Huang Zhe 黄哲

… Alternative Names

黄哲コウテツ

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Researcher Number	30745112
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 産業医科大学, 医学部, 助教 2020 – 2022: 名古屋大学, 医学系研究科, 特任講師 2015 – 2016: 産業医科大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 52010:General internal medicine-related / Medium-sized Section 52:General internal medicine and related fields / Neurology
Keywords	Except Principal Investigator サルコペニア / オートファジー / 凝集体形成抑制 / 病因蛋白質の選択的な分解 / 運動ニューロン疾患 / 神経変性 / カテプシン / 悪性腫瘍 / カテブシン / カテプシンK … More / 悪液質 / マウス / 老化制御 / エクソゾーム / 細胞治療 / 間葉系幹細胞 / 老化 / ユビキチンｰプロテアソーム系 / 筋萎縮性側索硬化症 / 球脊髄性筋萎縮症 / ポリグルタミン病 / HIKESHI / TFEB / ユビキチン・プロテアソーム系 / 分子シャペロン / 神経変性疾患 Less

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseases
- Principal Investigator
  
  足立弘明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Research on mesenchymal stem cells and their exosomes as aging regulators
- Principal Investigator
  
  Kuzuya Masafumi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nagoya University
Research on cathepsin K as a new target for treatment of sarcopenia associated with cachexia
- Principal Investigator
  
  葛谷雅文
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Nagoya University
Selective protein degradation with the aim of developing therapies for neurodegenarative diseases
- Principal Investigator
  
  Adachi Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2024 2023 2022 2021 2020 2016

All Journal Article Presentation Patent

[Journal Article] CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer’s disease.2024
- Author(s)
  Qiang Q, Skudder-Hill L, Toyota T, Huang Z, Wei W, Adachi H.
- Journal Title
  
  J Neurol Sci
  
  Volume: 457 Pages: 122861-122861
- DOI
  10.1016/j.jns.2023.122861
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06976
[Journal Article] Cathepsin K activity controls cachexia-induced muscle atrophy via the modulation of IRS1 ubiquitination.2022
- Author(s)
  Meng X, Huang Z, Inoue A, Wang H, Wan Y, Yue X, Xu S, Jin X, Shi GP, Kuzuya M, Cheng XW.
- Journal Title
  
  J Cachexia Sarcopenia Muscle.
  
  Volume: 13(2) Issue: 2 Pages: 1197-1209
- DOI
  10.1002/jcsm.12919
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03574
[Journal Article] Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation2016
- Author(s)
  Huang Z, Adachi H.
- Journal Title
  
  Journal of UOEH
  
  Volume: 38 Issue: 2 Pages: 139-148
- DOI
  10.7888/juoeh.38.139
- NAID
  130005157739
- ISSN
  0387-821X, 2187-2864
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293207
[Patent] 筋肉量の低下抑制に用いる細胞調製物2020
- Inventor(s)
  成憲武、黄哲、朴麗梅、葛谷雅文、原田雅充
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K21572
[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023
- Author(s)
  足立弘明、黄哲、豊田知子、勝野雅央、祖父江元
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06976
[Presentation] 神経変性疾患の病因蛋白質の分解亢進による予防2023
- Author(s)
  足立弘明、黄哲、豊田知子
- Organizer
  第5回日本脳サプリメント学会
- Data Source
  KAKENHI-PROJECT-23K06976
[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023
- Author(s)
  足立弘明、黄哲、豊田知子、勝野雅央、祖父江元
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K06976
[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023
- Author(s)
  Adachi H, Huang Z, Toyota T, Qiang Q, Katsuno M, Sobue G
- Organizer
  Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06976
[Presentation] ヒト臍帯由来間葉系幹細胞を用いたサルコペニア治療の可能性2021
- Author(s)
  黄　哲
- Organizer
  第８回日本サルコペニア・フレイル学会大会
- Data Source
  KAKENHI-PROJECT-20K21572
[Presentation] オートファジーによる変異アンドロゲン受容体の分解とその治療への応用2016
- Author(s)
  足立弘明、黄哲、岡田和将、大成圭子、橋本智代、岩中行己男、豊田知子、勝又竜
- Organizer
  第11回　臨床ストレス応答学会大会
- Place of Presentation
  山口大学（山口県・山口市）
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] TFEB and Hikeshi influence the degradation of the disease-causative proteins in cellular models of neurodegenerative diseases.2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y, Sobue G.
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego（米国）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-26293207
[Presentation] Effects of the overexpression of TFEB in cellular models of neurodegenerative diseases2016
- Author(s)
  Adachi H, Huang Z, Okada K, Ohnari K, Hashimoto T, Toyota T, Iwanakan Y
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26293207

1. Adachi Hiroaki (40432257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Kuzuya Masafumi (10283441)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 朴麗梅 (60867208)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 岡田和将 (30341499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 岩中行己男 (60590461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 橋本智代 (70425685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 豊田知子 (30596432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Huang Zhe 黄 哲

黄 哲 コウ テツ

Research Projects

Research Products

Co-Researchers

Reducing toxicity of disease-causative molecules with the aim of developing therapies for neurodegenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on mesenchymal stem cells and their exosomes as aging regulators

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on cathepsin K as a new target for treatment of sarcopenia associated with cachexia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Selective protein degradation with the aim of developing therapies for neurodegenarative diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CSF 14-3-3 zeta(ζ) isoform is associated with tau pathology and cognitive decline in Alzheimer’s disease.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cathepsin K activity controls cachexia-induced muscle atrophy via the modulation of IRS1 ubiquitination.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Patent] 筋肉量の低下抑制に用いる細胞調製物2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

Author(s)

Organizer

Data Source

[Presentation] 神経変性疾患の病因蛋白質の分解亢進による予防2023

Author(s)

Organizer

Data Source

[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

Author(s)

Organizer

Data Source

[Presentation] Kaempferol promotes the degradation of mutant proteins via a novel mTOR-dependent autophagic pathway2023

Author(s)

Organizer

Data Source

[Presentation] ヒト臍帯由来間葉系幹細胞を用いたサルコペニア治療の可能性2021

Author(s)

Organizer

Data Source

[Presentation] オートファジーによる変異アンドロゲン受容体の分解とその治療への応用2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] TFEB and Hikeshi influence the degradation of the disease-causative proteins in cellular models of neurodegenerative diseases.2016

Huang Zhe 黄哲

黄哲コウテツ