Hatano Ryo 波多野良

Researcher Number	30638789
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 順天堂大学, 大学院医学研究科, 特任准教授 2021: 順天堂大学, 大学院医学研究科, 特任助教 2018 – 2020: 順天堂大学, 医学(系)研究科(研究院), 特任助教 2016 – 2017: 順天堂大学, 医学(系)研究科(研究院), 特任研究員 2015 – 2016: 順天堂大学, 医学(系)研究科(研究院), 日本学術振興会特別研究員PD 2014: 順天堂大学, 医学(系)研究科(研究院), 日本学術振興会特別研究員(PD)
Review Section/Research Field	Principal Investigator Collagenous pathology/Allergology / Basic Section 49030:Experimental pathology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 49030:Experimental pathology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Collagenous pathology/Allergology
Keywords	Principal Investigator 慢性炎症 / IL-26 / CD26 / 自己免疫疾患 / CD26/DPPIV / 臓器線維化 / 抗体療法 / 線維化 / 好中球 / 免疫チェックポイント分子 … More / 免疫制御 / 胸水 / 悪性中皮腫 / 全身性エリテマトーデス / ヒトT細胞 / 腫瘍免疫 / ヒト化抗CD26抗体 / 悪性胸膜中皮腫 / CD26/DPP4 / Th17 / CD26共刺激 / 慢性GVHD / 炎症性腸疾患 / 炎症性サイトカイン / 分子標的療法 / 慢性炎症疾患 / 血管新生 / 乾癬 / 中和抗体 / IL-10 / 細胞傷害活性 / 共刺激 / ヒト免疫 / 共刺激分子 / 細胞傷害性T細胞 / SLE / T細胞 … More Except Principal Investigator 炎症性腸疾患 / 慢性炎症 / IL-26 / 自己免疫疾患 / ヒト免疫 / 核酸 / 抗体療法 / 上皮間葉転換 / 大腸癌転移 / 抗CD26抗体 / 移植片対宿主病 / 関節炎 / 関節炎モデル / IL-26中和抗体 / 炎症性サイトカイン / 小児血液学 / 血液免疫学 / 移植免疫学 / 慢性GVHD / BTLA / 臨床免疫学 / LAG-3 / CD26 / SLE / 腫瘍免疫 / 免疫制御 / 悪性胸膜中皮腫 / 全身性エリテマトーデス / 免疫チェックポイント分子 / IL-10 / 共刺激分子 / T細胞 / CD26/DPPIV Less

ヒト化抗CD26抗体を用いた大腸癌の転移病巣に対する新規治療法の開発
- Principal Investigator
  
  岩尾憲明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Molecular understanding of an innovative therapy for chronic inflammatory diseases targeting human Th17 cytokine IL-26
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Basic research for the development of novel therapy targeting neutrophils and organ fibrosis to regulate chronic inflammationPrincipal Investigator
- Principal Investigator
  
  波多野良
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Molecular understanding of tumor immunology of malignant pleural mesothelioma targeting human CD26/DPPIV molecule.Principal Investigator
- Principal Investigator
  
  Hatano Ryo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Understanding of detailed pathology and development of novel molecular targeted therapy for the treatment of refractory chronic inflammatory diseases based on the inflammatory cytokine IL-26
- Principal Investigator
  
  Morimoto Chikao
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Development of a novel therapy for refractory inflammatory diseases targeting an inflammatory cytokine IL-26Principal Investigator
- Principal Investigator
  
  Hatano Ryo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Molecular understanding of CD26-mediated immune regulatory mechanism and development of novel molecular targeted therapy for the treatment of refractory autoimmune diseases
- Principal Investigator
  
  Morimoto Chikao
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Analysis of CD8+CD26-positive/negative T cell subsets for the development of an innovative therapy and elucidating the pathophysiology of refractory autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Hatano Ryo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent

[Book] Advances in Medicine and Biology2019
- Author(s)
  Okamoto T, Hatano R, Nakano K, Yamada T, Yamazaki H, Kaneko Y, Dang NH, Morimoto C, Ohnuma K.
- Total Pages
  21
- Publisher
  Nova Science Publishers, Inc., Hauppauge, NY
- Data Source
  KAKENHI-PROJECT-17K10008
[Book] Advances in Medicine and Biology2018
- Author(s)
  Hatano R, Ohnuma K, Yamada T, Okamoto T, Komiya E, Otsuka H, Itoh T, Yamazaki H, Iwao N, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  45
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16H05345
[Book] Advances in Medicine and Biology2018
- Author(s)
  Hatano R, Ohnuma K, Yamada T, Okamoto T, Komiya E, Otsuka H, Itoh T, Yamazaki H, Iwao N, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  44
- Publisher
  Nova Science Publishers, Inc., Hauppauge, NY
- Data Source
  KAKENHI-PROJECT-17K10008
[Book] Advances in Medicine and Biology2018
- Author(s)
  Hatano R, Ohnuma K, Yamada T, Okamoto T, Komiya E, Otsuka H, Itoh T, Yamazaki H, Iwao N, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  44
- Publisher
  Nova Science Publishers, Inc., Hauppauge, NY
- Data Source
  KAKENHI-PROJECT-26860760
[Book] Horizons in Cancer Research2017
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  33
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16H05345
[Book] Horizons in Cancer Research.2017
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  34
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-26860760
[Book] A New Horizon in Malignant Pleural Mesothelioma Management, Horizons in Cancer Researc2016
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, KanekoY, Dang NH, Morimoto C1.Ohnuma K, Hatano R, Yamazaki H, KanekoY, Dang NH, Morimoto C
- Total Pages
  220
- Publisher
  Nova Science Publishers,Inc
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] Functional Roles of CD26/DPP4 in Bleomycin-Induced Pulmonary Hypertension Associated with Interstitial Lung Disease2024
- Author(s)
  Okaya Tadasu、Kawasaki Takeshi、Sato Shun、Koyanagi Yu、Tatsumi Koichiro、Hatano Ryo、Ohnuma Kei、Morimoto Chikao、Kasuya Yoshitoshi、Hasegawa Yoshinori、Ohara Osamu、Suzuki Takuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 2 Pages: 748-748
- DOI
  10.3390/ijms25020748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16163, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-23K27395
[Journal Article] Functional roles of CD26/DPP4 in lipopolysaccharide-induced lung injury2024
- Author(s)
  Sato Shun、Kawasaki Takeshi、Hatano Ryo、Koyanagi Yu、Takahashi Yukiko、Ohnuma Kei、Morimoto Chikao、Dudek Steven M.、Tatsumi Koichiro、Suzuki Takuji
- Journal Title
  
  American Journal of Physiology-Lung Cellular and Molecular Physiology
  
  Volume: - Issue: 5 Pages: L562-L573
- DOI
  10.1152/ajplung.00392.2022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16163, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-23K27395
[Journal Article] Functional roles of <scp>CD26</scp> / <scp>DPP4</scp> in bleomycin‐induced pulmonary fibrosis2023
- Author(s)
  Koyanagi Yu、Kawasaki Takeshi、Kasuya Yoshitoshi、Hatano Ryo、Sato Shun、Takahashi Yukiko、Ohnuma Kei、Morimoto Chikao、Dudek Steven M.、Tatsumi Koichiro、Suzuki Takuji
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 6
- DOI
  10.14814/phy2.15645
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16163, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-23K24337
[Journal Article] Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies2023
- Author(s)
  Kobayashi Eiji、Kamihara Yusuke、Arai Miho、Wada Akinori、Kikuchi Shohei、Hatano Ryo、Iwao Noriaki、Susukida Takeshi、Ozawa Tatsuhiko、Adachi Yuichi、Kishi Hiroyuki、Dang Nam H.、Yamada Taketo、Hayakawa Yoshihiro、Morimoto Chikao、Sato Tsutomu
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 16 Pages: 2059-2059
- DOI
  10.3390/cells12162059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-22K19387, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-23K27395
[Journal Article] DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies2023
- Author(s)
  Kikuchi S, Wada A, Kamihara Y, Okazaki K, Jawaid P, Rehman MU, Kobayashi E, Susukida T, Minemura T, Nabe Y, Iwao N, Ozawa T, Hatano R, Yamada M, Kishi H, Matsuya Y, Mizuguchi M, Hayakawa Y, Dang NH, Sakamoto Y, Morimoto C, Sato T
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 7 Pages: 1100-1100
- DOI
  10.3390/cells12071100
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-21K07237, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-23K27395, KAKENHI-PROJECT-23K27423
[Journal Article] Anti-glomerular Basement Membrane Disease Concomitant with MPO-ANCA Positivity Concurrent with High Serum Levels of Interleukin-26 Following Coronavirus Disease 2019 Vaccination2023
- Author(s)
  Kobayashi S, Fugo K, Hatano R, Yamazaki K, Morimoto C, Terawaki H.
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 7 Pages: 1043-1048
- DOI
  10.2169/internalmedicine.1027-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-23K27395
[Journal Article] Humanized anti-IL-26 monoclonal antibody as a novel targeted therapy for chronic graft-versus-host disease.2022
- Author(s)
  Hatano R, Itoh T, Otsuka H, Saeki H, Yamamoto A, Song D, Shirakawa Y, Iyama S, Sato T, Iwao N, Harada N, Aune TM, Dang NH, Kaneko Y, Yamada T, Morimoto C, Ohnuma K.
- Journal Title
  
  Am J Transplant.
  
  Volume: 22 Pages: 2804-2820
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03471
[Journal Article] Humanized anti-IL-26 monoclonal antibody as a novel targeted therapy for chronic graft-versus-host disease2022
- Author(s)
  Hatano Ryo、Itoh Takumi、Otsuka Haruna、Saeki Harumi、Yamamoto Ayako、Song Dan、Shirakawa Yuki、Iyama Satoshi、Sato Tsutomu、Iwao Noriaki、Harada Norihiro、Aune Thomas M.、Dang Nam H.、Kaneko Yutaro、Yamada Taketo、Morimoto Chikao、Ohnuma Kei
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 22 Issue: 12 Pages: 2804-2820
- DOI
  10.1111/ajt.17178
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19387, KAKENHI-PROJECT-21K16389, KAKENHI-PROJECT-22K15400, KAKENHI-PROJECT-20K07683
[Journal Article] Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV2022
- Author(s)
  Komiya Eriko、Tominaga Mitsutoshi、Hatano Ryo、Kamikubo Yuji、Toyama Sumika、Sakairi Hakushun、Honda Kotaro、Itoh Takumi、Kamata Yayoi、Tsurumachi Munehiro、Kishi Ryoma、Ohnuma Kei、Sakurai Takashi、Morimoto Chikao、Takamori Kenji
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 149 Issue: 3 Pages: 1085-1096
- DOI
  10.1016/j.jaci.2021.08.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K08756, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-20K08680, KAKENHI-PROJECT-21K16307, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-23K20320, KAKENHI-PROJECT-23K24217
[Journal Article] IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells2021
- Author(s)
  Itoh Takumi、Hatano Ryo、Horimoto Yoshiya、Yamada Taketo、Song Dan、Otsuka Haruna、Shirakawa Yuki、Mastuoka Shuji、Iwao Noriaki、Aune Thomas M.、Dang Nam H.、Kaneko Yutaro、Okumura Ko、Morimoto Chikao、Ohnuma Kei
- Journal Title
  
  Cell Death and Disease
  
  Volume: 12 Issue: 6 Pages: 520-520
- DOI
  10.1038/s41419-021-03787-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-21K16389
[Journal Article] Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody.2021
- Author(s)
  Kaneko Y, Hatano R, Hirota N, Isambert N, Trillet-Lenoir V, You B, Alexandre J, Zalcman G, Valleix F, Podoll T, Umezawa Y, Takao S, Iwata S, Hosono O, Taguchi T, Yamada T, Dang NH, Ohnuma K, Angevin E, Morimoto C.
- Journal Title
  
  Biomark Res
  
  Volume: 9 Issue: 1 Pages: 21-21
- DOI
  10.1186/s40364-021-00273-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K22542
[Journal Article] Single-cell atlas of colonic CD8+ T-cells in ulcerative colitis.2020
- Author(s)
  Corridoni D, Antanaviciute A, Gupta T, Fawkner-Corbett D, Aulicino A, Jagielowicz M, Parikh K, Repapi E, Taylor S, Ishikawa D, Hatano R, Yamada T, Xin W, Slawinki H, Bowden R, Napolitani G, Brain O, Morimoto C, Koohy H, Simmons A.
- Journal Title
  
  Nat Med
  
  Volume: 26 Issue: 9 Pages: 1480-1490
- DOI
  10.1038/s41591-020-1003-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K22542
[Journal Article] Single-cell atlas of colonic CD8+ T-cells in inflammatory bowel disease.2020
- Author(s)
  Corridoni D, Antanaviciute A, Gupta T, Fawkner-Corbett D, Aulicino A, Jagielowicz M, Parikh K, Repapi E, Taylor S, Ishikawa D, Hatano R, Yamada T, Xin W, Slawinki H, Bowden R, Napolitani G, Brain O, Morimoto C, Koohy H, Simmons A.
- Journal Title
  
  Nat Med
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Journal Article] GVHDの発症と慢性炎症.2019
- Author(s)
  岩尾憲明、大沼圭、波多野良、大塚春奈、古宮栄利子、伊藤匠、森本幾夫.
- Journal Title
  
  BIO Clinica
  
  Volume: 8 Pages: 128-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10008
[Journal Article] Rheumatic diseases associated with immune checkpoint inhibitors in cancer immunotherapy.2019
- Author(s)
  Ohnuma K, Hatano R, Dang NH, Morimoto C.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 印刷中 Issue: 5 Pages: 721-732
- DOI
  10.1080/14397595.2018.1532559
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-16H05345
[Journal Article] Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.2019
- Author(s)
  Hatano R, Itoh T, Otsuka H, Okamoto S, Komiya E, Iwata S, Aune TM, Dang NH, Kuwahara-Arai K, Ohnuma K, Morimoto C.
- Journal Title
  
  mabs.
  
  Volume: 11 Issue: 8 Pages: 1428-1442
- DOI
  10.1080/19420862.2019.1654305
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-19K21278
[Journal Article] Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens2019
- Author(s)
  Hatano R, Yamada T, Madokoro H, Otsuka H, Komiya E, Itoh T, Narita Y, Iwata S, Yamazaki H, Matsuoka S, Dang NH, Morimoto C
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 6 Pages: e0218330-e0218330
- DOI
  10.1371/journal.pone.0218330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22542, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-19K21278
[Journal Article] DPP8 is a novel therapeutic target for multiple myeloma.2019
- Author(s)
  Sato T, Tatekoshi A, Takada K, Iyama S, Kamihara Y, Jawaid P, Rehman MU, Noguchi K, Kondo T, Kajikawa S, Arita K, Wada A, Murakami J, Arai M, Yasuda I, Dang NH, Hatano R, Iwao N, Ohnuma K, Morimoto C.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 18094-18094
- DOI
  10.1038/s41598-019-54695-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-17K10008
[Journal Article] Biological effects of IL-26 on T cell-mediated skin inflammation, including psoriasis.2019
- Author(s)
  Itoh T, Hatano R, Komiya E, Otsuka H, Narita Y, Aune TM, Dang NH, Matsuoka S, Naito H, Tominaga M, Takamori K, Morimoto C, Ohnuma K.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 139 Issue: 4 Pages: 878-889
- DOI
  10.1016/j.jid.2018.09.037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-19K21278, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-18K07396
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target in selected immune disorders and cancers.2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860760
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target in selected immune disorders and cancers2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C
- Journal Title
  
  Front Biosci
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] 抗CD26抗体(anti-CD26 monoclonal antibody).2018
- Author(s)
  大沼圭、波多野良、森本幾夫.
- Journal Title
  
  腫瘍内科
  
  Volume: 22 Pages: 190-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10008
[Journal Article] Establishment of intestinal epithelial cell line derived from fetal mouse colon and its immune-related characteristics - Comparison with mouse small intestinal epithelial cell line -.2018
- Author(s)
  Iwamoto T, Totsuka M, Yamada K, Emoto T, Hatano R, Shimizu M.
- Journal Title
  
  Cytotechnology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860760
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target in selected immune disorders and cancers.2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Journal Article] Establishment of intestinal epithelial cell line derived from fetal mouse colon and its immune-related characteristics - Comparison with mouse small intestinal epithelial cell line -.2018
- Author(s)
  Iwamoto T, Totsuka M, Yamada K, Emoto T, Hatano R, Shimizu M.
- Journal Title
  
  Cytotechnology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10008
[Journal Article] Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22.2018
- Author(s)
  Okamoto T, Yamazaki H, Hatano R, Yamada T, Kaneko Y, Xu CW, Dang NH, Ohnuma K, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 504 Issue: 2 Pages: 491-498
- DOI
  10.1016/j.bbrc.2018.08.193
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-18H02782
[Journal Article] A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus2017
- Author(s)
  Komiya, E. Hatano, R. Otsuka, H. Itoh, T. Yamazaki, H. Yamada, T. Dang, N. H. Tominaga, M. Suga, Y. Kimura, U. Takamori, K. Morimoto, C. Ohnuma, K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 印刷中 Issue: 3 Pages: 212-221
- DOI
  10.1016/j.jdermsci.2017.03.005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-16K08997
[Journal Article] Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains2016
- Author(s)
  Nomura, S. Iwata, S. Hatano, R. Komiya, E. Dang, N. H. Iwao, N. Ohnuma, K. Morimoto, C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 474 Issue: 1 Pages: 111-7
- DOI
  10.1016/j.bbrc.2016.04.081
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate2016
- Author(s)
  Ohnuma, K. Hatano, R. Itoh, T. Iwao, N. Dang, N. H. Morimoto, C.
- Journal Title
  
  Crit Rev Immunol
  
  Volume: 36 Issue: 3 Pages: 239-267
- DOI
  10.1615/critrevimmunol.2016018772
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] Establishment of anti-mesothelioma monoclonal antibodies2016
- Author(s)
  Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O
- Journal Title
  
  BMC Res Notes
  
  Volume: 9 Issue: 1 Pages: 324-324
- DOI
  10.1186/s13104-016-2128-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway.2015
- Author(s)
  Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, Dang NH, Okumura K, Morimoto C.
- Journal Title
  
  J Immunol.
  
  Volume: Vol 194 Issue: 3 Pages: 960-72
- DOI
  10.4049/jimmunol.1402143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-26293087
[Journal Article] DPP4 in anti-tumor immunity: going beyond the enzyme.2015
- Author(s)
  Ohnuma K, Hatano R, Morimoto C.
- Journal Title
  
  Nat Immunol.
  
  Volume: 16 Issue: 8 Pages: 791-2
- DOI
  10.1038/ni.3210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] Modulation of immunological responses and amelioration of collagen-induced arthritis by the novel roxithromycin derivative 5-I.2015
- Author(s)
  Otsuki N, Iwata S, Yamada T, Hosono O, Dang NH, Hatano R, Ohnuma K, Morimoto C.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 25 Issue: 4 Pages: 562-70
- DOI
  10.3109/14397595.2014.983262
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] The Role of Cas-L/NEDD9 as a Regulator of Collagen-induced Arthritis in a Murine Model2015
- Author(s)
  Tomoki Katayose, Satoshi Iwata, Naoki Oyaizu, Osamu Hosono, Taketo Yamada, Nam H Dang, Ryo Hatano, Hirotoshi Tanaka, Kei Ohnuma, Chikao Morimoto
- Journal Title
  
  Biochem Bilphys Res Commun
  
  Volume: 印刷中 Issue: 4 Pages: 1069-75
- DOI
  10.1016/j.bbrc.2015.03.156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390236, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] Comparison of Two Commercial ELISAs against an In-House ELISA for Measuring Soluble CD26 in Human Serum.2015
- Author(s)
  Ohnuma K, Saito T, Hatano R, Hosono O, Iwata S, Dang NH, Ninomiya H, Morimoto C.
- Journal Title
  
  J Clin Lab Anal.
  
  Volume: Vol 29 Issue: 2 Pages: 106-11
- DOI
  10.1002/jcla.21736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-23591434, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] Regulation of Pulmonary Graft-versus-Host Disease by IL-26+CD26+CD4 T Lymphocytes.2015
- Author(s)
  Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C.
- Journal Title
  
  J Immunol
  
  Volume: 194(8) Issue: 8 Pages: 3697-712
- DOI
  10.4049/jimmunol.1402785
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067
[Journal Article] Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma.2014
- Author(s)
  Yamamoto J, Ohnuma K, Hatano R, Okamoto T, Komiya E, Yamazaki H, Iwata S, Dang NH, Aoe K, Kishimoto T, Yamada T, Morimoto C.
- Journal Title
  
  Br J Cancer.
  
  Volume: Vol 110 Issue: 9 Pages: 2232-45
- DOI
  10.1038/bjc.2014.151
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation.2014
- Author(s)
  Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H.
- Journal Title
  
  Chembiochem.
  
  Volume: Vol 15 Issue: 6 Pages: 799-804
- DOI
  10.1002/cbic.201300762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells.2014
- Author(s)
  Komiya E, Ohnuma K, Yamazaki H, Hatano R, Iwata S, Okamoto T, Dang NH, Yamada T, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol 447 Issue: 4 Pages: 609-15
- DOI
  10.1016/j.bbrc.2014.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760
[Patent] 抗CD26抗体と免疫チェックポイント阻害剤との併用療法.2022
- Inventor(s)
  森本幾夫、波多野良、大沼圭、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07683
[Patent] 抗CD26抗体と免疫チェックポイント阻害剤との併用療法2022
- Inventor(s)
  森本幾夫, 波多野良, 大沼圭, 金子有太郎
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社, 学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗CD26抗体と免疫チェックポイント阻害剤との併用療法.2021
- Inventor(s)
  森本幾夫、波多野良、大沼圭、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-091761
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K07683
[Patent] 抗CD26抗体と免疫チェックポイント阻害剤との併用療法.2021
- Inventor(s)
  森本幾夫、波多野良、大沼圭、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-091761
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗癌剤への抵抗性改善剤.2021
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗癌剤への抵抗性改善剤.2021
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07683
[Patent] 抗癌剤への抵抗性改善剤2020
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-099449
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗癌剤への抵抗性改善剤2020
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-099449
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07683
[Patent] 免疫チェックポイント阻害剤.2019
- Inventor(s)
  大沼圭、森本幾夫、波多野良.
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-004480
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K10008
[Patent] 免疫チェックポイント阻害剤2019
- Inventor(s)
  大沼圭、森本幾夫、波多野良
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-004480
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗ヒトCD26モノクローナル抗体2018
- Inventor(s)
  森本幾夫、波多野良、山田健人、大沼圭
- Industrial Property Rights Holder
  学校法人順天堂，学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-049308
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗ヒトCD26モノクローナル抗体.2018
- Inventor(s)
  森本幾夫、波多野良、山田健人、大沼圭.
- Industrial Property Rights Holder
  学校法人順天堂、学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-049308
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K10008
[Patent] 抗ヒトCD26モノクローナル抗体.2018
- Inventor(s)
  森本幾夫、波多野良、山田健人、大沼圭.
- Industrial Property Rights Holder
  学校法人順天堂、学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-049308
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-26860760
[Patent] 抗ヒトIL-26抗体.2017
- Inventor(s)
  森本幾夫、波多野良、大沼圭、伊藤匠.
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231439
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-26860760
[Patent] 抗CD10抗体.2017
- Inventor(s)
  水谷奈津子、阿部雅明、松岡周二、樋野興夫、大辻奈穂美、波多野良.
- Industrial Property Rights Holder
  学校法人順天堂、日本抗体医薬株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K10008
[Patent] 抗ヒトIL-26抗体.2017
- Inventor(s)
  森本幾夫、波多野良、大沼圭、伊藤匠.
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231439
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K10008
[Patent] 抗ヒトIL-26抗体2017
- Inventor(s)
  森本幾夫、波多野良、大沼圭、伊藤匠
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231439
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗CD10抗体.2017
- Inventor(s)
  水谷奈津子、阿部雅明、松岡周二、樋野興夫、大辻奈穂美、波多野良.
- Industrial Property Rights Holder
  学校法人順天堂、日本抗体医薬株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-26860760
[Patent] 免疫抑制剤.2014
- Inventor(s)
  森本幾夫, 大沼圭, 波多野良.
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-199260
- Filing Date
  2014-09-29
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] Humanized anti-CD26 antibody suppresses the epithelial-mesenchymal transition of colorectal cancer cells.2023
- Author(s)
  岩尾憲明, 岩澤卓弥, 波多野良, 森本幾夫.
- Organizer
  第82回日本癌学会, 横浜, 2023年9月21日
- Data Source
  KAKENHI-PROJECT-23K27395
[Presentation] Functional Roles for CD26/DPP4 in LPS-induced Lung Injury in Mice2023
- Author(s)
  Sato S, Kawasaki T, Hatano R, Koyanagi Y, Takahashi Y, Ohnuma K, Morimoto C, Dudek SM, Tatsumi K, Suzuki T
- Organizer
  American Thoracic Society 2023 International Conference, Washington, DC, USA, 2023年5月19日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06501
[Presentation] Bleomycin-induced pulmonary fibrosis is attenuated in CD26/DPP4 deficient mice2023
- Author(s)
  Koyanagi Y, Kawasaki T, Kasuya Y, Hatano R, Suzuki T
- Organizer
  第63回日本呼吸器学会学術講演会, 東京, 2023年4月28日
- Data Source
  KAKENHI-PROJECT-23K06501
[Presentation] Functional Roles for CD26/DPP4 in Mouse Bleomycin-induced Pulmonary Fibrosis2023
- Author(s)
  Koyanagi Y, Kawasaki T, Kasuya Y, Hatano R, Takahashi Y, Sato S, Ohnuma K, Morimoto C, Tatsumi K, Suzuki T
- Organizer
  American Thoracic Society 2023 International Conference, Washington, DC, USA, 2023年5月19日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06501
[Presentation] Functional Roles for CD26/DPP4 in LPS-induced Lung Injury in Mice.2023
- Author(s)
  Sato S, Kawasaki T, Hatano R, Koyanagi Y, Takahashi Y, Ohnuma K, Morimoto C, Dudek SM, Tatsumi K, Suzuki T.
- Organizer
  American Thoracic Society 2023 International Conference, Washington, DC, USA, 2023年5月19日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27395
[Presentation] Humanized anti-CD26 antibody suppresses the epithelial-mesenchymal transition of colorectal cancer cells2023
- Author(s)
  岩尾憲明, 岩澤卓弥, 波多野良, 森本幾夫
- Organizer
  第82回日本癌学会, 横浜, 2023年9月21日
- Data Source
  KAKENHI-PROJECT-23K06501
[Presentation] Functional Roles for CD26/DPP4 in Mouse Bleomycin-induced Pulmonary Fibrosis.2023
- Author(s)
  Koyanagi Y, Kawasaki T, Kasuya Y, Hatano R, Takahashi Y, Sato S, Ohnuma K, Morimoto C, Tatsumi K, Suzuki T.
- Organizer
  American Thoracic Society 2023 International Conference, Washington, DC, USA, 2023年5月19日
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27395
[Presentation] IL-26 facilitates cartilage destruction and infiltration of inflammatory cells into synovium in a collagen induced arthritis model.2022
- Author(s)
  Shirakawa Y, Hatano R, Itoh T, Otsuka H, Okumura K, Morimoto C.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] IL-26 facilitates cartilage destruction and infiltration of inflammatory cells into synovium in a collagen induced arthritis model.2022
- Author(s)
  Shirakawa Y, Hatano R, Itoh T, Otsuka H, Okumura K, Morimoto C.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] CD26/dipeptidyl-peptidase IVは機械的かゆみの調節因子である.2021
- Author(s)
  古宮栄利子, 冨永光俊, 波多野良, 外山扇雅, 伊藤匠, 鎌田弥生, 本田耕太郎, 大沼圭, 森本幾夫, 高森建二.
- Organizer
  第26回日本病態プロテアーゼ学会, Web開催, 口頭
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] Mu-opioid ligand endomorphin induces alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  第46回日本研究皮膚科学会, Web開催, 口頭
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] Mu-opioid ligand endomorphin induces alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  第46回日本研究皮膚科学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Anti-interleukin-26 therapy for the control of chronic inflammation in GVHD.2021
- Author(s)
  Hatano R, Otsuka H, Itoh T, Saeki H, Yamamoto A, Shirakawa Y, Iyama S, Iwao N, Sato T, Yamada T, Morimoto C, Ohnuma K.
- Organizer
  第83回日本血液学会, Web開催, 口頭
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] CD26/dipeptidyl-peptidase IVは機械的かゆみの調節因子である.2021
- Author(s)
  古宮栄利子, 冨永光俊, 波多野良, 外山扇雅, 伊藤匠, 鎌田弥生, 本田耕太郎, 大沼圭, 森本幾夫, 高森建二.
- Organizer
  第26回日本病態プロテアーゼ学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] CD26/DPPIV regulates mechanical alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  11th World Congress on Itch (WCI), Web開催, 口頭
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] CD26/DPPIV regulates mechanical alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  11th World Congress on Itch (WCI), 口頭発表, Web開催
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Anti-interleukin-26 therapy for the control of chronic inflammation in GVHD.2021
- Author(s)
  Hatano R, Otsuka H, Itoh T, Saeki H, Yamamoto A, Shirakawa Y, Iyama S, Iwao N, Sato T, Yamada T, Morimoto C, Ohnuma K.
- Organizer
  第83回日本血液学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Endomorphin preferentially induces mechanical alloknesis under the control of DPPIV enzyme.2020
- Author(s)
  Eriko Komiya, Ryo Hatano, Takumi Itoh, Kotaro Honda, Yayoi Kamata, Sumika Toyama, Catharina Sagita Moniaga, Haruna Otsuka, Nobuaki Takahashi, Kei Ohnuma, Mitsutoshi Tominaga, Chikao Morimoto, Kenji Takamori.
- Organizer
  The 45th Annual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Endomorphin preferentially induces mechanical alloknesis under the control of DPPIV enzyme.2020
- Author(s)
  Eriko Komiya, Ryo Hatano, Takumi Itoh, Kotaro Honda, Yayoi Kamata, Sumika Toyama, Catharina Sagita Moniaga, Haruna Otsuka, Nobuaki Takahashi, Kei Ohnuma, Mitsutoshi Tominaga, Chikao Morimoto, Kenji Takamori.
- Organizer
  第45回日本研究皮膚科学会、WEB開催
- Data Source
  KAKENHI-PROJECT-20K07683
[Presentation] Possible role for CD26/DPPIV in regulating mechanical itch (Alloknesis).2019
- Author(s)
  Komiya E, Hatano R, Itoh T, Otsuka H, Kamata Y, Honda K, Toyama S, Moniaga CS, Ohnuma K, Tominaga M, Morimoto C, Takamori K.
- Organizer
  28th European Academy of Dermatology and Venereology (EADV) Congress, Madrid, Spain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] Possible regulation of mechanical itch by CD26/DPPIV.2019
- Author(s)
  Komiya E, Hatano R, Itoh T, Otsuka H, Kamata Y, Honda K, Toyama S, Moniaga CS, Ohnuma K, Tominaga M, Morimoto C, Takamori K.
- Organizer
  10th World Congress on Itch (WCI), Sydney, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 加齢皮膚で誘発される機械的かゆみ調節機構の解明2019
- Author(s)
  古宮栄利子、冨永光俊、波多野良、伊藤匠、大塚春奈、本田耕太郎、外山扇雅、鎌田弥生、大沼圭、森本幾夫、髙森建二
- Organizer
  第15回加齢皮膚医学研究会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/dipeptidyl-peptidase IVは機械的かゆみの抑制因子である.2019
- Author(s)
  古宮栄利子, 波多野良, 冨永光俊, 伊藤匠, 鎌田弥生, 本田耕太郎, 外山扇雅, カタリナサギタモニアガ, 大沼圭, 森本幾夫, 高森建二.
- Organizer
  第24回日本病態プロテアーゼ学会, 岐阜
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 加齢皮膚で誘発される機械的かゆみ調節機構の解明.2019
- Author(s)
  古宮栄利子、冨永光俊、波多野良、伊藤匠、大塚春奈、本田耕太郎、外山扇雅、鎌田弥生、大沼圭、森本幾夫、高森建二.
- Organizer
  第15回加齢皮膚医学研究会、くまもと森都心プラザ(熊本県熊本市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] CD26/DPPIV regulates mechanical itch by enzymatic degradation of mu-opioid receptor ligands.2019
- Author(s)
  Komiya E, Hatano R, Itoh T, Otsuka H, Ohnuma K, Tominaga M, Morimoto C, Takamori K.
- Organizer
  24th World Congress of Dermatology (WCD), Milan, Italy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] CD26分子はDPPⅣ酵素活性によって乾癬のかゆみを調節する2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、大沼圭、冨永光俊、森本幾夫、髙森建二
- Organizer
  第33回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討.2018
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫.
- Organizer
  第40回日本造血細胞移植学会、札幌市教育文化会館(北海道札幌市)
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] 全身性エリテマトーデスのステロイド減量困難例におけるCD26陰性T細胞サブセットの増加について2018
- Author(s)
  波多野良、大沼圭、石井智徳、伊藤匠、岩田哲史、奥村康、関川巖、森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 機械的かゆみの調節メカニズムの解明.2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、松田浩則、須賀康、大沼圭、冨永光俊、森本幾夫、高森建二.
- Organizer
  第82回日本皮膚科学会東京支部、ザ・プリンスパークタワー東京(東京都港区)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 難治性自己免疫疾患における新規炎症性サイトカインIL-26の役割と分子標的療法の開発2018
- Author(s)
  伊藤匠、波多野良、岩田哲史、大沼圭、森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIVはエンドモルフィンによる機械的かゆみを制御する.2018
- Author(s)
  古宮栄利子、波多野良、伊藤匠、松田浩則、大沼圭、森本幾夫、冨永光俊、高森建二.
- Organizer
  第28回国際痒みシンポジウム、経団連会館カンファレンス(東京都千代田区)
- Invited
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 乾癬における新規炎症性サイトカインIL-26の役割と分子標的療法の開発2018
- Author(s)
  伊藤匠、波多野良、古宮栄利子、大塚春奈、冨永光俊、髙森建二、森本幾夫、大沼圭
- Organizer
  第33回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD.2018
- Author(s)
  Ryo Hatano, Haruna Otsuka, Eriko Komiya, Takumi Itoh, Noriaki Iwao, Taketo Yamada, Chikao Morimoto, Kei Ohnuma.
- Organizer
  第80回日本血液学会、大阪国際会議場(大阪府大阪市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD.2018
- Author(s)
  Ryo Hatano, Haruna Otsuka, Eriko Komiya, Takumi Itoh, Noriaki Iwao, Taketo Yamada, Chikao Morimoto, KeiOhnuma.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 乾癬における新規炎症性サイトカインIL-26の役割と分子標的療法の開発.2018
- Author(s)
  伊藤匠、波多野良、古宮栄利子、大塚春奈、冨永光俊、高森建二、森本幾夫、大沼圭.
- Organizer
  第33回日本乾癬学会、松山全日空ホテル(愛媛県松山市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 機械的かゆみの調節メカニズムの解明2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、松田浩則、須賀康、大沼圭、冨永光俊、森本幾夫、髙森建二
- Organizer
  第82回日本皮膚科学会東京支部
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26分子はDPPIV酵素活性によって乾癬のかゆみを調節する.2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、大沼圭、森本幾夫、冨永光俊、高森建二.
- Organizer
  第33回日本乾癬学会、松山全日空ホテル(愛媛県松山市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 難治性自己免疫疾患における新規炎症性サイトカインIL-26の役割と分子標的療法の開発.2018
- Author(s)
  伊藤匠、波多野良、岩田哲史、大沼圭、森本幾夫.
- Organizer
  第62回日本リウマチ学会、東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 全身性エリテマトーデスのステロイド減量困難例におけるCD26陰性T細胞サブセットの増加について.2018
- Author(s)
  波多野良、大沼圭、石井智徳、伊藤匠、岩田哲史、奥村康、関川巖、森本幾夫.
- Organizer
  第62回日本リウマチ学会、東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2018
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫
- Organizer
  第40回日本造血細胞移植学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討.2018
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫.
- Organizer
  第40回日本造血細胞移植学会、札幌市教育文化会館(北海道札幌市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] CD26/DPPⅣはエンドモルフィンによる機械的かゆみを制御する2018
- Author(s)
  古宮栄利子、波多野良、伊藤匠、松田浩則、大沼圭，森本幾夫、冨永光俊、髙森建二
- Organizer
  第28回国際痒みシンポジウム
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIV regulates mechanical itch in a mechanistically distinct manner from chemical itch2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  第42回日本研究皮膚科学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 全身性エリテマトーデスのステロイド治療抵抗性とCD26陰性T細胞サブセットとの関係性について.2017
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川巖、森本幾夫.
- Organizer
  第61回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIV regulates mechanical itch in a mechanistically distinct manner from chemical itch.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  第42回日本研究皮膚科学会、高知市文化プラザかるぽーと(高知県高知市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 全身性エリテマトーデスのステロイド治療抵抗性とCD26陰性T細胞サブセットとの関係性について.2017
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川巖、森本幾夫.
- Organizer
  第61回日本リウマチ学会、福岡国際会議場(福岡県福岡市)
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] The regulation of pruritus in psoriasis and atopic dermatitis -a possible role for CD26/DPPIV.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Taketo Yamada, Yasushi Suga, Utako Kimura, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  9th World Congress on Itch, Novotel Centrum, Wroclaw, Poland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model of imiquimod-induced psoriasis.2017
- Author(s)
  Takumi Itoh, Ryo Hatano, Haruna Otsuka, Noriaki Iwao, Satoshi Iwata, Taketo Yamada, Chikao Morimoto.
- Organizer
  第46回日本免疫学会、仙台国際センター(宮城県仙台市)
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] The regulation of pruritus in psoriasis and atopic dermatitis-a possible role for CD26/DPPIV.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Taketo Yamada, Yasushi Suga, Utako Kimura, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  9th World Congress on Itch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIV regulates mechanical itch in a mechanistically distinct manner from chemical itch.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  第42回日本研究皮膚科学会、高知市文化プラザかるぽーと(高知県高知市)
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] The regulation of pruritus in psoriasis and atopic dermatitis -a possible role for CD26/DPPIV.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Taketo Yamada, Yasushi Suga, Utako Kimura, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  9th World Congress on Itch, Novotel Centrum, Wroclaw, Poland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] 全身性エリテマトーデスのステロイド治療抵抗性とCD26陰性T細胞サブセットとの関係性について.2017
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川巖、森本幾夫.
- Organizer
  第61回日本リウマチ学会、福岡国際会議場(福岡県福岡市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model of imiquimod-induced psoriasis.2017
- Author(s)
  Takumi Itoh, Ryo Hatano, Haruna Otsuka, Noriaki Iwao, Satoshi Iwata, Taketo Yamada, Chikao Morimoto.
- Organizer
  第46回日本免疫学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model of imiquimod-induced psoriasis.2017
- Author(s)
  Takumi Itoh, Ryo Hatano, Haruna Otsuka, Noriaki Iwao, Satoshi Iwata, Taketo Yamada, Chikao Morimoto.
- Organizer
  第46回日本免疫学会、仙台国際センター(宮城県仙台市)
- Data Source
  KAKENHI-PROJECT-17K10008
[Presentation] CD26/DPPIV-mediated regulation of pruritus in psoriasis.2016
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Taketo Yamada, Mitsutoshi Tominag, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  第41回研究皮膚科学会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-11-09
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] CD26陽性T細胞サブセットに基づく全身性エリテマトーデスの病態解析2016
- Author(s)
  波多野良
- Organizer
  第60回日本リウマチ学会
- Place of Presentation
  横浜(会場：パシフィコ横浜)
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 乾癬においてCD26/DPPIVはsubstance Pの切断を促進してかゆみを調節する.2016
- Author(s)
  古宮栄利子, 波多野良, 大塚春奈, 伊藤匠, 山田健人, 冨永光俊, 高森建二, 大沼圭, 森本幾夫.
- Organizer
  第31回日本乾癬学会
- Place of Presentation
  ホテル東日本宇都宮(栃木県宇都宮市)
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] CD26陽性T細胞サブセットに基づく全身性エリテマトーデスの病態解析.2016
- Author(s)
  波多野良, 大沼圭, 石井智徳, 岩田哲史, 奥村康, 関川巖, 森本幾夫.
- Organizer
  第60回日本リウマチ学会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] Anti-interleukin-26 therapy for lung fibrosis of GVHD.2015
- Author(s)
  Ryo Hatano, Taketo Yamada, Haruna Otsuka, Eriko Komiya, Noriaki Iwao, Ko Okumura, Chikao Morimoto, Kei Ohnuma.
- Organizer
  第77回日本血液学会.
- Place of Presentation
  ホテル日航金沢(石川県金沢市)
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] T細胞共刺激分子CD26に基づく全身性エリテマトーデスの病態および疾患活動性の新規バイオマーカーの探索.2015
- Author(s)
  波多野良, 大沼圭, 岩田哲史, 石井智徳, 関川巖, 森本幾夫.
- Organizer
  第59回日本リウマチ学会.
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] DPP4阻害薬の服用によって誘発される多関節症とそのバイオマーカー.
- Author(s)
  大沼圭, 斎藤辰彦, 波多野良, 岩田哲史, 鈴木博史, 森本幾夫.
- Organizer
  第58回日本リウマチ学会.
- Place of Presentation
  グランドプリンスホテル新高輪 (東京都港区)
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26860760
[Presentation] IL-10産生誘導によるCD26共刺激経路のnegative feedback機構の解析.
- Author(s)
  波多野良, 大沼圭, 岩田哲史, 石井智徳, 関川巖, 森本幾夫.
- Organizer
  第58回日本リウマチ学会.
- Place of Presentation
  グランドプリンスホテル新高輪 (東京都港区)
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26860760

1. Morimoto Chikao (30119028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
2. 岩田哲史 (00396871)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. 大沼圭 (10396872)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
4. 岩尾憲明 (00309139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 伊藤匠 (80811835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISHII Tomonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. SEKIGAWA Iwao

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 川崎剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 山田健人

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 山田幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 古宮栄利子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 岸裕幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatano Ryo 波多野 良

Research Projects

Research Products

Co-Researchers

ヒト化抗CD26抗体を用いた大腸癌の転移病巣に対する新規治療法の開発

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Molecular understanding of an innovative therapy for chronic inflammatory diseases targeting human Th17 cytokine IL-26

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Basic research for the development of novel therapy targeting neutrophils and organ fibrosis to regulate chronic inflammationPrincipal Investigator

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Molecular understanding of tumor immunology of malignant pleural mesothelioma targeting human CD26/DPPIV molecule.Principal Investigator

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Understanding of detailed pathology and development of novel molecular targeted therapy for the treatment of refractory chronic inflammatory diseases based on the inflammatory cytokine IL-26

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Development of a novel therapy for refractory inflammatory diseases targeting an inflammatory cytokine IL-26Principal Investigator

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Molecular understanding of CD26-mediated immune regulatory mechanism and development of novel molecular targeted therapy for the treatment of refractory autoimmune diseases

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Analysis of CD8+CD26-positive/negative T cell subsets for the development of an innovative therapy and elucidating the pathophysiology of refractory autoimmune diseasesPrincipal Investigator

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[Book] Advances in Medicine and Biology2019

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[Book] Advances in Medicine and Biology2018

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[Book] Advances in Medicine and Biology2018

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[Book] Advances in Medicine and Biology2018

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[Book] Horizons in Cancer Research2017

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[Book] Horizons in Cancer Research.2017

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Hatano Ryo 波多野良