KUREBAYASHI Nagomi 呉林なごみ

… Alternative Names

KUREBAYASHI Kunihiro 國廣なごみ

国廣なごみクニヒロナゴミ

KUNIHIRO-KUREBAYASHI Nag 国広なごみ

呉林なごみクレバヤシナゴミ

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Researcher Number	50133335
Other IDs	https://orcid.org/0000-0002-5005-9698
External Links
Affiliation (Current)	2025: 順天堂大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 順天堂大学, 医学部, 客員准教授 2019 – 2020: 順天堂大学, 医学部, 非常勤講師 2016 – 2019: 順天堂大学, 医学部, 先任准教授 2011 – 2015: 順天堂大学, 医学部, 准教授 2013: 順天堂大学, 医学部, 教授 … More 2007: Juuntendo University School of Medicine, Department of Pharmacology, Associate Professor 2005 – 2006: 順天堂大学, 医学部, 助教授 1999 – 2003: 順天堂大学, 医学部, 助教授 1998: 順天堂大学, 医学部, 講師 1987 – 1989: 順天堂大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 47040:Pharmacology-related / General pharmacology / Complex systems Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Basic Section 48020:Physiology-related / Basic Section 59020:Sports sciences-related / General pharmacology / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 56050:Otorhinolaryngology-related … More / Basic Section 43020:Structural biochemistry-related / Integrative animal science / General pharmacology / Neurophysiology and muscle physiology / Legal medicine / Neurophysiology and muscle physiology Less
Keywords	Principal Investigator カルシウム / 不整脈 / 心臓 / 心筋 / 抗不整脈薬 / 筋小胞体 / リアノジン受容体 / 心不全 / ライブイメージング / 2型リアノジン受容体 … More / Alternans / Na^+ / TRPV6 / Ca^<2+> / ATPase / カテコラミン誘発性多型性心室頻拍 / 拡張型心筋症 / 活動電位 / 創薬 / 機能抑制型変異 / 大規模スクリーニング / 細胞内カルシウム動態 / モデルマウス / RyR2阻害薬 / ハイスループットスクリーニング / ドラッグスクリーニング / RyR2 / CPVT / Atrial fibrillation / Calcium ion / Action potentia / Abnormal conductance / Connexin / Ca^<2+> overload / Arrhythmia / alternans / Ca^2+オーバロード / 心房細動 / 伝導障害 / コネキシン / Ca^<2+>オーバーロード / econazole / Ca^<2+> exchanger / dihydropyridine receptor / laser scanning confocal microscope / store-operated Ca^<2+> entry / skeletal muscle / cardiac muscle / 乳頭筋 / 心室性不整脈 / Ca過負荷 / Ca^<2+> exchange / ECaC / Ca^<2+> wave / エバネッセント顕微鏡 / calcium overload / Ca^<2+>流入 / エコナゾール / Ca^<2+>交換体 / ジヒドロピリジン受容体 / 共焦点顕微鏡 / ストア依存性Ca^<2+>流入 / 骨格筋 / sarcoplasmic reticulum / heart failure / Energy consumption / skinned fiber / heart / カフェイン / Ca^<2+>によるCa^<2+>遊離 / Mg^<2+> / エネルギー消費 / スキンドファイバー / Ca2+インジケータ / 形態解析 / 興奮伝導 / 電流 / イメージング / Ca2+遊離 / 睡眠時無呼吸症候群 / 組織イメージング / 筋節長 / 等尺性張力 / ミオシンATPase / カルシウム感受性 / エネルギ-転換機構 / スキンファイバ- … More Except Principal Investigator リアノジン受容体 / 筋小胞体 / 心不全 / カルシウムチャネル / 骨格筋 / イメージング / 心室性不整脈 / カルシウムイオン / 不整脈 / 興奮収縮連関 / 拡張型心筋症 / 運動療法 / クライオ電子顕微鏡 / イオンチャネル / 構造解析 / 筋収縮 / 粘弾性 / 微小管 / 小胞体 / 相互作用 / カルシウム遊離チャネル / マウスモデル / 老化 / カルシウム / 加齢性難聴 / 膜蛋白質 / レニン・アンギオテンシン阻害薬 / 機能解析 / 創薬 / 悪性高熱症 / サブタイプ / 筋挫傷 / 衝撃耐性 / 遺伝子 / 疾患モデル / 臨床心臓学 / マウス / 遺伝性 / 突然死 / Caffeine / Calmodulin Antagonists / Trifluoperazine / Ca^<2+> Sensitivity / ATPase Activity / Tension / Skinned Fiber / カルモジュリン阻害薬 / メリチン / W-7 / クロルプロマジン / スキンドファイバー / カフェイン / カルモデュリン拮抗剤 / トリフルオペラジン / Ca^<2+>感受性 / ATPase活性 / 張力 / スキンドファイバ- / sarcoplasmic reticulum / calcium ion / ryanodine receptor / heart failure / cardiac hypertrophy / 細胞内Ca2+ / カルモジュリン / 細胞内カルシウム / 心肥大 / リガンド結合 / ドメイン / Ca-ATPase / S4-S5リンカー / 人工アミノ酸 / 迷走神経 / ノックインマウス / 抗不安薬 / 抗うつ薬 / 遺伝的要因 / トリプトファン / セロトニン / 脳 / 不安障害 / うつ病 / うっ血性心不全 / β-アドレナリン受容体 / ユビキチン化 / 低酸素 / 認知機能障害 / 歯学 / 性差医学 / 心機能障害 / 間歇的低酸素 / 閉経 / 虚血 / 加齢 / 高血圧 / 間歇低酸素 / アルギナーゼ / 一酸化窒素 / オートファジー / 肺高血圧 / 間歇低酸素暴露 / 睡眠時無呼吸症候群 / 悪性高熱 Less

創薬へ向けた心筋型リアノジン受容体の活性制御機構の構造的解明
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
家族性拡張型心筋症モデルにおける運動療法の効果
- Principal Investigator
  
  杉原匡美
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
骨格筋のしなやかさにおける微小管の役割
- Principal Investigator
  
  小林琢也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Juntendo University
Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agentsPrincipal Investigator
- Principal Investigator
  
  呉林なごみ
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
Role of long-term cellular dysfunction due to abnormal Ca2+ metabolism in presbyopia
- Principal Investigator
  
  野島愛来
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Juntendo University
Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system
- Principal Investigator
  
  村山尚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
The construction of exercise therapy in familial DCM model mice
- Principal Investigator
  
  杉原匡美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Juntendo University
Structural analysis of the gating mechanism of cardiac ryanodine receptor
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
Role of Microtubules in the Muscle Structure-Contraction Relationship
- Principal Investigator
  
  Kobayashi Takuya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Juntendo University
Effectiveness of RyR2 inhibitors as antiarrhytmic drugsPrincipal Investigator
- Principal Investigator
  
  Kurebayashi Nagomi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators
- Principal Investigator
  
  Murayama Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
Elucidation of molecular mechanisms of spontaneous sudden cardiac death model mouse due to ventricular arrhythmia
- Principal Investigator
  
  Aonuma Kazutaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Integrative animal science
- Research Institution
  University of Tsukuba
Establishment of analysis method of ryanodine receptor arrhythmogenic mutations and its application to therapeutic drug screeningPrincipal Investigator
- Principal Investigator
  
  Kurebayashi Nagomi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
興奮伝導・不整脈発生における心筋組織の細胞間不均一性の関与Principal Investigator
- Principal Investigator
  
  呉林なごみ
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Juntendo University
Elucidation of regulatory mechanisms of type 2 ryanodine receptors by introducing artificial amino acids
- Principal Investigator
  
  MURAYAMA Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
Exploration of anti-arrhythmic drugs acting on RyR2 using myocardium and cultured cells.Principal Investigator
- Principal Investigator
  
  KUREBAYASHI Nagomi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
心臓組織ライブイメージングを利用した動物モデルの不整脈発生メカニズムの包括的解析Principal Investigator
- Principal Investigator
  
  呉林なごみ
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Juntendo University
Study on sudden cardiovascular death in animal model of sleep apnea syndrome
- Principal Investigator
  
  YOSHIDA Ken-ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo
Pathogenic mechanism of congestive heart failure in a mouse model of dilated cardiomyopathy with brain serotonin dysfunction
- Principal Investigator
  
  MORIMOTO Sachio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kyushu University
Regulation of ryanodine receptor channel by interdomain interaction
- Principal Investigator
  
  MURAYAMA Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Juntendo University
An experimental study for the mechanism of atrial fibrillation and its control by means of optical imaging of cell-to-cell communicationPrincipal Investigator
- Principal Investigator
  
  KUREBAYASHI Nagomi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
Molecular mechanisms underlying abnormal functions in RyR2 complex in cardiac hypertrophy/heart failure
- Principal Investigator
  
  MURAYAMA Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
IDENTIFICATION OF NON-VOLTAGE DEPENDENT CA^<2+> INFLUX PATHWAY IN CARDIAC MUSCLE AND ITS REGULATORY MECHANISM -Analysis by observation of subcellular Ca^<2+> dynamics using evanescent-field fluorescence microscopy-Principal Investigator
- Principal Investigator
  
  KUREBAYASHI Nagomi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
TITLE OF PROJECT : Effects of Drugs Used in Heart Failure on Energy Consumption of Loaded and Unloaded Cardiac Muscles.Principal Investigator
- Principal Investigator
  
  KUREBAYASHI Kunihiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  JUNTENDO UNIVERSITY
骨格筋スキンドファイバ-における化学的・力学的反応のカップリングの調節機構Principal Investigator
- Principal Investigator
  
  国広なごみ (呉林なごみ)
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
筋小胞体Ca^<2+>-ATPase蛋白のドメイン間相互作用
- Principal Investigator
  
  小川靖男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Increase by drugs in Ca^<2+> sensitivity of myofibrils
- Principal Investigator
  
  OGAWA Yasuo
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University

[Book] 不整脈学2012
- Author(s)
  呉林　なごみ
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24590331
[Book] 不整脈学2012
- Author(s)
  呉林なごみ
- Publisher
  南江堂
- Data Source
  KAKENHI-PUBLICLY-23136514
[Book] "Encyclopedia of Molecular Pharmacology"Ryanodine receptor2008
- Author(s)
  Murayama T, Kurebayashi N, Ogawa Y
- Publisher
  Springer,Berlin
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Screening for Novel Type 2 Ryanodine Receptor Inhibitors by Endoplasmic Reticulum Ca<sup>2+</sup>Monitoring2023
- Author(s)
  Takenaka Mai、Kodama Masami、Murayama Takashi、Ishigami-Yuasa Mari、Mori Shuichi、Ishida Ryosuke、Suzuki Junji、Kanemaru Kazunori、Sugihara Masami、Iino Masamitsu、Miura Aya、Nishio Hajime、Morimoto Sachio、Kagechika Hiroyuki、Sakurai Takashi、Kurebayashi Nagomi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 104 Issue: 6 Pages: 275-286
- DOI
  10.1124/molpharm.123.000720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652
[Journal Article] Drug development for the treatment of RyR1-related skeletal muscle diseases2023
- Author(s)
  Takashi Murayama, Nagomi Kurebayashi, Ryosuke Ishida, Hiroyuki Kagechika
- Journal Title
  
  Current Opinion in Pharmacology
  
  Volume: 69 Pages: 102356-102356
- DOI
  10.1016/j.coph.2023.102356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15244, KAKENHI-PROJECT-22K06652
[Journal Article] A potent and selective cis-amide inhibitor of ryanodine receptor 2 as a candidate for cardiac arrhythmia treatment2023
- Author(s)
  Ishida Ryosuke、Kurebayashi Nagomi、Iinuma Hiroto、Zeng Xi、Mori Shuichi、Kodama Masami、Murayama Takashi、Masuno Hiroyuki、Takeda Fumi、Kawahata Masatoshi、Tanatani Aya、Miura Aya、Nishio Hajime、Sakurai Takashi、Kagechika Hiroyuki
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 262 Pages: 115910-115910
- DOI
  10.1016/j.ejmech.2023.115910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K15244
[Journal Article] Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.2023
- Author(s)
  Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, Manabe H, Nakau K, Wada T, Kato K, Toyoda F, Yoshida Y, Makita N, Woltjen K, Ohno S, Kurebayashi N, Murayama T, Sakurai T, Horie M, Kimura T.
- Journal Title
  
  Circulation: Arrhythmia and Electrophysiology
  
  Volume: 16 Issue: 3 Pages: 9999-9999
- DOI
  10.1161/circep.122.011387
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-21K06781, KAKENHI-PROJECT-22K08179, KAKENHI-PROJECT-20K17113, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02920
[Journal Article] Involvement of kallikrein‐PAR2‐proinflammatory pathway in severe trastuzumab‐induced cardiotoxicity2022
- Author(s)
  Sasaki Ritsuko、Kurebayashi Nagomi、Eguchi Hidetaka、Horimoto Yoshiya、Shiga Takahiro、Miyazaki Sakiko、Kashiyama Taku、Akamatsu Wado、Saito Mitsue
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3449-3462
- DOI
  10.1111/cas.15508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07301, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-19K07105
[Journal Article] Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations2022
- Author(s)
  Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2821-2821
- DOI
  10.1038/s41467-022-30429-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02411, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR22022
- Author(s)
  Kurebayashi Nagomi、Murayama Takashi、Ota Ryosaku、Suzuki Junji、Kanemaru Kazunori、Kobayashi Takuya、Ohno Seiko、Horie Minoru、Iino Masamitsu、Yamashita Fumiyoshi、Sakurai Takashi
- Journal Title
  
  Journal of General Physiology
  
  Volume: 154 Issue: 9
- DOI
  10.1085/jgp.202112869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20H03423, KAKENHI-PROJECT-20H03430, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] NRSF- GNAO1 Pathway Contributes to the Regulation of Cardiac Ca 2+ Homeostasis2022
- Author(s)
  Inazumi Hideaki、Kuwahara Koichiro、Nakagawa Yasuaki、et al.
- Journal Title
  
  Circulation Research
  
  Volume: 130 Issue: 2 Pages: 234-248
- DOI
  10.1161/circresaha.121.318898
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07297, KAKENHI-PROJECT-19K08580, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-20H03673, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K07299, KAKENHI-PROJECT-21K08126, KAKENHI-PROJECT-20K17077, KAKENHI-PROJECT-22K08099
[Journal Article] Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes2022
- Author(s)
  Tsuboi Yoshitaka、Oyama Kotaro、Kobirumaki-Shimozawa Fuyu、Murayama Takashi、Kurebayashi Nagomi、Tachibana Toshiaki、Manome Yoshinobu、Kikuchi Emi、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、Nishino Ichizo、Mori Shuichi、Ishida Ryosuke、Kagechika Hiroyuki、Suzuki Madoka、Fukuda Norio、Yamazawa Toshiko
- Journal Title
  
  Journal of General Physiology
  
  Volume: 154 Issue: 11
- DOI
  10.1085/jgp.202213136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06789, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21K19929, KAKENHI-PLANNED-22H05053, KAKENHI-PLANNED-22H05054, KAKENHI-PLANNED-22H05055, KAKENHI-PROJECT-20H03421, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24778, KAKENHI-PROJECT-23K24067
[Journal Article] Development of a water-soluble ryanodine receptor 1 inhibitor2022
- Author(s)
  Ishida Ryosuke、Mori Shuichi、Murayama Takashi、Nakamichi Ayaka、Chai Xikun、Kurebayashi Nagomi、Iinuma Hiroto、Kagechika Hiroyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 74 Pages: 117027-117027
- DOI
  10.1016/j.bmc.2022.117027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K15244, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating2022
- Author(s)
  Oyama Kotaro、Zeeb Vadim、Yamazawa Toshiko、Kurebayashi Nagomi、Kobirumaki-Shimozawa Fuyu、Murayama Takashi、Oyamada Hideto、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、Nishino Ichizo、Harada Yoshie、Fukuda Norio、Ishiwata Shin’ichi、Suzuki Madoka
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 32
- DOI
  10.1073/pnas.2201286119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-21K06789, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21K19929, KAKENHI-PLANNED-20H05785, KAKENHI-PLANNED-22H05053, KAKENHI-PLANNED-22H05054, KAKENHI-PLANNED-22H05055, KAKENHI-PROJECT-20H03421, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K23847, KAKENHI-PROJECT-23K24778, KAKENHI-PROJECT-23K24067
[Journal Article] A reconstituted depolarization-induced Ca2+ release platform for validation of skeletal muscle disease mutations and drug discovery2022
- Author(s)
  Murayama Takashi、Kurebayashi Nagomi、Numaga-Tomita Takuro、Kobayashi Takuya、Okazaki Satoru、Yamashiro Kyosuke、Nakada Tsutomu、Mori Shuichi、Ishida Ryosuke、Kagechika Hiroyuki、Yamada Mitsuhiko、Sakurai Takashi
- Journal Title
  
  Journal of General Physiology
  
  Volume: 154 Issue: 12
- DOI
  10.1085/jgp.202213230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-22K06828, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] Therapeutic effects of novel type1 ryanodine receptor inhibitor on skeletal muscle diseases2022
- Author(s)
  Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、Murayama Takashi
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 157 Issue: 1 Pages: 15-22
- DOI
  10.1254/fpj.21068
- NAID
  130008138777
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11368
[Journal Article] The Ryanodine Receptor as a Sensor for Intracellular Environments in Muscles2021
- Author(s)
  Kobayashi Takuya、Kurebayashi Nagomi、Murayama Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 19 Pages: 10795-10795
- DOI
  10.3390/ijms221910795
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-19H03404
[Journal Article] Differential effects of the formin inhibitor SMIFH2 on contractility and Ca 2+ handling in frog and mouse cardiomyocytes2021
- Author(s)
  Sakata Koji、Matsuyama Sho、Kurebayashi Nagomi、Hayamizu Kengo、Murayama Takashi、Nakamura Kunihide、Kitamura Kazuo、Morimoto Sachio、Takeya Ryu
- Journal Title
  
  Genes to Cells
  
  Volume: 26 Issue: 8 Pages: 583-595
- DOI
  10.1111/gtc.12873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07297, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07355, KAKENHI-PROJECT-19H03404
[Journal Article] Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation2021
- Author(s)
  Itoh Hideki、Murayama Takashi、Kurebayashi Nagomi、Ohno Seiko、Kobayashi Takuya、Fujii Yusuke、Watanabe Masaya、Ogawa Haruo、Anzai Toshihisa、Horie Minoru
- Journal Title
  
  Journal of Electrocardiology
  
  Volume: 69 Pages: 111-118
- DOI
  10.1016/j.jelectrocard.2021.09.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K08473, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-21H02411
[Journal Article] A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke2021
- Author(s)
  Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、Konishi Masato、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 4293-4293
- DOI
  10.1038/s41467-021-24644-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04922, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19K06955, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K11368, KAKENHI-PROJECT-21K19752, KAKENHI-PROJECT-19H03404
[Journal Article] Purification of Recombinant Wild Type and Mutant Ryanodine Receptors Expressed in HEK293 Cells2021
- Author(s)
  Hu Yifan、Iyer Kavita、Nayak Ashok、Kurebayashi Nagomi、Murayama Takashi、Samso Montserrat
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 11 Issue: 15
- DOI
  10.21769/bioprotoc.4112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
[Journal Article] Loss-of-function mutations in cardiac ryanodine receptor channel cause various types of arrhythmias including long QT syndrome2021
- Author(s)
  Hirose Sayako、Murayama Takashi、Tetsuo Naoyuki、Hoshiai Minako、Kise Hiroaki、Yoshinaga Masao、Aoki Hisaaki、Fukuyama Megumi、Wuriyanghai Yimin、Wada Yuko、Kato Koichi、Makiyama Takeru、Kimura Takeshi、Sakurai Takashi、Horie Minoru、Kurebayashi Nagomi、Ohno Seiko
- Journal Title
  
  EP Europace
  
  Volume: 24 Issue: 3 Pages: 497-510
- DOI
  10.1093/europace/euab250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08538, KAKENHI-PROJECT-19K08555, KAKENHI-PROJECT-21H02888, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K17113, KAKENHI-PROJECT-19H03404
[Journal Article] Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother.2021
- Author(s)
  Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 141 Pages: 111800-111800
- DOI
  10.1016/j.biopha.2021.111800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08866, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-19H03404
[Journal Article] Enhanced CICR activity reduces ER Ca2+ level in cells expressing CPVT-linked mutant RyR22021
- Author(s)
  Kurebayashi Nagomi、Murayama Takashi、Ohta Ryosaku、Suzuki Junji、Kanemaru Kazunori、Ohno Seiko、Horie Minoru、Iino Masamitsu、Yamashita Fumiyoshi、Sakurai Takashi
- Journal Title
  
  Biorxiv
  
  Volume: -
- DOI
  10.1101/2021.01.16.426980
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07105
[Journal Article] Molecular basis for gating and regulation of cardiac ryanodine receptor: underlying mechanisms for gain- and loss-of function mutations2020
- Author(s)
  Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
- Journal Title
  
  Biorxiv
  
  Volume: -
- DOI
  10.1101/2020.11.30.401026
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07105
[Journal Article] A novel RyR1 inhibitor prevents and rescues sudden death in a mouse model of malignant hyperthermia and heat stroke2020
- Author(s)
  Yamazawa Toshiko、Kobayashi Takuya、Kurebayashi Nagomi、19人省略、Murayama Takashi
- Journal Title
  
  Biorxiv
  
  Volume: -
- DOI
  10.1101/2020.07.02.185520
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020
- Author(s)
  Yamazawa Toshiko、Ogawa Haruo、Murayama Takashi、Yamaguchi Maki、Oyamada Hideto、Suzuki Junji、Kurebayashi Nagomi、Kanemaru Kazunori、Oguchi Katsuji、Sakurai Takashi、Iino Masamitsu
- Journal Title
  
  The Journal of General Physiology
  
  Volume: 152 Issue: 1 Pages: 0-0
- DOI
  10.1085/jgp.201812235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19H03404
[Journal Article] Co-Phenotype of Left Ventricular Non-Compaction Cardiomyopathy and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia in Association With R169Q, a <i>Ryanodine Receptor Type 2</i> Missense Mutation2020
- Author(s)
  Nozaki Y, Kato Y, Uike K, Yamamura K, Kikuchi M, Yasuda M, Ohno S, Horie M, Murayama T, Kurebayashi N, Horigome H
- Journal Title
  
  Circ J
  
  Volume: 84 Issue: 2 Pages: 226-234
- DOI
  10.1253/circj.CJ-19-0720
- NAID
  130007789920
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2020-01-24
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07813, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K19820, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-18K07875
[Journal Article] Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies2020
- Author(s)
  Ogawa Haruo、Kurebayashi Nagomi、Yamazawa Toshiko、Murayama Takashi
- Journal Title
  
  Journal of Muscle Research and Cell Motility
  
  Volume: in press Issue: 2 Pages: 0-0
- DOI
  10.1007/s10974-020-09575-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-16H04748, KAKENHI-PROJECT-19H03404
[Journal Article] RyR2 mutation-linked arrhythmogenic diseases and its therapeutic strategies2020
- Author(s)
  Kurebayashi Nagomi、Murayama Takashi
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 155 Issue: 4 Pages: 225-229
- DOI
  10.1254/fpj.20017
- NAID
  130007867553
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
[Journal Article] Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM2020
- Author(s)
  Iyer Kavita A.、Hu Yifan、Nayak Ashok R.、Kurebayashi Nagomi、Murayama Takashi、Sams? Montserrat
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 31 Pages: 0-0
- DOI
  10.1126/sciadv.abb2964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404
[Journal Article] Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay2019
- Author(s)
  Mori Shuichi、Iinuma Hiroto、Manaka Noriaki、Ishigami-Yuasa Mari、Murayama Takashi、Nishijima Yoshiaki、Sakurai Akiko、Arai Ryota、Kurebayashi Nagomi、Sakurai Takashi、Kagechika Hiroyuki
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 179 Pages: 837-848
- DOI
  10.1016/j.ejmech.2019.06.076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03404
[Journal Article] Assays for Modulators of Ryanodine Receptor (RyR)/Ca 2+ Release Channel Activity for Drug Discovery for Skeletal Muscle and Heart Diseases2019
- Author(s)
  Murayama Takashi、Kurebayashi Nagomi
- Journal Title
  
  Current Protocols in Pharmacology
  
  Volume: 87 Issue: 1 Pages: 0-0
- DOI
  10.1002/cpph.71
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03404
[Journal Article] A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain2019
- Author(s)
  Uzu Miaki、Nonaka Miki、Miyano Kanako、Sato Hiromi、Kurebayashi Nagomi、Yanagihara Kazuyoshi、Sakurai Takashi、Hisaka Akihiro、Uezono Yasuhito
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 1 Pages: 109-112
- DOI
  10.1016/j.jphs.2019.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-18K15037
[Journal Article] A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca2+ sensitivity2018
- Author(s)
  Murayama Takashi、Ogawa Haruo、Kurebayashi Nagomi、Ohno Seiko、Horie Minoru、Sakurai Takashi
- Journal Title
  
  Communications Biology
  
  Volume: 1 Issue: 1 Pages: 98-98
- DOI
  10.1038/s42003-018-0103-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-15K08243
[Journal Article] Efficient high-throughput screening by ER Ca2+measurement to identify inhibitors of ryanodine receptor Ca2+-release channels2018
- Author(s)
  Murayama Takashi、Kurebayashi Nagomi、Ikegami-Yuasa Mari、Mori Shuichi、Suzuki Yukina、Akima Ryunosuke、Ogawa Haruo、Suzuki Junji、Kanemaru Kazunori、Oyamada Hideto、Kiuchi Yuji、Iino Masamitsu、Kagechika Hiroyuki、Sakurai Takashi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: - Issue: 1 Pages: 722-730
- DOI
  10.1124/mol.117.111468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08243, KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-25221304
[Journal Article] Therapeutic potential of ghrelin and des-acyl ghrelin against chemotherapy-induced cardiotoxicity2017
- Author(s)
  Nonaka Miki、Kurebayashi Nagomi、Murayama Takashi、Sugihara Masami、Terawaki Kiyoshi、Shiraishi Seiji、Miyano Kanako、Hosoda Hiroshi、Kishida Shosei、Kangawa Kenji、Sakurai Takashi、Uezono Yasuhito
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: Suppl. Pages: S35-S39
- DOI
  10.1507/endocrj.64.S35
- NAID
  130007307943
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507
[Journal Article] Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle2016
- Author(s)
  Hashimoto M, Doi M, Kurebayashi N, Furukawa K, Hirawake-Mogi H, Ohmiya Y, Sakurai T, Mita T, Mikoshiba K, Nara T.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 6(12) Issue: 12 Pages: 1178-1185
- DOI
  10.1002/2211-5463.12126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-16K15268
[Journal Article] A type 2 ryanodine receptor variant associated with reduced Ca2+ release and short-coupled torsade de pointe ventricular arrhythmia.2016
- Author(s)
  Fujii Y, Horie M, et al.
- Journal Title
  
  Heart Rhythm
  
  Volume: 14 Issue: 1 Pages: 98-107
- DOI
  10.1016/j.hrthm.2016.10.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-25460406, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-15K09689
[Journal Article] Genotype-phenotype correlations of malignant hyperthermia and central core disease mutations in the central region of the RYR1 channel.2016
- Author(s)
  Murayama, T., Kurebayashi, N., Ogawa, H., Yamazawa, T., Oyamada, H., Suzuki, J., Kanemaru, K., Oguchi, K., Iino, M. and Sakurai, T.
- Journal Title
  
  Hum Mutat.
  
  Volume: 37 Issue: 11 Pages: 1231-1241
- DOI
  10.1002/humu.23072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H04748
[Journal Article] Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity.2016
- Author(s)
  Uehara A, Horie M, et al.
- Journal Title
  
  Journal of General Physiology
  
  Volume: 149 Issue: 2 Pages: 199-218
- DOI
  10.1085/jgp.201611624
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04818, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-26460305, KAKENHI-PROJECT-16K08507
[Journal Article] Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.2015
- Author(s)
  Murayama T, Kurebayashi N, Yamazawa T, Oyamada H, Suzuki J, Kanemaru K, Oguchi K, Iino M, Sakurai T.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0130606-e0130606
- DOI
  10.1371/journal.pone.0130606
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243, KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25460303
[Journal Article] A dominant negative form of inositol 1,4,5-trisphosphate receptor induces metacyclogenesis and increases mitochondrial density in Trypanosoma cruzi.2015
- Author(s)
  Hashimoto M, Nara T, Enomoto M, Kurebayashi N, Yoshida M, Sakurai T, Mita T, Mikoshiba K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 466 Issue: 3 Pages: 475-480
- DOI
  10.1016/j.bbrc.2015.09.053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-25670205, KAKENHI-PROJECT-24390102
[Journal Article] キーワード解説：カルシウム・膜電位イメージング2014
- Author(s)
  呉林なごみ
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 143 Pages: 45-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590331
[Journal Article] Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model2014
- Author(s)
  Sugihara M, Odagiri F, Suzuki T, Murayama T, Nakazato Y, Unuma K, Yoshida K, Daida H, Sakurai T, Morimoto S, Kurebayashi N.
- Journal Title
  
  PLoS One
  
  Volume: 8(1) Issue: 1 Pages: e55514-e55514
- DOI
  10.1371/journal.pone.0055514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249038, KAKENHI-PROJECT-23300145, KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24590331, KAKENHI-PROJECT-24790639, KAKENHI-PUBLICLY-25136718, KAKENHI-PUBLICLY-23136514
[Journal Article] Assembly of the cochlear gap junction macromolecular complex requires connexin 26.2014
- Author(s)
  Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K.
- Journal Title
  
  J Clin Invest,
  
  Volume: 124 Issue: 4 Pages: 1598-1607
- DOI
  10.1172/jci67621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22110007, KAKENHI-PROJECT-24501325, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718, KAKENHI-PROJECT-25293351, KAKENHI-PROJECT-25462653, KAKENHI-PROJECT-25670721, KAKENHI-PROJECT-221S0001
[Journal Article] キーワード解説：カルシウム・膜電位イメージング.2014
- Author(s)
  呉林なごみ
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 143 Pages: 45-46
- Open Access
- Data Source
  KAKENHI-PROJECT-24590331
[Journal Article] Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice.2014
- Author(s)
  Odagiri, F., H. Inoue, M. Sugihara, T. Suzuki, T. Murayama, T. Shioya, M. Konishi, Y. Nakazato, H. Daida, T. Sakurai, S. Morimoto, N. Kurebayashi
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 7 Pages: e101838-e101838
- DOI
  10.1371/journal.pone.0101838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-25136718
[Journal Article] キーワード解説：カルシウム・膜電位イメージング2014
- Author(s)
  呉林なごみ
- Journal Title
  
  日本薬理学雑誌.
  
  Volume: 143 Pages: 45-46
- Open Access
- Data Source
  KAKENHI-PUBLICLY-25136718
[Journal Article] キーワード解説：カルシウム・膜電位イメージング2014
- Author(s)
  呉林なごみ
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 143 Pages: 45-46
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25136718
[Journal Article] Inositol 1,4,5-Trisphosphate receptor regulates replication, differentiation, infectivity, and virulence of the parasitic protist Trypanosoma cruzi2013
- Author(s)
  Hashimoto M
- Journal Title
  
  Mol Microbiology
  
  Volume: 87(6) Issue: 6 Pages: 1133-50
- DOI
  10.1111/mmi.12155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PROJECT-22310158, KAKENHI-PROJECT-23402046, KAKENHI-PROJECT-24390102, KAKENHI-PROJECT-24590331, KAKENHI-PROJECT-25221002, KAKENHI-PUBLICLY-23136514
[Journal Article] 筋小胞体のCa2+放出機構の最近の進歩2012
- Author(s)
  呉林なごみ
- Journal Title
  
  生体の科学
  
  Volume: 63 Pages: 374-375
- Data Source
  KAKENHI-PUBLICLY-23136514
[Journal Article] 筋小胞体のCa2+放出機構の最近の進歩2012
- Author(s)
  呉林なごみ, 村山尚
- Journal Title
  
  生体の科学
  
  Volume: 63 Pages: 374-375
- Data Source
  KAKENHI-PROJECT-24590331
[Journal Article] Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy2012
- Author(s)
  Suzuki T, Shioya T, Murayama T, Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H, Morimoto S, Kurebayashi N
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 4 Pages: e35353-e35353
- DOI
  10.1371/journal.pone.0035353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24590331, KAKENHI-PUBLICLY-23136514
[Journal Article] Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy2012
- Author(s)
  Suzuki T, Shioya T, Murayama T,Sugihara M, Odagiri F, Nakazato Y, Nishizawa H, Chugun A, Sakurai T, Daida H, Morimoto S, Kurebayashi N
- Journal Title
  
  PLoS ONE
  
  Volume: 7(4)
- Data Source
  KAKENHI-PROJECT-23300145
[Journal Article] Two ryanodine receptor isoforms in nonmammalian vertebrate skeletal muscle : Possible roles in excitation-contraction coupling and other processes2011
- Author(s)
  Murayama T, Kurebayashi N
- Journal Title
  
  Prog Biophys Mol Biol
  
  Volume: 105 Pages: 134-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500383
[Journal Article] Role of amino-terminal half of the S4-S5 linker in type 1 ryanodine receptor(RyR1) channel gating2011
- Author(s)
  Murayama T, Kurebayashi N, Oba T, Oyamada H, Oguchi K, Sakurai T, Ogawa Y
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 35571-35577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500383
[Journal Article] リアノジン受容体2010
- Author(s)
  呉林なごみ, 村山尚
- Journal Title
  
  生体の科学
  
  Volume: 61 Pages: 444-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500383
[Journal Article] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008
- Author(s)
  Kurebayashi, N.
- Journal Title
  
  J Physiol Sci 58
- NAID
  130007039350
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Aberrant Cell-to-Cell Coupling in Ca^<2+>-Overloaded Guinea Pig Ventricular Muscles2008
- Author(s)
  Kurebayashi, Nagomi
- Journal Title
  
  Am JPhysiol Cell Physiol
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Aberrant Cell-to-Cell Coupling in Ca^<2+>-Overloaded Guinea Pig Ventricular Muscles2008
- Author(s)
  Kurebayashi, Nagomi
- Journal Title
  
  Am J Physiol:Cell Physiol 294
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Mechanism of Arrhythmogenesis in DCM Medel Mice Associated with Cardiac Troponin T mutation2008
- Author(s)
  Kurebayashi, N.
- Journal Title
  
  Biophys J
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Aberrant Cell-to-Cell Coupling in Ca^2+-Overloaded Guinea Pig Ventricular Muscles2008
- Author(s)
  Kurebayashi, N.
- Journal Title
  
  Am J Physiol-Cell Physiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Chracteristics of automatic activity in knock-in mouse model of dilated cardiomyopathy associated with δK210 mutation in cardiac troponin T2007
- Author(s)
  Nagomi Kurebayashi, A.Chugun, H.Nishizawa, Y.Nakazato, H.Daida, T.Sakurai, S.Morimoto
- Journal Title
  
  J. Pharmacological Science 103
  
  Pages: 74-74
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Cell-to-Cell propagation of excitation in cardiac muscles determined by Ca2+ and membrane potential imaging2007
- Author(s)
  N.Kurebayashi, H.Nishizawa, Y.Nakazato
- Journal Title
  
  Biophysical J. Abstracts
  
  Pages: 344-344
- Data Source
  KAKENHI-PROJECT-18590241
[Journal Article] Increased automaticity in ventricular muscle from dilated cardiomyopathy associated with δK210 mutation in cardiac troponin T2007
- Author(s)
  A.Chugun, H.Nishizawa, Y.Nakazato, H.Daida, T Sakurai, S.Morimoto, N.Kurebayashi
- Journal Title
  
  Biophysical J. Abstracts
  
  Pages: 622-622
- Data Source
  KAKENHI-PROJECT-18590241
[Patent] ２型リアノジン受容体活性抑制剤2022
- Inventor(s)
  國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  順天堂大学、東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-19K07105
[Patent] ２型リアノジン受容体活性抑制剤2021
- Inventor(s)
  國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  学校法人順天堂、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03404
[Patent] ２型リアノジン受容体活性抑制剤2021
- Inventor(s)
  国広なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  国広なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K07105
[Patent] ２型リアノジン受容体活性抑制剤2021
- Inventor(s)
  國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  学校法人順天堂、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03404
[Patent] ２型リアノジン受容体活性抑制剤2020
- Inventor(s)
  國廣なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  学校法人順天堂、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-020656
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03404
[Patent] ２型リアノジン受容体活性抑制剤2020
- Inventor(s)
  国広なごみ、村山尚、影近弘之、森修一、湯浅磨里、飯沼大翔
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-020656
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K07105
[Patent] リアノジン受容体阻害薬2018
- Inventor(s)
  影近弘之、國廣なごみ、村山尚、森修一、湯浅磨里
- Industrial Property Rights Holder
  学校法人順天堂、国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15K08243
[Patent] リアノジン受容体阻害薬2017
- Inventor(s)
  村山尚、国広なごみ、影近弘之、森修一、湯浅磨里
- Industrial Property Rights Holder
  村山尚、国広なごみ、影近弘之、森修一、湯浅磨里
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-205935
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K08243
[Patent] Ca2+誘発性Ca2+遊離活性抑制剤のスクリーニング方法2016
- Inventor(s)
  村山尚, 國廣なごみ
- Industrial Property Rights Holder
  村山尚, 國廣なごみ
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-113147
- Filing Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Kurebayashi Nagomi2024
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  第101回　日本生理学会大会, 小倉
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] Effects of a high-affinity and selective RyR2 inhibitor on Ca2+ signals in cardiomyocytes and arrhythmias in CPVT model mice2024
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Biophysical Society Annual Meeting, Philadelphia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の頻度と詳細2023
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] Effects of a novel RyR2 selective inhibitor on malignant arrhythmias in CPVT model mice2023
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  FAOPS Congress 2023, at daegu　韓国
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] EFFECTS OF VOLUNTARY EXERCISE AND ADMINISTRATION OF RENIN ANGIOTENSIN INHIBITOR ON CARDIAC FUNCTION IN INHERITED DILATED CARDIOMYOPATHY MODEL2023
- Author(s)
  Masami Sugihara,Ryo Kakigi,Takashi Murayam,Takashi Miida,Takashi Sakura,,Sachio Morimoto,Nagomi Kurebayashi
- Organizer
  第67回米国生物物理学会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, U-Inoue Y, Inoue T, Satoru N and Sakurai T
- Organizer
  第100回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] The effects of microtubule depolymerization on muscular viscoelastic properties.2023
- Author(s)
  T Kobayashi, N Kurebayashi, Murayama, T Sakurai, M Kaya
- Organizer
  The 5th Rocky Mountain Muscle Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11368
[Presentation] 骨格筋の粘弾性における微小管の役割2023
- Author(s)
  小林琢也, 茅元司,呉林なごみ, 村山尚, 櫻井隆
- Organizer
  第６１回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K11368
[Presentation] The effects of microtubule depolymerization on muscular viscoelastic properties.2023
- Author(s)
  T Kobayashi, N Kurebayashi, Murayama, T Sakurai, M Kaya
- Organizer
  The 5th Rocky Mountain Muscle Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K10692
[Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, Inoue YU, Inoue T, Noguchi S and Sakurai T
- Organizer
  67th Biophysical Society Anual lMeeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] Relationship between disease phenotype and mutant RyR2 channel activity in CPVT mouse models,2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, U-Inoue Y, Inoue T, Satoru N and Sakurai T
- Organizer
  第100回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Arrhythmia severity in mouse models harboring RyR2 mutations with varied extent of channel activity2023
- Author(s)
  Kurebayashi N, Kodama M, Murayama T, Sugihara M, Konishi M, Miura A, Nishio H, Inoue YU, Inoue T, Noguchi S and Sakurai T
- Organizer
  67th Biophysical Society Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Development of RyR2 inhibitors and verification of their effects on CPVT mouse models2023
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  オーストラリア生理学会, 日豪合同シンポジウム, メルボルン
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 骨格筋の粘弾性における微小管の役割2023
- Author(s)
  小林琢也, 茅元司,呉林なごみ, 村山尚, 櫻井隆
- Organizer
  第６１回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K10692
[Presentation] A novel, high-affinity and selective RyR2 inhibitor effectively suppresses lethal arrhythmias in CPVT mouse models2023
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Gordon Reserach Conference, Muscle: Excitation-contraction coupling
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 微小管脱重合薬により骨格筋の粘弾性は変化する2022
- Author(s)
  小林琢也, 村山尚, 呉林なごみ
- Organizer
  第６０回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K11368
[Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、石田良典、森修一、影近弘之、山田充彦、櫻井隆．
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24067
[Presentation] RyR2発現細胞におけるCa2+オシレーションと小胞体Ca2+レベルの調節メカニズム2022
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆
- Organizer
  第99回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 骨格筋脱分極誘発性Ca2+遊離（DICR）再構成系の開発2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、山田充彦、櫻井隆
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 骨格筋疾患治療薬開発のための脱分極誘発性Ca2+遊離再構成プラットフォームの構築2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、石田良典、森修一、影近弘之、山田充彦、櫻井隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] DIFFERENTIAL IMPACTS OF ARRHYTHMIA-LINKED LOSS-OF-FUNCTION RYR2 MUTATIONS ON CA2+ SIGNALING IN CARDIAC CELLS.2022
- Author(s)
  Nagomi Kurebayashi, Takashi Murayama, Naoyuki Tetsuo, Sayako Hirose, Minoru Horie, Seiko Ohno, Takashi Sakurai
- Organizer
  66th Annual Meeting of the Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍（CPVT）に対する抗不整脈薬の評価2022
- Author(s)
  呉林なごみ, 児玉昌美, 村山尚, 杉原匡美, 石井光一郎, 岡部雄太, 村越伸行, 三浦綾, 西尾元, 井上-上野由紀子, 井上高良, 野口悟, 中村衣里, 金井富三夫, 多田昇弘, 櫻井隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 拡張型心筋症モデルマウスにおける自発運動とレニン・アンギオテンシン阻害剤投与の比較2022
- Author(s)
  杉原匡美、柿木亮、村山尚、櫻井隆、三井田孝、森本幸生、呉林なごみ
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] 複数のRyR2変異マウスモデル系統を用いたカテコラミン誘発性多型性心室頻拍（CPVT）に対する抗不整脈薬の評価2022
- Author(s)
  呉林なごみ, 児玉昌美, 村山尚, 杉原匡美, 石井光一郎, 岡部雄太, 村越伸行, 三浦綾, 西尾元, 井上-上野由紀子, 井上高良, 野口悟, 中村衣里, 金井富三夫, 多田昇弘櫻井隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06652
[Presentation] 骨格筋脱分極誘発性Ca2+遊離（DICR）再構成系の開発2022
- Author(s)
  村山尚、呉林なごみ、冨田（沼賀）拓郎、小林琢也、中田勉、山田充彦、櫻井隆
- Organizer
  第8回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24067
[Presentation] 機能喪失型催不整脈性RyR2変異が引き起こす様々なCa2+動態異常2022
- Author(s)
  呉林なごみ，村山尚，哲翁直之，廣瀬紗也子，堀江稔，大野聖子，櫻井隆
- Organizer
  第95回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] CPVTモデルマウスに対するRyR2特異的阻害薬の効果2021
- Author(s)
  呉林なごみ, 村山尚, 石井光一郎, 小西真人, 杉原匡美, 森修一, 飯沼大翔, 湯浅磨里, 村越伸行, 影近弘之, 櫻井隆
- Organizer
  第94回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 拡張型心筋症モデルマウスにおける自発運動の効果2021
- Author(s)
  杉原匡美、柿木亮、村山尚、三井田孝、櫻井隆、森本幸生、呉林なごみ
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11246
[Presentation] 新規1型リアノジン受容体（RyR1）阻害剤の結合部位の同定．2021
- Author(s)
  村山尚、呉林なごみ、小林琢也、小川治夫、児玉昌美、森修一、影近弘之、櫻井隆．
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] クライオ電子顕微鏡による心筋型リアノジン受容体loss-of-function変異体の解析2021
- Author(s)
  小川治夫、小林琢也、包明久、呉林なごみ、斎藤慧、児玉昌美、櫻井隆、吉川雅英、村山尚
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] Search for RyR2 inhibitors and verification of their effects on arrhythmogenic myocardium2021
- Author(s)
  呉林なごみ
- Organizer
  第126回日本解剖学会・第98回日本生理学会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 骨格筋脱分極誘発性Ca2+遊離（DICR）再構成系を用いた筋疾患へのアプローチ2021
- Author(s)
  村山尚、呉林なごみ、小林琢也、岡﨑諭、山代暁介、櫻井隆
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 新規1型リアノジン受容体（RyR1）阻害薬の結合部位の探索．2020
- Author(s)
  村山尚、呉林なごみ、小林琢也、小川治夫、児玉昌美、森修一、影近弘之、櫻井隆．
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] Characterization of novel RyR1-selective inhibitors identified by high-throughput screening using ER Ca2+ measurement.2020
- Author(s)
  Matsukawa H, Murayama T, Kobayashi T, Kurebayashi N, Yamazawa T, Ishigami-Yuasa M, Mori S, Kagechika H, Sakurai T.
- Organizer
  Biophysical Society 64th Annual Meeting
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 不整脈疾患におけるRyR2の異常とCICR2020
- Author(s)
  呉林なごみ
- Organizer
  第93回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Therapeutic effects of a novel RyR1 inhibitor on malignant hyperthermia model mice.2020
- Author(s)
  Murayama T, Yamazawa T, Kobayashi T, Kurebayashi N, Noguchi S, Nishino N, Mori S, Kagechika H, Lopez JR, Allen PD, Sakurai T.
- Organizer
  Biophysical Society 64th Annual Meeting
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 新規RyR1抑制薬の悪性高熱症モデルマウスに対する効果．2020
- Author(s)
  村山尚，山澤徳志子，小林琢也，呉林なごみ，野口悟，西野一三，森修一，影近弘之，Jose R. Lopez，Paul D. Allen，櫻井隆．
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] 小胞体内Ca2+濃度測定により新たに同定されたRyR1選択的阻害剤の性質の検討．2020
- Author(s)
  松川紘之、村山尚、小林琢也、呉林なごみ、山澤徳志子、湯浅磨里、森修一、影近弘之、櫻井隆．
- Organizer
  第6回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] Effects of novel RyR2 inhibitors on cardiac myocytes from diseased hearts2020
- Author(s)
  Nagomi Kurebayashi, Takashi Murayama, Masato Konishi, Shuichi Mori, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Haruo Ogawa, Sachio Morimoto, Takashi Sakurai
- Organizer
  63th Annual Meeting of the Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] 不整脈疾患におけるRyR2の異常とCICR.2020
- Author(s)
  呉林なごみ
- Organizer
  第93回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Mechanism and therapeutic strategies for arrhythmogenic diseases caused by RyR2 mutations2019
- Author(s)
  呉林なごみ
- Organizer
  FAOPS2019（第9回アジア・オセアニア生理学会連合2019年大会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Ryanodine receptor type 2 as a potential target for novel anti-arrhythmic drugs2019
- Author(s)
  Kurebayashi, N
- Organizer
  The 71th Annual Meeting of the Korean Physiological Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Mechanism and therapeutic strategies for arrhythmogenic diseases caused by RyR2 mutations2019
- Author(s)
  Nagomi Kurebayashi
- Organizer
  9th FAOPS Congress, Symposium25 Calcium signaling in heart disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105
[Presentation] Arrhythmias caused by abnormal Ca2+ homeostasis and the treatment strategies2019
- Author(s)
  呉林なごみ
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 悪性高熱症モデルマウスを用いた新規RyR1阻害薬の治療効果の検討．2019
- Author(s)
  村山尚、山澤徳志子、小林琢也、呉林なごみ、野口悟、井上高良、井上由紀子、森修一、飯沼大翔、間中紀暁、湯浅磨里、影近弘之、西野一三、櫻井隆．
- Organizer
  第5回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] High Throughput Screening of Type 2 Ryanodine Receptor Inhibitors by Monitoring Endoplasmic Reticulum Ca2+2018
- Author(s)
  Tamura M, Kurebayashi N, Murayama T, Mori S, Ishigami-Yuasa M, Kagechika H, Suzuki J, Kanemaru K, Iino M & Sakurai T.
- Organizer
  62nd Biophysical Society Annual Meeting (USA)
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 2型リアノジン受容体と心疾患2018
- Author(s)
  呉林なごみ
- Organizer
  日本筋学会第4回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Ryanodine receptor Ca2+ release channels and cardiac arrhythmia.2018
- Author(s)
  Kurebayashi, N
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Regulation of Store Ca2+ Level in HEK293 Cells Expressing Type 2 Ryanodine Receptor (RyR2) with CPVT Mutations.2018
- Author(s)
  Kurebayashi N, Murayama T, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M & Sakurai T.
- Organizer
  62nd Biophysical Society Annual Meeting (USA)
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Divergent effects of disease-linked mutations in RyR2 on Ca2+ dynamics in cardiac and non-cardiac cells2018
- Author(s)
  呉林なごみ
- Organizer
  第95回　日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Regulation of Store Ca2+ Level in HEK293 Cells Expressing Type 2 Ryanodine Receptor (RyR2) with CPVT Mutations.2018
- Author(s)
  Kurebayashi N, Murayama T, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M, and Sakurai T.
- Organizer
  62th Biophysical Society Annual Meeting, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Effects of CICR activity and expression levels of RyR2 on Ca2+ homeostasis in HEK293 cells.2017
- Author(s)
  Kurebayashi N, Murayama T, Tetsuo N, Ohta R, Yamashita F, Suzuki J, Kanemaru K, Iino M & Sakurai T.
- Organizer
  Calcium Binding Protein Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 小胞体Ca2+モニタリングによるRyR2抑制薬および活性化薬の探索.2017
- Author(s)
  呉林なごみ, 村山尚, 田村真衣, 哲翁直之, 湯浅磨里, 森修一, 影近弘之, 鈴木純二, 金丸和典, 飯野正光 & 櫻井隆
- Organizer
  第27回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] MODULATION OF CA2+ SIGNALING IN HL-1 CARDIOMYOCYTES BY ARRHYTHMOGENIC RYR2 MUTANTS.2017
- Author(s)
  Naoyuki Tetsuo, Nagomi Kurebayashi, Takashi Murayama, Takashi Sakurai
- Organizer
  61th Biophysical Society Annual Meeting
- Place of Presentation
  New Orleans, LO, USA
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 疾患変異を有するRyR2が引き起こす細胞内Ca2+動態の変調.2017
- Author(s)
  呉林なごみ, 尚村, 哲翁直之, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 黒川洵子, a櫻井隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] EFFECTS OF EXPRESSION LEVELS OF WT AND MUTANT RYR2 ON CA2+ HOMEOSTASIS IN HEK CELLS.2017
- Author(s)
  Kurebayashi N, Murayama T, Suzuki J, Kanemaru K, Iino M, Sakurai T.
- Organizer
  61th Biophysical Society Annual Meeting
- Place of Presentation
  New Orleans, LO, USA
- Year and Date
  2017-02-11
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 心筋由来培養心筋細胞のCa2+シグナリングにおける特発性心室細動（IVF)およびQT延長症候群（LQTS)変異RyR2の効果.2017
- Author(s)
  哲翁直之, 呉林なごみ, 村山尚, 黒川洵子, 櫻井隆.
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 不整脈原性RyR2変異のCa2+遊離特性―カテコラミン誘発性多型性心室頻拍（CPVT）変異と特発性心室細動（I-VF）変異の比較―2016
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下冨義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] Characterization of ca2+-induced ca2+ release via ryr2 carrying arrhythmogenic mutations2016
- Author(s)
  Kurebayashi N, Murayama T, Suzuki J, Kanemaru K, Iino M, Sakurai T.
- Organizer
  60th Biophysical Society Annual Meeting
- Place of Presentation
  Los Angels, USA
- Year and Date
  2016-02-29
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] 心室性不整脈誘発性RyR2変異体の疾患別Ca2+遊離特性.2016
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下冨義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] ２型リアノジン受容体の不整脈原性変異はCICR活性とCa2+ 動態にどのような影響を及ぼすか？2015
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆.
- Organizer
  第88回　日本薬理学会年会.
- Place of Presentation
  名古屋
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] 拡張型心筋症におけるアンジオテンシン受容体阻害薬(ARB)感受性および非感受性リモデリング.2015
- Author(s)
  呉林なごみ.
- Organizer
  第92回　日本生理学会大会.
- Place of Presentation
  神戸
- Year and Date
  2015-03-24
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] ２型リアノジン受容体の不整脈原性変異はCICR活性とCa2+ 動態にどのような影響を及ぼすか？2015
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆
- Organizer
  第88回　日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015
- Author(s)
  Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai.
- Organizer
  Biophysical society, 59th Annual Meeting.
- Place of Presentation
  ボルチモア　アメリカ合衆国
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] Contribution of Calcium-Induced Calcium Release to Calcium Homeostasis in Cells Expressing RyR2 with Disease-Associated Mutations,.2015
- Author(s)
  Kurebayashi N.
- Organizer
  Gordon Research Conference, Muscle: Excitation-contraction coupling
- Place of Presentation
  Sunday River, ME, USA
- Year and Date
  2015-05-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08243
[Presentation] ２型リアノジン受容体の不整脈原性変異はCICR活性とCa2+動態にどのような影響を及ぼすか？2015
- Author(s)
  呉林なごみ, 村山　尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井　隆
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] Effects of MH and CCD mutations in the central region on RyR1 channels.2015
- Author(s)
  Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, and Takashi Sakurai
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  ボルチモア、アメリカ合衆国
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 1型リアノジン受容体チャネルに対する中央領域疾患変異の効果2015
- Author(s)
  村山　尚、呉林なごみ、山澤徳志子、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井　隆
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015
- Author(s)
  Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai
- Organizer
  Biophysical society, 59th Annual Meeting
- Place of Presentation
  Baltimore
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] Effects of arrhythmogenic mutations on Ca2+-induced Ca2+ release activities of type 2 ryanodine receptors.2015
- Author(s)
  Kurebayashi, N., T. Murayama, J. Suzuki, K. Kanemaru, M. Iino, T. Sakurai
- Organizer
  Biophysical society, 59th Annual Meeting
- Place of Presentation
  ボルチモア、アメリカ合衆国
- Year and Date
  2015-02-11
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 1型リアノジン受容体チャネル活性に対する中央領域疾患変異の効果2015
- Author(s)
  村山　尚、呉林なごみ、山澤徳志子、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井　隆
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] Effects of MH and CCD mutations in the central region on RyR1 channels.2015
- Author(s)
  Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, and Takashi Sakurai
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  Baltimore
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] Divergent effects of disease associated mutations on type 2 ryanodine receptor channel.2014
- Author(s)
  Kurebayashi, N Murayama, T Uehara, A Yasukochi, M Sakura,i T
- Organizer
  58th Biophysical Society Annual Meeting
- Place of Presentation
  サンフランシスコ、米国
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 拡張型心筋症における構造的リモデリングと電気的リモデリングの関係.2014
- Author(s)
  呉林なごみ, 小田切史徳, 井上華, 杉原匡美, 村山尚, 木森義隆, 小西真人, 森本幸生, 櫻井隆.
- Organizer
  第130回　日本薬理学会関東部会.
- Place of Presentation
  星薬科大学（東京）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited dilated cardiomyopathy (DCM) model mice2014
- Author(s)
  Nagomi Kurebayashi Fuminori Odagiria Hana Inouec Masami Sugiharaa Takeshi Suzukia Takashi Murayama Masato Konishi Yuji Nakazato Hiroyuki Daida Takashi Sakurai Sachio Morimoto
- Organizer
  17th World Congress of Pharmacology
- Place of Presentation
  ケープタウン、南アフリカ共和国
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited dilated cardiomyopathy (DCM) model mice.2014
- Author(s)
  Kurebayashi, N., F. Odagiri, H. Inoue, M. Sugihara, T. Suzuki, T. Murayama, M. Konishi, Y. Nakazato, H. Daida, T. Sakurai, S. Morimoto.
- Organizer
  17th World Congress of Pharmacology.
- Place of Presentation
  南アフリカ　ケープタウン
- Year and Date
  2014-07-15
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] 不整脈原性2型リアノジン受容体のCICR特性2014
- Author(s)
  呉林なごみ村山尚鈴木純二金丸和典飯野正光櫻井隆
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] Effects of candesartan on progression of electrical remodeling in the hearts of inherited DCM model mice2014
- Author(s)
  Nagomi Kurebayashi, Fiminori Odagiri, Hana Inoue, Masami Sugihara, Takeshi Suzuki, Takashi Murayama, Takao Shioya, Masato Konishi, Yuji Nakazato, Hiroyuki Daida, Takashi Sakurai, Sachio Morimoto,
- Organizer
  17th World Congress of Pharmacology
- Place of Presentation
  ケープタウン、南アフリカ共和国
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 心筋型リアノジン受容体（RyR2）不整脈原性変異のCa2+ 動態とCICR活性に対する効果2014
- Author(s)
  呉林なごみ, 村山尚, 太田亮作, 山下富義, 鈴木純二, 金丸和典, 飯野正光, 櫻井隆
- Organizer
  第24回　日本循環薬理学会
- Place of Presentation
  山形テルサ、山形市
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 心室性不整脈を誘発する2型リアノジン受容体変異体のCa2+遊離の特性2014
- Author(s)
  呉林なごみ村山尚鈴木純二金丸和典飯野正光櫻井隆
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 不整脈原性2型リアノジン受容体のCICR特性2014
- Author(s)
  呉林なごみ村山尚鈴木純二金丸和典飯野正光櫻井隆
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] 心室性不整脈を誘発する2型リアノジン受容体変異体のCa2+遊離の特性2014
- Author(s)
  呉林なごみ村山尚鈴木純二金丸和典飯野正光櫻井隆
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] Divergent effects of disease associated mutations on type 2 ryanodine receptor channel.2014
- Author(s)
  Kurebayashi, N Murayama, T Uehara, A Yasukochi, M Sakura,i T
- Organizer
  58th Biophysical Society Annual Meeting
- Place of Presentation
  サンフランシスコ、米国
- Data Source
  KAKENHI-PUBLICLY-25136718
[Presentation] 拡張型心筋症モデルマウス心臓の電気的リモデリングに対するカンデサルタンの効果2013
- Author(s)
  呉林なごみ, 小田切史徳, 杉原匡美, 鈴木剛, 井上華, 村山尚, 塩谷孝雄, 小西真人, 中里祐二, 代田浩之, 櫻井隆, 森本幸生
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 遺伝性拡張型心筋症における無症候期、突然死危険期、破綻期と、これらを左右する因子2013
- Author(s)
  呉林なごみ
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京　船堀
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PUBLICLY-23136514
[Presentation] FFECTS OF ANGIOTENSIN II RECEPTOR BLOCKER ON THE PROGRESSION OF ELECTRICAL REMODELING IN HEARTS OF INHERITED DCM MODEL MICE.2013
- Author(s)
  Odagiri F, Inoue H, Sugihara M, Suzuki T, Murayama T, Shioya T, Konishi M, Nakazato Y, Daida H, Sakurai T, Morimoto S, Kurebayashi N
- Organizer
  57th Biophysical Society Annual Meeting Philadelphia
- Place of Presentation
  フィラデルフィア
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 遺伝性拡張型心筋症における無症候期、突然死危険期、破綻期と、これらを左右する因子2013
- Author(s)
  呉林なごみ
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京　船堀
- Data Source
  KAKENHI-PROJECT-24590331
[Presentation] 拡張型心筋症モデルマウス心臓の電気的リモデリングに対するカンデサルタンの効果2013
- Author(s)
  呉林なごみ
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PUBLICLY-23136514
[Presentation] Regulatory mechanisms of synchronization of action potentials and Ca2+ transients in cardiomyocytes in heart tissues2012
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-23136514
[Presentation] Multistep electrical remodeling and sudden death precede heart failure in inherited dilated cardiomyopathy2012
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  56th Biophysical Society Annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PUBLICLY-23136514
[Presentation] Role of amino-terminal half of the S4-S5 linker in the RyR1 channel gating2012
- Author(s)
  Murayama T, Kurebayashi N, Oba T, Oyamada H, Oguchi K, Sakurai T, Ogawa Y
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2012-02-27
- Data Source
  KAKENHI-PROJECT-21500383
[Presentation] 1型リアノジン受容体S4-S5リンカーはチャネルゲーティングを調節する2012
- Author(s)
  村山尚、呉林なごみ、大羽利治、小山田英人、小口勝司、小川靖男、櫻井隆
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21500383
[Presentation] 新規多機能GFPを用いたリアノジン受容体の構造機能解析2009
- Author(s)
  村山尚, 小林琢也, 樫山拓, 呉林なごみ, 木森義隆, 諸根信弘, 北井敏幸, 高萩隆行, 櫻井隆
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-21500383
[Presentation] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  J Physiol Sci 58 Suppl. : S178, Japanese Physiological Society
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Discrimination of abnormal E-C coupling from abnormal excitability in multicellular cardiac preparation by optical imaging2008
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Mechanism of Arrhythmogenesis in DCM Model Mice Associated with Cardiac Troponin T mutation2008
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Biophysical Society 52nd Annual Meeting
- Place of Presentation
  Long Beach,CA,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Mechanism of Arrhythmogenesis in DCM Medel Mice Associated with Cardiac Troponin T mutation2008
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Biophys J 303a, Biophysical Society 52nd Annual Meeting
- Place of Presentation
  Long Beach, CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Generation of the GFP-tagged type 1 ryanodine receptor mutants by transposon-based random insertion approach2008
- Author(s)
  Murayama, T, Kashiyama, T, Oyamada, H, Kobayashi, T, Kurebayashi, N, Sakurai, T
- Organizer
  Biophysical Society 52nd Annual Meeting
- Place of Presentation
  Long Beach, CA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590227
[Presentation] Cell-to-cell propagation of excitation in cardiac muscles determined by Ca^<2+> and membrane potential imaging2007
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Biophysical Society 51st Annual Meeting
- Place of Presentation
  Baltimore,MD,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Role of a cytoplasmic loop between M7b and M8 transmembrane helices of RyR1 in Ca^<2+> channel gating2007
- Author(s)
  Murayama, T, Oyamada, H, Oba, T, Oguchi, K, Kurebayashi, N
- Organizer
  Biophysical Society 51st Annual Meeting
- Place of Presentation
  Baltimore, MD
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590227
[Presentation] Characteristics of automatic activity in knock-in mouse model of dilated cardiomyopathy associated with deltaK210 in cardiac troponin T2007
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  J Pharmacol Science 103 Supplement I : 74P, Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Regulation of intracellular Ca^<2+> by intercellular communication in cardiac muscle2006
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  Muscle:Excitation/Contraction Coupling(Gordon Research Conference)
- Place of Presentation
  New London,NH,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Regulation of intracellular Ca^<2+> by intercellular communication in cardiac muscle2006
- Author(s)
  Kurebayashi, Nagomi
- Organizer
  in Muscle : Excitation / Contraction Coupling(Gordon Research Conference)
- Place of Presentation
  NH, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Ca^<2+>イメージングと膜電位イメージングによる心筋の興奮伝導遅延の検討2006
- Author(s)
  呉林なごみ
- Organizer
  循環薬理学会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590241
[Presentation] Postulated role of interdomain interactions within the type 1 ryanodine receptor in dysfunction of Ca^<2+> release channel in malignant hyperthermia2006
- Author(s)
  Murayama, T, Oyamada, H, Kurebayashi, N, Oba, T, Hara, H, Wakebe, K, Ikemoto, N, Ogawa, Y
- Organizer
  Biophysical Society 50th Annual Meeting
- Place of Presentation
  Salt Laky City, UT
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590227
[Presentation] C末端悪性高熱変異を有する1型リアノジン受容体チャネルの機能解析
- Author(s)
  村山　尚、青木良輔、赤塚祐介、呉林なごみ、小山田英人、小口勝司、櫻井　隆
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  船堀
- Data Source
  KAKENHI-PROJECT-24590330
[Presentation] 1型リアノジン受容体チャネルに対する疾患変異の多様な効果
- Author(s)
  村山　尚、呉林なごみ、小山田英人、鈴木純二、金丸和典、小口勝司、飯野正光、櫻井　隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590330
[]

1. MURAYAMA Takashi (10230012)

# of Collaborated Projects: 13 results

# of Collaborated Products: 79 results
2. Kobayashi Takuya (60468585)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
3. 小川治夫 (40292726)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
4. 杉原匡美 (80648163)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
5. OGAWA Yasuo (50103841)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MORIMOTO Sachio (50202362)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. OBA Toshiharu (50008330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. NAKAZATO Yuji (30266035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. 村越伸行 (80447218)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 茅元司 (00422098)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. 冨田拓郎 (60705060)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
12. 柿木亮 (70614931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. MORONE Nobuhiro (50399680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. TAKAHAGI Takayuki (40271069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. UEHARA Akira (60140745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOSHIDA Ken-ichi (40166947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. MORIMOTO Keiko (30220081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. UEYAMA Takashi (50264875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KUWAHIRA Ichiro (60186567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SHIRAI Mikiyasu (70162758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KATAFUCHI Toshihiko (80177401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKE Sachiko (80253425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAKAMOTO Kensaku (50240685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Aonuma Kazutaka (10375488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 原藤光 (40133334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 中郡昭人 (50236824)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 入鹿山容子 (90312834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 柳沢正史 (20202369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 森修一 (00467630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. 渡邊大輝 (30823281)

# of Collaborated Projects: 1 results

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31. 井上華 (20390700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
32. 児玉昌美 (30512248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 石田良典 (10937684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
34. 野島愛来 (90897472)

# of Collaborated Projects: 1 results

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35. 池田勝久 (70159614)

# of Collaborated Projects: 1 results

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36. 美野輪治 (00181967)

# of Collaborated Projects: 1 results

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37. 岡本瑞穂 (90964148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. YAMASHITA fumiyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
39. TO Seikon

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. INOUE Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. KANEMARU Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. MAKIYAMA Takeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 志賀孝宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 御子柴克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 桜井正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 小比類巻生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 堀江稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
48. 小山田英人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 小口勝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 飯野正光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 宮野加奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 上園保仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 山口啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 井関雅子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUREBAYASHI Nagomi 呉林 なごみ

KUREBAYASHI Kunihiro 國廣 なごみ

国廣 なごみ クニヒロ ナゴミ

KUNIHIRO-KUREBAYASHI Nag 国広 なごみ

呉林 なごみ クレバヤシ ナゴミ

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Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agentsPrincipal Investigator

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Effectiveness of RyR2 inhibitors as antiarrhytmic drugsPrincipal Investigator

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Establishment of analysis method of ryanodine receptor arrhythmogenic mutations and its application to therapeutic drug screeningPrincipal Investigator

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興奮伝導・不整脈発生における心筋組織の細胞間不均一性の関与Principal Investigator

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KUREBAYASHI Nagomi 呉林なごみ

KUREBAYASHI Kunihiro 國廣なごみ

国廣なごみクニヒロナゴミ

KUNIHIRO-KUREBAYASHI Nag 国広なごみ

呉林なごみクレバヤシナゴミ