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Fukuhara Takasuke  福原 崇介

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… Alternative Names

福原 崇介  フクハラ タカスケ

FUKUHARA Takasuke  福原 崇介

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Researcher Number 70598739
Other IDs
Affiliation (Current) 2022: 北海道大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 北海道大学, 医学研究院, 教授
2017: 大阪大学, 微生物病研究所, 准教授
2011 – 2015: 大阪大学, 微生物病研究所, 助教
Review Section/Research Field
Principal Investigator
Virology / Basic Section 49060:Virology-related
Except Principal Investigator
Digestive surgery / Virology / Basic Section 49070:Immunology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords
Principal Investigator
C型肝炎ウイルス / 肝臓移植 / IL28B / IFN感受性 / 遺伝子改変技術 / アポリポ蛋白質 / オートファジー / マイクロRNA / 遺伝子改変 / アポリポ蛋白 … More / miR-122 / ノックアウト / リバースジェネティクス / SARS-CoV-2 / フラビウイルス / 新興再興感染症 … More
Except Principal Investigator
NLRC5 / 肝移植 / C型肝炎 / 遺伝子多型 / SVR / SNP / C型肝炎 / IL28B遺伝子多型 / ゲノム / SPP / HCV / SARS-CoV-2 / MHC class I / immune evasion / MHC / 癌 / ウイルス感染症 Less
  • Research Projects

    (7 results)
  • Research Products

    (67 results)
  • Co-Researchers

    (29 People)
  •  The role of MHC class I transactivator NLRC5 in COVID-19

    • Principal Investigator
      小林 弘一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Hokkaido University
  •  Development of novel anti-viral therapeuticing an advanced screening technologys us

    • Principal Investigator
      小林 弘一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Hokkaido University
  •  Promotion of emerging and re-emerging virus research using high-speed reverse geneticsPrincipal Investigator

    • Principal Investigator
      福原 崇介
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Hokkaido University
  •  Characterization of SPP involved in pathogenesis of HCV

    • Principal Investigator
      Matsuura Yoshiharu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Osaka University
  •  Genome Editing system in HCV researchPrincipal Investigator

    • Principal Investigator
      Fukuhara Takasuke
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Osaka University
  •  Treatment strategies of recurrent hepatitis C after liver transplantation based on IL28B singlencleotide polymorphism.

    • Principal Investigator
      TAKETOMI Akinobu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Mechanistic analysis about the association of IL28B genetic polymorphism with IFN sensitivity in HCV infected patientsPrincipal Investigator

    • Principal Investigator
      FUKUHARA Takasuke
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Osaka University

All 2022 2021 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant2022

    • Author(s)
      Suzuki Rigel、Yamasoba Daichi、Kimura Izumi、Wang Lei他
    • Journal Title

      Nature

      Volume: 603 Pages: 700-705

    • DOI

      10.1038/s41586-022-04462-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22968, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-21H03802, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-19J20488, KAKENHI-PROJECT-21J21075, KAKENHI-PROJECT-21K07060, KAKENHI-PROJECT-20K15767, KAKENHI-PROJECT-18KK0447
  • [Journal Article] Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation2021

    • Author(s)
      Saito Akatsuki、Irie Takashi、Suzuki Rigel、Maemura Tadashi、Nasser Hesham、Uriu Keiya、Kosugi Yusuke、Other 43 authors、Tanaka Shinya、Nakagawa So、Ikeda Terumasa、Fukuhara Takasuke、Kawaoka Yoshihiro、Sato Kei、The Genotype to Phenotype Japan (G2P-Japan) Consortium
    • Journal Title

      Nature

      Volume: 602 Pages: 300-306

    • DOI

      10.1038/s41586-021-04266-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06382, KAKENHI-PROJECT-19K22968, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-21H03802, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-19J20488, KAKENHI-PROJECT-21K07060, KAKENHI-PROJECT-20K15767, KAKENHI-PROJECT-18KK0447
  • [Journal Article] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity.2021

    • Author(s)
      Motozono Chihiro、Toyoda Mako、Zahradnik Jiri、Saito Akatsuki、Other 19 authors、Ikeda Terumasa、Nakagawa So、Ueno Takamasa、Sato Kei
    • Journal Title

      Cell Host & Microbe

      Volume: 29 Pages: 1124-1136

    • DOI

      10.1016/j.chom.2021.06.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06382, KAKENHI-PROJECT-19K07623, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-19J20488, KAKENHI-PROJECT-20K15767, KAKENHI-PROJECT-18KK0447
  • [Journal Article] Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag2018

    • Author(s)
      Tamura T, Fukuhara T, Uchida T, Ono C, Mori H, Sato A, Fauzyah Y, Okamoto T, Kurosu T, Setoh YX, Imamura M, Tautz N6 Sakoda Y, Khromykh AA, Chayama K, Matsuura Y.
    • Journal Title

      J Virol

      Volume: 92 Pages: 1-19

    • DOI

      10.1128/jvi.01582-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-16J02628, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-16H06432
  • [Journal Article] Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.2017

    • Author(s)
      Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y.
    • Journal Title

      PNAS

      Volume: 114

    • DOI

      10.1073/pnas.1712484114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08759, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-15H04745
  • [Journal Article] Characterization of miR-122-independent propagation of HCV2017

    • Author(s)
      Ono C., Fukuhara T., Motooka D., Nakamura S., Okuzaki D., Yamamoto S., Tamura T., Mori H., Sato A., Uemura K., Fauzyah Y., Kurihara T., Suda T., Nishino A., Hmwe SS., Okamoto T., Tatsumi T., Takehara T., Chayama K., Wakita T., Koike K., Matsuura Y.
    • Journal Title

      PLoS Pathogens

      Volume: 13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Journal Article] Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae2017

    • Author(s)
      Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Mai Shiokawa, Hiroyuki Mori, Kentaro Uemura, Satomi Yamamoto, Takeshi Kurihara, Toru Okamoto, Ryosuke Suzuki, Kentaro Yoshii, Takeshi Kurosu, Manabu Igarashi, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
    • Journal Title

      PLoS Pathogens

      Volume: 13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Journal Article] Quasispecies of Hepatitis C Virus Participate in Cell-Speci c Infectivity2017

    • Author(s)
      Fukuhara T, Yamamoto S, Ono C, Nakamura S, Motooka D, Mori H, Kurihara T, Sato A, Tamura T, Motomura T, Okamoto T, Imamura M, Ikegami T, Yoshizumi T, Soejima Y, Maehara Y, Chayama K, Matsuura Y.
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 7 Pages: 1-10

    • DOI

      10.1038/srep45228

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-16J02628
  • [Journal Article] 1TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.2016

    • Author(s)
      Aizawa S., Okamoto T., Sugiyama Y., Kouwaki T., Ito A., Suzuki T., Ono C., Fukuhara T., Yamamoto M., Okochi M., Hiraga N., Imamura M., Chayama K., Suzuki R., Shoji I., Moriishi K., Moriya K., Koike K., and Matsuura Y.
    • Journal Title

      Nat. Commun.

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Journal Article] TRC8-dependent degradation of the immature core protein regulates propagation and pathogenesis of hepatitis C virus2016

    • Author(s)
      Aizawa S., Okamoto T., Sugiyama Y., Kouwaki T., Ito A., Suzuki T., Ono C., Fukuhara T., Yamamoto M., Okochi M., Hiraga N., Imamura M., Chayama K., Suzuki R., Shoji I., Moriishi K., Moriya K., Koike K., and Matsuura Y.
    • Journal Title

      Nature Communications

      Volume: 7 Pages: 1-12

    • DOI

      10.1038/ncomms11379

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-26461003
  • [Journal Article] Lipoprotein receptors redundantly participate in entry of hepatitis C virus2016

    • Author(s)
      山本聡美、福原崇介、小野慎子、上村健太郎、河内悠華子、塩川舞、森寛行、和田真実、嶋亮一、岡本徹、平賀伸彦、鈴木亮介、茶山一彰、脇田隆字、松浦善治
    • Journal Title

      PLoS Pathogens

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460566
  • [Journal Article] Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus.2015

    • Author(s)
      Fukuhara T, Ono C, Puig-Basagoiti F, Matsuura Y
    • Journal Title

      Trends in Microbiology

      Volume: 23 Pages: 618-629

    • DOI

      10.1016/j.tim.2015.07.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K19110, KAKENHI-PUBLICLY-15H01261, KAKENHI-PROJECT-25460566
  • [Journal Article] Interferon-lambda4 genetic polymorphism is associated with the therapy response for hepatitis C virus recurrence after a living donor liver transplant2014

    • Author(s)
      Konishi H, Motomura T, Matsumoto Y, Harimoto N, Ikegami T, Yoshizumi T, Soejima Y, Shirabe K, Fukuhara T, Maehara Y
    • Journal Title

      J Viral Hepat

      Volume: 21(6) Pages: 397-404

    • DOI

      10.1111/jvh.12154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390328
  • [Journal Article] Amphipathic α-Helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.2014

    • Author(s)
      Fukuhara T, Wada M, Nakamura S, Ono C, Shiokawa M, Yamamoto S, Motomura T, Okamoto T, Okuzaki D, Yamamoto M, Saito I, Wakita T, Koike K, Matsuura Y
    • Journal Title

      PLoS Pathogen

      Volume: 10(12)

    • DOI

      10.1371/journal.ppat.1004534

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390113, KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-24700429, KAKENHI-PUBLICLY-25115511, KAKENHI-PROJECT-25460566, KAKENHI-PROJECT-26670221
  • [Journal Article] Impact of conversion from pegylated interferon-α2b to interferon-α2a for treating recurrent hepatitis C after liver transplantation2013

    • Author(s)
      Ikegami T, Shirabe K, Yoshizumi T, Furusyo N, Kotoh K, Kato M, Shimoda S, Soejima Y, Motomura T, Fukuhara T, Maehara Y
    • Journal Title

      Transplantation

      Volume: 95(6)

    • DOI

      10.1097/tp.0b013e318283a82e

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390328
  • [Journal Article] Expression of miR-122 facilitates an efficient replication in nonhepatic cells upon infection with HCV2013

    • Author(s)
      Kambara H., Fukuhara T., Shiokawa M., Ono C., Ohara Y., Kamitani W., and Matsuura Y.
    • Journal Title

      J.Virol.

      Volume: 86 Pages: 1382-1393

    • DOI

      10.1128/jvi.00567-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390138, KAKENHI-PROJECT-23790502, KAKENHI-PROJECT-23790503, KAKENHI-PROJECT-24390113
  • [Journal Article] Hepatic interferon-gamma-induced protein-10 expression is more strongly associated with liver fibrosis than interleukin-28B single nucleotide polymorphisms in hepatocellular carcinoma resected patients with chronic hepatitis C2013

    • Author(s)
      Konishi H, Shirabe K, Yoshiya S, Ikeda T, Ikegami T, Yoshizumi T, Ikawa-Yoshida A, Motomura T, Fukuhara T, Maehara Y
    • Journal Title

      Hepatol Res

      Volume: 43(11) Pages: 1139-47

    • DOI

      10.1111/hepr.12070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390328
  • [Journal Article] Role of miR-122 and lipid metabolism in HCV infection.2013

    • Author(s)
      福原崇介
    • Journal Title

      J. Gastroenterol.

      Volume: 48(2) Pages: 169-76

    • DOI

      10.1007/s00535-012-0661-5

    • NAID

      10031156302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790502, KAKENHI-PROJECT-24390113
  • [Journal Article] Establishment of a novel permissive cell line for propagation of hepatitis C virus by the expression of microRNA122.2012

    • Author(s)
      Kambara H, Fukuhara T, et al
    • Journal Title

      J.Virol.

      Volume: 86 Pages: 1382-1393

    • DOI

      10.1128/jvi.06242-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790502, KAKENHI-PROJECT-24390113
  • [Journal Article] V5-drainage-preserved right lobe grafts improve graft congestion for living donor liver transplantation2012

    • Author(s)
      Toshima T, Taketomi A, Ikegami T, Fukuhara T, et al
    • Journal Title

      Transplantation

      Volume: 15 Pages: 929-935

    • DOI

      10.1097/tp.0b013e3182488bd8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Journal Article] Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype2012

    • Author(s)
      Motomura T, Koga E, Taketomi A, Fukuhara T, et al
    • Journal Title

      Hepatol Res

      Volume: 42 Pages: 288-295

    • DOI

      10.1111/j.1872-034x.2011.00927.x

    • NAID

      10031144238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Journal Article] Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype2012

    • Author(s)
      Motomura T, Koga E, Taketomi A, Fukuhara T, Mano Y, Muto J, Konishi H, Toshima T, Uchiyama H, Yoshizumi T, Shirabe K, Maehara Y
    • Journal Title

      Hepatol Res

      Volume: 42(3) Pages: 288-95

    • NAID

      10031144238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390328
  • [Journal Article] Role of miR-122 and lipid metabolism in HCV infection2012

    • Author(s)
      Fukuhara T, et al
    • Journal Title

      J Gastroenterol

      Volume: (in press)

    • NAID

      10031156302

    • Data Source
      KAKENHI-PROJECT-23790502
  • [Journal Article] CD44 participates in IP-10 induction in cells in which hepatitis C virus RNA is replicating, through an interaction with Toll-like receptor 2 and hyaluronan.2012

    • Author(s)
      Abe T
    • Journal Title

      J Virol

      Volume: 86 Pages: 6159-6170

    • DOI

      10.1128/jvi.06872-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689030, KAKENHI-PROJECT-23790502
  • [Journal Article] Baculovirus GP64-mediated entry into mammalian cells.2012

    • Author(s)
      Kataoka C, Kaname Y, Taguwa S AbeT, Fukuhara T, et al
    • Journal Title

      J Virol

      Volume: 86 Pages: 2610-2620

    • DOI

      10.1128/jvi.06704-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Journal Article] Neutrophil-lymphocyte ratio reflects hepatocellular carcinoma recurrence after liver transplantation via inflammatory microenvironment2012

    • Author(s)
      Motomura T, Shirabe K, Mano Y, Muto J, Toshima T, Umemoto Y, Fukuhara T, et al
    • Journal Title

      J Hepatol

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23790502
  • [Journal Article] The impact of IL28B genetic variants on recurrent hepatitis C in liver transplantation: significant lessons from a dual graft case2011

    • Author(s)
      Motomura T., et al
    • Journal Title

      Am J Transplant

      Volume: 11 Pages: 1325-1329

    • DOI

      10.1111/j.1600-6143.2011.03537.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-22659246, KAKENHI-PROJECT-23790502
  • [Journal Article] Involvement of cyclophilin B in the replication of Japanese encephalitis virus2011

    • Author(s)
      Kambara H., Tani H., Mori Y., Abe T., Katoh H., Fukuhara T., Taguwa S., Moriishi K, and Matsuura Y.
    • Journal Title

      Virology

      Volume: 412 Pages: 211-219

    • DOI

      10.1016/j.virol.2011.01.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390138, KAKENHI-PROJECT-23689028, KAKENHI-PROJECT-23790502
  • [Journal Article] Intracellular delivery of serum-derived hepatitis C virus2011

    • Author(s)
      Fukuhara T, et al
    • Journal Title

      Microbes Infect

      Volume: 13 Pages: 405-12

    • DOI

      10.1016/j.micinf.2011.01.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-21390138, KAKENHI-PROJECT-22659246, KAKENHI-PROJECT-23790502
  • [Journal Article] Heterogeneous nuclear ribonucleoprotein A2 participates in the replication of Japanese encephalitis virus through an interaction with viral proteins and RNA2011

    • Author(s)
      Hiroshi Katoh
    • Journal Title

      J Virol.

      Volume: 85(21) Pages: 10976-10988

    • DOI

      10.1128/jvi.00846-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03343, KAKENHI-PROJECT-21390138, KAKENHI-PROJECT-23689028, KAKENHI-PROJECT-23790502, KAKENHI-PROJECT-23790503
  • [Presentation] Viral secretory glycoproteins of Pestivirus and Flavivirus have similar roles with exchangeable apolipoproteins on the formation of infectious HCV particles2017

    • Author(s)
      Takasuke Fukuhara, Tomokazu Tamura, Mai Shiokawa, Chikako Ono, Satomi Yamamoto Hiroyuki Mori, Asuka Sato, Shinya Yamada, Toru Okamoto, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
    • Organizer
      24th International Symposium on Heepatitis C Virus and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Characterization of selective autophagy induced by HCV RNA replication2017

    • Author(s)
      Hiroyuki Mori, Takasuke Fukuhara, Chikako Ono, Tomokazu Tamura, Asuka Sato, Yuzy Fauzyah, Shinya Yamada, Toru Okamoto, Masami Wada, Takeshi Noda, Tamotsu Yoshimori, Yoshiharu Matsuura
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] C型肝炎ウイルスの増殖と病原性に関与する宿主因子2017

    • Author(s)
      松浦善治、福原崇介、岡本 徹
    • Organizer
      北大部局横断シンポジウム 第2回北大部局横断シンポジウム「免疫・癌・感染」
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Engineering of Small Reporter-Tagged Flaviviridae Viruses Applicable to Antiviral Screening and in vivo Dynamics2017

    • Author(s)
      Tomokazu Tamura, Takasuke Fukuhara, Akatuski Saito, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Tatuso Shioda, Kazuaki Chayama, Yoshiharu Matsuura
    • Organizer
      24th International Symposium on Heepatitis C Virus and Related Viruses
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Engineering of small reporter-tagged Flaviviridae viruses applicable to antiviral screening and in vivo dynamics2017

    • Author(s)
      Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Kazuaki Chayama, Yoshiharu Matsuura
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Viral secretory proteins Erns and NS1 play comparable roles with apolipoproteins in the infectious particle formation of Flaviviridae2017

    • Author(s)
      Takasuke Fukuhara, Tomokazu Tamura, Mai Shiokawa, Chikako Ono, Satomi Yamamoto, Hiroyuki Mori, Takeshi Kurihara, Asuka Sato, Kentaro Uemura, Toru Okamoto, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
    • Organizer
      The American Society for Virology (ASV) the 36th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] C型肝炎ウイルスの増殖と病原性に関与する宿主因子2017

    • Author(s)
      Yoshiharu Matsuura, Takasuke Fukuhara, Toru Okamoto
    • Organizer
      北大部局横断シンポジウム 第2回北大部局横断シンポジウム「免疫・癌・感染」
    • Place of Presentation
      北海道大学
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Characterization of Flaviviridae viruses possessing a reporter gene2017

    • Author(s)
      Tomokazu Tamura, Takasuke Fukuhara, Chikako Ono, Hiroyuki Mori, Takeshi Kurihara, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Yoshiharu Matsuura
    • Organizer
      The American Society for Virology (ASV) the 36th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Involvement of other miRNA on the propagation of HCV in miR-1-deficient cells2017

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuaki Chayama, Kazuhiko Koike, Yoshiharu Matsuura
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Viral secretory glycoproteins Erns and NS1 play comparable roles with apolipoproteins in infectious particle formation of Flaviviridae2017

    • Author(s)
      Fukuhara Takasuke, Tamura Tomokazu, Matsuura Yoshiharu
    • Organizer
      第65回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag2017

    • Author(s)
      Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Kazuaki Chayama, Yoshiharu Matsuura
    • Organizer
      第16回あわじしま感染症・免疫フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Characterization of miR-122-independent propagation of HCV2017

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuaki Chayama, Kazuhiko Koike, Yoshiharu Matsuura
    • Organizer
      第16回あわじしま感染症・免疫フォーラム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Roles of miR-574-5p and miR-504-3p on the propagation of HCV in miR-122-deficient cells2017

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuhiko Koike, Yoshiharu Matsuura
    • Organizer
      The American Society for Virology (ASV) the 36th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Evaluation of γ-secretase inhibitors for HCV therapy2016

    • Author(s)
      Junki Hirano, Yukari Sugiyama, Tatsuya Suzuki, Shinji Kusakabe, Takasuke Fukuhara, Toru Okamoto, Yoshiharu Matsuura
    • Organizer
      23rd International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2016-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Single peptide peptidase a target for anti-HCV drug2016

    • Author(s)
      Toru Okamoto,Junki Hirano,Tatsuya Suzuki, ,Shinji Kusakabe,Takasuke Fukuhara Kohji Moriishi,Kazuhiko Koike and Yoshiharu Matsuura
    • Organizer
      23rd International Symposium on Hepatitis C Virus and Related Viruses
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2016-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Roles of lipoprotein receptors in the entry of hepatitis C virus2015

    • Author(s)
      福原崇介、山本聡美、小野慎子、森寛行、Puig-Basagoiti Francesc、岡本徹、松浦善治
    • Organizer
      The 22nd International Meeting on HCV and Related Viruses
    • Place of Presentation
      ストラスブルグ、フランス
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460566
  • [Presentation] Signal peptide peptidase regulates propagation and pathogenesis of Hepatitis C Virus2015

    • Author(s)
      Toru Okamoto,Yukari Sugiyama,Ayano Ito, Takasuke Fukuhara, and Yoshiharu Matusuura
    • Organizer
      第14回あわじしま感染症免疫フォーラム
    • Place of Presentation
      淡路市、兵庫県
    • Year and Date
      2015-09-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] TRC8-dependent proteasome degradation of immature core protein participates in pathogenesis of HCV2015

    • Author(s)
      Toru Okamoto, Yukari Sugiyama, Takahisa Kouwaki, Ayano Ito, Takasuke Fukuhara, Kohji Moriishi, Kazuhiko Koike, and Yoshiharu Matusuura
    • Organizer
      The 22nd International Meeting on HCV and Related Viruses
    • Place of Presentation
      Strasburg, France
    • Year and Date
      2015-10-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] Characterization of miR-122-independent propagation of HCV2015

    • Author(s)
      小野慎子、福原崇介、山本聡美、森寛行、岡本徹、Su Su Hmwe、脇田隆字、小池和彦、松浦善治
    • Organizer
      The 22nd International Meeting on HCV and Related Viruses
    • Place of Presentation
      ストラスブルグ、フランス
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460566
  • [Presentation] Processing of core protein by signal peptide peptidase participates in propagation and pathogenesis of hepatitis C virus2015

    • Author(s)
      Toru Okamoto, Sayaka Aizawa, Yukari Sugiyama, Takahisa Kouwaki, Takasuke Fukuhara, Kohji Moriishi, Kazuhiko Koike, and Yoshiharu Matusuura
    • Organizer
      The 34th Annual Meeting of the American Society for Virology
    • Place of Presentation
      London, Canada
    • Year and Date
      2015-07-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04736
  • [Presentation] C型肝炎ウイルスの感染によって誘導されるオートファジーの性状2013

    • Author(s)
      福原崇介
    • Organizer
      第61回日本ウイルス学会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-25460566
  • [Presentation] C型肝炎ウイルスに感受性を示すマウス肝臓細胞株の樹立2012

    • Author(s)
      小野慎子、福原崇介、塩川舞、岡本徹、松浦善治: 一般講演
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] Establishment of Mouse Liver Cell Lines Susceptible to Hepatitis C Virus Infection2012

    • Author(s)
      Ono C, Fukuhara T, Shiokawa M, Okamoto T, and Matsuura Y
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] 一般講演:HCV感染の肝細胞指向性はmiR-122の発現と脂質代謝によって規定される2012

    • Author(s)
      福原崇介、塩川舞、小野慎子、山本聡美、寒原裕登、加藤大志、岡本徹、奥崎大介、松浦善治
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] miR-122 expression and lipid metabolism participate in cell tropism of hepatitis C virus infection. The American Society for Virology2012

    • Author(s)
      Fukuhara T, Kambara H, Shiokawa M, Ono C, Kato H, Okamoto T, and Matsuura Y
    • Organizer
      31th Annual Meeting
    • Place of Presentation
      University of Wisconsin-Madison
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] nvolvement of Human Liver-specific Factors in a Complete Propagation of Hepatitis C Virus2012

    • Author(s)
      Shiokawa M, Fukuhara T, Ono C, Okamoto T, and Matsuura Y.
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] 一般講演:C型肝炎ウイルスの肝細胞指向性におけるmiR-122と脂質代謝の役割2012

    • Author(s)
      福原崇介
    • Organizer
      第11回Hepatitis Expert Meeting
    • Place of Presentation
      東京
    • Year and Date
      2012-08-25
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] HCVの非肝臓系細胞株に対する感染培養システムの確立と肝外病変成立に関わる宿主因子の同定2012

    • Author(s)
      福原崇介
    • Organizer
      JDDW2012
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] Identification of Host Factors Interact with Hepatitis B virus X Protein2012

    • Author(s)
      Kouwaki T, Pham DN, Fukuhara T, Okamoto T, and Matsuura Y.
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] Quasispecies Plays an Important Role in Cell Tropism of Hepatitis C Virus2012

    • Author(s)
      Fukuhara T, Motomura T, Shiokawa M, Ono C, Kambara H, Okamoto T, Shirabe K, Maehara Y, and Matsuura Y.
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] MiR-122 expression and lipid metabolism participate in the cell tropism of HCV infection2012

    • Author(s)
      Fukuhara T, Shiokawa M, Arimoto M, Ono C, Katoh H, Kambara H, Okamoto T, and Matsuura Y.
    • Organizer
      19th International Meeting on HCV and Related Viruses
    • Place of Presentation
      Venice, Italy
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] パネルディスカッション:HCVの非肝臓系細胞株に対する感染培養システムの確立と肝外病変成立に関わる宿主因子の同定2012

    • Author(s)
      福原崇介、本村貴志、松浦善治
    • Organizer
      JDDW
    • Place of Presentation
      神戸
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] 一般講演:C型肝炎ウイルスの粒子産生に関与するヒト肝細胞特異因子の解析と新規感受性細胞株の樹立2012

    • Author(s)
      塩川舞、福原崇介、小野慎子、山本聡美、岡本徹、松浦善治
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] 一般講演:HuH-7由来オーバル様細胞におけるHCV感受性の解析2012

    • Author(s)
      伊藤昌彦、鈴木亮介、福原崇介、松浦善治、脇田隆字、鈴木哲朗
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-13
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] 肝移植症例におけるIL28B、ITPAおよびMICA遺伝子多型の検討2011

    • Author(s)
      福原崇介
    • Organizer
      広島肝臓プロジェクト研究センターシンポジウム
    • Place of Presentation
      ホテルグランビア広島
    • Data Source
      KAKENHI-PROJECT-23790502
  • [Presentation] Characterization of HCV Propagation in miR-122 Knockout Cells.

    • Author(s)
      Chikako Ono, Takasuke Fukuhara, Mai Shiokawa, Satomi Yamamoto, Masami Wada, Toru Okamoto, Daisuke Okuzaki, Yoshiharu Matsuura
    • Organizer
      33rd American Society for Virology, Annual Meeting
    • Place of Presentation
      Colorado(U.S.A.)
    • Year and Date
      2014-06-20 – 2014-06-25
    • Data Source
      KAKENHI-PROJECT-25460566
  • [Presentation] Exchageable apolipoproteins participate in the particle formation of hepatitis C virus.

    • Author(s)
      Takasuke Fukuhara, Masami Wada, Shota Nakamura, Chikako Ono, Satomi Yamamoto, Mai Shiokawa, Toru Okamoto, Yoshiharu Matsuura
    • Organizer
      33rd American Society for Virology, Annual Meeting
    • Place of Presentation
      Colorado(U.S.A.)
    • Year and Date
      2014-06-20 – 2014-06-25
    • Data Source
      KAKENHI-PROJECT-25460566
  • 1.  MATSUURA Yoshiharu (50157252)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 28 results
  • 2.  小林 弘一 (60817162)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  應田 涼太 (90817321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TAKETOMI Akinobu (70363364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  MAEHARA Yoshihiko (80165662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  SHIRABE Ken (70264025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  YOSHIZUMI Tomoharu (80363373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 8.  UCHIYAMA Hideaki (70380425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  OKAMOTO Toru (80628595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 24 results
  • 10.  小野 慎子 (30626437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  津田 祥美 (70447051)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  澤 洋文 (30292006)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  田村 友和 (00772360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HORII Toshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  SASAI Miwa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  齊藤 暁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  入江 崇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  田中 伸哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  津田 真寿美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 20.  東岸 任弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  鈴木 信弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  山本 雅裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  森田 英嗣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 24.  鈴木 穣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  本園 千尋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  勝二 郁夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  脇田 隆字
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  小池 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  斎藤 泉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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