Kodama Masami 児玉昌美

Researcher Number	30512248
Other IDs
Affiliation (Current)	2022: 順天堂大学, 医学部, 非常勤助教
Affiliation (based on the past Project Information) *help	2021 – 2022: 順天堂大学, 医学部, 非常勤助教 2018 – 2020: 東京大学, 定量生命科学研究所, 特任研究員 2017 – 2018: 東京医科歯科大学, 難治疾患研究所, 非常勤講師 2016: 東京医科歯科大学, 難治疾患研究所, 日本学術振興会特別研究員 2015: 東京医科歯科大学, 難治疾患研究所, その他
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 43020:Structural biochemistry-related Except Principal Investigator General pharmacology / Basic Section 43020:Structural biochemistry-related
Keywords	Principal Investigator イオンチャネル / 心筋細胞 / 心筋 / 分子間相互作用 / カリウムチャネル / 分子複合体 / GCase受容体 Except Principal Investigator イオンチャネル / 薬理学 / 不整脈 … More / 心不全 / iPS細胞 / シミュレーション / ヒトiPS細胞 / インシリコモデル / 統合的解析 / 不整脈トリガー / 生理学 / 薬学 / 循環器・高血圧 / 心臓安全性 / 画像処理 / 抗がん剤 / 循環器･高血圧 / 膜蛋白質 / リアノジン受容体 / カルシウムチャネル / クライオ電子顕微鏡 Less

Structural analysis of the gating mechanism of cardiac ryanodine receptor
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
GCase受容体の構造生物学ーリガンドの認識機構と結合シグナルの分子内伝達機構Principal Investigator
- Principal Investigator
  
  児玉昌美
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Juntendo University
Roles of molecular complex of IKs channel in plasma membrane depolarization - relaxation coupling in cardiac myocytesPrincipal Investigator
- Principal Investigator
  
  Kodama Masami
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  The University of Tokyo
Multidisciplinary approach to cardiac arrhythmogenesis assessment during drug discovery
- Principal Investigator
  
  Kurokawa Junko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  University of Shizuoka
  Tokyo Medical and Dental University

All 2021 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs2018
- Author(s)
  Li, M., Kanda, Y., Ashihara, T., Sasano, T., Nakai, Y., Kodama, M., Hayashi, E., Sekino, Y., Furukawa, T., and Kurokawa, J.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 134 Pages: 75-85
- DOI
  10.1016/j.jphs.2017.05.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07726, KAKENHI-PROJECT-16K09431, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-26293052, KAKENHI-PROJECT-16H05238
[Journal Article] A risk assessment of a common drug using xenograft model.2017
- Author(s)
  Kodama M, Kurokawa J
- Journal Title
  
  Annals of Trans Med.
  
  Volume: 5 Pages: 88-88
- DOI
  10.21037/atm.2017.01.59
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-14J40079
[Journal Article] Efficient Large-Scale 2D Culture System for Human Induced Pluripotent Stem Cells and Differentiated Cardiomyocytes.2017
- Author(s)
  Toyama S, Fujita J*, Fujita C, Yamaguchi M, Kanaami S, Ohno R, Sakamoto K, Kodama M, Kurokawa J, Kanazawa H, Seki T, Kishino Y, Okada M, Nakajima K, Tanosaki S, Someya S, Hirano A, Kawaguchi S, Kobayashi E, Fukuda K
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 9 Pages: 1406-1414
- DOI
  10.1016/j.stemcr.2017.08.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-17H05067, KAKENHI-PROJECT-15K09098
[Journal Article] Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes.2016
- Author(s)
  Kurokawa J, Kodama M, Clancy CE and Furukawa T
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 168 Pages: 23-28
- DOI
  10.1016/j.pharmthera.2016.09.004
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-14J40079
[Journal Article] Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters.2015
- Author(s)
  Kurokawa, J., Sasano, T., Kodama, M., Li, M., Ebana, Y., Harada, N., Honda, S.-I., Nakaya, H., & Furukawa, T.
- Journal Title
  
  Journal of Toxicological Science
  
  Volume: 40 Pages: 339-348
- DOI
  10.2131/jts.40.339
- NAID
  130005068413
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461398, KAKENHI-PROJECT-26460334, KAKENHI-PROJECT-15K15049, KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-14J40079, KAKENHI-PROJECT-26293052
[Presentation] 心筋KCNQ1チャネル分子複合体の病態生理学的意義に関する研究2021
- Author(s)
  稲田理毅、児玉昌美，山崎泰広, 坂本多穗, 黒川洵子
- Organizer
  日本薬学会　第141年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06683
[Presentation] Roles of macromolecular complexes in calcium-sensitivity of the cardiac IKs channel.2019
- Author(s)
  Sae Kimura, Masami Kodama, Shushi Nagamori, Takahiro Iwamoto, Satomi Kita, and Junko Kurokawa.
- Organizer
  第92回日本薬理学会年会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06683
[Presentation] Development of a novel functional assay to evaluate cardiac toxicity using human iPS cell-derived cardiomyocytes.2018
- Author(s)
  Yui Suzuki, Yusuke Sano, Momoka Nakagawa, Masami Kodama, Yasunari Kanda, Masahiko Yamaguchi, Kazuho Sakamoto, Junko Kurokawa
- Organizer
  The 4th International Conference on Pharma and Food
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] フィールドモーションイメージングによるマウス心筋の力学的機能の解析2018
- Author(s)
  佐野優介、鈴木結衣、山口賢彦、児玉昌美、古川哲史、坂本多穗、黒川洵子
- Organizer
  第28回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] A multidisciplinary approach for pharmacological assessment using human iPS-derived cardiomyocytes.2018
- Author(s)
  Kurokawa J, Kodama M, Kanda Y, Ashihara T, Nagamori S, Suzuki Y, Sakatoku K,Iwasaki N, Sano Y, Sakamoto K
- Organizer
  WCP2018 KYOTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] 心筋IKsチャネルのCa2+感受性における分子複合体の役割2017
- Author(s)
  福田俊，児玉昌美，永森收志，五十棲規嘉，藤塚美紀，喜多紗斗美，岩本隆宏，金井好克，古川哲史，黒川洵子
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] セルモーションイメージングを用いたヒトiPS細胞由来心筋細胞における心臓部位特異的な薬効評価2017
- Author(s)
  鈴木結衣, 高橋健太郎,児玉昌美, 諌田泰成, 山口賢彦, 早川智広, 松井恵理子, 古川哲史, 黒川洵子
- Organizer
  第8回日本安全性薬理研究会
- Place of Presentation
  東京大学農学部弥生講堂
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] セルモーションイメージングによるヒトiPS細胞由来心筋細胞を用いた薬効評価技術の基盤構築2017
- Author(s)
  鈴木結衣、高橋健太郎、児玉昌美、諫田泰成、山口賢彦、早川智広、松居恵理子、古川哲史、黒川洵子
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] ヒトiPS細胞とセルモーションイメージングを用いた心臓部位特異的な薬効評価法の基盤技術の開発.2017
- Author(s)
  鈴木結衣, 高橋健太郎,児玉昌美, 諌田泰成, 山口賢彦, 早川智広, 松井恵理子, 古川哲史, 黒川洵子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] An origin of sex differences in coronary arteries of embryonic mice.2017
- Author(s)
  Yamaguchi M, Kodama M, Okuno R, Arima Y, Nishiyama K, Kurihara H, Kurokawa J:
- Organizer
  8th Congress of the International Society for Gender Medicine
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] セルモーションイメージングによるマウス心筋の力学的機能の解析2017
- Author(s)
  佐野優介、鈴木結衣、髙橋健太郎、児玉昌美、山口賢彦、笹野哲郎、早川智宏、松居恵理子、古川哲史、黒川洵子
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] セルモーションイメージングとヒトiPS細胞由来心筋細胞を用いた抗がん剤の慢性毒性評価2017
- Author(s)
  酒徳航平、児玉昌美、諫田泰成、山崎泰広、関野祐子、黒川洵子
- Organizer
  第8回日本安全性薬理研究会
- Place of Presentation
  東京大学農学部弥生講堂
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] 心筋遅延整流性カリウムチャネルとカルシウムシグナリング分子複合体の解析2017
- Author(s)
  児玉昌美、木村麗子、酒德航平、岩崎菜々美、古谷和春、永森收志、芦原貴司、古川哲史、関野祐子、諫田泰成、黒川洵子
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] 遅延整流性カリウムチャネルのカルシウム感受性における分子複合体形成の役割.2017
- Author(s)
  児玉昌美，福田俊，永森收志，五十棲規嘉、藤塚美紀，金井好克，古川哲史，黒川洵子
- Organizer
  第94回日本生理学会年会
- Place of Presentation
  浜松アクトシティ
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] MVP法を用いたヒトiPS細胞由来分化心筋細胞の心臓部位特異的な薬効評価技術の開発2017
- Author(s)
  鈴木結衣、佐野優介、高橋健太郎、児玉昌美、諫田泰成、山口賢彦、古川哲史、黒川洵子
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] KCNQ1チャネル分子複合体による多彩な細胞シグナル応答2016
- Author(s)
  黒川洵子、児玉昌美、永森收志、福田俊、金井好克、古川哲史
- Organizer
  平成28年度生理研研究会「生体界面研究会」
- Place of Presentation
  愛知、生理研研究所
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] トランスジェニックマウスを利用した心筋IKsチャネル分子複合体の網羅的解析2016
- Author(s)
  福田俊，児玉昌美，永森收志，五十棲規嘉、藤塚美紀，金井好克，古川哲史，黒川洵子
- Organizer
  第89回日本薬理学会大会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] Effects of anticancer drugs on contractile behaviors of human-induced pluripotent stem cell-derived cardiomyocyte monolayers evaluated with an image-based analysis using motion field imaging technique.2016
- Author(s)
  Kurokawa J, Kanda Y, Kodama M, Sekino Y, Furukawa T
- Organizer
  2016 SPS/JSPS/CSPT合同年会
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] ヒトiPS由来心筋細胞の動きベクトル解析による抗がん剤心毒性の評価法2016
- Author(s)
  黒川洵子、児玉昌美、高橋健太郎、諫田泰成、古川哲史
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  長野、信州大学医学部
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] 胎生マウスの冠血管形状に見られる性差2016
- Author(s)
  児玉昌美、古川哲史、黒川洵子
- Organizer
  第89回日本薬理学会大会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] The origin of sex differences in morphology of embryonic murine coronary arteries.2016
- Author(s)
  Kodama M, Furukawa T, and Kurokawa J.
- Organizer
  International and Interdisciplinary Symposium 2016.
- Place of Presentation
  東京、東京医科歯科大学
- Year and Date
  2016-07-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] ヒトiPS細胞由来心筋の活動電位形成に関連する遺伝子の定量的発現解析におけるリファレンス遺伝子の選定2016
- Author(s)
  木村麗子、児玉昌美、古谷和春、諫田泰成、倉智嘉久、関野祐子、古川哲史、黒川洵子
- Organizer
  第89回日本薬理学会大会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] トランスジェニックマウスを利用した心筋遅延整流性カリウムチャネル分子複合体の探索と解析2016
- Author(s)
  福田俊、児玉昌美、永森收志，五十棲規嘉、藤塚美紀，金井好克，古川哲史，黒川洵子
- Organizer
  第134回日本薬理学会関東部会
- Place of Presentation
  国際医療福祉大学、栃木
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] Regulation of cardiac L-type Ca2+ channel via a progesterone receptor.2016
- Author(s)
  Kurokawa J, Kodama M, Furukawa T
- Organizer
  第９回国際NO学会
- Place of Presentation
  仙台、仙台国際センター
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] ペーシング可能なヒトiPS細胞由来心筋高密度培養標本を用いたドキソルビシンの作用解析.2015
- Author(s)
  林英里奈、福田俊、児玉昌美、安東朋子、木村麗子、中井雄治、永森收志、金井好克、古川哲史、黒川洵子
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日大薬学部，習志野
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] 心筋Kv7.1チャネル分子複合体による多彩な細胞シグナル応答2015
- Author(s)
  黒川洵子、児玉昌美、永森收志，金井好克、古川哲史
- Organizer
  平成26年度生理学研究所研究会
- Place of Presentation
  岡崎、生理学研究所
- Year and Date
  2015-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] マウス冠血管形成における性差の起源の探索2015
- Author(s)
  児玉昌美、古川哲史、黒川洵子
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド，神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15H04684
[Presentation] ヒトカリウムチャネル遺伝子導入によるヒトiPS細胞由来心筋細胞の成熟化のメカニズム－発現レベルからの考察．2015
- Author(s)
  児玉昌美、李敏、芦原貴司、諫田泰成、関野祐子、古川哲史、黒川洵子
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日大薬学部，習志野
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-15H04684

1. Kurokawa Junko (40396982)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
2. 小川治夫 (40292726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 諫田泰成 (70510387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 芦原貴司 (80396259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 村山尚 (10230012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 呉林なごみ (50133335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小林琢也 (60468585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Okada Junichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Nakai Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. SASANO Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 林秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 古川哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 井原健介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 原田信広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 中谷晴昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 遠山周吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 福田恵一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤田淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 金澤英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 福田淳二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kodama Masami 児玉 昌美

Research Projects

Research Products

Co-Researchers

Structural analysis of the gating mechanism of cardiac ryanodine receptor

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

GCase受容体の構造生物学ーリガンドの認識機構と結合シグナルの分子内伝達機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of molecular complex of IKs channel in plasma membrane depolarization - relaxation coupling in cardiac myocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multidisciplinary approach to cardiac arrhythmogenesis assessment during drug discovery

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A risk assessment of a common drug using xenograft model.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient Large-Scale 2D Culture System for Human Induced Pluripotent Stem Cells and Differentiated Cardiomyocytes.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes.2016

Author(s)

Journal Title

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[Journal Article] Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters.2015

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[Presentation] 心筋KCNQ1チャネル分子複合体の病態生理学的意義に関する研究2021

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[Presentation] Roles of macromolecular complexes in calcium-sensitivity of the cardiac IKs channel.2019

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[Presentation] Development of a novel functional assay to evaluate cardiac toxicity using human iPS cell-derived cardiomyocytes.2018

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[Presentation] フィールドモーションイメージングによるマウス心筋の力学的機能の解析2018

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[Presentation] A multidisciplinary approach for pharmacological assessment using human iPS-derived cardiomyocytes.2018

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[Presentation] 心筋IKsチャネルのCa2+感受性における分子複合体の役割2017

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[Presentation] セルモーションイメージングを用いたヒトiPS細胞由来心筋細胞における心臓部位特異的な薬効評価2017

Kodama Masami 児玉昌美