NAKAMURA HIROYUKI 中村博幸

… Alternative Names

NAKAMURA Hiroyuki 中村博幸

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Researcher Number	30542253
Other IDs
External Links
Affiliation (Current)	2022: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 琉球大学, 大学院医学研究科, 教授 2013 – 2019: 金沢大学, 医学系, 准教授 2012: 独立行政法人国立長寿医療研究センター, 再生歯科医療研究部, 副部長 2011: 国立長寿医療研究センター, 再生歯科医療研究部, 副部長 2010: Tokyo Medical and Dental University, その他 2009 – 2010: Tokyo Medical and Dental University, 歯と骨のGCOE拠点, GCOE拠点形成特任教員
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Experimental pathology / Surgical dentistry Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator MMP / 癌幹細胞 / TIMP3 / ADAM / 歯髄炎 / MMP-3 / バーシカン / PD-L1 / 口腔癌 / 臨床腫瘍 … More Except Principal Investigator … More 口腔扁平上皮癌 / 顎変形症 / 気道通気状態 / 睡眠呼吸障害 / ポリソムノグラフィー / 周術期管理 / 睡眠時咬筋活動 / 気道 / 顎矯正手術 / 上気道通気状態 / CT / PSG / 浸潤 / 転移 / 間質 / 微小環境 / 増殖 / 腫瘍間質 / 微小管阻害薬 / 口腔癌 / 微小管 / 臨床腫瘍 / 進行性下顎頭吸収 / STR/ortマウス / STR/Ortマウス / -1AlaTIMP3 / STR / Ortマウス / TMJ-OA / アグリカナーゼ / [-1A] TIMP-3 / 下顎頭軟骨 / 保護 / 野生型Str/Ortマウス / 病態 / 発症原因 Less

Elucidation of the pathophysiology and cause of progressive mandibular condylar resorption
- Principal Investigator
  
  Ooi Kazuhiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kanazawa University
Analysis of Tumor Immunosuppressive Mechanisms in the Oral Cancer Invasive Microenvironment.Principal Investigator
- Principal Investigator
  
  Nakamura Hiroyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanazawa University
Association analysis of microtubules and the mechanism of highly invasive acquisition in oral cancer
- Principal Investigator
  
  Kitahara Hiroko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanazawa University
Evaluation of perioperative obstructive sleep apnea in patient with dentofacial deformity
- Principal Investigator
  
  OOI Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanazawa University
Explication of mechanisms on invasion and metastasis, and prevention of invasion and metastasis of oral squamous cell carcinoma
- Principal Investigator
  
  Kawashiri Shuichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kanazawa University
Anti-inflammatory effect of MMP-3 on tissue regeneration in dental pulpitis.Principal Investigator
- Principal Investigator
  
  nakamura hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kanazawa University
The role of extracellular matrix degradation enzymes, MMP and ADAM in tumor micro environment (stem cell niche)Principal Investigator
- Principal Investigator
  
  NAKAMURA Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  National Center for Geriatrics and Gerontology
  Tokyo Medical and Dental University
癌幹細胞微小環境(ニッチ)におけるMMPおよびADAMの役割検討Principal Investigator
- Principal Investigator
  
  中村博幸
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] メタロプロテアーゼ関節リウマチ(寛解を目指す治療の新時代)第2版2010
- Author(s)
  中村博幸、岡田保典
- Publisher
  日本臨床増刊
- Data Source
  KAKENHI-PROJECT-22592030
[Book] 炎症メディエーターメタロプロテアーゼ2010
- Author(s)
  中村博幸, 岡田保典
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] Metalloelastase?12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice2021
- Author(s)
  Yamashita-futani Yoko、Jokaji Rei、Ooi Kazuhiro、Kobayashi Kazuhiko、Kanakis Ioannis、Liu Ke、Kawashiri Shuichi、Bou-gharios George、Nakamura Hiroyuki
- Journal Title
  
  Biomedical Reports
  
  Volume: 14 Pages: 1-8
- DOI
  10.3892/br.2021.1427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09764, KAKENHI-PROJECT-21K10135
[Journal Article] Selectively high efficacy of Eribulin against high-grade invasive recurrent and /or metastatic squamous cell carcinoma of the head and neck.2019
- Author(s)
  Kobayashi Yutaka、Kitahara Hiroko、Hirai Mariko、Tanaka Akira、Jokaji Rei、Kobayashi Kazuhiko、Bou?Gharios George、Nakamura Hiroyuki、Kawashiri Shuichi
- Journal Title
  
  Oncol Lett.
  
  Volume: 17 Pages: 5064-5072
- DOI
  10.3892/ol.2019.10165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11869, KAKENHI-PROJECT-17K11870, KAKENHI-PROJECT-18K17221
[Journal Article] Clinicopathological Significace of the ET Axis in Human Oral Squamous Cell Carcinoma.2019
- Author(s)
  Miyazawa H, Kato K, Kobayashi Y, Hirai M, Kimura I, Kitahara H, Noguchi N, Nakamura H, Kawashiri S
- Journal Title
  
  Pathol Oncol Res.
  
  Volume: 25(3)
- DOI
  10.1007/s12253-018-0514-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11870
[Journal Article] Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage2018
- Author(s)
  Hira-Miyazawa M, Nakamura H, Hirai M, Kobayashi Y, Kitahara H, Bou-Gharios G, Kawashiri S.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 379-388
- DOI
  10.3892/ijo.2017.4221
- NAID
  130007595071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-17K11869, KAKENHI-PROJECT-17K11870, KAKENHI-PROJECT-18K17221, KAKENHI-PROJECT-19K21394
[Journal Article] Ointment vehicles regulate the wound‐healing process by modifying the hyaluronan‐rich matrix2018
- Author(s)
  Murasawa Yusuke、Furuta Katsunori、Noda Yasuhiro、Nakamura Hiroyuki、Fujii Satoshi、Isogai Zenzo
- Journal Title
  
  Wound Repair and Regeneration
  
  Volume: 26 Pages: 437-445
- DOI
  10.1111/wrr.12673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11869
[Journal Article] Higher Blood Vitamin C Levels are Associated with Reduction of Apolipoprotein E E4-related Risks of Cognitive Decline in Women: The Nakajima Study2018
- Author(s)
  Noguchi-Shinohara M, Abe C, Yuki-Nozaki S, Domoto C, Mori A, Hayashi K, Shibata S, Ikeda Y, Sakai K, Iwasa K, Yokogawa M, Ishimiya M, Nakamura H, Yokoji H, Komai K, Nakamura H, Yamada M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 63 Pages: 1289-1297
- DOI
  10.3233/jad-170971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-17K11869
[Journal Article] Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study2018
- Author(s)
  Ishimiya Mai、Nakamura Hiroyuki、Kobayashi Yutaka、Noguchi-Shinohara Moeko、Abe Chiemi、Dohmoto Chiaki、Ikeda Yoshihisa、Tokuno Kahori、Ooi Kazuhiro、Yokokawa Masami、Iwasa Kazuo、Komai Kiyonobu、Kawashiri Shuichi、Yamada Masahito
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Pages: 0194504-0194504
- DOI
  10.1371/journal.pone.0194504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09795, KAKENHI-PROJECT-17K11869
[Journal Article] The Versican G1 Fragment and Serum-Derived Hyaluronan-Associated Proteins Interact and Form a Complex in Granulation Tissue of Pressure Ulcers2018
- Author(s)
  Murasawa Yusuke、Nakamura Hiroyuki、Watanabe Ken、Kanoh Hiroyuki、Koyama Emiko、Fujii Satoshi、Kimata Koji、Zako Masahiro、Yoneda Masahiko、Isogai Zenzo
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 188 Pages: 432-449
- DOI
  10.1016/j.ajpath.2017.10.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11869
[Journal Article] 56POral squamous cell carcinoma cells were sensitized to cetuximab by Eribulin via induction of the mesenchymal-to-epithelial transition2017
- Author(s)
  Kitahara H.、Hirai M.、Kawashiri S.、Nakamura H.
- Journal Title
  
  Annals of Oncology
  
  Volume: 28
- DOI
  10.1093/annonc/mdx361.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11869
[Journal Article] Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment2017
- Author(s)
  Hirai M, Kitahara H, Kobayashi Y, Kato K, Bou-Gharios G, Nakamura H, Kawashiri S.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 50 Pages: 41-48
- DOI
  10.3892/ijo.2016.3785
- NAID
  120005973600
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-26670861, KAKENHI-PROJECT-15K20510, KAKENHI-PROJECT-26463038, KAKENHI-PROJECT-17K11869
[Journal Article] Elastin-derived peptides are involved in the processes of human temporomandibular disorder by inducing inflammatory responses in synovial cells.2017
- Author(s)
  Kobayashi K, Jokaji R, Miyazawa-Hira M, Takatsuka S, Tanaka A, Ooi K, Nakamura H, Kawashiri S.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 16 Pages: 3147-3154
- DOI
  10.3892/mmr.2017.7012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05042
[Journal Article] 1721PThe role of PD-L1 in a high-grade invasive human oral squamous cell carcinoma microenvironment2017
- Author(s)
  Hirai M.、kitahara H.、Kobayashi Y.、Kawashiri S.、Nakamura H.
- Journal Title
  
  Annals of Oncology
  
  Volume: 28
- DOI
  10.1093/annonc/mdx391.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11869
[Journal Article] Loss of EGFR expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition.2016
- Author(s)
  Kimura I, Kitahara H, Ooi K, Kato K, Noguchi N, Yoshizawa K, Nakamura H, Kawashiri S.
- Journal Title
  
  Oncology Letters.
  
  Volume: 11 Pages: 201-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05042
[Journal Article] Eriburin sensitizes oral squamous cell carcinoma cells to cetuximab via induction of mesenchymal-to-epithelial transition2016
- Author(s)
  Kitahara H, Hirai M, Kato K, Bou-Gharios G, Nakamura H, Kawashiri S.
- Journal Title
  
  Oncology Reports
  
  Volume: 36 Pages: 3139-3144
- DOI
  10.3892/or.2016.5189
- NAID
  120005973603
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042, KAKENHI-PROJECT-26670861, KAKENHI-PROJECT-15K20510, KAKENHI-PROJECT-26463038
[Journal Article] 口腔扁平上皮癌におけるPD-L1発現の検討2016
- Author(s)
  平井真理子，中村博幸，川尻秀一
- Journal Title
  
  日本口腔組織培養学会雑誌
  
  Volume: 25 Pages: 11-12
- Data Source
  KAKENHI-PROJECT-15H05042
[Journal Article] Loss of epidermal growth factor receptor expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition.2016
- Author(s)
  Ito Kimura, Hiroko Kitahara, Kazuhiro Ooi, Koroku Kato, Natsuyo Noguchi, Kunio Yoshizawa, Hiroyuki Nakamura, Shuichi Kawashiri
- Journal Title
  
  Oncol Lett
  
  Volume: 11 Pages: 201-207
- DOI
  10.3892/ol.2015.3833
- NAID
  120005973602
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26463038, KAKENHI-PROJECT-26463039, KAKENHI-PROJECT-15K20510, KAKENHI-PROJECT-25462882
[Journal Article] Prognostic value of vascular endothelial growth factors A and C in oral squamous cell carcinoma2014
- Author(s)
  Yanase M., Kato K., Yoshizawa K., Noguchi N., Kitahara H., Nakamura H
- Journal Title
  
  Journal of Oral Pathology and Medicine
  
  Volume: (in press) Pages: 514-20
- DOI
  10.1111/jop.12167
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24792195, KAKENHI-PROJECT-25462882, KAKENHI-PROJECT-25861923, KAKENHI-PROJECT-26463038
[Journal Article] Generation of a mouse line harboring a bi-transgene expressing luciferase and tamoxifen-activatable creERT2 recombinase in cartilage2014
- Author(s)
  Leandro Lo Cascio, Ke Liu, Hiro Nakamura, Grace Chu, Ngee Han Lim, Anastasios Chanalaris, Jeremy Saklatvala, Hideaki Nagase andGeorge Bou-Gharios
- Journal Title
  
  genesis
  
  Volume: 52 Pages: 110-119
- DOI
  10.1002/dvg.22734
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462882
[Journal Article] The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teeth.2012
- Author(s)
  Eba, H., Murasawa, Y., Iohara, K., Isogai, Z., Nakamura, H., Nakamura, H. and Nakashima, M.
- Journal Title
  
  PloS one
  
  Volume: 7
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teeth.2012
- Author(s)
  Eba, H., Murasawa, Y., Iohara, K., Isogai, Z.,Nakamura, H., and Nakashima, M
- Journal Title
  
  PloS one
  
  Volume: 7
- DOI
  10.1371/journal.pone.0052523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] Microchimeric fetal cells are recruited to maternal kidney following injury and activate collagen type 1 transcription.2011
- Author(s)
  Hiroyuki Nakamura
- Journal Title
  
  Cells Tissues Organs
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] Microchimeric fetal cells are recruited to maternal kidney following injury and activate collagen type I transcription.2011
- Author(s)
  Bou-Gharios, G., Amin, F., Hill, P., Nakamura, H., Maxwell, P., and Fisk, NM.
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 193 Pages: 379-392
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] Microchimeric fetal cells are recruited to maternal kidney following injury and activate collagen type I transcription2011
- Author(s)
  Bou-Gharios G., Amin F., Hill P., Nakamura H., Maxwell P., Fisk NM
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 193 Pages: 379-392
- DOI
  10.1159/000321172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis.2010
- Author(s)
  Sonnylal, S., Shi-Wen, X., Leoni, P., Naff, K., Van Pelt, CS., Nakamura, H., Leask, A., Abraham, D., Bou-Gharios, G., and de Crombrugghe, B.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 62 Pages: 1523-1532
- Data Source
  KAKENHI-PROJECT-22592030
[Journal Article] The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-32009
- Author(s)
  Hiroyuki Nakamura
- Journal Title
  
  Matrix Biol 28
  
  Pages: 463-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890066
[Presentation] Temporomandibular joint osteoarthritis in the STR/Ort mouse model of spontaneous osteoarthritis and effect of targeted inhibition of aggrecanases for mandibular condylar cartilage degradation2019
- Author(s)
  Kazuhiro Ooi, Ioannis Kanakis, Yoko Yamashita, Hiroyuki Nakamura, Shuichi Kawashiri, George Bou-Gharios
- Organizer
  American Society for Temporomandibular Joint Surgeon Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09764
[Presentation] エリブリンの高浸潤性頭頸部癌に対する選択的高感受性の検討2019
- Author(s)
  小林泰，中村博幸，北原寛子，川尻秀一
- Organizer
  第43回頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] Effect of targeted inhibition of aggrecanases for mandibular condylar cartilage degradation in the STR/Ort spontaneous mouse model of temporomandibular joint osteoarthritis2019
- Author(s)
  OOI K, KANAKIS I, YAMASHITA Y, IDE K, FUTANI Y, KOBAYASHI Y, KOBAYASHI K, JOKAJI R, NAKAMURA H, YAMAMOTO K, SAKAI T, BOU-GHARIOS G, KAWASHIRI S
- Organizer
  The 6th Asian Academy congress for TMJ
- Data Source
  KAKENHI-PROJECT-18K09764
[Presentation] Perioperative Evaluation and Management of Obstructive Sleep Apnea after Mandibular Setback by Saggital Splitting Ramus Osteotomy2018
- Author(s)
  R.Jyokaji, K.Ooi, K.Ide, M.Ishimiya, Y.Kobayashi, H.Kitahara, N.Noguchi, K. katoh, H.Nakamura, S.Takamichi, M.Nakata, K.Kasahara, S.Kawashiri
- Organizer
  23rd International Conference on Oral and Maxillofacial Surgeon
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] The role of PD-L1 in a high-grade invasive human oral squamous cell carcinoma microenvironment.2017
- Author(s)
  Hirai M, Kitahara H, Kobayashi Y, Kawashiri S, Nakamura H
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEAUSING PERIPHERAL ARTERIAL TONOMETRY DURING PERIOPERATIVE PERIOD AFTER REMOVAL OF IMPACTED THIRD MOLAR WITH DENTOFACIAL DEFOTMITY IN GENERAL ANETHESIA2017
- Author(s)
  Y. Kobayashi, K. Ooi, R. Jyokaji, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, N. Nakata, T. Kasahara, S. Kawashiri
- Organizer
  International conference for oral and maxillofacial surgery 2017
- Place of Presentation
  香港
- Year and Date
  2017-03-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] Oral squamous cell carcinoma cells were sensitized to cetuximab by Eribulin via induction of mesenchymal-to-epithelial transition.2017
- Author(s)
  Kitahara H, Hirai M, Kobayashi Y, Nakamura H, Kawashiri S.
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] The role of PD-L1 in a high-grade invasive human oral squamous cell carcinoma microenvironment2017
- Author(s)
  Hirai M, Kitahara H, Kobayashi Y, Nakamura H, Kawashiri S
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] Oral Squamous cell carcinoma cells were sensitized to cetuximab by Eribulin via inducation of the mesenchymal-to-epithelial transition2017
- Author(s)
  Kitahara H, Hirai M, Kobayashi Y, Nakamura H, Kawashiri S
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA AND SLEEP QUALITY IN PATIENTS WITH SKELETAL CLASS Ⅲ MALOCCLUSION2017
- Author(s)
  K. Ooi, R. Jokaji, K. Ide, Y. Kobayashi, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
- Organizer
  International conference for oral and maxillofacial surgery 2017
- Place of Presentation
  香港
- Year and Date
  2017-03-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] 下顎前突症患者における周術期の閉塞性睡眠呼吸障害の評価とその予測因子2017
- Author(s)
  大井一浩，定梶嶺，井手健太郎，大矢明日香，小林泰，野口夏代，加藤広禄，中村博幸，川尻秀一
- Organizer
  日本口腔外科学会総会
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA USING PERIPHERAL ARTERIAL TONOMETRY DURING PERIOPERATIVE PERIOD AFTER REMOVAL OF IMPACTED THIRD MOLAR WITH DENTOFACIAL DEFOTMITY IN GENERAL ANETHESIA2017
- Author(s)
  Y. Kobayashi, K. Ooi, K. Ide, R. Jokaji, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri,
- Organizer
  International Conference of Oral and Maxillofacial Surgery 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] 口腔扁平上皮癌細胞のInvadopodia形成と癌関連線維芽細胞（CAF）との関連2017
- Author(s)
  加藤広禄、北原寛子、野口夏代、中村博幸、川尻秀一
- Organizer
  第42回日本頭頚部癌学会
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] PERIOPERATIVE EVALUATION AND MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA AFTER MANDIBULAR SETBACK BY SAGGITAL SPLITTING RAMUS OSTEOTOMY2017
- Author(s)
  R. Jokaji, K. Ooi, K. Ide, M. Ishimiya, Y. Kobayashi, H. Kitahara, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
- Organizer
  International conference for oral and maxillofacial surgery 2017
- Place of Presentation
  香港
- Year and Date
  2017-03-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] ヒト頭頸部扁平上皮癌細胞の細胞膜上でのMMPの分解によるPD-L1発現量調節機構2017
- Author(s)
  宮澤（平）真優子、中村博幸、川尻秀一
- Organizer
  第54回日本口腔組織培養学会学術大会総会
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] Oral squamous cell carcinoma cells were sensitized to cetuximab by Eribulin via inducation of the mesenchymal-to-epithelial transition.2017
- Author(s)
  Kitahara H., Hirai M., Kobayashi Y., Kawashiri S and Nakamura H.
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11869
[Presentation] The role of PD-L1 in a high-grade invasive human oral squamous cell carcinoma microenvironment.2017
- Author(s)
  Hirai M., Kitahara H., Kobayashi Y., Kawashiri S and Nakamura H.
- Organizer
  European Society for Medical Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11869
[Presentation] 口腔扁平上皮癌細胞のIndadopodia形成と癌関連線維芽細胞(CAF)との関連2017
- Author(s)
  加藤広禄、北原寛子、野口夏代、中村博幸、川尻秀一
- Organizer
  第41回頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] PERIOPERATIVE EVALUATION AND MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA AFTER MANDIBULAR SETBACK BY SAGGITAL SPLITTING RAMUS OSTEOTOMY2017
- Author(s)
  R. Jokaji, K. Ooi, K. Ide, M. Ishimiya, Y. Kobayashi, H. Kitahara, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
- Organizer
  International Conference of Oral and Maxillofacial Surgery 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] 舌に発生した平滑筋腫の1例2017
- Author(s)
  吉本泰祐、加藤広禄、本保敦志、北原寛子、大井一浩、中村博幸、川尻秀一
- Organizer
  第60回日本口腔科学会中部地方会
- Data Source
  KAKENHI-PROJECT-17K11870
[Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA AND SLEEP QUALITY IN PATIENTS WITH SKELETAL CLASS Ⅲ MALOCCLUSION2017
- Author(s)
  K. Ooi, R. Jokaji, K. Ide, Y. Kobayashi, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
- Organizer
  International Conference on Oral and Maxillofacial Surgery 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11310
[Presentation] Loss of EGFR expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition2016
- Author(s)
  Iyo Kimura, Hiroko Kitahara, Hiroyuki Nakamura, Shuichi Kawashiri;
- Organizer
  The Joint Meeting of 4th Congress of Asian Society of Head and Neck Oncology (ASHNO) and 39th Annual Meeting of Japan Society for Head and Neck Cancer (JSHNC)
- Place of Presentation
  kobe
- Year and Date
  2016-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] セツキシマブ非感受性口腔癌細胞でのエリブリンの作用検討2016
- Author(s)
  北原寛子，中村博幸，平井真理子，加藤広禄，川尻秀一
- Organizer
  第70回日本口腔科学会総会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] Loss of EGFR expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition2016
- Author(s)
  Hiroyuki Nakamura, Iyo Kimura, Hiroko Kitahara, Shuichi Kawashiri;
- Organizer
  European Cancer Congress 2015
- Place of Presentation
  Vienna.
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] 新規加工コラーゲンによる骨造成効果の検討2016
- Author(s)
  定梶嶺、中村博幸、川尻秀一
- Organizer
  第45回日本口腔インプラント学会学術大会
- Place of Presentation
  岡山
- Year and Date
  2016-09-22
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] 顎関節症滑膜炎におけるエラスチン分解産物の役割2016
- Author(s)
  中村博幸、小林一彦、田中彰、高塚茂之、川尻秀一
- Organizer
  第47回日本結合組織学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-05-15
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] 口腔扁平上皮癌におけるPD-L１発現の検討2016
- Author(s)
  平井真理子，北原寛子，中村博幸，川尻秀一
- Organizer
  第70回日本口腔科学会総会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] The regulation of PD-L1 expression at microenvironment of high grade invasive human oral squamous cell carcinoma2016
- Author(s)
  Hirai M, Kitahara K, Kimura I, Kato K, Bou-Gharios G, Nakamura H, Kawashiri S
- Organizer
  24th Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Manchester Central Convention Complex (UK)
- Year and Date
  2016-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] 口腔扁平上皮癌におけるEGFR発現と浸潤様式の相関と上皮間葉移行の関与2016
- Author(s)
  中村博幸、川尻秀一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2016-10-10
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] Eribulin differentiaes cetuximab resistant oral squamous cell carcinoma cells to senseitive by inducing mesenchymal-epithelial transition(MET)2016
- Author(s)
  Kitahara K, Hirai M, Nakamura H, Kawashiri S
- Organizer
  24th Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  Manchester Central Convention Complex (UK)
- Year and Date
  2016-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] 口腔扁平上皮癌細胞のInvadopodia 形成と癌関連線維芽細胞(CAF)との関連2016
- Author(s)
  加藤広禄，宮澤広樹，加藤阿希，平井真理子，吉本泰祐，木村依世，北原寛子，野口夏代，中村博幸，川尻秀一
- Organizer
  第61回日本口腔外科学会総会学術大会
- Place of Presentation
  幕張メッセ（千葉）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] 口腔扁平上皮癌におけるPD-L1発現の検討2015
- Author(s)
  平井真理子、中村博幸、川尻秀一
- Organizer
  第52回日本口腔組織培養学会学術大会
- Place of Presentation
  徳島大学（徳島）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] Loss of EGFR expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition.2015
- Author(s)
  Kimura I, Kitahara H, Nakamura H, Kawashiri S.
- Organizer
  The Joint Meeting of 4th Congress of Asian Society of Head and Neck Oncology and 39th Annual Meeting of Japan Society for Head and Neck Cancer
- Place of Presentation
  神戸国際会議場（兵庫）
- Year and Date
  2015-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] セツキシマブ非感受性口腔癌細胞株でのエルブリンの作用検討2015
- Author(s)
  北原寛子、木村依世、中村博幸、川尻秀一
- Organizer
  第60回日本口腔外科学会総会・学術大会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] 口腔扁平上皮癌におけるEGFR発現と浸潤様式の相関と上皮間葉移行の関与2015
- Author(s)
  中村博幸、川尻秀一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] Loss of EGFR expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition.2015
- Author(s)
  Nakamura H, Kimura I, Kitahara H, Kawashiri S.
- Organizer
  European Cancer Congress 2015
- Place of Presentation
  Messezentrum Vienna (Austria)
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] セツキシマブ非感受性口腔癌の解析と新しい治療法の検討2015
- Author(s)
  中村博幸、北原寛子、木村依世、川尻秀一
- Organizer
  第60回日本口腔外科学会総会・学術大会
- Place of Presentation
  名古屋国際会議場（愛知）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H05042
[Presentation] 不可逆性歯髄炎でのMMP-3の抗炎症、組織再生作用のメカニズム解析2013
- Author(s)
  中村博幸
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] MMP-3の抗炎症、組織再生作用の検討2013
- Author(s)
  中村博幸、川尻秀一
- Organizer
  第58回日本口腔外科学会学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25462882
[Presentation] 歯の再生医療2013
- Author(s)
  中村博幸
- Organizer
  平成25年度九州歯科大同窓会北陸支部学術講演会
- Place of Presentation
  福井
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] MMP-3 の歯髄炎での抗炎症, 組織再生作用の検討2012
- Author(s)
  中村博幸
- Organizer
  第10回日本再生歯科医学会（シンポジウムI）
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] MMP-3の歯髄炎での抗炎症, 組織再生作用の検討2012
- Author(s)
  中村博幸
- Organizer
  第10回日本再生歯科医学会(シンポジウムI)
- Place of Presentation
  神戸
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] 歯科再生医療の背景と最先端事情2012
- Author(s)
  中村博幸
- Organizer
  第22回金沢歯科口腔外科懇話会
- Place of Presentation
  金沢
- Year and Date
  2012-02-25
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] 歯の再生医療2012
- Author(s)
  中村博幸
- Organizer
  平成24年度九州歯科大東京都同窓会学術講演会
- Place of Presentation
  東京
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] 細胞外マトリックス分解最近の知見2011
- Author(s)
  中村博幸
- Organizer
  平成23年愛知医科大学分子医科学研究所フォーラム
- Place of Presentation
  愛知
- Year and Date
  2011-04-20
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] 細胞外マトリックス分解最近の知見2010
- Author(s)
  中村博幸
- Organizer
  第17回プロテオグリカンフォーラム
- Place of Presentation
  東京
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-22592030
[Presentation] 関節症における細胞外ラトリックス分解酵素の新たな役割2009
- Author(s)
  中村博幸
- Organizer
  第51回歯科基礎医学会
- Place of Presentation
  新潟
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21890066
[Presentation] 歯髄炎でのMMP-3の抗炎症、組織再生作用とバーシカンの役割
- Author(s)
  中村博幸、村澤裕介、平真優子、小林一彦、磯貝善蔵、川尻秀一
- Organizer
  第46回日本結合組織学術大会
- Place of Presentation
  愛知　ウインクあいち
- Year and Date
  2014-06-05 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25462882

1. OOI Kazuhiro (90451450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. Kitahara Hiroko (70507053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. Kawashiri Shuichi (30291371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
4. NOGUCHI Natsuyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. YOSHIZAWA Kunio

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 平井真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 宮澤真優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 加藤広禄

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. 山田正仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 篠原もえ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

NAKAMURA HIROYUKI 中村 博幸

NAKAMURA Hiroyuki 中村 博幸

Research Projects

Research Products

Co-Researchers

Elucidation of the pathophysiology and cause of progressive mandibular condylar resorption

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Review Section

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Analysis of Tumor Immunosuppressive Mechanisms in the Oral Cancer Invasive Microenvironment.Principal Investigator

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Association analysis of microtubules and the mechanism of highly invasive acquisition in oral cancer

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Evaluation of perioperative obstructive sleep apnea in patient with dentofacial deformity

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Explication of mechanisms on invasion and metastasis, and prevention of invasion and metastasis of oral squamous cell carcinoma

Principal Investigator

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Anti-inflammatory effect of MMP-3 on tissue regeneration in dental pulpitis.Principal Investigator

Principal Investigator

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Research Institution

The role of extracellular matrix degradation enzymes, MMP and ADAM in tumor micro environment (stem cell niche)Principal Investigator

Principal Investigator

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Research Institution

癌幹細胞微小環境(ニッチ)におけるMMPおよびADAMの役割検討Principal Investigator

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[Book] メタロプロテアーゼ関節リウマチ(寛解を目指す治療の新時代)第2版2010

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[Book] 炎症メディエーターメタロプロテアーゼ2010

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Publisher

Data Source

[Journal Article] Metalloelastase?12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selectively high efficacy of Eribulin against high-grade invasive recurrent and /or metastatic squamous cell carcinoma of the head and neck.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinicopathological Significace of the ET Axis in Human Oral Squamous Cell Carcinoma.2019

Author(s)

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DOI

Data Source

[Journal Article] Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage2018

Author(s)

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DOI

NAKAMURA HIROYUKI 中村博幸

NAKAMURA Hiroyuki 中村博幸