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Ono Chikako  小野 慎子

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ONO Chikako  小野 慎子

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Researcher Number 30626437
Other IDs
Affiliation (Current) 2022: 大阪大学, 感染症総合教育研究拠点, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2022: 大阪大学, 感染症総合教育研究拠点, 特任准教授(常勤)
2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員
2019 – 2020: 大阪大学, 微生物病研究所, 助教
2018: 大阪大学, 微生物病研究所, 特任助教(常勤)
2014 – 2016: 大阪大学, 微生物病研究所, 特任研究員(常勤)
2012 – 2013: 大阪大学, 微生物病研究所, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 49060:Virology-related / Laboratory animal science / Virology
Except Principal Investigator
Basic Section 49060:Virology-related
Keywords
Principal Investigator
C型肝炎ウイルス / 感染症 / 肝外病変 / マイクロRNA / miRNA / マウスモデル / 癌 / HCV / SARS-CoV-2
Except Principal Investigator
リバースジェネティクス / SARS-CoV-2 / フラビウイルス / 新興再興感染症
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (12 People)
  •  Promotion of emerging and re-emerging virus research using high-speed reverse genetics

    • Principal Investigator
      福原 崇介
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Hokkaido University
  •  SARS-CoV-2増殖におけるマイクロRNAの機能解析Principal Investigator

    • Principal Investigator
      小野 慎子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Mechanistic analysis of persistent infection of HCV in non-hepatic cellsPrincipal Investigator

    • Principal Investigator
      Ono Chikako
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Osaka University
  •  Characterization of adapted HCV that can replicate efficiently in non-hepatic cellsPrincipal Investigator

    • Principal Investigator
      Ono Chikako
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Osaka University
  •  Establishment of mouse infection model of HCVPrincipal Investigator

    • Principal Investigator
      ONO Chikako
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University

All 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] Various miRNAs compensate the role of miR-122 on HCV replication.2020

    • Author(s)
      Ono C, Fukuhara T, Li S, Wang J, Sato A, Izumi T, Fauzyah Y, Yamamoto T, Morioka Y, Dokholyan NV, Standley DM, Matsuura Y.A3:J3
    • Journal Title

      PLoS Pathogens

      Volume: 16

    • DOI

      10.1371/journal.ppat.1008308

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-18K07146
  • [Journal Article] USP15 participates in HCV propagation through the regulation of viral RNA translation and lipid droplet formation.2019

    • Author(s)
      Kusakabe S、Suzuki T、Sugiyama Y、Haga S、Horike K、Tokunaga M、Hirano J、Zhang H、Chen DV、Ishiga H、Komoda Y、Ono C、Fukuhara T、Yamamoto M、Ikawa M、Satoh T、Akira S、Tanaka T、Moriishi Ki、Fukai M、Taketomi A、Yoshio S、Kanto T、Suzuki T、Okamoto T、Matsuura Y
    • Journal Title

      J Virol.

      Volume: 93 Pages: 1708-1718

    • DOI

      10.1128/jvi.01708-18

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-18H02661, KAKENHI-PLANNED-16H06432, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-19H03479
  • [Journal Article] Induction of selective autophagy in cells replicating hepatitis C virus genome.2018

    • Author(s)
      Mori Hiroyuki、Fukuhara Takasuke、Ono Chikako、Tamura Tomokazu、Sato Asuka、Fauzyah Yuzy、Wada Masami、Okamoto Toru、Noda Takeshi、Yoshimori Tamotsu、Matsuura Yoshiharu
    • Journal Title

      J. Gen. Virol.

      Volume: 99 Pages: 1643-1657

    • DOI

      10.1099/jgv.0.001161

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07146, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-26251020, KAKENHI-PROJECT-16J02628
  • [Journal Article] Characterization of miR-122-independent propagation of HCV2017

    • Author(s)
      C. Ono, T. Fukuhara, D. Motooka, S. Nakamura, D. Okuzaki, S. Yamamoto, T. Tamura, H. Mori, A. Sato, K. Uemura, Y. Fauzyah, T. Kurihara, T. Suda, A. Nishio, Su Su Hmwe, T. Okamoto, T. Tatsumi, T. Takehara, K. Chayama, T. Wakita, K. Koike, Y. Matsuura
    • Journal Title

      PLOS Pathogens

      Volume: -

    • DOI

      10.1371/journal.ppat.1006374

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19110, KAKENHI-PROJECT-17K09447, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-16J02628
  • [Journal Article] Human Cathelicidin Compensates for the Role of Apolipoproteins in Hepatitis C Virus Infectious Particle Formation2016

    • Author(s)
      Puig-Basagoiti F., Fukuhara T., Tamura T., Ono C., Uemura K., Kawachi Y., Yamamoto S., Mori H., Kurihara T., Okamoto T., Aizaki H., Matsuura Y.
    • Journal Title

      Journal of Virology

      Volume: 90 Pages: 1-14

    • DOI

      10.1128/jvi.00471-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01261, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15K19110
  • [Journal Article] Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus.2015

    • Author(s)
      Fukuhara T, Ono C, Puig-Basagoiti F, Matsuura Y
    • Journal Title

      Trends in Microbiology

      Volume: 23 Pages: 618-629

    • DOI

      10.1016/j.tim.2015.07.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19110, KAKENHI-PUBLICLY-15H01261, KAKENHI-PROJECT-25460566
  • [Journal Article] Immune Response Induced by Baculovirus Attenuates Transgene Expression in Mammalian Cells.2014

    • Author(s)
      Ono C., Ninomiya A., Yamamoto S., Abe T., Wen X., Fukuhara T., Sasai M., Yamamoto M., Saitoh T., Satoh T., Kawai T., Ishii J. K., Akira S., Okamoto T., and Matsuura Y.
    • Journal Title

      J Virol.

      Volume: 88 Pages: 2157-2167

    • DOI

      10.1128/jvi.03055-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24700429, KAKENHI-PROJECT-24890106, KAKENHI-PUBLICLY-25115511, KAKENHI-PUBLICLY-25117717, KAKENHI-PROJECT-25670027
  • [Journal Article] Novel permissive cell lines for a complete propagation of hepatitis C virus.2014

    • Author(s)
      Shiokawa M, Fukuhara T, Ono C, Yamamoto S, Okamoto T, Watanabe N, Wakita T, Matsuura Y.
    • Journal Title

      Journal of Virology

      Volume: 88(10) Pages: 5578-5594

    • DOI

      10.1128/jvi.03839-13

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24700429, KAKENHI-PUBLICLY-25115511
  • [Journal Article] Amphipathic α-Helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.2014

    • Author(s)
      Fukuhara T, Wada M, Nakamura S, Ono C, Shiokawa M, Yamamoto S, Motomura T, Okamoto T, Okuzaki D, Yamamoto M, Saito I, Wakita T, Koike K, Matsuura Y
    • Journal Title

      PLoS Pathogen

      Volume: 10(12)

    • DOI

      10.1371/journal.ppat.1004534

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-24700429, KAKENHI-PUBLICLY-25115511, KAKENHI-PROJECT-25460566, KAKENHI-PROJECT-26670221
  • [Presentation] Characterization of mutation in the 5’UTR of HCV in miR-122-dependent propagation2019

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Yuzy Fauzyah, Shiho Torii, Asuka Sato, Takuma Izumi, Takuya Yamamoto, Yuhei Morioka, and Yoshiharu Matsuura
    • Organizer
      第67回日本ウイルス学会
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] Involvement of various miRNAs for an efficient replication of HCV2019

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Yuzy Fauzyah, Shiho Torii, Asuka Sato, Takuma Izumi, Takuya Yamamoto, Yuhei Morioka, and Yoshiharu Matsuura
    • Organizer
      24th International Symposium on Heepatitis C Virus and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] Involvement of various miRNAs for an efficient replication of HCV2019

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Takuma Izumi, Yuzy Fauzyah, Toru Okamoto, and Yoshiharu Matsuura
    • Organizer
      The 18th Awaji International Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] Involvement of various miRNAs for an efficient replication of HCV2019

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Takuma Izumi, Yuzy Fauzyah, Toru Okamoto, and Yoshiharu Matsuura
    • Organizer
      The 38th American Society of Virology 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] Identification of comparable miRNAs with miR-122 on the propagation of hepatitis C virus.2018

    • Author(s)
      Ono, C., Fukuhara, T., Tamura, T., Mori, H., Sato, A., Fauzyah, Y., Okamoto, T., Chayama, K., Koike, K. and Matsuura, Y.
    • Organizer
      第66回日本ウイルス学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] miRNAs comparable with miR-122 on the propagation of hepatitis C virus.2018

    • Author(s)
      Ono, C., Fukuhara, T., Okuzaki, D., Tamura, T., Mori, H., Sato, A., Fauzyah, Y., Okamoto, T., Koike, K. and Matsuura, Y.
    • Organizer
      The 25th International Symposium on Hepatitis C Virus and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07146
  • [Presentation] G28A mutation is necessary for an efficient propagation of HCV in miR-122 deficient condition2016

    • Author(s)
      小野慎子,福原崇介,元岡大祐,中村昇太,山本聡美,森寛行,上村健太朗,岡本徹,Su Su Hmwe,茶山一彰,脇田隆字,小池和彦,松浦善治
    • Organizer
      23rd International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-10-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19110
  • [Presentation] CHARACTERIZATION OF MIR-122-INDEPENDENT PROPAGATION OF HCV2016

    • Author(s)
      小野慎子,福原崇介,山本聡美,森寛行,上村健太朗,河内悠華子,岡本徹,Su Su Hmwe,脇田隆字,小池和彦,松浦善治
    • Organizer
      American Society for Virology 2016 Meeting
    • Place of Presentation
      Virginia Tech
    • Year and Date
      2016-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19110
  • [Presentation] G28A mutation facilitates an efficient propagation of HCV in miR-122-independent manner2016

    • Author(s)
      小野慎子,福原崇介,元岡大祐,中村昇太,山本聡美,森寛行,上村健太朗,岡本徹,Su Su Hmwe,茶山一彰,脇田隆字,小池和彦,松浦善治
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19110
  • [Presentation] Characterization of miR-122-independent propagation of HCV2015

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Satomi Yamamoto, Hiroyuki Mori, Toru Okamoto, Su Su Hmwe, Takaji Wakita, Kazuhiko Koike and Yoshiharu Matsuura
    • Organizer
      22nd International symposium on Hepatitis C and related viruses
    • Place of Presentation
      フランス、ストラスブール
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19110
  • [Presentation] Characterization of miR-122-independent propagation of HCV2015

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Satomi Yamamoto, Hiroyuki Mori, Toru Okamoto, Su Su Hmwe, Takaji Wakita, Kazuhiko Koike and Yoshiharu Matsuura
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-15K19110
  • [Presentation] Innate immuneresponse induced by baculovirus suppresses transgene expression.2013

    • Author(s)
      Ono C, Yamamoto S, Ninomiya A, Fukuhara T, Okamoto T, Abe T, Matsuura Y
    • Organizer
      American Society for Virology 32nd Annual Meeting
    • Place of Presentation
      ペンシルバニア(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] Propagation of HCV in the miR-122-knockout Huh7 cells.2013

    • Author(s)
      Ono C, Fukuhara T, Shiokawa M, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
    • Organizer
      International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      メルボルン(オーストラリア)
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] miR-122ノックアウトHuh7細胞におけるHCV増殖2013

    • Author(s)
      小野慎子、福原崇介、塩川 舞、山本聡美、和田真実、岡本 徹、奥崎大介、松浦善治
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] Characterization of HCV Propagation in miR-122 Knockout Cells

    • Author(s)
      Ono C, Fukuhara T, Shiokawa M, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
    • Organizer
      33rd American Society for Virology Annual Meeting
    • Place of Presentation
      コロラド(アメリカ合衆国)
    • Year and Date
      2014-06-21 – 2014-06-25
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] Characterization of HCV propagation in miR-122 knockout cells

    • Author(s)
      Ono C, Fukuhara T, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
    • Organizer
      第13回あわじしま感染症・免疫フォーラム
    • Place of Presentation
      奈良県新公会堂(奈良)
    • Year and Date
      2014-09-23 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] Establishment of mouse liver cell lines susceptible to hepatitis C virus infection

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Mai Shiokawa, Toru Okamoto, Yoshiharu Matsuura
    • Organizer
      The 11th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路夢舞台国際会議場( 兵庫)
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] C型肝炎ウイルスに感受性を示すマウス肝臓細胞株の樹立

    • Author(s)
      小野慎子、福原崇介、塩川 舞、岡本 徹、松浦善治
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      グランキューブ大阪( 大阪)
    • Data Source
      KAKENHI-PROJECT-24700429
  • [Presentation] C型肝炎ウイルスに感受性を示すマウス肝臓細胞株の樹立

    • Author(s)
      小野慎子、福原崇介、塩川 舞、岡本 徹、松浦善治
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      マリンメッセ福岡( 福岡)
    • Data Source
      KAKENHI-PROJECT-24700429
  • 1.  福原 崇介 (70598739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  津田 祥美 (70447051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SASAI Miwa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  SAITOH Tatsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  松浦 善治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 6.  吉森 保
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  脇田 隆字
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 8.  鈴木 信弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  鈴木 亮介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  鈴木 哲朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  小池 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  斎藤 泉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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