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IKEDA Toshiyuki  池田 敏之

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Researcher Number 80322759
Other IDs
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Affiliation *help 2013 – 2018 : 東京大学, 医学部附属病院, 助教
2017 : 東京大学, 医学部附属病院, その他
2011 : 東京大学, 医学部・附属病院, 助教
2011 : 東京大学, 医学部附属病院, 特任助教
2009 : 東京大学, 医学部附属病院, 助教 … More
2009 : 東京大学, 医学部附属病院, 医員
2008 – 2009 : 東京大学, 医学部附属病院, 特任助教
2008 : The University of Tokyo, 医学部・附属病院, 特任助教
2007 : The University of Tokyo, Faculty of Medicine, Visiting Assistant Professor
2006 – 2007 : Tokyo Univ, Faculty of Medicine, Visiting Research Associate, 医学部附属病院, 客員教員
2006 : The university of Tokyo, Faculty of Medicine, Visiting Research Associate, 医学部附属病院, 客員教授
2005 : 東京大学, 医学部附属病院, 助手
2005 : The University of Tokyo, Hospital, Visiting Assistant Professor, 医学部附属病院, 客員助手
2004 – 2005 : 東京大学, 医学部附属病院, 寄附講座教員
2003 : 東京大学, 医学部附属病院, 助手
2000 : Univ.of Tokyo, Assistant, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Orthopaedic surgery
Except Principal Investigator
Orthopaedic surgery / Kidney internal medicine / Laboratory medicine
Keywords
Principal Investigator
p63 / 軟骨分化 / SOX6 / 転写因子 / SOX9 / 選択的スプライシング / SNX19 / S100B / S100A1 / ヒアルロン酸合成酵素タイプン … More / SOXトリオ / gene therapy / アポトーシス / Articular cartilage / がん抑制 / アデノウィルスベクター / レトロウィルスcDNAライブラリー / EMX / SOX5 / hyaluronic acid synthetase type 2 / SOXトリオ / 遺伝子治療 / 多血小板血漿 / 軟骨再生 / ATDC5 / PDGFβ / SRSF / SOX / クリオプレシピテート / 輸血療法 / adeno virus vector / S100 / hyaluronic acid / 変形性膝関節症 / スプライシング / マイクロアレイ / II型コラーゲン / ノッチシグナル / ヒアルロン酸 / 血小板由来増殖因子 / Chondrogenic differentiation / ヒアルロン酸合成酵素タイプ2 / 関節軟骨 / 軟骨代謝 / CILP / 血液型D抗原 / 変形性関節症 / Osleoarthritis / アデノウィルス / 血球分化 … More
Except Principal Investigator
骨 / 軟骨代謝 / 軟骨代謝学 / 軟骨分化 / 転写因子 / 軟骨 / 変形性関節症 / Transcription Factor / p63 / 転写制御 / HMG / 関節病学 / 椎間板 / カルシウム感知受容体 / Joint Development / 免疫血清学 / cGKII / 高カリウム血症 / regenerative medicine / 軟骨細胞 / 腎電解質代謝 / アディポネクチン / embryonic stem (ES) cells / 培養方法 / 軟骨内骨化 / 骨粗鬆症 / 再生医学 / 疫学 / chondrocyte differentiation / 遺伝子治療 / カルシウム代謝 / GDF5 / 関節軟骨細胞 / ATX / 分化十分条件 / 椎間板変性モデル / トランスジェニックマウス / 胚性幹細胞 / マルファン症候群 / 低Ca血症 / 遺伝子治療3 / Cartilage Metabolism / 胚性幹細胞(ES) / Adiponectin / 腎電解質異常 / 分化誘導 / 低カルシウム血症 / culture methods / 幹細胞 / 遺伝子 / 胚性幹(ES)細胞 / osteoblast differentiation / メカニカルストレス / FBN1 / 脂肪 / Sox9 / osteoporosis / 骨異栄養症 / HPA / Fbn1 / 整形外科学 / 側弯症 / 画像解析 / xMAPテクノロジー / WNT9A / 骨軟骨代謝学 / 関節再生 / バーター症候群 / 成長板 / ゲノム / 遺伝子導入 / 骨形成 / 骨分化 / 副甲状腺機能低下症 / Ca感知受容体 / lipid / 慢性腎不全 / bone / 腎機能低下 / ノックアウトマウス / 再生 / optimal differentiation condition / 椎間板変性 / 永久関節軟骨再生 / 高リン血症 Less
  • Research Projects

    (17results)
  • Research Products

    (118results)
  • Co-Researchers

    (48People)
  •  遺伝子導入細胞を用いた新たな血小板抗体検査法の開発Ongoing

    • Principal Investigator
      松橋 美佳
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Saitama Prefectural University
  •  軟骨・血球分化とがん抑制に関わるスプライシング制御機構の研究Principal InvestigatorOngoing

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  What causes overgrowth and scoliosis in Marfan syndrome?

    • Principal Investigator
      Taniguchi Yuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Investigation of molecular mechanisms of chondrogenesis by platelet rich plasmaPrincipal Investigator

    • Principal Investigator
      Ikeda Toshiyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Analyses of mechano-sensing pathways in chondrocytes using cyclic hydroctatic pressure model

    • Principal Investigator
      SAITO Taku
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms of joint formation by transcription factor SOX11

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.

    • Principal Investigator
      NAKAMURA Kozo
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      国立障害者リハビリテーションセンター(研究所)
      The University of Tokyo
  •  Where is the cause of Bartter's syndrome in the kidney?

    • Principal Investigator
      WATANABE Sumiyo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      The University of Tokyo
  •  新規軟骨分化誘導因子ZSCANCの機能解析Principal Investigator

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Research of the Molecular Network Regulating Endochondral Ossification

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Expression Cloning of Joint Regenerative Genes

    • Principal Investigator
      MATSUBARA Takehiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
      The University of Tokyo
  •  Regulation of Bone Formation by Adiponectin

    • Principal Investigator
      MATSUDAIRA Ko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  変形性関節症で誘導される軟骨特異的遺伝子CILPのプロモーター解析Principal Investigator

    • Principal Investigator
      池田 敏之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic Research for Upstream Molecules, Target molecules and Co-factors of the SOX trio, the Essential Transcription Factors for ChondrogenesisPrincipal Investigator

    • Principal Investigator
      IKEDA Toshiyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  新規軟骨分化制御因子cGK2シグナルの骨再正における機能解析とその標的分子の同定

    • Principal Investigator
      筑田 博隆
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Strategic study on osteoblast and chondrocyte differentiation from embryonic stem (ES) cells

    • Principal Investigator
      CHUNG Ung-il
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  The Studies towards Prevention of Osteoarthritis of the knee joint Using Adenovirus Vector Encording Hyaluronic Acid Synthe tase Type-2 GenePrincipal Investigator

    • Principal Investigator
      IKEDA Toshiyuki, 坪井 寿和
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The Univ. of Tokyo

All 2017 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Pilot study on novel blood containers with alternative plasticizers for red cell concentrate storage.2017

    • Author(s)
      Morishita Y, Nomura Y, Fukui C, Kawakami T, Ikeda T, Mukai T, Yuba T, Inamura KI, Yamaoka H, Miyazaki KI, Okazaki H, Haishima Y
    • Journal Title

      PLoS One

      Volume : 12

    • DOI
      10.1371/journal.pone.0185737
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Journal Article] Development of RBC transfusion indications and the collection of patient-specific pre-transfusion information.2017

    • Author(s)
      Yazer MH, van de Watering L, Okazaki H, Ikeda T, Nagura Y et al
    • Journal Title

      Vox Sang.

      Volume : 112

    • DOI
      10.1111/vox.12509
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Journal Article] Targeting Gene Expression to Specific Cells of Kidney Tubules in vivo, using Adenoviral Promoter Fragments.2017

    • Author(s)
      Sumiyo Watanabe , Toru Ogasawara, Yoshifuru Tamura, Taku Saito, Toshiyuki Ikeda, Nobuchika Suzuki, Tatsuo Shimosawa, Shigeru Shibata, Ung-il Chung, Masaomi Nangaku, Shunya Uchida
    • Journal Title

      PLOS One

      Volume : 12 Pages : 1-14

    • DOI
      10.1371/journal.pone.0168638
    • Peer Reviewed / Int'l Joint Research / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K09683, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-17H04310
  • [Journal Article] p63 Regulates Chondrocyte Survival in Articular Cartilage2017

    • Author(s)
      Taniguchi Y, Kawata M, Chang SH, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, and Saito T*
    • Journal Title

      Arthritis Rheumatol

      Volume : 69 Pages : 598-609

    • DOI
      10.1002/art.39976
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-16K10887, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-17H04310, KAKENHI-PROJECT-17H04311, KAKENHI-PROJECT-15K10462
  • [Journal Article] Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis2014

    • Author(s)
      Okada K, Saito T, et al.
    • Journal Title

      PLoS One

      Volume : 9

    • DOI
      10.1371/journal.pone.0115169
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592222, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670629, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-25713052
  • [Journal Article] β -Catenin regulates PTH/PTHrP receptor signals and chondrocyte hypertrophy through binding to its intracellular C-terminal region2013

    • Author(s)
      Yano, F. et al.
    • Journal Title

      Arthritis Rheum

      Volume : 72 Pages : 748-753

    • DOI
      10.1136/annrheumdis-2012-201745
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390416, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23659710, KAKENHI-PROJECT-24592254, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25713052
  • [Journal Article] Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium2013

    • Author(s)
      Hojo H, et al.
    • Journal Title

      J Biol Chem.

      Volume : 288 Pages : 9924-9932

    • DOI
      10.1074/jbc.m112.409342
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04835, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-24240069, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25462358, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
  • [Journal Article] C/EBP-βand RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2αas the inducer in chondrocytes2012

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Yano F, Ikeda T, Mabuchi A, Sapkota BR, Akune T, Nishida N, Yoshimura N, Nakagawa T, Tokunaga K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Hum Mol Genet

      Volume : 21 Pages : 1111-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice2012

    • Author(s)
      Fukai A, Kamekura S, Chikazu D, Nakagawa T, Hirata M, Saito T, Hosaka Y, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum-US

      Volume : 64 Pages : 198-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Aktl in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa A, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 62(3)

      Pages : 826-36

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume : 62 Pages : 826-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2αduring skeletal growth and osteoarthritis development2010

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, and Kawaguchi H
    • Journal Title

      Nat Med

      Volume : 16 Pages : 678-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, et.al.
    • Journal Title

      Arthritis Rheum. 62(3)

      Pages : 826-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions2010

    • Author(s)
      Fukai A, Kawamura N, Saito T, Oshima Y, Ikeda T, Kugimiya F, Higashikawa H, Yano F, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 62

      Pages : 826-836

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Ogasawara T, Ikeda T, et.al
    • Journal Title

      PLoS One. 4(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, et.al.
    • Journal Title

      Arthritis Rheum. 60(1)

      Pages : 166-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Ikeda T, Chung U, Kawaguchi H (その他9名)
    • Journal Title

      Arthritis Rheum 60

      Pages : 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of2009

    • Author(s)
      Hirata M, Ikeda T, Chung U, Kawaguchi H(その他9名)
    • Journal Title

      PLoS ONE 4

      Pages : 57-57

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Transcriptional induction of SOX9 by NF-kappaB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Ikeda T, Chung U, Kawaguchi H(その他5名)
    • Journal Title

      Osteoarthritis Cartilage, E-pub

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Screening of chondrogenic factors with a real-time fluoresce nce-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Ogasawara T., et.al
    • Journal Title

      Arthritis Rheum. Nov ; 60(11)

      Pages : 3314-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 4(2)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum. 60(11)

      Pages : 3314-23

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 60(1)

      Pages : 166-78

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      Arthritis Rheum

      Volume : 60 Pages : 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPβpromotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE

      Volume : 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Transcriptional induction of SOX9 by NF-κB family member RelA in chondrogenic cells2009

    • Author(s)
      Ushita M, Saito T, Ikeda T, Yano F, Higashikawa A, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      Osteoarthritis Cartilage 17

      Pages : 1065-1075

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene2009

    • Author(s)
      Higashikawa A, Saito T, Ikeda T, Kamekura S, Kawamura N, Kan A, Oshima Y, Ohba S, Ogata N, Takeshita K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages : 166-178

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2>2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      PLoS ONE 4

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene.2009

    • Author(s)
      Higashikawa A, Ikeda T, et al
    • Journal Title

      Arthritis Rheum. 60

      Pages : 166-178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] C/EBPbeta Promotes Transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.2009

    • Author(s)
      Hireta M, Ikeda T, et al.
    • Journal Title

      PLoS One 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, et.al.
    • Journal Title

      Arthritis Rheum. 60(11)

      Pages : 3314-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, et.al.
    • Journal Title

      PLoS One. 4(2)(Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Screening of chondrogenic factors by a real-time fluorescence monitoring cell line ATDC5-C2ER : Identification of sorting nexin 19 as a novel factor2009

    • Author(s)
      Kan A, Ikeda T, Saito T, Yano F, Fukai A, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      Arthritis Rheum 60

      Pages : 3314-3323

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, et.al.
    • Journal Title

      J Clin Invest. 118(7), Erratum in 118(8)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcription activator2008

    • Author(s)
      Tamiya H, Ikeda T, Jeong JH, Saito T, et.al.
    • Journal Title

      Gene. 416(1-2)(Epub)

      Pages : 53-60

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Ikeda T, Chung U, KawaguchiH (その他14名)
    • Journal Title

      J Clin Invest 118

      Pages : 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Ikeda T, Chung U, Kawaguchi H (その他11名)
    • Journal Title

      Dev Cell 14

      Pages : 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Biol Chem. 283(36)

      Pages : 24682-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      J Clin Invest. 118(7)

      Pages : 2506-15

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Patchedl haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI.
    • Journal Title

      Dev Cell. 14(5)

      Pages : 689-99

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, Fujii K, Miyajima T, Kuramochi A, Miyashita T, Oda H, Nakamura K, Takato T, Chung UI
    • Journal Title

      Dev Cell 14

      Pages : 689-699

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008

    • Author(s)
      Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, Ogata N, Hoshi K, Hofmann F, Woodgett JR, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Clin Invest 118

      Pages : 2506-2515

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 92008

    • Author(s)
      Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      J Biol Chem 283

      Pages : 24682-24689

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis2008

    • Author(s)
      Oshima Y, Akiyama T, Hikita A, Iwasawa M, Nagase Y, Nakamura M, Wakeyama H, Kawamura N, Ikeda T, Chung UI, Hennighausen L, Kawaguchi H, Nakamura K, Tanaka S
    • Journal Title

      J Biol Chem 283

      Pages : 26499-26508

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Analysis of the Runx2 promoter in osseous and non-osseous cells and identification of HIF2A as a potent transcriptional activator2008

    • Author(s)
      Tamiya H, Ikeda T, Jung JH, Saito T, Jung YK, Kawaguchi H, Ohba S, Chung UI, Choi JY
    • Journal Title

      Gene 416

      Pages : 53-60

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008

    • Author(s)
      Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, et.al.
    • Journal Title

      Dev Cell. 14(5)

      Pages : 689-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Aktl in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      PLoS One. 2(10)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T.
    • Journal Title

      Biochem Biophys Res Com in press

    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Shinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Tobe T, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI, and Kawaguchi H
    • Journal Title

      PLoS ONE 2(10)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Saito T, et.al.
    • Journal Title

      Biochem Biophys Res Commun. 357(2)(Epub)

      Pages : 383-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Akt1 in osteoblasts and osteoclasts controls bone remodeling2007

    • Author(s)
      Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, et.al.
    • Journal Title

      PLoS One. 2(10)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, et.al.
    • Journal Title

      EMBO Rep. 8(5)(Epub)

      Pages : 504-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590936
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T.
    • Journal Title

      Biochem Biophys Res Com (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Identification and characterization of the human SOX_6 promoter2007

    • Author(s)
      Ikeda T, Chung U, Kawaguchi H (その他7名)
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages : 383-90

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and characterization of the human SOX6 promoter2007

    • Author(s)
      Ikeda T, Saito T, Ushita M, Yano F, Kan A, Itaka K, Moro T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages : 383-390

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] S100A1 and B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Journal Title

      EMBO Rep 8

      Pages : 504-509

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Journal Title

      FASEB J 21

      Pages : 1777-1787

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Identification of a potent combination of osteogenic genes for bone regeneration using embryonic stem (ES) cell-based sensor2007

    • Author(s)
      Ohba S, Ikeda T, Kugimiya F, Yano F, Lichtler AC, Nakamura K, Takato T, Kawaguchi H, Chung UI.
    • Journal Title

      FASEB J. 21(8)

      Pages : 1777-87

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
    • Journal Title

      EMBO Rep. 8(5)

      Pages : 504-9

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and Characterization of the human SOX6 promoter.2007

    • Author(s)
      Toshiyuki Ikeda, et. al.
    • Journal Title

      Biochem Biophys Res Commun 357

      Pages : 383-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659374
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H.
    • Journal Title

      J Cell Biochem 99(1)

      Pages : 196-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Regulation of Bone Formation by Adiponectin Through Autocrine/Paracrine and Endocrine Pathways.2006

    • Author(s)
      Yusuke Shinoda, Masayuki Yamaguchi, Naoshi Ogata, Toru Akune, Naoto Kubota, Toshimasa Yamauchi, Yasuo Terauchi, Takashi Kadowaki, Yasuhiro Takeuchi, Seiji Fukumoto, Toshiyuki Ikeda, Kazuto Hoshi, Ung-il Chung, Kozo Nakamura, Hiroshi Kawaguchi
    • Journal Title

      Journal of Cellular Biochemistry 99

      Pages : 196-196

    • Data Source
      KAKENHI-PROJECT-17591551
  • [Journal Article] Carminerin contributes to chondrocyte calcification during endochondral ossification2006

    • Author(s)
      Yamada T, Kawano H, Koshizuka Y, Fukuda T, Yoshimura K, Kamekura S, Saito T, Ikeda T, Kawasaki Y, Azuma Y, Ikegawa S, Hoshi K, Chung UI, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Nat Med. 12(6)

      Pages : 665-70

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages : 337-340

    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005

    • Author(s)
      Yano F, Kugiyama F, Ohba S, Ikeda T, Chikuda H, Chung U
    • Journal Title

      Biochem Biophys Res Commun 333(4)

      Pages : 1300-1308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages : 337-340

    • Data Source
      KAKENHI-PROJECT-16659399
  • [Journal Article] Distinct roles of Sox5,Sox6,and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Chung U
    • Journal Title

      J Bone Miner Metab 338

      Pages : 872-879

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation.2005

    • Author(s)
      Ikeda T, Kawaguchi H, Kamekura S, Ogata N, Mori Y, Nakamura K, Ikegawa S, Chung U.
    • Journal Title

      J Bone Miner Metab 23

      Pages : 337-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005

    • Author(s)
      Yano F, Kugimiya F, Ohba S, Ikeda T, Chikuda H, Ogasawara T, Ogata N, Takato T, Nakamura K, Kawaguchi H, Chung U.
    • Journal Title

      Biochem Biophys Res Commun 333(4)

      Pages : 1300-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Distinct roles of Sox5,Sox6,and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages : 337-340

    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism (23)

      Pages : 337-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda, T
    • Journal Title

      Journal of Bone and Mineral Metabolism 23

      Pages : 337-340

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Distinct roles of Sox5, Sox6, and Sox9 in different stages of chondrogenic differentiation2005

    • Author(s)
      Ikeda Tら
    • Journal Title

      J Bone Miner Metab 23

      Pages : 337-340

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes2004

    • Author(s)
      Chikuda H, Kugimiya F, Ikeda T, Komeda K, Chung U
    • Journal Title

      Genes Dev 18

      Pages : 2418-2429

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9(the SOX trio)provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Kawaguchi H, Ikegawa S, Chung U
    • Journal Title

      Arthritis Rheum 50

      Pages : 3561-3573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Cyclic GMP-dependent kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.2004

    • Author(s)
      Chikuda H, Kugimiya F, Ikeda T, Ogasawara T, Shimoaka T, Kawano H, Kamekura S, Tsuchida A, Yokoi N, Nakamura K, Komeda K, Chung U, Kawaguchi H.
    • Journal Title

      Genes Dev 18

      Pages : 2418-2429

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kawano H, Sekine K, Matsumoto T, Fukuda T, Azuma Y, Chung U, Chambon P, Nakamura K, Kato S, Kawaguchi H.
    • Journal Title

      Arthritis Rheum 50

      Pages : 3561-3573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage2004

    • Author(s)
      Ikeda, T
    • Journal Title

      Arthritis Rheum (50)

      Pages : 3561-3573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage2004

    • Author(s)
      Ikeda, T
    • Journal Title

      Arthritis Rheum 50

      Pages : 3561-3573

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] 骨・軟骨分化決定因子の解析から再生医学へ2004

    • Author(s)
      鄭 雄一, 池田敏之, 川口 浩, 中村耕三, 高戸 毅
    • Journal Title

      分子リウマチ 2

      Pages : 22-26

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] The combination of SOX5, SOX6 and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.2004

    • Author(s)
      Ikeda T, Kamekura S, Mabuchi A, Kou I, Seki S, Takato T, Nakamura K, Kawaguchi H, Ikegawa S, Chung U.
    • Journal Title

      Arthritis Rheum 50

      Pages : 3561-3573

    • Data Source
      KAKENHI-PROJECT-15390452
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T et al.
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591549
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H.
    • Journal Title

      Nat Med (in press)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda, T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Identification and characterization of the human SOX6 promoter

    • Author(s)
      Ikeda T
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390430
  • [Journal Article] Identification and characterization of the human SOX6 promoter.

    • Author(s)
      Toshiyuki Ikeda, et al.
    • Journal Title

      Biochem Biophys Res Commun (印刷中)

    • Data Source
      KAKENHI-PROJECT-18209047
  • [Journal Article] Transcriptional regulation of endochondral ossification by HIF2A during skeletal growth and osteoarthritis development

    • Author(s)
      Saito T, Fukai A, Mabuchi A, Ikeda T, Yano F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, Nakamura K, Tokunaga K, Chung UI, Kawaguchi H
    • Journal Title

      Nature Med (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Journal Article] Title : Identification of oxytetracycline as a chondrogenic compound using a cell-based screening system

    • Author(s)
      Hojo H, Yano F, Ohba S, Igawa K, Nakajima K, Komiyama Y, Kan A, Ikeda T, Yonezawa T, Woo JT, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Journal Title

      J Bone Miner Metab (in press)

    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] WeakD/Delを引き起こすエクソンスキッピングのメカニズムと蛋白発現への影響2017

    • Author(s)
      三島由祐子, 池田敏之, 佐藤智彦, 正本庸介, 名倉豊, 曽根伸治, 岡崎仁
    • Organizer
      第64回 日本輸血・細胞治療学会
    • Place of Presentation
      京都府京都市
    • Year and Date
      2017-04-28
    • Data Source
      KAKENHI-PROJECT-16K10887
  • [Presentation] 脳神経外科手術における自己血輸血の安全性・有効性 その22016

    • Author(s)
      川端みちる、池田敏之 他
    • Organizer
      日本自己血輸血学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-11
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] 脳神経外科手術における自己血輸血の安全性・有効性 その12016

    • Author(s)
      高柳俊作、池田敏之 他
    • Organizer
      日本自己血輸血学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-03-11
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] Identification and characterization of molecular basis of Del mutations in the Japanese population2015

    • Author(s)
      Mishima Y, Sato T, Ikeda T et al.
    • Organizer
      AABB
    • Place of Presentation
      Anaheim
    • Year and Date
      2015-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462358
  • [Presentation] Comprehensive control of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis progression2009

    • Author(s)
      Saito T, Fukai A, Ikeda T, Yano F, Hirata M, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] A novel thienoindazole-derivative small compound induces chondrogenic differentiation without promoting hypertrophy through Runx1 (Young Investigator Award)2009

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Hojo H, Kimura A, Takeda S, Takato T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      31th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Denver, Colorado, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] NF-kappa B family member RelA/p65, a transcription factor of Sox9, is essential for chondrogenic differentiation and skeletal growth (Young Investigator Award)2009

    • Author(s)
      Itoh S, Saito T, Ushita M, Ikeda T, Yano F, Ogata N, Chung UI, Nakamura K, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Distinct transcriptional control of chondrocyte hypertrophy and cartilage degeneration by C/EBP-beta and Runx2 during endochondral ossification2009

    • Author(s)
      Hirata M, Kugimiya F, Fukai A, Saito T, Kan A, Higashikawa A, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Akt1 in chondrocytes controls cartilage calcification during osteophyte foration in osteoarthritis2009

    • Author(s)
      Fukai A, Kawamura N, Saito T, Ikeda T, Ogata N, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2009 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Monteral, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Development of high-throughput screening system for osteogenic drugs using cell-based sensor2008

    • Author(s)
      Hojo H, Igawa K, Ohba S, Yano F, Nakajima K, Komiyama K, Yonezawa T, Woo JT, Lichtler AC, Rowe DW, Ikeda T, Nakamura K, Kawaguchi H, Chung UI
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of a transcription factor p63 for transactivation of Wnt9a and Gdf5 causing joint cartilage formation2008

    • Author(s)
      Kan A, Ikeda T, Saito T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBPβ/p57^<Kip2> signaling maintains transition from proliferation to hypertrophic differentiation of chondrocytes during skeletal growth2008

    • Author(s)
      Hirata M, Kugimiya F, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] β-catenin directly binds to a specifc intracellular domain of PTH/PTHrP receptor and regulates the signaling in chondrocytes during endochondral ossification. (President's Award)2008

    • Author(s)
      Yano F, Chung UI, Ikeda T, Kawasaki Y, Kawaguchi H, Tawfeek HAW, Mahon MJ, Segre GV, Ogata N
    • Organizer
      30th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Montreal, Quebec, Canada
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] A Novel small thienoindazole-derivative compound promotes chondrogenic differentiation without inducing hypertrophy through production of Runx1 (Young Investigator Award)2008

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] C/EBP-beta promotes hypertrophic differentiation of chondrocytes through transactivation of p57^<Kip2> during endochonderal ossification (Young Investigator Award)2008

    • Author(s)
      Kugimiya F, Hirata M, Ohba S, Kawamura K, Ogasawara T, Kawasaki Y, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Hypoxia-inducible factor 2A (HIF2A) controls sequential steps in the late stage of endochondral ossification (Young Investigator Award)2008

    • Author(s)
      Saito T, Ikeda T, Kan A, Hirata M, Fukai A, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2008 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Rome, Italy
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 Plays a Central Role in Cartilage Development by Directly Regulating Key Genes for Chondrogenesis2007

    • Author(s)
      Tbshiyuld Ikeda
    • Organizer
      ASBMR 29thAnnual Meeting
    • Place of Presentation
      Hawah,USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] Identification of a novel chondrogenic factor Sorting Nexin 19 using a real-time fluorescence monitoring cell line ATDC5-S2RD52007

    • Author(s)
      Kan A, Ikeda T, Saito T, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional induction of SOX9 by NF-κB subunit p65 during chondrogenesis2007

    • Author(s)
      Ushita M, Ikeda T, Saito T, Kan A, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional regulation of type X collagen by Runx2 : Molecular network underlying chondrocyte hypertrophy causing osteoarthritis2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Runx1, co-activator of Sox5, Sox6 and Sox9 (the Sox trio) regulates chondrogenic differentiation2007

    • Author(s)
      Yano F, Ikeda T, Saito T, Ogata N, Takeda S, Kimura A, Ohba S, Kugimiya F, Nakamura K, Takato T, Kawaguchi H, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 plays a central role in cartilage development by directly regulating key genes for chondrogenesis2007

    • Author(s)
      Ikeda T, Kawaguchi H, Saito T, Kan A, Yano F, Ushita M, Kawasaki Y, Nakamura K, Chung UI
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63は軟骨の初期分化から後期分化までを統合的に支配するマスター転写因子である2007

    • Author(s)
      池田敏之ら
    • Organizer
      第25回日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] p63 Plays a Central Role in Cartilage Development by Directly Regulating Key Genes for Chondrogenesis2007

    • Author(s)
      Toshiyuki Ikeda et.al
    • Organizer
      The American Society for Bone and Mineral Research 29th Annual Meeting
    • Place of Presentation
      Hawaii,USA.
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] Hypoxia-inducible factor 2α induces type X collagen and promotes hypertrophic differentiation of chondrocytes2007

    • Author(s)
      Saito T, Ikeda T, Higashikawa A, Kawasaki Y, Kan A, Ushita M, Ohba S, Yano F, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      29th annual meeting of the American Society for Bone and Mineral Research (ASBMR)
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Identification of sorting nexin 19 as a novel chondrogenic factor by a real-time fluorescence monitoring cell line ATDC5-S2RD5 (Young Investigator Award)2007

    • Author(s)
      Kan A, Ikeda T, Saito T, Ushita M, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] Transcriptional induction of type X collagen expression and hypertrophic differentiation of chondrocytes by Runx2 during osteoarthritis progression (Young Investigator Award)2007

    • Author(s)
      Higashikawa A, Saito T, Kamekura S, Ohba S, Ikeda T, Nakamura K, Chung UI, Kawaguchi H
    • Organizer
      2007 World Congress on Osteoarthritis (OARSI)
    • Place of Presentation
      Ft. Lauderdale, Florida, USA
    • Data Source
      KAKENHI-PROJECT-19109007
  • [Presentation] p63 Plays a Centr al Role in Cartilage Development by Directly Regulating Key Genes for Ch ondrogenesis2007

    • Author(s)
      Ikeda T, et al.
    • Organizer
      ASBMR 29^<th> Annual Meeting
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2007-09-18
    • Data Source
      KAKENHI-PROJECT-18209047
  • [Presentation] 新規軟骨分化転因子ZFPACはC/EBPβと協調的に作用して軟骨分化を誘導する2007

    • Author(s)
      池田 敏之
    • Organizer
      第25回日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-02
    • Data Source
      KAKENHI-PROJECT-19659374
  • 1.  NAKAMURA Kozo (60126133)
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    # of Collaborated Products : 59results
  • 2.  CHUNG Ung-Il (30345053)
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    # of Collaborated Products : 71results
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  • 12.  筑田 博隆 (30345219)
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    # of Collaborated Projects : 1results
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