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Aikata Hiroshi  相方 浩

ORCIDConnect your ORCID iD *help
Researcher Number 30403512
Affiliation (Current) 2022: 広島大学, 医系科学研究科(医), 専門研究員
Affiliation (based on the past Project Information) *help 2019 – 2022: 広島大学, 医系科学研究科(医), 准教授
2017 – 2019: 広島大学, 病院(医), 講師
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords
Principal Investigator
肝癌 / 生活習慣病 / 糖尿病 / 非B型非C型 / 非ウイルス性
Except Principal Investigator
腫瘍免疫 / 肝胆膵がん / ゲノム / オミックス解析 / 分子分類 … More / 分子標的治療 / 免疫 / RNA / プロテオーム / ゲノム解析 / 多層オミックス / がんゲノム / 肝臓がん / 胆道がん / ゲノム不安定 / Pin1 / NASH Less
  • Research Projects

    (5 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (21 People)
  •  Genomic instability and immunology of hepato-biliary cancer

    • Principal Investigator
      中川 英刀
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  NASHの炎症、線維化におけるPin1の役割解明と臨床応用への展開

    • Principal Investigator
      神名 麻智
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hiroshima University
  •  糖脂質代謝異常にフォーカスした多層オミックス解析による糖尿病関連肝発癌機構の解明Principal Investigator

    • Principal Investigator
      相方 浩
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hiroshima University
  •  Multi-omics analysis for hepato-biliary-pancreatic cancers

    • Principal Investigator
      Nakagawa Hidewaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Biomarker for hepatocarcinogenesis in diabetic patientsPrincipal Investigator

    • Principal Investigator
      Aikata Hiroshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Hiroshima University

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Hepatic Arterial Infusion Chemotherapy Combined with Radiation Therapy for Advanced Hepatocellular Carcinoma with Tumor Thrombosis of the Main Trunk or Bilobar of the Portal Vein.2021

    • Author(s)
      Kosaka Y, Kimura T, Kawaoka T, Ogawa Y, Amioka K, Naruto K, Yoshikawa Y, Kikukawa C, Suehiro Y, Yamaoka K, Ando Y, Uchikawa S, Morio K, Nakahara T, Murakami E, Takahashi S, Tsuge M, Hiramatsu A, Imamura M, Chosa K, Awai K, Nagata Y, Chayama K, Aikata H.
    • Journal Title

      Liver Cancer

      Volume: 10 Pages: 151-160

    • DOI

      10.1159/000513706

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07896
  • [Journal Article] Increasing incidence of non-HBV- and non-HCV-related hepatocellular carcinoma: single-institution 20-year study2021

    • Author(s)
      Nagaoki Y, Hyogo H, Ando Y, Kosaka Y, Uchikawa S, Nishida Y, Teraoka Y, Morio K, Fujino H, Ono A, Nakahara T, Murakami E, Yamauchi M, Okamoto W, Kawaoka T, Tsuge M, Hiramatsu A, Miki D, Imamura M, Takahashi S, Chayama K, Aikata H.
    • Journal Title

      BMC Gastroenterology

      Volume: 21(1) Pages: 306-306

    • DOI

      10.1186/s12876-021-01884-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08288, KAKENHI-PROJECT-21K07896, KAKENHI-PROJECT-21K08006
  • [Journal Article] Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab.2020

    • Author(s)
      Kawaoka T, Ando Y, Yamauchi M, Suehiro Y, Yamaoka K, Kosaka Y, Fuji Y, Uchikawa S, Morio K, Fujino H, Nakahara T, Ono A, Murakami E, Takahashi S, Tsuge M, Hiramatsu A, Imamura M, Chayama K, Aikata H.
    • Journal Title

      Hepatol Res.

      Volume: -

    • DOI

      10.1111/hepr.13496

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K09426
  • [Journal Article] Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma2020

    • Author(s)
      Yamauchi M, Ono A, Ishikawa A, Kodama K, Uchikawa S, Hatooka H, Zhang P, Teraoka Y, Morio K, Fujino H, Nakahara T, Murakami E, Miki D, Kawaoka T, Tsuge M, Hiramatsu A, Imanura M, Hayes CN, Fujita M, Nakagawa H, Yusui W, Aikata H, and Chayama K.
    • Journal Title

      Clinical and Translational Gastroenterology

      Volume: 11

    • DOI

      10.14309/ctg.0000000000000179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H04049, KAKENHI-PROJECT-19K09206
  • [Journal Article] Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection2020

    • Author(s)
      Cheng X, Uchida T, Xia Y, Umarova R, Liu CJ, Chen PJ, Gaggar A, Suri V, Mucke MM, Vermehren J, Zeuzem S, Teraoka Y, Osawa M, Aikata H, Tsuji K, Mori N, Hige S, Karino Y, Imamura M, Chayama K, Liang TJ.
    • Journal Title

      J Clin Invest.

      Volume: -

    • DOI

      10.1172/jci135616

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K09426, KAKENHI-PROJECT-17K09427
  • [Journal Article] Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations2020

    • Author(s)
      Fujita M, Yamaguchi R, Hasegawa T, Shimada S, Arihiro K, Hayashi S, Maejima K, Nakano K, Fujimoto A, Ono A, Aikata H, Ueno M, Hayami S, Tanaka H, Miyano S, Yamaue H, Chayama K, Kakimi K, Tanaka S, Imoto S, Nakagawa H.
    • Journal Title

      EBioMedicine.

      Volume: 53 Pages: 102659-102659

    • DOI

      10.1016/j.ebiom.2020.102659

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10675, KAKENHI-PROJECT-18K19426, KAKENHI-PROJECT-18H04049, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-18H02680, KAKENHI-PROJECT-18H02696, KAKENHI-PROJECT-18H03328, KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K09426, KAKENHI-PROJECT-18K19575, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-19K09206
  • [Journal Article] Risk factors for exacerbation of gastroesophageal varices and portosystemic encephalopathy during treatment with nucleos(t)ide analogs for hepatitis B virus-related cirrhosis.2018

    • Author(s)
      Nagaoki Y, Aikata H, Daijyo K, Teraoka Y, Honda F, Nakamura Y, Hatooka M, Morio K, Fujino H, Nakahara T, Kawaoka T, Miki D, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Ochi H, Chayama K.
    • Journal Title

      Hepatol Res

      Volume: 48 Pages: 264-274

    • DOI

      10.1111/hepr.12996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Journal Article] Clinical outcomes of sorafenib treatment failure for advanced hepatocellular carcinoma and candidates for regorafenib treatment in real-world practice.2018

    • Author(s)
      Uchikawa S, Kawaoka T, Aikata H, Kodama K, Nishida Y, Inagaki Y, Hatooka M, Morio K, Nakahara T, Murakami E, Hiramatsu A, Tsuge M, Imamura M, Kawakami Y, Chayama K.
    • Journal Title

      Hepatol Res.

      Volume: 48 Pages: 814-820

    • DOI

      10.1111/hepr.13180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Journal Article] Comparison of clinical outcome of hepatic arterial infusion chemotherapy and sorafenib for advanced hepatocellular carcinoma according to macrovascular invasion and transcatheter arterial chemoembolization refractory status.2018

    • Author(s)
      Kodama K, Kawaoka T, Aikata H, Uchikawa S, Inagaki Y, Hatooka M, Morio K, Nakahara T, Murakami E, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Masaki K, Honda Y, Mori N, Takaki S, Tsuji K, Kohno H, Kohno H, Moriya T, Nonaka M, Hyogo H, Aisaka Y, Chayama K.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: 33 Pages: 1780-1786

    • DOI

      10.1111/jgh.14152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Journal Article] Hepatic arterial infusion chemotherapy followed by sorafenib in patients with advanced hepatocellular carcinoma (HICS 55): an open label, non-comparative, phase II trial.2018

    • Author(s)
      Hatooka M, Kawaoka T, Aikata H, Inagaki Y, Morio K, Nakahara T, Murakami E, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Awai K, Masaki K, Waki K, Kohno H, Kohno H, Moriya T, Nagaoki Y, Tamura T, Amano H, Katamura Y, Chayama K.
    • Journal Title

      BMC Cancer.

      Volume: 18 Pages: 633-633

    • DOI

      10.1186/s12885-018-4519-y

    • NAID

      120006559420

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Journal Article] Comparison of hepatic arterial infusion chemotherapy between 5-fluorouracil-based continuous infusion chemotherapy and low-dose cisplatin monotherapy for advanced hepatocellular carcinoma.2018

    • Author(s)
      Kawaoka T, Aikata H, Kobayashi T, Uchikawa S, Ohya K, Kodama K, Nishida Y, Daijo K, Osawa M, Teraoka Y, Inagaki Y, Honda F, Hatooka M, Morio K, Morio R, Fujino H, Nakahara T, Murakami E, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Baba Y, Awai K, Chayama K.
    • Journal Title

      Hepatol Res.

      Volume: 48 Pages: 1118-1130

    • DOI

      10.1111/hepr.13232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Journal Article] Comparison of Outcome of Hepatic Arterial Infusion Chemotherapy Combined with Radiotherapy and Sorafenib for Advanced Hepatocellular Carcinoma Patients with Major Portal Vein Tumor Thrombosis.2018

    • Author(s)
      Kodama K, Kawaoka T, Aikata H, Uchikawa S, Nishida Y, Inagaki Y, Hatooka M, Morio K, Nakahara T, Murakami E, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Masaki K, Honda Y, Mori N, Takaki S, Tsuji K, Kohno H, Kohno H, Moriya T, Nonaka M, Hyogo H, Aisaka Y, Kimura T, Nagata Y, Chayama K.
    • Journal Title

      Oncology

      Volume: 94 Pages: 215-222

    • DOI

      10.1159/000486483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 非B非C型肝細胞癌における臨床的特徴とスクリーニングにおけるFIB4-indexの可能性について2021

    • Author(s)
      長沖祐子、相方 浩
    • Organizer
      第57回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-21K07896
  • [Presentation] 非B非C型肝細胞癌の背景因子と予後に関する検討2019

    • Author(s)
      長沖祐子,相方浩,茶山一彰
    • Organizer
      第55回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 非B非C型慢性肝疾患患者のアルコール摂取量で群別化した比較検討2018

    • Author(s)
      村上英介,相方浩,茶山一彰
    • Organizer
      第104回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 2型糖尿病を合併する非B非C肝癌の臨床的特徴の解析2018

    • Author(s)
      村上英介,相方浩,茶山一彰
    • Organizer
      JDDW2018
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 非B非C型肝細胞癌の背景因子と予後に関する検討2018

    • Author(s)
      長沖祐子、相方浩、茶山一彰
    • Organizer
      第54回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 非B非C型肝細胞癌の背景因子と予後に関する検討2018

    • Author(s)
      長沖祐子,相方浩,茶山一彰
    • Organizer
      第54回日本肝癌研究会
    • Data Source
      KAKENHI-PROJECT-17K09426
  • [Presentation] 非B非C型肝細胞癌の背景因子とリスク因子に関する検討2018

    • Author(s)
      長沖祐子,相方浩,茶山一彰
    • Organizer
      第54回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17K09426
  • 1.  Nakagawa Hidewaki (50361621)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  中村 透 (70645796)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  井元 清哉 (10345027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  山上 裕機 (20191190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  二階堂 愛 (00383290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  神名 麻智 (10619365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  山本屋 武 (50760013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  浅野 知一郎 (70242063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ABE Hiromi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 10.  IMAMURA Michio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  UENO Masaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  茶山 一彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 13.  三木 大樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  柘植 雅貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  速水 晋也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  藤本 明洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  田中 真二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  島田 周
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  垣見 和宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  林 亮平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  藤田 征志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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