Hikosaka Kenji 彦坂健児

… Alternative Names

彦坂健児ヒコサカケンジ

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Researcher Number	30456933
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2025: 千葉大学, 大学院医学研究院, 准教授 2021 – 2023: 千葉大学, 大学院医学研究院, 准教授 2018 – 2020: 千葉大学, 大学院医学研究院, 講師 2017: 千葉大学, 大学院医学研究院, 特任講師 2015: 千葉大学, 医学(系)研究科(研究院), 特任助教 2014: 帝京大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 49040:Parasitology-related / Parasitology (including sanitary zoology) Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 49040:Parasitology-related / Complex Systems Disease Theory
Keywords	Principal Investigator ミトコンドリア / マラリア原虫 / ミトコンドリアゲノム / 薬剤耐性 / Plasmodium / マラリア / パーシスター細胞 / DNAメチル化 / 偽シスト / 腟トリコモナス症 … More / 翻訳 / アフィニティ精製 / リボソームタンパク質 / ミトコンドリアリボソーム / TAP法 / 翻訳機構 / リボソーム / 人工ミトコンドリアDNA / 組換え / mtDNA組換え / 組換え原虫 / rho0細胞 / ミトコンドリアDNA / 動物感染モデル / アトバコン / 抗マラリア薬 … More Except Principal Investigator トキソプラズマ / 感染症 / トキソプラズマ症 / アフリカ / スペクトロスコピー / インピーダンス / 電気計測 / 神経炎症 / Hypericum / ヒペリシン / うつ病 / グリア細胞 / 脳 / ハイパーフォリン / 西洋オトギリソウ / 炎症 / 神経系 / 薬用植物 / 寄生虫 / 病原性 / 次世代シーケンサー / ゲノム / ゲノム解析 / 薬剤耐性 / 日和見感染症 / インターフェロンガンマノックアウトマウス / 全ゲノム解析 / 病原性関連遺伝子 / 全ゲノム配列 / 分子疫学 / シスト / 重症度評価法 / 再活性化検出法 / ステージ変換 / 重症化 / 再活性化 / 質量分析 Less

The role of DNA methylation in regulating dormancy mechanisms of Trichomonas vaginalisPrincipal Investigator
- Principal Investigator
  
  彦坂健児
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Chiba University
A study on a low-cost translation mechanism in the mitochondrial ribosome of the malaria parasitePrincipal Investigator
- Principal Investigator
  
  Hikosaka Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Chiba University
ラベルフリーで多重感染定量検出可能なCD型EISのケニアにおける検証研究
- Principal Investigator
  
  武居昌宏
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Chiba University
Elucidation of molecular epidemiological information of Toxoplasma gondii using whole genome sequence and identification of pathogenicity-related genes
- Principal Investigator
  
  Norose Kazumi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Shinshu University
  Chiba University
Anti-Toxoplasma and neuroprotective potential of medicinal plant Hypericum
- Principal Investigator
  
  Shinjyo Noriko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Osaka University
  Chiba University
Establishment of the detection method for the reactivation of toxoplasmosis and the evaluatiion method for the severity of toxoplasmosis by mass spectrometer
- Principal Investigator
  
  NOROSE Kazumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Chiba University
A study towards establishing a cell line depleted of mitochondrial DNA in malaria parasitesPrincipal Investigator
- Principal Investigator
  
  Hikosaka Kenji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Chiba University
Mutation patterns of mitochondrial DNA in atovaquone-resistant malaria parasitesPrincipal Investigator
- Principal Investigator
  
  Hikosaka Kenji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Chiba University
  Teikyo University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Book

[Book] An Overview of Tropical Diseases -Mitochondria of Malaria Parasites as A Drug Target2015
- Author(s)
  Hikosaka K, Komatsuya K, Suzuki S, Kita K
- Total Pages
  18
- Publisher
  Intech
- Data Source
  KAKENHI-PROJECT-26860277
[Book] An Overview of Tropical Diseases, Chapter 2, Mitochondria of malaria parasites as a drug target2015
- Author(s)
  Hikosaka K, Komatsuya K, Suzuki S, Kita K
- Publisher
  Intech
- Data Source
  KAKENHI-PROJECT-26860277
[Journal Article] Sinusoidal obstruction syndrome associated with disseminated toxoplasmosis involving the liver after allogeneic hematopoietic stem cell transplantation: A case report2023
- Author(s)
  Makuuchi Y、Tanaka S、Koh H、Niki M、Norose K、Nakaya Y、Ido K、Sakatoku K、Kuno M、Harada N、Takakuwa T、Hirose A、Okamura H、Nishimoto M、Nakashima Y、Nakamae M、Hikosaka K、Kakeya H、Ohsawa M、Hino M, Nakamae Hi
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 29 Issue: 9 Pages: 909-912
- DOI
  10.1016/j.jiac.2023.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Genetic relatedness of third-generation cephalosporin-resistant Escherichia coli among livestock, farmers, and patients in Japan2023
- Author(s)
  Nakano Ryuichi、Nakano Akiyo、Nishisouzu Ryuji、Hikosaka Kenji、Suzuki Yuki、Kamoshida Go、Tansho-Nagakawa Shigeru、Endo Shiro、Kasahara Kei、Ono Yasuo、Yano Hisakazu
- Journal Title
  
  One Health
  
  Volume: 16 Pages: 100524-100524
- DOI
  10.1016/j.onehlt.2023.100524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10403, KAKENHI-PROJECT-19K08948, KAKENHI-PROJECT-20K10433, KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-21K07010
[Journal Article] Development of a novel electroporation method for the oyster parasite Perkinsus marinus.2022
- Author(s)
  Sakamoto H, Lin XX, Bai YD, Chen XF, Zhang ZZ, Honjo Y, Hikosaka K.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 19996-19996
- DOI
  10.1038/s41598-022-24548-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-19K16627, KAKENHI-PROJECT-20K07461, KAKENHI-PUBLICLY-22H04633
[Journal Article] Siccanin is a dual-target inhibitor of Plasmodium falciparum mitochondrial complex II and complex III.2022
- Author(s)
  Komatsuya K, Sakura T, Shiomi K, Omura S, Hikosaka K, Nozaki T, Kita K, Inaoka DK.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 7 Pages: 903-903
- DOI
  10.3390/ph15070903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-20K07461
[Journal Article] 既存薬剤に耐性を示す腟トリコモナスに対する７種の生薬の効果2022
- Author(s)
  本庄唯意、平崎能郎、糸山頌理、新倉　保、林　暁霞、坂本寛和、野呂瀬一美、生水真紀夫、彦坂健児.
- Journal Title
  
  Clin Parasitol
  
  Volume: 33 Pages: 55-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] 複数回の肛囲検査では虫卵が検出されず、虫体から診断に至った蟯虫症の一例2022
- Author(s)
  中川良太、栗原恵理佳、野呂瀬一美、彦坂健児、金澤正樹、寺井　勝
- Journal Title
  
  Clin Parasitol
  
  Volume: 33 Pages: 72-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] 感染源が不明であったドロレス顎口虫による皮膚爬行症の 1例2022
- Author(s)
  熊田　大樹、猪爪　隆史、栗田　遼二、野呂瀬　一美、彦坂　健児、丸山　治彦、松江　弘之
- Journal Title
  
  皮膚科の臨床
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-19K07839
[Journal Article] 感染源が不明であったドロレス顎口虫による皮膚爬行症の1例2022
- Author(s)
  熊田　大樹、猪爪　隆史、栗田　遼二、野呂瀬　一美、彦坂　健児、丸山　治彦、松江　弘之
- Journal Title
  
  皮膚科の臨床
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] 感染源が不明であったドロレス顎口虫による皮膚爬行症の1例2022
- Author(s)
  熊田大樹、猪爪隆史、栗田遼二、野呂瀬一美、彦坂健児、丸山治彦、松江弘之
- Journal Title
  
  皮膚科の臨床
  
  Volume: 64 Pages: 1727-1730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Erdheim-Chester Disease Involving the Central Nervous System with Latent Toxoplasmosis2022
- Author(s)
  Wadayama Tomoya、Shimizu Mikito、Kimura Ikko、Baba Kousuke、Beck Goichi、Nagano Seiichi、Morita Ryo、Nakagawa Hidenori、Shirano Michinori、Goto Tetsushi、Norose Kazumi、Hikosaka Kenji、Murayama Shigeo、Mochizuki Hideki
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 17 Pages: 2661-2666
- DOI
  10.2169/internalmedicine.8564-21
- NAID
  130008158352
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-09-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06910, KAKENHI-PROJECT-20K07461, KAKENHI-PROJECT-22K07538, KAKENHI-PROJECT-22K07539, KAKENHI-PROJECT-22K07550, KAKENHI-PROJECT-19K07988
[Journal Article] トキソプラズマ症のPCRによる診断2022
- Author(s)
  彦坂　健児
- Journal Title
  
  病原微生物検出情報
  
  Volume: 43 Pages: 60-61
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] New PCR primers targeting the cytochrome b gene reveal diversity of Leucocytozoon lineages in an individual host.2022
- Author(s)
  Honjo Y, Fukumoto S, Sakamoto H, Hikosaka K.
- Journal Title
  
  Parasitol Res.
  
  Volume: 121 Issue: 11 Pages: 3313-3320
- DOI
  10.1007/s00436-022-07667-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-19K16627, KAKENHI-PROJECT-20K07461, KAKENHI-PUBLICLY-22H04633
[Journal Article] Murine Model of Primary Acquired Ocular Toxoplasmosis: Fluorescein Angiography and Multiplex Immune Mediator Profiles in the Aqueous Humor2021
- Author(s)
  Li Kexin、Feng Xue、Hikosaka Kenji、Norose Kazumi
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 62 Issue: 3 Pages: 9-9
- DOI
  10.1167/iovs.62.3.9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-19K07520
[Journal Article] Hypericum perforatum extract and hyperforin inhibit the growth of neurotropic parasite Toxoplasma gondii and infection-induced inflammatory responses of glial cells in vitro2021
- Author(s)
  Shinjyo Noriko、Nakayama Hideyuki、Li Li、Ishimaru Kanji、Hikosaka Kenji、Suzuki Noriyuki、Yoshida Hiroki、Norose Kazumi
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 267 Pages: 113525-113525
- DOI
  10.1016/j.jep.2020.113525
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-20K07461, KAKENHI-PROJECT-19K07520
[Journal Article] Toxoplasma Infection Induces Sustained Up-Regulation of Complement Factor B and C5a Receptor in the Mouse Brain via Microglial Activation: Implication for the Alternative Complement Pathway Activation and Anaphylatoxin Signaling in Cerebral Toxoplasmosis2021
- Author(s)
  Shinjyo N, Hikosaka K, Kido Y, Yoshida H, Norose K.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 603924-603924
- DOI
  10.3389/fimmu.2020.603924
- NAID
  120007000273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-18KK0454
[Journal Article] Development of a rapid scabies immunodiagnostic assay based on transcriptomic analysis of Sarcoptes scabiei var. nyctereutis2021
- Author(s)
  Akuta T, Minegishi D. Kido N, Imaizumi K, Nakaoka S, Tachibana S, Hikosaka K, Hori F, Masataka N, Sakuma C, Oouchi Y, Nakajima Yu, Tanaka S, Omiya T, Morikaku K, Kawahara M, Tada Y, Tarui H, Ueda T, Kikuchi-Ueda T, Ono Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 6455-6455
- DOI
  10.1038/s41598-021-85290-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K07461
[Journal Article] Acute exacerbation of pulmonary toxoplasmosis during corticosteroid therapy for immune thrombocytopenia2021
- Author(s)
  Omori Koji、Imoto Naoto、Norose Kazumi、Maeda Matsuyoshi、Hikosaka Kenji、Kurahashi Shingo
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 51 Pages: e28430-e28430
- DOI
  10.1097/md.0000000000028430
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K07461
[Journal Article] Clinical characteristics and incidence of toxoplasmosis after autologous hematopoietic stem cell transplantation: A retrospective study and literature review2021
- Author(s)
  Kitahara Mari、Hiroshima Yuki、Norose Kazumi、Hikosaka Kenji、Kazumoto Hiroko、Uematsu Nozomu、Shishido Tsutomu、Kaiume Hiroko、Sato Keijiro、Ueki Toshimitsu、Sumi Masahiko、Watanabe Masahide、Kobayashi Hikaru
- Journal Title
  
  Transplant Infectious Disease
  
  Volume: 23 Issue: 6
- DOI
  10.1111/tid.13726
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K07461
[Journal Article] Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria.2020
- Author(s)
  Ajibaye O, Osuntoki AA, Balogun EO, Olukosi YA, Iwalokun BA, Oyebola KM, Hikosaka K, Watanabe YI, Ebiloma GU, Kita K, Amambua-Ngwa A.
- Journal Title
  
  Malar J.
  
  Volume: 19 Issue: 1 Pages: 6-6
- DOI
  10.1186/s12936-019-3096-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-17K15676
[Journal Article] Pseudo-‘Pneumatosis intestinalis’ sign: A case of parasite uniquely depicted on postmortem CT.2020
- Author(s)
  Yoshida M, Hoshioka Y, Makino Y, Kojima M, Horikoshi T, Mukai H, Hikosaka K, Norose K, Iwase H.
- Journal Title
  
  Forensic Imaging
  
  Volume: 20 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Toxoplasma encephalitis followed by primary EBV-associated post-transplant lymphoproliferative disorder of the central nervous system in a patient undergoing allogeneic hematopoietic stem cell transplant: a case report.2020
- Author(s)
  Azusa Mayumi, Takaya Yamashita, Ikuo Matsuda, Kenji Hikosaka, Satoshi Fujino, Kazumi Norose, Yasuyuki Kato, Seiichi Hirota, Toshiyuki Nakajima, Hiroyasu Ogawa , Kazuhiro Ikegame
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 52 Issue: 9 Pages: 2858-2860
- DOI
  10.1016/j.transproceed.2020.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07003, KAKENHI-PROJECT-19K07520
[Journal Article] Hypericum erectum alcoholic extract inhibits Toxoplasma growth and Entamoeba encystation: an exploratory study on the anti-protozoan potential.2020
- Author(s)
  Shinjyo N, Nakayama H, Ishimaru K, Hikosaka K, Mi-Ichi F, Norose K, Yoshida H.
- Journal Title
  
  J Nat Med
  
  Volume: 74 Issue: 1 Pages: 294-305
- DOI
  10.1007/s11418-019-01369-6
- NAID
  40022130373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-19K07839, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-17K15676, KAKENHI-PROJECT-19K07627, KAKENHI-PROJECT-18K07087, KAKENHI-PUBLICLY-18H04675
[Journal Article] Desensitization to trimethoprim-sulfamethoxazole in a toxoplasmic encephalitis patient who was intolerant to conventional treatments.2020
- Author(s)
  Miyata N, Yoshimura Y, Hikosaka K, Norose K, Tachikawa N.
- Journal Title
  
  J Infect Chemother
  
  Volume: 26 Issue: 3 Pages: 289-293
- DOI
  10.1016/j.jiac.2019.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-17KT0124
[Journal Article] Toxoplasmosis-associated central nervous system vasculitis accompanied by multiple cerebral hemorrhages developing subsequent to cord blood transplantation2019
- Author(s)
  太田貴徳, 今永博, 奥誠道, 楠元大岳, 杉尾康浩, 田宮貞史, 久保安孝, 小川亮介, 彦坂健児, 野呂瀬一美, 大野裕樹
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 2 Pages: 118-123
- DOI
  10.11406/rinketsu.60.118
- NAID
  130007607569
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-17KT0124
[Journal Article] Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign".2019
- Author(s)
  Ueno H, Norose K, Kamimura T, Mihara K, Yamasaki F, Hikosaka K, J Amatya V, Takeshima Y, Kurisu K, Maruyama H.
- Journal Title
  
  Intern Med
  
  Volume: 58 Pages: 1157-1162
- NAID
  130007632763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign"2019
- Author(s)
  Ueno H, Norose K, Kamimura T, Mihara K, Yamasaki F, Hikosaka K, J Amatya V, Takeshima Y, Kurisu K, Maruyama H
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 8 Pages: 1157-1162
- DOI
  10.2169/internalmedicine.1156-18
- NAID
  130007632763
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-04-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-16K10757
[Journal Article] Disseminated toxoplasmosis with atypical symptoms which developed with exacerbation of systemic lupus erythematosus.2019
- Author(s)
  Furuya H, Ikeda K, Iida K, Suzuki K, Furuta S, Tamachi T, Suzuki K, Miura G, Hiraguri M, Hase R, Hikosaka K, Norose K, Nakajima H
- Journal Title
  
  Lupus
  
  Volume: 28 Issue: 1 Pages: 133-136
- DOI
  10.1177/0961203318815583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0124
[Journal Article] The complete mitochondrial genome of Sarcoptes scabiei var. nyctereutis from the Japanese raccoon dog: Prediction and detection of two transfer RNAs (tRNA-A and tRNA-Y)2018
- Author(s)
  Ueda T, Tarui H, Kido N, Imaizumi K, Hikosaka K, Abe T, Minegishi D, Tada Y, Nakagawa M, Tanaka S, Omiya T, Morikaku K, Kawahara M, Kikuchi-Ueda T, Akuta T, Ono Y
- Journal Title
  
  Genomics
  
  Volume: - Issue: 6 Pages: 1183-1191
- DOI
  10.1016/j.ygeno.2018.09.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15676, KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-17KT0124
[Journal Article] Utility of the cytochrome c oxidase subunit I gene for the diagnosis of toxoplasmosis using PCR.2017
- Author(s)
  Feng X, Norose K, Li K, Hikosaka K.
- Journal Title
  
  J Microbiol Methods.
  
  Volume: 141 Pages: 82-86
- DOI
  10.1016/j.mimet.2017.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-17K15676
[Journal Article] Lactate retards the development of erythrocytic stages of the human malaria parasite Plasmodium falciparum.2015
- Author(s)
  Hikosaka K, Hirai M, Komatsuya K, Ono Y, Kita K.
- Journal Title
  
  Parasitol Int
  
  Volume: 64 Issue: 3 Pages: 301-303
- DOI
  10.1016/j.parint.2014.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26860277, KAKENHI-PROJECT-24590501
[Journal Article] Mitochondrial genome structure of the phylum Apicomplexa2015
- Author(s)
  Hikosaka K, Tanabe K, Kita K
- Journal Title
  
  Jpn J Protozool
  
  Volume: 48 Pages: 45-56
- NAID
  130005254780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860277
[Presentation] 潜在性トキソプラズマ症を合併した中枢神経浸潤Erdheim-Chester病の1例2023
- Author(s)
  和田山智哉，清水幹人，木村一皓，馬場孝輔，別宮豪一，長野清一，野呂瀬一美，彦坂健児，村山繁雄，望月秀樹
- Organizer
  第６４回神経病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] マラリア感染血液のモデル化の検討2022
- Author(s)
  横山大知、川嶋大介、Tran Anh Kiet、彦坂健児、Kennedy Okeyo、武居昌宏
- Organizer
  日本機械学会　関東支部第28期総会・講演会
- Data Source
  KAKENHI-PROJECT-20KK0251
[Presentation] Challenges in isolation of mitochondrial ribosomes from the malaria parasite2022
- Author(s)
  Xioxia Lin, Hirokazu Sakamoto, Rie Kubota, Yoh-Ichi Watanabe, Daniel Ken Inaoka, Naoaki Shinzawa, Kenji Hikosaka
- Organizer
  第92回日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-20K07461
[Presentation] ニワトリの赤血球を用いた模擬マラリア感染赤血球の EIS2022
- Author(s)
  横山大知、川嶋大介、彦坂健児、Kennedy Omondi Okeyo、武居昌宏
- Organizer
  混相流シンポジウム 2022
- Data Source
  KAKENHI-PROJECT-20KK0251
[Presentation] Oroxylin A, a compound extracted from Chinese medicinal herbs, suppresses Toxoplasma gondii proliferation2022
- Author(s)
  Ziyue Zhang, Hirokazu Sakamoto, Kazumi Norose, Kenji Hikosaka.
- Organizer
  第９１回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] 遠心分離機一体型 EIS によるラベルフリーマラリア感染赤血球の検出2022
- Author(s)
  横山大知、川嶋大介、Tran Anh Kiet、彦坂健児、Kennedy Okeyo、武居昌宏
- Organizer
  日本機会学会　第32回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-20KK0251
[Presentation] Growth of Toxoplasma gondii is inhibited by oroxylin A, a compound derived from traditional Chinese medicinal plants.2022
- Author(s)
  Ziyue Z Zhang, Hirokazu Sakamoto, Kazumi Norose, Kenji Hikosaka.
- Organizer
  第２８回分子寄生虫学ワークショップ
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] 複数回の肛囲検査では虫卵が検出されず, 虫体から診断に至った蟯虫症の一例2022
- Author(s)
  中川良太, 栗原恵理佳, 野呂瀬一美, 彦坂健児, 金澤正樹, 寺井勝
- Organizer
  第３３回日本臨床寄生虫学会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] A case of catastrophic disseminated toxoplasmosis mimicking late-onset VOD/SOS after unrelated PBSCT2022
- Author(s)
  Yosuke Makuuchi, Sayaka Tanaka, Hideo Koh, Makoto Niki, Kazumi Norose, Yosuke Nakaya, Masatomo Kuno, Naonori Harada, Teruhito Takakuwa, Hiroshi Okamura, Asao Hirose, Mika Nakamae, Mitsutaka Nishimoto, Yasuhiro Nakashima, Kenji Hikosaka, Hiroshi Kakeya, Masahiko Ohsawa, Masayuki Hino, Hirohisa Nakamae
- Organizer
  第８４回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] 酵母細胞質型ジヒドロオロト酸脱水素酵素遺伝子を導入したげっ歯類マラリア原虫のアトバコン耐性発現パターンの解析2022
- Author(s)
  陳雪、新倉保、坂本寛和、佐倉孝哉、稲岡ダニエル健、彦坂健児
- Organizer
  第92回日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-20K07461
[Presentation] ナイジェリアの家畜より分離した捻転胃虫の遺伝的多様性解析2021
- Author(s)
  カウエ　サイモン、バログン　エマニュエル、野呂瀬　一美、アデク　マイケル、彦坂　健児
- Organizer
  第９０回日本寄生虫学会　第３２回日本臨床寄生虫学会　合同大会
- Data Source
  KAKENHI-PROJECT-19K07839
[Presentation] ナイジェリアの家畜より分離した捻転胃虫の遺伝的多様性解析2021
- Author(s)
  カウエ　サイモン、バログン　エマニュエル、野呂瀬　一美、アデク　マイケル、彦坂　健児
- Organizer
  第９０回日本寄生虫学会　第３２回日本臨床寄生虫学会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] ナイジェリアの家畜より分離した捻転胃虫の遺伝的多様性解析2021
- Author(s)
  カウエ　サイモン、バログン　エマニュエル、野呂瀬　一美、アデク　マイケル、彦坂　健児
- Organizer
  第９０回日本寄生虫学会大会　第３２回日本臨床寄生虫学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] 早期診断・治療が成功した同種移植後トキソプラズマ脳炎の一例2021
- Author(s)
  岩田紫乃、原田介斗、鬼塚真仁、白岩佐和子、原隆二郎、青山泰之、豊崎誠子、町田真一郎、山元佳、彦坂健児、野呂瀬一美、丸山治彦、忽那賢志、氏家無限、小川吉明、川田浩志、安藤潔
- Organizer
  第８３回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] トキソプラズマ脳炎を合併した中枢神経浸潤Erdheim-Chester病の1例2020
- Author(s)
  和田山　智哉，清水　幹人，木村　一皓，馬場　孝輔，別宮　豪一，奥野　龍禎，長野　清一，森田　諒，中河　秀憲，白野　倫徳，後藤　哲志，野呂瀬　一美，彦坂　健児，村山　繁雄，望月　秀樹
- Organizer
  第117回日本神経学会近畿地方会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] 臍帯血移植後に多発性脳出血を来したトキソプラズマ関連中枢神経系血管炎2020
- Author(s)
  太田貴徳，楠元大岳，上野稔幸、上原康文、杉尾康浩，田宮貞史、彦坂健児，野呂瀬一美，大野裕樹
- Organizer
  第42回造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] 臍帯血移植後に多発性脳出血を来したトキソプラズマ関連中枢神経系血管炎2020
- Author(s)
  太田貴徳，楠元大岳，上野稔幸、上原康文、杉尾康浩，田宮貞史、彦坂健児，野呂瀬一美，大野裕樹
- Organizer
  第42回造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] PCR targeting the cytochrome c oxidase subunit 1 gene for clinical diagnosis of toxoplasmosis.2019
- Author(s)
  Hikosaka K, Feng X, Koyama Y, Norose K.
- Organizer
  4th Africa international biotechnology and biomedical conference, AIBBC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] Traditional Kampo formula (漢方) Scutellaria-Coptis is protective against Toxoplasma infection via synergistic immunomodulation2019
- Author(s)
  Noriko Shinjyo, Kenji Hikosaka, Hiroki Yoshida, Kazumi Norose
- Organizer
  第84回日本インターフェロンサイトカイン学会
- Data Source
  KAKENHI-PROJECT-19K07839
[Presentation] 多摩川河口域に飛来する野鳥の腸管寄生虫感染状況の解明2019
- Author(s)
  彦坂健児、田中咲帆、馮　雪、篠田渉平、LiLi、Li Kexin,　野呂瀬　一美
- Organizer
  第８８回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] Traditional Kampo formula (漢方) Scutellaria-Coptis (瀉心湯)is protective against Toxoplasma infection via synergistic immunomodulation.2019
- Author(s)
  Shinjyo N, Hikosaka K, Yoshida H, Norose K.
- Organizer
  第84回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] PCR targeting the cytochrome c oxidase subunit 1 gene for clinical diagnosis of toxoplasmosis.2019
- Author(s)
  Hikosaka K, Feng X, Koyama Y, Norose K.
- Organizer
  4th Africa international biotechnology and biomedical conference, AIBBC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] Traditional Kampo formula (漢方) Scutellaria-Coptis (瀉心湯)is protective against Toxoplasma infection via synergistic immunomodulation.2019
- Author(s)
  Shinjyo N, Hikosaka K, Yoshida H, Norose K
- Organizer
  第84回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07520
[Presentation] ディープシーケンスによるマラリア原虫のアトバコン耐性に関わる変異の解析2018
- Author(s)
  彦坂健児、馮雪、本間一、松崎素道、元岡大佑、中村昇太、野呂瀬一美、北潔
- Organizer
  第87回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17K15676
[Presentation] 自家末梢血幹細胞移植後に発症したトキソプラズマ症の検討－臨床所見およびST合剤予防投与の効果－2018
- Author(s)
  北原茉莉、廣島由紀、植松望武、數本弘子、宍戸努、貝梅紘子、桐原健彦、武田航、植木俊充、住昌彦、上野真由美、市川直明、彦坂健児、野呂瀬一美、小林光
- Organizer
  第40回　日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] ディープシーケンスによるマラリア原虫のアトバコン耐性に関わる点変異の解析2018
- Author(s)
  彦坂健児、馮　雪、本間　一、松崎素道、元岡大佑、中村昇太、野呂瀬一美、北　潔
- Organizer
  第87回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] 全身性エリテマトーデス(SLE)再燃時に播種性トキソプラズマ症の診断に至った一例2017
- Author(s)
  古矢裕樹、鈴木一正、彦坂健児、古田俊介、池田啓、中島裕史、野呂瀬一美
- Organizer
  第28回日本臨床寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] 眼トキソプラズマ症：マウスモデルにおける前房水中サイトカイン・ケモカイン解析―髄液および血清との比較2017
- Author(s)
  李　可きん、馮　雪、彦坂健児、野呂瀬一美
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] Sulfamethoxazole-Trimethoprim(ST合剤)の脱感作により治療を継続できたトキソプラズマ脳炎(TE)の一例2017
- Author(s)
  宮田順之、吉村幸浩、彦坂健児、野呂瀬一美、立川夏夫
- Organizer
  第31回日本AIDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] 法医解剖前CTにおいて小腸内に条虫の存在が示唆された無鉤条虫症の1例2017
- Author(s)
  星岡佑美、吉田真衣子、槇野陽介、彦坂健児、野呂瀬一美、岩瀬博太郎
- Organizer
  第28回日本臨床寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] シトクロムc酸化酵素サブユニット１遺伝子を標的としたPCRによる新規トキソプラズマ病診断法の検討2017
- Author(s)
  馮　雪、Kexin Li, 野呂瀬一美、彦坂健児
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17KT0124
[Presentation] マラリア原虫の遺伝子点変異によるアトバコン耐性獲得様式の解明2016
- Author(s)
  彦坂健児、本間一、松崎素道、野呂瀬一美、北潔
- Organizer
  第85回日本寄生虫学会大会
- Place of Presentation
  宮崎市民プラザ（宮崎県・宮崎市）
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-26860277
[Presentation] マラリア原虫の遺伝子点変異による薬剤耐性獲得様式の解明2015
- Author(s)
  彦坂健児、本間一、松崎素道、野呂瀬一美、北潔
- Organizer
  第23回分子寄生虫ワークショップ/第13回分子寄生虫・マラリア研究フォーラム合同大会
- Place of Presentation
  帯広畜産大学・原虫病研究センター　PKホール（北海道・帯広市）
- Year and Date
  2015-08-30
- Data Source
  KAKENHI-PROJECT-26860277
[Presentation] アピコンプレクサ原虫の多様なミトコンドリアゲノム構造
- Author(s)
  彦坂健児
- Organizer
  第47回日本原生生物学会大会
- Place of Presentation
  宮城
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-26860277

1. NOROSE Kazumi (30156244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 42 results
2. Shinjyo Noriko (60794039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 坂本寛和 (40724349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 佐藤守 (20401002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 野村文夫 (80164739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 関根章博 (30425631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 猪狩英俊 (50312947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 照屋勝治 (50505386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉田朝秀 (20363682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 前田卓哉 (20383763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中村ふくみ (90295204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉田裕樹 (40260715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 渡邊洋一 (90323568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 稲岡健ダニエル (10623803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 武居昌宏 (90277385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. オケヨケネディオモンディ (10634652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 川嶋大介 (10813785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. 平井誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 松田育雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 廣田誠一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 矢野寿一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 中野竜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 遠藤史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hikosaka Kenji 彦坂 健児

彦坂 健児 ヒコサカ ケンジ

Research Projects

Research Products

Co-Researchers

The role of DNA methylation in regulating dormancy mechanisms of Trichomonas vaginalisPrincipal Investigator

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A study on a low-cost translation mechanism in the mitochondrial ribosome of the malaria parasitePrincipal Investigator

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ラベルフリーで多重感染定量検出可能なCD型EISのケニアにおける検証研究

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Elucidation of molecular epidemiological information of Toxoplasma gondii using whole genome sequence and identification of pathogenicity-related genes

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Anti-Toxoplasma and neuroprotective potential of medicinal plant Hypericum

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Establishment of the detection method for the reactivation of toxoplasmosis and the evaluatiion method for the severity of toxoplasmosis by mass spectrometer

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A study towards establishing a cell line depleted of mitochondrial DNA in malaria parasitesPrincipal Investigator

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Mutation patterns of mitochondrial DNA in atovaquone-resistant malaria parasitesPrincipal Investigator

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[Book] An Overview of Tropical Diseases -Mitochondria of Malaria Parasites as A Drug Target2015

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[Book] An Overview of Tropical Diseases, Chapter 2, Mitochondria of malaria parasites as a drug target2015

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[Journal Article] Sinusoidal obstruction syndrome associated with disseminated toxoplasmosis involving the liver after allogeneic hematopoietic stem cell transplantation: A case report2023

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[Journal Article] Genetic relatedness of third-generation cephalosporin-resistant Escherichia coli among livestock, farmers, and patients in Japan2023

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[Journal Article] Development of a novel electroporation method for the oyster parasite Perkinsus marinus.2022

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[Journal Article] Siccanin is a dual-target inhibitor of Plasmodium falciparum mitochondrial complex II and complex III.2022

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Hikosaka Kenji 彦坂健児

彦坂健児ヒコサカケンジ

[Journal Article] 複数回の肛囲検査では虫卵が検出されず、虫体から診断に至った蟯虫症の一例2022