Kawasaki Yuki 河崎優希

… Alternative Names

Yuki Kawasaki 河崎優希

KAWASAKI Yuki 河崎優希

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Researcher Number	30432107
Other IDs
Affiliation (Current)	2023: 高崎健康福祉大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2021: 高崎健康福祉大学, 薬学部, 講師 2016 – 2018: 富山大学, 大学院医学薬学研究部(薬学), 助教 2011 – 2014: 富山大学, 大学院医学薬学研究部(薬学), 助教 2012: 富山大学, 大学院・医学薬学研究部(薬学), 助教 2008 – 2010: 富山大学, 大学院・医学薬学研究部(薬学), 助教 … More 2008: 富山大学, 医学薬学研究部(薬学), 助教 2008: 富山大学, 大学院・大学院医学薬学研究部(薬学), 助教 2007: 富山大学, 医学薬学研究部(薬学), 准教 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Medical pharmacy / Tumor biology
Keywords	Principal Investigator ErbB / リン酸化 / がん / CYP1A2 / 遺伝子発現制御 / 性差 / 遺伝子発現調節 / 転写因子 / チロシンキナーゼ / シグナル伝達 … More / 分子標的 / ErbBファミリー / フィードバック / セリン/スレオニン / チロシンキナーゼ型受容体 / がん分子標的薬 / 獲得耐性 / 薬学 / 受容体型チロシンキナーゼ / mTOR / 分子標的薬 / 耐性 … More Except Principal Investigator シグナル伝達 / シトクロムP450 / 性差 / マウス / 薬物代謝 / CYP2B9 / 成長ホルモン / 性ホルモン / HNF3β(FoxA2) / 薬物代謝酵素 / CYP3A / 発現制御 / 性特異性 / CYP / 発現調節 / エピジェネティック / がん / チロシンキナーゼ / リン酸化 / 小胞輸送 / EGFR / EphA2 / 受容体 / 増殖因子 / キナーゼ / 細胞 / 癌 Less

mTOR経路活性化におけるErbBフィードバック制御解明によるがん悪性化克服Principal Investigator
- Principal Investigator
  
  河崎優希
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Takasaki University of Health and Welfare
ErbB family feedback regulation via a conserved Thr phosphorylationPrincipal Investigator
- Principal Investigator
  
  Kawasaki Yuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Takasaki University of Health and Welfare
  University of Toyama
Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression
- Principal Investigator
  
  Hiroaki Sakurai
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  University of Toyama
Role of epigenetic regulation on female-predominant expression of drug-metabolizing enzyme CYP3A gene
- Principal Investigator
  
  SAKUMA TSUTOMU
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
Molecular mechanism of CYP1A2 gene expression in male regulated bygrowth hormone for personalized medicinePrincipal Investigator
- Principal Investigator
  
  KAWASAKI Yuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
Mechanisms of female-specific expression of drug-metabolizing enzyme CYP3A : comparison between human and mouse
- Principal Investigator
  
  SAKUMA Tsutomu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
Sex-dependent expression mechanism of cytochrome P450 by growth hormone and a transcription factor, HNF3β or HNF4α
- Principal Investigator
  
  NEMOTO Nobuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama

All 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation.2019
- Author(s)
  Haryuni Ratna Dini、Watabe Satoko、Yamaguchi Asako、Fukushi Yayoi、Tanaka Tomohiro、Kawasaki Yuki、Zhou Yue、Yokoyama Satoru、Sakurai Hiroaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 514 Pages: 456-461
- DOI
  10.1016/j.bbrc.2019.04.125
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07227, KAKENHI-PROJECT-16K08366
[Journal Article] Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation2019
- Author(s)
  Haryuni R.D., Watabe S., Yamaguchi A., Fukushi Y., Tanaka T., Kawasaki Y., Zhou Y., Yokoyama S., and Sakurai H.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04694
[Journal Article] Two different mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via ERK and p38 pathways2017
- Author(s)
  Park C.M., Kawasaki Y., Refaat A. and Sakurai H.
- Journal Title
  
  Oncology Letters
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08366
[Journal Article] Two different mechanisms for chemotherapeutic agent-induced inactivation of ErbB2 and ErbB3 via ERK and p38 pathways in breast cancer cells.2017
- Author(s)
  Park C.M., Kawasaki Y., Refaat A., and Sakurai H.
- Journal Title
  
  Oncology Letters
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H04694
[Journal Article] Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain.2016
- Author(s)
  Kawasaki Y, Sakimura A, Park CM, Tomaru R, Tanaka T, Ozawa T, Zhou Y, Narita K, Kishi H, Muraguchi A, Sakurai H
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 31502-31502
- DOI
  10.1038/srep31502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-16H04694, KAKENHI-PROJECT-15K09522, KAKENHI-PROJECT-16K08366
[Journal Article] p38-mediated phosphorylation of Eps15 endocytic adaptor protein2014
- Author(s)
  Zhou Y., Tanaka T., Sugiyama N., Yokoyama S., Kawasaki Y., Sakuma T., Ishihama Y., Saiki I., and Sakurai H.
- Journal Title
  
  FEBS Lett
  
  Volume: 588 Pages: 131-137
- DOI
  10.1016/j.febslet.2013.11.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590071, KAKENHI-PROJECT-23590172, KAKENHI-PUBLICLY-24116513, KAKENHI-PROJECT-24241062, KAKENHI-PROJECT-24659017, KAKENHI-PROJECT-24659348, KAKENHI-PROJECT-24700971
[Journal Article] Modified expression of aryl hydrocarbon receptor-related genes by deoxymiroestrol, a phytoestrogen, in mouse hepatocytes in primary culture2011
- Author(s)
  Udomsuk L., Jarukamjorn K., Putalun W., Sakuma T., Kawasaki Y., Nemoto N
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 137 Pages: 902-908
- DOI
  10.1016/j.jep.2011.06.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590172
[Journal Article] Udomsuk L., Jarukamjorn K., PutalunW., Sakuma T., Kawasaki Y., Nemoto N.2011
- Author(s)
  Udomsuk L., Jarukamjorn K., PutalunW., Sakuma T., Kawasaki Y., Nemoto N.
- Journal Title
  
  J. Ethnopharmacol.
  
  Volume: 137 Pages: 902-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790177
[Journal Article] Modified expression of aryl hydrocarbon receptor-related genes by deoxymiroestrol, a phytoestrogen, in mouse hepatocytes in primary culture.2011
- Author(s)
  Latiporn Udomsuk, Kanokwan Jarukamjorn, Waraporn Putalun, Tsutomu Sakuma, Yuki Kawasaki and Nobuo Nemoto.
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 137 Pages: 902-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790177
[Journal Article] Hepatocyte nuclear factor 4 alpha regulates expression of the mouse female-specific Cyp3a41 gene in the liver2011
- Author(s)
  Bhadhprasit W., Sakuma T., Kawasaki Y., Nemoto N
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 39 Pages: 490-497
- DOI
  10.1124/dmd.110.035980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590172
[Journal Article] Hepatocyte nuclear factor 4 alpha regulates expression of the mouse female-specific Cyp3a41 gene in the liver.2011
- Author(s)
  Bhadhprasit W., Sakuma T., Kawasaki Y., Nemoto N.
- Journal Title
  
  Drug Metab. Dispos. 39
  
  Pages: 490-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590140
[Journal Article] Regulatory xenobiotic responsive elements in the distal 5'-flanking region of the mouse Cypla2 gene required for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.2010
- Author(s)
  Kawasaki Y., Sakuma T., Goto Y., Nemoto N.
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 1640-1643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590140
[Journal Article] Potent modification of inducible CYP1A1 expression by flavonoids.2010
- Author(s)
  Chatuphonprasert W., Kondo S., Jarukamjorn K., Kawasaki Y., Sakuma T., Nemoto N.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 1698-1703
- NAID
  130000402364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590140
[Journal Article] Gender-associated modulation of inducible CYP1A1 expression by andrographolide in mouse liver.2010
- Author(s)
  Jarukamjorn K., Kondo S., Chatuphonprasert W., Sakuma T., Kawasaki Y., Nemoto N.
- Journal Title
  
  Eur.J.Pharm.Sci. 39
  
  Pages: 394-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590140
[Journal Article] Alteration of acetaminophen-induced cytotoxicity in mouse hepatocytes during primary culture.2009
- Author(s)
  Jaruchotikamol A, Takase A, Ito S, Kawasaki Y., Kondo S, Sakuma T., Nemoto N.
- Journal Title
  
  J.Health Sci. 55
  
  Pages: 767-776
- NAID
  130000127965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590140
[Journal Article] Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes2008
- Author(s)
  Jaruchotikamol A., Jarukamjorn K, Sirisangtrakul W, Sakuma T, Kawasaki Y, and Nemoto N
- Journal Title
  
  Toxicol. Appl. Pharmacol 224
  
  Pages: 156-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590140
[Journal Article] Strong synergistic induction of CYP1A1 expression by androgra-pholide plus typical CYP1A inducers in mouse hepatocytes2007
- Author(s)
  Jaruchotikamol A., Jarukamjorn K., Sirisangtrakul W., Sakuma T., Kawasaki Y., Nemoto N.
- Journal Title
  
  Toxicol. Appl. Pharmacol 224
  
  Pages: 156-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590140
[Presentation] ErbB2/3ヘテロダイマーにおける新たな非定型的リン酸化部位の同定2019
- Author(s)
  地子愛佳理, 池ヶ谷真吾, 馬場絢子, 河崎優希, 周越, 櫻井宏明
- Organizer
  日本薬学会北陸支部第131回例会
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ErbB2/ErbB3ヘテロ二量体におけるERK経路を介した新規ErbB2リン酸化部位の探索2018
- Author(s)
  河崎優希, 池ヶ谷真吾, 馬場絢子, 地子愛佳理, 櫻井宏明
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] Negative feedback regulation of ErbB4 receptor tyrosine kinase by non-canonical phosphorylation at threonine-674 and serine-10262018
- Author(s)
  Haryuni RD., Watabe S., Yamaguchi A., Fukushi Y., Kawasaki Y., Sakurai H.
- Organizer
  The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ErbB2/ErbB3ヘテロ二量体におけるERKを介した新規ErbB2リン酸化部位の探索2018
- Author(s)
  河崎優希, 池ヶ谷真吾, 馬場絢子, 地子愛佳理, 櫻井宏明
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] ErbB2/ErbB3ヘテロダイマーのMAPKを介したリン酸化制御機構の解明2018
- Author(s)
  池ヶ谷真吾、馬場絢子、河崎優希、櫻井宏明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ERK-mediated feedback regulation of ErbB family via the conserved Thr phosphorylation2018
- Author(s)
  Kawasaki Y., Sakurai H.
- Organizer
  The Third International Symposium on Toyama-Asia-Africa Pharmaceutical Network
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] がん細胞におけるErbBファミリーの膜近傍領域スレオニンリン酸化による活性調節機構2017
- Author(s)
  河崎優希, 櫻井宏明
- Organizer
  フォーラム2017 衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] がん細胞におけるErbBファミリーの膜近傍領域スレオニンリン酸化による活性調節機構2017
- Author(s)
  河崎優希、櫻井宏明
- Organizer
  フォーラム2017 衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] Negative feedback control of ErbB4 by tyrosine kinase independent non-canonical phosphorylation2017
- Author(s)
  山口麻子、渡部聡子、福司弥生、田中智大、河崎優希、櫻井宏明
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] チロシン脱リン酸化酵素を介した受容体型チロシンキナーゼErbBファミリーフィードバックの制御2017
- Author(s)
  河崎優希, 櫻井宏明
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] チロシン脱リン酸化酵素を介した受容体型チロシンキナーゼErbBファミリーフィードバックの制御2017
- Author(s)
  河崎優希、櫻井宏明
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] チロシンキナーゼ非依存的なリン酸化によるErbB4のフィードバック阻害機構2017
- Author(s)
  山口麻子，渡部聡子，福司弥生，田中智大，河崎優希，櫻井宏明
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] ErbB2/ErbB3ヘテロ二量体におけるERKを介したErbB2 Thr-677リン酸化によるフィードバック制御.2016
- Author(s)
  河崎優希, 﨑村綾香, 朴哲珉, 周越, 都丸里佳, 成田香織, 小澤龍彦, 村口篤, 櫻井宏明.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] チロシンキナーゼ非依存的なErbB4リン酸化の役割．2016
- Author(s)
  渡部聡子，山口麻子，福司弥生，田中智大，河崎優希，櫻井宏明．
- Organizer
  第76回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] ErbB2/ErbB3ヘテロ二量体におけるERKを介したErbB2 Thr-677リン酸化によるフィードバック制御2016
- Author(s)
  河崎優希、﨑村綾香、朴哲珉、周越、都丸里佳、成田香織、小澤龍彦、村口篤、櫻井宏明
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ErbB2/Erb3ヘテロダイマーのMAPKを介したリン酸化制御機構の解明2016
- Author(s)
  馬場絢子、池ヶ谷真吾、河崎優希、櫻井宏明
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  北陸大学、金沢市
- Year and Date
  2016-11-27
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] Down-regulation of ErbB2/ErbB3 heterodimer via ERK-mediated phosphorylation of ErbB2 Thr-677 in the juxtamembrane domain2016
- Author(s)
  Yuki Kawasaki and Hiroaki Sakurai
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  Kindai University, Osaka, JAPAN
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] Roles of tyrosine kinase-independent phosphorylation of ErbB42016
- Author(s)
  渡部聡子、山口麻子、福司弥生、田中智大、河崎優希、櫻井宏明
- Organizer
  第7５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ERKを介したErbB2非定型的リン酸化によるフィードバック阻害機構2016
- Author(s)
  櫻井宏明、河崎優希
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府国際コンベンションセンター、別府市
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16K08366
[Presentation] ERKを介したErbB2非定型的リン酸化によるフィードバック阻害機構．2016
- Author(s)
  櫻井宏明，河崎優希．
- Organizer
  第20回日本がん分子標的治療学会学術集会
- Place of Presentation
  別府
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16H04694
[Presentation] マウスCyp1a2遺伝子のフェノバルビタール型誘導剤による発現調節機構の解析2014
- Author(s)
  佐久間勉、河崎優希、古野幸美、後藤雄真、茂木優治、根本信雄、櫻井宏明
- Organizer
  日本薬学会北陸支部第126回例会
- Place of Presentation
  石川県金沢市
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] 高度に保存されたスレオニンのリン酸化を介したPPARの活性調節機構2013
- Author(s)
  谷翔太，佐久間勉，手賀悠真，進藤佐和子，根岸正彦，梅嵜雅人，河崎優希，根本信雄，櫻井宏明
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] 高度に保存されているDBD内スレオニンのリン酸化による核内受容体の活性調節2013
- Author(s)
  佐久間勉，谷翔太，手賀悠真，進藤佐和子，根岸正彦，河崎優希，根本信雄，櫻井宏明
- Organizer
  フォーラム2013衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] Constitutive androstane receptor リガンド誘導性発現調節を担うマウスCyp1a2 遺伝子の5'-上流域2013
- Author(s)
  河崎優希, 古野幸美, 後藤雄真, 佐久間勉, 櫻井宏明,根本信雄
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] 成長ホルモンおよびグルココルチコイドホルモンによるマウスCyp3a遺伝子発現の比較解析2012
- Author(s)
  佐久間勉，栗本夕夏，松井友理恵，池松怜美，宅間祐太朗，河崎優希，根本信雄，櫻井宏明
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] Constitutive androstane receptor アクチベーターによる誘導性発現調節を担うマウスCyp1a2遺伝子5'-上流域2012
- Author(s)
  古野幸美, 河崎優希, 後藤雄真, 佐久間勉, 櫻井宏明, 根本信雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] Constitutive androstane receptor アクチベーターによる誘導性発現調節を担うマウスCyp1a2遺伝子5’-上流域2012
- Author(s)
  古野幸美、河崎優希、後藤雄真、佐久間勉、櫻井宏明、根本信雄
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] Regulatory Elements for Transcriptional Activation of the mouse Cyp1a2 gene by Constitutive Androstane Receptor-Ligand2012
- Author(s)
  Kawasaki Y., Furuno Y., Goto Y., Sakuma T., Sakurai H., Nemoto N.
- Organizer
  50th Anniversary Symposium on Cytochrome P450 in Fukuoka
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] Regulatory elements for transcriptional activation of the mouse Cyp1a2 gene by constitutive androstane receptor-ligand2012
- Author(s)
  Kawasaki Y., Furuno Y., Goto Y., Sakuma T., Sakurai H., and Nemoto N.
- Organizer
  50TH Anniversary Symposium on Cytochrome P450 in Fukuoka
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] PERIODIC FLUCTUATION OF CYP3A GENE EXPRESSION IN THE MOUSE LIVER2011
- Author(s)
  Tsutomu Sakuma, Satomi Ikematsu, Yuka Kurimoto, Yuki Kawasaki and Nobuo Nemoto
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] マウス全CYP3A分子種のmRNA発現量の比較解析2011
- Author(s)
  栗本夕夏, 佐久間勉, 宅間祐太郎, 池松怜美, 河崎優希, 櫻井宏明, 根本信雄
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] Constitutive androstane receptor responsive region in the 5'-flanking region of the mouse Cyp1a2 gene2011
- Author(s)
  Kawasaki Y., Goto Y., Furuno Y., Sakuma T., Sakurai H., Nemoto N
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] Periodic fluctuation of Cyp3a gene expression in the mouse liver2011
- Author(s)
  Tsutomu Sakuma, Satomi Ikematsu, Yuka Kurimoto, Yuki Kawasaki, Nobuo Nemoto
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23590172
[Presentation] Constitutive androstane receptor responsive region in the 5’-flanking region of the mouse Cyp1a2 gene2011
- Author(s)
  Yuki Kawasaki, Yuma Goto, Akira Honryo, Yukimi Furuno, Tsutomu Sakuma, Nobuo Nemoto
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] マウスCyp3a41遺伝子構造とHNF4αによる性特異的発現2010
- Author(s)
  佐久間勉, 池松怜美, Bhadhprasit Wattanaporn, 河崎優希, 根本信雄
- Organizer
  日本薬学会北陸支部第122回例会
- Place of Presentation
  金沢
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] Regulatory XREs in distal 5'-flanking region of the mouse Cypla2 gene for transcriptional activation by 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.2010
- Author(s)
  Kawasaki Y., Yuma Goto, Sakuma T., Nemoto N.
- Organizer
  18th International Symposium on Microsomes and Drug Oxidations
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] Role of hepatocyte nuclear factor 4 alpha and chromatin structure in the regulation of female-specific Cyp3a41 gene expression.2010
- Author(s)
  Sakuma T., Bhadhprasit W., Kawasaki Y., Nemoto N.
- Organizer
  18th International Symposium on Microsomes and Drug Oxidations
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] Cyp3a41遺伝子メス特異的発現の調節機構2010
- Author(s)
  佐久間勉, Bhadhprasit Wattanaporn, 河崎優希, 近藤佐千子, 根本信雄
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] メスマウス肝でのCyp3a41遺伝子発現におけるクロマチン構造とHNF4αの役割2010
- Author(s)
  佐久間勉, 池松怜美, Bhadhprasit Wattanaporn, 河崎優希, 近藤佐千子, 根本信雄
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] グルココルチコイドによるCyp3a41遺伝子の発現調節機構:Glucocoeticoid receptorおよびHepatocyte nuclear factor-4αの役割2009
- Author(s)
  Bhadhprasit Wattanaporn, 佐久間勉, 河崎優希, 根本信雄
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590140
[Presentation] 12のXを含むCyp1a2遺伝子の5'上流域による3-MC並びに2,3,7,8-TCDD誘導性マウスCyp1a2遺伝子転写調節2009
- Author(s)
  河崎優希, 佐久間勉, 根本信雄
- Organizer
  第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590140
[Presentation] Cypla2遺伝子5'上流域による3-メチルコラントレン並びに2, 3, 7, 8-TCDD誘導性マウスCypla2遺伝子転写調節2008
- Author(s)
  河崎優希, 佐久間勉, 根本信雄
- Organizer
  第23回日本薬物動態学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19590140
[Presentation] 12のXREを含むCypla2遺伝子の5'上流域による3-MC並びに2, 3, 7, 8-TCDD誘導性マウスCypla2遺伝子転写調節.2008
- Author(s)
  河崎優希, 佐久間勉, 根本信雄
- Organizer
  第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590140
[Presentation] Trp-P-1の肝毒性に対するepigallocatechin gallate (EGCG)の抑制効果.2007
- Author(s)
  亀井美穂, Jaruchotikamol A., 河崎優希, 根本信雄
- Organizer
  日本薬学会北陸支部第117回例会
- Place of Presentation
  金沢
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19590140
[Presentation] Constitutive androstane receptor リガンド誘導性発現調節を担うマウスCyp1a2遺伝子の5’-上流域
- Author(s)
  河崎優希、古野幸美、後藤雄真、佐久間勉、櫻井宏明、根本信雄
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] Regulatory Elements for Transcriptional Activation of the mouse Cyp1a2 gene by Constitutive Androstane Receptor-Ligand
- Author(s)
  Yuki Kawasaki, Yukimi Furuno, Yuma Goto, Tsutomu Sakuma, Hiroaki Sakurai and Nobuo Nemoto
- Organizer
  50th Anniversary Symposium on Cytochrome P450 in Fukuoka
- Place of Presentation
  九州大学（福岡市）
- Data Source
  KAKENHI-PROJECT-23790177
[Presentation] マウスCyp1a2遺伝子フェノバルビタール型誘導剤応答領域の解析
- Author(s)
  佐久間勉、河崎優希、古野幸美、後藤雄真、茂木優治、根本信雄、櫻井宏明
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23590172

1. SAKUMA Tsutomu (30250468)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
2. NEMOTO Nobuo (10085631)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. Hiroaki Sakurai (00345571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 小澤龍彦 (10432105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. ISHIHAMA YASUSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. SUGIYAMA Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 横山悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 済木育夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岸裕幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawasaki Yuki 河崎 優希

Yuki Kawasaki 河崎 優希

KAWASAKI Yuki 河崎 優希

Research Projects

Research Products

Co-Researchers

mTOR経路活性化におけるErbBフィードバック制御解明によるがん悪性化克服Principal Investigator

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ErbB family feedback regulation via a conserved Thr phosphorylationPrincipal Investigator

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Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression

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Role of epigenetic regulation on female-predominant expression of drug-metabolizing enzyme CYP3A gene

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Molecular mechanism of CYP1A2 gene expression in male regulated bygrowth hormone for personalized medicinePrincipal Investigator

Principal Investigator

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Mechanisms of female-specific expression of drug-metabolizing enzyme CYP3A : comparison between human and mouse

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Sex-dependent expression mechanism of cytochrome P450 by growth hormone and a transcription factor, HNF3β or HNF4α

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[Journal Article] Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation.2019

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[Journal Article] Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation2019

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[Journal Article] Two different mechanisms for DNA-damaging agent-induced inactivation of ErbB2 and ErbB3 via ERK and p38 pathways2017

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[Journal Article] Two different mechanisms for chemotherapeutic agent-induced inactivation of ErbB2 and ErbB3 via ERK and p38 pathways in breast cancer cells.2017

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[Journal Article] Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain.2016

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[Journal Article] p38-mediated phosphorylation of Eps15 endocytic adaptor protein2014

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[Journal Article] Modified expression of aryl hydrocarbon receptor-related genes by deoxymiroestrol, a phytoestrogen, in mouse hepatocytes in primary culture2011

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Kawasaki Yuki 河崎優希

Yuki Kawasaki 河崎優希

KAWASAKI Yuki 河崎優希