Oki Kenji 沖健司

… Alternative Names

沖健司オキケンジ

OKI Kenji 沖健司

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Researcher Number	30638995
Other IDs
Affiliation (Current)	2022: 広島大学, 病院(医), 講師 2022: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他
Affiliation (based on the past Project Information) *help	2021: 広島大学, 病院(医), 講師 2018 – 2019: 広島大学, 病院(医), 講師 2016 – 2017: 広島大学, 病院(医), 助教 2016: 広島大学, 病院(医), 病院助教 2015: 広島大学, 大学病院, その他 2013 – 2014: 広島大学, 大学病院, 病院助教 2012: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, その他
Review Section/Research Field	Principal Investigator Endocrinology / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Urology
Keywords	Principal Investigator アルドステロン / アンギオテンシンII / 原発性アルドステロン症 / 高血圧 / 副腎皮質 / G蛋白共役型受容体 / アルドステロン合成酵素 / 細胞内カルシウム伝達 / G蛋白共役受容体 / カルシウムシグナル … More / 二次性高血圧 / CALN1 / シグナル伝達 / 遺伝子変異 / 蛋白発現調節 … More Except Principal Investigator アルドステロン / アルドステロン産生腺腫 / 原発性アルドステロン症 / アルドステロン合成酵素 / アルドステロン産生細胞クラスター (APCC) / 体細胞変異 / イオンチャネル / イオンポンプ (イオントランスポーター) / CYP11B2 / APCC / pAATL / アルドステロン産生細胞クラスター / KCNJ5 / 副腎皮質 / 次世代シーケンサー Less

The clarification of aldosterone production machinery and the identification of therapeutic factors based on the posttranscriptional regulationPrincipal Investigator
- Principal Investigator
  
  沖健司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
Aldosterone production mechanisms mediated by ER calcium ion regulation.Principal Investigator
- Principal Investigator
  
  OKI KENJI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Hiroshima University
Ealucidation of progression from aldosterone-producing cell cluster leading to aldosterone-producing adenoma
- Principal Investigator
  
  Nishimoto Koshiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Saitama Medical University
  Keio University
The novel mechanism of aldosterone production in aldosterone-producing adenomaPrincipal Investigator
- Principal Investigator
  
  OKI KENJI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Hiroshima University
The study of aldosterone production machinery by angiotensin II metabolitePrincipal Investigator
- Principal Investigator
  
  OKI Kenji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Endocrinology
- Research Institution
  Hiroshima University
  Department of Clinical Research, National Hospital Organization Kure Medical Center

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Endoplasmic Reticulum Chaperone Calmegin Is Upregulated in Aldosterone-Producing Adenoma and Associates With Aldosterone Production.2020
- Author(s)
  Itcho K, Oki K, Gomez-Sanchez CE, Gomez-Sanchez EP, Ohno H, Kobuke K, Nagano G, Yoshii Y, Baba R, Hattori N, Yoneda M.
- Journal Title
  
  Hypertension
  
  Volume: 75 Pages: 492-499
- DOI
  10.1161/hypertensionaha.119.14062
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17972, KAKENHI-PROJECT-17K09883
[Journal Article] A Rare Case of IgG4-Related Disease Presenting as a Unilateral Severe Dacryoadenitis Complicated by Hypophysitis and Hypertrophic Pachymeningitis.2020
- Author(s)
  Yoshida Y, Kondo T, Hosokawa Y, Oki K, Yukawa K, Araki K, Kohno H, Kuranobu T, Tokunaga T, Oi K, Sugimoto T, Oda K, Nojima T, Hirata S, Sugiyama E.
- Journal Title
  
  J Clin Rheumatol
  
  Volume: -
- DOI
  10.1097/rhu.0000000000000989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.2019
- Author(s)
  Kishimoto S, Oki K, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Takaeko Y, Kihara Y, Chayama K, Goto C, Aibara Y, Yusoff FM, Nakashima A, Noma K, Liao JK, Higashi Y.
- Journal Title
  
  J Hypertens
  
  Volume: 37 Pages: 1083-1095
- DOI
  10.1097/hjh.0000000000001989
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition.2019
- Author(s)
  Kobuke K, Oki K, Gomez-Sanchez CE, Ohno H, Itcho K, Yoshii Y, Yoneda M, Hattori N.
- Journal Title
  
  J Steroid Biochem Mol Biol
  
  Volume: 185 Pages: 137-141
- DOI
  10.1016/j.jsbmb.2018.08.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency2019
- Author(s)
  Maruhashi T, Amioka M, Kishimoto S, Ikenaga H, Oki K, Ishida M, Kihara Y, Higashi Y.
- Journal Title
  
  Internal Medicine
  
  Volume: 58 Issue: 21 Pages: 3107-3111
- DOI
  10.2169/internalmedicine.2327-18
- NAID
  130007740769
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Alteration of gut microbiota by a Westernized lifestyle and its correlation with insulin resistance in non-diabetic Japanese men.2019
- Author(s)
  Yamashita M, Okubo H, Kobuke K, Ohno H, Oki K, Yoneda M, Tanaka J, Hattori N.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 10 Pages: 1463-1470
- DOI
  10.1111/jdi.13048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Associations of nutrient intakes with obesity and diabetes mellitus in the longitudinal medical surveys of Japanese Americans.2019
- Author(s)
  Sugihiro T, Yoneda M, Ohno H, Oki K, Hattori N.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 10 Pages: 1229-1236
- DOI
  10.1111/jdi.13010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Calneuron 1 Increased Ca2+in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing AdenomaNovelty and Significance2018
- Author(s)
  Kobuke K, Oki K, Gomez-Sanchez CE, Gomez-Sanchez EP, Ohno H, Itcho K, Yoshii Yoko, Yoneda M, Hattori, N.
- Journal Title
  
  Hypertension
  
  Volume: 71 Pages: 125-133
- DOI
  10.1161/hypertensionaha.117.10205
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-17K16166
[Journal Article] Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma2018
- Author(s)
  Kobuke K, Oki K, Gomez-Sanchez CE, Ohno H, Itcho K, Yoshii Y, Yoneda M, Hattori N.
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 103 Pages: 965-971
- DOI
  10.1210/jc.2017-01996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-17K16166, KAKENHI-PROJECT-17H06894
[Journal Article] Aberrant G protein-receptor expression is associated with DNA methylation in aldosterone-producing adenoma2018
- Author(s)
  Itcho K, Oki K, Kobuke K, Yoshii Y, Ohno H, Yoneda M, Hattori N.
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 461 Pages: 100-104
- DOI
  10.1016/j.mce.2017.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-17K16166, KAKENHI-PROJECT-17H06894
[Journal Article] Measurement of midnight ACTH levels is useful for the evaluation of midnight cortisol levels.2018
- Author(s)
  Baba R, Oki K, Kobuke K, Itcho K, Okubo H, Ohno H, Yoneda M, Hattori N.
- Journal Title
  
  Steroids
  
  Volume: 140 Pages: 179-184
- DOI
  10.1016/j.steroids.2018.10.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Microvascular endothelial function is impaired in patients with idiopathic hyperaldosteronism.2018
- Author(s)
  Kishimoto S, Matsumoto T, Oki K, Maruhashi T, Kajikawa M, Matsui S, Hashimoto H, Kihara Y, Yusoff FM, Higashi Y.
- Journal Title
  
  Hypertens Res
  
  Volume: 41 Pages: 932-938
- DOI
  10.1038/s41440-018-0093-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Effect of miglitol on the suppression of nonalcoholic steatohepatitis development and improvement of the gut environment in a rodent model2017
- Author(s)
  Kishida Yumi, Okubo Hirofumi, Ohno Haruya, Oki Kenji, Yoneda Masayasu
- Journal Title
  
  J Gastroenterol
  
  Volume: Epub ahead of print Pages: 1180-1191
- DOI
  10.1007/s00535-017-1331-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19538, KAKENHI-PROJECT-17K09883
[Journal Article] Association between Serum Elaidic Acid Concentration and Insulin Resistance in Two Japanese Cohorts with Different Lifestyles2017
- Author(s)
  Itcho K, Yoshii Y, Ohno H, Oki K, Shinohara M, Irino Y, Toh R, Ishida T, Hirata KI, Yoneda M.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 24 Issue: 12 Pages: 1206-1214
- DOI
  10.5551/jat.39164
- NAID
  130006235272
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] Increased Calcium Ion Levels Following Systemic Circulation After the Selective Arterial Calcium Injection Test2017
- Author(s)
  Egusa G, Oki K, Yoshii Y, Kubota M, Okubo H, Ohno H, Kajiwara K, Awai K, Yoneda M.
- Journal Title
  
  Pancreas
  
  Volume: 46
- DOI
  10.1097/mpa.0000000000000803
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program2017
- Author(s)
  Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, Sun W, Aoyama T, Hirota Y, Ohno H, Oki K, Yoneda M, White AP, Tseng YH, Cypess AM, Larsen TJ, Jespersen NZ, Scheele C, Tsutsumi S, Aburatani H, Yamauchi T, Kadowaki T
- Journal Title
  
  Nature Cell Biology
  
  Volume: 19(9) Pages: 1081-1092
- DOI
  10.1038/ncb3590
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09818, KAKENHI-PROJECT-17K09883, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-26000012
[Journal Article] Immunohistochemistry of aldosterone synthase leads the way to the pathogenesis of primary aldosteronism.2017
- Author(s)
  Nishimoto, K., Koga, M., Seki, T., Oki, K., Gomez-Sanchez, E.P., Gomez-Sanchez, C.E., Naruse, M., Sakaguchi, T., Morita, S., Kosaka, T., Oya, M., Ogishima, T., Yasuda, M., Suematsu, M., Kabe, T., Omura, M., Nishikawa, T., Mukai, K.
- Journal Title
  
  Mol Cell Endocrinol.
  
  Volume: 441 Pages: 124-133
- DOI
  10.1016/j.mce.2016.10.014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461387, KAKENHI-PROJECT-26860707, KAKENHI-PROJECT-15K07011, KAKENHI-PROJECT-15K10650
[Journal Article] Westernization of lifestyle affects quantitative and qualitative changes in adiponectin2017
- Author(s)
  Kubota M, Yoneda M, Maeda N, Ohno H, Oki K, Funahashi T, Shimomura I, Hattori N.
- Journal Title
  
  Cardiovasc Diabetol
  
  Volume: 16 Pages: 83-83
- DOI
  10.1186/s12933-017-0565-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09883
[Journal Article] YPEL4 modulates HAC15 adrenal cell proliferation and is associated with tumor diameter.2016
- Author(s)
  Oki K, Plonczynski MW, Gomez-Sanchez EP, Gomez-Sanchez CE.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 434 Pages: 93-98
- DOI
  10.1016/j.mce.2016.06.022
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Journal Article] Gonadotropin-Releasing Hormone Stimulate Aldosterone Production in a Subset of Aldosterone-Producing Adenoma.2016
- Author(s)
  Kishimoto R, Oki K, Yoneda M, Gomez-Sanchez CE, Ohno H, Kobuke K, Itcho K, Kohno N.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 95
- DOI
  10.1097/md.0000000000003659
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Journal Article] Hypothalamic-pituitary-adrenal axis activity is associated with the prevalence of chronic kidney disease in diabetic patients2016
- Author(s)
  Asao T, Oki K, Yoneda M, Tanaka J, Kohno N.
- Journal Title
  
  Endocrine Journal
  
  Volume: 63 Issue: 2 Pages: 119-126
- DOI
  10.1507/endocrj.ej15-0360
  10.1507/endocrj.EJ15-0360
- NAID
  130005127189
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Journal Article] Hypomethylation of CYP11B2 in Aldosterone-Producing Adenoma.2016
- Author(s)
  Yoshii Y, Oki K, Gomez-Sanchez CE, Ohno H, Itcho K, Kobuke K, Yoneda M.
- Journal Title
  
  Hypertension
  
  Volume: 68 Pages: 1432-1437
- DOI
  10.1161/hypertensionaha.116.08313
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Journal Article] Minireview : potassium channels and aldosterone dysregulation : is primary aldosteronism a potassium channelopathy?2014
- Author(s)
  Gomez-Sanchez CE, Oki K
- Journal Title
  
  Endocrinology
  
  Volume: 155 Pages: 47-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Significantly high level of late-night free cortisol to creatinine ratio in urine specimen in patients with subclinical Cushing's syndrome2013
- Author(s)
  Shiwa T, Oki K
- Journal Title
  
  Clin Endocrinol (Oxf)
  
  Volume: 79 Pages: 617-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Angiotensin II and III Metabolism and Effects on Steroid Production in the HAC15 Human Adrenocortical Cell Line.2013
- Author(s)
  Kenji Oki
- Journal Title
  
  Endocrinology
  
  Volume: 154(1): Pages: 214-21
- DOI
  10.1210/en.2012-1557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310041, KAKENHI-PROJECT-24890308, KAKENHI-PROJECT-25340047
[Journal Article] Angiotensin II and III metabolism and effects on steroid production in the HAC15 Human Adrenocortical Cell line2013
- Author(s)
  Oki K
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 214-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Minireview: potassium channels and aldosterone dysregulation: is primary aldosteronism a potassium channelopathy?2013
- Author(s)
  Gomez-Sanchez CE, Oki K.
- Journal Title
  
  Endocrinology
  
  Volume: 155 Pages: 47-55
- DOI
  10.1210/en.2013-1733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Potassium Channel Mutant KCNJ5 T158A Expression in HAC-15 Cells Increases Aldosterone Synthesis2012
- Author(s)
  Oki K
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 1774-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Influence of adrenal subclinical hypercortisolism on hypertension in patients with adrenal incidentaloma.2012
- Author(s)
  Oki K, et al.
- Journal Title
  
  Exp Clin Endocrinol Diabetes
  
  Volume: 120 Pages: 244-247
- DOI
  10.1055/s-0032-1301896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Influence of adrenal subclinical hypercortisolism on hypertension in patients with adrenal incidentaloma2012
- Author(s)
  Oki K
- Journal Title
  
  Exp Clin Endocrinol Diabetes
  
  Volume: 120 Pages: 244-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis.2012
- Author(s)
  Oki K, et al.
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 1774-1782
- DOI
  10.1210/en.2011-1733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line.2012
- Author(s)
  Oki K, et al.
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 4328-4335
- DOI
  10.1210/en.2012-1241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Journal Article] The potassium channel Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line2012
- Author(s)
  Oki K
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 4228-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] ATP1A1 mutation stimulates adrenal cell proliferation via vitamin D receptor signal induced by DNA demethylation2019
- Author(s)
  Yuta Nanao, Kenji Oki, Celso E. Gomez-Sanchez, Kazuhiro Kobuke, Kiyotaka Itcho, Ryuta Baba, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  44th Meeting of the International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Molecular chaperone CLGN associates with aldosterone production in APA and APCC.2019
- Author(s)
  Kiyotaka Itcho, Kenji Oki, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Kazuhiro Kobuke, Ryuta Baba, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  44th Meeting of the International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 分子シャペロンCLGNはアルドステロン産生腫瘍に特異的に発現しアルドステロン合成に関与する2019
- Author(s)
  一町澄宜, 沖健司, 馬場隆太, 小武家和博, 大久保博史, 大野晴也, 米田真康
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] ER chaperone calmegin is upregulated in aldosterone-producing adenoma and associates with aldosterone production2019
- Author(s)
  Kenji Oki, Kiyotaka Itcho, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Kazuhiro Kobuke, Ryuta Baba, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  Progress in Primary Aldosteronisum 6
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Ouabain induced aldosterone production and cell proliferation in ATP1A1 mutated aldosterone-producing adenoma2019
- Author(s)
  Kazuhiro Kobuke, Kenji Oki, Kiyotaka Itcho, Ryuta Baba, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  44th Meeting of the International Aldosterone Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 夜間ACTH高値が副腎性サブクリニカルクッシング症候群診断に与える影響2019
- Author(s)
  馬場隆太, 沖健司, 児玉尭也, 一町澄宜, 小武家和博, 長野学, 大久保博史, 大野晴也, 米田真康
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 副腎静脈サンプリングにおける最適な局在判定基準は2019
- Author(s)
  沖健司
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] ATP1A1変異によるアルドステロン産生腺腫増殖機構の解明2019
- Author(s)
  小武家和博, 沖健司, 馬場隆太, 一町澄宜, 長野学, 大久保博史, 大野晴也, 米田真康
- Organizer
  第92回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 分子シャペロンCLGNはアルドステロン産生腫瘍において発現上昇しアルドステロン合成を調節する2018
- Author(s)
  一町澄宜，沖健司，小武家和博，大野晴也，米田真康
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Molecular chaperone Calmegin is up-regulated in aldosterone-producing adenoma and associates with aldosterone production2018
- Author(s)
  Kiyotaka Itcho, Kenji Oki, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Kazuhiro Kobuke, Ryuta Baba, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  43th Meeting of the International Aldosterone Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Angiotensin 1-7 repress Angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition2018
- Author(s)
  Ryuta Baba, Kenji Oki, Kiyotaka Itcho, Kazuhiro Kobuke, Haruya Ohno, Masayasu Yoneda, Noboru Hattori
- Organizer
  43th Meeting of the International Aldosterone Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 分子生物学的解析から原発性アルドステロン症の成因に迫る2018
- Author(s)
  沖健司
- Organizer
  第28回臨床内分泌代謝Update
- Invited
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Ca2+ Binding Protein, Calneuron 1, Increased Ca2+ in Endoplasmic Reticulum and Aldosterone Production in Aldosterone-producing Adenoma2017
- Author(s)
  Kazuhiro Kobuke, Kenji Oki, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Kiyotaka Itcho, Yoko Yoshii, Haruya Ohno, Masayasu Yoneda
- Organizer
  42nd Meeting of the International Aldosterone Conference
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2017-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン産生腺腫におけるステロイド合成酵素のエピジェネティック調節機構2017
- Author(s)
  吉井陽子、沖健司、小武家和博、一町澄宜、大野晴也、米田真康
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] The regulation of PCP4 transcription via DNA methylation in aldosterone-producing adenoma2017
- Author(s)
  Kiyotaka Itcho, Kenji Oki, Celso E. Gomez-Sanchez, Kazuhiro Kobuke, Yoko Yoshii, Haruya Ohno, Masayasu Yoneda
- Organizer
  42nd Meeting of the International Aldosterone Conference
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2017-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] APAとSubCSを合併した両側副腎腫瘍の1例2017
- Author(s)
  岡田康平、一町澄宜、沖健司、馬場隆太、江草玄太郎、小武家和博、大久保博史、大野晴也、米田真康
- Organizer
  第27回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 新基準に基づく原発性アルドステロン症の局在診断への影響2017
- Author(s)
  小根森陽子、沖健司、江草玄太郎、岸田祐美、吉井陽子、森田好美、小武家和博、長野学、一町澄宜、久保田益亘、大久保博史、大野晴也、米田真康
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Aldosterone Production via Endoplasmic Reticulum Function in Aldosterone-producing Adenoma2017
- Author(s)
  Kenji Oki, Kazuhiro Kobuke, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Kiyotaka Itcho, Yoko Yoshii, Haruya Ohno, Masayasu Yoneda, Noboru Hattori.
- Organizer
  Hypertension Forum of Western Great Wall of China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 原発性アルドステロン症の局在診断における副腎静脈サンプリングの後ろ向き検討．2017
- Author(s)
  沖健司，久保田益亘，吉井陽子，江草玄太郎，岸本真治，池永寛樹，大久保博史，大野晴也，米田真康．
- Organizer
  第114回日本内科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] Ca2+結合タンパクcalneuron1を介したアルドステロン合成調節機構2017
- Author(s)
  小武家和博、一町澄宜、吉井陽子、沖健司、大野晴也、米田真康
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] 対側にコルチゾール産生腫瘍を合併したアルドステロン産生腫瘍の1例2017
- Author(s)
  木村文香、馬場隆太、沖健司、山本祐太郎、江草玄太郎、小武家和博、大久保博史、大野晴也、米田真康
- Organizer
  第117回日本内科学会中国地方会
- Data Source
  KAKENHI-PROJECT-17K09883
[Presentation] The effects of Angiotensin II metabolites on aldosterone production in the HAC15 human adrenocortical cell line2017
- Author(s)
  Yoko Yoshii, Kenji Oki, Kiyotaka Itcho, Kazuhiro Kobuke, Haruya Ohno, Masayasu Yoneda
- Organizer
  42nd Meeting of the International Aldosterone Conference
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2017-03-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン合成に関わるエピジェネティック制御機構2016
- Author(s)
  沖健司
- Organizer
  第24回日本ステロイドホルモン学会学術集会
- Place of Presentation
  大分
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン産生腺腫におけるステロイド合成酵素のエピジェネティック調節機構2016
- Author(s)
  吉井陽子、沖健司、小武家和博、一町澄宣、大野晴也、米田真康
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン産生腺腫におけるGNRHRを介したアルドステロン合成機構2016
- Author(s)
  沖健司、一町澄宜、小武家和博、吉井陽子、前田修作、大野晴也、米田真康
- Organizer
  第23回日本ステロイドホルモン学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2016-01-15
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] DNA hypo-methylation of Aldosterone synthesis (CYP11B2) in aldosterone producing adenoma, but not regulated by somatic mutations of adenoma.2016
- Author(s)
  Yoko Yoshii, Kenji Oki, Celso E. Gomez-Sanchez, Haruya Ohno, Kiyotaka Itcho, Kazuhiro Kobuke, Masayasu Yoneda
- Organizer
  International Society of Hypertension 2016 satellite symposium Renin-angiotensin-aldosterone system
- Place of Presentation
  Tokyo
- Year and Date
  2016-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン産生腺腫におけるステロイド合成酵素のエピジェネティック調節機構2016
- Author(s)
  吉井陽子、沖健司、小武家和博、一町澄宜、前田修作、大野晴也、米田真康、河野修興
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  京都
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] APA及び遺伝子変異に基づくステロイド合成酵素のDNAメチル化解析2016
- Author(s)
  吉井陽子、沖健司、一町澄宜、小武家和博、久保田益亘、大久保博史、大野晴也、米田真康
- Organizer
  第26回臨床内分泌代謝Update
- Place of Presentation
  大宮
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アンギオテンシンII代謝産物によるアルドステロン合成制御機構に関する検討2016
- Author(s)
  一町澄宜，沖健司，吉井陽子，久保田益亘，江草玄太郎，小武家和博，大久保博史，大野晴也，米田真康
- Organizer
  第24回日本ステロイドホルモン学会学術集会
- Place of Presentation
  大分
- Year and Date
  2016-12-04
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] 高ACTH血症下におけるアルドステロン動態を評価した一例2016
- Author(s)
  一町澄宜、沖健司、吉井陽子、久保田益亘、江草玄太郎、小武家和博、大久保博史、大野晴也、米田真康
- Organizer
  第26回臨床内分泌代謝Update
- Place of Presentation
  大宮
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] 遺伝子変異を認めないアルドステロン産生腺腫におけるアルドステロン合成機構の探索2016
- Author(s)
  一町澄宜、沖健司、小武家和博、吉井陽子、前田修作、大野晴也、米田真康、河野修興
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  京都
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アンギオテンシンII代謝産物によるアルドステロン合成制御機構に関する検討2015
- Author(s)
  一町澄宜、沖健司、小武家和博、岸本瑠衣、前田修作、大野晴也、米田真康、河野修興
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] アルドステロン分泌の分子機構2013
- Author(s)
  沖健司
- Organizer
  第86日本内分泌学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] miR-21 suppression attenuate cell proliferation and decrease aldosterone production via StAR repression in human adrenocortical cells2013
- Author(s)
  Oki K
- Organizer
  International Symposium of Aldosterone and Related Substances in Hypertension
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] アルドステロン分泌の分子機構2013
- Author(s)
  沖　健司
- Organizer
  日本内分泌学会総会
- Place of Presentation
  宮城県仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] miR-21 suppression attenuate cell proliferation and decrease aldosterone production via StAR repression in human adrenocortical cells2013
- Author(s)
  Kenji Oki, Maria W Plonczynski, Elise P Gomez-Sanchez, Celso E Gomez-Sanchez
- Organizer
  International Symposium of Aldosterone and Related Substances in Hypertension
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] Kir3.4(KCNJ5)によるアルドステロン分泌調節機構2012
- Author(s)
  沖健司
- Organizer
  第20回日本ステロイドホルモン学会
- Place of Presentation
  仙台市
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] The clinical and pathological characteristics of aldosterone producing adenoma with ATP1A1 mutation
- Author(s)
  Kazuhiro Kobuke, Kiyotaka Itcho, Kenji Oki, Rui Kishimoto, Shusaku Maeda, Haruya Ohno, Masayasu Yoneda, Nobuoki Kohno
- Organizer
  40th Meeting of the International Aldosterone Meeting
- Place of Presentation
  The Westin Chicago River North, Chicago, IL, USA
- Year and Date
  2015-06-19 – 2015-06-20
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] The Relationship Between Tumor Genotype and Clinical or Pathological Characteristics in Patients with Aldosterone Producing Adenoma
- Author(s)
  Kiyotaka Itcho, Kazuhiro Kobuke, Kenji Oki, Rui Kishimoto, Shusaku Maeda, Haruya Ohno, Masayasu Yoneda, Nobuoki Kohno
- Organizer
  The Endocrine society's 96th Annual Meeting and Expo
- Place of Presentation
  McCormick Place, Chicago, IL, USA
- Year and Date
  2015-06-21 – 2015-06-24
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] 原発性アルドステロン症の一次スクリーニングにおけるアルドステロン絶対値の有効性
- Author(s)
  沖　健司，小武家　和博，一町　澄宜，岸本　瑠衣，松本　武史，光波　直也，大久保　博史，前田　修作，大野　晴也，米田　真康，河野　修興
- Organizer
  第3回臨床高血圧フォーラム
- Place of Presentation
  広島，広島国際会議場
- Year and Date
  2015-05-24 – 2015-05-26
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] CYP11B2抗体を用いたアルドステロン産生腺腫の免疫組織化学による検討
- Author(s)
  小武家　和博，志和　亜華，沖　健司，米田　真康，粟屋　智一，中西　修平，河野　修興
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡，福岡国際会議場
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] ATP1A1体細胞変異を有するアルドステロン産生腺腫の臨床的および病理学的検討
- Author(s)
  一町　澄宜，沖　健司，小武家　和博，長野　学，毛利　麻衣子，志和　麻実，岸本　瑠衣，久保田　益亘，大久保　博史，前田　修作，大野　晴也，米田　真康，中西　修平，河野　修興
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡，福岡国際会議場
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26860707
[Presentation] Kir3.4(KCNJ5)によるアルドステロン分泌調節機構
- Author(s)
  沖健司，他
- Organizer
  第20回日本ステロイドホルモン学会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-24890308
[Presentation] 副腎皮質細胞の増殖およびアルドステロン合成におけるYPEL4の役割
- Author(s)
  沖　健司，Elise P Gomez-Sanchez, Celso E Gomez-Sanchez
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡，福岡国際会議場
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26860707

1. Nishimoto Koshiro (00365363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 小坂威雄 (30445407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 向井邦晃 (80229913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. Gomez-Sanchez Celso E.

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. Nagano Gaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. Itcho Kiyotaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 吉井陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
8. 大久保博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山崎岳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 脇裕典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大野晴也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 門脇孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 山内敏正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 荻島正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 加部泰明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小武家和博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Oki Kenji 沖 健司

沖 健司 オキ ケンジ

OKI Kenji 沖 健司

Research Projects

Research Products

Co-Researchers

The clarification of aldosterone production machinery and the identification of therapeutic factors based on the posttranscriptional regulationPrincipal Investigator

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Aldosterone production mechanisms mediated by ER calcium ion regulation.Principal Investigator

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Ealucidation of progression from aldosterone-producing cell cluster leading to aldosterone-producing adenoma

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The novel mechanism of aldosterone production in aldosterone-producing adenomaPrincipal Investigator

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The study of aldosterone production machinery by angiotensin II metabolitePrincipal Investigator

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[Journal Article] Endoplasmic Reticulum Chaperone Calmegin Is Upregulated in Aldosterone-Producing Adenoma and Associates With Aldosterone Production.2020

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[Journal Article] A Rare Case of IgG4-Related Disease Presenting as a Unilateral Severe Dacryoadenitis Complicated by Hypophysitis and Hypertrophic Pachymeningitis.2020

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[Journal Article] Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.2019

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[Journal Article] Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition.2019

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[Journal Article] Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency2019

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[Journal Article] Alteration of gut microbiota by a Westernized lifestyle and its correlation with insulin resistance in non-diabetic Japanese men.2019

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[Journal Article] Associations of nutrient intakes with obesity and diabetes mellitus in the longitudinal medical surveys of Japanese Americans.2019

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[Journal Article] Calneuron 1 Increased Ca2+in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing AdenomaNovelty and Significance2018

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[Journal Article] Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma2018

Oki Kenji 沖健司

沖健司オキケンジ

OKI Kenji 沖健司