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Masamoto Yosuke  正本 庸介

Researcher Number 30706974
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8168-6459
Affiliation (Current) 2025: 東京大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help 2023: 東京大学, 医学部附属病院, 准教授
2017 – 2022: 東京大学, 医学部附属病院, 講師
2016: 東京大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Hematology
Except Principal Investigator
Laboratory medicine
Keywords
Principal Investigator
急性骨髄性白血病 / 白血病幹細胞 / プロテアソーム / adiponectin / 造血幹細胞 / 前白血病状態 / アディポネクチン
Except Principal Investigator
免疫血清学 / xMAPテクノロジー / 遺伝子導入 … More / HPA / 遺伝子導入細胞 / 抗HPA抗体 / HPA抗原 Less
  • Research Projects

    (4 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (6 People)
  •  Targeting the haematopoietic stem cell programme to understand the molecular basis of refractory acute myeloid leukaemia.Principal Investigator

    • Principal Investigator
      MASAMOTO YOSUKE
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  The role of proteasome in acute myeloid leukemiaPrincipal Investigator

    • Principal Investigator
      Masamoto Yosuke
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      The University of Tokyo
  •  Development of a new method for platelet antibody testing using transfected cell line

    • Principal Investigator
      Matsuhashi Mika
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      The University of Tokyo
      Saitama Prefectural University
  •  Mechanisms of preleukemic state due to abnormal hematopoietic environmentPrincipal Investigator

    • Principal Investigator
      Masamoto Yosuke
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Long-term remission after upfront autologous hematopoietic stem cell transplant for CD5+ diffuse large-B cell lymphoma2024

    • Author(s)
      Masamoto Y, Honda A, Shinozaki-Ushiku A, Ushiku T, Kurokawa M.
    • Journal Title

      Journal of Chemotherapy

      Volume: - Issue: 1 Pages: 85-93

    • DOI

      10.1080/1120009x.2024.2340147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Journal Article] A key to engineering natural killer cells to attack acute myeloid leukemia.2024

    • Author(s)
      Masamoto Y, Kurokawa M.
    • Journal Title

      Haematologica

      Volume: 109 Pages: 1302-4

    • DOI

      10.3324/haematol.2023.284272

    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Journal Article] Bone marrow involvement is a risk factor for infusion-related reactions in patients with follicular lymphoma treated by obinutuzumab.2023

    • Author(s)
      Masamoto Y, Shimura A, Honda A, Taoka K, Maki H, Kurokawa M.
    • Journal Title

      Annals of Hematology

      Volume: 102(1) Issue: 1 Pages: 243-244

    • DOI

      10.1007/s00277-022-05037-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Journal Article] EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment2023

    • Author(s)
      Masamoto Yosuke、Chiba Akira、Mizuno Hideaki、Hino Toshiya、Hayashida Hiroki、Sato Tomohiko、Bando Masashige、Shirahige Katsuhiko、Kurokawa Mineo
    • Journal Title

      Blood Advances

      Volume: 7 Issue: 8 Pages: 1577-1593

    • DOI

      10.1182/bloodadvances.2022008018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04805, KAKENHI-PUBLICLY-22H04686, KAKENHI-PROJECT-22K16297, KAKENHI-PROJECT-20H05686, KAKENHI-PROJECT-20H03708
  • [Journal Article] Dnmt3a R878C induces expansion of quiescent hematopoietic stem cell pool2022

    • Author(s)
      Higo T, Suzuki Y, Sato M, Koya J, Mizuno H, Miyauchi M, Masamoto Y, Kataoka K, Sumitomo Y, Tsuruta-Kishino T, Sato T, Kurokawa M.
    • Journal Title

      Experimental Hematology

      Volume: - Pages: 45-54

    • DOI

      10.1016/j.exphem.2022.02.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-20H03708
  • [Journal Article] Bone marrow involvement is a risk factor for infusion-related reactions in patients with follicular lymphoma treated by obinutuzumab.2022

    • Author(s)
      Masamoto Y, Taoka K, Maki H, Kurokawa M.
    • Journal Title

      Annals of Hematology

      Volume: 101(12) Issue: 12 Pages: 2795-2797

    • DOI

      10.1007/s00277-022-04987-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Journal Article] CAMK2G is identified as a novel therapeutic target for myelofibrosis.2022

    • Author(s)
      Miyauchi M, Sasaki K, Kagoya Y, Taoka K, Masamoto Y, Yamazaki S, Arai S, Mizuno H, Kurokawa M.
    • Journal Title

      Blood Advances

      Volume: 6 Issue: 5 Pages: 1585-1597

    • DOI

      10.1182/bloodadvances.2020003303

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-20K17369, KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-20H03708, KAKENHI-PROJECT-21K20827
  • [Journal Article] Evi1 upregulates Fbp1 and supports progression of acute myeloid leukemia through pentose phosphate pathway activation.2021

    • Author(s)
      Mizuno H, Koya J, Masamoto Y, Kagoya Y, Kurokawa M.
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 10 Pages: 4112-4126

    • DOI

      10.1111/cas.15098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-20K17369, KAKENHI-PROJECT-21H04805, KAKENHI-PROJECT-20H03708
  • [Journal Article] Tocilizumab for focal segmental glomerulosclerosis secondary to multicentric Castleman’s disease2019

    • Author(s)
      Ebisawa Kazutoshi、Masamoto Yosuke、Tokushige Junji、Nishi Hiroshi、Honda Kenjiro、Hinata Munetoshi、Toyama Kazuhiro、Nangaku Masaomi、Kurokawa Mineo
    • Journal Title

      Annals of Hematology

      Volume: 印刷中 Issue: 8 Pages: 1995-1997

    • DOI

      10.1007/s00277-019-03616-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-18K16110
  • [Journal Article] Long-term remission by brentuximab vedotin for non-mediastinal gray zone lymphoma refractory to autologous stem cell transplantation.2019

    • Author(s)
      Ebisawa K, Masamoto Y, Koya J, Shimura A, Shinozaki-Ushiku A, Toyama K, Nakazaki K, and Kurokawa M.
    • Journal Title

      Clinical Lymphoma, Myeloma and Leukemia

      Volume: 19(11) Issue: 11 Pages: e602-e604

    • DOI

      10.1016/j.clml.2019.08.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-18K16110
  • [Journal Article] A germline HLTF mutation in familial MDS induces DNA damage accumulation through impaired PCNA polyubiquitination2019

    • Author(s)
      Takaoka Kensuke、Kawazu Masahito、Koya Junji、Yoshimi Akihide、Masamoto Yosuke、Maki Hiroaki、Toya Takashi、Kobayashi Takashi、Nannya Yasuhito、Arai Shunya、Ueno Toshihide、Ueno Hironori、Suzuki Kenshi、Harada Hironori、Manabe Atsushi、Hayashi Yasuhide、Mano Hiroyuki、Kurokawa Mineo
    • Journal Title

      Leukemia

      Volume: 印刷中 Issue: 7 Pages: 1773-1782

    • DOI

      10.1038/s41375-019-0385-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-17K10130, KAKENHI-PROJECT-18K16110, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-17K16181, KAKENHI-PROJECT-18K07320
  • [Journal Article] Targeting chronic myeloid leukemia stem cells: can transcriptional program be a druggable target for cancers?2018

    • Author(s)
      Masamoto Y, Kurokawa M.
    • Journal Title

      Stem Cell Investigation

      Volume: 5 Pages: 10-10

    • DOI

      10.21037/sci.2018.03.05

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16110
  • [Journal Article] Modeling ASXL1 mutation revealed impaired hematopoiesis caused by derepression of p16Ink4a through aberrant PRC1-mediated histone modification2018

    • Author(s)
      Uni Masahiro、Masamoto Yosuke、Sato Tomohiko、Kamikubo Yasuhiko、Arai Shunya、Hara Eiji、Kurokawa Mineo
    • Journal Title

      Leukemia

      Volume: 33 Issue: 1 Pages: 191-204

    • DOI

      10.1038/s41375-018-0198-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-17H03597, KAKENHI-PROJECT-17H06632, KAKENHI-PROJECT-18K16110
  • [Journal Article] Adiponectin Enhances Quiescence Exit of Murine Hematopoietic Stem Cells and Hematopoietic Recovery Through mTORC1 Potentiation2017

    • Author(s)
      Masamoto Yosuke、Arai Shunya、Sato Tomohiko、Kubota Naoto、Takamoto Iseki、Kadowaki Takashi、Kurokawa Mineo
    • Journal Title

      STEM CELLS

      Volume: 35 Issue: 7 Pages: 1835-1848

    • DOI

      10.1002/stem.2640

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01196, KAKENHI-PROJECT-16K19567
  • [Presentation] Identification of ZFP91 As the Master Transcription Factor for EVI1 Gene Expression2023

    • Author(s)
      Hiroki Hayashida, Toshiya Hino, Ken Morita, Yosuke Masamoto, and Mineo Kurokawa,
    • Organizer
      第65回米国血液学会総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] EVI1 promotes immune-evasive microenvironment via cyclin D1 in acute myeloid leukemia2022

    • Author(s)
      Yosuke Masamoto, Akira Chiba, Hideaki Mizuno, Toshiya Hino Hiroki Hayashida, Mineo Kurokawa
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] EVI1 promotes immune-evasive microenvironment via cyclin D1 in acute myeloid leukemia2022

    • Author(s)
      Yosuke Masamoto, Akira Chiba, Toshiya Hino, Hiroki Hayashida, Hideaki Mizuno, Tomohiko Sato, Mineo Kurokawa
    • Organizer
      The 64th ASH Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] EVI1 promotes immune-evasive microenvironment via cyclin D1 in acute myeloid leukemia2022

    • Author(s)
      Yosuke Masamoto, Hideaki Mizuno, Mineo Kurokawa
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] EVI1-positive AML cells show distinct features and high dependency on ETS transcription factor ERG2021

    • Author(s)
      Yosuke Masamoto, Akira Chiba, Toshiaki Takezaki, Toshiya Hino, Hiroki Hayashida, Hideaki Mizuno, Tomohiko Sato, Mineo Kurokawa
    • Organizer
      第63回アメリカ血液学会総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] EVI1-positive AML stem cells survive cytotoxic chemotherapy and induce highly aggressive AML2020

    • Author(s)
      Yosuke Masamoto
    • Organizer
      第82回日本血液学会総会
    • Data Source
      KAKENHI-PROJECT-20H03708
  • [Presentation] Adipocyte-derived adiponectin enhances activation of hematopoietic stem cells by potentiating mTORC1 activation after myelotoxic injury2016

    • Author(s)
      Yosuke Masamoto, Shunya Arai, Tomohiko Sato, Iseki Takamoto, Naoto Kubota, Takashi Kadowaki, Mineo Kurokawa
    • Organizer
      国際幹細胞学会総会
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19567
  • 1.  Matsuhashi Mika (00759384)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  岡崎 仁 (80261973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  池田 敏之 (80322759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  西 裕志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  黒川 峰夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 6.  上野 敏秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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