HASHIDA Yasuhiko 橋田泰彦

Researcher Number	30512462
Affiliation (based on the past Project Information) *help	2013 – 2014: 京都大学, 物質-細胞統合システム拠点, 研究員 2010 – 2013: 京都大学, 物質-細胞統合システム拠点, 特定研究員 2012: 京都大学, 学内共同利用施設等, 研究員 2011: 京都大学, 物質‐細胞統合システム拠点, 特定研究員 2011: 京都大学, 物質細胞統合システム拠点, 特定研究員 2010 – 2011: 京都大学, 物質-細胞統合システム拠点, 研究員
Review Section/Research Field	Principal Investigator Physical pharmacy / Nanomaterials chemistry / Applied biochemistry Except Principal Investigator Applied pharmacology / Physical pharmacy / Biomedical engineering/Biological material science
Keywords	Principal Investigator ナノ材料 / ペプチド / カーボンナノチューブ / 薬剤放出 / 分子応答性 / 酸化還元酵素 / 薬物キャリア / 放出制御 / ドラッグデリバリー / 蛋白質工学 / タンパク質工学 / 酵素 … More Except Principal Investigator … More ドラッグデリバリー / 長期発現 / 遺伝子・細胞治療 / 細胞・遺伝子治療 / トランスポゾン / 遺伝子発現長期化 / 細胞治療 / TLR-4 / 炎症性サイトカイン / マクロファージ / 関節リウマチ / ヘパリンナノ粒子 / ターゲティング / ナノ粒子 / がん微小環境 / 超音波医科学 / ナノバイオ材料 / 小胞体ストレス / 免疫活性化 / がん治療 / 核酸医療 / 組織押圧核酸導入法 / in vivo長期遺伝子発現 / 遺伝子機能解析 / 組織核酸導入法 / phiC31インテグラーゼ / 長期遺伝子発現系 / 腎臓 / 肝臓 / 遺伝子デリバリー / 遺伝子導入 / 遺伝子治療 Less

Biomolecule-responsible nanocomposite for DDS applicationPrincipal Investigator
- Principal Investigator
  
  HASHIDA Yasuhiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials chemistry
  Physical pharmacy
- Research Institution
  Kyoto University
Therapeutic strategy of drug delivery systems utilizing unique tumor environment
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kyoto University
Development of heparin-based nanoparticles with multi-functional biological properties intended for rheumatoid arthritis therapy
- Principal Investigator
  
  YAMASHITA Fumiyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Long-term gene expression in primary cells by transposon and its application for cell therapy
- Principal Investigator
  
  HASHIDA Mitsuru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Development of long-term protein expression for medical application of gene delivery technology and its therapeutic application
- Principal Investigator
  
  KAWAKAMI Shigeru
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Formation of functional complex of enzymes with novel carbon nanotube/peptide compositePrincipal Investigator
- Principal Investigator
  
  HASHIDA Yasuhiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] ナノバイオ技術と最新創薬応用研究、第5章　ナノバイオ技術を応用した薬物・細胞動態の制御と評価2012
- Author(s)
  樋口ゆり子、橋田充
- Total Pages
  6
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23659284
[Book] ナノバイオ技術と最新創薬応用研究第5 章ナノバイオ技術を応用した薬物・細胞動態の制御と評価2012
- Author(s)
  樋口ゆり子、橋田充、メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23659284
[Journal Article] Journal of Controlled Release2014
- Author(s)
  Hashida, Y., Tanaka, H., Zhou, S., Kawakami, S., Yamashita, F., Murakami, T., Umeyama, T., Imahori, H., Hashida, M.
- Journal Title
  
  Photo thermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite
  
  Volume: 173 Pages: 59-66
- DOI
  10.1016/j.jconrel.2013.10.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300162, KAKENHI-PUBLICLY-25102518, KAKENHI-PROJECT-25870366, KAKENHI-PUBLICLY-25104514
[Journal Article] Tumour-associated macrophages targeted transfection with NF-kappaB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice2014
- Author(s)
  Y. Kono, S. Kawakami, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  J. Drug Targeting
  
  Volume: (in press) Issue: 5 Pages: 439-449
- DOI
  10.3109/1061186x.2014.880443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072, KAKENHI-PUBLICLY-25114705
[Journal Article] <i>In Vitro</i> Evaluation of Inhibitory Effect of Nuclear Factor-KappaB Activity by Small Interfering RNA on Pro-tumor Characteristics of M2-Like Macrophages2014
- Author(s)
  Y. Kono, S. Kawakami, Y. Higuchi, F. Yamashita, M. Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 1 Pages: 137-144
- DOI
  10.1248/bpb.b13-00659
- NAID
  130003382116
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072, KAKENHI-PROJECT-23689003
[Journal Article] Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex <i>via</i> Activation of Unfolded Protein Response2014
- Author(s)
  K. Matsumura, C. Sakai, S. Kawakami, F. Yamashita, M. Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 4 Pages: 648-653
- DOI
  10.1248/bpb.b13-00930
- NAID
  130003390969
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072
[Journal Article] Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice2013
- Author(s)
  M. Ikemura, M. Nishikawa, K. Kusamori, M. Fukuoka, F. Yamashita, M. Hashida
- Journal Title
  
  J. Controlled Release
  
  Volume: 170(2) Issue: 2 Pages: 191-197
- DOI
  10.1016/j.jconrel.2013.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072
[Journal Article] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2012
- Author(s)
  K. Un, Y. Kono, F. Yamashita, S. Kawakami, M.Hashida
- Journal Title
  
  Pharmazie
  
  Volume: 67(5) Pages: 400-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072
[Journal Article] Evaluation of long-term gene expression in mouse liver using phiC31 integrase and hydrodynamic injection2012
- Author(s)
  Y.Umemoto, S.Kawakami, Y.Otani, Y.Higuchi, F.Yamashita, M.Hashida
- Journal Title
  
  Biological and Pharmaceutial Bulletin
  
  Volume: (印刷中)
- NAID
  130001872117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] Efficient suppression of murine ICAM-1 using ultrasound-responsive and mannose-modified lipoplexes inhibits acute hepatic inflammation2012
- Author(s)
  Keita Un, Shigeru Kawakami, Mitsuru Yoshida, Yuriko Higuchi, Ryo Suzuki, Kazuo Maruyama, Fumiyoshi Yamashita, Mitsuru Hashida
- Journal Title
  
  Hepatology
  
  Volume: (in press) Issue: 1 Pages: 259-269
- DOI
  10.1002/hep.25607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01875, KAKENHI-PUBLICLY-23114506, KAKENHI-PROJECT-23240072, KAKENHI-PROJECT-23500567, KAKENHI-PROJECT-23689003
[Journal Article] Development of a Novel Composite Material with Carbon Nanotubes Assisted by Self-Assembled Peptides Designed in Conjunction withβ-Sheet Formation2012
- Author(s)
  Yasuhiko Hashida, Tomokazu Umeyama
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: (in press) Issue: 9 Pages: 3398-3412
- DOI
  10.1002/jps.23144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780090
[Journal Article] The involvement of NK cell activation following intranasal administration of CpG DNA lipoplex in the prevention of pulmonary metastasis and peritoneal dissemination in mice2012
- Author(s)
  Shuwen Zhou・Shigeru Kawakami・Yuriko Higuchi・Fumiyoshi Yamashita・Mitsuru Hashida
- Journal Title
  
  Clinical and Experimental metastasis
  
  Volume: 29 Issue: 1 Pages: 63-70
- DOI
  10.1007/s10585-011-9429-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02743, KAKENHI-PROJECT-23240072
[Journal Article] Creation of pure nanodrugs and their anticancer properties2012
- Author(s)
  H. Kasai, T. Murakami, Y. Ikuta, Y. Koseki, K. Baba, H. Oikawa, H. Nakanishi, M. Okada, M. Shoji, M. Ueda, H. Imahori, M. Hashida
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 51 Issue: 41 Pages: 10315-10318
- DOI
  10.1002/anie.201204596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240072, KAKENHI-PROJECT-23658098, KAKENHI-PROJECT-24300162, KAKENHI-PROJECT-24650263, KAKENHI-PROJECT-24688011
[Journal Article] Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells2011
- Author(s)
  Nakanishi H, Higuchi Y, Kawakami S, Yamashita F, Hashida M
- Journal Title
  
  Journal of biotechnology
  
  Volume: 154 Issue: 4 Pages: 205-208
- DOI
  10.1016/j.jbiotec.2011.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J01309, KAKENHI-PROJECT-23659284
[Journal Article] Comparison of piggyBac transposition efficiency between linear and circular donor vectors in mammalian cells.2011
- Author(s)
  Hideyuki Nakanishi, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita and Mitsuru Hashida
- Journal Title
  
  Journal of Biotechnology
  
  Volume: Vol.154 、No.4 Pages: 205-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659284
[Journal Article] Key physiological phenomena governing transgene expression based on tissue pressure-mediated transfection in mice2010
- Author(s)
  H.Mukai, S.Kawakami, H.Takahashi, Y.Otani, K.Satake, F.Yamashita, M.Hashida
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33(9) Pages: 1627-1637
- NAID
  130000322368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] Key Physiological Phenomena Governing Transgene Expression Based on Tissue Pressure-Mediated Transfection in Mice2010
- Author(s)
  Hidefumi Mukai, Shigeru Kawakami, Haruyuki Takahashi, Yuki Otani, Kyosuke Satake, Fumiyoshi Yamashita, and Mitsuru Hashida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 33 Issue: 9 Pages: 1627-1632
- DOI
  10.1248/bpb.33.1627
- NAID
  130000322368
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Journal Article] Evaluation of long-term gene expression in mouse liver using phiC31 integrase and hydrodynamic injection
- Author(s)
  Yoshiaki Umemoto, Shigeru Kawakami, Yuki Otani, Yuriko Higuchi, Fumiyoshi Yamashita, and Mitsuru Hashida
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: (in press)
- NAID
  130001872117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659110
[Patent] カーボンナノチューブ-ペプチド複合体2011
- Inventor(s)
  橋田泰彦、橋田充、樋口ゆり子、今堀博、梅山有和、磯田正二、辻本将彦
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2011-068972
- Filing Date
  2011-03-25
- Data Source
  KAKENHI-PROJECT-22780090
[Patent] 導入対象物質の送達装置の作動方法および導入対象物質の送達方法2010
- Inventor(s)
  清水一憲、小西聡、川上茂、橋田充
- Industrial Property Rights Holder
  京都大学、立命館大学
- Industrial Property Number
  2010-238885
- Filing Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] カーボンナノチューブを自己組織化的に被覆するペプチド分散剤の設計2015
- Author(s)
  橋田泰彦, 梅山有和, 三原潤也, 今堀博, 辻本将彦, 磯田正二, 高野幹夫, 橋田充
- Organizer
  生化学会近畿支部例会
- Place of Presentation
  滋賀県草津市
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-25870366
[Presentation] スフィンゴシン結合両親媒性ヘパリンによるナノ粒子の調整と物性評価2013
- Author(s)
  福岡美帆、Hasan Babazada、山下富義、橋田　充
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] マンノース６リン酸受容体を標的としたがん細胞指向性新規糖修飾リポソームの開発2013
- Author(s)
  松田顕也、川上茂、安藤弘宗、樋口ゆり子、山下富義、木曽真、橋田充
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Mechanisms of anti-inflammatory effect of heparin-sphingosine nanoparticles in activated macrophages in vitro2013
- Author(s)
  Hasan Babazada、福岡美帆、山下富義、橋田充
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] NF-kB decoyの腫瘍関連マクロファージ選択的DDSの開発：TAM phenotypeの再分化の誘導評価2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Inhibition of tumor growth by NF-kappaB decoy transfection into TAM using mannose-modified bubble lipoplexes in mice2013
- Author(s)
  河野裕允、川上茂、鈴木亮、丸山一雄、橋田充
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Inhibition of tumor growth by NF-κ B decoy transfection into TAM using mannose-modified bubble lipoplexes in mice2013
- Author(s)
  河野裕允、川上茂、鈴木亮、丸山一雄、橋田充
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] スフィンゴシン結合両親媒性ヘパリンによるナノ粒子の調整と物性評価2013
- Author(s)
  福岡美帆、 Hasan Babazada、山下富義、橋田充
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] Mechanisms of anti-inflammatory effect of heparin-sphingosine nanoparticles in activated macrophages in vitro2013
- Author(s)
  Hasan Babazada、福岡美帆、山下富義、橋田　充
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] Ultrasound triggered doxorubicin loaded microbubbles for effective therapeutic outcomes in melanoma2013
- Author(s)
  R. Abdalkader, M. Hashida, S. Kawakami, R. Suzuki, K. Maruyama
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Ultrasound triggered doxorubicin loaded microbubbles for effective therapeutic outcomes in melanoma2013
- Author(s)
  Rodi Abdalｋader, Mitsuru Hashida, Shigeru Kawakami, Ryo Suzuki, Kazuo Maruyama
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] マンノース修飾バブルリポソームを用いたNF-kappaB 活性制御による腫瘍関連マクロファージのphenotype 変化2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち(愛知県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] マンノース修飾バブルリポソームを用いたNF-kappaB活性制御による腫瘍関連マクロファージのphenotype変化2013
- Author(s)
  河野裕允、川上茂、樋口ゆり子、鈴木亮、丸山一雄、山下富義、橋田充
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] New Drug Delivery Systems2012
- Author(s)
  M. Hashida
- Organizer
  3rd International Regulatory Workshop on A to Z on Bioequivalence
- Place of Presentation
  The Hungarian Academy of Sciences, Budapest, Hungary
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Immunosuppressive effect of heparin nanoparticles on activated macrophages in primary culture2012
- Author(s)
  Hasan Babazada, Miho Fukuoka, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第27回日本薬物動態学会年会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] phiC31インテグラーゼを用いたマウス肝臓でのHGF発現の長期持続化と肝線維症治療効果の評価2012
- Author(s)
  梅本佳昭、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会13年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 配列選択的 DNA 結合蛋白質を用いた位置選択的遺伝子組込み型ベクターの開発2012
- Author(s)
  中西秀之、樋口ゆり子、川上茂、山下富義、橋田充
- Organizer
  第28回日本 DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] カーボンナノチューブへのアルカリホスファターゼの固定化2012
- Author(s)
  橋田泰彦、梅山有和、今堀博、橋田充
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22780090
[Presentation] カーボンナノチューブへのアルカリホスファターゼの固定化2012
- Author(s)
  橋田泰彦、梅山有和、今堀博、橋田充
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学(京都)
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22780090
[Presentation] NF-kB を標的とする抑制性オリゴ核酸による癌微小環境中のマクロファージの免疫再賦活化2012
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Place of Presentation
  仙台市民会館(宮城県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] 哺乳類細胞におけるpiggyBacトランスポゾンを用いた遺伝子組込みに対してベクターの設計並びに投与量が与える影響2012
- Author(s)
  中西秀之、樋口ゆり子、川上　茂、山下富義、橋田　充
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] 哺乳類細胞におけるpiggyBac トランスポゾンを用いた遺伝子組込みに対してベクターの設計並びに投与量が与える影響2012
- Author(s)
  中西秀之、樋口ゆり子、川上茂、山下富義、橋田充
- Organizer
  第35回日本分子生物学会年会、
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] GRP78 siRNAリポプレックスによるがん細胞アポトーシスの誘導と抗がん剤耐性の克服2012
- Author(s)
  松村一史、川上茂、山下富義、橋田充
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] New Drug Delivery Systems2012
- Author(s)
  Mitsuru Hashida
- Organizer
  3rd International Regulatory Workshop on A to Z on Bioequivalence
- Place of Presentation
  The Hungarian Academy of Sciences (Budapest, Hungary)
- Invited
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] phiC31インテグラーゼを用いたマウス肝臓でのHGF発現の長期持続化と肝線維症治療効果の評価2012
- Author(s)
  梅本佳昭、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 配列選択的DNA結合蛋白質を用いた位置選択的遺伝子組込み型ベクターの開発2012
- Author(s)
  中西秀之、樋口ゆり子、川上　茂、山下富義、橋田　充
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] 薬物治療とドラッグデリバリーシステム2012
- Author(s)
  橋田充
- Organizer
  薬工連携セミナー
- Place of Presentation
  立命館大学びわこくさつキャンパス(滋賀県)
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] NF-ｋBを標的とする抑制性オリゴ核酸による癌微小環境中のマクロファージの免疫再賦活化2012
- Author(s)
  河野裕允、川上茂、樋口ゆり子、山下富義、橋田充
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム２０１２
- Place of Presentation
  仙台市民会館（宮城県）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] ヘパリンナノパーティクルの物性及び免疫抑制効果の検討2012
- Author(s)
  Hasan Babazada、福岡美帆、山下富義、橋田充
- Organizer
  日本薬物動態学会第27 年会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-23659022
[Presentation] Evalution of the inhibition of NF-κB activity by using decoy oligonucleotides on the immune response of macrophages cultured in various cancer cells conditioned medium2012
- Author(s)
  Yusuke Kono, Shigeru Kawakami, Yuriko Higuchi, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  第6回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  京都大学薬学部（京都府）
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] phiC31 integrase-mediated long-term gene expression in the cultured renal cell lines and murine kidney2011
- Author(s)
  Shigeru Kawakami, Yuki Otani, Hidefumi Mukai, Yoshiaki Umemoto, Fumiyoshi Yamashita, and Mitsuru Hashida
- Organizer
  AMERICAN SOCIETY of GENE & CELL THERAPY(ASGCT)
- Place of Presentation
  シアトル(アメリカ合衆国)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] New technologies impacting drug discovery2011
- Author(s)
  橋田充
- Organizer
  World Congress of Pharmacy and Pharmaceutical Sciences 2011
- Place of Presentation
  ハイデラバード(インド)
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] ペプチドを用いて分散されたカーボンナノチューブを利用した光線温熱効果の検討2011
- Author(s)
  田中宏則, 周舒文, 橋田泰彦, 川上茂, 梅山有和, 村上達也, 今堀博, 山下富義, 橋田充
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22780090
[Presentation] phiC31 integrase-mediated long-term gene expression in the cultured renal cell lines and murine kidney2011
- Author(s)
  S.Kawakami, Y.Otani, H.Mukai, Y.Umemoto, F.Yamashita, M.Hashida
- Organizer
  AMERICAN SOCIETY of GENE & CELL THERAPY (ASGCT) 14th Annual Meeting
- Place of Presentation
  シアトル(アメリカ合衆国)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] ペプチドを用いて分散されたカーボンナノチューブを利用した光線温熱効果の検討2011
- Author(s)
  田中宏則、周舒文、橋田泰彦、川上茂、梅山有和、村上達也、今堀博、山下富義、橋田充
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22780090
[Presentation] Development of piggyBac transposon-based vector system for long-term gene expression.2011
- Author(s)
  Hideyuki Nakanishi, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  The 6th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  Seoul (Korea)
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] Evalustion of endosomal escape of lysine-histidine dendrons by live cell imaging2011
- Author(s)
  Yuriko Higuchi, Kai-ling Chang, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場(広島県)
- Data Source
  KAKENHI-PROJECT-23240072
[Presentation] Development of piggyBac transposon-based vector system for long-term gene expression2011
- Author(s)
  Hideyuki Nakanishi, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita, Mitsuru Hashida
- Organizer
  The 6th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  Seoul (Korea)
- Data Source
  KAKENHI-PROJECT-23659284
[Presentation] Gaussia luciferaseを用いたφC31 integraseによるin vivo長期遺伝子発現の簡便な評価法の開発2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] φC31 integraseによるin vivo長期遺伝子発現の簡便な評価を目的とした分泌型luciferase発現pDNAの構築2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー
- Place of Presentation
  琵琶湖ホテル(滋賀)
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] φC31 integraseによるin vivo長期遺伝子発現の簡便な評価を目的とした分泌型luciferase発現pDNAの構築2010
- Author(s)
  梅本佳昭、川上茂、大谷祐基、山下富義、橋田充
- Organizer
  遺伝子・デリバリー研究会第10回夏期セミナー、琵琶湖ホテル(滋賀)
- Place of Presentation
  琵琶湖ホテル(滋賀)
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 臓器特異的遺伝子発現制御を目的とする組織押圧核酸導入法の開発と評価2010
- Author(s)
  向井英史、川上茂、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 臓器特異的遺伝子発現制御を目的とする組織押圧核酸導入法の開発と評価2010
- Author(s)
  向井英史、川上茂、橋田充
- Organizer
  第60回日本薬学会近畿支部会
- Place of Presentation
  摂南大学(大阪)(招待講演)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22659110
[Presentation] 薬物治療とドラッグデリバリーシステム
- Author(s)
  橋田　充
- Organizer
  薬工連携セミナー
- Place of Presentation
  立命館大学びわこくさつキャンパス（滋賀県）
- Invited
- Data Source
  KAKENHI-PROJECT-23659284

1. HIGUCHI Yuriko (40402797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. KAWAKAMI Shigeru (20322307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
3. HASHIDA Mitsuru (20135594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
4. YAMASHITA Fumiyoshi (30243041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. UMEYAMA Tomokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 田中元雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 村上達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HASHIDA Yasuhiko 橋田 泰彦

Research Projects

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Co-Researchers

Biomolecule-responsible nanocomposite for DDS applicationPrincipal Investigator

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Therapeutic strategy of drug delivery systems utilizing unique tumor environment

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Development of heparin-based nanoparticles with multi-functional biological properties intended for rheumatoid arthritis therapy

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Long-term gene expression in primary cells by transposon and its application for cell therapy

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Development of long-term protein expression for medical application of gene delivery technology and its therapeutic application

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Formation of functional complex of enzymes with novel carbon nanotube/peptide compositePrincipal Investigator

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[Book] ナノバイオ技術と最新創薬応用研究、第5章 ナノバイオ技術を応用した薬物・細胞動態の制御と評価2012

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[Book] ナノバイオ技術と最新創薬応用研究第5 章ナノバイオ技術を応用した薬物・細胞動態の制御と評価2012

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[Journal Article] Journal of Controlled Release2014

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[Journal Article] Tumour-associated macrophages targeted transfection with NF-kappaB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice2014

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[Journal Article] <i>In Vitro</i> Evaluation of Inhibitory Effect of Nuclear Factor-KappaB Activity by Small Interfering RNA on Pro-tumor Characteristics of M2-Like Macrophages2014

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[Journal Article] Inhibition of Cancer Cell Growth by GRP78 siRNA Lipoplex <i>via</i> Activation of Unfolded Protein Response2014

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[Journal Article] Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice2013

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[Journal Article] Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes2012

HASHIDA Yasuhiko 橋田泰彦

[Book] ナノバイオ技術と最新創薬応用研究、第5章　ナノバイオ技術を応用した薬物・細胞動態の制御と評価2012