MIYASHITA Keiichi 宮下圭一

Researcher Number	30585063
Other IDs
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Affiliation (Current)	2025: 鹿児島大学, 医歯学域鹿児島大学病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 鹿児島大学, 医歯学域鹿児島大学病院, 助教 2016 – 2018: 鹿児島大学, 医歯学域附属病院, 助教 2015: 鹿児島大学, 医歯学域医学部・歯学部附属病院, 助教 2010 – 2014: 鹿児島大学, 医学部・歯学部附属病院, 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator Th1/Th2 / IFN-γ / IL-4 / OVA(Ovalbmin) / PC(Phosphorylcholine) / NTHi / PAFR / NALT / bovine serum albumin / ovalbumin … More / Ag-presenting cells / dendritic cells / Phosphorylcholine / アレルギー / Phosphprylcholine / Th1/Th2バランス / 粘膜ワクチン … More Except Principal Investigator 粘膜免疫 / 粘膜ワクチン / 経鼻免疫 / ホスホリルコリン / 経鼻ワクチン / 舌下免疫 / ワクチン / 粘膜免疫応答 / 経皮免疫 / PspA / アジュバント / 肺炎球菌 / アレルギー / アレルギー性鼻炎 / 特異的IgA / 感染防御 / 免疫強化 / 分泌型IgA / IgA / 鼻腔投与 / Poly(I:C) / streptococcus pneumoniae / 経眼投与 / P6 / 結合型ホスホリルコリン / 結合型ホスホリルコリ重合体（R-MPC） / 細菌接着性 / 結合型ホスホリルコリン重合体 / IgE / ハプテン作用 / アジュバント作用 / Th１/Th２型免疫応答 / 粘膜アジュバント / 広域スペクトラム / Th1/Th2型免疫応答 / ホスホリルコリン重合体 / 鼻咽腔関連リンパ組織 / インフルエンザ / 血小板活性化因子受容体 / ブースター効果 / 二相作用 / インフルエンザ菌 / 抗PC抗体 / バイオフィルム / 細菌接着 / 抗炎症作用 / IgA腎症 / 感染症 / ﾏｲｸﾛニードル / 経皮ワクチン / PC-KLH / Phoshorylcholine(PC) / 特異的抗体価 / ｺﾚﾗﾄｷｼﾝ / ﾎｽﾎﾘﾙｺﾘﾝ / コレラトキシン Less

Heterologous prime boost strategyを利用した粘膜免疫を誘導するワクチンの開発
- Principal Investigator
  
  大堀純一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
Intranasolacrimal immunization for induction of secretory IgA responses in the respiratory tract.
- Principal Investigator
  
  永野広海
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
Development of a wide-spectrum vaccine using a new mucosal adjuvant
- Principal Investigator
  
  Kurono Yuichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kagoshima University
Development of a novel mucosal vaccine applying the immune memory function of nasopharyngeal-related lymphoid tissue (NALT)
- Principal Investigator
  
  OHORI Junichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Transcutaneous immunization with phosphorylcholine induces antigen-specific mucosal and systemic immune responses
- Principal Investigator
  
  Nagano Hiromi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Development of novel mucosal vaccine by applying the biphasic reaction of phosphorylcholine
- Principal Investigator
  
  Kurono Yuichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Application of phosphorylcholine for multi-functional mucosal vaccine
- Principal Investigator
  
  KURONO YUICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Phosphorylcholine Suppresses the AllergicRhinitis inMicePrincipal Investigator
- Principal Investigator
  
  MIYASHITA Keiichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University
Transcutaneous immunization induces antigen specific mucosal and syatemic immune responses in mice
- Principal Investigator
  
  MASEDA Yoshiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kagoshima University

All 2018 2017 2013 Other

All Journal Article Presentation

[Journal Article] Mucosal and systemic immune response to sublingual or intranasal immunization with phosphorylcholine2018
- Author(s)
  Maseda Yoshiko、Ohori Junichiro、Tanaka Norimitsu、Nagano Hiromi、Miyashita Keiichi、Kurono Yuichi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 45 Issue: 2 Pages: 273-280
- DOI
  10.1016/j.anl.2017.04.009
- NAID
  130007589878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11239
[Journal Article] Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice2018
- Author(s)
  Keiichi Miyashita,MD, Junichiro Ohori,MD,PhD, Hiromi Nagano, MD, Satoshi Fukuyama,MD, PhD, Yuichi Kurono, MD,PhD
- Journal Title
  
  The Laryngoscope
  
  Volume: 128(7) Issue: 7
- DOI
  10.1002/lary.27030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11239
[Journal Article] Transcutaneous immunization in auricle skin induces antigen-specific mucosal and systemic immune responses in BALB/c mice2017
- Author(s)
  Nagano H., Jimura T., Nagano M., Miyashita K., Kurono Y.
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 44 Issue: 4 Pages: 411-416
- DOI
  10.1016/j.anl.2016.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11238, KAKENHI-PROJECT-16K11239
[Presentation] Phosphorylcholine suppresses the allergic rhinitis in mice2013
- Author(s)
  K. Miyashita
- Organizer
  第４２回日本免疫学会学術集会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] Phosphorylcholine経鼻投与によるアレルギー反応抑制効果
- Author(s)
  宮下圭一
- Organizer
  第33回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  東京(東武ホテルレバント東京)
- Year and Date
  2015-02-26 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-25462689
[Presentation] Phosphorylcholine suppressed the allergic rhinitis in mice.
- Author(s)
  Keiichi Miyashita
- Organizer
  25th Congress of the European Rhinology Society in conjunction with 32th International Symposium of Infection & Allergy of the Nose
- Place of Presentation
  Amsterdam, The Netherlands
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-25462689

1. NAGANO Hiromi (60613148)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. KURONO Yuichi (80153427)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. OHORI Junichiro (90507162)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
4. MAKISE Takao (30585120)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KAWABATA MASAKI (30585112)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 地村友宏 (10709596)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. MASEDA Yoshiko (70535666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 井内寛之 (90645285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 山下勝 (10635519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 田淵みな子 (90838187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. MATSUNE Shoji (00253899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原田みずえ (20585103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 宮之原郁代 (40305131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYASHITA Keiichi 宮下 圭一

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Phosphorylcholine Suppresses the AllergicRhinitis inMicePrincipal Investigator

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[Journal Article] Mucosal and systemic immune response to sublingual or intranasal immunization with phosphorylcholine2018

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[Journal Article] Intranasal immunization with phosphorylcholine suppresses allergic rhinitis in mice2018

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[Journal Article] Transcutaneous immunization in auricle skin induces antigen-specific mucosal and systemic immune responses in BALB/c mice2017

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[Presentation] Phosphorylcholine suppresses the allergic rhinitis in mice2013

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[Presentation] Phosphorylcholine経鼻投与によるアレルギー反応抑制効果

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[Presentation] Phosphorylcholine suppressed the allergic rhinitis in mice.

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MIYASHITA Keiichi 宮下圭一