I Takashi 井隆司

Researcher Number	30733448
Other IDs	https://orcid.org/0000-0001-5167-5268
External Links
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 2015 – 2023: 長崎大学, 医歯薬学総合研究科(歯学系), 助教 2014: 長崎大学, 病院(歯学系), 医員
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry Except Principal Investigator Basic Section 57040:Regenerative dentistry and dental engineering-related / Medium-sized Section 57:Oral science and related fields
Keywords	Principal Investigator 唾液腺 / 再生医療 / 細胞治療 / 再生 / 血管内皮前駆細胞 / シェーグレン症候群 / 間葉系幹細胞 / CD34陽性細胞 / CD34 / 線維化 … More / 放射線性唾液腺萎縮症 / 抗炎症性細胞 / 再生医学 / エクソソーム / 放射線性唾液腺委縮症 … More Except Principal Investigator 細胞医薬 / マクロファージ / 老化細胞 / 再生 / 唾液腺 / 免疫細胞 / 病的老化 / 組織再生 Less

治療抵抗性老化導管細胞とマクロファージの相互作用を標的軸とした細胞医薬の基盤開発
- Principal Investigator
  
  住田吉慶
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nagasaki University
自己免疫疾患における所属リンパ節の免疫機能是正を標的軸としたデザイナー細胞の開発Principal Investigator
- Principal Investigator
  
  井隆司
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
病的老化組織からの組織再生を制御するデザイナー細胞医薬の創出
- Principal Investigator
  
  朝比奈泉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nagasaki University
Development of therapeutic agent for radiation salivary gland atrophy targeting the mechanism of differentiation of tissue-resident CD34-positive cellsPrincipal Investigator
- Principal Investigator
  
  I Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Novel treatment of salivary gland hypofunction by immunomodulatory anti-inflammatory cell population using co-culture of diseased inflammatory cellsPrincipal Investigator
- Principal Investigator
  
  I Takashi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Development of atrophic salivary gland regeneration therapy using exosome derived from vasculogenic conditioned-peripheral blood mononuclear cells induced by new culture systemPrincipal Investigator
- Principal Investigator
  
  I Takashi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University
Vasculogenic conditioned peripheral blood mononuclear cells rescue the radiation-inducedsalivary glandhypofunctionPrincipal Investigator
- Principal Investigator
  
  I Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagasaki University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Effective-mononuclear cell (E-MNC) therapy alleviates salivary gland damage by suppressing lymphocyte infiltration in Sjogren-like disease2023
- Author(s)
  Hasegawa Kayo、Raudales Jorge Luis Montenegro、I Takashi、Yoshida Takako、Honma Ryo、Iwatake Mayumi、Tran Simon D.、Seki Makoto、Asahina Izumi、Sumita Yoshinori
- Journal Title
  
  Frontiers in Bioengineering and Biotechnology
  
  Volume: 11
- DOI
  10.3389/fbioe.2023.1144624
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10142
[Journal Article] Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation2020
- Author(s)
  Takashi I, Yuichiro Ueda, Philipp Woersdoerfer, Yoshinori Sumita, Izumi Asahina, Sueleyman Erguen
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: 127 Issue: 11 Pages: 1467-1479
- DOI
  10.1007/s00702-020-02256-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10142
[Journal Article] Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.2019
- Author(s)
  I T, Sumita Y, Yoshida T, Honma R, Iwatake M, Raudales JLM, Shizuno T, Kuroshima S, Masuda H, Seki M, Tran SD, Asahara T, Asahina I.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: 10 Issue: 1 Pages: 304-304
- DOI
  10.1186/s13287-019-1414-7
- NAID
  120006988389
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09664, KAKENHI-PROJECT-19K08525, KAKENHI-PROJECT-18H02994, KAKENHI-PROJECT-18K17229
[Journal Article] Bone Marrow-derived Cell Therapy for Oral Mucosal Repair after Irradiation.2014
- Author(s)
  井隆司　住田吉慶　南里篤太郎　梅林真由美　Liu Y　Tran SD　朝比奈泉
- Journal Title
  
  Journal Dental of Research
  
  Volume: 93 Pages: 813-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] 放射線性障害唾液腺に対する Effective Mononuclear Cells (E-MNC) 治療の作用機序解析2023
- Author(s)
  叶井里歩, 井隆司, 本間遼, 魚返拓利, 関誠, 住田吉慶
- Organizer
  第22回再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022
- Author(s)
  井隆司, 本間遼, 魚返拓利, 関誠, 朝比奈泉, 住田吉慶
- Organizer
  第76回 NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022
- Author(s)
  井隆司, 本間遼, 魚返拓利, 関誠, 朝比奈泉, 住田吉慶
- Organizer
  日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022
- Author(s)
  井隆司, 本間遼, 魚返拓利, 関誠, 朝比奈泉, 住田吉慶
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] Next-generation regenerative therapy for radiation-injured salivary gland hypofunction2021
- Author(s)
  Takashi I
- Organizer
  IAOMS/Asian AOMS, NextGen Online Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] 放射線性萎縮唾液腺における組織常在性CD34陽性細胞の挙動解析2020
- Author(s)
  井隆司
- Organizer
  第65回日本口腔外科学会総会
- Data Source
  KAKENHI-PROJECT-20K10142
[Presentation] Translational study on effective-mononuclear cell therapy for radiation injured salivary gland.2019
- Author(s)
  Sumita Y, I T, Honma, R, Montenegro J, Iwatake M, Yoshida Y, Tran SD, Asahara T, Asahina I.
- Organizer
  Wurzburg Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17229
[Presentation] Effective peripheral blood mononuclear cells promote the regeneration of radiation injured salivary glands.2018
- Author(s)
  Sumita Yoshinori, 〇I Takashi, Iwatake Mayumi, Yoshida Takako, Tran SD, Asahara Takayuki, Asahina Izumi
- Organizer
  5th TERMIS World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17229
[Presentation] 放射線性唾液腺萎縮症に対する末梢血由来再生アソシエイト細胞による細胞治療の試み2017
- Author(s)
  井隆司, 住田吉慶, 岩竹真弓, 朝比奈泉
- Organizer
  長崎障害者支援再生医療研究会
- Data Source
  KAKENHI-PROJECT-16K20590
[Presentation] 血管内皮前駆細胞を主体とした末梢血濃縮細胞群による放射線性萎縮唾液腺再生療法のメカニズムの解析2016
- Author(s)
  井隆司
- Organizer
  日本唾液腺学会総会
- Place of Presentation
  文京学院大学本郷キャンパス（東京都・文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-16K20590
[Presentation] 血管内皮前駆細胞を主体とした末梢血濃縮細胞群(QQ-EPCs)による萎縮唾液腺再生療法の開発2016
- Author(s)
  井隆司,住田吉慶,増田治史,浅原孝之,朝比奈泉
- Organizer
  日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] Mechanism analysis of cell therapy with vasculogenic conditioned peripheral blood mononuclear cells for the radiation-induced salivary gland hypofunction2016
- Author(s)
  井隆司,住田吉慶,増田治史,Simon Tran,浅原孝之,朝比奈泉
- Organizer
  国際幹細胞学会(ISSCR)
- Place of Presentation
  サンフランシスコ(アメリカ)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] Mechanism analysis of cell therapy with vasculogenic conditioned peripheral blood mononuclear cells for the radiation-induced salivary gland hypofunction2016
- Author(s)
  Takashi I, Yoshinori Sumita, Haruchika Masuda, Shinichiro Kuroshima, Simon D Tran, Takayuki Asahara, Izumi Asahina
- Organizer
  国際幹細胞学会(ISSCR)
- Place of Presentation
  サンフランシスコ(米国)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20590
[Presentation] Vasculogenic Conditioned Peripheral Blood Mononuclear Cells Rescue the Radiation-Induced Salivary Gland Hypofun2015
- Author(s)
  井隆司,住田吉慶,増田治史,Simon Tran,浅原孝之,朝比奈泉
- Organizer
  国際幹細胞学会(ISSCR)
- Place of Presentation
  ストックホルム(スウェーデン)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] 血管内皮前駆細胞を主体とした末梢血濃縮細胞群による萎縮唾液腺再生療法の開発2015
- Author(s)
  井隆司,住田吉慶,朝比奈泉
- Organizer
  日本口腔外科学会総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] CELL THERAPY FOR RADIATION-INDUCED SALIVARY GLAND HYPOFUNCTION WITH PERIPHERAL BLOOD DERIVED EPC
- Author(s)
  井隆司
- Organizer
  ISSCR(国際幹細胞学会)
- Place of Presentation
  ストックホルム(スウェーデン)
- Year and Date
  2015-06-24 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-26893199
[Presentation] 血管内皮前駆細胞細胞を主体とした末梢血濃縮細胞群による萎縮唾液腺再生療法の開発
- Author(s)
  井隆司
- Organizer
  再生医療学会総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26893199

1. 住田吉慶 (50456654)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. 朝比奈泉 (30221039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 黒嶋伸一郎 (40443915)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 魚返拓利 (70548776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大庭伸介 (20466733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 梅田雅孝 (20750053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松本拡高 (90782045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 各務秀明 (80242866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

I Takashi 井 隆司

Research Projects

Research Products

Co-Researchers

治療抵抗性老化導管細胞とマクロファージの相互作用を標的軸とした細胞医薬の基盤開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自己免疫疾患における所属リンパ節の免疫機能是正を標的軸としたデザイナー細胞の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

病的老化組織からの組織再生を制御するデザイナー細胞医薬の創出

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of therapeutic agent for radiation salivary gland atrophy targeting the mechanism of differentiation of tissue-resident CD34-positive cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel treatment of salivary gland hypofunction by immunomodulatory anti-inflammatory cell population using co-culture of diseased inflammatory cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of atrophic salivary gland regeneration therapy using exosome derived from vasculogenic conditioned-peripheral blood mononuclear cells induced by new culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Vasculogenic conditioned peripheral blood mononuclear cells rescue the radiation-inducedsalivary glandhypofunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effective-mononuclear cell (E-MNC) therapy alleviates salivary gland damage by suppressing lymphocyte infiltration in Sjogren-like disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Bone Marrow-derived Cell Therapy for Oral Mucosal Repair after Irradiation.2014

Author(s)

Journal Title

Data Source

[Presentation] 放射線性障害唾液腺に対する Effective Mononuclear Cells (E-MNC) 治療の作用機序解析2023

Author(s)

Organizer

Data Source

[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022

Author(s)

Organizer

Data Source

[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022

Author(s)

Organizer

Data Source

[Presentation] DAMPs排除機能を備えたEffectively Mononuclear Cell（E-MNC）は放射線性萎縮唾液腺の再生を促進する2022

Author(s)

I Takashi 井隆司

[Presentation] 放射線性唾液腺萎縮症に対する末梢血由来再生アソシエイト細胞による細胞治療の試み2017