MINAMIZAKI Tomoko 南崎朋子

Researcher Number	30452593
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2021: 広島大学, 医系科学研究科(歯), 助教 2018: 広島大学, 医歯薬保健学研究科, 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 助教 2016: 広島大学, 医歯薬保健学研究院(歯), 助教 2012 – 2015: 広島大学, 医歯薬保健学研究院, 助教 … More 2012: 広島大学, 大学院・医歯薬保健学研究院, 助教 2011: 広島大学, 医歯(薬)学総合研究科, 助教 2010: 広島大学, 医歯薬学総合研究科, 助教 2008 – 2010: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2007: Hiroshima University, 大学院・医歯薬学総合研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Orthodontic/Pediatric dentistry / Basic Section 57010:Oral biological science-related Except Principal Investigator Morphological basic dentistry / Basic Section 57010:Oral biological science-related
Keywords	Principal Investigator 骨代謝 / 細胞・組織 / リン代謝 / FGF23 / 骨芽細胞 / 骨転移 / 石灰化 / Klotho / miRNA / 歯学 … More / シグナル伝達 / 骨形成 / 歯の形成 / 無機リン酸 / リン酸代謝調節 / 低リン血症 / カルシウム代謝 / 再生医学 / PTH / がん細胞 / 骨吸収 / miR-125b / 基質小胞 … More Except Principal Investigator 骨芽細胞 / GF23 / Klotho / 石灰化 / マップキナーゼ(ERK) / FGF23 / 可溶型Klotho / 可溶化Klotho(細胞外ドメイン) / 歯・骨の石灰化 / マウス / KLotho / ERK / 血管異所性石灰化 / 血管平滑筋 / RNAシーケンシング / イノシトールリン酸 / 異所性石灰化 / 次世代シークエンシング Less

クロマチンと遺伝子発現の網羅的解析の併用による組織特異的石灰化機序の同定
- Principal Investigator
  
  河野尚平
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hiroshima University
miR-125bを導入した基質小胞による癌骨転移治療の検討Principal Investigator
- Principal Investigator
  
  南崎朋子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hiroshima University
A trial of miRNAs derived from bone matrix as an inhibitor for bone metastasisPrincipal Investigator
- Principal Investigator
  
  Minamizaki Tomoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
The roles of downstream factor(s) of cancer cell-derived Klotho on bone mineralizationPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI TOMOKO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study of de novo function of PTH in mineral metabolism disordersPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI Tomoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study of Klotho as a local factor of hard tissue reproductionPrincipal Investigator
- Principal Investigator
  
  MINAMIZAKI Tomoko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
A basic study on FGF23 for molecular targeted therapy of bone/tooth diseases
- Principal Investigator
  
  YOSHIKO Yuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Hiroshima University
局所リン酸代謝調節に基づく新規の骨・歯科疾患治療の基礎的研究Principal Investigator
- Principal Investigator
  
  南崎朋子
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Hiroshima University

All 2021 2018 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] The bioactive acidic serine- and aspartate-rich motif peptide.2015
- Author(s)
  Minamizaki T, Yoshiko Y.
- Journal Title
  
  Current Protein & Peptide Science
  
  Volume: 16 Pages: 196-202
- DOI
  10.2174/1389203716666150206122839
- NAID
  120006879596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462858
[Journal Article] Functional Diversity of Fibroblast Growth Factors in Bone　Formation.2015
- Author(s)
  Takei Y, Minamizaki T, Yoshiko Y.
- Journal Title
  
  International journal of endocrinology
  
  Volume: 2015 Pages: 729352-729352
- DOI
  10.1155/2015/729352
- NAID
  120006824054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462858, KAKENHI-PROJECT-26861548
[Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012
- Author(s)
  Yoshioka Hirotaka, Yoshiko Yuji, Minamizaki Tomoko, Suzuki Sayaka, Koma Yoshiro, Nobukiyo Asako, Sotomaru Yusuke, Suzuki Atsushi, Ito Mitsuyasu, Maeda Norihiko
- Journal Title
  
  Calcif Tissue Int
  
  Volume: 89 Pages: 192-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792105
[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures.2012
- Author(s)
  Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, KOzai Katsuyuki, Aubin Jane E, Maeda Norihiko
- Journal Title
  
  Prostaglandins Other Lipid Mediat.
  
  Volume: 97 Pages: 97-102
- DOI
  10.1016/j.prostaglandins.2012.01.001
- NAID
  120006879597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012
- Author(s)
  Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E Aubin, Maeda Norihiko
- Journal Title
  
  Prostaglandins Other Lipid Mediat
  
  Volume: 97 Pages: 97-102
- NAID
  120006879597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792105
[Journal Article] Incisor snemal formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012
- Author(s)
  Hirotaka Yoshioka, Yuji Yoshiko, Tomoko Minamizaki, Sayaka Suzuki, Yoshiro Koma, Asako Nobukiyo, Yusuke Sotomaru, Atsushi Suzuki, Mitsuyasu Itoh, Norihiko Maeda
- Journal Title
  
  Calcif Tissue Int.
  
  Volume: 89 Pages: 192-202
- DOI
  10.1007/s00223-011-9506-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791768, KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
[Journal Article] 1・,25-dihydroxy-vitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010
- Author(s)
  Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, et al.
- Journal Title
  
  J Endocrinol 206(3)
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010
- Author(s)
  Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, et al.
- Journal Title
  
  PLoS One 26 5(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010
- Author(s)
  Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, Tanne K, Maeda N, Aubin JE.
- Journal Title
  
  PLoS One 26, 5(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] 1α,25-dihydroxyvitamin D_3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010
- Author(s)
  Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, Tanne K, Aubin JE, Maeda N.
- Journal Title
  
  J Endocrinol 206(3)
  
  Pages: 279-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N.
- Journal Title
  
  Bone 44(6)
  
  Pages: 1177-1185
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791788
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E_2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Tomoko Minamizaki
- Journal Title
  
  Bone (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890140
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N
- Journal Title
  
  Bone 44(6)
  
  Pages: 1177-1185
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009
- Author(s)
  Tomoko Minamizaki
- Journal Title
  
  Bone (In press)
- NAID
  120001924001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] New Insights into the Roles of Fibroblast Growth Factor 23.2008
- Author(s)
  Yoshiko Y, Minamizaki T, Maeda N
- Journal Title
  
  Clinzc Rev Bone Miner Metab 6
  
  Pages: 17-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592139
[Journal Article] 低リン血症にみる歯の形成の分子基盤2008
- Author(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 鈴木清香, 前田憲彦
- Journal Title
  
  広島歯誌 36
  
  Pages: 1-12
- Data Source
  KAKENHI-PROJECT-20592139
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2011
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 前田憲彦, 香西克之, 渡邉和晃
- Industrial Property Rights Holder
  国立大学法人広島大学, 株式会社ラフィーネインターナショナル
- Industrial Property Number
  2011-123853
- Filing Date
  2011-06-01
- Data Source
  KAKENHI-PROJECT-23792105
[Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤、抗体ならびに硬組織および/または異所性石灰化促進剤2011
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 平田伊佐雄, 香西克之, 前田憲彦, 渡邉和晃, 清藤勉
- Industrial Property Rights Holder
  国立大学法人広島大学, 株式会社ラフィーネインターナショナル, 株式会社免疫生物研究所
- Industrial Property Number
  2011-150487
- Filing Date
  2011-07-06
- Data Source
  KAKENHI-PROJECT-23792105
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2010
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 他
- Industrial Property Rights Holder
  広島大学,ラフィーネインターナショナル
- Industrial Property Number
  2010-136637
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-20592139
[Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2010
- Inventor(s)
  吉子裕二, 南崎朋子, 吉岡広陽, 香西克之, 渡邉和晃, 前田憲彦
- Industrial Property Rights Holder
  広島大学,ラフィーネインターナショナル
- Industrial Property Number
  2010-136637
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] ６：MEPE-derived ASARM, an inhibitor of calciparticle protein formation, suppresses vascular calcification but not bone formation2021
- Author(s)
  Davood Kharaghani, Tomoko Minamizaki, Shohei Kohno, Tomonori Hoshino, Yuji Yoshiko
- Organizer
  ASBMR 2021 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09816
[Presentation] ４：Calciprotein particles play a role in bone formation and vascular calcification2021
- Author(s)
  Davood Kharaghani, Eben Bashir Kurniawan, Shohei Kohno, Tomonori Hoshino, Tomoko Minamizaki, Yuji Yoshiko
- Organizer
  6th Joint Scientific Meeting in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09816
[Presentation] MiR-125b stored in bone matrix plays a role in osteoblast-osteoclast communication.2018
- Author(s)
  Tomoko Minamizaki, Yuji Yoshiko
- Organizer
  The 10th Annual Meeting of the Japanese Association for RNAi (JARI) The 5th Annual Meeting of Japanese Society of Extracellular Vesicles (JSEV)
- Data Source
  KAKENHI-PROJECT-16K11443
[Presentation] Nano-CT Analysis of Osteocyte Anomalies in Klotho-deficient Mice.2015
- Author(s)
  Minamizaki T, Sakurai K, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2015 Annual Meeting
- Place of Presentation
  Seattle, USA
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE-ASARM, a substrate of the neutral endopeptidase PHEX involved in rickets/osteomalacia, acts as an inhibitor of bone formation.2015
- Author(s)
  Sakurai K, Minamizaki T, Hayashi I, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  6th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  Hiroshima
- Year and Date
  2015-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE=ASARM, a substrate of Phex, decreases bone volume independently ofserum phosphate levels.2014
- Author(s)
  Sakurai K, Minamizaki T, Fujino Y, Takei Y, Yoshioka H, Okada M, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2014 Annual Meeting
- Place of Presentation
  Houston, TX, USA
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in klotho-deficient mice.2013
- Author(s)
  Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
- Organizer
  2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Imaging mass spectrometry-based molecular histology of bone shows the implication of MEPE-ASARM for the Klotho-deficient phonotype.2013
- Author(s)
  Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2013 Annual Meeting
- Place of Presentation
  Baltimore, MD, USA
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone.2012
- Author(s)
  Tomoko Minamizaki, Yukiko Konishi, Hirotaka Yoshioka, Kozai Kozai, Yuji Yoshiko
- Organizer
  The American Society for Bone and Mineral Research 2012 Annual Meeting
- Place of Presentation
  Minneapolis, USA
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] Phosphate Regulates Fibromodulin Expression Through the ERK Pathway in Ameloblasts2012
- Author(s)
  Yoshioka Hirotaka, Yoshiko Yuji, Irie Yasumasa, Minamizaki Tomoko, Kato Yukio, Sugiyama Toshihiro, Maeda Norihiko
- Organizer
  The 41st Annual Meeting of the American Association for Dental Research
- Place of Presentation
  Tampa, U.S.A
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone2012
- Author(s)
  Minamizaki Tomoko, Konishi Yukiko, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
- Organizer
  The American Society for Bone and Mineral Research 2012 Annual Meeting
- Place of Presentation
  Minneapolis, U.S.A.
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] 細胞外リン酸は ERK1/2 のシグナルを介してエナメル芽細胞における Fibromodulin 遺伝子の発現を抑制する2011
- Author(s)
  入江泰正,吉岡広陽,吉子裕二,南崎朋子,加藤幸夫,前田憲彦
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE-associated phosphorylated ASARM is a potential target to facilitate bone mineralization2011
- Author(s)
  Mohri Maya, Yoshiko Yuji, Minamizaki Tomoko, Yoshioka Hirotaka, Maeda Norihiko
- Organizer
  4th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  Hiroshima
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] 骨の石灰化調節に関わる可溶化型Klotho-FGF23 基軸2011
- Author(s)
  南崎朋子、吉子裕二、吉岡広陽、前田憲彦
- Organizer
  日本解剖学会第66回中国・四国支部学術集会
- Place of Presentation
  徳島
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] FGF シグナルによる石灰化調節:FGF23-Phex 経路を中心として2011
- Author(s)
  南崎朋子,吉子裕二,小西有希子,吉岡広陽,香西克之,前田憲彦
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE 由来リン酸化 ASARM と Phex は FGF23/可溶型Klotho による石灰化の負の調節系と関連する2011
- Author(s)
  小西有希子,吉子裕二,南崎朋子,吉岡広陽,香西克之,前田憲彦
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] MEPE-derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization2011
- Author(s)
  Konishi Yukiko, Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E. Aubin, Maeda Norihiko
- Organizer
  The American Society for Bone and Mineral Research 2011 Annual Meeting
- Place of Presentation
  San Diego, U.S.A
- Data Source
  KAKENHI-PROJECT-23792105
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization2010
- Author(s)
  Minamizaki T, 他
- Organizer
  The American Society for Bone and Mineral Research 2010 Annual Meeting
- Place of Presentation
  カナダ国トロント市
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization2010
- Author(s)
  Minamizaki T, 他
- Organizer
  The American Society for Bone and Mineral Research 2010 Annual Meeting
- Place of Presentation
  カナダ国トロント市
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010
- Author(s)
  Yoshioka H, Yoshiko Y, Minamizaki T, Nobukiyo A, Sotomaru Y, Suzuki A, Ito M, Maeda N.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Canada
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] 可溶化型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010
- Author(s)
  Yoshioka H, Yoshiko Y, Minamizaki T, et al.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し, 骨・ミネラル代謝異常の発症とともに増悪する2010
- Author(s)
  錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010
- Author(s)
  小西有希子, 吉子裕二, 南崎朋子, 吉岡広陽, 他
- Organizer
  第43回広島大学歯学会総会
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010
- Author(s)
  小西有希子, 吉子裕二, 南崎朋子, 北畠聖子, 吉岡広陽, 香西克之, 前田憲彦
- Organizer
  第43回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010
- Author(s)
  Minamizaki T, Yoshiko Y, Konishi Y、Yoshioka H, et al.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 可溶型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010
- Author(s)
  Minamizaki T, Yoshiko Y, Konishi Y, Yoshioka H, Kozai K, Aubin JE, Maeda N.
- Organizer
  The 32nd Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し,骨・ミネラル代謝異常の発症とともに増悪する2010
- Author(s)
  錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] 可溶化型Klothoは骨におけるFGF23の作用発現にリクルートされる2010
- Author(s)
  南崎朋子, 他
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009
- Author(s)
  小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第42回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009
- Author(s)
  南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] A Parathyroid Hormone-la, 25-dihydroxyvitamin D_3 FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  南崎朋子
- Organizer
  The 31st Annual Meeting for American Bone and Mineral Research
- Place of Presentation
  デンバー(アメリカ)
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] A Parathyroid Hormone-1α,25-dihydroxy-vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N
- Organizer
  The 31st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] PTHと活性型ビタミンD3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し、基質石灰化を調節する2009
- Author(s)
  南崎朋子
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] A parathyroid hormone-1α,25-dihydroxyvitamin D_3-FGF23 loop regulating bone mineralization in cultured rat calvaria osteoblasts2009
- Author(s)
  南崎朋子, et al.
- Organizer
  31th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
- Organizer
  第27回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] A Parathyroid Hormone-1α, 25-dihydroxy -vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009
- Author(s)
  Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N.
- Organizer
  The 31st Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Denver, USA
- Year and Date
  2009-09-14
- Data Source
  KAKENHI-PROJECT-21791788
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009
- Author(s)
  吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009
- Author(s)
  小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 他
- Organizer
  第42回広島大学歯学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] PTHと活性型ビタミンD3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し、基質石灰化を調節する2009
- Author(s)
  南崎朋子, 他
- Organizer
  第27回日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] FGF23 and FGF2 share a common but also have distinct signaling pathways for negative regulation of bone nodule mineralization in cultured osteoblasts.2008
- Author(s)
  Minamizaki T, Yoshiko Y, Suzuki S, et al.
- Organizer
  The 30th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Montreal
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 1,25(OH)_2D_3、PTHおよびKlothoはFGF23の基質石灰化抑制作用を直接調節する2008
- Author(s)
  南崎朋子, 吉子裕二, 前田憲彦
- Organizer
  第50回歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] FGF23 and FGF2 Share a Common but also Have Distinct Signaling Pathways for Negative Regulation of Bone Nodule Mineralization in Cultured Osteoblasts.2008
- Author(s)
  Tomoko Minamizaki
- Organizer
  The 30th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  モントリオール, カナダ
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] FG23 and FGF2 share a common but also have distinct signaling path ways for negative regulation of bone nodule mineralization in cultured osteoblasts.2008
- Author(s)
  Tomoko Minamizaki
- Organizer
  30th Annual Meeting of the America Society for Bone and Mineral Research
- Place of Presentation
  Montreal, Canada
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-20592139
[Presentation] 1, 25(OH)_2D_3、PTHおよびklothoはFGF23の基質石灰化抑制作用を直接調節する2008
- Author(s)
  南崎朋子
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] 1.25(OH)2D3 inhibits bone nodule mineralization through the FGF23-mediating ERK pathway in rat calvaria osteoblast cultures.2007
- Author(s)
  Minamizaki, T
- Organizer
  29th Annual Meeting of the American Mineral Society for Bone and Mineral Research
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19890140
[Presentation] Phexの基質MEPE-ASARMは血中リン濃度非依存的に骨量を減少させる
- Author(s)
  櫻井薫、南崎朋子、吉岡広陽、竹井悠一郎、香西克之、吉子裕二
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] MEPE-ASARM, a substrate of Phex, decreases bone volume independently of serum phosphate levels
- Author(s)
  Sakurai K, Minamizaki T, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
- Organizer
  The American Society for Bone and Mineral Research 2014 Annual Meeting
- Place of Presentation
  Houston（USA）
- Year and Date
  2014-09-12 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] Klotho欠損マウス腎臓のイメージング質量分析
- Author(s)
  藤野陽子、南崎朋子、宮脇聡子、川上朝子、宮地孝明、櫻井薫、竹井悠一郎、吉岡広陽、香西克之、岡田貢、吉子裕二
- Organizer
  日本解剖学会第69回中国・四国支部学術集会
- Place of Presentation
  広島
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25462858
[Presentation] 骨基質タンパクMEPE-由来ASARMは血中リン濃度非依存的に骨量を減少させる
- Author(s)
  櫻井薫、南崎朋子、川本真貴子、藤野陽子、竹井悠一郎、吉岡広陽、岡田貢、香西克之、吉子裕二
- Organizer
  日本解剖学会第69回中国・四国支部学術集会
- Place of Presentation
  広島
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25462858

1. YOSHIKO Yuji (20263709)

# of Collaborated Projects: 6 results

# of Collaborated Products: 44 results
2. KOZAI Katsuyuki (10178212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. YOSHIOKA Hirotaka (50523411)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
4. FUTAMURA MANABU (10415515)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. UCHIDA Soshi (60330990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 河野尚平 (00868391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 新飯田俊平 (10137630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ahmed Faisal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Sarmin Nushrat

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Zaurasari Mentari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 竹井悠一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MINAMIZAKI Tomoko 南崎 朋子

Research Projects

Research Products

Co-Researchers

クロマチンと遺伝子発現の網羅的解析の併用による組織特異的石灰化機序の同定

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Review Section

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miR-125bを導入した基質小胞による癌骨転移治療の検討Principal Investigator

Principal Investigator

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Review Section

Research Institution

A trial of miRNAs derived from bone matrix as an inhibitor for bone metastasisPrincipal Investigator

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The roles of downstream factor(s) of cancer cell-derived Klotho on bone mineralizationPrincipal Investigator

Principal Investigator

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A basic study of de novo function of PTH in mineral metabolism disordersPrincipal Investigator

Principal Investigator

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A basic study of Klotho as a local factor of hard tissue reproductionPrincipal Investigator

Principal Investigator

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A basic study on FGF23 for molecular targeted therapy of bone/tooth diseases

Principal Investigator

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局所リン酸代謝調節に基づく新規の骨・歯科疾患治療の基礎的研究Principal Investigator

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[Journal Article] The bioactive acidic serine- and aspartate-rich motif peptide.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Functional Diversity of Fibroblast Growth Factors in Bone Formation.2015

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DOI

NAID

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[Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

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[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures.2012

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DOI

NAID

Data Source

[Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Incisor snemal formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

MINAMIZAKI Tomoko 南崎朋子

[Journal Article] Functional Diversity of Fibroblast Growth Factors in Bone　Formation.2015