Kanno Keishi 菅野啓司

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KANNO Keishi 菅野啓司

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Researcher Number	30448237
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(医), 准教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 広島大学, 病院(医), 准教授 2013: 広島大学, 大学病院, 講師 2013: 広島大学, 病院, 助教 2012: 広島大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Studies on the Super-Aging Society
Keywords	Principal Investigator 核酸医療 / 肝脂質代謝 / アポトーシス / 細胞外マトリックス蛋白 / 肝脂肪化 / 肝星細胞 / 非アルコール性脂肪性肝炎 / ペリオスチン / 脂肪肝 / 肝線維化 / 非アルコール性脂肪肝炎 / 非アルコール性脂肪性肝疾患 / アンチセンス核酸 … More Except Principal Investigator … More 外耳道センサ / 極泉・壇中・翳風センサ / 情動と痛みのデジタル化 / IoTウエアラブルデバイス / ブレインセンシング / 認知症 / ブレインセンシング技術 / 多職種協働 / プライマリ・ケア / 地域包括ケアシステム / ICT / 地域医療 / Society 5.0 / IoTデバイス / 在宅看取り / オンライン診療 / ビッグデータ / IoHウエアラブルデバイス / 看取り / ウェルビーイング / 胆道がん / 硬化性胆管炎 / 腫瘍性コランギオパチー / 劣化脂質 / 胆管 / コランギオパチー / アポトーシス / ＥＭＴ / ペリオスチン / EMT / 変性脂質 / モノクロナル抗体 / 筋線維芽細胞 / 阻害抗体 / 肺線維化 / 肝線維化 / 肝硬変 / 抗体医薬 / TGF-β / 星細胞 / 線維症 / インテグリン Less

Study of emotion and the pain to be able to put to nurse you at home using the brain sensing technology.
- Principal Investigator
  
  中村浩士
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Pharmaceutical applications of periostin antisenseoligo for non-alcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  Kanno Keishi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hiroshima University
Pathogenesis and management of carcinogenic cholangiopathy induce by deteriorated lipids
- Principal Investigator
  
  Tazuma Susumu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University
Activated hepatic stellate cell specific antibody that attenuates liver fibrosis: mechanism of action and therapeutic use
- Principal Investigator
  
  YOKOSAKI Yasuyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Hiroshima University

All 2020 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Other

[Journal Article] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of nonalcoholic steatohepatitis2020
- Author(s)
  Kobayashi T, Kanno K, Nguyen PT, Sugiyama A, Kawahara A, Otani Y, Kishikawa N, Ito M, Tazuma S
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 35 Issue: 12 Pages: 2140-2150
- DOI
  10.1111/jgh.15088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07940
[Journal Article] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma2017
- Author(s)
  Mino M, Kanno K, Okimoto K, Sugiyama A, Kishikawa N, Kobayashi T, Ono J, Izuhara K, Kobayashi T, Ohigashi T, Ohdan H, Tazuma S
- Journal Title
  
  Hepatol Commun
  
  Volume: 1 Issue: 10 Pages: 1099-1109
- DOI
  10.1002/hep4.1114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05343, KAKENHI-PROJECT-15K10166, KAKENHI-PROJECT-15K15372, KAKENHI-PROJECT-16K09396
[Journal Article] Ursodeoxycholic acid after bile duct stone removal and risk factors2016
- Author(s)
  Yamamoto R, Tazuma S, Kanno K, Igarashi Y, Inui K, Ohara H, Tsuyuguchi T,
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 23 Issue: 2 Pages: 132-136
- DOI
  10.1002/jhbp.316
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09396
[Journal Article] Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a　choline-deficient diet: a follow-up report on long-term effects of oxidative2016
- Author(s)
  Yamamoto H, Kanno K, Ikuta T, Arihiro K, Sugiyama A, Kishikawa N, Tazuma S.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 23 Issue: 5 Pages: 260-269
- DOI
  10.1002/jhbp.333
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09396
[Journal Article] Periostin promotes hepatic fibrosis in mice by modulating2016
- Author(s)
  Sugiyama A, Kanno K, Nishimichi N, Ohta S, Ono J, Conway SJ, Izuhara K,
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51 Pages: 1161-1174
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Journal Article] Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does2016
- Author(s)
  Kishikawa N, Kanno K, Sugiyama A, Yokobayashi K, Mizooka M, Tazuma S.
- Journal Title
  
  J Hepatobiliary Pancreat Sci.
  
  Volume: 23 Issue: 2 Pages: 125-131
- DOI
  10.1002/jhbp.313
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] 肝線維化に対する新たな治療戦略-ペリオスチンに対するアンチセンス核酸製剤の有用性2019
- Author(s)
  小林知貴、菅野啓司、田妻進
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07940
[Presentation] dca species decreased largely in hepatic bile acid compositions of NAFLD animal model with hypertension2018
- Author(s)
  Kodama M, Tazuma S, Kanno K
- Organizer
  69th Annual Meeting, American Association for the Study of Liver Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment2018
- Author(s)
  Kobayashi M, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S
- Organizer
  9th Annual Meeting, American Association for the Study of Liver Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment.2018
- Author(s)
  Kobayashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S
- Organizer
  69th Annual Meeting, American Association for the Study of Liver Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07940
[Presentation] Altered Bile Acid Synthesis Pathway in Hypertentionassociated Non-Alcoholic Steatohepatitis Animal Model.2017
- Author(s)
  Kodama M, Kanno K, Tazuma S.
- Organizer
  The 118th AGA meeting (May 6-9, 2017, Chicago, Illinois)
- Place of Presentation
  Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.2017
- Author(s)
  Sugiyama A, Mino M, Kanno K, Ono J, Kishikawa N, Kobayashi T, Kobayashi T, Ohdan H, Tazuma S.
- Organizer
  The 118th AGA meeting (May 6-9, 2017, Chicago, Illinois)
- Place of Presentation
  Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] An essential role of hepatic cholesterol and bile acid metabolism mediated by nuclear receptors in the development of hypertension-associated non-alcoholic steatohepatitis.2016
- Author(s)
  Kodama M, Tazuma S, Kanno K.
- Organizer
  Asian Pacific Digestive Week 2016
- Place of Presentation
  Kobe, Japan
- Year and Date
  2016-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09396
[Presentation] Inhibition Of Pulmonary Fibrosis By Integrin α8β1 Blocking Antibody and TGFβ-Independent Myofibroblast Differentiation By α8β1 Mediated Signal2014
- Author(s)
  Y. Yokosaki, N. Nishimichi, K. Kanno, K. Sentani
- Organizer
  American Thoracic Society 2014 International Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] Myofibroblast Differentiation Mediated By Integrin α8β1.2014
- Author(s)
  Norihisa Nishimichi, Keishi Kanno, Akiko Sugiyama, Yasuyuki Yokosaki
- Organizer
  Keystone Symposia
- Place of Presentation
  Keystone, CO, USA
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] 新しい肺線維化抑制薬シーズインテグリンα8β1阻害抗体2014
- Author(s)
  横崎恭之、西道教尚、仙谷和弘、菅野啓司、安井弥
- Organizer
  第54日本呼吸器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] A possible therapeutic agent for pulmonary fibrosis: antibody against integrin α8β1.2013
- Author(s)
  Yokosaki Y, Nishimichi N, Kanno K, Senatani K, Yasui W.
- Organizer
  European Respiratory Society
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] A possible therapeutic agent for pulmonary fibrosis : antibody against integrinα8β12013
- Author(s)
  Yokosaki Y, Nishimichi N, Kanno K, Senatani K, Yasui W.
- Organizer
  European Respiratory Society
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] Integrinα8β1 as a new therapeutic target for tissue fibrosis. American Thoracic Society2012
- Author(s)
  Norihisa Nishimichi, Keishi Kanno, Neil C. Henderson, Dean Sheppard, Yasuyuki Yokosaki
- Organizer
  2012 International Meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] インテグリンα8β1 は活性化肝星細胞に発現し肝線維化を促進する2012
- Author(s)
  西道教尚、菅野啓司、仙谷和弘、安井弥、横崎恭之
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] Integrin α8β1 As A New Therapeutic Target For Tissue Fibrosis2012
- Author(s)
  Norihisa Nishimichi, Keishi Kanno, Neil C. Henderson, Dean Sheppard, Yasuyuki Yokosaki
- Organizer
  American Thoracic Society, 2012 International Meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24659367
[Presentation] インテグリンα8β1は活性化肝星細胞に発現し肝線維化を促進する2012
- Author(s)
  西道教尚、菅野啓司、仙谷和弘、安井弥、横崎恭之
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24659367
[]

1. Tazuma Susumu (80201614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. 小林知貴 (00817075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 岸川暢介 (50711347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. YOKOSAKI Yasuyuki (80210607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. SENTANI Kazuhiro (30508164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. NISHIMICHI Norihisa (00583486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 大谷裕一郎 (00817091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 杉山晶子 (30788469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 中村浩士 (00380006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 梅本誠治 (90263772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 池田栄二 (30232177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中島翔太 (20580963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 平野旭 (60594778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 加澤佳奈 (10740102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 神田隆 (40204797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 川井元晴 (60294641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松田守弘 (00362591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 越久仁敬 (20252512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 出原賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanno Keishi 菅野 啓司

KANNO Keishi 菅野 啓司

Research Projects

Research Products

Co-Researchers

Study of emotion and the pain to be able to put to nurse you at home using the brain sensing technology.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmaceutical applications of periostin antisenseoligo for non-alcoholic fatty liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis and management of carcinogenic cholangiopathy induce by deteriorated lipids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activated hepatic stellate cell specific antibody that attenuates liver fibrosis: mechanism of action and therapeutic use

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of nonalcoholic steatohepatitis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ursodeoxycholic acid after bile duct stone removal and risk factors2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a choline-deficient diet: a follow-up report on long-term effects of oxidative2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Periostin promotes hepatic fibrosis in mice by modulating2016

Author(s)

Journal Title

Data Source

[Journal Article] Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肝線維化に対する新たな治療戦略-ペリオスチンに対するアンチセンス核酸製剤の有用性2019

Author(s)

Organizer

Data Source

[Presentation] dca species decreased largely in hepatic bile acid composi&shy;tions of NAFLD animal model with hyperten&shy;sion2018

Author(s)

Organizer

Data Source

[Presentation] Periostin antisense oligonucleotide prevents hepatic ste&shy;atosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment2018

Author(s)

Organizer

Data Source

[Presentation] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment.2018

Author(s)

Organizer

Data Source

[Presentation] Altered Bile Acid Synthesis Pathway in Hypertentionassociated Non-Alcoholic Steatohepatitis Animal Model.2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.2017

Kanno Keishi 菅野啓司

KANNO Keishi 菅野啓司

[Journal Article] Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a　choline-deficient diet: a follow-up report on long-term effects of oxidative2016

[Presentation] dca species decreased largely in hepatic bile acid compositions of NAFLD animal model with hypertension2018

[Presentation] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment2018