Ono Chikako 小野慎子

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ONO Chikako 小野慎子

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Researcher Number	30626437
Other IDs
Affiliation (Current)	2023: 大阪大学, 感染症総合教育研究拠点, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪大学, 感染症総合教育研究拠点, 特任准教授(常勤) 2019 – 2020: 大阪大学, 微生物病研究所, 助教 2018: 大阪大学, 微生物病研究所, 特任助教(常勤) 2014 – 2016: 大阪大学, 微生物病研究所, 特任研究員(常勤) 2012 – 2013: 大阪大学, 微生物病研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Virology / Laboratory animal science Except Principal Investigator Basic Section 49060:Virology-related
Keywords	Principal Investigator 感染症 / C型肝炎ウイルス / miRNA / マイクロRNA / 肝外病変 / SARS-CoV-2 / HCV / 癌 / マウスモデル Except Principal Investigator 新興再興感染症 … More / フラビウイルス / リバースジェネティクス / Imaging / レポーター / SARS-CoV-2 Less

Promotion of emerging and re-emerging virus research using high-speed reverse genetics
- Principal Investigator
  
  福原崇介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Hokkaido University
SARS-CoV-2増殖におけるマイクロRNAの機能解析Principal Investigator
- Principal Investigator
  
  小野慎子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka University
Mechanistic analysis of persistent infection of HCV in non-hepatic cellsPrincipal Investigator
- Principal Investigator
  
  Ono Chikako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka University
Characterization of adapted HCV that can replicate efficiently in non-hepatic cellsPrincipal Investigator
- Principal Investigator
  
  Ono Chikako
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Establishment of mouse infection model of HCVPrincipal Investigator
- Principal Investigator
  
  ONO Chikako
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity2021
- Author(s)
  Motozono Chihiro、Toyoda Mako、Zahradnik Jiri、Saito Akatsuki、Other 19 authors、Ikeda Terumasa、Nakagawa So、Ueno Takamasa、Sato Kei
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 29 Issue: 7 Pages: 1124-1136
- DOI
  10.1016/j.chom.2021.06.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06382, KAKENHI-PROJECT-19K07623, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-19J20488, KAKENHI-PROJECT-20K15767, KAKENHI-PROJECT-18KK0447
[Journal Article] Various miRNAs compensate the role of miR-122 on HCV replication.2020
- Author(s)
  Ono C, Fukuhara T, Li S, Wang J, Sato A, Izumi T, Fauzyah Y, Yamamoto T, Morioka Y, Dokholyan NV, Standley DM, Matsuura Y.A3:J3
- Journal Title
  
  PLoS Pathog
  
  Volume: 16 Issue: 6 Pages: e1008308-e1008308
- DOI
  10.1371/journal.ppat.1008308
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-18K07146, KAKENHI-ORGANIZER-16H06429
[Journal Article] USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation2019
- Author(s)
  Kusakabe S、Suzuki T、Sugiyama Y、Haga S、Horike K、Tokunaga M、Hirano J、Zhang H、Chen DV、Ishiga H、Komoda Y、Ono C、Fukuhara T、Yamamoto M、Ikawa M、Satoh T、Akira S、Tanaka T、Moriishi Ki、Fukai M、Taketomi A、Yoshio S、Kanto T、Suzuki T、Okamoto T、Matsuura Y
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 6 Pages: 1708-1718
- DOI
  10.1128/jvi.01708-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-18H02661, KAKENHI-PLANNED-16H06432, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-19H03479
[Journal Article] Induction of selective autophagy in cells replicating hepatitis C virus genome2018
- Author(s)
  Mori Hiroyuki、Fukuhara Takasuke、Ono Chikako、Tamura Tomokazu、Sato Asuka、Fauzyah Yuzy、Wada Masami、Okamoto Toru、Noda Takeshi、Yoshimori Tamotsu、Matsuura Yoshiharu
- Journal Title
  
  Journal of General Virology
  
  Volume: 99 Issue: 12 Pages: 1643-1657
- DOI
  10.1099/jgv.0.001161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07146, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-26251020, KAKENHI-PROJECT-16J02628
[Journal Article] Characterization of miR-122-independent propagation of HCV2017
- Author(s)
  C. Ono, T. Fukuhara, D. Motooka, S. Nakamura, D. Okuzaki, S. Yamamoto, T. Tamura, H. Mori, A. Sato, K. Uemura, Y. Fauzyah, T. Kurihara, T. Suda, A. Nishio, Su Su Hmwe, T. Okamoto, T. Tatsumi, T. Takehara, K. Chayama, T. Wakita, K. Koike, Y. Matsuura
- Journal Title
  
  PLoS Pathogens
  
  Volume: - Issue: 5 Pages: e1006374-e1006374
- DOI
  10.1371/journal.ppat.1006374
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K19110, KAKENHI-PROJECT-17K09447, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-16J02628
[Journal Article] Human cathelicidin compensates for the role of apolipoproteins in the infectious particle formation of HCV.2016
- Author(s)
  Puig-Basagoiti F., Fukuhara T., Tamura T., Ono C., Uemura K., Kawachi Y., Yamamoto S., Mori H., Kurihara T., Okamoto T., Aizaki H., Matsuura Y.
- Journal Title
  
  Journal of Virology
  
  Volume: 90 Issue: 19 Pages: 1-14
- DOI
  10.1128/jvi.00471-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01261, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15K19110
[Journal Article] Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus2015
- Author(s)
  Fukuhara T, Ono C, Puig-Basagoiti F, Matsuura Y
- Journal Title
  
  Trends in Microbiology
  
  Volume: 23 Issue: 10 Pages: 618-629
- DOI
  10.1016/j.tim.2015.07.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19110, KAKENHI-PUBLICLY-15H01261, KAKENHI-PROJECT-25460566
[Journal Article] Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.2014
- Author(s)
  Ono C., Ninomiya A., Yamamoto S., Abe T., Wen X., Fukuhara T., Sasai M., Yamamoto M., Saitoh T., Satoh T., Kawai T., Ishii J. K., Akira S., Okamoto T., and Matsuura Y.
- Journal Title
  
  Journal of Virology
  
  Volume: 88 Issue: 4 Pages: 2157-2167
- DOI
  10.1128/jvi.03055-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24700429, KAKENHI-PROJECT-24890106, KAKENHI-PUBLICLY-25115511, KAKENHI-PUBLICLY-25117717, KAKENHI-PROJECT-25670027
[Journal Article] Novel permissive cell lines for complete propagation of hepatitis C virus.2014
- Author(s)
  Shiokawa M, Fukuhara T, Ono C, Yamamoto S, Okamoto T, Watanabe N, Wakita T, Matsuura Y.
- Journal Title
  
  J Virol.
  
  Volume: 88(10) Issue: 10 Pages: 5578-94
- DOI
  10.1128/jvi.03839-13
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24700429, KAKENHI-PUBLICLY-25115511
[Journal Article] Amphipathic α-Helices in Apolipoproteins Are Crucial to the Formation of Infectious Hepatitis C Virus Particles2014
- Author(s)
  Fukuhara T, Wada M, Nakamura S, Ono C, Shiokawa M, Yamamoto S, Motomura T, Okamoto T, Okuzaki D, Yamamoto M, Saito I, Wakita T, Koike K, Matsuura Y
- Journal Title
  
  PLoS Pathog
  
  Volume: 10(12) Issue: 12 Pages: e1004534-e1004534
- DOI
  10.1371/journal.ppat.1004534
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-24700429, KAKENHI-PUBLICLY-25115511, KAKENHI-PROJECT-25460566, KAKENHI-PROJECT-26670221
[Presentation] C型肝炎ウイルスとマイクロ RNA2022
- Author(s)
  小野　慎子
- Organizer
  令和3年度「感染・免疫・がん・炎症」全国共同研究拠点シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07039
[Presentation] Characterization of mutation in the 5’UTR of HCV in miR-122-dependent propagation2021
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Shiho Torii, Itsuki Anzai, Rigel Suzuki, Yuzy Fauzyah, Yuhei Morioka, Yoshiharu Matsuura
- Organizer
  HCV2021 VIRTUAL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07039
[Presentation] SARS-CoV-2 の増殖における5’UTRのstem-loop構造の役割2021
- Author(s)
  Chikako Ono,Shiho Torii,Rahmi Deanty,Shuhei Taguwa,Yoshiaru Matsuura
- Organizer
  第68回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K07039
[Presentation] Characterization of mutation in the 5’UTR of HCV in miR-122-dependent propagation2019
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Yuzy Fauzyah, Shiho Torii, Asuka Sato, Takuma Izumi, Takuya Yamamoto, Yuhei Morioka, and Yoshiharu Matsuura
- Organizer
  第67回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] Involvement of various miRNAs for an efficient replication of HCV2019
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Yuzy Fauzyah, Shiho Torii, Asuka Sato, Takuma Izumi, Takuya Yamamoto, Yuhei Morioka, and Yoshiharu Matsuura
- Organizer
  24th International Symposium on Heepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] Involvement of various miRNAs for an efficient replication of HCV2019
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Takuma Izumi, Yuzy Fauzyah, Toru Okamoto, and Yoshiharu Matsuura
- Organizer
  The 18th Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] Involvement of various miRNAs for an efficient replication of HCV2019
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Takuma Izumi, Yuzy Fauzyah, Toru Okamoto, and Yoshiharu Matsuura
- Organizer
  The 38th American Society of Virology 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] Identification of comparable miRNAs with miR-122 on the propagation of hepatitis C virus.2018
- Author(s)
  Ono, C., Fukuhara, T., Tamura, T., Mori, H., Sato, A., Fauzyah, Y., Okamoto, T., Chayama, K., Koike, K. and Matsuura, Y.
- Organizer
  第66回日本ウイルス学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] miRNAs comparable with miR-122 on the propagation of hepatitis C virus.2018
- Author(s)
  Ono, C., Fukuhara, T., Okuzaki, D., Tamura, T., Mori, H., Sato, A., Fauzyah, Y., Okamoto, T., Koike, K. and Matsuura, Y.
- Organizer
  The 25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07146
[Presentation] G28A mutation is necessary for an efficient propagation of HCV in miR-122 deficient condition2016
- Author(s)
  小野慎子，福原崇介，元岡大祐，中村昇太，山本聡美，森寛行，上村健太朗，岡本徹，Su Su Hmwe，茶山一彰，脇田隆字，小池和彦，松浦善治
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-10-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19110
[Presentation] CHARACTERIZATION OF MIR-122-INDEPENDENT PROPAGATION OF HCV2016
- Author(s)
  小野慎子，福原崇介，山本聡美，森寛行，上村健太朗，河内悠華子，岡本徹，Su Su Hmwe，脇田隆字，小池和彦，松浦善治
- Organizer
  American Society for Virology 2016 Meeting
- Place of Presentation
  Virginia Tech
- Year and Date
  2016-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19110
[Presentation] G28A mutation facilitates an efficient propagation of HCV in miR-122-independent manner2016
- Author(s)
  小野慎子，福原崇介，元岡大祐，中村昇太，山本聡美，森寛行，上村健太朗，岡本徹，Su Su Hmwe，茶山一彰，脇田隆字，小池和彦，松浦善治
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19110
[Presentation] Characterization of miR-122-independent propagation of HCV2015
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Satomi Yamamoto, Hiroyuki Mori, Toru Okamoto, Su Su Hmwe, Takaji Wakita, Kazuhiko Koike and Yoshiharu Matsuura
- Organizer
  22nd International symposium on Hepatitis C and related viruses
- Place of Presentation
  フランス、ストラスブール
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19110
[Presentation] Characterization of miR-122-independent propagation of HCV2015
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Satomi Yamamoto, Hiroyuki Mori, Toru Okamoto, Su Su Hmwe, Takaji Wakita, Kazuhiko Koike and Yoshiharu Matsuura
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K19110
[Presentation] Innate immuneresponse induced by baculovirus suppresses transgene expression.2013
- Author(s)
  Ono C, Yamamoto S, Ninomiya A, Fukuhara T, Okamoto T, Abe T, Matsuura Y
- Organizer
  American Society for Virology 32nd Annual Meeting
- Place of Presentation
  ペンシルバニア（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] Propagation of HCV in the miR-122-knockout Huh7 cells.2013
- Author(s)
  Ono C, Fukuhara T, Shiokawa M, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
- Organizer
  International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  メルボルン（オーストラリア）
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] miR-122ノックアウトHuh7細胞におけるHCV増殖2013
- Author(s)
  小野慎子、福原崇介、塩川　舞、山本聡美、和田真実、岡本　徹、奥崎大介、松浦善治
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] Characterization of HCV Propagation in miR-122 Knockout Cells
- Author(s)
  Ono C, Fukuhara T, Shiokawa M, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
- Organizer
  33rd American Society for Virology Annual Meeting
- Place of Presentation
  コロラド（アメリカ合衆国）
- Year and Date
  2014-06-21 – 2014-06-25
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] Characterization of HCV propagation in miR-122 knockout cells
- Author(s)
  Ono C, Fukuhara T, Yamamoto S, Wada M, Okamoto T, Okuzaki D, Matsuura Y
- Organizer
  第13回あわじしま感染症・免疫フォーラム
- Place of Presentation
  奈良県新公会堂（奈良）
- Year and Date
  2014-09-23 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] Establishment of mouse liver cell lines susceptible to hepatitis C virus infection
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Mai Shiokawa, Toru Okamoto, Yoshiharu Matsuura
- Organizer
  The 11th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路夢舞台国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] C型肝炎ウイルスに感受性を示すマウス肝臓細胞株の樹立
- Author(s)
  小野慎子、福原崇介、塩川　舞、岡本　徹、松浦善治
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  グランキューブ大阪（大阪）
- Data Source
  KAKENHI-PROJECT-24700429
[Presentation] C型肝炎ウイルスに感受性を示すマウス肝臓細胞株の樹立
- Author(s)
  小野慎子、福原崇介、塩川　舞、岡本　徹、松浦善治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡（福岡）
- Data Source
  KAKENHI-PROJECT-24700429

1. 福原崇介 (70598739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 津田祥美 (70447051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松浦善治

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 脇田隆字

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 齊藤暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ono Chikako 小野 慎子

ONO Chikako 小野 慎子

Research Projects

Research Products

Co-Researchers

Promotion of emerging and re-emerging virus research using high-speed reverse genetics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SARS-CoV-2増殖におけるマイクロRNAの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanistic analysis of persistent infection of HCV in non-hepatic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of adapted HCV that can replicate efficiently in non-hepatic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of mouse infection model of HCVPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Various miRNAs compensate the role of miR-122 on HCV replication.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of selective autophagy in cells replicating hepatitis C virus genome2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of miR-122-independent propagation of HCV2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human cathelicidin compensates for the role of apolipoproteins in the infectious particle formation of HCV.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel permissive cell lines for complete propagation of hepatitis C virus.2014

Author(s)

Journal Title

DOI

Data Source

Ono Chikako 小野慎子

ONO Chikako 小野慎子