Sien Tadahiko 枝園忠彦

… Alternative Names

Shien Tadahiko 枝園忠彦

SHIEN Tadahiko 枝園忠彦

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Researcher Number	30509451
Other IDs	https://orcid.org/0000-0003-3202-5512
Affiliation (Current)	2025: 岡山大学, 医療開発領域, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 岡山大学, 大学病院, 教授 2021 – 2023: 岡山大学, 大学病院, 准教授 2022: 岡山大学, 大学病院, 講師 2020 – 2022: 岡山大学, 大学病院, 研究准教授 2019: 岡山大学, 大学病院, 講師 2010: 岡山大学, 岡山大学病院, 助教 2009 – 2010: Okayama University, 病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Laboratory medicine Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Medium-sized Section 50:Oncology and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 乳癌 / HER2 / TDM1 / 耐性化機序 / 薬剤耐性 / 耐性克服 / 耐性機序 / 分子標的治療 / HER2陽性 / 転移乳がん … More / 転移 / がん幹細胞 / 予後因子 / 幹細胞 … More Except Principal Investigator 乳癌 / Axillary reverse mapping / 支持療法 / 乳癌術後 / 腋窩リンパ節 / axillary reverse mapping / センチネルリンパ節 / リンパ浮腫 / ＣＤＫ４／６阻害薬 / GeoMx / 空間的遺伝子発現 / 説明可能な深層学習 / CDK4/6阻害薬 / 膵臓癌 / 卵巣癌 / 全エクソン解析 / 重複癌 / 重複がん / 人工知能 / 免疫染色 / AI / 病理診断 Less

Multicenter research for social implementation of highly accurate and rapid Artificial intelligence pathological diagnosis system
- Principal Investigator
  
  寺田かおり
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Akita University
BRCA関連重複癌患者の全エクソン解析を通じた新規癌発症リスク因子の同定
- Principal Investigator
  
  谷岡真樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
耐性化機序に基づいたHER2陽性乳癌に対する治療戦略の開発Principal Investigator
- Principal Investigator
  
  枝園忠彦
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University
Japan-U.S. collaboration to find novel biomarkers of CDK4/6 inhibitor using explainable deep learning and spatial genetic analysis.
- Principal Investigator
  
  谷岡真樹
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Okayama University
上肢リンパ地図がもたらす乳がん術後リンパ浮腫予防
- Principal Investigator
  
  木股敬裕
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Okayama University
Treatment strategy overcoming HER2 targetted drug resistancePrincipal Investigator
- Principal Investigator
  
  Shien Tadahiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Okayama University
The efficacy of identifying the stem cell to decide the breast cancer treatment strategy.Principal Investigator
- Principal Investigator
  
  SHIEN Tadahiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University

All 2023 2021 2020 2011 2010

All Journal Article Presentation

[Journal Article] YES1 as a Therapeutic Target for HER2-Positive Breast Cancer after Trastuzumab and Trastuzumab-Emtansine (T-DM1) Resistance Development2021
- Author(s)
  Fujihara Miwa、Shien Tadahiko、Shien Kazuhiko、Suzawa Ken、Takeda Tatsuaki、Zhu Yidan、Mamori Tomoka、Otani Yusuke、Yoshioka Ryo、Uno Maya、Suzuki Yoko、Abe Yuko、Hatono Minami、Tsukioki Takahiro、Takahashi Yuko、Kochi Mariko、Iwamoto Takayuki、Taira Naruto、Doihara Hiroyoshi、Toyooka Shinichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 12809-12809
- DOI
  10.3390/ijms222312809
- NAID
  120007183232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09070
[Journal Article] YES1 activation induces acquired resistance to neratinib in HER2 ‐amplified breast and lung cancers2020
- Author(s)
  Takeda Tatsuaki、Yamamoto Hiromasa、Suzawa Ken、Tomida Shuta、Miyauchi Shunsaku、Araki Kota、Nakata Kentaro、Miura Akihiro、Namba Kei、Shien Kazuhiko、Soh Junichi、Shien Tadahiko、Kitamura Yoshihisa、Sendo Toshiaki、Toyooka Shinichi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 849-856
- DOI
  10.1111/cas.14289
- NAID
  120006839439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09070, KAKENHI-PROJECT-19K09285, KAKENHI-PROJECT-17K10784
[Presentation] CDK4/6阻害薬の有害事象中止に関する年齢の影響についての検討2023
- Author(s)
  仁科卓也、谷岡真樹、高田健二、突沖貴宏、高橋侑子、岩本高行、岩谷胤生、枝園忠彦
- Organizer
  日本乳癌学会
- Data Source
  KAKENHI-PROJECT-22KK0118
[Presentation] Prognostic impact of discordance of biological markers between primary and metastatic breast cancer tissue from autopsy.2011
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  International Conference on Primary Therapy of Early breast Cancer 2011.
- Place of Presentation
  スイスザンクトガレン
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] Prognostic impact of discordance of biological markers between primary and metastatic breast cancer tissue from autopsy.2011
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  International Conference on Primary Therapy of Early breast Cancer 2011
- Place of Presentation
  St.Gallen,スイス
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] Clinical features of surgical resection for solitary pulmonary metastasis and the discrepancy in immunopathological features between primary and metastatic breast cancer lesions2010
- Author(s)
  枝園忠彦
- Organizer
  San Antonio Breast Cancer Symposium 2010
- Place of Presentation
  アメリカサンアントニオ
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] 乳癌ALDH1陽性腋窩リンパ節転移と予後の相関2010
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  第18回日本乳癌学会学術総会
- Place of Presentation
  北海道
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] 乳癌肺転移に対する切除例の検討2010
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  第7回日本乳癌学会中国四国地方会
- Place of Presentation
  高知県高知市
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] Expression of ALDH1 in the axillary lumph node metastases is a predictor of poor clinical outcome in breast cancer patients.2010
- Author(s)
  野上智弘, 枝園忠彦
- Organizer
  ASCO Breast Cancer Symposium 2010
- Place of Presentation
  アメリカワシントンDC
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] 乳癌肺転移に対する切除例の検討2010
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  第7回日本乳癌学会中国四国地方会
- Place of Presentation
  高知
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] 乳癌ALDH1陽性腋窩リンパ節転移と予後の相関2010
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  第18回日本乳癌学会学術総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] Expression of ALDH1 in the axillary lumph node metastases is a predictor of poor clinical outcome in breast cancer patients.2010
- Author(s)
  野上智弘、枝園忠彦
- Organizer
  ASCO Breast Cancer Symposium 2010
- Place of Presentation
  Washington DC,アメリカ
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21790536
[Presentation] Clinical features of surgical resection for solitary pulmonary metastasis and the discrepancy in immunopathological features between primary and metastatic breast cancer lesions2010
- Author(s)
  枝園忠彦
- Organizer
  SanAntonio Breast Cancer Symposium 2010
- Place of Presentation
  SanAntonio,アメリカ
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790536

1. 豊岡伸一 (30397880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 諏澤憲 (90839713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 谷岡真樹 (60573045)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 柳井広之 (90379735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 山本寛斉 (40467733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 寺田かおり (60610748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 九冨五郎 (10404625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 南谷佳弘 (30239321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石飛真人 (40443535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 南條博 (70250892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 近藤直人 (90529166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 中村圭一郎 (90359886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 枝園和彦 (30708079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 遠西大輔 (20825096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宮内翔子 (40828555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 諸岡健一 (80323806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 木股敬裕 (50392345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 品岡玲 (90724500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 濱田龍正 (40933362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小阪美津子 (50270476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sien Tadahiko 枝園 忠彦

Shien Tadahiko 枝園 忠彦

SHIEN Tadahiko 枝園 忠彦

Research Projects

Research Products

Co-Researchers

Multicenter research for social implementation of highly accurate and rapid Artificial intelligence pathological diagnosis system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

BRCA関連重複癌患者の全エクソン解析を通じた新規癌発症リスク因子の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

耐性化機序に基づいたHER2陽性乳癌に対する治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Japan-U.S. collaboration to find novel biomarkers of CDK4/6 inhibitor using explainable deep learning and spatial genetic analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

上肢リンパ地図がもたらす乳がん術後リンパ浮腫予防

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment strategy overcoming HER2 targetted drug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The efficacy of identifying the stem cell to decide the breast cancer treatment strategy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] YES1 as a Therapeutic Target for HER2-Positive Breast Cancer after Trastuzumab and Trastuzumab-Emtansine (T-DM1) Resistance Development2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] YES1 activation induces acquired resistance to neratinib in HER2 ‐amplified breast and lung cancers2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] CDK4/6阻害薬の有害事象中止に関する年齢の影響についての検討2023

Author(s)

Organizer

Data Source

[Presentation] Prognostic impact of discordance of biological markers between primary and metastatic breast cancer tissue from autopsy.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Prognostic impact of discordance of biological markers between primary and metastatic breast cancer tissue from autopsy.2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Clinical features of surgical resection for solitary pulmonary metastasis and the discrepancy in immunopathological features between primary and metastatic breast cancer lesions2010

Author(s)

Organizer

Place of Presentation

Sien Tadahiko 枝園忠彦

Shien Tadahiko 枝園忠彦

SHIEN Tadahiko 枝園忠彦