AGO Yukio 吾郷由希夫

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Ago Yukio 吾郷由希夫

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Researcher Number	50403027
Other IDs
Affiliation (Current)	2026: 広島大学, 医系科学研究科(歯), 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 広島大学, 医系科学研究科(歯), 教授 2018: 大阪大学, 薬学研究科, 准教授 2016 – 2017: 大阪大学, 薬学研究科, 助教 2011 – 2015: 大阪大学, 薬学研究科(研究院), 助教 2013: 大阪大学, 薬学研究科, 大阪大学 … More 2012: 大阪大学, 大学院・薬学研究科, 助教 2007 – 2011: Osaka University, 薬学研究科, 助教 2010: Osaka University, 大学院・薬学研究科, 助教 2008: 大阪大学, 大学院・薬学研究科, 助教 2006: 大阪大学, 薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Applied pharmacology / Basic Section 58080:Gerontological nursing and community health nursing-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 57030:Conservative dentistry-related / Basic Section 57020:Oral pathobiological science-related … More / Basic Section 52030:Psychiatry-related / Basic Section 48030:Pharmacology-related / Basic Section 47060:Clinical pharmacy-related / Pharmacology in pharmacy / General pharmacology / Biological pharmacy Less
Keywords	Principal Investigator 統合失調症 / 大脳皮質前頭前野 / ドラッグデリバリーシステム / 遺伝子改変マウス / iPS細胞 / VIPR2 / コピー数変異 / 雌選択性試験 / 抗うつ薬 / 精神疾患 … More / ドパミン / 環境因子 / 認知機能障害 / うつ病 / 長期隔離飼育マウス / 神経ペプチド / 神経細胞 / 樹状突起スパイン / マウス / 運動 / 環境強化 / ペプチド / アンタゴニスト / 前頭葉 / アンヘドニア / 腹側被蓋野 / c-Fos / 細胞内カルシウム / PC12細胞 / SH-SY5Y細胞 / 5-HT1A 受容体 / σ1受容体 / 抗不安作用 / 抗うつ作用 / 相互作用 / GABAA受容体 / 5-HT1A受容体 / シグマ1受容体 / モノアミン / グルタミン酸神経 / 覚せい剤 / 個体間相互作用 / エンカウンター刺激 / グルタミン酸神経系 / 環境ストレス / 代謝型グルタミン酸2/3受容体 / 海馬 / グリア細胞 / グルココルチコイド / 環境要因 / 代謝型グルタミン酸2/3受容体 (mGlu2/3受容体) / プレパルスインヒビション障害 / アセチルコリン / 神経栄養因子 / ムスカリン受容体 / プレパルスインヒビション(PPI) / PACAP / アセチルコリン(ACh) / 精神疾患病態モデル / マイクロダイアリシス法 / プレパルスインヒビション / ミトコンドリア / 併用療法 / 抗精神病薬 / SSRI … More Except Principal Investigator 精神疾患 / 薬理学 / ペントバルビタール / ストレス / 環境要因 / SEA0400 / アストロサイト / 脳神経疾患 / うつ病 / 自律神経反応評価 / 健忘 / 意識消失 / 筋電位 / 脳波 / バルビツール酸系全身麻酔薬 / 不動化 / 抗侵害効果 / 握力試験 / 正向反射の障害・消失 / 全身麻酔作用評価 / 脳機能改善 / 認知症予防 / 認知機能バイオマーカー / 介護予防 / 認知機能低下予防 / アルツハイマー型認知症 / 認知機能 / 咀嚼運動 / 唾液中irisin / 自閉スペクトラム症 / 遺伝要因 / 発達神経毒性物質 / ミクログリア / 神経炎症 / 認知症 / 認知機能障害 / 歯周病 / 肥満 / 神経ペプチド受容体 / 乳癌 / 転移 / Cell proliferation / Cyclin D / Cell cycle / VPAC2 / VIPR2 / VIP / 細胞遊走 / 細胞増殖 / 乳がん / 二量体 / GPCR / βヒドロキシ酪酸 / NLRP3 / 炎症 / 光遺伝学 / 視床 / 麻酔・鎮静深度調節法の開発 / GBR-12909 / オプトジェネティクス / ドパミン受容体作動薬 / レセルピン / 麻酔覚醒 / DA取り込み阻害薬 / 脳波・筋電図測定 / マイクロダイアリシス法 / 線条体 / 側坐核 / ドパミン受容体リガンド / 鎮静深度調節 / 乳酸 / グリコーゲン / 培養アストロサイト / 不安・うつ様行動 / グルタミン酸受容体 / 恐怖記憶 / PTG / アストロサイト-ニューロン乳酸シャトル / 下垂体アデニル酸シクラーゼ活性化ポリペプチド / 神経アストロサイト機能連関 / 不安・うつ行動 / 社会的・心理的ストレス / 下垂体アデニル酸シクラーゼ活性化ペプチド / 背側海馬 / 嗅周皮質 / アデニル酸シクラーゼ活性化ペプチド / 情動障害 / PAC1R / 学習記憶 / ADCYAP / 下垂体アデニル酸シクラーぜ活性化ペプチド / 安全性 / 体内動態 / 安全科学 / 薬物動態 / アジュバント / 経鼻ワクチン / 感染症 / ワクチン / Resident-intruder試験 / Resident-Intruder試験 / 覚せい剤精神病 / 難治性うつ病 / 自閉症 / 樹状突起スパイン / 豊かな環境飼育 / 社会的相互作用試験 / エンカウンター試験 / 発達障害 / ドパミン / Nitric oxide (NO) / Na+/Ca2+交換系(NCX) / 精神機能 / 細胞障害 / 一酸化窒素（NO） / 一酸化窒素 / Na+/Ca2+交換系 / エピジェネティクス / バルプロ酸 / 海馬 / ヒストン / PACAP遺伝子欠損マウス / エピジェネテクス / nitric oxide (NO) / ドパミン神経 / Ca^<2+> exchanger (NCX) / microdialysis / nitric oxide(NO) / ドパモン神経 / Parkinson / Ca^<2+>exchanger(NCX) / Ca^<2+> / SH-SY5Y細胞 / Na^+/Ca^<2+>交感系(NCX) / パーキンソン病 / MPTP / 一酸化窒素(NO) / Ca^<2+>交換系(NCX) / Na^+ / SNPs(一塩基多型) / 統合失調症 / 一塩基多型(SNP) / 分子遺伝学 / early growth response / セロトニン神経 / ADHD / 疾患モデル / 遺伝子改変マウス / 精神疾患・障害 / 神経ペプチドPACAP / 臨床遺伝学 Less

Clinical development of a novel, patient-optimized, inflammation-targeted antidepressant
- Principal Investigator
  
  岩田正明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Tottori University
Elucidation of the pathological mechanism of treatment-refractory schizophrenia and drug discovery research focusing on abnormalities in peptide signaling during brain developmentPrincipal Investigator
- Principal Investigator
  
  吾郷由希夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hiroshima University
唾液中イリシンを指標とした咀嚼運動による脳機能改善機序と認知機能評価に関する研究
- Principal Investigator
  
  讃井真理
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Hiroshima University
The development of novel general anesthetics using effectiveness assessment of drug candidates by EEG and EMG
- Principal Investigator
  
  入舩正浩
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
癌転移を制御するVIPR2受容体多量体化の病態的意義に関する創薬基盤研究
- Principal Investigator
  
  浅野智志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima University
Elucidating the mechanisms of interaction between obesity pathology and periodontal infection on cognitive function
- Principal Investigator
  
  大植香菜
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
発達神経毒性物質と遺伝要因の両者による自閉スペクトラム症発症に関する基礎研究
- Principal Investigator
  
  古武弥一郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hiroshima University
Development of a control method for depth of anesthesia and/or sedation applied to a selective dopamine receptor subtype ligand.
- Principal Investigator
  
  Irifune Masahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Identification of novel factors mediating the effects of environmental enrichment in the absence of voluntary exercise on psychiatric disordersPrincipal Investigator
- Principal Investigator
  
  Ago Yukio
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Hiroshima University
Development of the integrated therapeutic strategy aiming toward drug discovery and pharmacotherapy for treatment-resistant schizophreniaPrincipal Investigator
- Principal Investigator
  
  Ago Yukio
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Hiroshima University
Development of effective and safe nasal vaccines based on the control of antigen kinetics
- Principal Investigator
  
  Yoshioka Yasuo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Osaka University
Pathophysiological significance of neuron-astrocyte implication of PACAP on stress-induced emotional disorder
- Principal Investigator
  
  Miyata Atsuro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kagoshima University
Drug discovery research targeting the novel regulation of prefrontal dopaminergic system by the functional interaction between the sigma1 and serotonin1A receptorsPrincipal Investigator
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Neurochemical study for cognitive behavioral therapy in mouse models of neuropsychiatric and neurodevelopmental disorders
- Principal Investigator
  
  Takuma Kazuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Drug discovery research targeting brain neurochemical signals responsible for induction of abnormal behaviors in mouse models of psychiatric disordersPrincipal Investigator
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
Study on pathophysiological roles of brain NO-NCX signal
- Principal Investigator
  
  MATSUDA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University
Neuropharmacological study on drug development targeting forbrain metabotropic glutamate 2/3 receptorsPrincipal Investigator
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University
創薬を目指した環境要因誘発精神疾患動物でのエピジェネティクス研究
- Principal Investigator
  
  松田敏夫
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
Research for the cholinergic basis of cognitive dysfunction in schizophreniaPrincipal Investigator
- Principal Investigator
  
  AGO Yukio
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University
Basic studies on drug development targeting for brain NCX
- Principal Investigator
  
  MATSUDA Toshio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University
Molecular genetic study on the pathophysiology of psychiatric disorders based on the role of PACAP
- Principal Investigator
  
  SHINTANI Norihito, HASHIMOTO Hitoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
統合失調症治療におけるSSRI併用療法の神経科学的基盤に関する研究Principal Investigator
- Principal Investigator
  
  吾郷由希夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Osaka University

[Journal Article] Dimerisation of the VIP receptor VIPR2 is essential to its binding VIP and Gα<sub>i</sub> proteins, and to its functions in breast cancer cells2025
- Author(s)
  Asano Satoshi、Ozasa Kairi、Uehara Teru、Yokoyama Rei、Nakazawa Takanobu、Yanamoto Souichi、Ago Yukio
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: － Issue: 15 Pages: 3612-3627
- DOI
  10.1111/bph.70039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02182, KAKENHI-PROJECT-24K02185, KAKENHI-PROJECT-23K09138
[Journal Article] Cyclic Peptides KS-133 and KS-487 Multifunctionalized Nanoparticles Enable Efficient Brain Targeting for Treating Schizophrenia2024
- Author(s)
  Sakamoto Kotaro、Iwata Seigo、Jin Zihao、Chen Lu、Miyaoka Tatsunori、Yamada Mei、Katahira Kaiga、Yokoyama Rei、Ono Ami、Asano Satoshi、Tanimoto Kotaro、Ishimura Rika、Nakagawa Shinsaku、Hirokawa Takatsugu、Ago Yukio、Miyako Eijiro
- Journal Title
  
  JACS Au
  
  Volume: 4 Issue: 8 Pages: 2811-2817
- DOI
  10.1021/jacsau.4c00311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H00551, KAKENHI-PROJECT-22K18440, KAKENHI-PROJECT-24K02185, KAKENHI-PROJECT-23K09138
[Journal Article] Brain region-specific neural activation by low-dose opioid promotes social behavior2024
- Author(s)
  Ohnami Soichiro、Naito Megumi、Kawase Haruki、Higuchi Momoko、Hasebe Shigeru、Takasu Keiko、Kanemaru Ryo、Azuma Yuki、Yokoyama Rei、Kochi Takahiro、Imado Eiji、Tahara Takeru、Kotake Yaichiro、Asano Satoshi、Oishi Naoya、Takuma Kazuhiro、Hashimoto Hitoshi、Ogawa Koichi、Nakamura Atsushi、Yamakawa Hidekuni、Ago Yukio
- Journal Title
  
  JCI Insight
  
  Volume: 9 Issue: 23 Pages: 1-14
- DOI
  10.1172/jci.insight.182060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H00450, KAKENHI-PROJECT-24K02185, KAKENHI-PROJECT-22K02474, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-24K09831, KAKENHI-PROJECT-24K10808, KAKENHI-PROJECT-23K19455, KAKENHI-PROJECT-24K23296
[Journal Article] Oral administration of <i>Porphyromonas gingivalis</i> to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain2024
- Author(s)
  Oue Kana、Yamawaki Yosuke、Ouhara Kazuhisa、Imado Eiji、Tamura Tetsuya、Doi Mitsuru、Shimizu Yoshitaka、Yoshida Mitsuhiro、Mizuno Noriyoshi、Morioka Norimitsu、Kanematsu Takashi、Irifune Masahiro、Ago Yukio
- Journal Title
  
  Journal of Oral Microbiology
  
  Volume: 16 Issue: 1 Pages: 2419155-2419155
- DOI
  10.1080/20002297.2024.2419155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11588, KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-20K18669, KAKENHI-PROJECT-24K02185, KAKENHI-PROJECT-23K09183, KAKENHI-PROJECT-24K13089, KAKENHI-PROJECT-23K19455
[Journal Article] A Behavioral and Electroencephalographic Study of Anesthetic State Induced by MK-801 Combined with Haloperidol, Ketamine and Riluzole in Mice2024
- Author(s)
  Kikuchi Yuka、Irifune Masahiro、Yoshinaka Taiga、Oue Kana、Takahashi Tamayo、Oda Aya、Kamio Hisanobu、Imamura Serika、Sasaki Utaka、Imado Eiji、Ago Yukio、Okada Yoshiyuki
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: Online ahead of print Issue: 5 Pages: 1-11
- DOI
  10.1213/ane.0000000000006900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10139, KAKENHI-PROJECT-24K13089
[Journal Article] Long-lasting anti-despair and anti-anhedonia effects of (S)-norketamine in social isolation-reared mice2024
- Author(s)
  Yokoyama Rei、Higuchi Momoko、Tanabe Wataru、Tsukada Shinji、Igarashi Hisato、Seiriki Kaoru、Nakazawa Takanobu、Kasai Atsushi、Ago Yukio、Hashimoto Hitoshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 2 Pages: 72-76
- DOI
  10.1016/j.jphs.2023.12.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19378, KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-22KJ2161, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628
[Journal Article] (R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice2024
- Author(s)
  Yokoyama Rei、Ago Yukio、Igarashi Hisato、Higuchi Momoko、Tanuma Masato、Shimazaki Yuto、Kawai Takafumi、Seiriki Kaoru、Hayashida Misuzu、Yamaguchi Shun、Tanaka Hirokazu、Nakazawa Takanobu、Okamura Yasushi、Hashimoto Kenji、Kasai Atsushi、Hashimoto Hitoshi
- Journal Title
  
  Molecular Psychiatry
  
  Volume: - Issue: 5 Pages: 1-11
- DOI
  10.1038/s41380-024-02419-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19350, KAKENHI-PROJECT-20K07274, KAKENHI-PROJECT-21K11200, KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-22KJ2161, KAKENHI-PROJECT-20KK0376, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-23K24066, KAKENHI-PLANNED-22H05082, KAKENHI-PROJECT-22K19378, KAKENHI-PROJECT-23K06334
[Journal Article] Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells2024
- Author(s)
  Asano Satoshi、Ono Ami、Baba Kaede、Uehara Teru、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Yanamoto Souichi、Tanimoto Kotaro、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 3 Pages: 139-147
- DOI
  10.1016/j.jphs.2024.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06162, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628
[Journal Article] N-methyl-d-aspartate receptors and glycinergic transmission, respectively, mediate muscle relaxation and immobility of pentobarbital in mice2023
- Author(s)
  Mukai Akari、Irifune Masahiro、Shimizu Yoshitaka、Doi Mitsuru、Kikuchi Yuka、Katayama Sotaro、Oue Kana、Yoshida Mitsuhiro、Ago Yukio、Okada Yoshiyuki、Morioka Norimitsu、Nakata Yoshihiro、Sakai Norio
- Journal Title
  
  Neuroscience Letters
  
  Volume: 802 Pages: 137175-137175
- DOI
  10.1016/j.neulet.2023.137175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06361, KAKENHI-PROJECT-21K10139
[Journal Article] Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy2023
- Author(s)
  Ishimoto K, Konishi Y, Otani S, Maeda S, Ago Y, Hino N, Suzuki M, Nakagawa S.
- Journal Title
  
  J Nat Med.
  
  Volume: in press Issue: 3 Pages: 604-609
- DOI
  10.1007/s11418-023-01686-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11578, KAKENHI-PROJECT-21K06560, KAKENHI-PROJECT-20H03392
[Journal Article] The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody2023
- Author(s)
  Sakamoto K, Kittikulsuth W, Miyako E, Steeve A, Ishimura R, Nakagawa S, Ago Y, Nishiyama A
- Journal Title
  
  PLoS One
  
  Volume: 18 Issue: 7 Pages: e0286651-e0286651
- DOI
  10.1371/journal.pone.0286651
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Journal Article] A new method for assessing depressive-like behaviors in female mice2023
- Author(s)
  吾郷由希夫, 浅野智志
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 1 Pages: 35-38
- DOI
  10.1254/fpj.22101
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PROJECT-23K09138
[Journal Article] Overexpression of VIPR2 in mice results in microencephaly with paradoxical increased white matter volume2023
- Author(s)
  Ago Y, Van C, Condro MC, Hrncir H, Diep AL, Rajbhandari AK, Fanselow MS, Hashimoto H, MacKenzie-Graham AJ, Waschek JA
- Journal Title
  
  Experimental Neurology
  
  Volume: 362 Pages: 114339-114339
- DOI
  10.1016/j.expneurol.2023.114339
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H00492
[Journal Article] Roles of the monoaminergic system in the antidepressant effects of ketamine and its metabolites2023
- Author(s)
  Ago Y, Yokoyama R, Asano S, Hashimoto H
- Journal Title
  
  Neuropharmacology
  
  Volume: 223 Pages: 109313-109313
- DOI
  10.1016/j.neuropharm.2022.109313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-22KJ2161, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H00492
[Journal Article] Development of the vasoactive intestinal peptide receptor 2 (VIPR2) antagonist peptide for the treatment of schizophrenia2023
- Author(s)
  Ago Yukio、Asano Satoshi、Sakamoto Kotaro
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 158 Issue: 3 Pages: 242-245
- DOI
  10.1254/fpj.22146
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2023-05-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H03392
[Journal Article] Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway2023
- Author(s)
  Asano Satoshi、Ono Ami、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Tanimoto Kotaro、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Peptides
  
  Volume: 161 Pages: 170940-170940
- DOI
  10.1016/j.peptides.2023.170940
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-19K07121, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-23K06162, KAKENHI-PROJECT-23K09138, KAKENHI-PROJECT-20H00492
[Journal Article] Phospholipase C-related catalytically inactive protein enhances cisplatin-induced apoptotic cell death2022
- Author(s)
  Asano Satoshi、Maetani Yuka、Ago Yukio、Kanematsu Takashi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 933 Pages: 175273-175273
- DOI
  10.1016/j.ejphar.2022.175273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905
[Journal Article] Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion2022
- Author(s)
  Ishimoto Kenji、Shimada Yukiko、Ohno Akane、Otani Shuichi、Ago Yukio、Maeda Soya、Lin Bangzhong、Nunomura Kazuto、Hino Nobumasa、Suzuki Masayuki、Nakagawa Shinsaku
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 9 Pages: 850103-850103
- DOI
  10.3389/fnut.2022.850103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06560, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K11578
[Journal Article] Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation2022
- Author(s)
  Imado E, Sun S, Abawa AR, Tahara T, Kochi T, Huynh TNB, Asano S, Hasebe S, Nakamura Y, Hisaoka-Nakashima K, Kotake Y, Irifune M, Tsuga K, Takuma K, Morioka N, Kiguchi N, Ago Y.
- Journal Title
  
  Neurochemistry International
  
  Volume: 160 Pages: 105415-105415
- DOI
  10.1016/j.neuint.2022.105415
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-21K10139, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H04342, KAKENHI-PROJECT-20K09227, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714
[Journal Article] Vasoactive intestinal peptide?VIPR2 signaling regulates tumor cell migration2022
- Author(s)
  Asano Satoshi、Yamasaka Misa、Ozasa Kairi、Sakamoto Kotaro、Hayata-Takano Atsuko、Nakazawa Takanobu、Hashimoto Hitoshi、Waschek James A.、Ago Yukio
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 852358-852358
- DOI
  10.3389/fonc.2022.852358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-19K07121, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-20H00492
[Journal Article] AlphaFold version 2.0 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys25-Cys192) formation of functional significance for VIPR22022
- Author(s)
  Sakamoto K, Asano S, Ago Y, Hirokawa T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 636 Pages: 10-16
- DOI
  10.1016/j.bbrc.2022.10.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-21K19714
[Journal Article] Probing the VIPR2 microduplication linkage to schizophrenia in animal and cellular models2021
- Author(s)
  Ago Y, Asano S, Hashimoto H, Waschek JA
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 15 Pages: 717490-717490
- DOI
  10.3389/fnins.2021.717490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905
[Journal Article] Generation of KS-133 as a novel bicyclic peptide with a potent and selective VIPR2 antagonist activity that counteracts cognitive decline in a mouse model of psychiatric disorders2021
- Author(s)
  Sakamoto K, Chen L, Miyaoka T, Yamada M, Masutani T, Ishimoto K, Hino N, Nakagawa S, Asano S, Ago Y
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 751587-751587
- DOI
  10.3389/fphar.2021.751587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-20K11578, KAKENHI-PROJECT-21K06560, KAKENHI-PROJECT-21K19714
[Journal Article] PACAPシグナル系を介したストレスが誘発する精神疾患の発症機序の解明と治療薬の開発2021
- Author(s)
  早田敦子, 吾郷由希夫, 橋本均
- Journal Title
  
  細胞
  
  Volume: 53 Pages: 60-63
- NAID
  40022470686
- Data Source
  KAKENHI-PROJECT-20H03392
[Journal Article] Safety and efficacy of an anti-claudin-5 monoclonal antibody to increase blood-brain barrier permeability for drug delivery to the brain in a non-human primate2021
- Author(s)
  Tachibana K, Hashimoto Y, Shirakura K, Okada Y, Hirayama R, Iwashita Y, Nishino I, Ago Y, Takeda H, Kuniyasu H, Kondoh M
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 336 Pages: 105-111
- DOI
  10.1016/j.jconrel.2021.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20K05709, KAKENHI-PROJECT-20K21659, KAKENHI-PROJECT-21H03354, KAKENHI-PROJECT-20H03382
[Journal Article] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia2021
- Author(s)
  Yamamoto Kana、Kuriu Toshihiko、Takuma Kazuhiro、Ono Fumihito、Matsumoto Naomichi、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 548-548
- DOI
  10.1038/s41398-021-01676-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-18H05416, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-21J15163, KAKENHI-PROJECT-20K07057, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-21K19335, KAKENHI-PROJECT-19H01047
[Journal Article] The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory2021
- Author(s)
  Kambe Y, Yamauchi Y, Thanh Nguyen T, Thi Nguyen T, Ago Y, Shintani N, Hashimoto H, Yoshitake S, Yoshitake T, Kehr J, Kawamura N, Katsuura G, Kurihara T, Miyata A
- Journal Title
  
  Pharmacol. Rep.
  
  Volume: 73 Issue: 4 Pages: 1109-1121
- DOI
  10.1007/s43440-021-00222-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03429, KAKENHI-PROJECT-20K07067
[Journal Article] PACAPシグナル系を介したストレスが誘発する精神疾患の発症機序の解明と治療薬の開発2020
- Author(s)
  早田敦子, 吾郷由希夫, 橋本均
- Journal Title
  
  Medical Science Digest
  
  Volume: 46 Pages: 54-57
- NAID
  40022470686
- Data Source
  KAKENHI-PROJECT-20H03392
[Journal Article] Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism2020
- Author(s)
  Takeuchi Shuto、Kawanai Takuya、Yamauchi Ryosuke、Chen Lu、Miyaoka Tatsunori、Yamada Mei、Asano Satoshi、Hayata-Takano Atsuko、Nakazawa Takanobu、Yano Koji、Horiguchi Naotaka、Nakagawa Shinsaku、Takuma Kazuhiro、Waschek James A.、Hashimoto Hitoshi、Ago Yukio
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 14 Pages: 521-532
- DOI
  10.3389/fnins.2020.00521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09905, KAKENHI-PROJECT-20K21464, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-20H03392, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-19K07121
[Journal Article] 精神神経機能障害における遺伝／環境因子の役割2020
- Author(s)
  吾郷由希夫
- Journal Title
  
  広島大学歯学雑誌
  
  Volume: 52 Pages: 55-61
- NAID
  40022485269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03392
[Journal Article] mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.2019
- Author(s)
  Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H.
- Journal Title
  
  Pharmacol Biochem Behav.
  
  Volume: 176 Pages: 1-5
- DOI
  10.1016/j.pbb.2018.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-18H02574
[Journal Article] Repeated social defeat stress impairs attentional set shifting irrespective of social avoidance and increases female preference associated with heightened anxiety2018
- Author(s)
  Higashida Shu、Nagai Hirotaka、Nakayama Kazuki、Shinohara Ryota、Taniguchi Masayuki、Nagai Midori、Hikida Takatoshi、Yawata Satoshi、Ago Yukio、Kitaoka Shiho、Narumiya Shuh、Furuyashiki Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10454-10454
- DOI
  10.1038/s41598-018-28803-1
- NAID
  120006501224
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08593, KAKENHI-PLANNED-16H06568, KAKENHI-PUBLICLY-17H05572, KAKENHI-PUBLICLY-17H06057, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-18H02542, KAKENHI-PROJECT-17J09360, KAKENHI-PROJECT-16K06993, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K14579, KAKENHI-PROJECT-17K19457
[Journal Article] うつ／不安症状に対するσ1受容体－セロトニン1A受容体の機能的相互作用による治療・創薬戦略.2018
- Author(s)
  吾郷由希夫
- Journal Title
  
  医薬品医療機器レギュラトリーサイエンス
  
  Volume: 49 Pages: 550-556
- Data Source
  KAKENHI-PROJECT-16K08268
[Journal Article] LY341495, an mGluR2/3 Antagonist, Regulates the Immunosuppressive Function of Myeloid-Derived Suppressor Cells and Inhibits Melanoma Tumor Growth2018
- Author(s)
  Morikawa N, Tachibana M, Ago Y, Goda H, Sakurai F, Mizuguchi H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 12 Pages: 1866-1869
- DOI
  10.1248/bpb.b18-00055
- NAID
  130007539555
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08268
[Journal Article] Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice2017
- Author(s)
  Hara Y, Ago Y, Taruta A, Hasebe S, Kawase H, Tanabe W, Tsukada S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 234(21) Issue: 21 Pages: 3217-3228
- DOI
  10.1007/s00213-017-4703-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice2017
- Author(s)
  Hasebe S, Ago Y, Watabe Y, Oka S, Hiramatsu N, Tanaka T, Umehara C, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 4 Pages: 314-327
- DOI
  10.1111/bph.13692
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-26293020
[Journal Article] Impaired extinction of cued fear memory and abnormal dendritic morphology of the prelimbic and infralimbic cortices in VPAC2 receptor (VIPR2)-deficient mice2017
- Author(s)
  Ago Y, Hayata-Takano A, Kawanai T, Yamauchi R, Takeuchi S, Cushman JD, Rajbhandari AK, Fanselow MS, Hashimoto H, Waschek JA
- Journal Title
  
  Neurobiology of Learning and Memory
  
  Volume: 145 Pages: 222-231
- DOI
  10.1016/j.nlm.2017.10.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-17H03989
[Journal Article] Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice2017
- Author(s)
  Yamaguchi H, Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Behav. Brain Res.
  
  Volume: 333 Pages: 67-73
- DOI
  10.1016/j.bbr.2017.06.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Psychopharmacology of combined activation of the serotonin1A and σ1 receptors2017
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 809 Pages: 172-177
- DOI
  10.1016/j.ejphar.2017.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126
[Journal Article] Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism2017
- Author(s)
  Hara Y, Ago Y, Higuchi M, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Hormones and Behavior
  
  Volume: 96 Pages: 130-136
- DOI
  10.1016/j.yhbeh.2017.09.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain.2017
- Author(s)
  Hara Y, Ago Y, Takano E, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T, Takuma K.
- Journal Title
  
  Molecular Autism
  
  Volume: 8 Issue: 1 Pages: 33-33
- DOI
  10.1186/s13229-017-0149-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-15H04645
[Journal Article] Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice2016
- Author(s)
  Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Int. J. Neuropsychopharmacol.
  
  Volume: 20 Pages: 410-420
- DOI
  10.1093/ijnp/pyw115
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-14J06155, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183, KAKENHI-PROJECT-16K08268
[Journal Article] Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism2016
- Author(s)
  Hara Y, Ago Y, Taruta A, Katashiba K, Hasebe S, Takano E, Onaka Y, Hashimoto H, Matsuda T, Takuma K
- Journal Title
  
  Autism Research
  
  Volume: - Issue: 9 Pages: 926-939
- DOI
  10.1002/aur.1596
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-13J05359, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K19183
[Journal Article] The novel method female encounter test2016
- Author(s)
  吾郷由希夫, 長谷部　茂, 橋本　均, 田熊一敞, 松田敏夫
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 4 Pages: 230-234
- DOI
  10.1254/fpj.147.230
- NAID
  130005143846
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-16K19183
[Journal Article] Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency2016
- Author(s)
  Ago Y, Hasebe S, Hiramatsu N, Mori K, Watabe Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Psychopharmacology(Berl)
  
  Volume: 233(17) Issue: 17 Pages: 3125-3134
- DOI
  10.1007/s00213-016-4353-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-16K08268, KAKENHI-PROJECT-16K15126, KAKENHI-PROJECT-16K19183
[Journal Article] The female encounter test, a novel method for evaluating reward-seeking behavior or motivation in mice2015
- Author(s)
  Ago Y, Hasebe S, Nishiyama S, Oka S, Onaka Y, Hashimoto H, Takuma K, Matsuda T.
- Journal Title
  
  Neuropsychopharmacol.
  
  Volume: 18(11) Issue: 11 Pages: pyv062-pyv062
- DOI
  10.1093/ijnp/pyv062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020
[Journal Article] Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice2015
- Author(s)
  Hasebe S, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Pharmacology
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099
[Journal Article] Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model2015
- Author(s)
  Hara Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 289 Pages: 39-47
- DOI
  10.1016/j.bbr.2015.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-13J05359
[Journal Article] Anxiolytic-like effects of restraint during the dark cycle in adolescent mice2015
- Author(s)
  Ota Y, Ago Y, Tanaka T, Hasebe S, Toratani Y, Onaka Y, Hashimoto H, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 284 Pages: 103-111
- DOI
  10.1016/j.bbr.2015.02.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-14J06155
[Journal Article] Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice2014
- Author(s)
  Araki R, Ago Y, Hasebe S, Nishiyama S, Tanaka T, Oka S, Takuma K, Matsuda T
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume: 17 Issue: 06 Pages: 883-893
- DOI
  10.1017/s1461145713001582
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-14J06155
[Journal Article] Social crowding in the night-time reduces an anxiety-like behavior and increases social interaction in adolescent mice2014
- Author(s)
  Ago Y, Tanaka T, Ota Y, Kitamoto M, Imoto E, Takuma K, Matsuda T
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 270 Pages: 37-46
- DOI
  10.1016/j.bbr.2014.04.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460099, KAKENHI-PROJECT-14J06155
[Journal Article] mGlu2/3 and mGlu5 receptors: Potential targets for novel antidepressants2013
- Author(s)
  Shigeyuki Chaki
- Journal Title
  
  Neuropharmacology
  
  Volume: 66 Pages: 40-52
- DOI
  10.1016/j.neuropharm.2012.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790599
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Pages: 351-354
- NAID
  10031171147
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] グリア細胞Na+/Ca2+交換系の病態生理学的役割2013
- Author(s)
  田熊一敞, 吾郷由希夫, 松田敏夫
- Journal Title
  
  生体の科学(医学書院)
  
  Volume: 64(5) Pages: 384-385
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] he glial sodium-calcium exchanger: a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T.
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121(4) Pages: 351-354
- NAID
  10031171147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The glial sodium-calcium exchanger: a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The glial sodium-calcium exchanger : a new target for nitric oxide-mediated cellular toxicity2013
- Author(s)
  Takuma K, Ago Y, Matsuda T
- Journal Title
  
  Curr Protein Pept Sci
  
  Volume: 14 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Role of social encounter-induced activation of prefrontal serotonergic systems in the abnormal behaviors of isolation-reared mice2013
- Author(s)
  Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsuda
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: Vol. 38 Issue: 8 Pages: 1535-1547
- DOI
  10.1038/npp.2013.52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460099
[Journal Article] Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells2013
- Author(s)
  Ota Y, Kawanai T, Watanabe R, Nishimura A, Ago Y, Takuma K, Matsuda T
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 121 Pages: 351-354
- NAID
  10031171147
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice.2013
- Author(s)
  Yukio Ago
- Journal Title
  
  Neuropharmacology
  
  Volume: 65 Pages: 29-38
- DOI
  10.1016/j.neuropharm.2012.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00450, KAKENHI-PROJECT-23790599
[Journal Article] The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide.2013
- Author(s)
  Ago Y
- Journal Title
  
  Behavioural Pharmacology
  
  Volume: 24(1) Issue: 1 Pages: 74-77
- DOI
  10.1097/fbp.0b013e32835cf3e5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790295, KAKENHI-PROJECT-23790599, KAKENHI-PROJECT-25460100
[Journal Article] グリア細胞Na+/Ca2+交換系の病態生理学的役割2013
- Author(s)
  田熊一敞，吾郷由希夫，松田敏夫
- Journal Title
  
  生体の科学
  
  Volume: 64 Pages: 384-385
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses isolation rearing-induced abnormal behaviors in mice.2012
- Author(s)
  Ago Y, Araki R, Yano K, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: Vol. 118 Pages: 295-298
- NAID
  10030455255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790599
[Journal Article] Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats2012
- Author(s)
  Takuma K, Tanaka T, Takahashi T, Hiramatsu N, Ota Y, Ago Y, Matsuda T
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 683(1-3) Pages: 166-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] The Selective Metabotropic Glutamate 2/3 Receptor Agonist MGS0028 Reverses Isolation Rearing-Induced Abnormal Behaviors in Mice2012
- Author(s)
  Yukio Ago, Ryota Araki, Koji Yano, Toshiyuki Kawasaki, Shigeyuki Chaki, Atsuro Nakazato, Hirotaka Onoe, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Issue: 2 Pages: 295-298
- DOI
  10.1254/jphs.11200SC
- NAID
  10030455255
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790599
[Journal Article] Involvement of decreased muscarinic receptor function in prepulse inhibition deficits in mice reared in social isolation2011
- Author(s)
  Ken Koda、Yukio Ago、Koji Yano、Momoe Nishimura、Hisako Kobayashi、Asako Fukada、Kazuhiro Takuma、Toshio Matsuda
- Journal Title
  
  British Journal of Pharmacology 162巻
  
  Pages: 763-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] Involvement of decreased muscarinic receptor function in prepulse inhibition deficits in mice reared in social isolation2011
- Author(s)
  Koda K, Ago Y, Yano K, Nishimura M, Kobayashi H, Fukada A, Takuma K, Matsuda T
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 162 Pages: 763-772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] Role of endogenous pituitary adenylate cyclase-activating polypeptide in adult hippocampal neurogenesis2011
- Author(s)
  Ago Y, Yoneyama M, Ishihama T, Kataoka S, Kawada K, Tanaka T, Ogita K, Shintani N, Hashimoto H, Baba A, Takuma K, Matsuda T
- Journal Title
  
  Neuroscience
  
  Volume: 172 Pages: 554-561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] SEA0400, a specific Na^+/Ca^<2+> exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease2011
- Author(s)
  Ago Y, et al
- Journal Title
  
  Neuropharmacology
  
  Volume: 61 Pages: 1441-1451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission.2011
- Author(s)
  Ago Y, Araki R, Yano K, Hiramatsu N, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: Vol. 217 Pages: 443-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790599
[Journal Article] SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease2011
- Author(s)
  Ago Y, Kawasaki T, Nashida T, Ota Y, Cong Y, Kitamoto M, Takahashi T, Takuma K, Matsuda T
- Journal Title
  
  Neuropharmacology
  
  Volume: 61(8) Pages: 1441-1451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390139
[Journal Article] Role of endogenous pituitary adenylate cyclase-activating polypeptide in adult hippocampal neurogenesis2011
- Author(s)
  Yukio Ago、Masanori Yoneyama、Toshihiro Ishihama、Shunsuke Kataoka、Koichi Kawada、Tetsuya Tanaka、Kiyokazu Ogita、Norihito Shintani、Hitoshi Hashimoto、Akemichi Baba、Kazuhiro Takuma、Toshio Matsuda
- Journal Title
  
  Neuroscience 172巻
  
  Pages: 554-561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] Role of endogenous pituitary adenylate cyclase-activating polypeptide in adult hippocampal neurogenesis2011
- Author(s)
  Yukio Ago
- Journal Title
  
  Neuroscience
  
  Volume: Vol.172 Pages: 554-561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659063
[Journal Article] Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission2011
- Author(s)
  Ago Y, Araki R, Yano K, Hiramatsu N, Kawasaki T, Chaki S, Nakazato A, Onoe H, Hashimoto H, Baba A, Takuma K, Matsuda T
- Journal Title
  
  Psychopharmacology (Berl)
  
  Volume: 217(3) Issue: 3 Pages: 443-52
- DOI
  10.1007/s00213-011-2295-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390069, KAKENHI-PROJECT-23790599
[Journal Article] 感覚情報処理機能障害に対するガランタミンの有効性とそのメカニズム2010
- Author(s)
  吾郷由希夫
- Journal Title
  
  薬学雑誌
  
  Volume: 130 Pages: 1305-1310
- NAID
  130000451673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] 感覚情報処理機能障害に対するガランタミンの有効性とそのメカニズム2010
- Author(s)
  吾郷由希夫
- Journal Title
  
  薬学雑誌 130巻
  
  Pages: 1305-1310
- NAID
  130000451673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] 感覚情報処理機能障害に対するガランタミンの有効性とそのメカニズム2010
- Author(s)
  吾郷由希夫
- Journal Title
  
  薬学雑誌
  
  Volume: 130巻 Pages: 1305-1310
- NAID
  130000451673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659063
[Journal Article] The Na^+/Ca^<2+> exchanger-mediated Ca^<2+> influx triggers nitric oxide-induced cytotoxicity in cultured astrocytes.2010
- Author(s)
  Tatsuya Kitao, Kazuhiro Takuma, Toshiyuki Kawasaki, Yuriko Inoue, Aki Ikehara, Tetsuaki Nashida, Yukio Ago, Toshio Matsuda
- Journal Title
  
  Neurochem.Int. 57
  
  Pages: 58-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390159
[Journal Article] Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice.2010
- Author(s)
  Toshihiro Ishihama、Yukio Ago、Norihito Shintani、Hitoshi Hashimoto、Akemichi Baba、Kazuhiro Takuma、Toshio Matsuda
- Journal Title
  
  Behavioural Brain Research 209巻
  
  Pages: 274-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] 代謝型グルタミン酸受容体と精神疾患2009
- Author(s)
  吾郷由希夫、川崎俊之
- Journal Title
  
  脳21 12巻
  
  Pages: 333-339
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] うっ病と副腎皮質ステロイドホルモン受容体2009
- Author(s)
  吾郷由希夫、田熊一敞、松田敏夫
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 304-308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] ガランタミンによるムスカリン性アセチルコリン受容体活性化の機構2009
- Author(s)
  吾郷由希夫、松田敏夫
- Journal Title
  
  生体の科学 60巻
  
  Pages: 408-409
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] うつ病と副腎皮質ステロイドホルモン受容体2009
- Author(s)
  吾郷由希夫、田熊一敞、松田敏夫
- Journal Title
  
  日本薬理学雑誌 134巻
  
  Pages: 304-308
- NAID
  10026334419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] Role of prefrontal dopaminergic neurotransmission in glucocorticoid receptor-mediated modulation of methamphetamine-induced hyperactivity2009
- Author(s)
  Ago Y, et al.
- Journal Title
  
  Synapse 63
  
  Pages: 7-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] 代謝型グルタミン酸受容体と精神疾患2009
- Author(s)
  吾郷由希夫、川崎俊之
- Journal Title
  
  脳21 12
  
  Pages: 333-339
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] ガランタミンによるムスカリン性アセチルコリン受容体活性化の機構2009
- Author(s)
  吾郷由希夫、松田敏夫
- Journal Title
  
  生体の科学 60
  
  Pages: 408-409
- Data Source
  KAKENHI-PROJECT-21790521
[Journal Article] 精神機能と環境因子2008
- Author(s)
  吾郷由希夫, 他.
- Journal Title
  
  脳21 11
  
  Pages: 81-87
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression2008
- Author(s)
  Ago Y, et al.
- Journal Title
  
  Neuropharmacology 55
  
  Pages: 1355-1363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Neuropsychotoxicity of abused drugs : Effects of serotonin receptor ligands onmethamphetamine- and cocaine-induced behabioral sensitization in mice.2008
- Author(s)
  Y. Ago, et al.
- Journal Title
  
  J. Pharmacol. Sci. 106
  
  Pages: 15-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390159
[Journal Article] メタンフェタミン誘発行動感作への前頭葉セロトニン神経系の関与2008
- Author(s)
  吾郷由希夫, 他.
- Journal Title
  
  日本神経精神薬理学雑誌 28
  
  Pages: 85-91
- NAID
  10023965457
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Neuropsychotoxicity of abused drugs:Effects of serotonin receptor ligands on methamphetamine- and cocaine-induces behavioral sensitization in mice.2008
- Author(s)
  Yukio Ago
- Journal Title
  
  Journal of Pharmacological Sciences 106
  
  Pages: 15-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothio-phen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), prevents 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.2008
- Author(s)
  Toshiyuki Kawasaki, Yukio Ago, Tatsuya Kitao, Tetsuaki Nashida, Akiko Takagi, Kazuhiro Takuma, Toshio Matsuda
- Journal Title
  
  Neuro-pharmacology 55(5)
  
  Pages: 654-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390159
[Journal Article] Neuropsychotoxicity of abused drugs: effects of serotonin receptor ligands on methamphetamine-and cocaine-induced behaviral sensitization in mice2008
- Author(s)
  Ago Y
- Journal Title
  
  J Pharmacol Sci 106
  
  Pages: 15-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Neuropsychotoxicity of abused drugs : effects of serotonin receptor ligands on methamphetamine- and cocaine-induced behavioral sensitization in mice2008
- Author(s)
  Ago Y, Nakamura S, Baba A, Matsuda T.
- Journal Title
  
  J Pharmacol Sci. 106
  
  Pages: 15-21
- NAID
  10024317275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Ritanserin reverses repeated methamphetamine-induced behavioral and neurochemical sensitization in mice.2007
- Author(s)
  Yukio Ago
- Journal Title
  
  Synapse 61
  
  Pages: 757-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test.2007
- Author(s)
  Yukio Ago
- Journal Title
  
  Journal of Pharmacological Sciences 104
  
  Pages: 153-158
- NAID
  10024314374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] 統合失調症とセロトニン1A受容体2007
- Author(s)
  吾郷由希夫
- Journal Title
  
  脳21 10(3)
  
  Pages: 44-48
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Anxiety-like and exploratory behaviors of isolation-reared mice in the staircase test2007
- Author(s)
  Ago Y
- Journal Title
  
  J Pharmacol Sci 104(2)
  
  Pages: 153-158
- NAID
  10024314374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] Rhanserin Reverses Repeated Methamphetamine-Induced Behavioral and Neurochemical Sensitization in Mice2007
- Author(s)
  Ago Y
- Journal Title
  
  Synapse 61
  
  Pages: 757-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390025
[Journal Article] 統合失調症とセロトニン_1A受容体.2007
- Author(s)
  吾郷由希夫
- Journal Title
  
  脳21 10
  
  Pages: 256-260
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice.2006
- Author(s)
  Yukio Ago
- Journal Title
  
  Pharmacology, Biochemistry and Behavior 85・1
  
  Pages: 198-205
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] Lack of enhanced effect of antipsychotics combined with fluvoxamine on acetylcholine release in rat prefrontal cortex.2006
- Author(s)
  Yukio Ago
- Journal Title
  
  Journal of Pharmacological Sciences 102・4
  
  Pages: 419-422
- NAID
  10020344789
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] Attenuation by the 5-HT_<1A> receptor agonist osemozotan of the behavioral effects of single and repeated methamphetamine in mice.2006
- Author(s)
  Yukio Ago
- Journal Title
  
  Neuropharmacology 51・4
  
  Pages: 914-922
- Data Source
  KAKENHI-PROJECT-18790365
[Journal Article] The specific Na^+/Ca^<2+> exchange inhibitor SEA0400 prevents nitric oxide-induced cytotoxicity in SH-SY5Y cells.
- Author(s)
  Tetsuaki Nashida, Kazuhiro Takuma, Sayoko Fukuda, Toshiyuki Kawasaki, Teisuke Takahashi, Akemichi Baba, Yukio Ago, Toshio Matsuda
- Journal Title
  
  Neurochem. Int. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390159
[Patent] 組成物2023
- Inventor(s)
  坂元孝太郎, 都英次郎, 吾郷由希夫, 中川晋作
- Industrial Property Rights Holder
  坂元孝太郎, 都英次郎, 吾郷由希夫, 中川晋作
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-223187
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20H03392
[Patent] 癌転移抑制用のVIPR2 アンタゴニストペプチド2023
- Inventor(s)
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Holder
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2023
- Data Source
  KAKENHI-PROJECT-23K09138
[Patent] 癌転移抑制用のＶＩＰＲ２アンタゴニストペプチド2022
- Inventor(s)
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Holder
  吾郷由希夫, 浅野智志, 坂元孝太郎
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-027791
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2の阻害が乳がんの細胞周期に与える影響2025
- Author(s)
  浅野智志, 小野亜美, 馬場楓, 上原輝, 坂元孝太郎, 早田敦子, 中澤敬信, 柳本惣市, 谷本幸太郎, 橋本均, 吾郷由希夫
- Organizer
  APPW2025（第130回日本解剖学会・第102回日本生理学会・第98回日本薬理学会合同大会）
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 統合失調症モデルマウスの認知機能障害を回復させるVIPR2阻害ペプチドKS-133の脳移行性製剤の開発2025
- Author(s)
  坂元孝太郎, 広川貴次, 金子皓, 横山玲, 中川晋作, 吾郷由希夫, 都英次郎
- Organizer
  日本薬学会第145年会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 神経ペプチド受容体VIPR2の阻害が乳がんの細胞周期に与える影響2025
- Author(s)
  浅野智志, 小野亜美, 馬場楓, 上原輝, 坂元孝太郎, 早田敦子, 中澤敬信, 柳本惣市, 谷本幸太郎, 橋本均, 吾郷由希夫
- Organizer
  APPW2025（第130回日本解剖学会・第102回日本生理学会・第98回日本薬理学会合同大会）
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] VIPR2選択的アンタゴニストペプチドの乳癌細胞周期チェックポイントに与える影響2024
- Author(s)
  浅野智志, 上原輝, 小野亜美, 吾郷由希夫
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 精神疾患・発達障害の創薬を目指した脳研究～マウスでみてきたこと～2024
- Author(s)
  吾郷由希夫
- Organizer
  第36回創薬・薬理フォーラム岡山
- Invited
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 血管作動性腸管ペプチド受容体2遺伝子のコピー数多型モデルマウスは超音波発声の変化と社会性行動の低下を示す2024
- Author(s)
  吾郷由希夫, 片平海雅, 陳露, 宮岡辰典, 北川航平, 横山玲, 竹内修斗, 山田めゐ, 金子皓, 石本憲司, 塚本智仁, 樋野展正, 中澤敬信, 橋本均, 中川晋作
- Organizer
  第54回日本神経精神薬理学会・第34回日本臨床精神神経薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 肥満時の歯周病はミクログリアの活性化を介して認知機能障害を引き起こす2024
- Author(s)
  吾郷由希夫, 駿河拓矢, 田村哲也, 山脇洋輔, 應原一久, 森岡徳光, 花本博, 大植香菜
- Organizer
  第146回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K09183
[Presentation] 統合失調症モデルに対する神経ペプチド受容体VIPR2遮断の新規薬理作用2024
- Author(s)
  古庵大地, 小野亜美, 浅野智志, 柴秀樹, 吾郷由希夫
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 統合失調症陽性症状モデルマウスに対する選択的VPAC2受容体アンタゴニストペプチドの作用2024
- Author(s)
  小野亜美, 今戸瑛二, 吾郷由希夫
- Organizer
  第41回日本障害者歯科学会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] Vasoactive intestinal peptide (VIP)をターゲットとしたマクロファージ貪食機能増強を介した抗腫瘍作用2024
- Author(s)
  西山成, 坂元孝太郎, 吾郷由希夫, Wararat Kittikulsuth
- Organizer
  第97回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] Overexpression of vasoactive intestinal peptide receptor 2 in neurons causes abnormal dendritic morphology in the prefrontal cortex and cognitive impairment2024
- Author(s)
  Ami Ono, Daichi Koan, Satoshi Asano, Tatsunori Miyaoka, Lu Chen, Shinsaku Nakagawa, Atsuko Hayata-Takano, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Kotaro Tanimoto, Yukio Ago
- Organizer
  The 35th World Congress Collegium Internationale Neuro-Psychopharmacologicum (CINP2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Overexpression of vasoactive intestinal peptide receptor 2 in neurons causes abnormal dendritic morphology in the prefrontal cortex and cognitive impairment2024
- Author(s)
  Ami Ono, Daichi Koan, Satoshi Asano, Tatsunori Miyaoka, Lu Chen, Shinsaku Nakagawa, Atsuko Hayata-Takano, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Kotaro Tanimoto, Yukio Ago
- Organizer
  The 35th World Congress Collegium Internationale Neuro-Psychopharmacologicum (CINP2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 統合失調症の新規創薬標的分子VIPR2の選択的アンタゴニストの開発2024
- Author(s)
  古庵大地, 小野亜美, 横山玲, 浅野智志, 柴秀樹, 吾郷由希夫
- Organizer
  第3回広島大学脳神経科学セミナー
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] ヒト口腔癌細胞の遊走における血管作動性腸管ペプチドシグナルの役割2024
- Author(s)
  上原輝, 浅野智志, 吾郷由希夫
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Regulation mechanisms and signaling pathways of VIPR2-mediated cancer progression2024
- Author(s)
  Satoshi Asano, Teru Uehara, Souichi Yanamoto, Yukio Ago
- Organizer
  第57回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] VIPR2選択的アンタゴニストペプチドの乳癌細胞周期チェックポイントに与える影響2024
- Author(s)
  浅野智志, 上原輝, 小野亜美, 吾郷由希夫
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Oral administration of Porphyromonas gingivalis to diet-induced obese mice impairs cognitive function2024
- Author(s)
  Kana Oue, Takuya Suruga, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Hiroshi Hanamato, Yukio Ago
- Organizer
  34th Annual Congress of the European College of Gerodontology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K09183
[Presentation] VIPR2特異的アンタゴニストとしての二環式中分子ペプチドKS-133の創製とマクロファージの極性変化による抗腫瘍効果2024
- Author(s)
  坂元孝太郎, 都英次郎, 中川晋作, 吾郷由希夫, 西山成
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 統合失調症モデルに対する神経ペプチド受容体VIPR2遮断の新規薬理作用2024
- Author(s)
  古庵大地, 小野亜美, 浅野智志, 柴秀樹, 吾郷由希夫
- Organizer
  第66回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] Regulation mechanisms and signaling pathways of VIPR2-mediated cancer progression2024
- Author(s)
  Satoshi Asano, Teru Uehara, Souichi Yanamoto, Yukio Ago
- Organizer
  第57回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-24K02185
[Presentation] 統合失調症の新規創薬標的分子VIPR2の選択的アンタゴニストの開発2024
- Author(s)
  古庵大地, 小野亜美, 横山玲, 浅野智志, 柴秀樹, 吾郷由希夫
- Organizer
  第3回広島大学脳神経科学セミナー
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] バルプロ酸の胎内曝露は中枢性感作と痛覚感受性の増大を引き起こす2023
- Author(s)
  吾郷由希夫, 田原孟, 今戸瑛二, 歌大介, 田熊一敞, 久米利明, 古武弥一郎, 浅野智志
- Organizer
  第44回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンの投与により回復する2023
- Author(s)
  竹本智哉, 馬場優志, 北川航平, 永安一樹, 勢力薫，早田敦子, 笠井淳司, 吾郷由希夫, 田熊一敞, 橋本亮太, 橋本均, 中澤敬信
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2の二量体化の機能的意義2023
- Author(s)
  浅野智志, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンの投与により回復する2023
- Author(s)
  竹本智哉, 馬場優志, 北川航平, 永安一樹, 勢力薫，早田敦子, 笠井淳司, 吾郷由希夫, 田熊一敞, 橋本亮太, 橋本均, 中澤敬信
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] Overexpression of VPAC2 receptors in the embryonic mouse central nervous system causes brain atrophy, increased white matter, and impaired sensorimotor gating2023
- Author(s)
  Yukio Ago, Allan J. MacKenzie-Graham, Hitoshi Hashimoto, James A. Waschek
- Organizer
  The 8th Congress of the Asian College of Neuropsychopharmacology (AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 精神疾患の治療を目指したVIPR2阻害剤の中分子創薬2023
- Author(s)
  吾郷由希夫, 山田めゐ, 宮岡辰典, 陳露, 石本憲司, 樋野展正, 中川晋作, 坂元孝太郎, 浅野智志
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2による乳癌細胞遊走・増殖の新たな制御機構2023
- Author(s)
  浅野智志, 坂元孝太郎, 吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 神経ペプチド受容体VIPR2による乳癌細胞遊走・増殖の新たな制御機構2023
- Author(s)
  浅野智志, 坂元孝太郎, 吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 血管作動性腸管ペプチド受容体2シグナルはERK経路を介した乳癌細胞増殖に関与している2023
- Author(s)
  浅野智志, 小野亜美, 坂元孝太郎, 早田敦子, 中澤敬信, 谷本幸太郎, 橋本均, 吾郷由希夫
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 神経ペプチド受容体VIPR2遺伝子のコピー数変異モデルマウスは超音波発声の変化と社会性行動の低下を示す2023
- Author(s)
  片平海雅, 陳露, 宮岡辰典, 北川航平, 竹内修斗, 山田めゐ, 金子皓, 石本憲司, 塚本智仁, 樋野展正, 中澤敬信, 橋本均, 中川晋作, 吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 二環式ペプチドKS-133とクラスB GPCR:VIPR2の結合メカニズム解明と機能的S-S結合の発見2023
- Author(s)
  坂元孝太郎, 浅野智志, 吾郷由希夫, 広川貴次
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Role of the VPAC2 receptor overactivation implicated in schizophrenia susceptibility2023
- Author(s)
  Ami Ono, Daichi Koan, Tatsunori Miyaoka, Satoshi Asano, Shinsaku Nakagawa, James A. Waschek, Kotaro Tanimoto, Yukio Ago
- Organizer
  第56回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 統合失調症の発症脆弱性の解明を目指した神経細胞特異的VIPR2過剰発現マウスモデルの開発2023
- Author(s)
  小野亜美, 古庵大地, 宮岡辰典, 浅野智志, 橋本均, 中川晋作, 谷本幸太郎, 吾郷由希夫
- Organizer
  第2回広島大学脳神経科学セミナー
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] VPAC2受容体を標的とした新規の中分子による統合失調症治療薬の創出2023
- Author(s)
  吾郷由希夫, 坂元孝太郎, 浅野智志
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 抗てんかん薬バルプロ酸の胎生期曝露は中枢性感作に伴う持続的な痛覚過敏とアロディニアを引き起こす2023
- Author(s)
  田原孟, 今戸瑛二, 歌大介, 浅野智志, 田熊一敞, 久米利明, 古武弥一郎, 吾郷由希夫
- Organizer
  フォーラム2023：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] (R)-ketamine enhances anterior insular cortex activity associated with social cognition2023
- Author(s)
  Rei Yokoyama, Yukio Ago, Masato Tanuma, Yuto Shimazaki, Kaoru Seiriki, Takanobu Nakazawa, Kenji Hashimoto, Atsushi Kasai, Hitoshi Hashimoto
- Organizer
  The 53rd Annual Meeting of the Society for Neuroscience (Neuroscience 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2の二量体化の機能的意義2023
- Author(s)
  浅野智志, 小野亜美, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] VPAC2受容体を標的とした新規の中分子による統合失調症治療薬の創出2023
- Author(s)
  吾郷由希夫, 坂元孝太郎, 浅野智志
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 治療抵抗性統合失調症の克服に向けた結合組織成長因子CTGFの役割と脳内デリバリー2023
- Author(s)
  吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 乳癌の増殖・転移における神経ペプチド受容体VIPR2 二量体化の機能的意義2023
- Author(s)
  浅野智志, 小野亜美, 上原輝, 谷本幸太郎, 柳本惣市, 吾郷由希夫
- Organizer
  第40回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 統合失調症の発症脆弱性因子としてのVPAC2受容体過活性化の役割―神経細胞特異的ヒトVPAC2受容体過剰発現マウスを用いた検討－2023
- Author(s)
  小野亜美, 今戸瑛二, 吾郷由希夫
- Organizer
  第40回日本障害者歯科学会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 統合失調症の発症脆弱性の解明を目指した神経細胞特異的VIPR2過剰発現マウスモデルの開発2023
- Author(s)
  小野亜美, 浅野智志, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] 血管作動性腸管ペプチド受容体2シグナルはERK経路を介した乳癌細胞増殖に関与している2023
- Author(s)
  浅野智志, 小野亜美, 坂元孝太郎, 早田敦子, 中澤敬信, 谷本幸太郎, 橋本均, 吾郷由希夫
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 胎生期中枢神経系におけるVPAC2受容体の過剰発現は脳の萎縮と白質の増加、感覚情報処理機能の障害を引き起こす2023
- Author(s)
  吾郷由希夫, Allan J. MacKenzie-Graham, 橋本均, James A. Waschek
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Modeling VIPR2 linkage to schizophrenia and developing antipsychotic medication2023
- Author(s)
  Yukio Ago
- Organizer
  Taiwanase Society of Biological Psychiatry and Neuropsychopharmacology (TSBPN) 2023 Annual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 二環式ペプチドKS-133とクラスB GPCR:VIPR2の結合メカニズム解明と機能的S-S結合の発見2023
- Author(s)
  坂元孝太郎, 浅野智志, 吾郷由希夫, 広川貴次
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Periodontal infection in diet-induced obesity causes cognitive impairment associated with microglial activation.2023
- Author(s)
  Kana Oue, Yusuke Morioka, Eiji Imado, Testuya Tamura, Yosuke Yamawaki, Kazuhisa Ouhara, Mitsuhiro Yoshida, Takashi Kanematsu, Yukio Ago
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K09183
[Presentation] Role of the VPAC2 receptor overactivation implicated in schizophrenia susceptibility2023
- Author(s)
  Ami Ono, Daichi Koan, Tatsunori Miyaoka, Satoshi Asano, Shinsaku Nakagawa, James A. Waschek, Kotaro Tanimoto, Yukio Ago
- Organizer
  第56回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 統合失調症の発症脆弱性の解明を目指した神経細胞特異的VIPR2過剰発現マウスモデルの開発2023
- Author(s)
  小野亜美, 浅野智志, 吾郷由希夫
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 非定型抗精神病薬クロザピンの認知機能障害改善作用における結合組織成長因子の関与2023
- Author(s)
  金子皓, 宮岡辰典, 山内良介, 竹内修斗, 河内琢也, 陳露, 片平海雅, 石本憲司, 樋野展正, 早田敦子, 中澤敬信, 田熊一敞, 中川晋作, 橋本均, 吾郷由希夫
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 統合失調症の新たな創薬標的分子：VPAC2受容体アンタゴニストペプチドの創製2023
- Author(s)
  吾郷由希夫
- Organizer
  第53回日本神経精神薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 乳癌の増殖・転移における神経ペプチド受容体VIPR2二量体化の機能的意義2023
- Author(s)
  浅野智志, 小野亜美, 上原輝, 谷本幸太郎, 柳本惣市, 吾郷由希夫
- Organizer
  第40回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-23K09138
[Presentation] Oxytocin restores abnormal social behavior in a mouse model of 3q29 microdeletion2023
- Author(s)
  Tomoya Takemoto, Kohei Kitagawa, Kazuki Nagayasu, Kaoru Seiriki, Atsuko Hayata-Takano, Atsushi Kasai, Yukio Ago, Kazuhiro Takuma, Daisuke Mori, Norio Ozaki, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa
- Organizer
  The 53rd Annual Meeting of the Society for Neuroscience (Neuroscience 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2はPI3K経路を介してがん細胞遊走を制御する2022
- Author(s)
  浅野智志, 吾郷由希夫
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Intranasal oxytocin administration suppresses social contact-induced neural activity in a POGZ-Q1038R mutant mouse model of autism spectrum disorder2022
- Author(s)
  Kohei Kitagawa, Masayuki Baba, Tomoya Takemoto, Masato Tanuma, Misuzu Hayashida, Shun Yamaguchi, Yukio Ago, Kaoru Seiriki, Atsuko Hayata-Takano, Kazuhiro Takuma, Atsushi Kasai, Hitoshi Hashimoto, Takanobu Nakazawa
- Organizer
  The 51st Annual Meeting of the Society for Neuroscience (Neuroscience 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] イミダゾールジペプチドの中枢作用に関する検討2022
- Author(s)
  山口稜太, 山口拓海, 中川晋作, 浅野智志, 松浦圭介, 中川正則, 吾郷由希夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] アールケタミンの抗うつ作用発現には島皮質が関与する2022
- Author(s)
  横山玲, 吾郷由希夫, 笠井淳司, 田沼将人, 林田美鈴, 島﨑雄人, 樋口桃子, 五十嵐久人, 勢力薫, 山口瞬, 中澤敬信, 橋本謙二, 橋本均
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 緑茶カテキン代謝物EGC-M5はマウスの認知機能障害と抑うつ様行動を軽減する2022
- Author(s)
  山口拓海, 片平海雅, 山口稜太, 石本憲司, 樋野展正, 高垣晶子, 大木渉吾, 鈴木壯幸, 中川晋作, 吾郷由希夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 鎮痛作用を示さない低用量μオピオイド受容体アゴニストは自閉スペクトラム症モデルマウスの社会性行動障害を改善する2022
- Author(s)
  吾郷由希夫, 内藤恵, 川瀬啓生, 樋口桃子, 山川英訓, 大波壮一郎, 小川公一, 中邨篤史, 河内貴弘, 今戸瑛二, 田原孟, 浅野智志, 古武弥一郎, 田熊一敞, 橋本均
- Organizer
  第44回日本生物学的精神医学会年会、第32回日本臨床精神神経薬理学会年会、第52回日本神経精神薬理学会年会、第6回日本精神薬学会総会・学術集会 4学会合同年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] TRPV1アンタゴニストAMG517は胎生期バルプロ酸投与誘発の自閉症モデルマウスにおいて痛覚感受性の異常と社会性行動障害を改善する2022
- Author(s)
  田原孟, 今戸瑛二, 川瀬啓生, 樋口桃子, 山川英訓, 小川公一, 古武弥一郎, 田熊一敞, 橋本均, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] Claustrum mediates stress-induced anxiety responses and stress resistance2022
- Author(s)
  Hitoshi Hashimoto, Misaki Niu, Masato Tanuma, Kaoru Seiriki, Yukio Ago, Shun Yamaguchi, Atsushi Kasai
- Organizer
  The 61st Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Activation of the rostral agranular insular cortex is involved in the antidepressant actions of arketamine2022
- Author(s)
  Yukio Ago, Rei Yokoyama, Atsushi Kasai, Masato Tanuma, Misuzu Hayashida, Yuto Shimazaki, Momoko Higuchi, Hisato Igarashi, Kaoru Seiriki, Shun Yamaguchi, Takanobu Nakazawa, Kenji Hashimoto, Hitoshi Hashimoto
- Organizer
  The 61st Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] アールケタミンの抗うつ作用発現には島皮質が関与する2022
- Author(s)
  横山玲, 吾郷由希夫, 笠井淳司, 田沼将人, 林田美鈴, 島﨑雄人, 樋口桃子, 五十嵐久人, 勢力薫, 山口瞬, 中澤敬信, 橋本謙二, 橋本均
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] マウス胎生期のバルプロ酸曝露は脊髄でのミクログリアの増殖とアロディニアを引き起こす2022
- Author(s)
  吾郷由希夫, 今戸瑛二, Samnang Sun, 中村庸輝, 中島一恵, 森岡徳光, 田熊一敞, 木口倫一, 浅野智志
- Organizer
  Neuro2022 (第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] Intranasal oxytocin administration suppresses social contact-induced neural activity in a POGZ-Q1038R mutant mouse model of autism spectrum disorder2022
- Author(s)
  Kohei Kitagawa, Masayuki Baba, Tomoya Takemoto, Masato Tanuma, Misuzu Hayashida, Shun Yamaguchi, Yukio Ago, Kaoru Seiriki, Atsuko Hayata-Takano, Kazuhiro Takuma, Atsushi Kasai, Hitoshi Hashimoto, Takanobu Nakazawa
- Organizer
  The 51st Annual Meeting of the Society for Neuroscience (Neuroscience 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 自閉スペクトラム症の新しい治療戦略：社会性障害の回復機構における脳部位特異的オピオイドシステムバランスの役割2022
- Author(s)
  吾郷由希夫
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 自閉スペクトラム症の病態基盤解明と創薬を目指して2022
- Author(s)
  吾郷由希夫
- Organizer
  第39回日本障害者歯科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Abnormal pain sensitivity associated with spinal microglial activation in a prenatal valproic acid-induced mouse model of autism2022
- Author(s)
  Eiji Imado, Sun Samnang, Abrar Rizal Abawa, Satoshi Asano, Kazuhiro Tsuga, Masahiro Irifune, Yukio Ago
- Organizer
  第55回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] TRPV1アンタゴニストAMG517は胎生期バルプロ酸投与誘発の自閉症モデルマウスにおいて痛覚感受性の異常と社会性行動障害を改善する2022
- Author(s)
  田原孟, 今戸瑛二, 川瀬啓生, 樋口桃子, 山川英訓, 小川公一, 古武弥一郎, 田熊一敞, 橋本均, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] A potential role of neuropeptide receptor VIPR2 signaling in tumor cell migration2022
- Author(s)
  Satoshi Asano, Misa Yamasaka, Kairi Ozasa, James Waschek, Yukio Ago
- Organizer
  第55回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経発達障害モデルマウスにおける機械的アロディニアの発症とミクログリアの関与2022
- Author(s)
  今戸瑛二, Samnang Sun, Abawa Abrar, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 木口倫一, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] ASDモデルマウスの社会性行動と前頭前皮質の機能異常2022
- Author(s)
  笠井淳司, 彌永祐輔, 植野寛貴, 中井悠花, 原雄大, 三浦大樹, 田沼将人, 林田美鈴, 横山玲, 大久保仁, 勢力薫, 早田-高野敦子, 山口瞬, 北岡志保, 古屋敷智之, 吾郷由希夫, 中澤敬信, 田熊一敞, 橋本均
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Agranular insular cortex mediates the antidepressant actions of arketamine2022
- Author(s)
  Rei Yokoyama, Yukio Ago, Atsushi Kasai, Masato Tanuma, Misuzu Hayashida, Yuto Shimazaki, Momoko Higuchi, Hisato Igarashi, Kaoru Seiriki, Shun Yamaguchi, Takanobu Nakazawa, Kenji Hashimoto, Hitoshi Hashimoto
- Organizer
  The 51st Annual Meeting of the Society for Neuroscience (Neuroscience 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 胎生期のヒストン脱アセチル化酵素阻害は脊髄ミクログリアの活性化と機械的アロディニアを引き起こす2022
- Author(s)
  今戸瑛二, Sun Samnang, Huynh Ngoc Bao Tran, 中村庸輝, 中島一恵, 森岡徳光, 木口倫一, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 胎生期のヒストン脱アセチル化酵素阻害は脊髄ミクログリアの活性化と機械的アロディニアを引き起こす2022
- Author(s)
  今戸瑛二, Sun Samnang, Huynh Ngoc Bao Tran, 中村庸輝, 中島一恵, 森岡徳光, 木口倫一, 浅野智志, 吾郷由希夫
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 神経ペプチドVIPはVPAC2受容体を介するPI3K経路の活性化により細胞遊走を引き起こす2022
- Author(s)
  小笹かいり, 浅野智志, 山坂美紗, 早田敦子, 中澤敬信, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Abnormal pain sensitivity associated with spinal microglial activation in a prenatal valproic acid-induced mouse model of autism2022
- Author(s)
  Eiji Imado, Sun Samnang, Abrar Rizal Abawa, Satoshi Asano, Kazuhiro Tsuga, Masahiro Irifune, Yukio Ago
- Organizer
  第55回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] KS-133, a novel peptide antagonist targeting VIPR2 for the treatment of schizophrenia2022
- Author(s)
  Yukio Ago, Kotaro Sakamoto, Satoshi Asano
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 自閉スペクトラム症モデルマウスにおける持続的なアロディニアの発現と脊髄内ミクログリア活性化の関与2022
- Author(s)
  今戸瑛二, 入舩正浩, 吾郷由希夫
- Organizer
  第50回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] マウス胎生期のバルプロ酸曝露は脊髄でのミクログリアの増殖とアロディニアを引き起こす2022
- Author(s)
  吾郷由希夫, 今戸瑛二, Samnang Sun, 中村庸輝, 中島一恵, 森岡徳光, 田熊一敞, 木口倫一, 浅野智志
- Organizer
  Neuro2022 (第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会合同大会)
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Neuron-specific overexpression of human VPAC2 receptors in mice causes cognitive dysfunction2022
- Author(s)
  Ami Ono, Daichi Koan, Satoshi Asano, Tatsunori Miyaoka, Lu Chen, Mei Yamada, Shinsaku Nakagawa, Atsuko Hayata-Takano, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 自閉スペクトラム症の病態基盤解明と創薬を目指して2022
- Author(s)
  吾郷由希夫
- Organizer
  第39回日本障害者歯科学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] Impaired neurodevelopment in iPS cell-derived neural stem cells from psychiatric patients with 7q36.3 microduplication2022
- Author(s)
  Kohei Kitagawa, Masayuki Baba, Tomoya Takemoto, Kazuki Nagayasu, Atsushi Kasai, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Yukio Ago, Takanobu Nakazawa
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 自閉スペクトラム症の新しい治療戦略：社会性障害の回復機構における脳部位特異的オピオイドシステムバランスの役割2022
- Author(s)
  吾郷由希夫
- Organizer
  第96回日本薬理学会年会・第43回日本臨床薬理学会学術総会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] PLC様タンパク質PRIP1のPH domain内包リポソームはシスプラチン耐性乳ガン細胞のアポトーシス細胞死を促進する2022
- Author(s)
  浅野智志, 吾郷由希夫, 兼松隆
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 自閉スペクトラム症モデルマウスにおける持続的なアロディニアの発現と脊髄内ミクログリア活性化の関与2022
- Author(s)
  今戸瑛二, 入舩正浩, 吾郷由希夫
- Organizer
  第50回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 静脈麻酔から覚醒後の悪心・嘔吐におけるラット延髄最後野のドーパミン神経とセロトニン神経の関与―行動薬理学実験及び脳マイクロダイアリシス法による検討―2022
- Author(s)
  佐々木詩佳，入舩正浩，今戸瑛二，本池芹佳，小田綾，大植香菜，吉田充広，吾郷由希夫
- Organizer
  第50回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K10139
[Presentation] 抗うつ薬・抗うつ薬候補の反応性からみるモデル動物の役割2022
- Author(s)
  吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] The VIP/VIPR2 pathway regulates breast cancer cell migration2022
- Author(s)
  Satoshi Asano, Misa Yamasaka, Kairi Ozasa, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  VPAC ISBAP 2022 (Joint symposium of the 1st Meeting of the International Society for Bioactive Peptides and the 15th International Symposium on VIP, PACAP and Related Peptides)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 抗うつ薬・抗うつ薬候補の反応性からみるモデル動物の役割2022
- Author(s)
  吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] Possible role of histone deacetylase inhibition in tactile hypersensitivity in a mouse model of autism spectrum disorder2022
- Author(s)
  Samnang Sun, Eiji Imado, Tran Ngoc Bao Huynh, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Norikazu Kiguchi, Satoshi Asano, Yukio Ago
- Organizer
  第37回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 神経ペプチド受容体VIPR2のオリゴマー化とその機能的意義2022
- Author(s)
  浅野智志, 小笹かいり, 中澤敬信, Waschek James, 吾郷由希夫
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 鎮痛作用を示さない低用量μオピオイド受容体アゴニストは自閉スペクトラム症モデルマウスの社会性行動障害を改善する2022
- Author(s)
  吾郷由希夫, 内藤恵, 川瀬啓生, 樋口桃子, 山川英訓, 大波壮一郎, 小川公一, 中邨篤史, 河内貴弘, 今戸瑛二, 田原孟, 浅野智志, 古武弥一郎, 田熊一敞, 橋本均
- Organizer
  第44回日本生物学的精神医学会年会、第32回日本臨床精神神経薬理学会年会、第52回日本神経精神薬理学会年会、第6回日本精神薬学会総会・学術集会 4学会合同年会（BPCNPNPPP4学会合同年会）
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Agranular insular cortex mediates the antidepressant actions of arketamine2022
- Author(s)
  Rei Yokoyama, Yukio Ago, Atsushi Kasai, Masato Tanuma, Misuzu Hayashida, Yuto Shimazaki, Momoko Higuchi, Hisato Igarashi, Kaoru Seiriki, Shun Yamaguchi, Takanobu Nakazawa, Kenji Hashimoto, Hitoshi Hashimoto
- Organizer
  The 51st Annual Meeting of the Society for Neuroscience (Neuroscience 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Activation of the rostral agranular insular cortex is involved in the antidepressant actions of arketamine2022
- Author(s)
  Yukio Ago, Rei Yokoyama, Atsushi Kasai, Masato Tanuma, Misuzu Hayashida, Yuto Shimazaki, Momoko Higuchi, Hisato Igarashi, Kaoru Seiriki, Shun Yamaguchi, Takanobu Nakazawa, Kenji Hashimoto, Hitoshi Hashimoto
- Organizer
  The 61st Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 自閉スペクトラム症モデルマウスにおける持続的なアロディニアの発現と脊髄内ミクログリア活性化の関与2022
- Author(s)
  今戸瑛二，入舩正浩，吾郷由希夫
- Organizer
  第50回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K10139
[Presentation] 統合失調症治療を目指したクラスB GPCR VIPR2アンタゴニストペプチドの薬理学的研究2022
- Author(s)
  吾郷由希夫, 坂元孝太郎
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Possible role of histone deacetylase inhibition in tactile hypersensitivity in a mouse model of autism spectrum disorder2022
- Author(s)
  Samnang Sun, Eiji Imado, Tran Ngoc Bao Huynh, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Norikazu Kiguchi, Satoshi Asano, Yukio Ago
- Organizer
  第37回創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 新規選択的VPAC2受容体アンタゴニストペプチドの創製とその中枢薬理作用2021
- Author(s)
  山田めゐ, 陳露, 宮岡辰典, 桝谷晃明, 石本憲司, 樋野展正, 中川晋作, 浅野智志, 坂元孝太郎, 吾郷由希夫
- Organizer
  第140回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 胎生期バルプロ酸投与マウスは熱刺激およびカプサイシン誘発痛の増大と機械的アロディニアを示す2021
- Author(s)
  今戸瑛二, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 吾郷由希夫
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K10139
[Presentation] A potent and highly selective VPAC2 receptor antagonist peptide KS-133 counteracts cognitive impairment in a mouse model relevant to schizophrenia2021
- Author(s)
  Yukio Ago, Lu Chen, Tatsunori Miyaoka, Mei Yamada, Teruaki Masutani, Kenji Ishimoto, Shinsaku Nakagawa, Satoshi Asano, Kotaro Sakamoto
- Organizer
  The 60th Annual Meeting of the American College of Neuropsychopharmacology (ACNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Abnormal pain sensitivity in a prenatal valproic acid-induced mouse model of autism spectrum disorder2021
- Author(s)
  Eiji Imado, Sun Samnang, Abrar Rizal Abawa, Satoshi Asano, Kazuhiro Tsuga, Masahiro Irifune, Yukio Ago
- Organizer
  The 6th Joint Scientific Meeting in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 精神疾患の創薬を目指した脳研究～マウスでみてきたこと～2021
- Author(s)
  吾郷由希夫
- Organizer
  第40回躁うつ病の薬理・生化学的研究懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 精神疾患の創薬を目指した脳研究～マウスでみてきたこと～2021
- Author(s)
  吾郷由希夫
- Organizer
  第40回躁うつ病の薬理・生化学的研究懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19714
[Presentation] 7q36.3領域微小重複を有する精神疾患患者のiPS細胞由来分化神経幹細胞を用いた分子病態解析2021
- Author(s)
  北川航平, 馬場優志, 竹本智哉, 永安一樹, 笠井淳司, 橋本亮太, 橋本均, 吾郷由希夫, 中澤敬信
- Organizer
  生体機能と創薬シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンの投与により回復する2021
- Author(s)
  竹本智哉, 馬場優志, 北川航平, 永安一樹, 勢力薫, 早田敦子, 笠井淳司, 吾郷由希夫, 田熊一敞,　橋本均, 中澤敬信
- Organizer
  第140回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Overexpression of VIPR2 in neurons causes defects in dendritic growth and cognitive impairment2021
- Author(s)
  Tatsunori Miyaoka, Lu Chen, Mei Yamada, Daichi Koan, Satoshi Asano, Kenji Ishimoto, Shinsaku Nakagawa, Atsuko Hayata, Takanobu Nakazawa, Akihiro Harada, Hitoshi Hashimoto, James A. Waschek, Yukio Ago
- Organizer
  The 7th Congress of the Asian College of Neuropsychopharmacology (AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] レアバリアントから迫る精神疾患の病態解明と創薬研究2021
- Author(s)
  吾郷由希夫
- Organizer
  第36回創薬・薬理フォーラム岡山
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 生体内で薬効を示す VIPR2 選択的アンタゴニストペプチドの創製2021
- Author(s)
  坂元孝太郎, 吾郷由希夫
- Organizer
  第16回GPCR研究会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 7q36.3領域微小重複を有する精神疾患患者のiPS細胞由来分化神経幹細胞を用いた分子病態解析2021
- Author(s)
  北川航平, 馬場優志, 竹本智哉, 永安一樹, 笠井淳司, 橋本亮太, 橋本均, 吾郷由希夫, 中澤敬信
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] ヒトVPAC2受容体の過剰発現を細胞種特異的かつ時空間的に制御可能な新しいトランスジェニックマウスモデルの開発2021
- Author(s)
  宮岡辰典, 陳露, 山田めゐ, 古庵大地, 浅野智志, 石本憲司, 中川晋作, 早田敦子, 中澤敬信, 原田彰宏, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 脳神経細胞でのVPAC2受容体の過剰発現は認知機能障害を引き起こす2021
- Author(s)
  古庵大地, 今戸瑛二, 浅野智志, Chen Lu, 宮岡辰典, 山田めゐ, 石本憲司, 中川晋作, 早田敦子, 中澤敬信, 原田彰宏, 橋本均, Waschek James, 吾郷由希夫
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 胎生期バルプロ酸投与マウスは熱刺激およびカプサイシン誘発痛の増大と機械的アロディニアを示す2021
- Author(s)
  今戸瑛二, 浅野智志, 中村庸輝, 中島一恵, 森岡徳光, 津賀一弘, 入舩正浩, 田熊一敞, 吾郷由希夫
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] オキシトシンの鼻腔内投与はPOGZ-Q1038R点変異マウスの社会性行動異常を改善する2021
- Author(s)
  北川航平, 松村憲佑, 馬場優志, 近藤百香, 竹本智哉, 永安一樹, 吾郷由希夫, 笠井淳司, 田熊一敞, 橋本均, 中澤敬信
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] ヒト染色体3q29欠失モデルマウスを用いた精神疾患の分子病態研究2020
- Author(s)
  馬場優志, 勢力薫, 近藤百香, 北川航平, 竹本智哉, 笠井淳司, 吾郷由希夫, 永安一樹, 森大輔, 尾崎紀夫, 山本雅, 田熊一敞, 橋本亮太, 橋本均, 中澤敬信
- Organizer
  第138回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] Behavioral and morphological abnormalities in a mouse model with copy number variation of the vasoactive intestinal peptide receptor VIPR2 gene2020
- Author(s)
  陳露, 竹内修斗, 山田めゐ, 宮岡辰典, 山口拓海, 中澤敬信, 中川晋作, 橋本均, 吾郷由希夫
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 妊娠期の薬物服用に起因する自閉スペクトラム症の病態解明2020
- Author(s)
  田熊一敞, 原雄大, 吾郷由希夫, 橋本均, 中澤敬信, 松田敏夫
- Organizer
  第50回日本神経精神薬理学会年会, 第42回日本生物学的精神医学会年会, 第4回日本精神薬学会総会・学術集会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] レアバリアントから迫る統合失調症の病態分子基盤と創薬戦略2020
- Author(s)
  吾郷由希夫
- Organizer
  第163回日本獣医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03392
[Presentation] 動物モデルを用いた精神疾患の病態メカニズム解析と創薬基盤研究2019
- Author(s)
  吾郷由希夫
- Organizer
  一般社団法人予防薬理学研究所キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] Effects of intranasal oxytocin on autism-like behavioral abnormalities in valproic acid-induced mouse model of autism2018
- Author(s)
  Yuta Hara, Yukio Ago, Momoko Higuchi, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] ブチリルコリンエステラーゼ阻害剤は内因性グレリンシグナルを促進して認知機能障害を改善する：ムスカリンM1受容体との機能的相互作用の関与.2018
- Author(s)
  塚田信司, 東野功典, 国本寿美子, Nigel H. Greig, 橋本均, 中川晋作, 吾郷由希夫
- Organizer
  第24回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] Inhibition of butyrylcholinesterase improves prepulse inhibition deficits and enhances M1 muscarinic acetylcholine receptor-mediated responses via ghrelin signaling in mice.2018
- Author(s)
  Tsukada S, Higashino K, Kunimoto S, Greig NH, Matsuda T, Hashimoto H, Ago Y
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] Selective serotonin reuptake inhibitors with affinity for σ1 receptors exert anti-anhedonic effect in picrotoxin-induced model of anxiety/depression2017
- Author(s)
  吾郷由希夫, 長谷部茂, 樋口桃子, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] ブチリルコリンエステラーゼ阻害によるグレリンシグナルの活性化を介した中枢ムスカリンM1受容体機能の亢進2017
- Author(s)
  吾郷由希夫, 東野功典, 国本寿美子, 塚田信司, Nigel H. Greig, 松田敏夫, 橋本均
- Organizer
  第14回GPCR研究会
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] メタンフェタミン退薬時の社会的刺激による多動反応と前頭前野セロトニン、ドパミン神経系の活性化2017
- Author(s)
  梅原千晶, 吾郷由希夫, 田中辰典, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎パブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] ブチリルコリンエステラーゼ阻害によるプレパルスインヒビション障害の改善：グレリンシグナルを介したムスカリンM1受容体機能亢進の関与2017
- Author(s)
  吾郷由希夫, 東野功典, 国本寿美子, 塚田信司, Nigel Greig, 松田敏夫, 橋本均
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] ドパミン神経賦活薬の慢性投与は胎仔期バルプロ酸曝露マウスの自閉症様行動を改善する2016
- Author(s)
  長谷部茂, 原雄大, 樋口桃子, 吾郷由希夫, 中澤敬信, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場 (福岡県福岡市)
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] マウスエンカウンター試験を用いた覚せい剤精神病のストレス再燃の解析2016
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常～ADHD治療薬による行動異常の改善2016
- Author(s)
  吾郷由希夫, 原雄大, 前田優子, 長谷部茂, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第46回日本神経精神薬理学会年会
- Place of Presentation
  ソウル市, 韓国
- Year and Date
  2016-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 雌性マウスを用いた意欲・報酬探索行動評価試験2016
- Author(s)
  川瀬啓生, 吾郷由希夫, 長谷部茂, 岡智史, 田熊一敞, 松田敏夫, 橋本均
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館 (広島県広島市)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 精神的ストレスによる覚せい剤精神病の再燃現象におけるセロトニン受容体の関与2016
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 長谷部茂, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第13回GPCR研究会
- Place of Presentation
  日本科学未来館
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] Continuous activation of dopaminergic system improves autism-related behavioral abnormalities in mice prenatally exposed to valproic acid2016
- Author(s)
  Hasebe S, Hara Y, Higuchi M, Ago Y, Nakazawa T, Hashimoto H, Matsuda T, Takuma K
- Organizer
  The 46th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15126
[Presentation] 雌性マウスを用いた意欲・報酬探索行動評価試験2016
- Author(s)
  川瀬啓生, 吾郷由希夫, 長谷部茂, 岡智史, 田熊一敞, 松田敏夫, 橋本均
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K08268
[Presentation] 雌選択性試験：マウス間相互作用を基盤とした新規うつ様行動評価系2015
- Author(s)
  長谷部茂, 岡智史, 尾中勇祐, 橋本均, 松田敏夫, 吾郷由希夫, 田熊一敞
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 雌雄エンカウンター刺激を用いた新規マウス意欲評価系2015
- Author(s)
  長谷部茂, 吾郷由希夫, 岡智史, 尾中勇祐, 橋本均, 松田敏夫, 田熊一敞
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] メタンフェタミン反復投与マウスの精神的ストレスによる多動反応の神経化学的基盤2015
- Author(s)
  田中辰典, 吾郷由希夫, 梅原千晶, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Development of a novel method for assessing motivation in male mice2015
- Author(s)
  Hasebe S, Ago Y, Oka S, Onaka Y, Hashimoto H, Matsuda T, Takuma K
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] エンカウンター刺激を利用した新規マウス意欲評価試験の開発2015
- Author(s)
  長谷部茂, 吾郷由希夫, 岡智史, 渡部雄二, 尾中勇祐, 橋本均, 田熊一敞, 松田敏夫
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] マウス活動期における拘束ストレスは抗不安様作用を示す2015
- Author(s)
  田中辰典, 太田友樹, 大住康晃, 長谷部茂, 尾中勇祐, 橋本均, 松田敏夫, 田熊一敞, 吾郷由希夫
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 抗うつ薬による長期隔離飼育マウスのエンカウンター誘発多動反応抑制の作用機序2014
- Author(s)
  岡智史, 長谷部茂, 西山早紀, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 隔離飼育マウスのエンカウンター誘発多動に対する抗うつ薬の多動抑制メカニズム2014
- Author(s)
  長谷部茂, 西山早紀, 岡智史, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 過密飼育環境の夜間負荷による発育期マウス精神機能の変化2014
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 北本真理, 太田友樹, 田熊一敞, 松田敏夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] セロトニン1A受容体による中枢神経機能制御に関する薬理学的研究2014
- Author(s)
  吾郷由希夫
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  東北大学川内萩ホール、仙台国際センター(宮城)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター刺激による多動発現におけるAMPA受容体の関与2014
- Author(s)
  荒木良太, 吾郷由希夫, 矢部武士, 田熊一敞, 松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2014
- Place of Presentation
  近畿大学（東大阪）
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのうつ病モデルマウスとしての薬理学的有用性2014
- Author(s)
  西山早紀, 長谷部茂, 吾郷由希夫, 岡　智史, 田熊一敞, 松田敏夫
- Organizer
  第64回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神刺激薬反復投与マウスのマウス間相互作用の異常2014
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 田熊一敞, 松田敏夫
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応の薬理学的プロファイル2014
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 中森大貴, 田熊一敞, 松田敏夫
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのマウス間相互作用応答性異常の神経化学的基盤2013
- Author(s)
  荒木良太,吾郷由希夫,笹賀あすか,西山早紀,田熊一敞,松田敏夫
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 精神障害モデルマウスにおける個体間相互作用応答性の異常2013
- Author(s)
  田中辰典、長谷部茂、吾郷由希夫、荒木良太、西山早紀、井本絵実奈、田熊一敞、松田敏夫
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター(沖縄)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 神経精神作用薬標的分子の創薬的意義に関する神経化学的研究2013
- Author(s)
  吾郷由希夫
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター(沖縄)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神疾患モデルマウスにおけるエンカウター刺激による前頭葉モノアミン神経変化と行動異常発現へのAMPA受容体の関与2013
- Author(s)
  西山早紀、荒木良太、吾郷由希夫、田中辰典、田熊一敞、松田敏夫
- Organizer
  第63回日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学(京都)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神疾患モデルへのエンカウンター刺激による長期隔離マウス行動異常発現におけるAMPA受容体の役割2013
- Author(s)
  西山早紀、荒木良太、吾郷由希夫、田中辰典、長谷部茂、田熊一敞、松田敏夫
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都ガーデンパレス(京都)
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神的マウス間相互作用による長期隔離飼育マウスの前頭前野セロトニン神経活性化2013
- Author(s)
  荒木良太,吾郷由希夫,笹賀あすか,西山早紀,田熊一敞,松田敏夫
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Neurochemical and behavioral responses of psychiatric disorder model mice to social encounter2013
- Author(s)
  Kazuhiro Takuma, Shigeru Hasebe, Tatsunori Tanaka, Saki Nishiyama, Yuko Maeda, Ryota Araki, Yukio Ago, Toshio Matsuda
- Organizer
  The 43rd annual meeting of the Society for Neuroscience (Neuroscience 2013)
- Place of Presentation
  San Diego Convention Center （San Diego, USA）
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] PACAP 遺伝子欠損マウスの異常行動に対する自発運動の作用2013
- Author(s)
  中川光, 福山留以, 山口浩史, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] Antidepressant-like effect of LY341495 a metabotropic glutamate 2/3 receptor antagonist, in the chronic corticosterone-treated mice, an animal model of treatment-resistant depression.2012
- Author(s)
  Yukio Ago, Koji Yano, Ryota Araki, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  The 42nd annual meeting of the Society for Neuroscience (Neuroscience 2012)
- Place of Presentation
  New Orleans (USA)
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] コルチコステロン慢性投与マウスのうつ様行動と大脳皮質ドパミン神経機能に対する代謝型グルタミン酸2/3受容体アンタゴニストの作用2012
- Author(s)
  矢野耕史,吾郷由希夫,荒木良太,平松直樹,田熊一敞,松田敏夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 6-Hydroxydopamine 神経障害ラットにおけるL-DOPA 誘発ジスキネジアの形成に対する神経型一酸化窒素合成酵素阻害薬7-nitroindazole の改善効果2012
- Author(s)
  太田友樹, 田熊一敞, 高橋剛士, 吾郷由希夫, 松田敏夫
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 長期隔離飼育マウスの異常行動発現におけるAMPA受容体の関与2012
- Author(s)
  笹賀あすか,荒木良太,吾郷由希夫,田熊一敞,松田敏夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 発育期環境要因のマウス精神機能発達に対する作用2012
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 北本真理, 田熊一敞, 松田敏夫
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] Antidepressant-like effect of LY341495, a metabotropic glutamate 2/3 receptor antagonist, in the chronic corticosterone-treated mice, an animal model of treatment-resistant depression2012
- Author(s)
  Yukio Ago
- Organizer
  The 42nd annual meeting of the Society for Neuroscience
- Place of Presentation
  Ernest N. Morial Convention Center (New Orleans, USA)
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 代謝型グルタミン酸2/3受容体作動薬による精神疾患病態モデルマウス異常行動の改善とその神経化学的基盤2012
- Author(s)
  吾郷由希夫,荒木良太,橋本均,田熊一敞,松田敏夫
- Organizer
  第9回GPCR研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 長期隔離飼育マウスの神経科学的コミュニケーション異常2012
- Author(s)
  荒木良太,吾郷由希夫,笹賀あすか,西山早紀,田熊一敞,松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2012
- Place of Presentation
  神戸
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] PACAP 欠損マウスの学習記憶障害に対する豊かな環境飼育の影響2012
- Author(s)
  福山留以, 竹本光佑, 中川光, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 社会的相互作用ストレスによる長期隔離飼育マウス前頭前野のモノアミン遊離と神経活性化2012
- Author(s)
  荒木良太,吾郷由希夫,笹賀あすか,田熊一敞,松田敏夫
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] レボドパ誘発ジスキネジア形成過程における神経型一酸化窒素合成酵素の役割2012
- Author(s)
  田熊一敞, 田中辰典, 高橋剛士, 太田友樹, 平松直樹, 吾郷由希夫, 松田敏夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] 代謝型グルタミン酸2/3受容体作動薬による精神疾患病態モデルマウス異常行動の改善とその神経化学的基盤2012
- Author(s)
  吾郷　由希夫
- Organizer
  第9回GPCR研究会
- Place of Presentation
  日本科学未来館（東京都）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 幼若期環境強化によるPACAP 遺伝子欠損マウス学習記憶障害の発現抑制2012
- Author(s)
  中川光, 竹本光佑, 福山留以, 新谷紀人, 橋本均, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] コルチコステロン慢性投与マウスのうつ様行動と大脳皮質ドパミン神経機能に対する代謝型グルタミン酸2/3受容体アンタゴニストの作用2012
- Author(s)
  矢野耕史、吾郷由希夫、荒木良太、平松直樹、田熊一敞、松田敏夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Involvement of prefrontal AMPA receptors in aggressive behavior and cognitive impairment of social isolation-reared mice2011
- Author(s)
  Ryota Araki, Asuka Sasaga, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  The 41th annual meeting of the Society for Neuroscience (Neuroscience 2011)
- Place of Presentation
  Walter E. Washington Convention Center （Washigton DC, USA）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Antidepressant-like effect of a metabotropic glutamate 2/3 receptor antagonist.2011
- Author(s)
  Yukio Ago, Shigeyuki Chaki, Kazuhiro Takuma, Toshio Matsuda.
- Organizer
  7th International Meeting on Metabotropic Glutamate Receptors
- Place of Presentation
  Taormina (Italy)
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] MPTP誘発酸化ストレスおよび中脳ドパミン神経変性にNa^+/Ca^<2+>交感系を介するERK活性化が関与する2011
- Author(s)
  梨子田哲明, 太田友樹, 吾郷由希夫, 川崎俊之, 高橋禎介, 田熊一敞、松田敏夫
- Organizer
  日本薬学会第131年会(地震)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] コルチコステロン慢性投与マウスでの代謝型グルタミン酸2/3受容体アンタゴニストの抗うつ様作用と前頭葉ドパミン神経系2011
- Author(s)
  矢野耕史、吾郷由希夫、荒木良太、平松直樹、田熊一敞、松田敏夫
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  ウィンクあいち（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 環境因子/ストレスホルモンによるうつ様行動の発現と代謝型グルタミン酸2/3受容体2011
- Author(s)
  吾郷由希夫、田熊一敞、松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光（石川県加賀市）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Antidepressant-like effect of a metabotropic glutamate 2/3 receptor antagonist2011
- Author(s)
  Yukio Ago, Shigeyuki Chaki, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  7th International Meeting on Metabotropic Glutamate Receptors
- Place of Presentation
  Atahotel Capotaormina （タオルミーナ, イタリア）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Involvement of prefrontal AMPA receptors in aggressive behavior and cognitive impairment of social isolation-reared mice.2011
- Author(s)
  Ryota Araki, Asuka Sasaga, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  The 41st annual meeting of the Society for Neuroscience (Neuroscience 2011)
- Place of Presentation
  Washigton DC (USA)
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] レボドパ誘発ジスキネジア形成過程における神経型一酸化窒素合成酵素の役割2011
- Author(s)
  叢雅娜, 高橋剛士, 吾郷由希夫, 田熊一敞、松田敏夫
- Organizer
  第84回日本薬理学会年会(地震)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] 選択的Na^+/Ca^<2+>交感系阻害薬SEA0400はMPTPによるERK活性化を介した参加ストレスを抑制しドパミン神経を保護する2011
- Author(s)
  太田友樹, 梨子田哲明, 吾郷由希夫, 川崎俊之, 高橋禎介, 田熊一敞、松田敏夫
- Organizer
  日本薬学会第131年会(地震)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] Role of brain metabotropic glutamate 2/3 receptors in social isolation-induced depressive behavior of mice.2011
- Author(s)
  Yukio Ago, Toshiyuki Kawasaki, Hirotaka Onoe, Kazuhiro Takuma, Toshio Matsuda.
- Organizer
  2nd congress of Asian College of Neuropsychopharmacology (AsCNP)
- Place of Presentation
  Seoul (Korea)
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] マウス間相互作用による長期隔離飼育マウス前頭前野の活性化とドパミン、セロトニン遊離の促進2011
- Author(s)
  荒木良太、吾郷由希夫、笹賀あすか、田熊一敞、松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光（石川県加賀市）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 環境因子/ストレスホルモンによるうつ様行動の発現と代謝型グルタミン酸2/3受容体2011
- Author(s)
  吾郷由希夫,田熊一敞,松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] グルココルチコイド長期負荷マウスにおける代謝型グルタミン酸2/3受容体拮抗薬の抗うつ様作用と前頭葉ドパミン神経機能の関与2011
- Author(s)
  矢野耕史,吾郷由希夫,荒木良太,平松直樹,田熊一敞,松田敏夫
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] Role of brain metabotropic glutamate 2/3 receptors in social isolation-induced depressive behavior of mice2011
- Author(s)
  Yukio Ago, Toshiyuki Kawasaki, Hirotaka Onoe, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  2nd congress of Asian College of Neuropsychopharmacology (AsCNP)
- Place of Presentation
  Grand Hilton Seoul Hotel （ソウル, 韓国）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] 神経型一酸化窒素合成酵素阻害剤7-nitroindazole は6-hydroxydopamine 神経障害ラットにおいてL-DOPA 誘発ジスキネジアの形成を抑制する2011
- Author(s)
  太田友樹, 田熊一敞, 高橋剛士, 吾郷由希夫, 松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Data Source
  KAKENHI-PROJECT-23390139
[Presentation] コルチコステロン慢性投与マウスでの代謝型グルタミン酸2/3受容体アンタゴニストの抗うつ様作用と前頭葉ドパミン神経系2011
- Author(s)
  矢野耕史,吾郷由希夫,荒木良太,平松直樹,田熊一敞,松田敏夫
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] グルココルチコイド長期負荷マウスにおける代謝型グルタミン酸2/3受容体拮抗薬の抗うつ様作用と前頭葉ドパミン神経機能の関与2011
- Author(s)
  矢野耕史、吾郷由希夫、荒木良太、平松直樹、田熊一敞、松田敏夫
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] マウス間相互作用による長期隔離飼育マウス前頭前野の活性化とドパミン、セロトニン遊離の促進2011
- Author(s)
  荒木良太,吾郷由希夫,笹賀あすか,田熊一敞,松田敏夫
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Data Source
  KAKENHI-PROJECT-23790599
[Presentation] ムスカリン受容体への作用の違いが長期隔離飼育誘発プレパルスインヒビション障害に対するガランタミンとドネペジルの作用の違いに関与する2011
- Author(s)
  香田健、吾郷由希夫、矢野耕史、深田亜沙子、梨子田哲明、太田友樹、田熊一敞、松田敏夫
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] ムスカリン受容体への作用の違いが長期隔離飼育誘発プレパルスインヒビション障害に対するガランタミンとドネペジルの作用の違いに関与する2011
- Author(s)
  香田健、吾郷由希夫、矢野耕史、深田亜沙子、梨子田哲明、太田友樹、田熊一敞、松田敏夫
- Organizer
  第84回日本薬理学会年会(変更→Journal of Pharmacological Sciences誌,Vol.115,Suppl.1)
- Place of Presentation
  (2011年3月22日予定から変更誌上開催(学会中止のため))
- Year and Date
  2011-02-15
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 海馬神経新生、栄養因子産生におけるpituitary adenylate cyclase-activating polypeptideの役割2010
- Author(s)
  吾郷由希夫、米山雅紀、荻田喜代一、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Alzheimer's disease drug galantamine, but not donepezil, improves social isolation rearing-induced deficits in prepulse inhibition via muscarinic acetylcholine receptors2010
- Author(s)
  Yukio Ago, Ken Koda, Koji Yano, Kazuhiro Takuma, Toshio Matsuda
- Organizer
  The 2010 XXVII Congress of the CINP (Collegium Internationale Neuro-Psychopharmacologicum)
- Place of Presentation
  香港(中国)
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 海馬神経新生、栄養因子産生におけるpituitary adenylate cyclase-activating polypeptideの役割2010
- Author(s)
  吾郷由希夫
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  宮城県,仙台国際センター
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21659063
[Presentation] 豊かな環境による海馬神経新生,栄養因子産生における神経ペプチドPACAPの役割2010
- Author(s)
  吾郷由希夫
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会合岡大会(Neuro2010)
- Place of Presentation
  兵庫県,神戸コンベンションセンター
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21659063
[Presentation] 長期隔離飼育マウス脳のムスカリンM1受容体機能低下2010
- Author(s)
  深田亜沙子、吾郷由希夫、香田健、矢野耕史、田熊一敞、松田敏夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Alzheimer's disease drug galantamine, but not donepezil, improves social isolation rearing-induced deficits in prepulse inhibition via muscarinic acetylcholine receptors2010
- Author(s)
  Yukio Ago、Ken Koda、Koji Yano、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 2010 XXVII Congress of the CINP (Collegium Internationale Neuro-Psychopharmacologicum)
- Place of Presentation
  Hong Kong (China)
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 一酸化窒素誘発ドパミン神経細胞内Ca^<2+>濃度上昇へのNa^+/Ca^<2+>交換系逆モードの関与2010
- Author(s)
  梨子田哲明、太田友樹、川崎俊之、吾郷由希夫、田熊一敞、松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] 豊かな環境による海馬神経新生、栄養因子産生における神経ペプチドPACAPの役割2010
- Author(s)
  吾郷由希夫、米山雅紀、荻田喜代一、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会合同大会(Neuro2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 発育期環境ストレス負荷による精神機能障害と創薬2010
- Author(s)
  吾郷由希夫、荒木良太、矢野耕史、田熊一敞、松田敏夫
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 栄養因子産生におけるpituitary adenylate cyclase-activating polypeptideの役割2010
- Author(s)
  吾郷由希夫、米山雅紀、荻田喜代一、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫、海馬神経新生
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] レボドパ誘発ジスキネジア形成過程における一酸化窒素の役割2010
- Author(s)
  高橋剛士, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] 隔離飼育誘発プレパルスインヒビション障害に対するガランタミン、ドネペジルの異なる作用の受容体機構2010
- Author(s)
  香田健、吾郷由希夫、矢野耕史、梨子田哲明、西村百恵、深田亜沙子、田熊一敞、松田敏夫
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] The Na^+/Ca^<2+> exchange inhibitor SEA0400 protects against dopaminergic neurodegeneration in a mouse model of Parkinson's disease.2010
- Author(s)
  梨子田哲明, 川崎俊之, 叢雅娜, 福田小夜子, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  The XXVII congress of the CINP (CINP2010)
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] Alzheimer's disease drug galantamine, but not donepezil, improves social isolation rearing-induced deficits in prepulse inhibition via muscarinic acetylcholine receptors2010
- Author(s)
  Yukio Ago
- Organizer
  The 2010 XXVII Congress of the CINP (Collegium Internationale Neuro-Psychopharmacologicum)
- Place of Presentation
  Hong Kong Convention and Exhibition Centre(香港)
- Year and Date
  2010-06-07
- Data Source
  KAKENHI-PROJECT-21659063
[Presentation] アルツハイマー病治療薬ガランタミンの感覚情報処理障害改善作用2010
- Author(s)
  吾郷由希夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府,摂南大学薬学部(招待講演)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21659063
[Presentation] Na^+/Ca^<2+>交換系-1はアストロサイトにおける一酸化窒素誘発細胞死に関与する2010
- Author(s)
  梨子田哲明, 北尾達哉, 井上由里子, 川崎俊之, 吾郷由希夫, 田熊一敞、松田敏夫
- Organizer
  Neuro 2010第33回日本神経科学大会,第53回日本神経化学会大会,第20回日本神経回路学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] 長期隔離飼育マウスの脳アセチルコリン神経系の機能解析2010
- Author(s)
  西村百恵、香田健、矢野耕史、吾郷由希夫、田熊一敞、松田敏夫
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 長期社会的隔離飼育による脳内ムスカリン性アセチルコリン受容体の機能低下2010
- Author(s)
  深田亜沙子、吾郷由希夫、香田健、矢野耕史、田熊一敞、松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 慢性拘束ストレス負荷マウスの情動行動変化における一酸化窒素の役割2010
- Author(s)
  虎谷祐伊, 梨子田哲明, 叢雅娜, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] 豊かな環境飼育によるPACAP遺伝子欠損マウス異常行動改善の持続性2010
- Author(s)
  山田さやか、片岡駿介、竹本光佑、吾郷由希夫、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] アルツハイマー病治療薬ガランタミンの感覚情報処理障害改善作用2010
- Author(s)
  吾郷由希夫、香田健、矢野耕史、田熊一敞、松田敏夫
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  枚方(招待講演)
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] グルココルチコイド長期負荷による中枢神経機能障害2010
- Author(s)
  吾郷由希夫、矢野耕史、荒木良太、田熊一敞、松田敏夫
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] MPTP誘発ドパミン神経障害に対するNa^+/Ca^<2+>交換系阻害薬SEA0400の保護作用2009
- Author(s)
  梨子田哲明, 川崎俊之、北尾達哉, 叢雅娜, 吾郷由希夫, 田熊一敞、松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2009
- Place of Presentation
  東京
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] Involvement of prefrontal dopaminergic system in antidepressant-like effect of the glucocorticoid receptor antagonist2009
- Author(s)
  Yukio Ago, 他5名
- Organizer
  The 22nd Biennial Meeting of the International Society for Neurochemistry/Asian Pacific Society for Neurochemistry Joint Meeting
- Place of Presentation
  釜山(韓国)
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 選択的Na^+/Ca^<2+>交換系阻害薬SEA0400のMPTP誘発ドパミン神経障害保護作用2009
- Author(s)
  梨子田哲明, 大槻健弥, 福田小夜子, 川崎俊之、北尾達哉, 吾郷由希夫, 田熊一敞、松田敏夫
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] Galantamine enhances cholinergic neurotransmission in vivo in mouse prefrontal cortex2009
- Author(s)
  Ken Koda、Koji Yano、Yukio Ago、Yuki Kita、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
- Place of Presentation
  Busan (Korea)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] アストロサイトの一酸化窒素誘発細胞死におけるNa^+/Ca^<2+>交換系を介するCa^<2+>流入の役割2009
- Author(s)
  井上由里子, 北尾達哉, 梨子田哲明, 川崎俊之, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] アルツハイマー病治療薬ガランタミンの感覚情報処理障害改善作用2009
- Author(s)
  吾郷由希夫、香田健、矢野耕史、田熊一敞、松田敏夫
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] アルツハイマー病治医療ガランタミンの感覚情報処理障害改善作用2009
- Author(s)
  吾郷由希夫, 他4名
- Organizer
  第59回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Effects of environmental factors during development on abnormal phenotypes in PACAP knock-out mice2009
- Author(s)
  Toshihiro Ishihama、Shunsuke Kataoka、Chika Manabe、Yukio Ago、Norihito Shintani、Hitoshi Hashimoto、Akemichi Baba、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 9th International Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  鹿児島
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] PACAP遺伝子欠損マウスの行動異常に対する発育環境の影響2009
- Author(s)
  真邉知佳、石濱壽紘、片岡駿介、吾郷由希夫、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第115回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 精神疾患と環境因子:長期隔離飼育マウスの行動薬理2009
- Author(s)
  吾郷由希夫, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390025
[Presentation] パーキンソン病モデルMPTP誘発ドパミン神経障害におけるNa^+/Ca^<2+>交換系の関与2009
- Author(s)
  梨子田哲明, 川崎俊之, 大槻健弥, 北尾達哉, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  シンポジウム「精神・神経・筋疾患のトランスレーショナルリサーチ」第52回日本神経化学会大会
- Place of Presentation
  伊香保温泉
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] PACAP遺伝子欠損マウス表現型の発育期環境因子依存性2009
- Author(s)
  石濱壽紘、片岡駿介、真邉知佳、吾郷由希夫、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第6回GPCR研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Involvement of prefrontal dopaminergic system in antidepressant-like effect of the glucocorticoid receptor antagonist2009
- Author(s)
  Yukio Ago、Koji Yano、Ken Koda、Yuki Kita、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
- Place of Presentation
  Busan (Korea)
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] ガランタミンの長期隔離飼育誘発プレパルスインヒビション障害改善作用:ムスカリン性アセチルコリンM_1受容体の関与2009
- Author(s)
  吾郷由希夫、香田健、矢野耕史、梨子田哲明、田熊一敞、松田敏夫
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
- Place of Presentation
  京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] ガランタミンの感覚情報処理障害改善作用におけるムスカリンM1受容体の関与2009
- Author(s)
  矢野耕史、香田健、西村百恵、梨子田哲明、吾郷由希夫、田熊一敞、松田敏夫
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2009
- Place of Presentation
  東京
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Galantamine, but not donepezil, improves isolation rearing-induced deficits in prepulse inhibition : Implication of M_1 muscarinic acetylcholine receptors2009
- Author(s)
  Yukio Ago、Ken Koda、Koji Yano、Tetsuaki Nashida、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 1st Meeting of the Asian College of Neuropsycho- pharmacology (AsCNP)
- Place of Presentation
  京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] ガランタミンのムスカリン受容体活性化を介したアポモルヒネ誘発プレパルスインヒビション障害抑制作用2009
- Author(s)
  矢野耕史、香田健、吾郷由希夫、西村百恵、田熊一敞、松田敏夫
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Environmental factors during development regulate the behavioral phenotypes of PACAP knockout mice2009
- Author(s)
  Toshihiro Ishihama、Shunsuke Kataoka、Chika Manabe、Yukio Ago、Norihito Shintani、Hitoshi Hashimoto、Akemichi Baba、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
- Place of Presentation
  Busan (Korea)
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] ガランタミンはドパミンD1受容体の活性化とアセチルコリンエステラーゼ阻害作用によりマウス大脳皮質において細胞外アセチルコリン量を増加させる2009
- Author(s)
  矢野耕史、香田健、吾郷由希夫、喜多祐紀、田熊一敞、松田敏夫
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] 幼若期環境強化のPACAP遺伝子欠損マウス異常行動に与える影響2009
- Author(s)
  片岡駿介、石濱壽紘、真邉知佳、吾郷由希夫、新谷紀人、橋本均、馬場明道、田熊一敞、松田敏夫
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同年会
- Place of Presentation
  京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Galantamine, but not donepezil, improves isolation rearing-induced deficits in prepulse inhibition : Implication of M_1 muscarinic acetylcholine receptors2009
- Author(s)
  Yukio Ago, 他5名
- Organizer
  The 1st Meeting of the Asian College of Neuropsychopharmacology (AsCNP)
- Place of Presentation
  京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Early environmental enrichment improves some behavioral abnormalities in PACAP-KO mice2009
- Author(s)
  Shunsuke Kataoka、Toshihiro Ishihama、Chika Manabe、Yukio Ago、Norihito Shintani、Hitoshi Hashimoto、Akemichi Baba、Kazuhiro Takuma、Toshio Matsuda
- Organizer
  The 1st Meeting of the Asian College of Neuropsycho- pharmacology (AsCNP)
- Place of Presentation
  京都
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21790521
[Presentation] Involvement of Na^+/Ca^<2+> exchanger in nitric-oxide-induced cytotoxicity in SH-SY5Y cells.2008
- Author(s)
  梨子田哲明, 川崎俊之, 北尾達哉, 福田小夜子, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第51回日本神経化学会大会, The 2nd Asia Pacific Congress ofBiological Psychiatry,第30回日本生物学的精神医学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] アストロサイトのNO誘発^<45>Ca^<2+>流入へのNa^+-Ca^<2+>交換系の関与2008
- Author(s)
  北尾達哉, 井上由里子, 梨子田哲明, 川崎俊之, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第13回グリア研究会
- Place of Presentation
  東京
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] Nitric oxide-induced astrocyte apoptosis and its protection by the radical scavenger edaravone.2008
- Author(s)
  北尾達哉, 川崎俊之, 梨子田哲明, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington D.C., USA
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] SH-SY5Y細胞における一酸化窒素によるNa^+/Ca^<2+>交換系を介するCa^<2+>流入2008
- Author(s)
  福田小夜子, 梨子田哲明, 川崎俊之、北尾達哉, 吾郷由希夫, 田熊一敞、松田敏夫
- Organizer
  第114回日本薬理学会近畿部会
- Place of Presentation
  神戸
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] PACAP遺伝子改変マウスの異常行動と環境因子2008
- Author(s)
  吾郷由希夫
- Organizer
  生体機能と創薬シンポジウム2008
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18390025
[Presentation] 選択的Na^+/Ca^<2+>交換系阻害薬SEA0400のパーキンソン病モデルマウスでの有効性2008
- Author(s)
  梨子田哲明, 福田小夜子, 川崎俊之, 北尾達哉, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  生体機能と創薬シンポジウム2008生命システムにおける情報ネットワークの重要性を解く
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] SH-SY5Y 細胞における一酸化窒素誘発細胞死へのNa^+/Ca^<2+>交換系の関与2008
- Author(s)
  梨子田哲明, 川崎俊之, 北尾達哉, 福田小夜子, 吾郷由希夫, 松田敏夫
- Organizer
  第31回日本神経科学大会(Neuroscience2008)
- Data Source
  KAKENHI-PROJECT-20390159
[Presentation] マウスメタンフェタミン誘発行動感作への前頭葉セロトニン神経系の関与2007
- Author(s)
  吾郷由希夫
- Organizer
  第37回日本神経精神薬理学会・第29回生物学的精神医学
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18790365
[Presentation] アルツハイマー病治療薬ガランタミンのプレパルスインヒビション障害改善作2007
- Author(s)
  吾郷由希夫
- Organizer
  第35回薬物活性シンポジウム
- Place of Presentation
  広島県歯科医師会館
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-18790365
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応のADHD治療薬による抑制
- Author(s)
  長谷部茂, 西山早紀, 岡智史, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Social crowding in the night-time reduces an anxiety-like behavior and increases social interaction in adolescent mice
- Author(s)
  Ota Y, Ago Y, Tanaka T, Kitamoto M, Imoto E, Takuma K, Matsuda T
- Organizer
  The 8th Soul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
- Place of Presentation
  大阪大学（吹田）
- Year and Date
  2014-06-10 – 2014-06-11
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター誘発多動反応に対する抗うつ薬の作用
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 中森大貴, 田熊一敞, 松田敏夫
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Encounter stimulation-induced hyperactivity of social isolation-reared mice is attenuated by antidepressants
- Author(s)
  Hasebe S, Ago Y, Nishiyama S, Oka S, Nakamori D, Takuma K, Matsuda T
- Organizer
  The 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014)
- Place of Presentation
  Walter E. Washington Convention Center (Washington, D.C., USA)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] Rearing in overcrowded conditions in the night-time induces anxiolytic-like effects in adolescent mice
- Author(s)
  Tanaka T, Ago Y, Ota Y, Imoto E, Kitamoto M, Takuma K, Matsuda T
- Organizer
  The 44th Annual Meeting of the Society for Neuroscience (Neuroscience 2014)
- Place of Presentation
  Walter E. Washington Convention Center (Washington, D.C., USA)
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 精神刺激薬反復投与マウスのエンカウンター刺激による多動
- Author(s)
  田中辰典, 吾郷由希夫, 井本絵実奈, 田熊一敞, 松田敏夫
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良県文化会館（奈良）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 夜間拘束ストレスの抗不安様作用
- Author(s)
  田中辰典, 太田友樹, 長谷部茂, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 長期隔離飼育マウスのエンカウンター異常反応の神経薬理学的解析
- Author(s)
  長谷部茂, 吾郷由希夫, 西山早紀, 岡智史, 田熊一敞, 松田敏夫
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫医療大学（神戸）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] マウス間相互作用を基盤とした新規意欲評価系
- Author(s)
  吾郷由希夫, 長谷部茂, 西山早紀, 岡智史, 尾中勇祐, 田熊一敞, 松田敏夫
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460099
[Presentation] 夜間拘束ストレスはマウスの不安様行動を減少させる
- Author(s)
  太田友樹, 田中辰典, 吾郷由希夫, 田熊一敞, 松田敏夫
- Organizer
  第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良県文化会館（奈良）
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-25460099

1. TAKUMA Kazuhiro (90289025)

# of Collaborated Projects: 5 results

# of Collaborated Products: 63 results
2. MATSUDA Toshio (00107103)

# of Collaborated Projects: 5 results

# of Collaborated Products: 77 results
3. HASHIMOTO Hitoshi (30240849)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
4. SHINTANI Norihito (10335367)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Irifune Masahiro (10176521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 中澤敬信 (00447335)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
7. BABA Akemichi (70107100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. HASHIMOTO Ryota (10370983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KUNUGI Hiroshi (40234471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOHYAMA Masaya (40028593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKEDA Masatoshi (00179649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Yoshioka Yasuo (00392308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Miyata Atsuro (60183969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 長谷部茂 (30754725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. 近藤昌夫 (50309697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 鈴木亮 (90384784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 佐藤慎太郎 (80447333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
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# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 神戸悠輝 (60549913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 高崎一朗 (00397176)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
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# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. 森岡徳光 (20346505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. 應原一久 (80550425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. 古武弥一郎 (20335649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. 大黒亜美 (20634497)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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33. 森田克也 (10116684)

# of Collaborated Projects: 1 results

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34. 土肥敏博 (00034182)

# of Collaborated Projects: 1 results

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35. 酒井規雄 (70263407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. 光畑智恵子 (10335664)

# of Collaborated Projects: 1 results

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37. 宮崎博子 (40461355)

# of Collaborated Projects: 1 results

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38. 田中正子 (60515807)

# of Collaborated Projects: 1 results

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39. 篠原幸恵 (70845388)

# of Collaborated Projects: 1 results

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40. 窪田志穂 (60634409)

# of Collaborated Projects: 1 results

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41. 向下寿子 (00634461)

# of Collaborated Projects: 1 results

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42. 岡田芳幸 (70566661)

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 1 results

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44. MAEDA Yuko

# of Collaborated Projects: 1 results

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# of Collaborated Projects: 0 results

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# of Collaborated Projects: 0 results

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48. 兼松隆

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# of Collaborated Projects: 0 results

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50. 都英次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
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# of Collaborated Projects: 0 results

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52. 石本憲司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 山脇洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 宮山篤郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 岡村孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AGO Yukio 吾郷 由希夫

Ago Yukio 吾郷 由希夫

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Elucidation of the pathological mechanism of treatment-refractory schizophrenia and drug discovery research focusing on abnormalities in peptide signaling during brain developmentPrincipal Investigator

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Identification of novel factors mediating the effects of environmental enrichment in the absence of voluntary exercise on psychiatric disordersPrincipal Investigator

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Development of the integrated therapeutic strategy aiming toward drug discovery and pharmacotherapy for treatment-resistant schizophreniaPrincipal Investigator

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Drug discovery research targeting the novel regulation of prefrontal dopaminergic system by the functional interaction between the sigma1 and serotonin1A receptorsPrincipal Investigator

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Drug discovery research targeting brain neurochemical signals responsible for induction of abnormal behaviors in mouse models of psychiatric disordersPrincipal Investigator

AGO Yukio 吾郷由希夫

Ago Yukio 吾郷由希夫