Moroishi Toshiro 諸石寿朗

Researcher Number	30647722
Other IDs
Affiliation (Current)	2022: 熊本大学, 大学院生命科学研究部(医), 教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 熊本大学, 大学院生命科学研究部(医), 教授 2018: 熊本大学, 大学院生命科学研究部(医), 准教授
Review Section/Research Field	Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 44010:Cell biology-related / Basic Section 50010:Tumor biology-related / Transformative Research Areas, Section (III) Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 鉄代謝 / Hippoシグナル / 免疫 / ゲノム編集 / ライブラリースクリーニング / シグナル伝達経路 / ユビキチン / 免疫応答 / 免疫原性 / 自己免疫疾患 … More / Hippo経路 / がん / 腫瘍微小環境 / 代謝競合 / 器官形成 / 体外胚培養 / 組織の自律性 … More Except Principal Investigator 腸内細菌叢 / 食道癌 / 腫瘍免疫 / 腸内細菌 / Fusobacterium nucleatum / NFKB / Microbiome, Less

体外胚培養システムの構築による哺乳類器官形成期の組織自律性の解明Principal Investigator
- Principal Investigator
  
  諸石寿朗
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kumamoto University
腫瘍微小環境における鉄代謝の役割解明Principal Investigator
- Principal Investigator
  
  諸石寿朗
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kumamoto University
革新的治療開発を目指した腸内細菌Fusobacteriumと腫瘍免疫の網羅的解析
- Principal Investigator
  
  馬場祥史
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Towards an understanding of iron metabolism: comprehensive identification of iron-related moleculesPrincipal Investigator
- Principal Investigator
  
  Moroishi Toshiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kumamoto University
Elucidating the regulatory mechanisms and physiological functions of immunomodulation by the Hippo intracellular signaling pathwayPrincipal Investigator
- Principal Investigator
  
  Moroishi Toshiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kumamoto University

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] The Emerging Link between the Hippo Pathway and Non-coding RNA2020
- Author(s)
  Shimoda Mayuko、Moroishi Toshiro
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 43 Issue: 1 Pages: 1-10
- DOI
  10.1248/bpb.b19-00795
- NAID
  130007779182
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] Heat stress activates YAP/TAZ to induce the heat shock transcriptome2020
- Author(s)
  Luo Min、Meng Zhipeng、Moroishi Toshiro、Lin Kimberly C.、Shen Guobo、Mo Fei、Shao Bin、Wei Xiawei、Zhang Ping、Wei Yuquan、Guan Kun-Liang
- Journal Title
  
  Nature Cell Biology
  
  Volume: 22 Pages: 1447-1459
- DOI
  10.1038/s41556-020-00602-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] The Yin and Yang of tumour-derived extracellular vesicles in tumour immunity2020
- Author(s)
  Yamauchi Takayoshi、Moroishi Toshiro
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 169 Pages: 155-161
- DOI
  10.1093/jb/mvaa132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling2019
- Author(s)
  Verma, S., Yeddula, N., Soda, Y., Zhu, Q., Pao, G.M., Moresco, J., Diedrich, J.K., Hong, A., Plouffe, S., Moroishi, T., Guan, K.L., and Verma, I.M.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Pages: 7363-7370
- DOI
  10.1073/pnas.1822155116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.2019
- Author(s)
  Muto Y., Moroishi T., Ichihara K., Nishiyama M., Shimizu H., Eguchi H., Moriya K., Koike K., Mimori K., Mori M., Katayama Y., Nakayama KI.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 216 Issue: 4 Pages: 950-965
- DOI
  10.1084/jem.20180900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19433, KAKENHI-PROJECT-18K19509, KAKENHI-PUBLICLY-17H05953, KAKENHI-PROJECT-18H02747, KAKENHI-PROJECT-16K07177, KAKENHI-PROJECT-17K19608, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K20403, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-19H03715
[Journal Article] Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and α-Mannose as Adjuvants2019
- Author(s)
  Shinchi Hiroyuki、Yamaguchi Toru、Moroishi Toshiro、Yuki Masaharu、Wakao Masahiro、Cottam Howard B.、Hayashi Tomoko、Carson Dennis A.、Suda Yasuo
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 30 Pages: 2811-2821
- DOI
  10.1021/acs.bioconjchem.9b00560
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438, KAKENHI-PROJECT-17K17968, KAKENHI-PROJECT-19H00929
[Journal Article] Regulation of mitochondrial iron homeostasis by sideroflexin 22019
- Author(s)
  Non, E.E., *Wei, F.-Y., Ahmad, R.N.R., Yamamoto, T., Moroishi. T., *Tomizawa, K.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 69 Pages: 359-373
- DOI
  10.1007/s12576-018-0652-2
- NAID
  40021819064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0054, KAKENHI-PROJECT-18K19433, KAKENHI-PROJECT-18K19521, KAKENHI-PROJECT-18H02865, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02599
[Journal Article] Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity2019
- Author(s)
  Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, Osumi H, Terada K, Araki K, Takai T, Kamba T, Linehan WM, Moroishi T, Oike Y.
- Journal Title
  
  Genes Dev.
  
  Volume: 33 Pages: 1641-1656
- DOI
  10.1101/gad.329417.119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02438, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18K15246
[Journal Article] Hippo Pathway in Mammalian Adaptive Immune System2019
- Author(s)
  Yamauchi, T., Moroishi, T.
- Journal Title
  
  Cells
  
  Volume: 8 Pages: 398-398
- DOI
  10.3390/cells8050398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] Cell type-dependent function of LATS1/2 in cancer cell growth2018
- Author(s)
  Pan, W.W., Moroishi, T., Koo,J.H., and Guan, K.L.
- Journal Title
  
  Oncogene
  
  Volume: 38 Pages: 2595-2610
- DOI
  10.1038/s41388-018-0610-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] Assembly and activation of the Hippo signalome by FAT1 tumor suppressor2018
- Author(s)
  Martin, D., Degese, M.S., Vitale-Cross, L., Iglesias-Bartolome, R., Valera, J.L.C., Wang, Z., Feng, X., Yeerna, H., Vadmal, V., Moroishi, T., Thorne, R.F., Zaida, M., Siegele, B., Cheong, S.C., Molinolo, A.A., Samuels, Y., Tamayo, P., Guan, K.L., Lippman, S.M., Lyons, J.G., and Gutkind, J.S.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Pages: 2372-2372
- DOI
  10.1038/s41467-018-04590-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Journal Article] RAP2 mediates mechanoresponses of the Hippo pathway2018
- Author(s)
  Meng, Z., Qiu, Y., Lin, K.C., Kumar, A., Placone, J.K., Fang, C., Wang, K.C., Lu, S., Pan, M., Hong, A.W., Moroishi, T., Luo, M., Plouffe, S.W., Diao, Y., Ye, Z., Park, H.W., Wang, X., Yu, F.X., Chien, S., Wang, C.Y., Ren, B., Engler, A.J., and Guan, K.L.
- Journal Title
  
  Nature
  
  Volume: 560 Pages: 655-660
- DOI
  10.1038/s41586-018-0444-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] Regulation of anti-tumor immunity by extracellular vesicles and the Hippo pathway2020
- Author(s)
  諸石寿朗
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] がん細胞内のシグナルと細胞外小胞による腫瘍微小環境の制御2020
- Author(s)
  諸石寿朗
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] 細胞外小胞による免疫応答の制御2019
- Author(s)
  諸石寿朗
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] The Hippo pathway in cancer and immunity2019
- Author(s)
  Toshiro Moroishi
- Organizer
  TFC International Symposium: Cancer Etiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] Hippo経路と細胞外小胞によるがん免疫の制御2018
- Author(s)
  諸石寿朗
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02438
[Presentation] Targeting the Hippo intracellular signaling pathway for cancer immunotherapy2018
- Author(s)
  Moroishi, T.
- Organizer
  THE 45th NAITO CONFERENCE: Immunological and Molecular Bases for Cancer Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02438

1. 馬場祥史 (20599708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 馬場秀夫 (20240905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 澤智裕 (30284756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIMORI KOSHI

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. KADOMATSU Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 西山正章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 江口英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中山啓子

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# of Collaborated Products: 1 results
9. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 森正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 新地浩之

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# of Collaborated Products: 1 results
12. 隅田泰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 富澤一仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 魏范研

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 宮田敬士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 神波大己

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17. 馬場理也

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# of Collaborated Products: 1 results
18. 堀口晴紀

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# of Collaborated Products: 1 results

Moroishi Toshiro 諸石 寿朗

Research Projects

Research Products

Co-Researchers

体外胚培養システムの構築による哺乳類器官形成期の組織自律性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍微小環境における鉄代謝の役割解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

革新的治療開発を目指した腸内細菌Fusobacteriumと腫瘍免疫の網羅的解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Towards an understanding of iron metabolism: comprehensive identification of iron-related moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the regulatory mechanisms and physiological functions of immunomodulation by the Hippo intracellular signaling pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Emerging Link between the Hippo Pathway and Non-coding RNA2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Heat stress activates YAP/TAZ to induce the heat shock transcriptome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Yin and Yang of tumour-derived extracellular vesicles in tumour immunity2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and α-Mannose as Adjuvants2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of mitochondrial iron homeostasis by sideroflexin 22019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hippo Pathway in Mammalian Adaptive Immune System2019

Author(s)

Moroishi Toshiro 諸石寿朗