ASANO Satoshi 浅野智志

Researcher Number	30570535
Affiliation *help	2016 – 2018 : 広島大学, 医歯薬保健学研究科(歯), 助教 2013 – 2018 : 広島大学, 医歯薬保健学研究院(歯), 助教 2015 : 広島大学, 医歯薬保健学研究院, 助教 2015 : 広島大学, 大学院医歯薬保健学研究院, 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 細胞移動 / 細胞増殖 / PI3-kinase / イノシトールリン脂質 / PI(4,5)P2 / 転移 / アポトーシス / 血小板増殖因子 / 細胞分裂 / 癌 … More Except Principal Investigator 浸潤・転移 / リン脂質代謝 / 脂肪細胞 / 分化 / ベージュ細胞 / 癌 / 脱分化 / 脂肪代謝 / エネルギー代謝 / 癌転移 / 寒冷刺激 / 細胞周期 / シグナル伝達 / 細胞運動 / 脂肪分化 / イノシトールリン脂質結合性タンパク質 / がん細胞浸潤・転移 / 癌細胞浸潤 / 白色脂肪細胞 / 褐色脂肪細胞 / 細胞増殖 Less

PRIPの新奇癌細胞制御機構に着目した抗腫瘍薬開発研究Principal InvestigatorOngoing
- Principal Investigator
  
  浅野智志
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
膜リン脂質代謝変調がもたらす癌増悪メカニズムの解明研究Ongoing
- Principal Investigator
  
  兼松隆
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hiroshima University
Studied on the mechanisms of cancer metastasis and proliferation regulated by a new moleculePrincipal Investigator
- Principal Investigator
  
  Asano Satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.
- Principal Investigator
  
  Kanematsu Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
The study of blood clotting and venous repair regulated by a novel proteinPrincipal Investigator
- Principal Investigator
  
  ASANO Satoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice.2018
- Author(s)
  Yamawaki Y, Yoshioka N, Nozaki K, Ito H, Oda K, Harada K, Shirawachi S, Asano S, Aizawa H, Yamawaki S, Kanematsu T, Akagi H
- Journal Title
  
  Brain Research
  
  Volume : 1;1680 Pages : 13-38
- DOI
  10.1016/j.brainres.2017.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K19459, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16H07001, KAKENHI-PROJECT-17K11670
[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice2017
- Author(s)
  Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
- Journal Title
  
  J Anesth
  
  Volume : in press Pages : 531-538
- DOI
  10.1007/s00540-017-2350-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
[Journal Article] Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling.2017
- Author(s)
  Asano Satoshi、Taniguchi Yuri、Yamawaki Yosuke、Gao Jing、Harada Kae、Takeuchi Hiroshi、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Scientific reports
  
  Volume : 7 Pages : 5408-5408
- DOI
  10.1038/s41598-017-05908-7
- Peer Reviewed / Int'l Joint Research / Open Access
- Data Source
  KAKENHI-PROJECT-16K11479, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-15K11039
[Journal Article] Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance2017
- Author(s)
  Sano T et al.
- Journal Title
  
  Nutr Metab Cardiovasc Dis.
  
  Volume : 27 Pages : 249-259
- DOI
  10.1016/j.numecd.2016.11.008
- Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H07067, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-26463136, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11551
[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice exhibit uncoupling protein 1 upregulation in adipose tissues following chronic cold exposure2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
- Journal Title
  
  J Oral Biosci
  
  Volume : 印刷中 Pages : 108-112
- DOI
  10.1016/j.job.2017.04.001
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation2017
- Author(s)
  Yamawaki Y, Oue K, Shirawachi S, Asano S, Harada K, Kanematsu T.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume : 53（1） Pages : 18-24
- DOI
  10.1016/j.jdsr.2016.06.001
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-16K11503
[Journal Article] Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by β-Adrenergic2016
- Author(s)
  Oue K, Zhang J, Harada-Hada K, Asano S, Yamawaki Y, Hayashiuchi M, Furusho H, Takata T, Irifune M, Hirata M, Kanematsu T.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume : 291 Pages : 185-96
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-24229009
[Journal Article] Phospholipase C-related catalytically inactive protein participates in the autophagic elimination of staphylococcus aureus Infecting mouse embryonic fibroblasts.2014
- Author(s)
  Harada-Hada K, Harada K, Kato F, Hisatsune J, Tanida I, Ogawa M, Asano S, Sugai M, Hirata M, Kanematsu T.
- Journal Title
  
  PLoS One
  
  Volume : 9
- DOI
  10.1371/journal.pone.0098285
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460533, KAKENHI-PROJECT-25860321, KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009
[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase.2014
- Author(s)
  T. Okumura, K. Harada, K. Oue, J. Zhang, S. Asano, M. Hayashiuchi, A. Mizokami, H. Tanaka, M. Irifune, N. Kamata, M. Hirata, and T. Kanematsu.
- Journal Title
  
  PLoS ONE
  
  Volume : 9
- DOI
  10.1371/journal.pone.0100559
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-26861553, KAKENHI-PROJECT-24229009
[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion.2014
- Author(s)
  Satoshi Asano, Tomomi Nemoto, Tomoya Kitayama, Kae Harada, Jun Zhang, Kana Harada, Isei Tanida, Masato Hirata, and Takashi, Kanematsu
- Journal Title
  
  Biol. Open.
  
  Volume : 3 Pages : 463-474
- DOI
  10.1242/bio.20147591
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22113005, KAKENHI-PROJECT-25861756, KAKENHI-PROJECT-25861757, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009
[Presentation] Phospholipase C-related catalytically inactive protein protects PI(4,5)P2 from its metabolic enzyme and contributes to completion of cytokinesis2018
- Author(s)
  Yasuka Ikura, Satoshi Asano, Takashi Kanematsu
- Organizer
  7th Hiroshima Conference on Education and Science in Dentistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  Asano S, Kanematsu T
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Over expression of PRIP in MCF-7 cells, a breast cancer cell line, enhances cisplatin induced apoptosis2017
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第50回広島大学歯学会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Regulation of cytokinesis by phospholipase C-related catalytically inactive protein, as a sequestrant of PI(4,5)P2 in the cleavage furrow2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] PRIP発現は癌細胞転移を抑制する2017
- Author(s)
  浅野智志、兼松隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Over expression of PRIP in MCF-7 cells, a breast cancer cell line, enhances cisplatin induced apoptosis2017
- Author(s)
  Yuka Maetani, Satoshi Asano, Masahiro Irifune, Takashi Kanematsu
- Organizer
  第50回広島大学歯学会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Expression of phospholipase C-related catalytically inactive protein suppresses cancerous metastasis2017
- Author(s)
  浅野智志、兼松隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] The mechanism of phospholipase C-related catalytically inactive protein (PRIP)-mediated energy metabolism by β-adrenergic stimulation in brown adipocytes2017
- Author(s)
  大植香菜，山脇洋輔，浅野智志，入舩正浩，兼松隆
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Regulation of cytokinesis by phospholipase C-related catalytically inactive protein, as a sequestrant of PI(4,5)P2 in the cleavage furrow2017
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11644
[Presentation] Suppression of PI3K-dependent breast cancer cell migration by PRIP2016
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  GAP (Global Academic Program) related meeting
- Place of Presentation
  Hiroshima
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Suppression of PI3K-dependent breast cancer cell migration by PRIP2016
- Author(s)
  浅野智志、兼松隆
- Organizer
  GAP (Global Academic Program) related meeting
- Place of Presentation
  広島大学（広島県・広島市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Tumor cell migration is regulated by PRIP-mediated phosphatidylinositol turnover2016
- Author(s)
  浅野智志、兼松隆
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] PRIP分子による細胞移動の調節PRIPは細胞膜におけるPI(3,4,5)P3合成を調節している2015
- Author(s)
  浅野智志、兼松隆
- Organizer
  第56回日本生化学会中国・四国支部例会
- Place of Presentation
  島根大学（島根県・松江市）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Suppression of breast cancer cell migration by PRIP, an upstream regulator of phosphoinositide 3-kinase signaling pathway2015
- Author(s)
  浅野智志、兼松隆
- Organizer
  第48回広島大学歯学会総会
- Place of Presentation
  広島大学（広島県・広島市）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-15K20372
[Presentation] Regulation of insulin secretion by phospholipase C-related catalytically inactive protein2013
- Author(s)
  浅野智志
- Organizer
  第55回歯科基礎医学会学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of second phase of insulin secretion by phospholipase C-related catalytically inactive protein2013
- Author(s)
  浅野智志
- Organizer
  46th meeting of the Hiroshima University Dental Society
- Place of Presentation
  広島大学
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Phospholipase C-related catalytically inactive protein modulates insulin secretory vesicle movement2013
- Author(s)
  浅野智志
- Organizer
  第５回広島カンファレンス
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of cell migration by phospholipase C-related catalytically inactive protein
- Author(s)
  S. Asano, and T. Kanematsu.
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25861756
[Presentation] Regulation of cell migration by PRIP: PRIP protects PI(4,5)P2 and decreases PDGF-induced PI(3,4,5)P3 synthesis in the plasma membrane
- Author(s)
  Satoshi Asano, Takashi Kanematsu
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25861756

1. Kanematsu Takashi (10264053)

# of Collaborated Projects : 3results

# of Collaborated Products : 20results
2. YAMAWAKI YOSUKE (90584061)

# of Collaborated Projects : 2results

# of Collaborated Products : 6results
3. HARADA KAE (60432663)

# of Collaborated Projects : 1results

# of Collaborated Products : 7results
4. OUE KANA

# of Collaborated Projects : 1results

# of Collaborated Products : 6results
5. Terukazu Sanui

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
6. 相澤秀紀

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 伊藤日加瑠

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 菅井基行

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. 久恒順三

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 平田雅人

# of Collaborated Projects : 0results

# of Collaborated Products : 5results
11. 溝上顕子

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
12. 入舩正浩

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
13. 高靖

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 竹内弘

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
15. 根本知己

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
16. 佐藤俊一

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
17. 佐野朋美

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
18. 西村英紀

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
19. 櫛山曉史

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
20. 鈴木茂樹

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

ASANO Satoshi 浅野 智志

Research Projects

Research Products

Co-Researchers

PRIPの新奇癌細胞制御機構に着目した抗腫瘍薬開発研究Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

膜リン脂質代謝変調がもたらす癌増悪メカニズムの解明研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studied on the mechanisms of cancer metastasis and proliferation regulated by a new moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of blood clotting and venous repair regulated by a novel proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice exhibit uncoupling protein 1 upregulation in adipose tissues following chronic cold exposure2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by β-Adrenergic2016

Author(s)

Journal Title

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein participates in the autophagic elimination of staphylococcus aureus Infecting mouse embryonic fibroblasts.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion.2014

Author(s)

ASANO Satoshi 浅野智志