TEJIMA Kazuaki 手島一陽

Researcher Number	30396733
Affiliation (based on the past Project Information) *help	2008: 東大, 医学部附属病院 2007: The University of Tokyo, Faculty of Medicine, Clinical Fellow 2005 – 2007: 東京大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator Ischemic preconditioning / 移植・再生医療 / 酸化ストレス / 虚血再灌流障害 / Kupffer細胞 / NADPH oxidase / 活性酸素ラジカル(ROS) / 脂質過酸化 / 生理活性脂質 / 活性酸素 … More / reactive oxygen species(ROS) / Ischemia / reperfusion injury / Kupffer cells / Oxygen radicals / Oxidative stress / Transplantation and regeneration … More Except Principal Investigator 肝障害 / 肝線維化 / 肝臓病学 / スフィンゴシン1リン酸 / 肝再生 / オートタキシン / リゾフォスファチジン酸 / 肝硬変 / Autotaxin / Lysophosphatidic acid / Liver fibrosis / Liver cirrhosis / Liver damage / 再生医学 / 栄養学 / トランスレイショナルリサーチ / 生理活性 / トランスレイショナルリサー / Regenerative medicine / Nutrition / Translational research / Bioactivity Less

短時間の虚血再潅流による酸化ストレスを介した肝細胞保護作用の制御・機序Principal Investigator
- Principal Investigator
  
  手島一陽
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Elucidation of a role of sphingosine 1-phosphate on liver damage
- Principal Investigator
  
  IKEDA Hitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Modulation by amino acids of the expression of factors produced by hepatic stellate cells : its implication in injured liver
- Principal Investigator
  
  TOMIYA Tomoaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Research for mechanisms of induction of hepatic ischemic tolerance by ischemic preconditioning.Principal Investigator
- Principal Investigator
  
  TEJIMA Kazuaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Elucidation of the clinical significance of autotaxin and lysophosphatidic acid in liver diseases.
- Principal Investigator
  
  IKEDA Hitoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, et. al.
- Journal Title
  
  World J Gastroenterol 13(38)
  
  Pages: 5071-5078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590749
[Journal Article] Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C.2007
- Author(s)
  Watanabe N, Ikeda H, Nakamura K, Obkawa R, Kume Y, Aoki J, Hama K, Okudaira S, Tanaka M, Tonriya T, Yanase M, Tejima K, Nishikawa T, Arai M, Arai H, Omata M, Fujiwara K, Yatomi Y.
- Journal Title
  
  J Clin Gastroenterol 41
  
  Pages: 616-623
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity2007
- Author(s)
  Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M, Fujiwara K, Yatomi Y.
- Journal Title
  
  Life Sci 81
  
  Pages: 1009-1015
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Yanase M, Inoue Y, Nishikawa T, Watanabe N, Ohtomo N, Omata M, Fujiwara K.
- Journal Title
  
  World J Gastroenterol 13
  
  Pages: 5071-5078
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Leucine stimulates HGF production by hepatic stellate cells through mTOR pathway.2007
- Author(s)
  Tomiya T, Nishikawa T, Inoue Y, Ohtomo N, Ikeda H, Tejima K, Watanabe N, Tanoue Y, Omata M. Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages: 176-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Ischemic preconditioning in liver pathophysiology2007
- Author(s)
  Arai M, Tejima K, Ikeda H, Tomiya T, Yanase M, Inoue Y, Nagashima K, Nishikawa T, Watanabe N, Omata M, Fujiwara K.
- Journal Title
  
  J Gastroenterol Hepatol 22 : S1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats.2007
- Author(s)
  Ikeda H, Kume Y, Tejima K, Tomiya T, Nishikawa T, Watanabe N, Ohtomo N, Arai M, Arai C, Omata M, Fujiwara K, Yatomi Y.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 293
  
  Pages: 911-917
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.2007
- Author(s)
  Tomiya T, Yamaoka M, Inoue Y, Nishikawa T, Yanase M, Ikeda H, Tejima K, Nagashima K, Watanabe N, Omata M, Fujiwara K.
- Journal Title
  
  Chemotherapy 53
  
  Pages: 59-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats2007
- Author(s)
  Ikeda H, Kume Y, Tejima K, Tomiya T, Nishikawa T, Watanabe N, Ohtomo N, Arai M, Arai C, Omata M, Fujiwara K, Yatomi Y.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Oxygen radical production by NADPH oxidase in Kupffer cells promotes hepatic ischemic tolerance.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T et al.
- Journal Title
  
  Hepatology International 1(1)
  
  Pages: 215-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590615
[Journal Article] Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Yanase M, moue Y, Nishikawa T, Watanabe N, Ohtomo N, Omata M, fujiwara K.
- Journal Title
  
  World J Gastroenterol 13
  
  Pages: 5071-5078
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Leucine stimulates HGF production by hepatic stellate cells through mTOR pathway.2007
- Author(s)
  Tomiya T, Nishikawa T, Inoue Y, Ohtomo N, Ikeda H, Tejima K, Watanabe N, Tanoue Y, Omata M, Fujiwara K.
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages: 176-180
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Oxygen radical production by NADPH oxidase in Kupffer cells promotes hepatic ischemic tolerance.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, et al.
- Journal Title
  
  Hepatology International 1(1)
  
  Pages: 215-215
- Data Source
  KAKENHI-PROJECT-17590615
[Journal Article] Ischemic preconditioning in liver pathophysiology.2007
- Author(s)
  Arai M, Tejima K, Ikeda H, Tomiya T, et. al.
- Journal Title
  
  J Gastroenterol Hepatol 22(1)
  
  Pages: 65-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590749
[Journal Article] Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats.2007
- Author(s)
  Kume Y, Ikeda H, Inoue M, Tejima K, Tomiya T, Nishikawa T, Watanabe N, et al.
- Journal Title
  
  FEBS Letters 58・18
  
  Pages: 1631-1634
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats2007
- Author(s)
  Kume Y, Ikeda H, Inoue M, Tejima K, Tomiya T, Nishikawa T, Watanabe N, Ichikawa T, Kaneko M, Okubo S, Yokota H, Omata M, Fujiwara K, Yatomi Y
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1631-1634
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Plasma 1ysophosphatidic acid level and serum autotaxin activity are increased in in liver injury in rats in relation to its severity2007
- Author(s)
  Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M Fujiwara K, Yatomi Y.
- Journal Title
  
  Life Sci 81
  
  Pages: 1009-1015
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Stimulation by glutamine and proline of HGF production in hepatic stellate cells2007
- Author(s)
  Nishikawa T, Tomiya T, Ohtomo N, Inoue Y, Ikeda H, Tejima K, Watanabe N, Tanoue Y, Omata M, Fujiwara K.
- Journal Title
  
  Biochem Biophys Res Commun 363
  
  Pages: 978-982
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Effect of rapamycin on hepatocyte function and proliferation induced by growth factors2007
- Author(s)
  Tomiya T, Yamaoka M, Inoue Y, Nishikawa T, Yanase M, Ikeda H, Tejima K, Nagashima K, Watanabe N, Omata M, Fujiwara K.
- Journal Title
  
  Chemotherapy 53
  
  Pages: 59-69
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.2007
- Author(s)
  Tomiya T, Yamaoka M, Inoue Y, Nishikawa T, Yanase M, Ikeda H, Tejima K, et al.
- Journal Title
  
  Chemotherapy 53・1
  
  Pages: 59-69
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Oxygen radical production by NADPH oxidase in Kupffer cells promotes hepatic ischemic tolerance.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T et al.
- Journal Title
  
  Hepatology International 1 (1)
  
  Pages: 215-215
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590615
[Journal Article] Leucine stimulates HGF production by hepatic stellate cells through mTOR pathway2007
- Author(s)
  Tomiya T, Nishikawa T, Inoue Y, Ohtomo N, Ikeda H, Tejima K, Watanabe N, Tanoue Y, Omate, M, Fujiwara K.
- Journal Title
  
  Biochem Biophys Res Common 358
  
  Pages: 176-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Leucine stimulates HGF production by hepatic stellate cells through mTOR pathway2007
- Author(s)
  Tomiya T, Nishikawa T, Inoue Y, Ohtomo N, Ikeda H, Tejima K, et al.
- Journal Title
  
  Biochemical And Biophysical Research Communications (印刷中)
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Stimulation by glutamine and proline of HGF production in hepatic stellate cells.2007
- Author(s)
  Nishikawa T, Tomiya T, Ohtomo N, Inoue Y, Ikeda H, Tejima K, Watanabe N, Tanoue Y, Omata M, Fujiwara K.
- Journal Title
  
  Biochem Biophys Res Commun 363
  
  Pages: 978-982
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats2007
- Author(s)
  Kume Y, Ikeda H, Inoue M, Tejima K, Tomiya T, Nishikawa T, Watanabe N, Ichikawa T, Kaneko M, Okubo S, Yokota H, Omata M, Fujiwara K, Yatomi Y.
- Journal Title
  
  FEBS Lett 581
  
  Pages: 1631-1634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] The herbal medicine inchin-ko-to (TJ-135) induces apoptosis in cultured rat hepatic stellate cells.2006
- Author(s)
  Ikeda H, Nagashima K, Yanase M, Tomiya T, Arai M, Inoue Y, Tejima K, et al.
- Journal Title
  
  Life Sciences 78・19
  
  Pages: 2226-2233
- Data Source
  KAKENHI-PROJECT-18590719
[Journal Article] Hepatocyte preconditioning via activation of NADPH oxidase in Kupffer cells against warm ischemia/reperfusion injury.2005
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Yanase M, et al.
- Journal Title
  
  Hepatology 42(4)
- Data Source
  KAKENHI-PROJECT-17590615
[Journal Article] Hepatocyte preconditioning via activation of NADPH oxidase in Kupffer cells against warm ischemia/reperfusion injury.2005
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Yanase M et al.
- Journal Title
  
  Hepatology 42(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590615
[Presentation] Oxygen radical production by NADPH oxidase in Kupffer cells promotes ischemic tolerance2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Nishikawa T, Watanabe N, Ohtomo N, Yatomi Y, Omata M, Fujiwara K.
- Organizer
  The Asian Pacific Association for the Study of Liver Diseases
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Stimulatory effect of amino acids on HGF production in hepatic stellate cells2007
- Author(s)
  Nishikawa T, Tomiya T, Ohtomo N, Inoue Y, Tanoue Y, Tejima K, Ikeda H, Watanabe N, Omata M, Fujiwara K.
- Organizer
  Asian Pacific Digestive Week 2007
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Chemotherapy-induced HB V reactivation in an HBV carrier showing negative for HBs Ag and HBs Ab2007
- Author(s)
  Ohtomo N, Tomiya T, Sakamoto K, Yoshida H, Kato N, Tejima K, Nishikawa T, Watanabe N, Ikeda H, Omata M.
- Organizer
  The Asian Pacific Association for the Study of Liver Diseases
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Sublethal oxidative stress induces hepatic ischemic tolerance via NADPH oxidase in Kupffer cells2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, Nishikawa T, Watanabe N, Ohtomo N, Yatomi Y, Omata M, Fujiwara K.
- Organizer
  Asian Pacific Digestive Week 2007
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Serum follistatin levels as a marker of hepato-gastrointestinal carcinomas2007
- Author(s)
  Tomiya T, Takabe K, Inoue Y, Tejima K, Ikeda H, Nishikawa T, Watanabe N, Ohtomo N, Omata M, Vale W, Fujiwara K.
- Organizer
  Asian Pacific Digestive Week 2007
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Inhibition of Rho-kinase leads to hepatocyte protection in vitro and in vivo2007
- Author(s)
  Ikeda H, Tomiya T, Tejima K, Nishikawa T, Watanabe N, Ohtomo N, Yatomi Y, Fujiwara K, Omata M.
- Organizer
  The Asian Pacific Association for the Study of Liver Diseases
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity2007
- Author(s)
  Watanabe N, Ikeda H, Tomiya T, Tejima K, Nishikawa T, Ohtomo N, Yatomi Y, Omta M, Fuiwara K.
- Organizer
  Asian Pacific Digestive Week 2007
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Sublethal oxidative stress induces hepatic ischemic tolerance via NADPH oxidase in Kupffer cells.2007
- Author(s)
  Tejima K, Arai M, Ikeda H, Tomiya T, et. al.
- Organizer
  Asian Pacific Digestive Week (APDW)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590749
[Presentation] Pharmacological action of BCAAs on the liver: Possible contribution of BCAAs to the function of hepatic stellate cells.2007
- Author(s)
  Tomiya T, Nishikawa T, Ohtomo N, moue Y, Tejima K, Ikeda H, Watanabe N, Tanoue Y, Omata M, fujiwara K.
- Organizer
  Sixth JSH Single Topic Conference
- Place of Presentation
  Iwate, Japan
- Year and Date
  2007-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Induction of p53-related effector genes may regulate hepatocyte proliferation stimulated by hepatocyte growth factor2007
- Author(s)
  Inoue Y, Tomiya T, Nishikawa T, Ohtomo N, Tanoue Y, Tejima K, Ikeda H, Watanabe N, Omata M, Fujiwara K.
- Organizer
  Asian Pacific Digestive Week 2007
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Pharmacological action of BCAAs on the liver : Possible contribution of BCAAs to the function of hepatic stellate cells2007
- Author(s)
  Tomiya T, Nishikawa T, Ohtomo N, Inoue Y, Tejima K, Ikeda H, Watanabe N, Tanoue Y, Omate. M, Fujiwara K.
- Organizer
  Sixth JSH Single Topic Conference
- Place of Presentation
  Iwate, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] The relationship between serum follistatin levels and liver regeneration in hepatectomized patients2007
- Author(s)
  Tomiya T, Takabe K, Inoue Y, Tejima K, Ikeda H, Nishikawa T, Watanabe N, Ohtomo N, Omata M, Vale W, Fujiwara K.
- Organizer
  The Asian Pacific Association for the Study of Liver Diseases
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Induction of P53-related effector genes may regulate hepatocyte proliferation stimulated by hepatocyte growth factor2006
- Author(s)
  Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Yanase M, Ikeda H, Tejima K, Omata M, Fujiwara K.
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Colorado, USA
- Year and Date
  2006-07-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590719
[Presentation] Induction of P53-related effector genes may regulate hepatocyte proliferation stimulated by hepatocyte growth factor2006
- Author(s)
  Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Yanase M, Ikeda H, Tejima K, Omata M, Fujiwara K.
- Organizer
  FASEB Summer Research Conference
- Place of Presentation
  Snowmass, Colorado, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590719

1. TOMIYA Tomoaki (90227637)

# of Collaborated Projects: 5 results

# of Collaborated Products: 41 results
2. IKEDA Hitoshi (80202422)

# of Collaborated Projects: 5 results

# of Collaborated Products: 42 results
3. YANASE Mikio (50334397)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
4. YATOMI Yutaka (60200523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TEJIMA Kazuaki 手島 一陽

Research Projects

Research Products

Co-Researchers

短時間の虚血再潅流による酸化ストレスを介した肝細胞保護作用の制御・機序Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of a role of sphingosine 1-phosphate on liver damage

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation by amino acids of the expression of factors produced by hepatic stellate cells : its implication in injured liver

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for mechanisms of induction of hepatic ischemic tolerance by ischemic preconditioning.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the clinical significance of autotaxin and lysophosphatidic acid in liver diseases.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells.2007

Author(s)

Journal Title

Data Source

[Journal Article] Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Leucine stimulates HGF production by hepatic stellate cells through mTOR pathway.2007

Author(s)

Journal Title

Data Source

[Journal Article] Ischemic preconditioning in liver pathophysiology2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.2007

Author(s)

Journal Title

Data Source

[Journal Article] Rho-kinase inhibitor prevents hepatocyte damage in acute liver injury induced by carbon tetrachloride in rats2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Oxygen radical production by NADPH oxidase in Kupffer cells promotes hepatic ischemic tolerance.2007

Author(s)

Journal Title

Description

TEJIMA Kazuaki 手島一陽