Asano Satoshi 浅野智志

… Alternative Names

ASANO Satoshi 浅野智志

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Researcher Number	30570535
Affiliation (Current)	2025: 広島大学, 医系科学研究科(歯), 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 広島大学, 医系科学研究科(歯), 助教 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 助教 2013 – 2016: 広島大学, 医歯薬保健学研究院(歯), 助教 2015: 広島大学, 医歯薬保健学研究院, 助教 2015: 広島大学, 大学院医歯薬保健学研究院, 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Pathobiological dentistry/Dental radiology / Functional basic dentistry
Keywords	Principal Investigator 細胞増殖 / 細胞移動 / 乳癌 / 転移 / イノシトールリン脂質 / VIPR2 / 細胞遊走 / PI3K / PI3-kinase / 神経ペプチド受容体 … More / Cell proliferation / GPCR / Cyclin D / Cell cycle / 細胞接着 / 遊走 / 糸状仮足 / VPAC2 / アクチン / ERK / Gαi / PI3キナーゼ / Gαs / VIP / 癌 / 乳がん / 細胞周期 / AKT / アポトーシス / シスプラチン / ミオシンII / PI(4,5)P2 / OCRL1 / RhoA / 細胞質分裂 / 細胞分裂 / 乳腺癌細胞 / 乳癌細胞 / 血小板増殖因子 / シグナル伝達 / 創傷治癒 / 細胞骨格 … More Except Principal Investigator 浸潤・転移 / シグナル伝達 / イノシトールリン脂質結合性タンパク質 / 細胞周期 / 癌転移 / 癌細胞浸潤 / 乳がん細胞株 / 肺がん細胞株 / イノシトールリン脂質結合性タンパク質 / がん細胞浸潤・転移 / 細胞運動 / AKT / PI(3,4,5)P3 / PI3K / PRIP / リン脂質代謝 / 細胞増殖 / 細胞浸潤 / 癌 / ベージュ細胞 / 寒冷刺激 / 脂肪分化 / 褐色脂肪細胞 / 白色脂肪細胞 / 脂肪代謝 / エネルギー代謝 / 脱分化 / 分化 / 脂肪細胞 Less

癌転移を制御するVIPR2受容体多量体化の病態的意義に関する創薬基盤研究Principal Investigator
- Principal Investigator
  
  浅野智志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima University
Development of novel cancer metastasis suppressing agent focusing on cell adhesion controlingPrincipal Investigator
- Principal Investigator
  
  Asano Satoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima University
Antitumor drug development research focusing on the novel cancer cell regulation mechanism of PRIPPrincipal Investigator
- Principal Investigator
  
  Asano Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Study on PRIP roles in cancer cell proliferation and migration
- Principal Investigator
  
  Kanematsu Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hiroshima University
Studied on the mechanisms of cancer metastasis and proliferation regulated by a new moleculePrincipal Investigator
- Principal Investigator
  
  Asano Satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.
- Principal Investigator
  
  Kanematsu Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
The study of blood clotting and venous repair regulated by a novel proteinPrincipal Investigator
- Principal Investigator
  
  ASANO Satoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

[Journal Article] Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells2024
- Author(s)
  Asano Satoshi、Ono Ami、Baba Kaede、Uehara Teru、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Yanamoto Souichi、Tanimoto Kotaro、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 3 Pages: 139-147
- DOI
  10.1016/j.jphs.2024.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06162, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628
[Journal Article] A new method for assessing depressive-like behaviors in female mice2023
- Author(s)
  吾郷由希夫, 浅野智志
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 1 Pages: 35-38
- DOI
  10.1254/fpj.22101
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PROJECT-23K09138
[Journal Article] Roles of the monoaminergic system in the antidepressant effects of ketamine and its metabolites2023
- Author(s)
  Ago Y, Yokoyama R, Asano S, Hashimoto H
- Journal Title
  
  Neuropharmacology
  
  Volume: 223 Pages: 109313-109313
- DOI
  10.1016/j.neuropharm.2022.109313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-22KJ2161, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H00492
[Journal Article] Development of the vasoactive intestinal peptide receptor 2 (VIPR2) antagonist peptide for the treatment of schizophrenia2023
- Author(s)
  Ago Yukio、Asano Satoshi、Sakamoto Kotaro
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 3 Pages: 242-245
- DOI
  10.1254/fpj.22146
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2023-05-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H03392
[Journal Article] Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway2023
- Author(s)
  Asano Satoshi、Ono Ami、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Tanimoto Kotaro、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Peptides
  
  Volume: 161 Pages: 170940-170940
- DOI
  10.1016/j.peptides.2023.170940
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-19K07121, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-23K06162, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H00492
[Journal Article] Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation2022
- Author(s)
  Imado E, Sun S, Abawa AR, Tahara T, Kochi T, Huynh TNB, Asano S, Hasebe S, Nakamura Y, Hisaoka-Nakashima K, Kotake Y, Irifune M, Tsuga K, Takuma K, Morioka N, Kiguchi N, Ago Y.
- Journal Title
  
  Neurochemistry International
  
  Volume: 160 Pages: 105415-105415
- DOI
  10.1016/j.neuint.2022.105415
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-21K10139, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H04342, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714
[Journal Article] Imipramine prevents Porphyromonas gingivalis lipopolysaccharide-induced microglial neurotoxicity2022
- Author(s)
  Yamawaki Yosuke、So Hiroki、Oue Kana、Asano Satoshi、Furusho Hisako、Miyauchi Mutsumi、Tanimoto Kotaro、Kanematsu Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 634 Pages: 92-99
- DOI
  10.1016/j.bbrc.2022.09.109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-21K11588, KAKENHI-PROJECT-20K09905
[Journal Article] Phospholipase C-related catalytically inactive protein enhances cisplatin-induced apoptotic cell death2022
- Author(s)
  Asano Satoshi、Maetani Yuka、Ago Yukio、Kanematsu Takashi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 933 Pages: 175273-175273
- DOI
  10.1016/j.ejphar.2022.175273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905
[Journal Article] AlphaFold version 2.0 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys25-Cys192) formation of functional significance for VIPR22022
- Author(s)
  Sakamoto K, Asano S, Ago Y, Hirokawa T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 636 Pages: 10-16
- DOI
  10.1016/j.bbrc.2022.10.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714
[Journal Article] Vasoactive intestinal peptide?VIPR2 signaling regulates tumor cell migration2022
- Author(s)
  Asano Satoshi、Yamasaka Misa、Ozasa Kairi、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Hashimoto Hitoshi、Waschek James A.、Ago Yukio
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 852358-852358
- DOI
  10.3389/fonc.2022.852358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-19K07121, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-20H00492
[Journal Article] Generation of KS-133 as a novel bicyclic peptide with a potent and selective VIPR2 antagonist activity that counteracts cognitive decline in a mouse model of psychiatric disorders2021
- Author(s)
  Sakamoto K, Chen L, Miyaoka T, Yamada M, Masutani T, Ishimoto K, Hino N, Nakagawa S, Asano S, Ago Y
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 751587-751587
- DOI
  10.3389/fphar.2021.751587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-20K11578, KAKENHI-PROJECT-21K06560, KAKENHI-PROJECT-21K19714
[Journal Article] Expression of PRIP, a phosphatidylinositol 4,5-bisphosphate binding protein, attenuates PI3K/AKT signaling and suppresses tumor growth in a xenograft mouse model2021
- Author(s)
  Maetani Yuka、Asano Satoshi、Mizokami Akiko、Yamawaki Yosuke、Sano Tomomi、Hirata Masato、Irifune Masahiro、Kanematsu Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 552 Pages: 106-113
- DOI
  10.1016/j.bbrc.2021.03.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-20H03854, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-21K10139
[Journal Article] Probing the VIPR2 microduplication linkage to schizophrenia in animal and cellular models2021
- Author(s)
  Ago Y, Asano S, Hashimoto H, Waschek JA
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 15 Pages: 717490-717490
- DOI
  10.3389/fnins.2021.717490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905
[Journal Article] Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism2020
- Author(s)
  Takeuchi Shuto、Kawanai Takuya、Yamauchi Ryosuke、Chen Lu、Miyaoka Tatsunori、Yamada Mei、Asano Satoshi、Hayata-Takano Atsuko、Nakazawa Takanobu、Yano Koji、Horiguchi Naotaka、Nakagawa Shinsaku、Takuma Kazuhiro、Waschek James A.、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 14 Pages: 521-532
- DOI
  10.3389/fnins.2020.00521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-20K21464, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-20H03392, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-19K07121
[Journal Article] Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure2019
- Author(s)
  Sano Tomomi、Sanada Taiki、Sotomaru Yusuke、Shinjo Takanori、Iwashita Misaki、Yamashita Akiko、Fukuda Takao、Sanui Terukazu、Asano Tomoichiro、Kanematsu Takashi、Nishimura Fusanori
- Journal Title
  
  Nutrition & Metabolism
  
  Volume: 16 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12986-019-0372-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11986
[Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019
- Author(s)
  Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Neurochemistry International
  
  Volume: 131 Pages: 104563-104563
- DOI
  10.1016/j.neuint.2019.104563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019
- Author(s)
  Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M
- Journal Title
  
  J Oral Biosci
  
  Volume: 61(2) Issue: 2 Pages: 65-72
- DOI
  10.1016/j.job.2019.04.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K17254
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019
- Author(s)
  Takashi Kanematsu, Kana Ouea, Toshiya Okumura, Kae Haradaa, Yosuke Yamawaki, Satoshi Asano, Akiko Mizokami, Masahiro Irifune, and Masato Hirata
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503
[Journal Article] Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow2019
- Author(s)
  Asano, S., Ikura, Y., Nishimoto, M., Yamawaki, Y., Hamao, K., Kamijo, K., Hirata, M. and Kanematsu, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 12729-12729
- DOI
  10.1038/s41598-019-49156-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice2018
- Author(s)
  Yamawaki Y, Yoshioka N, Nozaki K, Ito H, Oda K, Harada K, Shirawachi S, Asano S, Aizawa H, Yamawaki S, Kanematsu T, Akagi H
- Journal Title
  
  Brain research
  
  Volume: 1;1680 Pages: 13-38
- DOI
  10.1016/j.brainres.2017.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16H07001, KAKENHI-PROJECT-17K11644
[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice display increased induction of uncoupling protein 1 in adipose tissues following chronic cold exposure.2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 印刷中 Issue: 2 Pages: 108-112
- DOI
  10.1016/j.job.2017.04.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice.2017
- Author(s)
  Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
- Journal Title
  
  Journal of Anesthesia
  
  Volume: in press Issue: 4 Pages: 531-538
- DOI
  10.1007/s00540-017-2350-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation.2017
- Author(s)
  Yamawaki Y, Oue K, Shirawachi S, Asano S, Harada K, Kanematsu T.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 53（1） Issue: 1 Pages: 18-24
- DOI
  10.1016/j.jdsr.2016.06.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254
[Journal Article] Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance.2017
- Author(s)
  Sano T et al.
- Journal Title
  
  Nutr Metab Cardiovasc Dis
  
  Volume: 27 Issue: 3 Pages: 249-259
- DOI
  10.1016/j.numecd.2016.11.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H07067, KAKENHI-PROJECT-26463136, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11551, KAKENHI-PROJECT-16K11503
[Journal Article] Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling2017
- Author(s)
  Asano Satoshi、Taniguchi Yuri、Yamawaki Yosuke、Gao Jing、Harada Kae、Takeuchi Hiroshi、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5408-5408
- DOI
  10.1038/s41598-017-05908-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11479, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-15K11039
[Journal Article] Phospholipase C-related catalytically inactive protein is a new modulator of thermogenesis promoted by β-adrenergic receptors in brown adipocytes2015
- Author(s)
  Kana Oue, Jun Zhang, Kae Harada-Hada, Satoshi Asano, Yosuke Yamawaki, Masaki Hayashiuchi, Hisako Furusho, Takashi Takata, Masahiro Irifune, Masato Hirata, Takashi Kanematsu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 8 Pages: 4185-96
- DOI
  10.1074/jbc.m115.705723
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20437
[Journal Article] Phospholipase C-Related Catalytically Inactive Protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase2014
- Author(s)
  T. Okumura, K. Harada, K. Oue, J. Zhang, S. Asano, M. Hayashiuchi, A. Mizokami, H. Tanaka, M. Irifune, N. Kamata, M. Hirata, and T. Kanematsu.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 6 Pages: e100559-e100559
- DOI
  10.1371/journal.pone.0100559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-24229009
[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion2014
- Author(s)
  Satoshi Asano, Tomomi Nemoto, Tomoya Kitayama, Kae Harada, Jun Zhang, Kana Harada, Isei Tanida, Masato Hirata, and Takashi, Kanematsu
- Journal Title
  
  Biological Open
  
  Volume: 3 Issue: 6 Pages: 463-474
- DOI
  10.1242/bio.20147591
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22113005, KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009
[Journal Article] Phospholipase C-related catalytically inactive protein participates in the autophagic elimination of Staphylococcus aureus infecting mouse embryonic fibroblasts.2014
- Author(s)
  Harada-Hada K, Harada K, Kato F, Hisatsune J, Tanida I, Ogawa M, Asano S, Sugai M, Hirata M, Kanematsu T.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 5 Pages: e98285-e98285
- DOI
  10.1371/journal.pone.0098285
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460533, KAKENHI-PROJECT-25860321, KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009
[Patent] 癌転移抑制用のVIPR2 アンタゴニストペプチド2023
- Inventor(s)
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Holder
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2023
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 血管作動性腸管ペプチド受容体2シグナルはERK経路を介した乳癌細胞増殖に関与している2023
- Author(s)
  浅野智志, 小野亜美, 坂元孝太郎, 早田敦子, 中澤敬信, 谷本幸太郎, 橋本均, 吾郷由希夫
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] バルプロ酸の胎内曝露は中枢性感作と痛覚感受性の増大を引き起こす2023
- Author(s)
  吾郷由希夫, 田原孟, 今戸瑛二, 歌大介, 田熊一敞, 久米利明, 古武弥一郎, 浅野智志
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 二環式ペプチドKS-133とクラスB GPCR:VIPR2の結合メカニズム解明と機能的S-S結合の発見2023
- Author(s)
  坂元孝太郎, 浅野智志, 吾郷由希夫, 広川貴次
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 神経ペプチド受容体VIPR2の二量体化の機能的意義2023
- Author(s)
  浅野智志, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Role of the VPAC2 receptor overactivation implicated in schizophrenia susceptibility2023
- Author(s)
  Ami Ono, Daichi Koan, Tatsunori Miyaoka, Satoshi Asano, Shinsaku Nakagawa, James A. Waschek, Kotaro Tanimoto, Yukio Ago
- Organizer
  第56回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 統合失調症の発症脆弱性の解明を目指した神経細胞特異的VIPR2過剰発現マウスモデルの開発2023
- Author(s)
  小野亜美, 古庵大地, 宮岡辰典, 浅野智志, 橋本均, 中川晋作, 谷本幸太郎, 吾郷由希夫
- Organizer
  第2回広島大学脳神経科学セミナー
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] VPAC2受容体を標的とした新規の中分子による統合失調症治療薬の創出2023
- Author(s)
  吾郷由希夫, 坂元孝太郎, 浅野智志
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 統合失調症の発症脆弱性の解明を目指した神経細胞特異的VIPR2過剰発現マウスモデルの開発2023
- Author(s)
  小野亜美, 浅野智志, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 抗てんかん薬バルプロ酸の胎生期曝露は中枢性感作に伴う持続的な痛覚過敏とアロディニアを引き起こす2023
- Author(s)
  田原孟, 今戸瑛二, 歌大介, 浅野智志, 田熊一敞, 久米利明, 古武弥一郎, 吾郷由希夫
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 神経ペプチド受容体VIPR2による乳癌細胞遊走・増殖の新たな制御機構2023
- Author(s)
  浅野智志, 坂元孝太郎, 吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 乳癌の増殖・転移における神経ペプチド受容体VIPR2二量体化の機能的意義2023
- Author(s)
  浅野智志, 小野亜美, 上原輝, 谷本幸太郎, 柳本惣市, 吾郷由希夫
- Organizer
  第40回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] マウス胎生期のバルプロ酸曝露は脊髄でのミクログリアの増殖とアロディニアを引き起こす2022
- Author(s)
  吾郷由希夫, 今戸瑛二, Samnang Sun, 中村庸輝, 中島一恵, 森岡徳光, 田熊一敞, 木口倫一, 浅野智志
- Organizer
  Neuro2022 (第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Neuron-specific overexpression of human VPAC2 receptors in mice causes cognitive dysfunction2022
- Author(s)
  Ami Ono, Daichi Koan, Satoshi Asano, Tatsunori Miyaoka, Lu Chen, Mei Yamada, Shinsaku Nakagawa, Atsuko Hayata-Takano, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 神経発達障害モデルマウスにおける機械的アロディニアの発症とミクログリアの関与2022
- Author(s)
  今戸瑛二, Samnang Sun, Abawa Abrar, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 木口倫一, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 神経ペプチドVIPはVPAC2受容体を介するPI3K経路の活性化により細胞遊走を引き起こす2022
- Author(s)
  小笹かいり, 浅野智志, 山坂美紗, 早田敦子, 中澤敬信, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 神経ペプチド受容体VIPR2のオリゴマー化とその機能的意義2022
- Author(s)
  浅野智志, 小笹かいり, 中澤敬信, Waschek James, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Possible role of histone deacetylase inhibition in tactile hypersensitivity in a mouse model of autism spectrum disorder2022
- Author(s)
  Samnang Sun, Eiji Imado, Tran Ngoc Bao Huynh, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Norikazu Kiguchi, Satoshi Asano, Yukio Ago
- Organizer
  第37回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] A potential role of neuropeptide receptor VIPR2 signaling in tumor cell migration2022
- Author(s)
  Satoshi Asano, Misa Yamasaka, Kairi Ozasa, James Waschek, Yukio Ago
- Organizer
  第55回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 鎮痛作用を示さない低用量μオピオイド受容体アゴニストは自閉スペクトラム症モデルマウスの社会性行動障害を改善する2022
- Author(s)
  吾郷由希夫, 内藤恵, 川瀬啓生, 樋口桃子, 山川英訓, 大波壮一郎, 小川公一, 中邨篤史, 河内貴弘, 今戸瑛二, 田原孟, 浅野智志, 古武弥一郎, 田熊一敞, 橋本均
- Organizer
  第44回日本生物学的精神医学会年会、第32回日本臨床精神神経薬理学会年会、第52回日本神経精神薬理学会年会、第6回日本精神薬学会総会・学術集会 4学会合同年会（BPCNPNPPP4学会合同年会)
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Abnormal pain sensitivity associated with spinal microglial activation in a prenatal valproic acid-induced mouse model of autism2022
- Author(s)
  Eiji Imado, Sun Samnang, Abrar Rizal Abawa, Satoshi Asano, Kazuhiro Tsuga, Masahiro Irifune, Yukio Ago
- Organizer
  第55回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 神経ペプチド受容体VIPR2はPI3K経路を介してがん細胞遊走を制御する2022
- Author(s)
  浅野智志, 吾郷由希夫
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] The VIP/VIPR2 pathway regulates breast cancer cell migration2022
- Author(s)
  Satoshi Asano, Misa Yamasaka, Kairi Ozasa, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] TRPV1アンタゴニストAMG517は胎生期バルプロ酸投与誘発の自閉症モデルマウスにおいて痛覚感受性の異常と社会性行動障害を改善する2022
- Author(s)
  田原孟, 今戸瑛二, 川瀬啓生, 樋口桃子, 山川英訓, 小川公一, 古武弥一郎, 田熊一敞, 橋本均, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] PLC様タンパク質PRIP1のPH domain内包リポソームはシスプラチン耐性乳ガン細胞のアポトーシス細胞死を促進する2022
- Author(s)
  浅野智志, 吾郷由希夫, 兼松隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 胎生期のヒストン脱アセチル化酵素阻害は脊髄ミクログリアの活性化と機械的アロディニアを引き起こす2022
- Author(s)
  今戸瑛二, Sun Samnang, Huynh Ngoc Bao Tran, 中村庸輝, 中島一恵, 森岡徳光, 木口倫一, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] イミダゾールジペプチドの中枢作用に関する検討2022
- Author(s)
  山口稜太, 山口拓海, 中川晋作, 浅野智志, 松浦圭介, 中川正則, 吾郷由希夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 胎生期バルプロ酸投与マウスは熱刺激およびカプサイシン誘発痛の増大と機械的アロディニアを示す2021
- Author(s)
  今戸瑛二,浅野智志,中村庸輝,中島一恵,森岡徳光,津賀一弘,入舩正浩,田熊一敞, 吾郷由希夫
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 神経ペプチドVIP-VPAC2受容体シグナルは、がん細胞遊走を制御する新規の分子機構である2021
- Author(s)
  浅野智志, 吾郷由希夫
- Organizer
  第 63 回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] VPAC2 受容体の制御する細胞遊走メカニズム2021
- Author(s)
  山坂美紗, 浅野智志, 早田敦子, 中澤敬信, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  日本薬学会第 141 年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] A potent and highly selective VPAC2 receptor antagonist peptide KS-133 counteracts cognitive impairment in a mouse model relevant to schizophrenia2021
- Author(s)
  Yukio Ago, Lu Chen, Tatsunori Miyaoka, Mei Yamada, Teruaki Masutani, Kenji Ishimoto, Shinsaku Nakagawa, Satoshi Asano, Kotaro Sakamoto
- Organizer
  The 60th Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 新規選択的 VPAC2 受容体アンタゴニストペプチドの創製とその中枢薬理作用2021
- Author(s)
  山田めゐ, 陳露, 宮岡辰典, 桝谷晃明, 石本憲司, 樋野展正, 中川晋作, 浅野智志, 坂元孝太郎, 吾郷由希夫
- Organizer
  第 140 回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Overexpression of VIPR2 in neurons causes defects in dendritic growth and cognitive impairment2021
- Author(s)
  Tatsunori Miyaoka, Lu Chen, Mei Yamada, Daichi Koan, Satoshi Asano, Kenji Ishimoto, Shinsaku Nakagawa, Atsuko Hayata, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  The 7th Congress of the Asian College of Neuropsychopharmacology (AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] VPAC2受容体の制御する細胞遊走メカニズム2021
- Author(s)
  山坂美紗、浅野智志、早田敦子、中澤敬信、橋本均、Waschek James、吾郷由希夫
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Regulation of tumor cell migration by vasoactive intestinal peptide (VIP)－VPAC2 receptor signaling2021
- Author(s)
  Satoshi Asano, Misa Yamasaka, Kairi Ozasa, James A. Waschek, Yukio Ago
- Organizer
  The 6th Joint Scientific Meeting in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] ヒト VPAC2 受容体の過剰発現を細胞種特異的かつ時空間的に制御可能な新しいトランスジェニックマウスモデルの開発2021
- Author(s)
  宮岡辰典, 陳露, 山田めゐ, 古庵大地, 浅野智志, 石本憲司, 中川晋作, 早田敦子, 中澤敬信, 原田彰宏, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  第 43 回日本生物学的精神医学会・第 51 回日本神経精神薬理学会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] 脳神経細胞での VPAC2 受容体の過剰発現は認知機能障害を引き起こす2021
- Author(s)
  古庵大地,今戸瑛二,浅野智志,ChenLu,宮岡辰典,山田めゐ,石本憲司,中川晋作, 早田敦子, 中澤敬信, 原田彰宏, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  日本薬学会第 141 年会
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] Abnormal pain sensitivity in a prenatal valproic acid-induced mouse model of autism spectrum disorder2021
- Author(s)
  Eiji Imado, Sun Samnang, Abrar Rizal Abawa, Satoshi Asano, Kazuhiro Tsuga, Masahiro Irifune, Yukio Ago
- Organizer
  The 6th Joint Scientific Meeting in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905
[Presentation] PRIP regulates talin1 dimerization by binding to its dimerization domain, and controls fibronectin/integrin-mediated cell adhesion2019
- Author(s)
  Asano Satoshi, Kanematsu Takashi
- Organizer
  第61回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] 細胞接着に関与する新規タンパク質の発見と機能解析2019
- Author(s)
  浅野智志、兼松隆
- Organizer
  第14回細胞運動研究会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Regulation of cell adhesion by phospholipase C-related catalytically inactive protein (PRIP); PRIP directly promotes talin1 dimerization2019
- Author(s)
  浅野智志、兼松隆
- Organizer
  第52回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein modulates cytokinesis progression2019
- Author(s)
  Takashi Kanematsu, Satoshi Asano
- Organizer
  The 92th Annual Meeting of The Japanese Pharmacological Society
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] PRIP protects PI(4,5)P2 from its metabolic enzyme and contributes to completion of cytokinesis2018
- Author(s)
  Yasuka Ikura, Asano Satoshi, Kanematsu Takashi
- Organizer
  7th Hiroshima Conference
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein enhances cisplatin-induced apoptosis2018
- Author(s)
  Satoshi Asano, Yuka Maetani, Yasuka Ikura, Takashi Kanematsu
- Organizer
  8th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] PI(4,5)P2 metabolism regulator PRIP controls the metastatic potential in breast cancer cells2018
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  59th Chu-shikoku Branch Meeting of the Japanese Biochemical Society
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] スフィンゴリピッド代謝酵素に着目した細胞質分裂を制御する新規タンパク質の探索研究2018
- Author(s)
  浅野智志
- Organizer
  歯科基礎医学会平成30年度定時社員総会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] PRIP modulates AKT-GSK3β signaling and regulates cell cycle progression2018
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第51回広島大学歯学会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] A new molecular mechanism that regulates energy expenditure by regulating the function of white and brown adipocytes2018
- Author(s)
  Takashi Kanematsu, Kana Oue, Shuzo Sakata, Yosuke Yamawaki, Satoshi Asano
- Organizer
  The 60th Annual Meetings of Japanese Association for Oral Biology
- Invited
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] PRIP protects PI(4,5)P2 from its metabolic enzyme and contributes to completion of cytokinesis2018
- Author(s)
  Yasuka Ikura, Asano Satoshi, Kanematsu Takashi
- Organizer
  7th Hiroshima Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein regulates phosphatidylinositol metabolism and modulates cancer cell migration2018
- Author(s)
  Takashi Kanematsu, Satoshi Asano, Yosuke Yamawaki, Satoru Kusaka
- Organizer
  8th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] PRIPの過剰発現で乳癌細胞の腫瘍増殖は抑制される2018
- Author(s)
  前谷有香，浅野智志，兼松隆
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein protects PI(4,5)P2 from its metabolic enzyme and contributes to completion of cytokinesis2018
- Author(s)
  Yasuka Ikura, Satoshi Asano, Takashi Kanematsu
- Organizer
  7th Hiroshima Conference on Education and Science in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein, a phosphatidylinositol metabolism regulator, controls the metastatic potential in breast cancer cells2018
- Author(s)
  Takashi Kanematsu, Satoshi Asano
- Organizer
  The 8th Annual World Congress of Molecular & Cell Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] 新奇イノシトールリン脂質代謝調節タンパク質による乳がん細胞転移の制御機構の解明研究2018
- Author(s)
  浅野智志
- Organizer
  第60回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] PRIP modulates AKT-GSK3β signaling and regulates cell cycle progression2018
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  The 51th Annual Meeting of the Hiroshima University Dental Society
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] PI(4,5)P2 metabolism regulator PRIP controls the metastatic potential in breast cancer cells2018
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第59回日本生化学会中国・四国支部例会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein enhances cisplatin-induced apoptosis2018
- Author(s)
  Satoshi Asano, Yuka Maetani, Yasuka Ikura, Takashi Kanematsu
- Organizer
  8th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] 白色・褐色脂肪細胞の機能を制御しエネルギー代謝を調節する新しい分子基盤2018
- Author(s)
  兼松隆，大植香菜，坂田修三，山脇洋輔，浅野智志
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein regulates phosphatidylinositol metabolism and modulates cancer cell migration2018
- Author(s)
  Takashi Kanematsu, Satoshi Asano, Yosuke Yamawaki, Satoru Kusaka
- Organizer
  8th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Expression of PRIP in breast cancer cells downregulates tumor growth2018
- Author(s)
  Yuka Maetani, Satoshi Asano, Takashi Kanematsu
- Organizer
  The 60th Annual Meetings of Japanese Association for Oral Biology
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein regulates fat metabolism and energy expenditure2018
- Author(s)
  Takashi Kanematsu, Kana Oue, Yosuke Yamawaki, Satoshi Asano
- Organizer
  Obesity-2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein regulates fat metabolism and energy expenditure2018
- Author(s)
  Takashi Kanematsu, Kana Oue, Yosuke Yamawaki, Satoshi Asano
- Organizer
  7th European Congress on Obesity and Eating Disorder, New Emerging Drifts and Tactic to Challenge Obesity and Eating Disorder
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Phospholipase C-related catalytically inactive protein, a phosphatidylinositol metabolism regulator, controls the metastatic potential in breast cancer cells2018
- Author(s)
  Takashi Kanematsu, Satoshi Asano
- Organizer
  The 8th Annual World Congress of Molecular & Cell Biology
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Regulation of cytokinesis by phospholipase C-related catalytically inactive protein, as a sequestrant of PI(4,5)P2 in the cleavage furrow2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] The mechanism of phospholipase C-related catalytically inactive protein (PRIP)-mediated energy metabolism by β-adrenergic stimulation in brown adipocytes2017
- Author(s)
  大植香菜，山脇洋輔，浅野智志，入舩正浩，兼松隆
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Over expression of PRIP in MCF-7 cells, a breast cancer cell line, enhances cisplatin induced apoptosis2017
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第50回広島大学歯学会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  浅野智志、兼松隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  Asano S, Kanematsu T
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Over expression of PRIP in MCF-7 cells, a breast cancer cell line, enhances cisplatin induced apoptosis2017
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第50回広島大学歯学会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Regulation of cytokinesis by phospholipase C-related catalytically inactive protein, as a sequestrant of PI(4,5)P2 in the cleavage furrow2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] PRIP発現は癌細胞転移を抑制する2017
- Author(s)
  浅野智志、兼松隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Tumor cell migration is regulated by PRIP-mediated phosphatidylinositol turnover2016
- Author(s)
  浅野智志、兼松隆
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Suppression of PI3K-dependent breast cancer cell migration by PRIP2016
- Author(s)
  浅野智志、兼松隆
- Organizer
  GAP (Global Academic Program) related meeting
- Place of Presentation
  広島大学（広島県・広島市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Suppression of PI3K-dependent breast cancer cell migration by PRIP2016
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  GAP (Global Academic Program) related meeting
- Place of Presentation
  Hiroshima
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Suppression of breast cancer cell migration by PRIP, an upstream regulator of phosphoinositide 3-kinase signaling pathway2015
- Author(s)
  浅野智志、兼松隆
- Organizer
  第48回広島大学歯学会総会
- Place of Presentation
  広島大学（広島県・広島市）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] PRIP分子による細胞移動の調節PRIPは細胞膜におけるPI(3,4,5)P3合成を調節している2015
- Author(s)
  浅野智志、兼松隆
- Organizer
  第56回日本生化学会中国・四国支部例会
- Place of Presentation
  島根大学（島根県・松江市）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Regulation of second phase of insulin secretion by phospholipase C-related catalytically inactive protein2013
- Author(s)
  浅野智志
- Organizer
  46th meeting of the Hiroshima University Dental Society
- Place of Presentation
  広島大学
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Phospholipase C-related catalytically inactive protein modulates insulin secretory vesicle movement2013
- Author(s)
  浅野智志
- Organizer
  第５回広島カンファレンス
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of insulin secretion by phospholipase C-related catalytically inactive protein2013
- Author(s)
  浅野智志
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of cell migration by phospholipase C-related catalytically inactive protein
- Author(s)
  S. Asano, and T. Kanematsu.
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of cell migration by PRIP: PRIP protects PI(4,5)P2 and decreases PDGF-induced PI(3,4,5)P3 synthesis in the plasma membrane
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25861756

1. Kanematsu Takashi (10264053)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. YAMAWAKI YOSUKE (90584061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. HARADA KAE (60432663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 吾郷由希夫 (50403027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
5. OUE KANA

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. Maetani Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. IRIFUNE Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NAKAZAWA Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. NAKATSU Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐野朋美

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 伊藤日加瑠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 田熊一浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 根本知己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高野敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 橋本均

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 高靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 久恒順三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 菅井基行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 平田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Asano Satoshi 浅野 智志

ASANO Satoshi 浅野 智志

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癌転移を制御するVIPR2受容体多量体化の病態的意義に関する創薬基盤研究Principal Investigator

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Development of novel cancer metastasis suppressing agent focusing on cell adhesion controlingPrincipal Investigator

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Antitumor drug development research focusing on the novel cancer cell regulation mechanism of PRIPPrincipal Investigator

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Study on PRIP roles in cancer cell proliferation and migration

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Studied on the mechanisms of cancer metastasis and proliferation regulated by a new moleculePrincipal Investigator

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Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.

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The study of blood clotting and venous repair regulated by a novel proteinPrincipal Investigator

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[Journal Article] Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells2024

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[Journal Article] A new method for assessing depressive-like behaviors in female mice2023

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[Journal Article] Roles of the monoaminergic system in the antidepressant effects of ketamine and its metabolites2023

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[Journal Article] Development of the vasoactive intestinal peptide receptor 2 (VIPR2) antagonist peptide for the treatment of schizophrenia2023

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[Journal Article] Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway2023

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[Journal Article] Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation2022

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Asano Satoshi 浅野智志

ASANO Satoshi 浅野智志