KONDOH Masuo 近藤昌夫

Researcher Number	50309697
Other IDs
External Links
Affiliation *help	2018 : 大阪大学, 薬学研究科, 教授 2017 : 大阪大学, 薬学研究科, 招へい准教授 2015 – 2016 : 大阪大学, 大学院薬学研究科, 准教授 2011 – 2014 : 大阪大学, 薬学研究科(研究院), 准教授 2011 : 大阪大学, 大学院・薬学研究科, 准教授 … More
Review Section/Research Field	Principal Investigator Medical pharmacy / Biological pharmacy / Environmental pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Medical pharmacy / Environmental pharmacy / Structural biochemistry
Keywords	Principal Investigator claudin / tight junction / 非侵襲性投与 / タイトジャンクション / Claudin / アデノウイルス / 長鎖RNA / RNA pol I系 / zinc / C型肝炎 … More Except Principal Investigator タイトジャンクション / trophoblast cell / 生体機能利用 / gene delivery system / メタロチオネイン / fiber-modified adenovirus vector / integrin / 生体膜透過バリアー機能 / 活性酸素 / transgene expression / 生理活性 / 薬理学 / coxsackievirus and adenovirus receptor / 薬物透過機構 / マイクロアレイ解析 / CAR / 生体膜透過制御機構 / metallothionein / 胎盤 / 膜タンパク質 / ミトコンドリア / アデノウイルスベクター / キャプシガーリン / GRP78 / アデノウィルスベクター / 消化管上皮細胞層 / RNA干渉 / transgene oxpression / trohoblast cell / 生理活学 / gene deliverv system / 遺伝子導入 / 薬物透過制御法 / 遺伝子発現 / adenovirus vector / 胎盤関門 / 呼吸阻害剤 / placental barrier / 肥満 / endoplasmic reticulum / RNA interference / 薬剤反応性 / 生体膜透過性 / 白色脂肪組織 / dinitrophenol / Bip / 吸収促進法 / 遺伝子 / placenta / ヘパラン硫酸 / 国際情報交換 / pharmacology / Ｘ線結晶構造解析 / トロホブラスト細胞 / バイオ医薬品DDSの基礎研究 / スーパーオキシドジスムターゼ / ジニトロフェノール / ツニカマイシン / 薬物吸収促進作用 / タイトジャンクション構成分子 / drug permeation / レプチン / 薬学 / 生体膜透過制御 / 2,4-ジニトロフェノール / 遺伝子導入用アデノウイルスベクター / 高分子薬物透過促進 / mitochondria / 生体膜バリアー機構 / reactive oxygen species / 小胞体ストレス / 薬物透過 / coxsackievirus and adenovirus recepter / 遺伝子解析 / 生理学 / 生体膜透過促進物質 / metallothioenein / tunicamycin / 線維芽細胞 Less

血液脳関門シールド制御による脳内薬物送達技術の開発への挑戦Principal InvestigatorOngoing
- Principal Investigator
  
  近藤昌夫
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Studies on molecular mechanism of paracellular pathway
- Principal Investigator
  
  Aoyama Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Strategic approach based on molecular mechanism for modulation of barrier function of tight junction to enhance delivery of new biopharmaceuticals
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
Claudin-1 as a target for modulation of epidermal barriersPrincipal Investigator
- Principal Investigator
  
  KONDOH Masuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
Development ofan assay system for hepatitis C virus in micePrincipal Investigator
- Principal Investigator
  
  KONDOH Masuo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
Studies of barrier function of tight junction in epithelial celllayers and strategic development of novel methods for drug permeation enhancement in cells
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
Development of non-invasive drug delivery system using claudin modulatorPrincipal Investigator
- Principal Investigator
  
  KONDOH Masuo
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
RNAポリメラーゼI発現系を利用したC型肝炎ウイルス増幅系の開発Principal Investigator
- Principal Investigator
  
  近藤昌夫
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University
A Novel Strategy for Enhancement of Permeation and Absorption of Drugs by Modulation of Proteins Constructed Barrier Function in Biomembrane
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
Claudin modulatorを利用した新規薬物送達方法の構築Principal Investigator
- Principal Investigator
  
  近藤昌夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University
Studies on Drug Permeation in Placental Barrier by RNA Interference
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
タイトジャンクション構成分子Claudinを標的とした新規吸収促進戦略の確立Principal Investigator
- Principal Investigator
  
  近藤昌夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
Development of Gene Transfer Systems into Placental Cells for Studies of Drug Transport Mechanism in Blood-Placenta Barrier
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Showa Pharmaceutical University
Role of metallothionein against toxicity of reactive oxygen species induced mitochondria
- Principal Investigator
  
  SATO Masao
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Tokushima Bunri University
小胞体ストレスに対するメタロチオネインの誘導および防御作用
- Principal Investigator
  
  SATO Masao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  Tokushima Bunri University
メタロチオネインのストレス系細胞内シグナル伝達調節機構Principal Investigator
- Principal Investigator
  
  近藤昌夫
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Tokushima Bunri University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Monoclonal antibodies against extracellular domains of claudin-1 block hepatitis C virus infection in a mouse model.2015
- Author(s)
  Masayoshi Fukasawa, Shotaro Nagase, Yoshitaka Shirasago, Manami Iida, Mayo Yamashita, Kohki Endo, Kiyohito Yagi, Tetsuro Suzuki, Takaji Wakita, Kentaro Hanada, Hiroki Kuniyasu, Masuo Kondoh
- Journal Title
  
  Journal of Virology
  
  Volume : 89 Pages : 4866-4879
- DOI
  10.1128/JVI.03676-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390042, KAKENHI-PROJECT-25670177, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-23590104, KAKENHI-PROJECT-26670224, KAKENHI-PROJECT-25293134
[Journal Article] Discovery of anti-claudin-1 antibodies as candidate therapeutics against hepatitis C virus.2015
- Author(s)
  Mayo Yamashita, Manami Iida, Minoru Tada, Yohitaka Shirasago, Masayoshi Fukasawa, Shotaro Nagase, Akihiro Watari, Akiko Ishii-Watabe, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume : 353 Pages : 112-118
- DOI
  10.1124/jpet.114.217653
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390042, KAKENHI-PROJECT-26860078
[Journal Article] Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers2015
- Author(s)
  Akihiro Watari, Maki Hasegawa, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Eur J Pharm Biopharm.
  
  Volume : 89 Pages : 232-238
- DOI
  10.1016/j.ejpb.2014.12.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390042, KAKENHI-PROJECT-26860078
[Journal Article] The new era of epithelium-targeted drug development2014
- Author(s)
  Yoshimi Shimizu, Shotaro Nagase, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Yakugakuzasshi
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] The cutting edge of epithelium-targeted drug development2014
- Author(s)
  Masuo Kondoh, Jun Kunisawa
- Journal Title
  
  Yakugakuzasshi
  
  Volume : in press
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Development of an anti-claudin-3 and -4 bispecific monoclonal antibody for cancer diagnosis and therapy.2014
- Author(s)
  Xiangru Li, Manami Iida, Minoru Tada, Akihiro Watari, Yumi Kawahigashi, Yuka Kimura, Taku Yamashita, Akiko Ishii-Watabe, Tadayuki Uno, Masayoshi Fukasawa, Hiroki Kuniyasu, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume : 351 Pages : 206-213
- DOI
  10.1124/jpet.114.216911
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390042, KAKENHI-PROJECT-25670177, KAKENHI-PROJECT-26860078
[Journal Article] Tissue distribution and safety evaluation of a claudin-targeting 4 molecule, the C-terminal fragment of Clostridium perfringens enterotoxin.2014
- Author(s)
  Xiangru Li, Rie Saeki, Akihiro Watari, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Eur. J. Pharm. Sci.
  
  Volume : 52 Pages : 132-137
- DOI
  10.1016/j.ejps.2013.10.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390042, KAKENHI-PROJECT-24790155
[Journal Article] Tissue distribution and safety evaluation of a claudin-targeting molecule, the C-terminal fragment of Clostridium perfringens enterotoxin2014
- Author(s)
  Xiangru Li, Rie Saeki, Akihiro Watari, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Eur J Pharm Sci
  
  Volume : 52 Pages : 132-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Claudinを標的とした創薬研究の最前線2013
- Author(s)
  飯田愛未、八木清仁、近藤昌夫
- Journal Title
  
  膜
  
  Volume : 38 Pages : 174-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] A baculoviral display system to assay viral entry2013
- Author(s)
  Manami Iida, Takeshi Yoshida, Akihiro Watari, Kiyohito Yagi, Takao Hamakubo, Masuo Kondoh
- Journal Title
  
  Biol Pharm Bull
  
  Volume : 36 Pages : 1867-1869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Percolation Analysis in Electrical Conductivity of Madin-Darby Canine Kidney and Caco-2 Cells by Permeation-Enhancing Agents2013
- Author(s)
  Washiyama M, Koizumi N, Fujii M, Kondoh M, Yagi K, Watanabe Y.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume : 36 Pages : 384-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460222
[Journal Article] Recent advances in claudin-targeting technology2013
- Author(s)
  Shotaro Nagase, Ryo Doyama, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Biol Pharm Bull
  
  Volume : 36 Pages : 708-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Percolation Analysis in Electrical Conductivity of MDCK and Caco-2 Cells Permeat ion-Enhanc ing Agents2013
- Author(s)
  Makiko Washiyama, Naoya Koizumi, Makiko Fujii, Masuo Kondoh, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biol Pharm Bull
  
  Volume : 36 Pages : 384-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Development of an adenovirus vector containing a hepatitis C virus expression cassette and its application2013
- Author(s)
  Takeshi Yoshida, Masuo Kondoh, Hiroyuki Mizuguchi, Kiyohito Yagi
- Journal Title
  
  Yakugakuzasshi
  
  Volume : 133 Pages : 305-311
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] New approaches to drug discovery research and medical treatment using viruses-Viruses are valuable materials-2013
- Author(s)
  Fuminori Sakurai, Masuo Kondoh
- Journal Title
  
  Yakugakuzasshi
  
  Volume : 133 Pages : 289-289
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Recent advances ln claudin-target ing technology2013
- Author(s)
  Shotaro Nagase, Ryo Doyama, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Biol Pharm Bull
  
  Volume : 36 Pages : 708-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] A simple reporter assay for screening claudin-4 modulators2012
- Author(s)
  Akihiro Watari, Kiyohito Yagi, Masuo Kondoh
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 426 Pages : 454-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Spiral progression in the development of absorption enhancers based on the biology of tight junctions2012
- Author(s)
  Kondoh, M.; Takahashi, A.; Yagi, K
- Journal Title
  
  Adv Drug Deliv Rev
  
  Volume : 64 Pages : 515-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice2012
- Author(s)
  Suzuki, H.; Kondoh, M.; Kakutani, H.; Yamane, S.; Uchida, H.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biomaterials
  
  Volume : 33 Pages : 317-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a2012
- Author(s)
  Fuminori Sakurai, Norihisa Furukawa, Maiko Higuchi, Sayuri Okamoto, Kaori Ono, Takeshi Yoshida, Masuo Kondoh, Kiyohito Yagi, Naoya Sakamoto, Kazufumi Katayama, Hiroyuki Mizuguchi
- Journal Title
  
  Virus Res
  
  Volume : 165 Pages : 214-218
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] New approaches to drug discovery research and medical treatment using viruses-Viruses are valuable materials2012
- Author(s)
  Fuminori Sakurai, Masuo Kondoh
- Journal Title
  
  Yakugakuzasshi
  
  Volume : 133 Pages : 289-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a2012
- Author(s)
  Sakurai F., Furukawa N., Higuchi M., Okamoto S., Ono K., Yoshida T., Kondoh M., Yagi K., Sakamoto N., Katayama K., Mizuguchi H
- Journal Title
  
  Virus Res
  
  Volume : 165 Pages : 214-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Oil-in-water emulsion lot ion providing controlled release using 2-methacryloyloxyethyl phosphorylcholine n-butyl methacrylate copolymer as cmulsifier2012
- Author(s)
  Akiko Ishikawa, Makiko Fujii, Kumi Mori moto, Naoya Koizumi, Masuo Kondoh, Yoshitoru Watanabe
- Journal Title
  
  Pharm Sci
  
  Volume : 2 Pages : 16-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Comparison of mucosal absorption-enhancing activity between a claudin-3/ -binder and a broadly specific claudirt binder2012
- Author(s)
  Koji Matsuhisa, Masuo Kondoh, Hidehiko Suzuki, Kiyohito Yagi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 423 Pages : 229-233
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Creatioll and biochemical analysis of a broad-specific claudin binder2012
- Author(s)
  Azusa Takahashi, Yumiko Saito, Masuo Kondoh, Kyohei Matsushi ta, Susanne M. Krug, Hidehiko Suzuki, Hirofumi Tsujino, Xiangru Li, Hiroshi Aoyama, Koji Matsuhisa, Tadayuki Uno, Michael Fromm, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  Biomatcrials
  
  Volume : 33 Pages : 3464-3474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice2012
- Author(s)
  Hidehiko Suzuki, Masuo Kondoh, Hideki Kakutani, Seiji Yamane, Hiroshi Uchida, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  Biomatcrials
  
  Volume : 33 Pages : 317-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Pathological changes in tight junctions and potential applicat ions into therapi e2012
- Author(s)
  Azusa Takahashi, Masuo Kondoh, Hidehiko Suzuki, Akihiro Watari, Kiyohito Yagi
- Journal Title
  
  Drug Discov Today
  
  Volume : 17 Pages : 727-732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Spiral progression in the development of absorption enhancers based on the biology of tight junctions2012
- Author(s)
  Masuo Kondoh, Azusa Takahashi, Kiyohito Yagi
- Journal Title
  
  Adv Drug Deliv Rev
  
  Volume : 64 Pages : 515-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Proof of concept for claudin-target.ed drug development2012
- Author(s)
  Hidehiko Suzuki, Masuo Kondoh, Azusa Takahashi, Kiyohito Yagi
- Journal Title
  
  Ann NY Acad Sci
  
  Volume : 1258 Pages : 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390042
[Journal Article] Creation and biochemical analysis of a broad-specific claudin binder.2012
- Author(s)
  Takahashi, A.; Saito, Y.; Kondoh, M.; Matsushita, K.; Krug, S. M.; Suzuki, H.; Tsujino, H.; Li, X.; Aoyama, H.; Matsuhisa, K.; Uno, T.; Fromm, M.; Tamakubo, T.; Yagi, K.
- Journal Title
  
  Biomaterials
  
  Volume : 33 Pages : 3464-3474
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Spiral progression in the development of absorption enhancers based on the biology of tight junctions.2012
- Author(s)
  Kondoh, M.; Takahashi, A.; Yagi, K.
- Journal Title
  
  Adv Drug Deliv Rev
  
  Volume : 64 Pages : 515-522
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] The application of an alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin as a mucosal vaccine in mice.2012
- Author(s)
  Suzuki, H.; Kondoh, M.; Kakutani, H.; Yamane, S.; Uchida, H.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biomaterials
  
  Volume : 33 Pages : 317-324
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Pathological changes in tight junctions and potential application into therapies.2012
- Author(s)
  Takahashi, A.; Kondoh, M.; Suzuki, H.; Watari, A.; Yagi, K.
- Journal Title
  
  Drug Discov Today
  
  Volume : 17 Pages : 727-732
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Mutated C-terminal fragments of Clostridium perfringens enterotoxin have increased affinity to claudin-4 and reversibly modulate tight junctions in vitro.2011
- Author(s)
  Takahashi, A.; Kondoh, M.; Uchida, H.; Kakamu, Y.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 410 Pages : 466-470
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A Non-invasive Drug Delivery System Using Claudin Binder2011
- Author(s)
  Takahashi, A.; Kondoh, M.; Yagi, K
- Journal Title
  
  Yakugaku Zasshi
  
  Volume : 131 Pages : 1583-1587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Mutated C-terminal fragments of Clostridium perfringens enterotoxin have increased affinity to claudin-4 and reversibly modulate tight junctions in vitro2011
- Author(s)
  Takahashi, A.; Kondoh, M.; Uchida, H.; Kakamu, Y.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 410 Pages : 466-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Claudin as a target for drug development2011
- Author(s)
  Takahashi, A.; Kondoh, M.; Yagi, K.
- Journal Title
  
  Curr Med Chem
  
  Volume : 18 Pages : 1861-1865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A novel screening system for claudin binder using baculoviral display2011
- Author(s)
  Kakutani, H.; Takahashi, A.; Kondoh, M.; Saito, Y.; Yamaura, T.; Sakihama, T.; Hamakubo, T.; Yagi, K
- Journal Title
  
  PLoS One
  
  Volume : 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Promising targets for anti-hepatitis C virus agents2011
- Author(s)
  Takeshi Yoshida, Masuo Kondoh, Kiyohito Yagi
- Journal Title
  
  Curr Med Chem
  
  Volume : 18 Pages : 1239-1244
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Adenovirus vector-mediated assay system for Hepati2011
- Author(s)
  T. Yoshida, M. Kondoh, M., et al.
- Journal Title
  
  Nucleic Acid Res
  
  Volume : 39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Adenovirus vector-mediated assay system for Hepatitis C virus replication2011
- Author(s)
  Takeshi Yoshida, Masuo Kondoh, Manabu Ojima, Hiroyuki Mizuguchi, Yoshiaki Yamagishi, Naoya Sakamoto, Kiyohito Yagi
- Journal Title
  
  Nucleic Acid Res
  
  Volume : 39
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection2011
- Author(s)
  Takeshi Yoshida, Kazuo Takayama, Masuo Kondoh, Fuminori Sakurai, Hideki Tani, Naoya Sakamoto, Yoshiharu Matsuura, Hiroyuki Mizuguchi, Kiyohito Yagi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 416 Pages : 119-124
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] A novel screening system for claudin binder using baculoviral display2011
- Author(s)
  Hideki Kakutani, Azusa Takahashi, Masuo Kondoh, Yumiko Saito, Toshiaki Yamaura, Toshiko Sakihama, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  PLos One
  
  Volume : 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A novel screening system for claudin binder using baculoviral display.2011
- Author(s)
  Kakutani, H.; Takahashi, A.; Kondoh, M.; Saito, Y.; Yamaura, T.; Sakihama, T.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  PLoS One
  
  Volume : 6
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Claudin as a target for drug development.2011
- Author(s)
  Takahashi, A.; Kondoh, M.; Yagi, K.
- Journal Title
  
  Curr Med Chem
  
  Volume : 18 Pages : 1861-1865
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A toxicological evaluation of a claudin modulator, Oterminal fragment of Clostridium perfringens enterotoxin, in mice2011
- Author(s)
  Hidehiko Suzuki, Masuo Kondoh, Xangru Li, Azusa Takahashi, Kohji Matsuhisa, Kyohei Matsushita, Yohei Kakamu, Seiji Yamane, Miki Kodaka, Katsuhiro Isoda, Kiyohito Yagi
- Journal Title
  
  Pharmazie
  
  Volume : 66 Pages : 543-546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Use of human hepatocyte-like cells derived from in2011
- Author(s)
  T.i Yoshida, K. Takayama, M. Kondoh, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 416 Pages : 119-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659039
[Journal Article] タイトジャンクションを標的とした創薬研究のらせん的発展2011
- Author(s)
  近藤昌夫、八木清仁
- Journal Title
  
  ファルマシア
  
  Volume : 47 Pages : 1145-1148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin2010
- Author(s)
  H.Kakutani, M.Kondoh, R.Saeki, M.Fujii, Y.Watanabe, H.Muzuguchi, K.Yagi
- Journal Title
  
  Eur.J.Pharm.Biopharm. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590178
[Journal Article] Mucosal vaccination using claudin-4-targeting.2010
- Author(s)
  Kakutani, H.; Kondoh, M.; Fukasaka, M.; Suzuki, H.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biomaterials
  
  Volume : 31 Pages : 5463-5471
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin2010
- Author(s)
  H. Kakutani, M. Kondoh, R. Saeki, M. Fujii, Y. Watanabe, H. Muzuguchi, K. Yagi
- Journal Title
  
  Eur. J. Pharm. Biopharm
  
  Volume : 75 Pages : 213-217
- DOI
  10.1016/j.ejpb.2010.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590178
[Journal Article] A claudin-4 modulator enhances the mucosal absorption of a biologically active peptide2010
- Author(s)
  Hiroshi Uchida, Masuo Kondoh, Takeshi, Hanada, Azusa Takahashi, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  Biochem.Pharmacol. 79
  
  Pages : 1437-1444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A claudin-targeting molecule as an inhibitor of tumor metastasis.2010
- Author(s)
  Saeki, R.; Kondoh, M.; Kakutani, H.; Matsuhisa, K.; Takahashi, A.; Suzuki, H.; Kakamu, Y.; Watari, A.; Yagi, K.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume : 334 Pages : 576-582
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A claudin-4 modulator enhances the mucosal absorption of a biologically active peptide.2010
- Author(s)
  Uchida, H.; Kondoh, M.; Hanada, T.; Takahashi, A.; Hamakubo, T.; Yagi, K.
- Journal Title
  
  Biochem Pharmacol
  
  Volume : 79 Pages : 1437-1444
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A claudin-targeting molecule as an inhibitor of tumor metastasis2010
- Author(s)
  Rie Saeki, Masuo Kondoh, Hideki Kakutani, Kohji Matsuhisa, Azusa Takahashi, Hidehiko Suzuki, Yohei Kakamu, Akihiro Watari, Kiyohito Yagi
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume : 334 Pages : 576-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] The safety of a mucosal vaccine using the C-terminal fragment of Clostridium perfringens enterotoxin2010
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Masuo Kondoh, Akihiro Watari, Kiyohito Yagi
- Journal Title
  
  Pharmazie
  
  Volume : 10 Pages : 766-769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Mucosal vaccination using claudin-4 targeting2010
- Author(s)
  Hideki Kakutani, Masuo Kondoh, Masahiro Fukasaka, Hidehiko Suzuki, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  Biomaterials
  
  Volume : 31 Pages : 5463-5471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin2010
- Author(s)
  Hideki Kakutani, Masuo Kondoh, Rie Saeki, Makiko Fujii, Yoshiteru Watanabe, Hiroyuki Mizuguchi, Kiyohito Yagi
- Journal Title
  
  Eur J Pharm Biopharm
  
  Volume : 75 Pages : 213-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Potency of claudin-targeting as antitumor therapy2010
- Author(s)
  Rie Saeki, Masuo Kondoh, Hiroshi Uchida, Kiyohito Yagi
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume : 2 Pages : 47-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] A claudin-4 modulator enhances the mucosal absorption of a bioloeically active peptide2010
- Author(s)
  Hiroshi Uchida, Masuo Kondoh, Takeshi Hanada, Azusa Takahashi, Takao Hamakubo, Kiyohito Yagi
- Journal Title
  
  Biochem Pharmacol
  
  Volume : 79 Pages : 1437-1444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Prevention of hepatic ischemia-reperfusion in jury by pre-administration of catalase-expressing adenovirus vectors2010
- Author(s)
  Masahiro Ushitora, Fuminori Sakurai, Tomoko Yamaguchi, Shin-ichiro Nakamura, Masuo Kondoh, Kiyohito Yagi, Kenji Kawabata, Hiroyuki Mizuguchi
- Journal Title
  
  J. Control. Rel. 142
  
  Pages : 431-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659012
[Journal Article] A novel tumor-targeted therapy using a claudin-4-targeting molecule2009
- Author(s)
  Rie Saeki, Masuo Kondoh, Hideki Kakutani, Shin-ichi Tsunoda, Yasuhiro Mochizuki, Takao Hamakubo, Yasuo Tsutsumi, Yasuhiko Horiguchi, Kivohito Yagi
- Journal Title
  
  Mol.Pharmacol. 76
  
  Pages : 918-926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Tight junction modulators and drug delivery2009
- Author(s)
  Koji Matsuhisa, Masuo Kondoh, Azusa Takahashi, Kiyohito Yagi
- Journal Title
  
  Expert Opin.Drug Deliv. 6
  
  Pages : 509-515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Light junction modulators and drug delivery2009
- Author(s)
  近藤昌夫、高橋梓、佐伯理恵、八木清仁
- Journal Title
  
  Drug Delivery System 24
  
  Pages : 532-537
- Data Source
  KAKENHI-PROJECT-21689006
[Journal Article] Targeting tight junction proteins-significance for drug development2008
- Author(s)
  Masuo Kondoh, Takeshi Yoshida, Hideki Kakutani, Kiyohito Yagi
- Journal Title
  
  Drug Discov. Today 13
  
  Pages : 180-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Domain Mapping of A Claudin-4 Modulator, the C-terminal region of C-terminal Fragment of Clostridium perfringens Enterotoxin, by Site-directed Mutagenesis2008
- Author(s)
  Azusa Takahashi, Eriko Komiya, Hideki Kakutani, Takeshi Yoshida, Makiko Fujii, Yasuhiko Horiguchi, Hiroyuki Mizuguchi, Yasuo Tsutsumi, Shin-ichi Tsunoda, Naoya Koizumi, Katsuhiro Isoda, Kiyohito Yagi, Yoshiteru Watanabe and Masuo Kondoh
- Journal Title
  
  Biochem. Pharmacol 75
  
  Pages : 1639-1648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590159
[Journal Article] Evaluation of promoter strength in mouse and rat primaryhepatocytes using adenovirus vectors2008
- Author(s)
  Ar ita E, Kondoh M, Isoda K, Nishimori H, Yoshida T, Mizuguchi H, Yagi K
- Journal Title
  
  Eur J Pharm Biopharm 70
  
  Pages : 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659012
[Journal Article] miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without disturbing the antitumor effects in suicidegene therapy2008
- Author(s)
  Suzuki T, Sakurai F, Nakamura S-I, Kouyama E, Kawabata K, Kondoh M, Yagi K, Mizuguchi H
- Journal Title
  
  Mol Ther 16
  
  Pages : 1719-1726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659012
[Journal Article] Domain mapping of a claudin-4 modulator,the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin,by site-directed mutaenesis.2008
- Author(s)
  Takahashi A, Watanabe Y, Kondoh M., et. al.
- Journal Title
  
  Biochem Pharmacol 8
  
  Pages : 1639-1648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590159
[Journal Article] Role of Tyr306 in the C-terminal fragment of Clostridium perfringens enterotoxin for modulation of tight junction2007
- Author(s)
  Chiaki Ebihara, Masuo Kondoh, Motoki Harada, Makiko Fujii, Hiroyuki Mizuguchi, Shin-ichi Tsunoda, Yasuhiko Horiguchi, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biochem. Pharmacol. 73
  
  Pages : 824-830
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin2007
- Author(s)
  Motoki Harada, Masuo Kondoh, Chiaki Ebihara, Azusa Takahashi, Eriko Komiya, Makiko Fujii, Hiroyuki Mizuguchi, Shin-ichi Tsunoda, Yasuhiko Horiguchi, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biochem. 73
  
  Pages : 206-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin2007
- Author(s)
  Motoki Harada, Masuo Kondoh, Chiaki Ebihara, Azusa Takahashi, Eriko Komiya, Makiko Fujii, Hiroyuki Mizuguchi, Shin-ichi Tsunoda, Yasuhiko Horiguchi, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biochem. Pharmacol. 73
  
  Pages : 206-214
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] The claudin family as a new approach for drug deliver y2007
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Journal Title
  
  Drugs Fut. 32
  
  Pages : 1053-1059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Effect of forskolin on the expression of claudin-5 in human trophoblast BeWo cells2007
- Author(s)
  Motoki Harada, Masuo Kondoh, AkaneMasuyama, Makiko Fujii, Tsuyoshi Nakanishi, naoki Utoguchi, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Pharmazie 62
  
  Pages : 291-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Role of Tyr306 in the C-terminal fragment of Clostridium perfringens enterotoxin for modulation of tight junction2007
- Author(s)
  Chiaki Ebihara, Masuo Kondoh, Motoki Harada, Makiko Fujii, Hiroyuki Mizuguchi, Shin-ichi Tsunoda, Yasuhiko Horiguchi, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biochem. 73
  
  Pages : 824-830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Tight junction modulators: Promising candidates for drug delivery2007
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Journal Title
  
  Curr. Med. Chem. 14
  
  Pages : 2482-2488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Progress in absorption enhancers based on tight junction2007
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Journal Title
  
  Expert Opin. Drug Deliver. 4
  
  Pages : 275-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] タイトジャンクション構成蛋白質claudinを利用した新規薬物送達方法の構築2006
- Author(s)
  近藤昌夫
- Journal Title
  
  薬学雑誌 126
  
  Pages : 711-721
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] A novel strategy for a drug delivery system using a claudin modulator.2006
- Author(s)
  Masuo Kondoh, Azusa Takahashi, Makiko Fujii, Kiyohito Yagi, Yoshiteru Watanabe
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages : 1783-1789
- Data Source
  KAKENHI-PROJECT-18790129
[Journal Article] Characteristics of transcription-regulatory elements for gene expression from plasmid vectors in human trophoblast cell lines.2006
- Author(s)
  Komiya, E., Kondoh, M., Mizuguchi, H., Watanabe, Y, et al.
- Journal Title
  
  Placenta 27
  
  Pages : 934-938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590136
[Journal Article] Efficient gene transfer into differentiated human trophoblast cells with adenovirus vector containing RGD motif in the fiber protein.2006
- Author(s)
  Koizumi, N., Mizuguchi, H., Kondoh, M., Watanabe, Y, et al.
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages : 1297-1299
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590136
[Journal Article] Induction of zinc transporters by forskolin in human trophoblast BeWo cells.2006
- Author(s)
  Asano, N., Kondoh, M., Utoguchi, N., Watanabe, Y, et al.
- Journal Title
  
  Reprod. Toxicol. 21
  
  Pages : 285-291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590136
[Journal Article] Characteristics of transcription-regulatory elements for gene expression from plasmid vectors in human trophoblast cell lines.2006
- Author(s)
  Komiya E, Kondoh M, Watanabe Y., et al.
- Journal Title
  
  Placenta 27
  
  Pages : 934-938
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590136
[Journal Article] Induction of zinc transporters by forskolin in human trophoblast BeWo cells.2006
- Author(s)
  Asano N, Kondoh M, Watanabe Y., et al.
- Journal Title
  
  Reprod. Toxicol. 21
  
  Pages : 285-291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590136
[Journal Article] Comparison of transgene expression mediated by several fiber-modified adenovirus vectors in trophoblast cells.2005
- Author(s)
  小泉直也, 近藤昌夫, 水口裕之, 中西剛, 増山茜, 井田史江, 藤井まき子, 早川尭夫, 中島恵美, 田中慶一, 渡辺善照
- Journal Title
  
  Placenta In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Comparison of transgene expression mediated by several fiber -modifleed Adenovirus vectors in trophoblast cells.2005
- Author(s)
  Naoya Koizumi, Masuo Kondoh, Hiroyuki Mizuguchl, Tsuyoshi Nakanishi, Akane Masuyama, Fumie Ida, Makiko Fujii, Takao Hayakawa, Emi Nakashima, Keiiehi Tanaka, Yoshiteru Watanabe
- Journal Title
  
  Placenta (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] A novel strategy for the enhancement of drug absorption using a claudin modulator2005
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Molecular Pharmacology 67
  
  Pages : 749-756
- Data Source
  KAKENHI-PROJECT-15659041
[Journal Article] Activation of caspase-3 in HL-60 cells treated with pyrithione and zip2005
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Biol.Chem., Bull. 28
  
  Pages : 757-759
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Activation of caspase-3 in HL-60 cells treated with pyrithione and zinc2005
- Author(s)
  M.Kondoh
- Journal Title
  
  Biol.Chem., Bull. 284
  
  Pages : 757-759
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Activation of caspase-3 in HL-60 cells treated with pyrithione and zinc2005
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Biol. Chem., Bull. 284
  
  Pages : 757-759
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Comparison of transgene expression mediated by several fiber-modified adenovirus vectors in trophoblast cells.2005
- Author(s)
  小泉直也, 近藤昌夫, 水口裕之, 中西剛, 増山茜, 井田史江, 藤井まき子, 早川尭夫, 中島恵美, 田中慶一, 渡辺善照
- Journal Title
  
  Placenta (In press)
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Expression profiles of zinc transporters in rodent placental models.2004
- Author(s)
  朝野長祥, 近藤昌夫, 海老原千晶, 藤井まき子, 中西剛, M.J.Soares, 中島恵美, 田中慶一, 渡辺善照
- Journal Title
  
  Toxicological Letters 154
  
  Pages : 45-53
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Efficient gene transfer into human trophoblast cells with adenovirus Vector containing chimeric type 5 and 35 fiber protein.2004
- Author(s)
  Naoya Koizumi, Hiroyuki Mizuguchi, Masuo Kondoh, Makiko Fujii, Takao Hayakawa, Yoshiteriu Watanabe
- Journal Title
  
  Biological Pharmaceutical Bulltein 27
  
  Pages : 2046-2048
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Expression profiles of zinc transpoters in rodent placenta models2004
- Author(s)
  Nagayoshi Asano, Masuo Kondoh, Chiaki Ebihara, Makiko Fujii, Tsuyoshi Nakknishi, Michael J. Soares, Erni Nakashima, Keiiehi Tanaka, Masao Sato, Yoshiteru Watanabe
- Journal Title
  
  Toxicology Letters 154
  
  Pages : 45-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Efficient gene transfer into human trophoblast cells with adeno-virus vector containing chimeric type 5 and 35 fiber protein.2004
- Author(s)
  小泉直也, 水口裕之, 近藤昌夫, 藤井まき子, 早川尭夫, 渡辺善照
- Journal Title
  
  Biological Pharmaceutical Bulltein 27
  
  Pages : 2046-2048
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Induction of hepatic metallothionein synthesis by endoplasmic reticulum stress in mice2004
- Author(s)
  Kondoh, M. et al.
- Journal Title
  
  Toxicol.Lett. 148
  
  Pages : 133-139
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Clasical condition of metallothionein synthesis in mice2004
- Author(s)
  M.Kondoh
- Journal Title
  
  J.Health Sci. 50
  
  Pages : 413-416
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Kauren diterpene induced apoptosis in human leukemia cells partly through a caspase:8-dependent pathway2004
- Author(s)
  M.Kondoh
- Journal Title
  
  J.Pharmacol.Exp.Ther. 311
  
  Pages : 115-122
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Induction of hepatic metallothipnein synthasis byendoplasmic reticulum stress in mice,2004
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Toxicol. Lett. 148
  
  Pages : 133-139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Expression profiles of zinc transporters in rodent placental models.2004
- Author(s)
  朝野長祥, 近藤昌夫, 海老原千晶, 藤井まき子, 中西剛, M.J.Soares, 中島恵美, 田中慶一, 渡辺善照
- Journal Title
  
  Toxicology-Letters 154
  
  Pages : 45-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590139
[Journal Article] Property of metallothionein as a Zn pool differs depending on the induced condition of metallothionein,2003
- Author(s)
  M.Kondoh, et al.
- Journal Title
  
  Toxicol.Lett. 1432
  
  Pages : 11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Antioxidant property of metallothionein in fasted mice2003
- Author(s)
  M.Kondoh, et al.
- Journal Title
  
  Toxicol.Lett. 148
  
  Pages : 301-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Property of metallothionein as Zn pool differs depending on the induced condition of metallothionein2003
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Toxicol. Lett., 143
  
  Pages : 11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Induction of hepatic metallothipnein synthasis by endoplasmic reticulum stress in mice,2003
- Author(s)
  M.Kondoh, et al.
- Journal Title
  
  Toxicol.Lett. 148
  
  Pages : 133-139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Antioxidant property of metallothionein in fasted mice,2003
- Author(s)
  M.Kondoh et al.
- Journal Title
  
  Toxicol. Lett., 143
  
  Pages : 301-306
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370767
[Journal Article] Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis
- Author(s)
  Azusa Takahashi, Eriko Komiya, Hideki Kakutani, Takeshi Yoshida, Makiko Fujii, Yasuhiko Horiguchi, Hiroyuki Mizuguchi, Yasuo Tsutsumi, Shin-ichi Tsunoda, Naoya Koizumi, Katsuhiro Isoda, Kiyohito Yagi, Yoshiteru Watanabe, Masuo Kondoh
- Journal Title
  
  Biochem. Pharmacol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790129
[Presentation] Paracellular or transcellular? Promising approach for oral delivery of macromolecules2014
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Organizer
  2014 AAPS Annual Meeting and Exposition
- Place of Presentation
  SanDiego,　U.S.A.
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮を標的とした創薬基盤研究～Claudin-1を標的とした表皮バリア制御の可能性～2014
- Author(s)
  中嶋美咲、山下真代、渡利彰浩、深澤征義、近藤昌夫、八木清仁
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮を標的とした創薬基盤研究～Tricellular tight junction制御法の開発～2014
- Author(s)
  井口大輔、早石知浩、Susanne M. Krug、Michael Fromm、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮を標的とした創薬基盤研究～Dual specific claudin-3/-4抗体の動態特性および抗癌活性解析～2014
- Author(s)
  木村友香、李相儒、飯田愛未、多田稔、石井明子、國安弘基、深澤征義、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮を標的とした創薬基盤研究～抗claudin-1抗体のエピトープ・交叉性解析～2014
- Author(s)
  畑智幸、長瀬翔太郎、白砂圭崇、深澤征義、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮を標的とした創薬基盤研究～Claudin-4抗体の作製および抗腫瘍活性解析～2014
- Author(s)
  川東祐美、李相儒、國安弘基、多田稔、石井明子、深澤征義、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] A toxicological evaluation of the C-terminal fragment of Clostridium perfringens enterotoxin as a claudin-3/-4 binder2013
- Author(s)
  Iida, M.; Kondoh, M.; Watari, A.; Yagi, K
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Tissue-distributio of claudin-3/-4 binder, the C-terminal fragment of Clostridium perfringens enterotoxin, in mice2013
- Author(s)
  Li, X.; Kondoh, M.; Watari, A.; Yagi, K
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Characterization of scFv libraries derived from mice differently immunized with claudin.2013
- Author(s)
  Yamashita, M.; Nagase, S.; Takahashi, A.; Iwanari, H.; Kondoh, M.; Watari, A.; Hamakubo, T.; Yagi, K
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Development of anti-claudin-1 ligand2013
- Author(s)
  Nagase, S.; Yamashita, M.; Iida, M.; Watari, A.; Kondoh, M.; Fukasawa, M.; Yagi, K
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Effect of claudin on cytochrome P450 activity2013
- Author(s)
  Shimizu, Y.; Kondoh, M.; Watari, A.; Fukasawa, M.; Yagi, K.
- Organizer
  Experimental Biology 2013
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Inhibition of hepatitis C virus infection by mouse anti-claudin 1 monoclonal antibodies2013
- Author(s)
  Fukasawa, M.; Nagase, S.; Yamashita, M.; Iida, M.; Shirasago, Y.; Watari, A.; Suzuki, T.; Wakita, T.; Yagi, K.; Kondoh, M
- Organizer
  HCV2013 20th International Symposium on Hepatittis C virus and Relate viruses 2013
- Place of Presentation
  Melbourne, Australia.
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-1-specific monoclonal antibodies and their inhibition of hepatitis C virus infection2013
- Author(s)
  Nagase, S.; Yamashita, M.; Iida, M.; Shirasago, Y.; Fukasawa, M.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  ILCA 2013: International Liver Cancer Association Seventh Annual Conference
- Place of Presentation
  Washington, D.C. USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Creation of a broadly specific claudin binder and its absorption-enhancing activity2013
- Author(s)
  Doyama, R.; Matsushita, K.; Takahashi, A.; Matsuhisa, K.; Watari, A.; Hamakubo, T.; Yagi, K.; Kondoh, M
- Organizer
  2013 AAPS Annual Meeting and Exposition
- Place of Presentation
  San Antonio, TX, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Bicellular or tricellular tight junction binders and their pharmaceutical activities2013
- Author(s)
  Kondoh, M.; Yagi, K
- Organizer
  Gordon research conference
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Bicellular or tricellular tight junction binders and their pharmaceutical activities2013
- Author(s)
  Kondoh, M.; Yagi, K
- Organizer
  Gordon research seminar,
- Place of Presentation
  Lucca, Italy
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] An improved claudin-targeting mucosal vaccine using a double alanine-substituted mutant of the C-terminal fragment of Clostridium perfringens enterotoxin2013
- Author(s)
  Suzuki, H.; Kunisawa, J.; Yamashita, M.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-1-specific monoclonal antibodies and their inhibition of hepatitis C virus infection2013
- Author(s)
  Nagase, S.; Yamashita, M.; Iida, M.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-1-specific monoclonal antibodies and their inhibitory activity against hepatitis C virus infection2013
- Author(s)
  Nagase, S.; Yamashita, M.; Iida, M.; Shirasago, Y.; Fukasawa, M.; Watari, A.; Yagi, K.; Kondoh, M.
- Organizer
  Antibody Engineering & Terapeutics 2013
- Place of Presentation
  Huntington Beach, CA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Development of claudin-4-specific monoclonal antibodies and their anti-tumor activities2013
- Author(s)
  Iida, M.; Li, X.; Kuniyasu, H.; Fukasawa, M.; Tada, M.; Ishii, A.; Watari, A.; Yagi, K.; Kondoh, M.
- Organizer
  Antibody Engineering & Terapeutics 2013
- Place of Presentation
  Huntington Beach, CA, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第2報～claudin-1抗体のC型肝炎治療への応用～2013
- Author(s)
  飯田愛未、長瀬翔太郎、山下真代、近藤昌夫、八木清仁、國安弘基、深澤征義
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] ウエルシュ菌イオタ毒素を用いた tricellular tight junction制御法の開発2013
- Author(s)
  早石知浩、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第60回トキシンシンポジウム
- Place of Presentation
  兵庫
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Tissue-distribution and safety evaluation of a claudin-3/-4 binder in mice2013
- Author(s)
  Li, X.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  53rd Annual meeting of the American society for cell biology
- Place of Presentation
  New Orleans, LO, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] In vitro and in vivo inhibition of hepatitis C virus infection by mouse anti-human claudin 1 monoclonal antibodies2013
- Author(s)
  Fukasawa, M.; Nagase, S.; Yamashita, M.; Iida, M.; Shirasago, Y.; Hanada, K.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  53rd Annual meeting of the American society for cell biology
- Place of Presentation
  New Orleans, LO, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Identification of chemical compounds that modulate claudin-4 expression by cell-based screening2013
- Author(s)
  Watari, A.; Hasegawa, M.; Yagi, K.; Kondoh, M
- Organizer
  53rd Annual meeting of the American society for cell biology
- Place of Presentation
  New Orleans, LO, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮バリアを標的とした創薬研究の新展開2013
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  日本膜学会第35年会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第１報～claudin-1特異性抗体の創製～2013
- Author(s)
  長瀬翔太郎、山下真代、、飯田愛未、渡利彰浩、近藤昌夫、深澤征義、多田稔、石井明子、八木清仁
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第３報～claudin-4特異性抗体の創製～2013
- Author(s)
  清水芳実、李相儒、渡利彰浩、近藤昌夫、深澤征義、多田稔、石井明子、國安弘基、八木清仁
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮バリア制御による薬物吸収促進研究の新展開2013
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  第29回日本DDS学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudinを標的とした粘膜ワクチン技術の開発2013
- Author(s)
  土山遼、鈴木英彦、角谷英樹、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第32回分子病理研究会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-3/-4結合分子(C-CPE)を利用する体内動態および安全性解析2013
- Author(s)
  李相儒、近藤昌夫、渡利彰浩、八木清仁
- Organizer
  日本薬物動態学会　第28年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-3 and -4 binderの体内動態解析および安全性評価2013
- Author(s)
  李相儒、近藤昌夫、渡利彰浩、八木清仁
- Organizer
  第32回分子病理研究会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudinを標的とした粘膜吸収促進法の開発2013
- Author(s)
  飯田愛未、鈴木英彦、李相儒、近藤昌夫、渡利彰浩、八木清仁
- Organizer
  第32回分子病理研究会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 抗Claudin-1抗体の創製と評価2013
- Author(s)
  山下真代、長瀬翔太郎、飯田愛未、白砂圭崇、深澤征義、近藤昌夫、多田　稔、石井明子、渡利彰浩、八木清仁
- Organizer
  日本薬物動態学会　第28年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第1報～Claudin binderのバアリ制御機構の解析～2013
- Author(s)
  土山遼、Susanne M Krug、Michael From、近藤昌夫、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Development of monoclonal antibodies to the extracellular loop regions of claudin-1 and their application to HCV therapy2013
- Author(s)
  Nagase, S.; Yamashita, M.; Iida, M.; Fukasawa, M.; Watari, A.; Yagi, K.; Kondoh, M
- Organizer
  2013 AAPS Annual Meeting and Exposition
- Place of Presentation
  San Antonio, TX, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] タイトジャンクションによる薬物代謝活性制御の可能性2013
- Author(s)
  清水芳実、近藤昌夫、渡利彰浩、深潭征義、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第7報～Claudin-3/-4結合分子(C-CPE)の体内動態解析～2013
- Author(s)
  李相儒、近藤昌夫、渡利彰浩、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第6報～Tricellular junction modulatorの創製～2013
- Author(s)
  早石知浩、近藤昌夫、渡利彰浩、永浜正博、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第5報～低分子tight junction modulator の創製～2013
- Author(s)
  長谷川真希、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第4報～Claudin-binder-4特異的binderの創製～2013
- Author(s)
  平垣有史、李相儒、清水芳実、渡利彰浩、近藤昌夫、深潭征義、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第3報～Claudin-1特異的binderの創製～2013
- Author(s)
  長瀬翔太郎、山下真代、飯田愛未、渡利彰浩、近藤昌夫、深潭征義, 八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 上皮細胞を標的とした創薬基盤研究第2報～免疫抗体ライブラリの最適化～2013
- Author(s)
  山下真代、長瀬翔太郎、高橋梓、岩成宏子、近藤昌夫、渡利彰浩、浜窪隆雄、八木清仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] 新規 claudin binder（m19）の結合特性および機能ドメイン解析2012
- Author(s)
  鈴木英彦、髙橋梓、松下恭平、李相儒、辻野博文、近藤昌夫、青山浩、渡利彰浩、宇野公之、八木清仁
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] MDCK細胞におけるタイトジャンクション機能への Sec61β 遺伝子の影響2012
- Author(s)
  鷲山真紀子、小泉直也、佐々木杏沙、松本有未、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin-4 modulatorの同定を目指したclaudin発現モニタリングシステムの開発2012
- Author(s)
  渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] MDCK細胞におけるタイトジャンクション機能へのSec61b遺伝子の関与2012
- Author(s)
  鷲山真紀子、小泉直也、佐々木杏沙、松本有未、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] MDCK細胞におけるタイトジャンクション機能へのSec61b遺伝子の関与2012
- Author(s)
  鷲山真紀子、小泉直也、佐々木杏沙、松本有未、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] Human iPS-derived hepatocyte-like cells as a model for hepatitis C virus infection2012
- Author(s)
  Seiji Yamane, T.Yoshida, K.Takayama, Masuo Kondoh, F.Sakurai, H.Mizuguchi and Kiyohito Yagi
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Evaluation of HCV infection and replication using human iPS cell-derived hepatocytes2012
- Author(s)
  Kiyohito Yagi, Takeshi Yoshida, Seiji Yamane, Kazuo Takayama, Akihiro Watari, Masuo Kondoh, Fuminori Sakurai, Naoya Sakamoto, Yoshiharu Matsuura, Hiroyuki Mizuguchi
- Organizer
  19th International Symposium on Hepatittis C virus and Relate viruses
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] 高親和性claudin-4 binderの創製と粘膜ワクチンへの応用2012
- Author(s)
  鈴木英彦、山根誠司、角谷英樹、高橋梓、内田博司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Preparation of a broad-specific claudin binder by using Clotridium perfringcns enterotoxin.2012
- Author(s)
  Hidehiko Suzuki, Azusa Takahashi, Koji Mat sushita, Xiangru Li, Hiroshi Tsujino, Akihiro Watari, Masuo Kondoh, Hiroshi Aoyama, Tadayuki Uno, Kiyohito Yagi
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] アデノウイルスベクターを利用した C 型肝炎研究の新展開2012
- Author(s)
  近藤昌夫、水口裕之、八木清仁
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] ヒト iPS 細胞由来肝細胞を用いた HCV 感染モデルの作製2012
- Author(s)
  山根誠司、吉田孟史、高山和雄、近藤昌夫、桜井文教、谷英樹、坂本直哉、松浦善治、水口裕之、八木清仁
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Evaluation of HCV infection and replication using human iPS cell-derived hepatocytes2012
- Author(s)
  Kiyohito Yagi, Takeshi Yoshida, Seiji Yamane, Kazuo Takayama, Akihiro Watari, Masuo Kondoh, Fuminori Sakurai, Naoya Sakamoto, Yoshiharu Matsuura, Hiroyuki Mizuguchi
- Organizer
  19thInternational Symposium on Hepatittis C virus and Relate viruses 2012
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Human iPS-derived hepatocyte-like cells as a model for hepatitis C virus infection2012
- Author(s)
  Seiji Yamane, Takeshi Yoshida, Kazuo Takayama, Masuo Kondoh, Fuminori Sakurai, Hiroyuki Mizuguchi, Kiyohito Yagi
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Creation of a novel claudin binder by using Clostridium perfringens enterotoxin and baculoviral display.2012
- Author(s)
  Azusa Takahashi, Yumiko Saito, Masuo Kondoh, Hideki Kakutani, Hidehiko Suzuki, Koji Matsuhisa, Akihiro Watari, Takao Hamakubo, Kiyohito Yagi
- Organizer
  52nd Annual meeting of the American society for Ce11 Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Biochemical analysis of a claudin ligand that exhibits a broad binding specificity2012
- Author(s)
  Ryo Doyama, Hidehiko Suzuki, Kyohei Matsushita、Xiangru Li, Azusa Takahashi, Koji Matsuhisa, Hiorshi Tsujino, Akihiro Watari、Masuo Kondoh, Hiroshi Aoyama, Tadayuki Uno, Kiyohito Yagi
- Organizer
  Tight junction conference 2012
- Place of Presentation
  Merida, MEXICO
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] タイトジャンクションを標的とした粘膜吸収促進技術の螺旋的発展2012
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  第34生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  京都市(招待講演)
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudinを標的とした動態制御技術の現状と課題2012
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  創剤フォーラム第18回若手研究会講演
- Place of Presentation
  徳島市(招待講演)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Structual and biochemical analysis of a novel, broadly specific claudin binder2012
- Author(s)
  Shotaio Nagase, Koj i Matsushita, Azusa Takahashi, Hiroshi Tsujino, Xiangru Li, Hidehiko Suzuki, Hiroshi. Aoyama, Masuo Kondoh, Akihiro Watari, Tadayuki Uno, Takao Hamakubo, Kiyohito Yagi
- Organizer
  52nd Annual meeting of the American society for Ce11 Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudinを標的とした動態制御技術の現状と課題2012
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  第28回日本DDS学会学術集会
- Place of Presentation
  札幌市(招待講演)
- Year and Date
  2012-07-04
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Clostridium perfringens enterotoxin 断片を利用したclaudin指向性吸収促進技術の安全性評価2012
- Author(s)
  土山遼、長瀬翔太郎、鈴木英彦、李相儒、山根誠司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第59回トキシンシンポジウム
- Place of Presentation
  帯広市
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Spiral progression in epithelium-target ed drug development2012
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Organizer
  International Symposium on Epithelial Barrier and Transport 2012
- Place of Presentation
  草津市(招待講演)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Establishment of a cell-based screening system for chemical modulators of claudin expression2012
- Author(s)
  Akihiro Watari, Maki Hasegawa, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Tight junction conference 2012
- Place of Presentation
  Merida, MEXICO
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Establishment of a cell-based assay system to screen compounds modulating tight junction barrier.2011
- Author(s)
  Akihito Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  51st annual meeting of the American society for cell biology
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of claudin-4 binder using C-terminal fragment of Clostridium perfringens enterotoxin and its application to mucosal vaccination.2011
- Author(s)
  Hidehiko Suzuki, Seiji Yamane, Akihiro Watari, Masuo Kondoh, Hiroshi Uchida, Kiyohito Yagi
- Organizer
  51st annual meeting of the American society for cell biology
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A simple screening system for claudin binders using an scFv library derived from claudin-immunized mice.2011
- Author(s)
  Miki Kodaka, Azusa Takahashi, Toshiaki Yamaura, Yohei Kakamu, Koji Matsuhisa, Kyohei Matsushita, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of claudin binders using bacuroviral displaying system.2011
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Organizer
  Tight junction conference in Berlin
- Place of Presentation
  Berlin, Germany.
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel strategy for mucosal vaccination using a claudin binder.2011
- Author(s)
  Seiji Yamane, Hidehiko Suzuki, Hideki Kakutani, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  38th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  National Harbor, MA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Dual specific claudin binderを利用した非侵襲性投与技術の開発2011
- Author(s)
  髙橋梓、斉藤郁美子、松久幸司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin欠損マウスを利用したclaudin binder創製系の確立2011
- Author(s)
  各務洋平、高橋梓、山浦利章、松久幸司、近藤昌夫、浜窪隆雄、八木清仁
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Establishment of a cell-based assay system to screen compounds modulating tight junction barrier2011
- Author(s)
  Akihito Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  51st annual meeting of the American society for cell biology
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of claudin-4 binder using C-terminal fragment of Clostridium perfringens enterotoxin and its application to mucosal vaccination2011
- Author(s)
  Hidehiko Suzuki, Seiji Yamane, Akihiro Watari, Masuo Kondoh, Hiroshi Uchida, Kiyohito Yagi
- Organizer
  51st annual meeting of the American society for cell biology
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a novel claudin binder and its application into mucosal absorption2011
- Author(s)
  Azusa Takahashi, Yumiko Saito, Yohei Kakamu, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  日本薬物動態学会第26回年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Clostridium perfringens enterotoxin を利用したドラッグデリバリーシステムの開発2011
- Author(s)
  松久幸司、髙橋梓、角谷秀樹、佐伯理恵、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第58回トキシンシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Clostridium perfringens enterotoxin変異体m19のclaudin結合性解析2011
- Author(s)
  髙橋梓、松下恭平、斉藤郁美子、嵩原綱吉、各務洋平、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第58回トキシンシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Identification of tight junction-modulating compounds by claudin expression monitoring system2011
- Author(s)
  Akihito Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  日本薬物動態学会第26回年会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 新規claudin binder C-CPEm19の機能ドメイン解析2011
- Author(s)
  各務洋平、松下恭平、高橋梓、松久幸司、斉藤郁美子、青山浩、宇野公之、近藤昌夫、八木清仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 新規claudin binderの創製と粘膜ワクチンへの応用2011
- Author(s)
  山根誠司、鈴木英彦、角谷秀樹、高橋梓、松久幸司、内田博司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin発現モニタリングシステムを用いたTight junction調節物質の検索2011
- Author(s)
  渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin modulatorを利用した粘膜吸収促進法の現状と課題2011
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡(招待講演)
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Targeting to claudin-4 is a novel strategy for the development of mucosal vaccine.2011
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Akihiro Fukasaka, Masuo Kondoh, Kiyohito Yagi
- Organizer
  The 7th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientist 6
- Place of Presentation
  Seoul National University, Korea
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of an RNA polymerase I-driven aden2011
- Author(s)
  T. Yoshida, F. Satoh, A. Watari, M. Kondoh, et al.
- Organizer
  18th International Symposium of Hepatitis C
- Place of Presentation
  Seattle, WA, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Preparation of a dual claudin binder using a fragment of Clostridium perfringens enterotoxin.2011
- Author(s)
  Azusa Takahashi, Yumiko Saito, Koji Matsuhisa, Yohei Kakamu, Miki Kodaka, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a novel claudin binder using baculoviral display for its application in mucosal absorption of drugs.2011
- Author(s)
  Koji Matsuhisa, Azusa Takahashi, Yohei Kakamu, Miki Kodaka, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  38th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  National Harbor, MA, USA.
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] タイトジャンクションバリアー機能に関与する遺伝子の解析2011
- Author(s)
  鷲山真紀子、小泉直也、苅込亜美、佐々木杏沙、松本有未、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東邦大学習志野キャンパス(千葉県)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] Caco-2細胞におけるタイトジャンクション開閉時での遺伝子発現変動の解析2011
- Author(s)
  苅込亜美、小泉直也、佐々木杏沙、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  日本薬学会第131年会
- Place of Presentation
  要旨集上で発表
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] タイトジャンクションバリアー機能に関与する遺伝子の解析2011
- Author(s)
  鷲山真紀子、小泉直也、苅込亜美、佐々木杏沙、松本有未、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  東邦大学習志野キャンパス(千葉県)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] Development of novel claudin-4 binder and its application in mucosal vaccine2011
- Author(s)
  Kiyohito Yagi, Seiji Yamane, Hidehiko Suzuki, Akihiro Watari, Masuo Kondoh, Hiroshi Uchida
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Biochemical analysis of a novel dual claudin binder.2011
- Author(s)
  Yohei Kakamu, Kyohei Matsushita, Yumiko Saito, Azusa Takahashi, Koji Matsuhisa, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a novel claudin binder using baculoviral display for its application in mucosal absorption of drugs2011
- Author(s)
  Koji Matsuhisa, Azusa Takahashi, Yohei Kakamu, Miki Kodaka, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  38th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  National Harbor, MA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Targeting to claudin-4 is a novel strategy for the development of mucosal vaccine2011
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Akihiro Fukasaka, Masuo Kondoh, Kiyohito Yagi
- Organizer
  The 7th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientist 6
- Place of Presentation
  Seoul National University, Korea
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of a dual claudin binder using a fragment of Clostridium perfringens enterotoxin2011
- Author(s)
  Azusa Takahashi, Yumiko Saito, Koji Matsuhisa, Yohei Kakamu, Miki Kodaka, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel strategy for mucosal vaccination using a claudin binder2011
- Author(s)
  Seiji Yamane, Hidehiko Suzuki, Hideki Kakutani, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  38th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  National Harbor, MA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Caco-2細胞におけるタイトジャンクション開閉時での遺伝子発現変動の解析2011
- Author(s)
  苅込亜美、小泉直也、佐々木杏沙、藤井まき子、近藤昌夫、八木清仁、渡辺善照
- Organizer
  日本薬学会第131年会
- Place of Presentation
  誌上発表
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-21590178
[Presentation] A simple screening system for claudin binders using an scFv library derived from claudin-immunized mice2011
- Author(s)
  Miki Kodaka, Azusa Takahashi, Toshiaki Yamaura, Yohei Kakamu, Koji Matsuhisa, Kyohei Matsushita, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin binderを利用した創薬基盤研究2011
- Author(s)
  高橋梓、近藤昌夫、八木清仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡(招待講演)
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] RNA ポリメラーゼ I 発現系を利用した長鎖 RNA 発現ベクターの開発2011
- Author(s)
  吉田孟史、佐藤芙美、渡利彰浩、近藤昌夫、水口裕之、八木清仁
- Organizer
  第27回日本DDS 学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Takeshi Yoshida, Fumi Satoh, Akihito Watari, Masuo Kondoh, Hiroyuki Mizuguchi, Naoya Sakamoto, Kiyohito Yagi
- Organizer
  18thInternational Symposium of hepatitis C virus and related viruses
- Place of Presentation
  Seattle, WA, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Masuo Kondoh, Yoshiaki Yamagishi, Takeshi Yoshida, Hiroyuki Mizuguchi, Naoya Sakamoto, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Development of RNA pol-driven adenovirus vecto2011
- Author(s)
  M. Kondoh, Y. Yamagishi, et al.
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Biochemical analysis of a novel dual claudin binder2011
- Author(s)
  Yohei Kakamu, Kyohei Matsushita, Yumiko Saito, Azusa Takahashi, Koji Matsuhisa, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a Mucosal Vaccine Using a Claudin-4 Binder.2010
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  FIP Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel strategy for cancer-targeting using claudin-4 binder.2010
- Author(s)
  Hidehiko Suzuki, Rie Saeki, Masuo Kondoh, Kiyohito Yagi
- Organizer
  37th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  Portland, OR, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a non-invasive drug delivery system using a claudin modulator2010
- Author(s)
  Yohei Kakamu, Hiroshi Uchida, Takeshi Hanada, Azusa Takahashi, Masuo Kondoh, Kiyohito Yagi
- Organizer
  FIP Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A claudin-4 modulator enhances the mucosal absorption of peptide.2010
- Author(s)
  Hiroshi Uchida, Masuo Kondoh, Takeshi Hanada, Azusa Takahashi, Takao Hamakubo, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of a claudin-4-targeted anti-tumor molecule.2010
- Author(s)
  Masuo Kondoh, Rie Saeki, Hideki Kakutani, Yasuhiro Mochizuki, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin-4 binderを利用した粘膜ワクチンの開発2010
- Author(s)
  鈴木英彦、角谷秀樹、深坂昌弘、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudinを利用したペプチド医薬品の非侵襲性投与技術の開発2010
- Author(s)
  各務洋平、内田博司、花田雄志、高橋梓、山浦利章、松久幸司、近藤昌夫、八木清仁
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of mucosal vaccine using a claudin binder2010
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Takeshi Yoshida, Masuo Kondoh, Kiyohito Yagi
- Organizer
  50th annual meeting of the American society for cell biology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin-4を標的とした癌ターゲッティング法の開発2010
- Author(s)
  松久幸司、佐伯理恵、角谷秀樹、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a Mucosal Vaccine Using a Claudin-4 Binder2010
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
- Organizer
  FIP Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  Louisiana, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a non-invasive drug delivery system using a claudin modulator2010
- Author(s)
  Yohei Kakamu, Hiroshi Uchida, Takeshi Hanada, Azusa Takahashi, Masuo Kondoh, Kiyohito Yagi
- Organizer
  FIP Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  Louisiana, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A claudin-4 modulator enhances the mucosal absorption of peptide2010
- Author(s)
  Hiroshi Uchida, Masuo Kondoh, Takeshi Hanada, Azusa Takahashi, Takao Hamakubo, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel strategy for cancer-targeting using claudin-4 binder2010
- Author(s)
  Hidehiko Suzuki, Rie Saeki, Masuo Kondoh, Kiyohito Yagi
- Organizer
  37th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  Portland, OR, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a novel nasal vaccine using a claudin-4 binder2010
- Author(s)
  Hidehiko Suzuki, Masuo Kondoh, Hideki Kakutani, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of a claudin-4-targeted anti-tumor molecule2010
- Author(s)
  Masuo Kondoh, Rie Saeki, Hideki Kakutani, Yasuhiro Mochizuki, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin-4 binderを標的とした新規粘膜ワクチンの創製2010
- Author(s)
  鈴木英彦、角谷秀樹、深坂昌弘、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  日本ワクチン学会第14年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Clostridium perfringens enterotoxinを利用したclaudin-1 binderの創製2010
- Author(s)
  高橋梓、斉藤郁美子、松久幸司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudinを標的とした非侵襲性投与技術の開発2010
- Author(s)
  高橋梓、松久幸司、各務洋平、近藤昌夫、八木清仁
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Clostridium perfringens enterotoxinを利用した非侵襲性投与法の開発2010
- Author(s)
  高橋梓、松久幸司、各務洋平、内田博司、花田雄志、近藤昌夫、八木清仁
- Organizer
  第57回トキシンシンポジウム
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 新規claudin modulatorの創製およびドラッグデリバリーシステムへの応用2010
- Author(s)
  各務洋平、高橋梓、松下恭平、松久幸司、近藤昌夫、八木清仁
- Organizer
  第9回次世代を担う若手ファーマ・バイオフォーラム2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 高親和性claudin binderの創製およびドラッグデリバリーシステムへの応用2010
- Author(s)
  各務洋平、内田博司、花田雄志、高橋梓、近藤昌夫、八木清仁
- Organizer
  BIA symposium 2010
- Place of Presentation
  東京
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] claudin modulator as a mucosal absorption-enhancer of a peptide drug2010
- Author(s)
  Yohei Kakamu, Hiroshi Uchida, Takeshi Hanada, Azusa Takahashi, Masuo Kondoh, Kiyohito Yagi
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin modulatorを利用した非侵襲的投与技術の開発2010
- Author(s)
  松下恭平、高橋梓、斉藤郁美子、松久孝司、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第9回次世代を担う若手ファーマ・バイオフォーラム2010
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel screening system for claudin binder using baculovira 1 display2010
- Author(s)
  Azusa Takahashi, Masuo Kondoh, Hideki Kakutani, Toshiko Sakihama, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudin binderを利用した癌治療法の開発2010
- Author(s)
  鈴木英彦、佐伯理恵、角谷秀樹、渡利彰浩、近藤昌夫、八木清仁
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Development of a novel nasal vaccine using a claudin-4 binder2010
- Author(s)
  Hidehiko Suzuki, Masuo Kondoh, Hideki Kakutani, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] A novel screening system for claudin binder using baculoviral display.2010
- Author(s)
  Azusa Takahashi, Masuo Kondoh, Hideki Kakutani, Toshiko Sakihama, Takao Hamakubo, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2010
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Preparation of a controllable RNA polymerase I-dependent expression vector2009
- Author(s)
  Takeshi Yoshida, Manabu Ojima, Masuo Kondoh, Hiroyuki Mizuguchi, Kiyohito Yagi
- Organizer
  49^<th> Annual Meeting of the American Society of Cell Biology
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-20659012
[Presentation] 増殖性ウイルスが出現しないアデノウイルスベクター作製法の開発2009
- Author(s)
  矢野小代里, 鈴木孝幸, 佐々木朋美, 楼井文教, 川端健二, 近藤昌夫, 八木清仁, 水口裕之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20659012
[Presentation] 創薬ターゲットとしてのタイトジャンクションの可能性2009
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  創剤フォーラム第15回シンポジウム「タイトジャンクションをめぐる最近の研究成果と創薬への応用」
- Place of Presentation
  東京
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 生体バリアを利用した薬物送達研究2009
- Author(s)
  近藤昌夫
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 生体バリアの分子基盤を利用した創薬研究2009
- Author(s)
  近藤昌夫
- Organizer
  第25回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 生体バリアの分子基盤を利用した経粘膜DDS2009
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  第25回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Claudinを利用した創薬研究の可能性2009
- Author(s)
  近藤昌夫
- Organizer
  彩都バイオサイエンスセミナー
- Place of Presentation
  大阪
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 転写制御型RNA polymerase I 発現系ベクターの創製2009
- Author(s)
  吉田孟史, 尾島学, 磯田勝広, 近藤昌夫, 水口裕之, 八木清仁
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20659012
[Presentation] ヒト結腸由来Caco-2細胞におけるtight junction分子機構の解析を目的としたclaudin発現システムの確立2009
- Author(s)
  仙内光子,山岸喜彰,小泉直也,水口裕之,近藤昌夫,八木清人,藤井まき子,渡辺善照
- Organizer
  日本薬学会第129年会
- Data Source
  KAKENHI-PROJECT-19590159
[Presentation] ウェルシュ菌エンテロトキシンC末断片(C-CPE)作用時の小腸粘膜上皮細胞における変動遺伝子の解析2008
- Author(s)
  仙内光子、小泉直也、大内可成子、浜田華香、近藤昌夫、藤井まき子、八木清仁、渡辺善照
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790129
[Presentation] ウェルシュ菌エンテロトキシン断片を利用したclaudin-4ターゲッテイング法の開発2008
- Author(s)
  佐伯理恵、角谷秀樹、吉田孟史、深坂昌弘、磯田勝広、鈴木亮、近藤昌夫、渡邊善照、丸山一雄、八水漬仁
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790129
[Presentation] Tight junction modulatorと粘膜デリバリー2008
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18790129
[Presentation] ウエルシュ菌エンテロトキシンC末断片(C-CPE)作用時の小腸粘膜上皮細胞における変動遺伝子の解析2008
- Author(s)
  仙内光子,小泉直也,大内可成子,浜田華香,近藤昌夫,藤井まき子,八木清仁,渡辺善照
- Organizer
  日本薬学会第128年会
- Data Source
  KAKENHI-PROJECT-19590159
[Presentation] ウエルシュ菌エンテロトキシンC末断片(C-CPE)を利用したclaudin-4ターゲティング法の開発2008
- Author(s)
  佐伯理恵,角谷秀樹,吉田孟史,深坂勝広,鈴木亮,近藤昌夫,渡辺善照,丸山一雄,八木清仁
- Organizer
  日本薬学会第128年会
- Data Source
  KAKENHI-PROJECT-19590159
[Presentation] Development of a conventional assay system for HCV replicationusing RNA polymerase I-dependent expression plasmid2008
- Author(s)
  Yoshida T, Ojima M, Kondoh M, Yagi K
- Organizer
  48^<th> Annual Meeting of the American Society of Cell Biology
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-20659012
[Presentation] A novel drug delivery system using a claudin modulator2007
- Author(s)
  Masuo Kondoh, Makiko Fujii, Katsuhiro Isoda, Yoshiteru Watanabe, Kiyohito Yagi
- Organizer
  PSWC2007
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-18790129
[Presentation] Modulation of the epithelial bariier by a fragment of Clostridium perfringens iota-toxin
- Author(s)
  D.Iguchi, T.Hayaishi, S.M. Krug, A.Watari, M.Fromm, K.Yagi and M.Kondoh
- Organizer
  Experimental Biology 2014
- Place of Presentation
  SanDiego,U.S.A.
- Year and Date
  2014-04-26 – 2014-04-30
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Development of mucosal vaccine using a claudin binder.
- Author(s)
  Hidehiko Suzuki, Hideki Kakutani, Takeshi Yoshida, Masuo Kondoh, Kiyohito Yagi
- Organizer
  50th annual meeting of the American society for cell biology
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] Anti-human claudin-1 monoclonal antbodies as anti-Hepatitis C Virus agents
- Author(s)
  M. Iida, M. Yamashita, S. Nagase, M. Tada, Y. Shirasago, M. Fukasawa, A.Watari, A.Ishii-Watabe, K. Yagi, M. Kondoh
- Organizer
  Antibody Engineering & Therapeutics 2014
- Place of Presentation
  Huntington Beach, CA, U.S.A.
- Year and Date
  2014-12-07 – 2014-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudinを標的とした非侵襲性投与技術の開発
- Author(s)
  髙橋梓、斉藤郁美子、近藤昌夫、八木清仁
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] RNAポリメラーゼI発現系を利用した長鎖RNA発現ベクターの開発
- Author(s)
  吉田孟史、佐藤芙美、渡利彰浩、近藤昌夫、水口裕之、八木清仁
- Organizer
  第２７回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] ヒトiPS細胞由来肝細胞を用いたHCV感染モデルの作製
- Author(s)
  山根誠司、吉田孟史、高山和雄、近藤昌夫、櫻井文教、谷英樹、坂本直哉、松浦善治、水口裕之、八木清仁
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] Development of claudin binders using bacuroviral displaying system
- Author(s)
  Masuo Kondoh, Kiyohito Yagi
- Organizer
  Tight junction conference in Berlin
- Place of Presentation
  Berlin, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-21689006
[Presentation] 第29回日本DDS学会
- Author(s)
  近藤昌夫、八木清仁
- Organizer
  第66回日本細菌学会中国・四国支部総会
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Claudin-1 as a target for modulation of epidermal barriers
- Author(s)
  M.Nakajima, M.Yamashita, A.Watari, K.Yagi, M.Fukasawa, and M.Kondoh
- Organizer
  Experimental Biology 2014
- Place of Presentation
  SanDiego,U.S.A.
- Year and Date
  2014-04-26 – 2014-04-30
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Epitope mapping of an anti-claudin-1 monoclonal antibody and its application to preclinical drug discovery
- Author(s)
  T. Hata, S. Nagase, Y. Shirasago, M. Fukasawa, A. Watari, K. Yagi, M. Kondoh
- Organizer
  Antibody Engineering & Therapeutics 2014
- Place of Presentation
  Huntington Beach, CA, U.S.A.
- Year and Date
  2014-12-07 – 2014-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] アデノウイルスベクターを利用したC型肝炎研究の新展開
- Author(s)
  近藤昌夫、水口裕之、八木清仁
- Organizer
  日本薬学会第１３２年会(招待講演)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659039
[Presentation] In vivo inhibition of hepatitis C virus infection by anti-claudin-1 monoclonal antibodies
- Author(s)
  M.Iida, S.Nagase, M.Yamashita, Y.Shirasago, M.Fukasawa, M.Tada, A.Ishii, A.Watari,　K.Yagi, and M.Kondoh
- Organizer
  The 41st Annual Meeting & Exposition of the controlled Release Society
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2014-07-13 – 2014-07-16
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Development of a Novel Bispecific Anti-Claudin Antibody and its Anti-Tumor Activity
- Author(s)
  Y. Kimura, X. Li, M. Iida, M. Tada, A. Watabe-Ishii, M. Fukasawa, Y. Kawahigashi, A. Watari, K. Yagi, M. Kondoh
- Organizer
  Antibody Engineering & Therapeutics 2014
- Place of Presentation
  Huntington Beach, CA, U.S.A.
- Year and Date
  2014-12-07 – 2014-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-24390042
[Presentation] Tumor-targeting and anti-tumor activity of anti-claucin-3/-4 antibody
- Author(s)
  Y.Kimura, X.Li, M.Iida, M.Tada, A.Ishii, A.Watari, M.Fukasawa, K.Yagi and M.Kondoh
- Organizer
  Experimental Biology 2014
- Place of Presentation
  SanDiego,U.S.A.
- Year and Date
  2014-04-26 – 2014-04-30
- Invited
- Data Source
  KAKENHI-PROJECT-24390042

1. WATANABE Yoshiteru (70175131)

# of Collaborated Projects : 6results

# of Collaborated Products : 27results
2. FUJII Makiko (50199296)

# of Collaborated Projects : 5results

# of Collaborated Products : 20results
3. KOIZUMI Naoya (80433845)

# of Collaborated Projects : 4results

# of Collaborated Products : 11results
4. SATO Masao (20045743)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. TSUNODA Tetsuto (00172049)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. Aoyama Hiroshi (60291910)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 八木清仁 (70166479)

# of Collaborated Projects : 1results

# of Collaborated Products : 7results
8. Akihiro Watari

# of Collaborated Projects : 0results

# of Collaborated Products : 4results
9. Fukasawa Masayoshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 國安弘基

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
11. 脇田隆字

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 鈴木亮介

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 鈴木哲朗

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

KONDOH Masuo 近藤 昌夫

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血液脳関門シールド制御による脳内薬物送達技術の開発への挑戦Principal InvestigatorOngoing

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Claudin-1 as a target for modulation of epidermal barriersPrincipal Investigator

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Development ofan assay system for hepatitis C virus in micePrincipal Investigator

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Development of non-invasive drug delivery system using claudin modulatorPrincipal Investigator

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RNAポリメラーゼI発現系を利用したC型肝炎ウイルス増幅系の開発Principal Investigator

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Claudin modulatorを利用した新規薬物送達方法の構築Principal Investigator

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タイトジャンクション構成分子Claudinを標的とした新規吸収促進戦略の確立Principal Investigator

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KONDOH Masuo 近藤昌夫