• Search Research Projects
  • Search Researchers
  1. Back to previous page

OBA Toshiharu  大羽 利治

ORCIDConnect your ORCID iD *help
Researcher Number 50008330
Other IDs
Affiliation *help 2014 : 中部大学, 応用生物学部, 教授
2007 : Nagoya City University, Graduate School of Medical Sciences, Departments of Cell Physiology, Associate professor
2005 – 2006 : 名古屋市立大学, 医学部, 助教授
1996 – 2001 : 名古屋市立大学, 医学部, 助教授
1992 : 名古屋市立大学, 医学部, 助教授
1988 – 1990 : 名古屋市立大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General physiology / Neurophysiology and muscle physiology
Except Principal Investigator
General pharmacology / Pediatrics
Keywords
Principal Investigator
筋小胞体 / システイン残基 / 活性酸素 / single channel current / SH基 / Caチャネル蛋白質 / シアニン系蛍光色素 / Ca チャネル / 骨格筋 / Transverse Tubule … More / ETH1001 / アデニンヌクレオチド / redox response / Voltage Sensor / Caチャネル / 膜電位 / 蛍光強度 / Ca channel protein / 二重マニト-ル間隙法 / チャネル活性 / 酸化剤 / Sulfhydryl Group / カルシウムチャネル電流 / グルタンチオン / 横行小管 / redox potential / cysteine residue / 骨格筋繊維 / チャネル電流 / 骨格筋skinned fiber / SH基の酸化・還元 / 筋の局所的損傷 / 骨格筋膜電位 / PH160 / シングルチャネル活性 / シングルチャネル電流 / Caチャンネル蛋白質 / ストレプトアビジン / Skeletal Muscle / 酸化・還元 / Ca Channel Protein / cysteineresidue / 骨格筋単収縮 / ビオチン / 酸化・還元電位 / チャネル修飾剤 / リアノジン受容体 / 情報伝達 / Ryanodine receptor / RH160 / 筋小胞体カルシウム遊離チャネル / 骨格筋横行小管 / 膜電位センサ- / カタラーゼ / Ca電極 / Streptavidin / 酸化還元電位 / Fluorescence Dye / L型Ca^<2+>チャネル … More
Except Principal Investigator
カルシウムイオン / 筋小胞体 / リアノジン受容体 / 膜電位 / 骨格筋 / cardiac hypertrophy / クレアチンキナーゼ / カルシウム / calcium ion / 細胞内Ca2+ / Myopathy / Animal model / heart failure / Skeletal muscle / S4-S5リンカー / 相互作用 / クレアチン キナーゼ / 心肥大 / Membrane potential / モデル動物 / 活動電位 / Calcium / sarcoplasmic reticulum / 人工アミノ酸 / ryanodine receptor / Creatine kinase / 細胞内カルシウム / カルシウムチャネル / 心不全 / Action potential / ミオパチー / カルモジュリン / 不整脈 / 興奮収縮連関 / Ionized calcium Less
  • Research Projects

    (8results)
  • Research Products

    (8results)
  • Co-Researchers

    (8People)
  •  Elucidation of regulatory mechanisms of type 2 ryanodine receptors by introducing artificial amino acids

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  Molecular mechanisms underlying abnormal functions in RyR2 complex in cardiac hypertrophy/heart failure

    • Principal Investigator
      MURAYAMA Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Juntendo University
  •  DO CYSTEINES LOCATED NEAR THE CHANNEL PORE OF THE RYANODINE RECEPTOR FUNCTION AS TARGET AMINO ACID FOR REACTIVE OXYGEN SPECIES?Principal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      NAGOYA GITY UNIVERSITY
  •  Study on the genetic mechanism underlying "hypocalcemic myopathy" using an animal model

    • Principal Investigator
      ISHIKAWA Tatsuya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Nagoya City University
  •  CYSTEIN CONFORMATIONAL CHANGES ARE ASSOCIATED WITH INACTIVATION OF L-TYPE CALCIUM CHANNELPrincipal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Nagoya City University
  •  活性酸素が生理条件下で筋損傷を発現する可能性に関するチャネル分子レベルでの研究Principal Investigator

    • Principal Investigator
      大羽 利治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Nagoya City University
  •  骨格筋興奮-収縮連関と膜電位センサーの酸化還元反応の関与に関する電気生理学的研究Principal Investigator

    • Principal Investigator
      大羽 利治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Institution
      Nagoya City University
  •  Coupling of Action Potential of T-Tubule with Ca^<2+> Release form Sarcoplasmic Reticulum in Skeletal MusclePrincipal Investigator

    • Principal Investigator
      OBA Toshiharu
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Nagoya City University

All 2014 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] Multifunctional GFP Tag2014

    • Author(s)
      Murayama T, Kobayashi T
    • Journal Title

      Methods Mol Biol

      Volume : 1177 Pages : 151-161

    • DOI
      10.1007/978-1-4939-1034-2_12
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590330
  • [Journal Article] Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca2+release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, Toshiharu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Journal Article] Cellular redox state protects acetaldchyde-induced alteration in cardiomyocyte function by modifying Ca2+ release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, Toshiharu
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 294

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Journal Article] Cellular redox state protects acetaldehyde-induced alteration in cardiomyocyte function by modifying Ca^<2+> release from sarcoplasmic reticulum2008

    • Author(s)
      Oba, T
    • Journal Title

      Am J Physiol Heart Circ Physiol 294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Generation of the GFP-tagged type 1 ryanodine receptor mutants by transposon-based random insertion approach2008

    • Author(s)
      Murayama, T, Kashiyama, T, Oyamada, H, Kobayashi, T, Kurebayashi, N, Sakurai, T
    • Organizer
      Biophysical Society 52nd Annual Meeting
    • Place of Presentation
      Long Beach, CA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] 1型リアノジン受容体ドメイン間相互作用により賦活されたチャネル活性に対する酸化の効果2007

    • Author(s)
      大羽 利治
    • Organizer
      第84回日本生理学会大会
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Role of a cytoplasmic loop between M7b and M8 transmembrane helices of RyR1 in Ca^<2+> channel gating2007

    • Author(s)
      Murayama, T, Oyamada, H, Oba, T, Oguchi, K, Kurebayashi, N
    • Organizer
      Biophysical Society 51st Annual Meeting
    • Place of Presentation
      Baltimore, MD
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • [Presentation] Postulated role of interdomain interactions within the type 1 ryanodine receptor in dysfunction of Ca^<2+> release channel in malignant hyperthermia2006

    • Author(s)
      Murayama, T, Oyamada, H, Kurebayashi, N, Oba, T, Hara, H, Wakebe, K, Ikemoto, N, Ogawa, Y
    • Organizer
      Biophysical Society 50th Annual Meeting
    • Place of Presentation
      Salt Laky City, UT
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590227
  • 1.  HOZUMI Tetsh (10080102)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 2.  MURAYAMA Takashi (10230012)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 4results
  • 3.  KUREBAYASHI Nagomi (50133335)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 3results
  • 4.  SAKAMOTO Kensaku (50240685)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 5.  MIURA Yutaka (90285198)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 6.  ISHIKAWA Tatsuya (80080117)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 7.  FUJIMOTO Shinji (60238615)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 8.  中郡 昭人 (50236824)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results

URL :

Are you sure that you want to connect your ORCID iD to this researcher?

Information FAQ News Terms of Use

Powered by NII kakenhi