Amita Mitsuyoshi 網田光善

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AMITA Mitsuyoshi 網田光善

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Researcher Number	30420061
Affiliation (based on the past Project Information) *help	2019 – 2021: 国立研究開発法人国立成育医療研究センター, 周産期・母性診療センター, 医員 2016: 国立研究開発法人国立成育医療研究センター, 周産期・母性診療センター, 医員 2014 – 2015: 山形大学, 医学部, 助教 2010 – 2012: 山形大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator Dysmature卵子 / 卵丘細胞・卵子複合体 / 生殖補助医療 / 卵丘細胞卵子複合体 (COC) / 着床前胚染色体異数性検査（PGTA） / 卵丘細胞卵子複合体（COC） / 生殖補助医療（ART） / 着床前胚染色体異数性検査(PGTA) / Dysmature COC / 卵丘細胞卵子複合体(COC) … More / 生殖補助医療(ART) / 妊娠高血圧症 / fibroblast / trophoblast / iPS細胞 / 妊娠高血圧症候群 / 増殖効果 / 子宮内膜上皮 / SERM … More Except Principal Investigator ミトコンドリア / Salubrinal / 小胞体 / salburinal / 若返り / salubrinal / 小胞体ストレス / 加齢卵 / マウス / 酸化ストレス / アポトーシス / メタボローム / カルシウムオシレーション / 細胞内カルシウム / 加齢マウス / ATP / 細胞内カルシウム制御機構 / オートファジー / メタボロミクス / 卵の加齢 Less

Trial to improve ART treatment outcome using Dysmature COC analysisPrincipal Investigator
- Principal Investigator
  
  Amita Mitsuyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  National Center for Child Health and Development
Therapeutic strategy for reproductive aged women by regulation of oxidative stress and endoprasmic reticulum stress
- Principal Investigator
  
  IGARASHI Hideki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
To uncover the pathogenesis of preeclampsia.Principal Investigator
- Principal Investigator
  
  Amita Mitsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Center for Child Health and Development
  Yamagata University
Molecular mechanism of aging-related decline in oocyte quality: a study of metabolomics and autophagy
- Principal Investigator
  
  TAKAHASHI Toshifumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The analysis of molecular mechanism of the precipitation/inhibition of uterine endometrial epithelial cell proliferation by SERMPrincipal Investigator
- Principal Investigator
  
  AMITA Mitsuyoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University

All 2021 2020 2019 2016 2015 2011 2010 Other

All Journal Article Presentation Book

[Book] クエン酸クロミフェンによる子宮内膜増殖抑制作用の分子機構.産婦人科の実際2010
- Author(s)
  網田光善, 高橋俊文, 倉智博久
- Data Source
  KAKENHI-PROJECT-22791513
[Journal Article] Next-Generation Sequencing Reveals Downregulation of the Wnt Signaling Pathway in Human Dysmature Cumulus Cells as a Hallmark for Evaluating Oocyte Quality2020
- Author(s)
  Ryosuke Akino, Daisuke Matsui, Ryouka Kawahara-Miki, Mitsuyoshi Amita, Kuniko Tatsumi, Eri Ishida, Woojin Kang, Shuji Takada, Kenji Miyado, Akihiko Sekizawa,Takakazu Saito,Tomohiro Kono, Hidekazu Saito
- Journal Title
  
  Reproductive Medicine
  
  Volume: 1 Issue: 3 Pages: 205-215
- DOI
  10.3390/reprodmed1030016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09793, KAKENHI-PROJECT-19K09817, KAKENHI-PROJECT-19H01067
[Journal Article] Comparison of syncytiotrophoblast generated from human embryonic stem cells and from term placentas.2016
- Author(s)
  Yabe S, Alexenko AP, Amita M, Yang Y, Schust DJ, Sadovsky Y, Ezashi T, Roberts RM.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 113(19) Issue: 19 Pages: 2598-607
- DOI
  10.1073/pnas.1601630113
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861308
[Journal Article] Cellular and molecular mechanisms of various types of oocyteaging2011
- Author(s)
  Takahashi T, Igarashi H, Amita M, Hara S, Kurachi H.
- Journal Title
  
  Reprod Med Biol
  
  Volume: 10 Issue: 4 Pages: 239-249
- DOI
  10.1007/s12522-011-0099-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591815
[Journal Article] Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture2011
- Author(s)
  Hara S, Takahashi T, Amita M, Igarashi. H, Tsutsumi S, Kurachi. H
- Journal Title
  
  Biol Reprod
  
  Volume: 85(5) Pages: 895-906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791513
[Journal Article] Usefulness of bezafibrate for ovulation induction in clomiphene citrate-resistant polycystic ovary syndrome patients with dyslipidemia a prospective pilot study of seven cases2010
- Author(s)
  Hara. S, Takahashi. T, Amita. M, Igarashi. H, Kurachi. H
- Journal Title
  
  Gynecol Obstet Invest
  
  Volume: 70 Pages: 166-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791513
[Journal Article] Molecular mechanism of poor embryo development in postovulatory aged oocytes
- Author(s)
  Takahashi T, Igarashi H, Amita M, Hara S, Koki M, Kurachi H.
- Journal Title
  
  Mini review
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591815
[Presentation] 卵丘細胞・卵子複合体(COC)の成熟度分類とタイムラプス動態解析を利用したKIDScoreとの関連性2021
- Author(s)
  石田恵理, 巽国子, 網田光善, 内藤奈都子, 岩崎稚子, 小野澤香枝, 兼子恵里香, 勝又翔子, 齊藤隆和
- Organizer
  第66回　日本生殖医学会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K09817
[Presentation] Dysmature卵丘細胞・卵子複合体(COC)由来卵子はART成績不良と関連する2020
- Author(s)
  石田恵理、巽国子、網田光善、小野澤香枝、兼子恵理香、岩崎稚子、齊藤隆和
- Organizer
  第38回　受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K09817
[Presentation] Maturity of cumulus oocyte complex (COC) predicts the outcome of ART. ~ Focus on Dysmature ~2019
- Author(s)
  Mitsuyoshi Amita, Eri Ishida, Kuniko Tatsumi, Yoko Yoshitake, Ryosuke Akino, and Takakazu Saito.
- Organizer
  ASRM 2019 75th ASRM Scientific Congress & Expo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09817
[Presentation] 受精方法による卵丘細胞・卵子複合体(COC)の成熟度とART成績との関連について2019
- Author(s)
  巽国子、石田恵理、網田光善、秋野亮介、清水信義、齊藤隆和、齊藤英和
- Organizer
  第37回　日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K09817
[Presentation] 卵丘細胞・卵子複合体（COC）の成熟度はART成績を予測する指標となる～Dysmature卵子についての検討～2019
- Author(s)
  網田光善　秋野亮介　田中理恵子　齊藤隆和　齊藤英和
- Organizer
  第71回　日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-19K09817
[Presentation] Trophoblast cells generated from human induced pluripotent stem cells (iPSC) derived from umbilical cord by using BMP4 can be disease models for early placental disorders.2015
- Author(s)
  Mitsuyoshi Amita, R. Michael Roberts.
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜 ( 神奈川県横浜市）
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-26861308
[Presentation] 卵加齢メカニズムの新しい概念:マウス卵の加齢に小胞体ストレスが関与する2011
- Author(s)
  五十嵐秀樹、網田光善、原周一郎、堤誠司、高橋俊文、倉智博久
- Organizer
  第63回日本産科婦人科学会
- Place of Presentation
  リーガロイヤルホテル大阪および大阪国際会議場(大阪市)
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22591815
[Presentation] GFP結合ERαを用いた子宮内膜細胞におけるエストロゲン・抗エストロゲン作用の可視化2010
- Author(s)
  網田光善
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22791513
[Presentation] FP結合ERαを用いた子宮内膜細胞におけるエストロゲン・抗エストロゲン作用の可視化2010
- Author(s)
  網田光善, 高橋俊文, 原周一郎, 五十嵐秀樹, 倉智博
- Organizer
  第62回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22791513
[Presentation] FP-ERαを用いた子宮内膜細胞におけるエストロゲン・抗エストロゲン作用の可視化2010
- Author(s)
  網田光善, 高橋俊文, 原周一郎, 五十嵐秀樹, 倉智博久
- Organizer
  第55回日本生殖医学会総会・学術講演会
- Place of Presentation
  徳島市あわぎんホール
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-22791513
[Presentation] Trophoblast cells generated from human induced pluripotent stem cells (iPSC) derived from umbilical cord by using BMP4 can be disease models for early placental disorders.
- Author(s)
  Mitsuyoshi Amita
- Organizer
  ASRM
- Place of Presentation
  ハワイ・コンベンション・センター(アメリカ）
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26861308
[Presentation] Impact of endoplasmic reticulum stress on the postovulatory aging of the mouse oocyte
- Author(s)
  H. Igarashi, T. Takahashi, M. Amita, A. Hasegawa
- Organizer
  ASRM 2014
- Place of Presentation
  Hawaii Convention Center (Honolulu, Hawaii)
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26462474

1. TAKAHASHI Toshifumi (20302292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. IGARASHI Hideki (80333970)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. KURACHI Hirohisa (40153366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. MATSUO Koki (90594317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 斉藤隆和 (00272071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 石田恵理 (00387078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 巽国子 (10534860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 康宇鎮 (10647978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 宮戸健二 (60324844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Amita Mitsuyoshi 網田 光善

AMITA Mitsuyoshi 網田 光善

Research Projects

Research Products

Co-Researchers

Trial to improve ART treatment outcome using Dysmature COC analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic strategy for reproductive aged women by regulation of oxidative stress and endoprasmic reticulum stress

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To uncover the pathogenesis of preeclampsia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of aging-related decline in oocyte quality: a study of metabolomics and autophagy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of molecular mechanism of the precipitation/inhibition of uterine endometrial epithelial cell proliferation by SERMPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] クエン酸クロミフェンによる子宮内膜増殖抑制作用の分子機構.産婦人科の実際2010

Author(s)

Data Source

[Journal Article] Next-Generation Sequencing Reveals Downregulation of the Wnt Signaling Pathway in Human Dysmature Cumulus Cells as a Hallmark for Evaluating Oocyte Quality2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of syncytiotrophoblast generated from human embryonic stem cells and from term placentas.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular and molecular mechanisms of various types of oocyteaging2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bezafibrate restores the inhibition of FSH-induced follicular development and steroidogenesis by tumor necrosis factor-alpha through peroxisome proliferator-activated receptor-gamma pathway in an in vitro mouse preantral follicle culture2011

Author(s)

Journal Title

Data Source

[Journal Article] Usefulness of bezafibrate for ovulation induction in clomiphene citrate-resistant polycystic ovary syndrome patients with dyslipidemia a prospective pilot study of seven cases2010

Author(s)

Journal Title

Data Source

[Journal Article] Molecular mechanism of poor embryo development in postovulatory aged oocytes

Author(s)

Journal Title

Data Source

[Presentation] 卵丘細胞・卵子複合体(COC)の成熟度分類とタイムラプス動態解析を利用したKIDScoreとの関連性2021

Author(s)

Organizer

Data Source

[Presentation] Dysmature卵丘細胞・卵子複合体(COC)由来卵子はART成績不良と関連する2020

Author(s)

Organizer

Data Source

[Presentation] Maturity of cumulus oocyte complex (COC) predicts the outcome of ART. ~ Focus on Dysmature ~2019

Author(s)

Organizer

Data Source

[Presentation] 受精方法による卵丘細胞・卵子複合体(COC)の成熟度とART成績との関連について2019

Author(s)

Organizer

Amita Mitsuyoshi 網田光善

AMITA Mitsuyoshi 網田光善

[Presentation] 卵丘細胞・卵子複合体（COC）の成熟度はART成績を予測する指標となる～Dysmature卵子についての検討～2019