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YOSHIOKA Hirotaka  吉岡 広陽

ORCIDConnect your ORCID iD *help
Researcher Number 50523411
Affiliation *help 2017 : 国際医療福祉大学, 医学部, 講師
2012 – 2016 : 広島大学, 医歯薬保健学研究院(歯), 助教
2009 – 2012 : 広島大学, 医歯(薬)学総合研究科, 助教
2012 : 広島大学, 大学院・医歯薬保健学研究院, 助教
2009 – 2011 : Hiroshima University, 大学院・医歯薬学総合研究科, 助教
2010 : 広島大学, 医歯薬学総合研究科, 助教
2008 : 広島大学, 医歯薬保健学研究院(歯), 助教
Review Section/Research Field
Principal Investigator
Morphological basic dentistry
Except Principal Investigator
Morphological basic dentistry
Keywords
Principal Investigator
リン酸代謝 / 石灰化 / エピジェネティクス / 骨代謝 / 歯 / エナメル質 / Bone lining cells / 骨芽細胞 / 発生・分化 / リン代謝 … More / 歯牙形成 / 細胞・組織 / 歯胚 / 骨形成 … More
Except Principal Investigator
骨芽細胞 / FGF23 / GF23 / 可溶型Klotho / リン代謝 / PTH / Klotho / 石灰化 / KLotho / 細胞・組織 / マウス / マップキナーゼ(ERK) / 歯・骨の石灰化 / 骨代謝 / 可溶化Klotho(細胞外ドメイン) / ERK Less
  • Research Projects

    (7results)
  • Research Products

    (75results)
  • Co-Researchers

    (11People)
  •  単一細胞解析による骨芽細胞の運命制御機構の解明と新規骨形成促進剤の標的分子探索Principal InvestigatorOngoing

    • Principal Investigator
      吉岡 広陽
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      International University of Health and Welfare
  •  Development of bone regeneration strategies by controlling the epigenetic state of bone lining cells.Principal Investigator

    • Principal Investigator
      YOSHIOKA HIROTAKA
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Study of tooth morphogenesis from the aspect of local regulation of phosphate metabolism: An epigenomic approach.Principal Investigator

    • Principal Investigator
      YOSHIOKA Hirotaka
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  A basic study of de novo function of PTH in mineral metabolism disorders

    • Principal Investigator
      MINAMIZAKI Tomoko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Tooth morphogenesis and the regulation of phosphate homeostasis : basic and preclinical studies of tooth hypoplasiaPrincipal Investigator

    • Principal Investigator
      YOSHIOKA Hirotaka
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  リン酸代謝を分子基盤とした歯の石灰化不全の解析と実験的治療Principal Investigator

    • Principal Investigator
      吉岡 広陽
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity start-up
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  A basic study on FGF23 for molecular targeted therapy of bone/tooth diseases

    • Principal Investigator
      YOSHIKO Yuji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University

All 2017 2016 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Comparative proteome analysis of wild-type and klotho-knockout mouse kidneys using a combination of MALDI-IMS and LC-MS/MS.2017

    • Author(s)
      Fujino Y, Minamizaki T, Hayashi I, Kawakami A, Miyaji T, Sakurai K, Yoshioka H, Kozai K, Okada M, Yoshiko Y.
    • Journal Title

      Proteomics Clin. Appl.

      Volume : 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460067, KAKENHI-PROJECT-26462785
  • [Journal Article] Imaging and mapping of mouse bone using MALDI-imaging mass spectrometry.2016

    • Author(s)
      Fujino Y, Minamizaki T, Yoshioka H, Okada M, Yoshiko Y
    • Journal Title

      Bone Reports

      Volume : 5 Pages : 280-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Journal Article] The dynamics of DNA methylation and hydroxymethylation during amelogenesis.2015

    • Author(s)
      Yoshioka H, Minamizaki T, Yoshiko Y.
    • Journal Title

      Histochemistry and Cell Biology

      Volume : 144 Pages : 471-478

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Journal Article] Sequence-specific promoter elements regulate temporal-specific changes in chromatin required for testis-specific activation of the Pgk2 gene2013

    • Author(s)
      Yang Z, Yoshioka H, McCarrey JR
    • Journal Title

      Reproduction

      Volume : 146 Pages : 501-516

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

    • Author(s)
      Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, KOzai Katsuyuki, Aubin Jane E, Maeda Norihiko
    • Journal Title

      Prostaglandins Other Lipid Mediat

      Volume : 97 Pages : 97-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
  • [Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a1.2012

    • Author(s)
      Yoshioka Hirotaka, Yoshiko Yuji, Minamizaki Tomoko, Suzuki Sayaka, Koma Yoshiro, Nobukiyo Asako, Sotomaru Yusuke, Suzuki Atsushi, Ito Mitsuyasu, Maeda Norihiko
    • Journal Title

      Calcif Tissue Int.

      Volume : 89 Pages : 192-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792105, KAKENHI-PROJECT-22791768, KAKENHI-PROJECT-23592701
  • [Journal Article] The EP4-ERK-dependent pathway stimulatesosteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvariacell cultures2012

    • Author(s)
      Minamizaki T, Yoshiko Y, Yoshioka H, Kozai K, Aubin JE, Maeda N
    • Journal Title

      Prostaglandins and Other Lipid Mediators

      Volume : 97 Pages : 97-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

    • Author(s)
      Yoshioka Hirotaka, Yoshiko Yuji, Minamizaki Tomoko, Suzuki Sayaka, Koma Yoshiro, Nobukiyo Asako, Sotomaru Yusuke, Suzuki Atsushi, Ito Mitsuyasu, Maeda Norihiko
    • Journal Title

      Calcif Tissue Int

      Volume : 89 Pages : 192-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

    • Author(s)
      Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E Aubin, Maeda Norihiko
    • Journal Title

      Prostaglandins Other Lipid Mediat

      Volume : 97 Pages : 97-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Journal Article] Incisor enamel formation is impairedin transgenic rats overexpressing the type III NaPi transporter Slc20a12011

    • Author(s)
      Yoshioka H, Yoshiko Y, Minamizaki T, Suzuki S, Koma Y, Nobukiyo A, SotomaruY, Suzuki A, Itoh M and Maeda N
    • Journal Title

      Calcified Tissue International

      Volume : 89 Pages : 192-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Journal Article] 1α, 25(OH) 2D acts predominantly onmature osteoblastic cells under conditions of high extracellular phosphate to increase FGF23 productionin vitro2010

    • Author(s)
      Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, Tanne S, Aubin JE, Maeda N
    • Journal Title

      Journal of Endocrinology

      Volume : 206 Pages : 279-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Journal Article] 1・,25-dihydroxy-vitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010

    • Author(s)
      Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, et al.
    • Journal Title

      J Endocrinol 206(3)

      Pages : 279-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] 低リン血症にみる歯の形成の分子基盤2008

    • Author(s)
      吉子裕二, 南崎朋子, 吉岡広陽, 鈴木清香, 前田憲彦
    • Journal Title

      広島歯誌 36

      Pages : 1-12

    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] 骨芽細胞の多様性と脂肪細胞への分化転換2016

    • Author(s)
      沖田紗季,吉岡広陽,南崎朋子,谷本幸太郎,吉子裕二
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] シングルセルRNA-seqによる骨芽細胞の多様性の解析2016

    • Author(s)
      沖田紗季,吉岡広陽,南崎朋子,谷本幸太郎,吉子裕二
    • Organizer
      日本解剖学会第71回中国・四国支部学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Histomorphometric analysis of Klotho-deficient mice by nano-CT.2016

    • Author(s)
      Ahmed F,Minamizaki T,Yoshioka H,Yoshiko Y
    • Organizer
      日本解剖学会第71回中国・四国支部学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Osteoblasts inhibit osteoclast formation by targeting Prdm1 via the mechanism underlying matrix vesicle-mediated transfer of miR-125b.2016

    • Author(s)
      Irie Y, Minamizaki T, Ahmed F, Nakao Y, Yoshioka H, Tanimoto K, Kozai K, Yoshiko Y
    • Organizer
      The American Society of Bone and Mineral Research 2016 Annual Meeting
    • Place of Presentation
      Atlanta, GA, USA
    • Year and Date
      2016-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Matrix vesicle miR-125b suppress osteoclast formation by targeting Prdm1.2016

    • Author(s)
      Irie Y, Minamizaki T, Nakao Y, Ahmed F, Yoshioka H, Kozai K, Tanimoto K, Yoshiko Y
    • Organizer
      Annual Meetings of the Endocrine Society of Australia and Society for Reproductive Biology and Australia and New Zealand Bone and Mineral Society 2016
    • Place of Presentation
      Queensland, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] MicroRNA-125b in bone matrix plays a crucial role in osteoblast-osteoclast communication.2016

    • Author(s)
      Minamizaki T, Takei Y, Nakao Y, Irie Y, Yoshioka H, Tanimoto K, Kozai K, Yoshiko Y
    • Organizer
      43rd Annual European Calcified Tissue Society Congress
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2016-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] 骨芽細胞は基質小胞を介してmiR-125bを輸送し,Prdm1を標的として破骨細胞の形成を抑制する2016

    • Author(s)
      入江泰正,南崎朋子,中尾裕子,Faisal Ahmed,吉岡広陽,香西克之,竹井悠一郎,吉子裕二
    • Organizer
      第34回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Matrix Vesicles Mediate the Cell-to-Cell Transmission of MicroRNA-125b as an Inhibitor of Osteoclastic Bone Resorption.2015

    • Author(s)
      Takei Y, Nakao Y, Minamizaki T, Irie Y, Ahmed F, Yoshioka H, Niida S, Tanimoto K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] MicroRNAs Involved in Bone Metabolism Are Transported into Matrix Vesicles during Bone Formation.2015

    • Author(s)
      Nakao Y, Takei Y, Minamizaki T, Yoshioka H, Ahmed F, Tanimoto K, Niida S, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] A Novel isoform of FGFR2 Modulates FGF10-FGFR Signaling in Osteochondrogenesis.2015

    • Author(s)
      Yoshioka H, Kagawa K, Okita S, Kuremoto K, Takei Y, Minamizaki T, Tanimoto K, Tsuga K, Yoshiko Y
    • Organizer
      6th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2015-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Bone-derived miRNA as a mediator of cell-cell communication.2015

    • Author(s)
      Takei Y, Minamizaki T, Yoshioka H, Yoshiko Y
    • Organizer
      6th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2015-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Newly Identified FGFR2 Isoform Modulates FGF10-FGFR Signaling During Osteochondrogenesis.2015

    • Author(s)
      Kagawa K, Yoshioka H, Okita S, Kuremoto K, Takei Y, Minamizaki T, Tanimoto K, Tsuga K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] マウス歯胚発生過程におけるDNA メチル化酵素Dnmt1 の役割2013

    • Author(s)
      大西梓, 吉岡広陽, 南崎朋子, 吉子裕二
    • Organizer
      第118回日本解剖学会総会・学術集会
    • Place of Presentation
      高松
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] マウス歯胚発生過程におけるDNAメチル化酵素Dnmt1の役割2013

    • Author(s)
      大西 梓,吉岡 広陽,南崎 朋子,吉子 裕二
    • Organizer
      第118回 日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川県高松市
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in Klotho-deficient mice2013

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      5th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Imaging mass spectrometry-based molecular histology of bone shows the implication of MEPE-ASARM for the Klotho-deficient phenotype2013

    • Author(s)
      Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2013 Annual Meeting
    • Place of Presentation
      Baltimore, USA
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] マウス歯胚発生過程におけるエピジェネティクス制御機構の解明2013

    • Author(s)
      吉岡広陽, 南崎朋子, 吉子裕二
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2013-09-21
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in Klotho-deficient mice2013

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      2nd Joint Meeting of International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in klotho-deficient mice.2013

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y.
    • Organizer
      2nd Joint Meeting of International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Imaging Mass Spectrometry-based Molecular Histology of Bone Shows the Implication of MEPE-ASARM for the Klotho-Deficient Phenotype.2013

    • Author(s)
      Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y.
    • Organizer
      The American Society for Bone and Mineral Research 2013 Annual Meeting
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Phosphate Regulates Fibromodulin Expression Through theERK Pathway in Ameloblasts2012

    • Author(s)
      Yoshioka H, Yoshiko Y, Irie Y, Minamizaki T, Kato Y, Sugiyama T, Maeda N
    • Organizer
      The 41^<st> Annual Meeting of the AmericanAssociation for Dental Research
    • Place of Presentation
      Tampa, FL, USA
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Phosphate Regulates Fibromodulin Expression Tlarough the ERK Pathway in Ameloblasts2012

    • Author(s)
      吉岡広陽
    • Organizer
      41^<st> Annual Meeting of the American Association for Dental Research
    • Place of Presentation
      アメリカ合衆国フロリダ州タンパ
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Transient but not constitutive activation of ERK is necessary for the unique action of FGF23 in bone2012

    • Author(s)
      Minamizaki T, Konishi Y, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      The 34th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Minneapolis, USA
    • Data Source
      KAKENHI-PROJECT-24791962
  • [Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone.2012

    • Author(s)
      Tomoko Minamizaki, Yukiko Konishi, Hirotaka Yoshioka, Kozai Kozai, Yuji Yoshiko
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, USA
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] Phosphate Regulates Fibromodulin Expression Through the ERK Pathway in Ameloblasts2012

    • Author(s)
      Yoshioka Hirotaka, Yoshiko Yuji, Irie Yasumasa, Minamizaki Tomoko, Kato Yukio, Sugiyama Toshihiro, Maeda Norihiko
    • Organizer
      The 41st Annual Meeting of the American Association for Dental Research
    • Place of Presentation
      Tampa, U.S.A
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone2012

    • Author(s)
      Minamizaki Tomoko, Konishi Yukiko, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, U.S.A.
    • Year and Date
      2012-10-15
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] FGFシグナルによる石灰化調節:FGF23-Phex経路を中心として2011

    • Author(s)
      南崎朋子, 吉子裕二, 小西有希子, 吉岡広陽, 香西克之, 前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] MEPE由来リン酸化ASARMとPhexはFGF23/可溶型Klothoによる石灰化の負の調節系と関連する2011

    • Author(s)
      小西有希子, 吉子裕二, 南崎朋子, 吉岡広陽, 香西克之, 前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] 細胞外リン酸はERK1/ 2シグナルを介してエナメル芽細胞におけるFibromodulin遺伝子の発現を抑制する2011

    • Author(s)
      入江泰正, 吉岡広陽, 吉子裕二, 南崎朋子, 加藤幸夫, 前田憲彦
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Shimizu A, AubinJ, Maeda N. MEPE-Derived Phosphorylated ASARM Is Involved inFGF23/ soluble Klotho-DependentHypomineralization2011

    • Author(s)
      Konishi Y, Yoshiko Y, Minamizaki T, Yoshioka H, Maeda M, Shimizu A, AubinJ, Maeda N
    • Organizer
      The 33rd AnnualMeeting of the American Society forBone and Mineral Research
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] FGF シグナルによる石灰化調節:FGF23-Phex 経路を中心として2011

    • Author(s)
      南崎朋子,吉子裕二,小西有希子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE 由来リン酸化 ASARM と Phex は FGF23/可溶型Klotho による石灰化の負の調節系と関連する2011

    • Author(s)
      小西有希子,吉子裕二,南崎朋子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE-associated phosphorylated ASARM is a potential target to facilitate bone mineralization2011

    • Author(s)
      Mohri Maya, Yoshiko Yuji, Minamizaki Tomoko, Yoshioka Hirotaka, Maeda Norihiko
    • Organizer
      4th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima
    • Year and Date
      2011-10-10
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] 骨の石灰化調節に関わる可溶化型Klotho-FGF23 基軸2011

    • Author(s)
      南崎朋子、吉子裕二、吉岡広陽、前田憲彦
    • Organizer
      日本解剖学会第66回中国・四国支部学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE-derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization2011

    • Author(s)
      Konishi Yukiko, Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E. Aubin, Maeda Norihiko
    • Organizer
      The American Society for Bone and Mineral Research 2011 Annual Meeting
    • Place of Presentation
      San Diego, U.S.A
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] 細胞外リン酸は ERK1/2 のシグナルを介してエナメル芽細胞における Fibromodulin 遺伝子の発現を抑制する2011

    • Author(s)
      入江泰正,吉岡広陽,吉子裕二,南崎朋子,加藤幸夫,前田憲彦
    • Organizer
      第53回 歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but notin Kidney to Regulate Mineralization2010

    • Author(s)
      Minamizaki T, Yoshiko Y, Konishi Y, Yoshioka H, Kozai K, Aubin JE, MaedaN
    • Organizer
      The32nd Annual Meeting of theAmerican Society for Bone and MineralResearch
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Overexpression of the type IIIsodium-dependent phosphatetransporter Pit1 markedly perturbsenamel formation during toothdevelopment2010

    • Author(s)
      Yoshioka H, Yoshiko Y, Minamizaki T, Suzuki A, Itoh M, Maeda N
    • Organizer
      The32nd Annual Meetingof the American Society for Bone andMineral Research
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Overexpression of the Type III Sodium-dependent Phosphate Transporter Pit1 Markedly Perturbs Enamel Formation during Tooth Development2010

    • Author(s)
      Yoshioka H, 他
    • Organizer
      The American Society for Bone and Mineral Research 2010 Annual Meeting
    • Place of Presentation
      カナダ国 トロント市
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] 可溶型Klothoは骨におけるFGF23の作用発現にリクルートされる2010

    • Author(s)
      南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010

    • Author(s)
      吉岡広陽, 他
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し,骨・ミネラル代謝異常の発症とともに増悪する2010

    • Author(s)
      錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し, 骨・ミネラル代謝異常の発症とともに増悪する2010

    • Author(s)
      錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010

    • Author(s)
      Yoshioka H, Yoshiko Y, Minamizaki T, et al.
    • Organizer
      The 32nd Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Toronto
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010

    • Author(s)
      Minamizaki T, Yoshiko Y, Konishi Y、Yoshioka H, et al.
    • Organizer
      The 32nd Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010

    • Author(s)
      小西有希子, 吉子裕二, 南崎朋子, 北畠聖子, 吉岡広陽, 香西克之, 前田憲彦
    • Organizer
      第43回広島大学歯学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010

    • Author(s)
      吉岡広陽
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development2010

    • Author(s)
      吉岡広陽
    • Organizer
      2010 Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      カナダ オンタリオ州トロント
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-22791768
  • [Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010

    • Author(s)
      小西有希子, 吉子裕二, 南崎朋子, 吉岡広陽, 他
    • Organizer
      第43回広島大学歯学会総会
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体 Pit1過剰発現ラットはエナメル質の形成不全を来す2009

    • Author(s)
      吉岡広陽
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪市
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-21890156
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009

    • Author(s)
      吉岡広陽
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      新潟市
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21890156
  • [Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009

    • Author(s)
      南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質形成不全を来す2009

    • Author(s)
      吉岡広陽, 他
    • Organizer
      第27回日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] A Parathyroid Hormone-1α,25-dihydroxy-vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009

    • Author(s)
      Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N
    • Organizer
      The 31st Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Denver, USA
    • Year and Date
      2009-09-14
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009

    • Author(s)
      小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第42回広島大学歯学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009

    • Author(s)
      南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] マウス歯胚発生過程におけるエピジェネティクス制御機構の解明

    • Author(s)
      吉岡広陽,南崎朋子,吉子裕二
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山県岡山市
    • Data Source
      KAKENHI-PROJECT-24791962
  • 1.  YOSHIKO Yuji (20263709)
    # of Collaborated Projects : 4results
    # of Collaborated Products : 42results
  • 2.  MINAMIZAKI Tomoko (30452593)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 42results
  • 3.  UCHIDA Soshi (60330990)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 4.  KOZAI Katsuyuki (10178212)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 7results
  • 5.  NIIDA Shunpei (10137630)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 2results
  • 6.  TAKEI Yuichiro
    # of Collaborated Projects : 1results
    # of Collaborated Products : 7results
  • 7.  HIYAMA Shinji
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 8.  KAGAWA Kazuko
    # of Collaborated Projects : 1results
    # of Collaborated Products : 2results
  • 9.  OKITA Saki
    # of Collaborated Projects : 1results
    # of Collaborated Products : 4results
  • 10.  NAKANO Masashi
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 11.  Miyaji Takaaki
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results

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