Toyota Tomoko 豊田知子

… Alternative Names

豊田知子トヨタトモコ

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Researcher Number	30596432
Other IDs
Affiliation (Current)	2023: 産業医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 医学部, 助教 2019 – 2021: 産業医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 52020:Neurology-related
Keywords	Principal Investigator mTOR / 進行性ミオクローヌスてんかん / フラボノール / オートファジー / 神経変性 / てんかん / ポリグルタミン病 / 歯状核赤核淡蒼球ルイ体萎縮症 Except Principal Investigator 凝集体形成抑制 / 病因蛋白質の選択的な分解 … More / オートファジー / 運動ニューロン疾患 / 神経変性 / 毒性軽減 / 分子シャペロン / HIKESHI / 歯状核赤核淡蒼球ルイ体萎縮症 / 球脊髄性筋萎縮症 / ポリグルタミン病 Less

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseases
- Principal Investigator
  
  足立弘明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
The development of disease- modifying therapies for progressive myoclonus epilepsyPrincipal Investigator
- Principal Investigator
  
  豊田知子
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenarative diseases
- Principal Investigator
  
  Adachi Hiroaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Complete sequencing of expanded SAMD12 repeats by long-read sequencing with Cas9-mediated enrichment.2021
- Author(s)
  Mizuguchi T, Toyota T, Miyatake S, Mitsuhashi S, Doi H, Kudo Y, Kishida H, Hayashi N, Tusburaya RS, Kinoshita M, Fukuyama T, Fukuda H, Koshimizu E, Tsuchida N, Uchiyama Y, Fujita A, Takata A, Miyake N, Kato M, Tanaka F, Adachi H, Matsumoto N.
- Journal Title
  
  Brain
  
  Volume: 144 Issue: 4 Pages: 1103-1117
- DOI
  10.1093/brain/awab021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970, KAKENHI-PLANNED-20H05777, KAKENHI-PROJECT-19H03621, KAKENHI-PROJECT-21H02855, KAKENHI-PROJECT-20K07907, KAKENHI-PROJECT-20K08164, KAKENHI-PROJECT-20K08236, KAKENHI-PROJECT-21K07298, KAKENHI-PROJECT-21K15704
[Journal Article] Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis2020
- Author(s)
  Masaki Hiromi、Watanabe Keita、Kakeda Shingo、Ide Satoru、Sugimoto Kohichiro、Ueda Issei、Hamamura Toshihiko、Hisanaga Sachi、Toyota Tomoko、Akamatsu Naoki、Shimajiri Shohei、Yamamoto Junkoh、Nishizawa Shigeru、Adachi Hiroaki、Korogi Yukunori
- Journal Title
  
  Japanese Journal of Radiology
  
  Volume: 38 Issue: 11 Pages: 1020-1027
- DOI
  10.1007/s11604-020-01019-y
- NAID
  50014626761
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07970
[Journal Article] Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads2019
- Author(s)
  Satomi Mitsuhashi, Martin C. Frith, Takeshi Mizuguchi, Satoko Miyatake, Tomoko Toyota, Hiroaki Adachi, Yoko Oma, Yoshihiro Kino, Hiroaki Mitsuhashi, Naomichi Matsumoto
- Journal Title
  
  Genome Biology
  
  Volume: 20 Issue: 1 Pages: 58-58
- DOI
  10.1186/s13059-019-1667-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09683, KAKENHI-PROJECT-17K10080, KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-19K07970
[Journal Article] Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases2018
- Author(s)
  Mizuguchi Takeshi、Toyota Tomoko、Adachi Hiroaki、Miyake Noriko、Matsumoto Naomichi、Miyatake Satoko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 3 Pages: 191-197
- DOI
  10.1038/s10038-018-0551-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PUBLICLY-17H05708, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-19K07970
[Presentation] Perampanel improves the epilepsy phenotype by the phosphorylation of GluA1 in the DRPLA transgenic mice2021
- Author(s)
  豊田知子、黄哲、岡田和将、佐藤俊哉、辻省二、足立弘明
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K15704
[Presentation] Perampanel improves the epilepsy phenotype by the phosphorylation of GluA1 in the DRPLA transgenic mice2021
- Author(s)
  Tomoko Toyota, Zhe Huang, Kazumasa Okada, Toshiya Sato, Shoji Tsuji, Hiroaki Adachi
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] TFEB over-expression reduces mutant AR protein and ameliorates phenotypes of the SBMA transgenic mouse model2021
- Author(s)
  Hiroaki Adachi, Zhe Huang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Effects of the overexpression of TFEB in cellular and mouse models of spinal and bulbar muscular atrophy2020
- Author(s)
  Hiroaki Adachi, Zhe Huang, Qiang Qiang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Effects of the overexpression of TFEB in cellullar and mouse models of neurodegenerarive diseases.2020
- Author(s)
  Hiroaki Adachi, Zhe Huang, Qiang Qiang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota, Yukio Iwanaka
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 and TRAPPC9 implicates autophagosome-lysosome fusion defects in the pathogenesis of neurodegenerative diseases.2019
- Author(s)
  Hiroaki Adachi, Zhe Huang, Kazumasa Okada, Keiko Ohnari, Tomoyo Hashimoto, Tomoko Toyota
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 implicates autophagosome-lysosome fusion defects in the neurodegenerative diseases.2019
- Author(s)
  足立弘明, 黄哲, 岡田和将, 大成圭子, 橋本智代, 豊田知子, 岩中行己男
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Dynactin-1 and TRAPPC9 implicate autophagosome-lysosome fusion in the pathogenesis of neurodegenerative diseases.2019
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanaka Y.
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07970
[Presentation] Perampanel administration to the Q129 and Q113 DRPLA transgenic mice.2019
- Author(s)
  Toyota T, Huang Z, Okada K, Sato T, Tsuji S, Adachi H.
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07970

1. Adachi Hiroaki (40432257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 黄哲 (30745112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KINO Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toyota Tomoko 豊田 知子

豊田 知子 トヨタ トモコ

Research Projects

Research Products

Co-Researchers

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of disease- modifying therapies for progressive myoclonus epilepsyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenarative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Complete sequencing of expanded SAMD12 repeats by long-read sequencing with Cas9-mediated enrichment.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hippocampal sclerosis without visually detectable hippocampal MRI abnormalities: automated subfield volumetric analysis2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Perampanel improves the epilepsy phenotype by the phosphorylation of GluA1 in the DRPLA transgenic mice2021

Author(s)

Organizer

Data Source

[Presentation] Perampanel improves the epilepsy phenotype by the phosphorylation of GluA1 in the DRPLA transgenic mice2021

Author(s)

Organizer

Data Source

[Presentation] TFEB over-expression reduces mutant AR protein and ameliorates phenotypes of the SBMA transgenic mouse model2021

Author(s)

Organizer

Data Source

[Presentation] Effects of the overexpression of TFEB in cellular and mouse models of spinal and bulbar muscular atrophy2020

Author(s)

Organizer

Data Source

[Presentation] Effects of the overexpression of TFEB in cellullar and mouse models of neurodegenerarive diseases.2020

Author(s)

Organizer

Data Source

[Presentation] Dynactin-1 and TRAPPC9 implicates autophagosome-lysosome fusion defects in the pathogenesis of neurodegenerative diseases.2019

Author(s)

Organizer

Data Source

[Presentation] Dynactin-1 implicates autophagosome-lysosome fusion defects in the neurodegenerative diseases.2019

Author(s)

Organizer

Data Source

[Presentation] Dynactin-1 and TRAPPC9 implicate autophagosome-lysosome fusion in the pathogenesis of neurodegenerative diseases.2019

Author(s)

Organizer

Data Source

[Presentation] Perampanel administration to the Q129 and Q113 DRPLA transgenic mice.2019

Author(s)

Organizer

Data Source

Toyota Tomoko 豊田知子

豊田知子トヨタトモコ