- Author(s)
  高橋直生、木村秀樹、糟野健司、吉田治義
- Journal Title
  
  日本臨床増刊号
  
  Volume: 68 Pages: 152-155
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 特集:広範囲血液・尿生化学検査,免疫学的検査(4)-その数値をどう読むか-Osteoprotegerin(OPG)2010
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 風間順一郎, 吉田治義
- Journal Title
  
  日本臨床
  
  Pages: 152-155
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Tubulointerstitial nephritis with IgM-positive plasmacytoid large lymphocyte infiltration in a patient with primary biliary cirrhosis and Sjoegren's syndrome2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Yumiko Kawajiri, Daisuke Mikami, Chie Yamamoto, Kenji Kasuno, Naofumi Imai, Takeshi Kuroda, Shinichi Nishi, Makoto Yamamoto and Haruyoshi Yoshida
- Journal Title
  
  Clin Nephrol
  
  Volume: 74 Pages: 74-80
- DOI
  10.5414/cnp74074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Tubulointerstitial nephritis with IgM-positive plasmacytoid large lymphocyte infiltration in a patient with primary biliary cirrhosis and Sjoegren's syndrome.2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Yumiko Kawajiri, Daisuke Mikami, Chie Yamamoto, Kenji Kasuno, Naofumi Imai, Takeshi Kuroda, Shinichi Nishi, Makoto Yamamoto, Haruyoshi Yoshida.
- Journal Title
  
  Clin Nephrol
  
  Volume: 74 Pages: 74-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] A specific serum IgA antibody discriminates pneumonia from colonization state in patients with Pseudomonas aeruginosa in sputum culture.2010
- Author(s)
  Masanori Yamashita, Yukio Hida, Hidehiro Sugimoto, Naoki Takahashi, Hideki Kimura, Yasuo Nakatomi, Haruvoshi Yoshida, Takeshi Ishizaki.
- Journal Title
  
  J Microbiol Methods
  
  Volume: 198 Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] A specific serum IgA antibody discriminates pneumonia from colonization state in patients with Pseudomonas aeruginosa in sputum culture2010
- Author(s)
  Masanori Yamashita, Yukio Hida, Hidehiro Sugimoto, Naoki Takahashi, Hideki Kimura, Yasuo Nakatomi, Haruyoshi Yoshida and Takeshi Ishizaki
- Journal Title
  
  J Microbiol Methods
  
  Volume: 82 Pages: 198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Dexamethasone enhances basal and TNF-α-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11β- hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 24
  
  Pages: 1759-1765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] ネフローゼ症候群:診断と治療の進歩, III.二次性ネフローゼ症候群の病態3.その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 98 Pages: 75-81
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] 二次性ネフローゼ症候群の病態 3. その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌 98
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Takahashi N, Kimura H, Kitai R, Sato M, Yoneda M, Yamamoto C, Mikami D, Kuriyama M, Kubota T, Itoh H, Yoshida H
- Journal Title
  
  Clin Nephrol 72
  
  Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Takahashi N, Kimura H, Kitai R, Sato M, Yoneda M, Yamamoto C, Mikami D, Kuriyama M, Kubota T, Itoh H, Yoshida H
- Journal Title
  
  Clin Nephrol 72
  
  Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Dexamethasone enhances basal and TNF-α-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11β- hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 24
  
  Pages: 1759-1765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] Dexamethasone enhances basal and TNF-alpha-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11beta-hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells2009
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Kamiyama K, Mikami D, Takahashi N, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 24 Pages: 1759-1765
- DOI
  10.1093/ndt/gfn756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617, KAKENHI-PROJECT-21591024
[Journal Article] 二次性ネフローゼ症候群の病態 3. その他の二次性ネフローゼ症候群2009
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 内木宏延, 吉田治義
- Journal Title
  
  日本内科学会雑誌 98巻
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment2009
- Author(s)
  Naoki Takahashi, Hideki Kimura, Ryuhei Kitai, Mamiko Sato, Makoto Yoneda, Chie Yamamoto, Daisuke Mikami, Masaru Kuriyama, Toshihiko Kubota, Hiroshi Itoh, and Haruyoshi Yoshida
- Journal Title
  
  Clin Nephrol
  
  Volume: 72 Pages: 211-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590617
[Journal Article] A natural PPAR-γ agonist, 15-deoxy-delta 12,14- prostaglandin J2, may act as an enhancer of PAI-1 in human proxymal renal tubular cells under hypoxic and inflammatory conditions2008
- Author(s)
  Kimura H, Li X, Torii K, Okada T, Takahashi N, Fujii H, Ishihara S, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 2496-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Rapid remission of minimal change disease with angiotensin II antagonist treatment in a type 1 diabetic patient with no diabetic nephropathy2008
- Author(s)
  Takahashi N, Kimura H, Nishi S, Yamamoto C, Kawajiri Y, Makino Y, Konoshita T, Miyamori I, Yoshida H
- Journal Title
  
  Nephrol Dial Transplant Plus 5
  
  Pages: 375-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] The clinical significance of abnormal diurnal blood pressure variation in healthy late middle-aged and older adults2008
- Author(s)
  Hamada T, Murata T, Narita K, Takahashi T, Wada Y, Kimura H, Yoshida H
- Journal Title
  
  Bolld Pressure 17
  
  Pages: 134-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] Rapid remission of minimal change disease with angiotensin II antagonist treatment in a type 1 diabetic patient with no diabeticnephropathy.2008
- Author(s)
  Naoki Takahashi
- Journal Title
  
  NDT Plus 1
  
  Pages: 375-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Journal Article] growth of β2-microglobulin-related amyloid fobrils by non-esterified fatty acids at a neutral pH2008
- Author(s)
  Hasegawa K, Tsutsumi-Yasuhara S, Ohhashi Y, Kimura H, Takahashi N, Yoshida H, Miyazaki R, Goto Y, Naiki H
- Journal Title
  
  Biochem J 416
  
  Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590550
[Presentation] レドックス制御破綻を介した新たなAKI-to-CKD transitionのメカニズム2021
- Author(s)
  糟野健司, 横井靖二, 島本侑樹, 坂下紗弓, 西森一久, 西川雄大, 森田紗由, 小林麻美子, 三上大輔, 福島佐知子, 高橋直生, 木村秀樹, 岩野正之
- Organizer
  日本腎臓学会　学術総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] 64Cu-ATSM PET/MRIを用いた腎臓酸化ストレスイメージングと臨床的パラメーターとの比較2021
- Author(s)
  西川雄大, 高橋直生, 坂下紗弓, 島本侑樹, 西森一久, 森田紗由, 小林麻美子, 福島佐知子, 横井靖二, 三上大輔, 木村秀樹, 糟野健司, 辻川哲也, 岡沢秀彦, 岩野正之
- Organizer
  日本腎臓学会　学術総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] Severe diabetic glomerulosclerosis by chronic hypoxic housing of db/db mice; the role of mesangiolysis and podocyte injury with ultrastructural abnormalities2021
- Author(s)
  Naoki Takahashi, Haruyoshi Yoshida, Hideki Kimura, Kazuko Kamiyama, Seiji Yokoi, Kenji Kasuno, Hiroyuki Kurosawa, Yoshiaki Hirayama, Masanori Hara, Masayuki Iwano
- Organizer
  World Congress of Nephrology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] A case of an elderly woman with membranous-like glomerulopathy with masked monoclonal IgG deposits (MGMID) whose renal biopsy revealed renal cell carcinoma.2021
- Author(s)
  Sho Nishikawa, Naoki Takahashi, Sayu Morita, Kazuhisa Nishimori, Sayumi Sakashita, Sachiko Fukushima, Kenji Kasuno and Masayuki Iwano.
- Organizer
  American society of nephrology annual meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] 長期低酸素飼育のdb/dbマウスで糖尿病性糸球体硬化が増悪する2021
- Author(s)
  高橋直生, 吉田治義, 木村秀樹, 上山和子, 横井靖二, 三上大輔, 糟野健司, 黒澤寛之, 平山吉朗, 原正則, 岩野正之
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] Severe diabetic glomerulosclerosis by chronic hypoxic housing of db/db/mice; the role of mesangiolysis and podocyte injury2020
- Author(s)
  Naoki Takahashi Haruyoshi Yoshida, Hideki Kimura, Kazuko Kamiyama, Seiji Yokoi, Kenji Kasuno, Hiroyuki Kurosawa, Yoshiaki Hirayama, Masanori Hara, Masayuki Iwano
- Organizer
  American society of nephrology annual meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] 慢性低酸素はmesangiolysisとポドサイト障害を介しdb/dbマウスの糖尿病性糸球体硬化症を悪化させる2020
- Author(s)
  高橋直生, 吉田治義, 木村秀樹, 上山和子, 横井靖二, 三上大輔, 糟野健司, 黒澤寛之, 平山吉朗, 原正則, 岩野正之
- Organizer
  日本腎臓学会　学術総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] 新規疾患概念Tubulointerstitial Nephritis with IgM-Positive Plasma Cells(IgMPC-TIN)は自己免疫性疾患か?2症例からの検討2020
- Author(s)
  甲田亮, 宮崎慧, 飯野則昭, 高橋直生, 今井直史, 成田一衛
- Organizer
  日本腎臓学会　東部学術大会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] レドックス依存的G2/M細胞周期停止に着目した急性腎障害後の尿細管修復を促進し慢性化を阻止する新規治療戦略の開発2020
- Author(s)
  糟野健司, 横井靖二, 西川翔, 西森一久, 西川雄大, 森田紗由, 小林麻美子, 三上大輔, 高橋直生, 岩野正之
- Organizer
  日本内分泌学会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] 各種腎疾患における64Cu-ATSM PET/MRIを用いた酸化ストレス可視化の試み2020
- Author(s)
  西川雄大, 高橋直生, 西川翔, 西森一久, 森田紗由, 小林麻美子, 福島佐知子, 横井靖二, 三上大輔, 木村秀樹, 糟野健司, 辻川哲也, 岡沢秀彦, 岩野正之
- Organizer
  日本腎臓学会　学術総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] ダイアライザーの膜閉塞を抑制する新たな血液透析回路(recirculation hemodiafiltration;RHDF)の性能評価2020
- Author(s)
  西森一久, 糟野健司, 西村文宏, 西川翔, 西川雄大, 森田紗由, 小林麻美子, 福島佐知子, 横井靖二, 三上大輔, 高橋直生, 木村秀樹, 岩野正之
- Organizer
  日本腎臓学会　学術総会
- Data Source
  KAKENHI-PROJECT-20K08630
[Presentation] Difference between urinary vesicle fibroblast specific protein1 and urinary soluble CD 163 as a marker of crescent formation2019
- Author(s)
  Yukie Morikawa, Naoki Takahashi, Kazuko Kamiyama, Sho Nishikawa, Kazuhisa Nishimori, Yudai Nishikawa, Sayu Morita, Mamiko Kobayashi, Sachiko Fukushima, Seiji Yokoi, Daisuke Mikami, Hideki Kimura, Kenji Kasuno, Masayuki Iwano
- Organizer
  ASN Kidney Week 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] Fanconi syndrome in an elderly patient with membranous nephropathy during treatment with immunosuppressant mizoribine2019
- Author(s)
  Sho Nishikawa, Naoki Takahashi, Yudai Nishikawa, Sayu Morita, Kazuhisa Nishimori, Mamiko Kobayashi, Sachiko Fukushima, Seiji Yokoi, Daisuke Mikami, Hideki Kimura, Kenji Kasuno, Masayuki Iwano
- Organizer
  ASN Kidney Week 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] A unique form of tubulointerstitial nephritis with IgM-positive plasma cells2018
- Author(s)
  Naoki Takahashi, Takako Saeki, Atsushi Komatsuda, Chishio Munemura, Tsuguru Hatta, Ken-ichi Samejima, Yudai Nishikawa, Mamiko Kobayashi, Daisuke Mikami, Kenji Kasuno, Hideki Kimura, Hironobu Naiki, Haruyoshi Yoshida, Ichiei Narita and Masayuki Iwano
- Organizer
  ISN Frontier 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] Elevated levels of urinary extracellular vesicle fibroblast-specific protein 1 in patients with active crescentic glomerulonephritis2018
- Author(s)
  Yukie Morikawa, Naoki Takahashi, Kazuko Kamiyama, Kazuhisa Nishimori, Yudai Nishikawa, Mamiko Kobayashi, Sachiko Fukushima, Seiji Yokoi, Daisuke Mikami, Hideki Kimura, Kenji Kasuno, Masanori Hara and Masayuki Iwano
- Organizer
  ASN Kidney Week 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] A unique form of tubulointerstitial nephritis with IgM-positive plasma cells2018
- Author(s)
  Naoki Takahashi, Takako Saeki, Atsushi Komatsuda, Chishio Munemura, Tsuguru Hatta, Ken-ichi Samejima, Yudai Nishikawa, Mamiko Kobayashi, Daisuke Mikami, Kenji Kasuno, Hideki Kimura, Hironobu Naiki, Haruyoshi Yoshida, Ichiei Narita and Masayuki Iwano
- Organizer
  ISN Frontier Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] Tubulointerstitial nephritis with IgM-positive plasma cells2017
- Author(s)
  Naoki Takahashi, Takako Saeki, Atsushi Komatsuda, Ken-ichi Samejima, Yudai Nishikawa, Kazuhisa Nishimori, Sayu Morita, Mamiko Kobayashi, Yukie Morikawa, Sachiko Fukushima, Seiji Yokoi, Daisuke Mikami, Kenji Kasuno, Hideki Kimura, Ichiei Narita and Masayuki Iwano
- Organizer
  American Society of Nephrology　2017　Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09692
[Presentation] 新規TLR4阻害因子・分泌型FSP1を介したポドサイトーメサンギウム細胞連関2014
- Author(s)
  横井靖二、糟野健司、高橋直生、三上大輔、横山由就、木村秀樹、岩野正之
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659415
[Presentation] 近位尿細菅細胞では、TNF-αは、ｐ38MAPK/ＨＳＰ27経路を介してVEGF-C発現を誘導し、テルミサルタンはこれを抑制する2013
- Author(s)
  木村　秀樹, 三上　大輔, 上山　和子, 高橋　直生, 糟野　健司, 吉田　治義, 岩野　正之
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] Denver Peritoneovenous Shunt（DPS）により透析低血圧が改善した一例2013
- Author(s)
  糟野健司、高橋直生、小練研司、横井靖二、三上大輔、横山由就、木村秀樹、山口明夫、岩野正之
- Organizer
  日本透析医学会学術集会・総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] Telmisartan Activates Endogenous Peroxisome Proliferator-Activated receptor-δ and May Have Anti-Fibrotic Effects in Human Mesangial Cell2013
- Author(s)
  D.Mikami, H.Kimura, K.Kamiyama, K.Torii, S.Yokoi, Y.Yokoyama, N.Takahashi, K.Kasuno, M.Iwano
- Organizer
  ASN Kidney Week
- Place of Presentation
  Georgia World Congress Center (USA)
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] Denver Peritoneovenous Shunt（DPS）により透析低血圧が改善した一例2013
- Author(s)
  糟野健司、高橋直生、小練研司、横井靖二、三上大輔、横山由就、木村秀樹、山口明夫、岩野正之
- Organizer
  第５８回日本透析医学会学術集会・総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] レドックス制御蛋白「チオレドキシン」は酸化ストレスに「より尿細管上皮細胞から尿中に分泌される2013
- Author(s)
  糟野　健司, 高橋　直生, 武曾　恵理, 三上　大輔, 横山　由就, 横井　靖二, 木村　秀樹, 吉田　治義, 岩野　正之
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] 低酸素ストレス性腎障害マーカーとしての尿中ポドカリキシン濃度ーdb/dbマウスを用いてー2013
- Author(s)
  高橋　直生, 糟野　健司, 上山　和子, 黒澤　寛之, 平山　吉朗, 黒瀬　知美, 横井　靖二, 横山　由就, 三上　大輔, 木村　秀樹, 吉田　治義, 原　正則, 岩野　正之
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] 無形成腎と尿路奇形に対し生体腎移植を行ったKallmann症候群の一例2013
- Author(s)
  糟野健司、伊藤秀明、畑郁江、横井靖二、横山由就、三上大輔、高橋直生、木村秀樹、秋野裕信、大嶋勇成、横山修、岩野正之
- Organizer
  日本透析医学会学術集会・総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] Vascular Endothelial Growth Factor-C Production stimulated by TNF-α through p38/HSP27 Pathway and Its therapeutic reduction in Human Proximal Renal Tubular Cells2013
- Author(s)
  H.Kimura, D.Mikami, K.Kamiyama, N.Takahashi, K.Kasuno, H.Yoshida, M.Iwano
- Organizer
  ASN Kidney Week
- Place of Presentation
  Georgia World Congress Center (USA)
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] レドックス制御蛋白「チオレドキシン」は酸化ストレスにより尿細管上皮細胞から尿中に分泌される2013
- Author(s)
  糟野健司、高橋直生、武曾恵理、三上大輔、横山由就、横井靖二、木村秀樹、吉田治義、岩野正之
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] ヒト培養メサンギウム細胞において、テルミサルタンはTGF-β誘導性PAI-1産生をPPAR-∂経路を介して抑制する2013
- Author(s)
  三上　大輔, 木村　秀樹, 上山　和子, 鳥居　国雄, 横山　由就, 横井　靖二, 糟野　健司, 高橋　直生, 岩野　正之
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] 無形成腎と尿路奇形に対し生体腎移植を行ったカルマン症候群の一例2012
- Author(s)
  糟野健司、横井靖二、横山由就、三上大輔、高橋直生、木村秀樹、岩野正之
- Organizer
  第42回日本腎臓学会西部学術大会
- Place of Presentation
  沖縄コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] レドックス制御蛋白「尿中チオレドキシン」の酸化ストレス特異的急性腎障害(AKI)マーカーとしての有用性2011
- Author(s)
  糟野健司, 木村秀樹、高橋直生, 三上大輔, 横山由就、武曾恵里、信川泰成, 重見研司、吉田治義
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 急性腎障害(AKI)の病因別診断に尿中チオレドキシンが有用である2011
- Author(s)
  糟野健司、木村秀樹、高橋直生, 三上大輔, 横山由就, 村瀬詠廉, 横井靖二, 信川泰成, 吉田治義
- Organizer
  第58回日本臨床検査医学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Clinical and molecular-pathological effects of chronic hypoxia on diabetic nephropathy in db/db mice2011
- Author(s)
  Naoki Takahashi
- Organizer
  44th American Society of Nephrology annual meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 慢性低酸素環境におけるdb/dbマウスの糖尿病性腎症の進展機序の解析2011
- Author(s)
  高橋直生
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is an Oxidative Stress Associated Biomarker of Acute Kidney Injury2011
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Yoshinari Yokoyama, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  International Congress on Uremia Research and Toxicity2011
- Place of Presentation
  名古屋
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Urinary Thioredoxin 1 Is an Oxidative Stress-Specific Biomarker of Acute Kidney Injury2011
- Author(s)
  Kenji Kasuno, Eri Muso, Hideki Kimura, Naoki Takahashi, Yasunari Nobukawa, Kiyoshi Mori, Haruyoshi Yoshida
- Organizer
  44th American Society of Nephrology annual meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 血液透析患者の鉄欠乏性貧血における網赤血球ヘモグロビン等量の有用性2011
- Author(s)
  横山由就, 三上大輔, 糟野健司, 高橋直生, 木村秀樹, 山本智恵, 宮城恭子, 宮崎良一, 吉田治義
- Organizer
  第56回日本透析医学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] レドックス制御蛋白「尿中チオレドキシン」の酸化ストレス特異的急性腎障害(AKI)マーカーとしての有用性2011
- Author(s)
  糟野健司、武曾恵理、木村秀樹、高橋直生、三上大輔、横山由就、信川泰成、重見研司、吉田治義
- Organizer
  日本腎臓学会総会2011
- Place of Presentation
  横浜
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Overexpression of Human Liver-Fatty Acid-Binding Protein (L-FABP) Endogenously Enhances Peroxisome Proliferator-Activated Receptor (PPAR)-α Activity Possibly Via Inducing Hepatocyte Nuclear Factor (HNF)-4α in Immortalized Mouse Proximal Renal Tubular Cells (mProx)2011
- Author(s)
  Hideki Kimura, Daisuke Mikami, Kazuko Kamiyama, Kenji Kasuno, Naoki Takahashi, Takeshi Sugaya, Haruyoshi Yoshida
- Organizer
  44th American Society of Nephrology annual meeting
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 血液透析(HD)患者の虚血性心疾患(CAD)の危険因子としての低比重リポ蛋白(LDL)サイズの減少2011
- Author(s)
  木村秀樹,三上大輔, 嶋田章弘、宮崎良一、糟野健司, 高橋直生, 吉田治義、平野勉
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is a Quick and Predictive Biomarker of Acute Kidney Injury.2010
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Tomomi Kurose, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Acceleration of Diabetic Glomerulopathy in db/db Mice in Chronic Hypoxia2010
- Author(s)
  Naoki Takahashi
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 低酸素下のヒト近位尿細管細胞において、グルココルチコイドはPAI-1の産生を増強しVEGFの産生を抑制する2010
- Author(s)
  鳥居国雄, 木村秀樹, 上山和子, 杉本英弘, 岡田敏春, 山野智子, 関口清美, 三上大輔, 糟野健司, 高橋直生, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 腎不全患者を対象とした活性化血小板の測定および血小板凝集能検査との比較検討2010
- Author(s)
  岡田敏春, 高橋直生, 鳥居国雄, 山野智子, 関口清美, 木村秀樹, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Acceleration of Diabetic Glomerulopathy in db/db Mice in Chronic Hypoxia.2010
- Author(s)
  Naoki Takahashi, Hideki Kimura, Kazuko Kamiyama, Tomomi Kurose, Hidehiro Sugimoto, Toshio Imura, Dai suke Mikami, Kenji Kasuno, Haruyo shi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 招待シンポジウム「腎臓病の扉を開くキーワード」尿中チオレドキシンの急性腎障害(AKI)マーカーとしての有用性2010
- Author(s)
  糟野健司、木村秀樹、高橋直生、三上大輔、横山由就、吉田治義
- Organizer
  日本臨床化学会東海北陸支部総会
- Place of Presentation
  福井
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] LDL Size Reduction as a Possible Risk Factor for the Prevalence of Coronary Artery Diseases in Hemodialysis Patients.2010
- Author(s)
  Hideki Kimura, Ryoichi Miyazaki, Shinya Masunaga, Akihiro Shimada, Toshio Imura, Daisuke Mikami, Kenji Kasuno, Naoki Takahashi, Tsutomu Hirano, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Discrete Regulation of VEGF-A and -C in Human Proximal Renal Tubular Cells under Hypoxic and/or Inflammatory Conditions-Inhibitory Effects of Glucocorticoids on Basal and Inducible VEGF Expression.2010
- Author(s)
  Hideki Kimura, Hidehiro Sugimoto, Kazuko Kamiyama, Daisuke Mikami, Kenji Kasuno, Naoki Takahashi, Haruyoshi Yoshida.
- Organizer
  43th American Society of Nephrology annual meeting
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 慢性低酸素環境におけるdb/dbマウスの糖尿病性糸球体硬化の進展2010
- Author(s)
  高橋直生
- Organizer
  第53回日本腎臓学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 慢性低酸素環境におけるdb/dbマウス糖尿病性糸球体硬化の進展2010
- Author(s)
  高橋直生
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-19590550
[Presentation] 慢性低酸素環境におけるdb/dbマウスの糖尿病性糸球体硬化の進展2010
- Author(s)
  高橋直生, 木村秀樹, 糟野健司, 三上大輔, 井村敏雄, 杉本英弘, 吉田治義
- Organizer
  日本腎臓学会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] 高糖、炎症、低酸素状態下の近位尿細管細胞におけるVEGF-A、C発現動態の解析ステロイド作用の検討も含めて2010
- Author(s)
  木村秀樹, 杉本英弘, 上山和子, 三上大輔, 糟野健司, 高橋直生, 吉田治義
- Organizer
  第53回日本腎臓学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] Urinary Thioredoxin Is a Quick and Predictive Biomarker of Acute Kidney Injury2010
- Author(s)
  Kenji Kasuno, Eri Muso, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Tomomi Kurose, Yasunari Nobukawa, Haruyoshi Yoshida.
- Organizer
  米国腎臓学会ASN2010
- Place of Presentation
  米国デンバー
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] Urinary Thioredoxin Is a Predictive Biomarker of Acute Kidney Injury2010
- Author(s)
  Kenji Kasuno, Eri Muso, Junji Yodoi, Kiichi Shirakawa, Daisuke Mikami, Naoki Takahashi, Hideki Kimura, Haruyoshi Yoshida.
- Organizer
  国際腎臓学会ISN2010
- Place of Presentation
  京都
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-22659113
[Presentation] 血液透析患者における低比重リポ蛋白サイズの独立規定因子の解析2010
- Author(s)
  木村秀樹, 宮崎良一, 井村敏雄, 嶋田章弘, 増永慎也, 三上大輔, 糟野健司, 高橋直生, 平野勉, 吉田治義
- Organizer
  第57回日本臨床検査医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590617
[Presentation] The relationship between plasma concentrations of lysophospholipids (LPLs) and dialysis -related amyloidosis in hemodialysis patients2008
- Author(s)
  Takahashi N
- Organizer
  41th Annual Meeting of American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590550
[Presentation] レドックス制御蛋白「尿中チオレドキシン」の酸化ストレス特異的急性腎障害(AKI)マーカーとしての有用性
- Author(s)
  糟野健司、吉田治義、横井靖二、横山由就、三上大輔、高橋直生、木村秀樹、岩野正之
- Organizer
  西日本腎臓研究会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590686
[Presentation] 急性腎障害という新たな概念と生命予後改善に向けた取り組み
- Author(s)
  糟野健司、高橋直生、横井靖二、横山由就、三上大輔、木村秀樹、岩野正之
- Organizer
  福井県内科臨床懇話会
- Place of Presentation
  福井県医師会館
- Invited
- Data Source
  KAKENHI-PROJECT-24590686

1. KIMURA Hideki (20283187)

# of Collaborated Projects: 9 results

# of Collaborated Products: 104 results
2. KASUNO Kenji (60455243)

# of Collaborated Projects: 9 results

# of Collaborated Products: 73 results
3. IWANO Masayuki (20275324)

# of Collaborated Projects: 7 results

# of Collaborated Products: 49 results
4. YOSHIDA Haruyoshi (80135574)

# of Collaborated Projects: 4 results

# of Collaborated Products: 48 results
5. MIKAMI Daisuke (90464586)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. KIMURA Hideki (20283137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAMURA Hajime (70303914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 岡田敏春 (20534027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 内木宏延 (10227704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 高村佳緒里 (20811863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松本英樹 (40142377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUKIMURA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. MORI Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. UWADA Junsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 定清直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 菅井学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 成田一衛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 矢澤隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 谷口隆信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 宇野賀津子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 杉山斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 森俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHASHI NAOKI 高橋 直生

TAKAHASHI Naoki 高橋 直生

Research Projects

Research Products

Co-Researchers

レドックス制御破綻に着目した急性腎障害の新たな発症修復メカニズムの解明

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Establishment of disease concept of new systemic disease "IgM-positive plasma cell related disease"Principal Investigator

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Elucidation of the Pathogenesis and Repair Mechanism of Acute Kidney Injury by a New Approach from Redox Dysregulation

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Establishment and elucidation of the mechanisms of new renal pathological entity "IgM-positive plasma cell tubulointerstitial nephritis''Principal Investigator

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Linkage of sleep apnea syndrome and diabetic nephropathyPrincipal Investigator

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Development of a redox biological reaction-based diagnostic method at bedside for oxidative stress

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Role of secreted FSP1 in the progression of diabetic nephropathy, especially in podocyte-mesangial crosstalk.

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新規尿検査としての尿中エキソゾーム分画中腎症マーカー蛋白の検出

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Podocyte injury induced by chronic hypoxia in diabetic db/db micePrincipal Investigator

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Study on chronic hypoxia-related advancement factor in a mouse model of diabetic nephropathy

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Studies on the Pathogenesis and the Modulation of Kidney Diseases in Hypoxic Milieu

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[Book] Hospitalist2018

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[Journal Article] Development of Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody-positive Necrotizing Crescentic Glomerulonephritis in an Elderly Patient with Immunological Kidney Disease2021

Author(s)

Journal Title

TAKAHASHI NAOKI 高橋直生

TAKAHASHI Naoki 高橋直生